A profile of neuropsychological deficits in alcoholic women.
paper
Cited
Public
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- Authors
- Sullivan, Edith V; Fama, Rosemary; Rosenbloom, Margaret J; Pfefferbaum, Adolf
- Year
- 2002
- Journal
- Neuropsychology
- PMID
- 11853359
- DOI
- 10.1037//0894-4105.16.1.74
Neuropsychological deficits, most notable in executive, visuospatial, and functions of gait and balance, are detectable in alcoholic men even after a month of sobriety. Less well established are the severity and profile of persisting deficits in alcoholic women. The authors used an extensive test battery to examine cognitive and motor functions in 43 alcoholic women who were sober, on average, for 3.6 months. Functions most severely affected in alcoholic women involved visuospatial and verbal and nonverbal working memory processes as well as gait and balance. Areas of relative sparing were executive functions, declarative memory, and upper-limb strength and speed. The authors found that lifetime alcohol consumption was related to impairment severity on Block Design (Wechsler Adult Intelligence Scale-Revised, D. Wechsler, 1981) and verbal and nonverbal working memory, suggesting a dose effect of alcohol abuse. The alcohol-related deficits in working memory, visuospatial, and balance implicate disruption of prefrontal, superior parietal, and cerebellar brain systems.
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| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Binge alcohol and the neuroendocrinology of the aging female. | Leasure JL et al. | β | 2025 | β |
| Cognitive impairment in alcohol use disorder and clinical practice guidelines for management of long-stay alcohol use disorder patients. | Praharaj SK et al. | β | 2025 | β |
| Embodied Cognition and Alcohol Use Disorder: Frequency of Impairments and Relationship to Neurocognitive Assessments. | Bell MD et al. | β | 2025 | β |
| What Chemsex does to the brain - neural correlates (ERP) regarding decision making, impulsivity and hypersexuality. | Schwarz J et al. | β | 2025 | β |
| Neuroimmune Activation and Microglia Reactivity in Female Rats Following Alcohol Dependence. | Melbourne JK et al. | β | 2024 | β |
| The combination of donepezil and cognitive training for improving treatment outcomes for alcohol use disorder: Design of a randomized controlled trial. | Yoon G et al. | β | 2024 | β |
| Association of Alcohol Consumption with Cognition in Older Population: The A4 Study. | Nallapu BT et al. | β | 2023 | β |
| Astrocyte Reactivity and Neurodegeneration in the Female Rat Brain Following Alcohol Dependence. | Guerin SP et al. | β | 2023 | β |
| Corpus Callosum Atrophy in Alcohol-Dependent Men with Memory Disorders and Visual Attention Difficulties. | Nowaczyk N et al. | β | 2023 | β |
| Cognitive impairment in the co-occurrence of alcohol dependence and major depression: neuropsychological assessment and event-related potentials analyses. | Flores-Medina Y et al. | β | 2022 | β |
| Cognitive and motor deficits in older adults with HIV infection: Comparison with normal ageing and Parkinson's disease. | MΓΌller-Oehring EM et al. | β | 2021 | β |
| Visuoperceptive Impairments in Severe Alcohol Use Disorder: A Critical Review of Behavioral Studies. | Creupelandt C et al. | β | 2021 | β |
| Alcohol's Unique Effects on Cognition in Women: A 2020 (Re)view to Envision Future Research and Treatment. | Fama R et al. | β | 2020 | β |
| Altered neural dynamics in occipital cortices serving visual-spatial processing in heavy alcohol users. | Lew BJ et al. | β | 2020 | β |
| Association between change in lifestyle and cognitive functions among elderly Koreans: findings from the Korean longitudinal study of aging (2006-2016). | Lee HJ et al. | β | 2020 | β |
| Cognitive Impairments in Early-Detoxified Alcohol-Dependent Inpatients and Their Associations with Socio-Demographic, Clinical and Psychological Factors: An Exploratory Study. | Caneva S et al. | β | 2020 | β |
| Double-blind, placebo-controlled trial of mifepristone on cognition and depression in alcohol dependence. | Donoghue K et al. | β | 2020 | β |
| Frequency of Recent Binge Drinking Is Associated With Sex-Specific Cognitive Deficits: Evidence for Condition-Dependent Trait Expression in Humans. | Hone LSE et al. | β | 2020 | β |
| Neurocognitive performance in alcohol use disorder using the NIH toolbox: Role of severity and sex differences. | Meredith LR et al. | β | 2020 | β |
| Neuropsychological dysfunctions among chronic schizophrenia patients, alcohol dependence cases, and normal subjects: A comparative study. | Dixit V et al. | β | 2020 | β |
| Cognitive training as a component of treatment of alcohol use disorder: A review. | Nixon SJ et al. | β | 2019 | β |
| Neurological, nutritional and alcohol consumption factors underlie cognitive and motor deficits in chronic alcoholism. | Fama R et al. | β | 2019 | β |
| The Aging Brain With HIV Infection: Effects of Alcoholism or Hepatitis C Comorbidity. | Zahr NM | β | 2018 | β |
| Contributions to Understanding the Neuropsychology of Alcoholism: An INS Legacy. | Sullivan EV | β | 2017 | β |
| Differences in the verbal fluency, working memory and executive functions in alcoholics: Short-term vs. long-term abstainers. | Nowakowska-DomagaΕa K et al. | β | 2017 | β |
| Executive Functions, Memory, and Social Cognitive Deficits and Recovery in Chronic Alcoholism: A Critical Review to Inform Future Research. | Le Berre AP et al. | β | 2017 | β |
| Persistent negative effects of alcohol drinking on aspects of novelty-directed behavior in male rhesus macaques. | Chandler CM et al. | β | 2017 | β |
| Perspectives on fronto-fugal circuitry from human imaging of alcohol use disorders. | Zahr NM et al. | β | 2017 | β |
| Women and Addiction. | Ait-Daoud N et al. | β | 2017 | β |
| Changes in the female arcuate nucleus morphology and neurochemistry after chronic ethanol consumption and long-term withdrawal. | RebouΓ§as ECC et al. | β | 2016 | β |
| Current Heavy Alcohol Consumption is Associated with Greater Cognitive Impairment in Older Adults. | Woods AJ et al. | β | 2016 | β |
| Double-blind, 12 month follow-up, placebo-controlled trial of mifepristone on cognition in alcoholics: the MIFCOG trial protocol. | Donoghue K et al. | β | 2016 | β |
| Visual and verbal learning deficits in Veterans with alcohol and substance use disorders. | Bell MD et al. | β | 2016 | β |
| Dendritic remodeling of hippocampal neurons is associated with altered NMDA receptor expression in alcohol dependent rats. | Staples MC et al. | β | 2015 | β |
| Executive Functioning in Alcohol Use Studies: A Brief Review of Findings and Challenges in Assessment. | Day AM et al. | β | 2015 | β |
| Neural mechanisms of high-risk decisions-to-drink in alcohol-dependent women. | Arcurio LR et al. | β | 2015 | β |
| [Alcohol induced cognitive deficits]. | Weiss E et al. | β | 2014 | β |
| Are visual impairments responsible for emotion decoding deficits in alcohol-dependence? | D'Hondt F et al. | β | 2014 | β |
| Below and beyond the recognition of emotional facial expressions in alcohol dependence: from basic perception to social cognition. | D'Hondt F et al. | β | 2014 | β |
| Cognitive control in alcohol use disorder: deficits and clinical relevance. | Wilcox CE et al. | β | 2014 | β |
| Impaired fear recognition and attentional set-shifting is associated with brain structural changes in alcoholic patients. | Trick L et al. | β | 2014 | β |
| Profiles of impaired, spared, and recovered neuropsychologic processes in alcoholism. | Oscar-Berman M et al. | β | 2014 | β |
| Social cognition deficits and associations with drinking history in alcoholic men and women. | Valmas MM et al. | β | 2014 | β |
| ΞΌ-Opioid receptors mediate the effects of chronic ethanol binge drinking on the hippocampal neurogenic niche. | Contet C et al. | β | 2014 | β |
| Brain volumes and neuropsychological performance are related to current smoking and alcoholism history. | Luhar RB et al. | β | 2013 | β |
| Neurobiological signatures of alcohol dependence revealed by protein profiling. | Gorini G et al. | β | 2013 | β |
| The Interplay between the Hippocampus and Amygdala in Regulating Aberrant Hippocampal Neurogenesis during Protracted Abstinence from Alcohol Dependence. | Mandyam CD | β | 2013 | β |
| Neurocognitive deficits in male alcoholics: an ERP/sLORETA analysis of the N2 component in an equal probability Go/NoGo task. | Pandey AK et al. | β | 2012 | β |
| Recovery of cognitive functioning in patients with co-occurring bipolar disorder and alcohol dependence during early remission from an acute mood episode. | Levy B et al. | β | 2012 | β |
| Selective neurocognitive deficits and poor life functioning are associated with significant depressive symptoms in alcoholism-HIV infection comorbidity. | Sassoon SA et al. | β | 2012 | β |
| Altered fronto-cerebellar connectivity in alcohol-naΓ―ve youth with a family history of alcoholism. | Herting MM et al. | β | 2011 | β |
| Brain volumetric measures in alcoholics: a comparison of two segmentation methods. | Oscar-Berman M et al. | β | 2011 | β |
| Neurodegenerative properties of chronic pain: cognitive decline in patients with chronic pancreatitis. | Jongsma ML et al. | β | 2011 | β |
| Nicotine effects on immediate and delayed verbal memory after substance use detoxification. | Gilbertson R et al. | β | 2011 | β |
| Persistent but less severe ataxia in long-term versus short-term abstinent alcoholic men and women: a cross-sectional analysis. | Smith S et al. | β | 2011 | β |
| Reduced cortical thickness in abstinent alcoholics and association with alcoholic behavior. | Fortier CB et al. | β | 2011 | β |
| Acute ethanol effects on brain activation in low- and high-level responders to alcohol. | Trim RS et al. | β | 2010 | β |
| Cognitive performance in treatment-naΓ―ve active alcoholics. | Smith S et al. | β | 2010 | β |
| Low effective organizational strategies in visual memory performance of unmedicated alcoholics during early abstinence. | Daig I et al. | β | 2010 | β |
| Mechanisms of postural control in alcoholic men and women: biomechanical analysis of musculoskeletal coordination during quiet standing. | Sullivan EV et al. | β | 2010 | β |
| Physiological and focal cerebellar substrates of abnormal postural sway and tremor in alcoholic women. | Sullivan EV et al. | β | 2010 | β |
| The effect of moderate to heavy alcohol consumption on neuropsychological performance as measured by the repeatable battery for the assessment of neuropsychological status. | Green A et al. | β | 2010 | β |
| Transcallosal white matter degradation detected with quantitative fiber tracking in alcoholic men and women: selective relations to dissociable functions. | Pfefferbaum A et al. | β | 2010 | β |
| Contribution of Regional White Matter Integrity to Visuospatial Construction Accuracy, Organizational Strategy, and Memory for a Complex Figure in Abstinent Alcoholics. | Rosenbloom MJ et al. | β | 2009 | β |
| From the brain to bad behaviour and back again: neurocognitive and psychobiological mechanisms of driving while impaired by alcohol. | Brown TG et al. | β | 2009 | β |
| Frontal brain dysfunction in alcoholism with and without antisocial personality disorder. | Oscar-Berman M et al. | β | 2009 | β |
| Global-local interference is related to callosal compromise in alcoholism: a behavior-DTI association study. | MΓΌller-Oehring EM et al. | β | 2009 | β |
| Initiating moderate to heavy alcohol use predicts changes in neuropsychological functioning for adolescent girls and boys. | Squeglia LM et al. | β | 2009 | β |
| Repeated ethanol exposure affects the acquisition of spatial memory in adolescent female rats. | Sircar R et al. | β | 2009 | β |
| Silent trace eliminates differential eyeblink learning in abstinent alcoholics. | Fortier CB et al. | β | 2009 | β |
| The impacts of substance abuse and dependence on neuropsychological functions in a sample of patients from Saudi Arabia. | Al-Zahrani MA et al. | β | 2009 | β |
| Working and episodic memory in HIV infection, alcoholism, and their comorbidity: baseline and 1-year follow-up examinations. | Fama R et al. | β | 2009 | β |
| Alcohol and estrogen replacement therapy in postmenopausal women. Direct and mediated effects on cognitive component processes. | Tivis LJ et al. | β | 2008 | β |
| Delay discrimination and reversal eyeblink classical conditioning in abstinent chronic alcoholics. | Fortier CB et al. | β | 2008 | β |
| Effects of the glucocorticoid antagonist, mifepristone, on the consequences of withdrawal from long term alcohol consumption. | Jacquot C et al. | β | 2008 | β |
| Frontal Callosal Fiber Integrity Selectively Predicts Coordinated Psychomotor Performance in Chronic Alcoholism. | Rosenbloom MJ et al. | β | 2008 | β |
| Magnetic resonance imaging of the living brain: evidence for brain degeneration among alcoholics and recovery with abstinence. | Rosenbloom MJ et al. | β | 2008 | β |
| Neuroinflammation as a neurotoxic mechanism in alcoholism: commentary on "Increased MCP-1 and microglia in various regions of human alcoholic brain". | Sullivan EV et al. | β | 2008 | β |
| The role of selected factors in the development and consequences of alcohol dependence. | Gilbertson R et al. | β | 2008 | β |
| Alcohol: effects on neurobehavioral functions and the brain. | Oscar-Berman M et al. | β | 2007 | β |
| Cognitive performance in long-term abstinent elderly alcoholics. | Fein G et al. | β | 2007 | β |
| Component cognitive and motor processes of the digit symbol test: differential deficits in alcoholism, HIV infection, and their comorbidity. | Sassoon SA et al. | β | 2007 | β |
| Effects of alcohol and combined marijuana and alcohol use during adolescence on hippocampal volume and asymmetry. | Medina KL et al. | β | 2007 | β |
| Gender differences in neurocognitive functioning among alcohol-dependent Russian patients. | Flannery B et al. | β | 2007 | β |
| Genuine episodic memory deficits and executive dysfunctions in alcoholic subjects early in abstinence. | Pitel AL et al. | β | 2007 | β |
| Improvement in memory and static balance with abstinence in alcoholic men and women: selective relations with change in brain structure. | Rosenbloom MJ et al. | β | 2007 | β |
| Is the P300 deficit in alcoholism associated with early visual impairments (P100, N170)? An oddball paradigm. | Maurage P et al. | β | 2007 | β |
| The relationship between brain morphometry and neuropsychological performance in alcohol dependence. | Jang DP et al. | β | 2007 | β |
| Brain atrophy in long-term abstinent alcoholics who demonstrate impairment on a simulated gambling task. | Fein G et al. | β | 2006 | β |
| Cognitive performance in long-term abstinent alcoholic individuals. | Fein G et al. | β | 2006 | β |
| Executive function and memory in relation to olfactory deficits in alcohol-dependent patients. | Rupp CI et al. | β | 2006 | β |
| Suppression of early evoked gamma band response in male alcoholics during a visual oddball task. | Padmanabhapillai A et al. | β | 2006 | β |
| Alcoholic neurobiology: changes in dependence and recovery. | Crews FT et al. | β | 2005 | β |
| Chronic alcohol exposure reduces hippocampal neurogenesis and dendritic growth of newborn neurons. | He J et al. | β | 2005 | β |
| Gender and adolescent alcohol use disorders on BOLD (blood oxygen level dependent) response to spatial working memory. | Caldwell LC et al. | β | 2005 | β |
| Neurocircuitry in alcoholism: a substrate of disruption and repair. | Sullivan EV et al. | β | 2005 | β |
| Alcohol intoxication effects on visual perception: an fMRI study. | Calhoun VD et al. | β | 2004 | β |
| Women with substance abuse concerns. | Kovalesky A | β | 2004 | β |
| Diffusion tensor imaging in normal aging and neuropsychiatric disorders. | Sullivan EV et al. | β | 2003 | β |
| Speed and efficiency but not accuracy or timing deficits of limb movements in alcoholic men and women. | Sullivan EV et al. | β | 2002 | β |