The molecular logic of endocannabinoid signalling.
paper
Cited
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- Authors
- Piomelli, Daniele
- Year
- 2003
- Journal
- Nature reviews. Neuroscience
- PMID
- 14595399
- DOI
- 10.1038/nrn1247
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|---|---|---|---|---|
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| Cannabidiol and the Remainder of the Plant Extract Modulate the Effects of Ξ9-Tetrahydrocannabinol on Fear Memory Reconsolidation. | Murkar A et al. | β | 2019 | β |
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| Cannabinoid CB<sub>1</sub> Receptors Inhibit Gut-Brain Satiation Signaling in Diet-Induced Obesity. | Argueta DA et al. | β | 2019 | β |
| Cannabinoid CB<sub>1</sub> receptors in the amygdalar cholecystokinin glutamatergic afferents to nucleus accumbens modulate depressive-like behavior. | Shen CJ et al. | β | 2019 | β |
| Cannabinoid receptor-mediated modulation of inhibitory inputs to mitral cells in the main olfactory bulb. | Wang ZJ et al. | β | 2019 | β |
| Cannabis for refractory epilepsy in children: A review focusing on CDKL5 Deficiency Disorder. | Dale T et al. | β | 2019 | β |
| CB1 Receptors in the Anterior Piriform Cortex Control Odor Preference Memory. | Terral G et al. | β | 2019 | β |
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| Effects of cannabinoids on the development of chick embryos in ovo. | Gustafsson SB et al. | β | 2019 | β |
| Elevation of endocannabinoids in the brain by synthetic cannabinoid JWH-018: mechanism and effect on learning and memory. | Li RS et al. | β | 2019 | β |
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| Endocannabinoid System in Hepatic Glucose Metabolism, Fatty Liver Disease, and Cirrhosis. | Bazwinsky-Wutschke I et al. | β | 2019 | β |
| From adolescence to late aging: A comprehensive review of social behavior, alcohol, and neuroinflammation across the lifespan. | Perkins AE et al. | β | 2019 | β |
| Marijuana use and major depressive disorder are additively associated with reduced verbal learning and altered cortical thickness. | Radoman M et al. | β | 2019 | β |
| Modulation of the Cannabinoid System: A New Perspective for the Treatment of the Alzheimer's Disease. | Talarico G et al. | β | 2019 | β |
| Molecular neuroscience at its "high": bibliometric analysis of the most cited papers on endocannabinoid system, cannabis and cannabinoids. | Yeung AWK et al. | β | 2019 | β |
| Myosalpinx Contractions Are Essential for Egg Transport Along the Oviduct and Are Disrupted in Reproductive Tract Diseases. | Dixon RE et al. | β | 2019 | β |
| Neurobiological effects of aerobic exercise, with a focus on patients with schizophrenia. | Maurus I et al. | β | 2019 | β |
| Noradrenergic depletion causes sex specific alterations in the endocannabinoid system in the Murine prefrontal cortex. | Urquhart MA et al. | β | 2019 | β |
| Novel Optogenetic Approaches in Epilepsy Research. | Cela E et al. | β | 2019 | β |
| Photorelease of 2-Arachidonoylglycerol in Live Cells. | Laguerre A et al. | β | 2019 | β |
| Plasma concentrations of oleoylethanolamide in a primary care sample of depressed patients are increased in those treated with selective serotonin reuptake inhibitor-type antidepressants. | Romero-Sanchiz P et al. | β | 2019 | β |
| Potential of Cannabinoid Receptor Ligands as Treatment for Substance Use Disorders. | Galaj E et al. | β | 2019 | β |
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| Real life Experience of Medical Cannabis Treatment in Autism: Analysis of Safety and Efficacy. | Bar-Lev Schleider L et al. | β | 2019 | β |
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| Roles of the Hepatic Endocannabinoid and Apelin Systems in the Pathogenesis of Liver Fibrosis. | Melgar-Lesmes P et al. | β | 2019 | β |
| Tempering aversive/traumatic memories with cannabinoids: a review of evidence from animal and human studies. | Lisboa SF et al. | β | 2019 | β |
| The Acute Activation of the CB1 Receptor in the Hippocampus Decreases Neurotoxicity and Prevents Spatial Memory Impairment in Rats Lesioned with Ξ²-Amyloid 25-35. | Patricio-MartΓnez A et al. | β | 2019 | β |
| The Endocannabinoid System in Pediatric Inflammatory and Immune Diseases. | Argenziano M et al. | β | 2019 | β |
| The motivation for exercise over palatable food is dictated by cannabinoid type-1 receptors. | Muguruza C et al. | β | 2019 | β |
| Therapeutic potential of cannabinoids as neuroprotective agents for damaged cells conducing to movement disorders. | Antonazzo M et al. | β | 2019 | β |
| Trans-cinnamaldehyde shows anti-depression effect in the forced swimming test and possible involvement of the endocannabinoid system. | Lin J et al. | β | 2019 | β |
| Unidirectional opioid-cannabinoid cross-tolerance in the modulation of social play behavior in rats. | Schiavi S et al. | β | 2019 | β |
| Astroglial CB<sub>1</sub> Receptors Determine Synaptic D-Serine Availability to Enable Recognition Memory. | Robin LM et al. | β | 2018 | β |
| Cannabidiol effects on prepulse inhibition in nonhuman primates. | Saletti PG et al. | β | 2018 | β |
| Cannabinoid disruption of learning mechanisms involved in reward processing. | Lupica CR et al. | β | 2018 | β |
| Cannabinoids and glial cells: possible mechanism to understand schizophrenia. | de Almeida V et al. | β | 2018 | β |
| Cannabinoids in health and disease: pharmacological potential in metabolic syndrome and neuroinflammation. | Mastinu A et al. | β | 2018 | β |
| Cannabis use during pregnancy: Pharmacokinetics and effects on child development. | Grant KS et al. | β | 2018 | β |
| CB1R-Mediated Activation of Caspase-3 Causes Epigenetic and Neurobehavioral Abnormalities in Postnatal Ethanol-Exposed Mice. | Subbanna S et al. | β | 2018 | β |
| CB<sub>1</sub> Receptor Signaling in the Brain: Extracting Specificity from Ubiquity. | Busquets-Garcia A et al. | β | 2018 | β |
| Chronic, intermittent treatment with a cannabinoid receptor agonist impairs recognition memory and brain network functional connectivity. | Mouro FM et al. | β | 2018 | β |
| Connexin 43 Hemichannel Activity Promoted by Pro-Inflammatory Cytokines and High Glucose Alters Endothelial Cell Function. | SΓ‘ez JC et al. | β | 2018 | β |
| Controlled-Deactivation CB1 Receptor Ligands as a Novel Strategy to Lower Intraocular Pressure. | Miller S et al. | β | 2018 | β |
| Cross-talk of cannabinoid and endocannabinoid metabolism is mediated via human cardiac CYP2J2. | Arnold WR et al. | β | 2018 | β |
| Current evidence of cannabinoid-based analgesia obtained in preclinical and human experimental settings. | LΓΆtsch J et al. | β | 2018 | β |
| Effects of an early life experience on rat brain cannabinoid receptors in adolescence and adulthood. | Vangopoulou C et al. | β | 2018 | β |
| Endocannabinoid and nitric oxide systems of the hypothalamic paraventricular nucleus mediate effects of NPY on energy expenditure. | PΓ©terfi Z et al. | β | 2018 | β |
| Examination of the effects of cannabinoid ligands on decision making in a rat gambling task. | Ferland JN et al. | β | 2018 | β |
| Expression and localization of CB1R, NAPE-PLD, and FAAH in the vervet monkey nucleus accumbens. | Kucera R et al. | β | 2018 | β |
| Extrasynaptic Neurotransmission Mediated by Exocytosis and Diffusive Release of Transmitter Substances. | Del-Bel E et al. | β | 2018 | β |
| Fever and hypothermia in systemic inflammation. | Garami A et al. | β | 2018 | β |
| Glutamatergic, GABAergic, and endocannabinoid neurotransmissions within the dorsal hippocampus modulate the cardiac baroreflex function in rats. | Ferreira-Junior NC et al. | β | 2018 | β |
| High Fat Diet Increases Circulating Endocannabinoids Accompanied by Increased Synthesis Enzymes in Adipose Tissue. | Kuipers EN et al. | β | 2018 | β |
| Hippocampal CB<sub>1</sub> Receptors Control Incidental Associations. | Busquets-Garcia A et al. | β | 2018 | β |
| Identification of Bivalent Ligands with Melatonin Receptor Agonist and Fatty Acid Amide Hydrolase (FAAH) Inhibitory Activity That Exhibit Ocular Hypotensive Effect in the Rabbit. | Spadoni G et al. | β | 2018 | β |
| Impact of maternal western diet-induced obesity on offspring mortality and peripheral endocannabinoid system in mice. | Perez PA et al. | β | 2018 | β |
| Inhibition of Diacylglycerol Lipase Impairs Fear Extinction in Mice. | Cavener VS et al. | β | 2018 | β |
| Lipidome Evolution in Mammalian Tissues. | Khrameeva E et al. | β | 2018 | β |
| Localization of the cannabinoid type-1 receptor in subcellular astrocyte compartments of mutant mouse hippocampus. | GutiΓ©rrez-RodrΓguez A et al. | β | 2018 | β |
| Medial prefrontal cortex TRPV1 and CB1 receptors modulate cardiac baroreflex activity by regulating the NMDA receptor/nitric oxide pathway. | Lagatta DC et al. | β | 2018 | β |
| Neuroprotective Effects of MAGL (Monoacylglycerol Lipase) Inhibitors in Experimental Ischemic Stroke. | Choi SH et al. | β | 2018 | β |
| New Perspectives on the Use of Cannabis in the Treatment of Psychiatric Disorders. | Scherma M et al. | β | 2018 | β |
| N-Phenylquinazolin-2-amine Yhhu4952 as a novel promotor for oligodendrocyte differentiation and myelination. | Yu X et al. | β | 2018 | β |
| Overlapping Distribution of Orexin and Endocannabinoid Receptors and Their Functional Interaction in the Brain of Adult Zebrafish. | Imperatore R et al. | β | 2018 | β |
| Oxytocin functions as a spatiotemporal filter for excitatory synaptic inputs to VTA dopamine neurons. | Xiao L et al. | β | 2018 | β |
| PAK1 regulates inhibitory synaptic function via a novel mechanism mediated by endocannabinoids. | Xia S et al. | β | 2018 | β |
| Proteomics and Lipidomics in the Elucidation of Endocannabinoid Signaling in Healthy and Schizophrenia Brains. | Seabra G et al. | β | 2018 | β |
| Role of the endocannabinoid system in drug addiction. | Manzanares J et al. | β | 2018 | β |
| Selective effects of Ξ9-tetrahydrocannabinol on medium spiny neurons in the striatum. | FernΓ‘ndez-Cabrera MR et al. | β | 2018 | β |
| Signaling pathways to and from the hypophysial pars tuberalis, an important center for the control of seasonal rhythms. | Korf HW | β | 2018 | β |
| Some Prospective Alternatives for Treating Pain: The Endocannabinoid System and Its Putative Receptors GPR18 and GPR55. | Guerrero-Alba R et al. | β | 2018 | β |
| Synthesis, Pharmacological Evaluation, and Docking Studies of Novel Pyridazinone-Based Cannabinoid Receptor Typeβ 2 Ligands. | Ragusa G et al. | β | 2018 | β |
| The Chemistry and Pharmacology of Synthetic Cannabinoid Receptor Agonists as New Psychoactive Substances: Origins. | Banister SD et al. | β | 2018 | β |
| The Endogenous Cannabinoid System: A Budding Source of Targets for Treating Inflammatory and Neuropathic Pain. | Donvito G et al. | β | 2018 | β |
| The Neuroglial Dialog Between Cannabinoids and Hemichannels. | Labra VC et al. | β | 2018 | β |
| The Role of the Endocannabinoid System and Genetic Variation in Adolescent Brain Development. | Meyer HC et al. | β | 2018 | β |
| The special relationship: glia-neuron interactions in the neuroendocrine hypothalamus. | Clasadonte J et al. | β | 2018 | β |
| Verbal Memory Performance and Reduced Cortical Thickness of Brain Regions Along the Uncinate Fasciculus in Young Adult Cannabis Users. | Levar N et al. | β | 2018 | β |
| Ξ9-Tetrahydrocannabinol and Cannabidiol Differentially Regulate Intraocular Pressure. | Miller S et al. | β | 2018 | β |
| 2-Arachidonoylglycerol endocannabinoid signaling coupled to metabotropic glutamate receptor type-5 modulates anxiety-like behavior in the rat ventromedial prefrontal cortex. | Almeida-Santos AF et al. | β | 2017 | β |
| Age-dependent plasticity in endocannabinoid modulation of pain processing through postnatal development. | Kwok CH et al. | β | 2017 | β |
| A GPR119 Signaling System in the Murine Eye Regulates Intraocular Pressure in a Sex-Dependent Manner. | Miller S et al. | β | 2017 | β |
| Alterations in Rat Accumbens Endocannabinoid and GABA Content during Fentanyl Treatment: The Role of Ghrelin. | Sustkova-Fiserova M et al. | β | 2017 | β |
| Anandamide exerts a suppressive effect on sperm binding to oviduct explants through CB1 receptors in the water buffalo (Bubalus bubalis). | Kumar V et al. | β | 2017 | β |
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| Building smart cannabis policy from the science up. | Weiss SRB et al. | β | 2017 | β |
| Cannabidiol Is a Potential Therapeutic for the Affective-Motivational Dimension of Incision Pain in Rats. | Genaro K et al. | β | 2017 | β |
| Cannabinoid Receptor Signaling in Central Regulation of Feeding Behavior: A Mini-Review. | Koch M | β | 2017 | β |
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| Cannabinoids in Parkinson's Disease. | Stampanoni Bassi M et al. | β | 2017 | β |
| Cannabinoids prevent the amyloid Ξ²-induced activation of astroglial hemichannels: A neuroprotective mechanism. | Gajardo-GΓ³mez R et al. | β | 2017 | β |
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| Circulating levels of endocannabinoids respond acutely to voluntary exercise, are altered in mice selectively bred for high voluntary wheel running, and differ between the sexes. | Thompson Z et al. | β | 2017 | β |
| Do Cannabinoids Confer Neuroprotection Against Epilepsy? An Overview. | Capasso A | β | 2017 | β |
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| Effects of JWH015 in cytokine secretion in primary human keratinocytes and fibroblasts and its suitability for topical/transdermal delivery. | Bort A et al. | β | 2017 | β |
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| Endocannabinoids exert CB<sub>1</sub> receptor-mediated neuroprotective effects in models of neuronal damage induced by HIV-1 Tat protein. | Xu C et al. | β | 2017 | β |
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| Focus on cannabinoids and synthetic cannabinoids. | Le Boisselier R et al. | β | 2017 | β |
| Functional Analysis of Mitochondrial CB1 Cannabinoid Receptors (mtCB1) in the Brain. | Melser S et al. | β | 2017 | β |
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| Identification of an endocannabinoid system in the rat pars tuberalis-a possible interface in the hypothalamic-pituitary-adrenal system? | Jafarpour A et al. | β | 2017 | β |
| Interactions between the Kynurenine and the Endocannabinoid System with Special Emphasis on Migraine. | Nagy-GrΓ³cz G et al. | β | 2017 | β |
| Interferon-Ξ³ causes mood abnormalities by altering cannabinoid CB1 receptor function in the mouse striatum. | Mandolesi G et al. | β | 2017 | β |
| Investigation of changes in endocannabinoids and N-acylethanolamides in biofluids, and their correlations with female infertility. | Ding J et al. | β | 2017 | β |
| Lipids in psychiatric disorders and preventive medicine. | Schneider M et al. | β | 2017 | β |
| Marijuana and other cannabinoids as a treatment for posttraumatic stress disorder: A literature review. | Steenkamp MM et al. | β | 2017 | β |
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| Membrane-mediated action of the endocannabinoid anandamide on membrane proteins: implications for understanding the receptor-independent mechanism. | Medeiros D et al. | β | 2017 | β |
| Microbes, Immunity, and Behavior: Psychoneuroimmunology Meets the Microbiome. | Dinan TG et al. | β | 2017 | β |
| Mitochondria Bioenergetic and Cognitive Functions: The Cannabinoid Link. | Mancini G et al. | β | 2017 | β |
| Molecular Dynamics Methodologies for Probing Cannabinoid Ligand/Receptor Interaction. | Lynch DL et al. | β | 2017 | β |
| N-arachidonoyl-serotonin, a dual FAAH and TRPV1 blocker, inhibits the retrieval of contextual fear memory: Role of the cannabinoid CB1 receptor in the dorsal hippocampus. | Gobira PH et al. | β | 2017 | β |
| Perspectives of Cannabinoid Type 2 Receptor (CB2R) Ligands in Neurodegenerative Disorders: Structure-Affinity Relationship (SAfiR) and Structure-Activity Relationship (SAR) Studies. | Spinelli F et al. | β | 2017 | β |
| Pharmacological inhibition of FAAH activity in rodents: A promising pharmacological approach for psychological-cardiac comorbidity? | Carnevali L et al. | β | 2017 | β |
| Pros and Cons of Medical Cannabis use by People with Chronic Brain Disorders. | Suryadevara U et al. | β | 2017 | β |
| Radiosynthesis and evaluation of new PET ligands for peripheral cannabinoid receptor type 1 imaging. | Yamasaki T et al. | β | 2017 | β |
| Selectively Impaired Endocannabinoid-Dependent Long-Term Depression in the Lateral Habenula in an Animal Model of Depression. | Park H et al. | β | 2017 | β |
| Spicing Up Pharmacology: A Review of Synthetic Cannabinoids From Structure to Adverse Events. | Davidson C et al. | β | 2017 | β |
| Synaptic functions of endocannabinoid signaling in health and disease. | Araque A et al. | β | 2017 | β |
| Synthesis and Preliminary Biological Evaluation of Indol-3-yl-oxoacetamides as Potent Cannabinoid Receptor Type 2 Ligands. | Moldovan RP et al. | β | 2017 | β |
| The Cannabinoid Receptor Interacting Proteins 1 of zebrafish are not required for morphological development, viability or fertility. | Fin L et al. | β | 2017 | β |
| The CB1 Receptor as the Cornerstone of Exostasis. | Piazza PV et al. | β | 2017 | β |
| The endocannabinoid system, a novel and key participant in acupuncture's multiple beneficial effects. | Hu B et al. | β | 2017 | β |
| The endocannabinoid system expression in the female reproductive tract is modulated by estrogen. | Maia J et al. | β | 2017 | β |
| The Epac-Phospholipase CΞ΅ Pathway Regulates Endocannabinoid Signaling and Cocaine-Induced Disinhibition of Ventral Tegmental Area Dopamine Neurons. | Tong J et al. | β | 2017 | β |
| The potential role of cannabinoids in epilepsy treatment. | De Caro C et al. | β | 2017 | β |
| The therapeutic potential of the phytocannabinoid cannabidiol for Alzheimer's disease. | Karl T et al. | β | 2017 | β |
| Actions of the dual FAAH/MAGL inhibitor JZL195 in a murine neuropathic pain model. | Adamson Barnes NS et al. | β | 2016 | β |
| Activation of endocannabinoid system in the rat basolateral amygdala improved scopolamine-induced memory consolidation impairment. | Nedaei SE et al. | β | 2016 | β |
| Anxiety-like responses induced by nitric oxide within the BNST in mice: Role of CRF1 and NMDA receptors. | Faria MP et al. | β | 2016 | β |
| Are the endocannabinoid-like compounds N-acyl aminoacids neuroprotective after traumatic brain injury? | Mann A et al. | β | 2016 | β |
| Astroglial type-1 cannabinoid receptor (CB1): A new player in the tripartite synapse. | Oliveira da Cruz JF et al. | β | 2016 | β |
| Bile Acid Recognition by NAPE-PLD. | Margheritis E et al. | β | 2016 | β |
| Brain Mapping-Based Model of Ξ(9)-Tetrahydrocannabinol Effects on Connectivity in the Pain Matrix. | Walter C et al. | β | 2016 | β |
| Cannabinoid CB<sub>1</sub> Receptors Are Localized in Striated Muscle Mitochondria and Regulate Mitochondrial Respiration. | Mendizabal-Zubiaga J et al. | β | 2016 | β |
| Cannabinoid receptor signaling induces proliferation but not neurogenesis in the mouse olfactory epithelium. | Hutch CR et al. | β | 2016 | β |
| Cannabinoids and post-traumatic stress disorder: clinical and preclinical evidence for treatment and prevention. | Mizrachi Zer-Aviv T et al. | β | 2016 | β |
| Cellular and System Biology of Memory: Timing, Molecules, and Beyond. | Korte M et al. | β | 2016 | β |
| Cocaine-induced behavioral sensitization decreases the expression of endocannabinoid signaling-related proteins in the mouse hippocampus. | Blanco E et al. | β | 2016 | β |
| Controlled downregulation of the cannabinoid CB1 receptor provides a promising approach for the treatment of obesity and obesity-derived type 2 diabetes. | Lu D et al. | β | 2016 | β |
| Critical needs in drug discovery for cessation of alcohol and nicotine polysubstance abuse. | Van Skike CE et al. | β | 2016 | β |
| Detection and qualitative analysis of fatty acid amides in the urine of alcoholics using HPLC-QTOF-MS. | Dabur R et al. | β | 2016 | β |
| Dissecting the Signaling Pathways Involved in the Crosstalk between Metabotropic Glutamate 5 and Cannabinoid Type 1 Receptors. | Olmo IG et al. | β | 2016 | β |
| Drug-Induced Alterations of Endocannabinoid-Mediated Plasticity in Brain Reward Regions. | Zlebnik NE et al. | β | 2016 | β |
| Emotional arousal state influences the ability of amygdalar endocannabinoid signaling to modulate anxiety. | Morena M et al. | β | 2016 | β |
| Endocannabinoid 2-AG and intracellular cannabinoid receptors modulate a low-threshold calcium spike-induced slow depolarizing afterpotential in rat thalamic paraventricular nucleus neurons. | Zhang L et al. | β | 2016 | β |
| Endocannabinoid dynamics gate spike-timing dependent depression and potentiation. | Cui Y et al. | β | 2016 | β |
| Endocannabinoid Modulation of Predator Stress-Induced Long-Term Anxiety in Rats. | Lim J et al. | β | 2016 | β |
| Endocannabinoids and Heterogeneity of Glial Cells in Brain Function. | Scheller A et al. | β | 2016 | β |
| Endocannabinoid signaling enhances visual responses through modulation of intracellular chloride levels in retinal ganglion cells. | Miraucourt LS et al. | β | 2016 | β |
| Endogenous cannabinoid system alterations and their role in epileptogenesis after brain injury in rat. | Wang X et al. | β | 2016 | β |
| Enhancement of Anandamide-Mediated Endocannabinoid Signaling Corrects Autism-Related Social Impairment. | Wei D et al. | β | 2016 | β |
| Estrogen Receptor Beta and 2-arachidonoylglycerol Mediate the Suppressive Effects of Estradiol on Frequency of Postsynaptic Currents in Gonadotropin-Releasing Hormone Neurons of Metestrous Mice: An Acute Slice Electrophysiological Study. | BΓ‘lint F et al. | β | 2016 | β |
| Evidence for a GPR18 Role in Diurnal Regulation of Intraocular Pressure. | Miller S et al. | β | 2016 | β |
| Examination of the Addictive and Behavioral Properties of Fatty Acid-Binding Protein Inhibitor SBFI26. | Thanos PK et al. | β | 2016 | β |
| Excess cerebral TNF causing glutamate excitotoxicity rationalizes treatment of neurodegenerative diseases and neurogenic pain by anti-TNF agents. | Clark IA et al. | β | 2016 | β |
| Expression and Function of the Endocannabinoid System in the Retina and the Visual Brain. | Bouchard JF et al. | β | 2016 | β |
| Ghrelin and endocannabinoids participation in morphine-induced effects in the rat nucleus accumbens. | Sustkova-Fiserova M et al. | β | 2016 | β |
| Glial Modulation by N-acylethanolamides in Brain Injury and Neurodegeneration. | Herrera MI et al. | β | 2016 | β |
| Harnessing the Endocannabinoid 2-Arachidonoylglycerol to Lower Intraocular Pressure in a Murine Model. | Miller S et al. | β | 2016 | β |
| Hydrophobic Ligand Entry and Exit Pathways of the CB1 Cannabinoid Receptor. | Jakowiecki J et al. | β | 2016 | β |
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| Interactions between the endocannabinoid and nicotinic cholinergic systems: preclinical evidence and therapeutic perspectives. | Scherma M et al. | β | 2016 | β |
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| Marijuana Compounds: A Nonconventional Approach to Parkinson's Disease Therapy. | Babayeva M et al. | β | 2016 | β |
| Mechanical and material properties of cortical and trabecular bone from cannabinoid receptor-1-null (Cnr1(-/-)) mice. | Khalid AB et al. | β | 2016 | β |
| Medicinal Chemistry, Pharmacology, and Potential Therapeutic Benefits of Cannabinoid CB2 Receptor Agonists. | Aghazadeh Tabrizi M et al. | β | 2016 | β |
| MicroRNA let-7d is a target of cannabinoid CB1 receptor and controls cannabinoid signaling. | Chiarlone A et al. | β | 2016 | β |
| Minocycline Attenuates Neonatal Germinal-Matrix-Hemorrhage-Induced Neuroinflammation and Brain Edema by Activating Cannabinoid Receptor 2. | Tang J et al. | β | 2016 | β |
| Modulation of cannabinoid signaling by hippocampal 5-HT4 serotonergic system in fear conditioning. | Nasehi M et al. | β | 2016 | β |
| Molecular Mechanisms of Cannabis Signaling in the Brain. | Ronan PJ et al. | β | 2016 | β |
| N-(3,4-Dimethylisoxazol-5-yl)piperazine-4-[4-(2-fluoro-4-[(11)C]methylphenyl)thiazol-2-yl]-1-carboxamide: A promising positron emission tomography ligand for fatty acid amide hydrolase. | Shimoda Y et al. | β | 2016 | β |
| Neuronal and Astrocytic Monoacylglycerol Lipase Limit the Spread of Endocannabinoid Signaling in the Cerebellum. | Chen Y et al. | β | 2016 | β |
| Neuroprotective Effect Is Driven Through the Upregulation of CB1 Receptor in Experimental Autoimmune Encephalomyelitis. | Lou ZY et al. | β | 2016 | β |
| Optimized extraction of 2-arachidonyl glycerol and anandamide from aortic tissue and plasma for quantification by LC-MS/MS. | Garst C et al. | β | 2016 | β |
| p21-activated kinase 1 restricts tonic endocannabinoid signaling in the hippocampus. | Xia S et al. | β | 2016 | β |
| Piperidinyl thiazole isoxazolines: A new series of highly potent, slowly reversible FAAH inhibitors with analgesic properties. | Pember SO et al. | β | 2016 | β |
| Preclinical studies on the reinforcing effects of cannabinoids. A tribute to the scientific research of Dr. Steve Goldberg. | Tanda G | β | 2016 | β |
| Repeated administration of a synthetic cannabinoid receptor agonist differentially affects cortical and accumbal neuronal morphology in adolescent and adult rats. | Carvalho AF et al. | β | 2016 | β |
| Role of the basolateral amygdala dopamine receptors in arachidonylcyclopropylamide-induced fear learning deficits. | Nasehi M et al. | β | 2016 | β |
| Roles for the endocannabinoid system in ethanol-motivated behavior. | Henderson-Redmond AN et al. | β | 2016 | β |
| Synthesis and Preliminary PET Imaging Studies of a FAAH Radiotracer ([ΒΉΒΉC]MPPO) Based on Ξ±-Ketoheterocyclic Scaffold. | Wang L et al. | β | 2016 | β |
| Synthesis, Biodistribution and <i>In vitro</i> Evaluation of Brain Permeable High Affinity Type 2 Cannabinoid Receptor Agonists [<sup>11</sup>C]MA2 and [<sup>18</sup>F]MA3. | Ahamed M et al. | β | 2016 | β |
| Targeting anandamide metabolism rescues core and associated autistic-like symptoms in rats prenatally exposed to valproic acid. | Servadio M et al. | β | 2016 | β |
| THC and endocannabinoids differentially regulate neuronal activity in the prefrontal cortex and hippocampus in the subchronic PCP model of schizophrenia. | Aguilar DD et al. | β | 2016 | β |
| The Impact of Marijuana Use on Memory in HIV-Infected Patients: A Comprehensive Review of the HIV and Marijuana Literatures. | Skalski LM et al. | β | 2016 | β |
| The neurobiology of social play and its rewarding value in rats. | Vanderschuren LJ et al. | β | 2016 | β |
| Tightrope or Slackline? The Neuroscience of Psychoactive Substances. | Coulon P et al. | β | 2016 | β |
| Traditional marijuana, high-potency cannabis and synthetic cannabinoids: increasing risk for psychosis. | Murray RM et al. | β | 2016 | β |
| Triglyceride sensing in the reward circuitry: A new insight in feeding behaviour regulation. | Cansell C et al. | β | 2016 | β |
| URB597 inhibits oxidative stress induced by alcohol binging in the prefrontal cortex of adolescent rats. | PeliΓ§Γ£o R et al. | β | 2016 | β |
| A cannabinoid receptor 1 polymorphism is protective against major depressive disorder in methadone-maintained outpatients. | Icick R et al. | β | 2015 | β |
| Active endocannabinoids are secreted on extracellular membrane vesicles. | Gabrielli M et al. | β | 2015 | β |
| Analysis in conditional cannabinoid 1 receptor-knockout mice reveals neuronal subpopulation-specific effects on epileptogenesis in the kindling paradigm. | von RΓΌden EL et al. | β | 2015 | β |
| Anandamide hydrolysis in FAAH reveals a dual strategy for efficient enzyme-assisted amide bond cleavage via nitrogen inversion. | Palermo G et al. | β | 2015 | β |
| An animal model of female adolescent cannabinoid exposure elicits a long-lasting deficit in presynaptic long-term plasticity. | Lovelace JW et al. | β | 2015 | β |
| An endocannabinoid system is present in the mouse olfactory epithelium but does not modulate olfaction. | Hutch CR et al. | β | 2015 | β |
| Anti-aversive role of the endocannabinoid system in the periaqueductal gray stimulation model of panic attacks in rats. | Viana TG et al. | β | 2015 | β |
| A pivotal role for enhanced brainstem Orexin receptor 1 signaling in the central cannabinoid receptor 1-mediated pressor response in conscious rats. | Ibrahim BM et al. | β | 2015 | β |
| A quantitiative LC-MS/MS method for the measurement of arachidonic acid, prostanoids, endocannabinoids, N-acylethanolamines and steroids in human plasma. | Gachet MS et al. | β | 2015 | β |
| A robust capillary liquid chromatography/tandem mass spectrometry method for quantitation of neuromodulatory endocannabinoids. | Qi M et al. | β | 2015 | β |
| BDNF interacts with endocannabinoids to regulate cocaine-induced synaptic plasticity in mouse midbrain dopamine neurons. | Zhong P et al. | β | 2015 | β |
| Blockade of 2-arachidonoylglycerol hydrolysis produces antidepressant-like effects and enhances adult hippocampal neurogenesis and synaptic plasticity. | Zhang Z et al. | β | 2015 | β |
| Blunted cardiac response to hemorrhage in cirrhotic rats is mediated by local macrophage-released endocannabinoids. | Gaskari SA et al. | β | 2015 | β |
| Cannabidiol, a Cannabis sativa constituent, inhibits cocaine-induced seizures in mice: Possible role of the mTOR pathway and reduction in glutamate release. | Gobira PH et al. | β | 2015 | β |
| Cannabinoid CB1 receptors in the dorsal hippocampus and prelimbic medial prefrontal cortex modulate anxiety-like behavior in rats: additional evidence. | Lisboa SF et al. | β | 2015 | β |
| Cannabinoid-related olfactory neuroscience in mice and humans. | LΓΆtsch J et al. | β | 2015 | β |
| Cannabinoids and Epilepsy. | Rosenberg EC et al. | β | 2015 | β |
| CB1 and CB2 cannabinoid receptor antagonists prevent minocycline-induced neuroprotection following traumatic brain injury in mice. | Lopez-Rodriguez AB et al. | β | 2015 | β |
| Cellular Mechanisms of Action of Drug Abuse on Olfactory Neurons. | Heinbockel T et al. | β | 2015 | β |
| Cerebellar endocannabinoids: retrograde signaling from purkinje cells. | Marcaggi P | β | 2015 | β |
| Common single nucleotide variants underlying drug addiction: more than a decade of research. | BΓΌhler KM et al. | β | 2015 | β |
| Computational insights into function and inhibition of fatty acid amide hydrolase. | Palermo G et al. | β | 2015 | β |
| Development of [(11)C]MFTC for PET imaging of fatty acid amide hydrolase in rat and monkey brains. | Kumata K et al. | β | 2015 | β |
| Dissecting the cannabinergic control of behavior: The where matters. | Busquets-Garcia A et al. | β | 2015 | β |
| Distinct roles of the endocannabinoids anandamide and 2-arachidonoylglycerol in social behavior and emotionality at different developmental ages in rats. | Manduca A et al. | β | 2015 | β |
| Embedded synaptic feedback in the neuroendocrine stress axis. | Wamsteeker Cusulin JI et al. | β | 2015 | β |
| Endocannabinoid and ceramide levels are altered in patients with colorectal cancer. | Chen L et al. | β | 2015 | β |
| Endocannabinoids and striatal function: implications for addiction-related behaviours. | Moreira FA et al. | β | 2015 | β |
| Endocannabinoids Induce Lateral Long-Term Potentiation of Transmitter Release by Stimulation of Gliotransmission. | GΓ³mez-Gonzalo M et al. | β | 2015 | β |
| Endocannabinoid system activation may be associated with insulin resistance in women with polycystic ovary syndrome. | Juan CC et al. | β | 2015 | β |
| Endocannabinoid transport revisited. | Nicolussi S et al. | β | 2015 | β |
| Endogenous vs Exogenous Allosteric Modulators in GPCRs: A dispute for shuttling CB1 among different membrane microenvironments. | Stornaiuolo M et al. | β | 2015 | β |
| Enhancement of endocannabinoid signaling protects against cocaine-induced neurotoxicity. | Vilela LR et al. | β | 2015 | β |
| Fatty acid amide hydrolase inhibitors: a patent review (2009-2014). | Lodola A et al. | β | 2015 | β |
| Fetal Alcohol Spectrum Disorder: Potential Role of Endocannabinoids Signaling. | Basavarajappa BS | β | 2015 | β |
| Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture. | Malenczyk K et al. | β | 2015 | β |
| G protein-coupled receptors in stem cell maintenance and somatic reprogramming to pluripotent or cancer stem cells. | Choi HY et al. | β | 2015 | β |
| Habenular CB1 Receptors Control the Expression of Aversive Memories. | Soria-GΓ³mez E et al. | β | 2015 | β |
| Increased Contextual Fear Conditioning in iNOS Knockout Mice: Additional Evidence for the Involvement of Nitric Oxide in Stress-Related Disorders and Contribution of the Endocannabinoid System. | Lisboa SF et al. | β | 2015 | β |
| Increased tonic cannabinoid CB1R activity and brain region-specific desensitization of CB1R Gi/o signaling axis in mice with global genetic knockout of monoacylglycerol lipase. | Navia-Paldanius D et al. | β | 2015 | β |
| Inhibiting endocannabinoid biosynthesis: a novel approach to the treatment of constipation. | Bashashati M et al. | β | 2015 | β |
| Involvement of 2-arachidonoylglycerol signaling in social challenge responding of male CD1 mice. | Aliczki M et al. | β | 2015 | β |
| Leptin and the brain: influences on brain development, cognitive functioning and psychiatric disorders. | Farr OM et al. | β | 2015 | β |
| Modulation of the effects of the cannabinoid agonist, ACPA, on spatial and non-spatial novelty detection in mice by dopamine D1 receptor drugs infused into the basolateral amygdala. | Mohammadi M et al. | β | 2015 | β |
| Monoacylglycerol lipase (MGLL) polymorphism rs604300 interacts with childhood adversity to predict cannabis dependence symptoms and amygdala habituation: Evidence from an endocannabinoid system-level analysis. | Carey CE et al. | β | 2015 | β |
| Neural Plasticity in Multiple Sclerosis: The Functional and Molecular Background. | Ksiazek-Winiarek DJ et al. | β | 2015 | β |
| Neuropsychological sex differences associated with age of initiated use among young adult cannabis users. | Crane NA et al. | β | 2015 | β |
| Nuclear diacylglycerol lipase-Ξ± in rat brain cortical neurons: evidence of 2-arachidonoylglycerol production in concert with phospholipase C-Ξ² activity. | GarcΓa del CaΓ±o G et al. | β | 2015 | β |
| On the effects of CP 55-940 and other cannabinoid receptor agonists in C6 and U373 cell lines. | Ortega A et al. | β | 2015 | β |
| Opposite control of frontocortical 2-arachidonoylglycerol turnover rate by cannabinoid type-1 receptors located on glutamatergic neurons and on astrocytes. | Belluomo I et al. | β | 2015 | β |
| Part II: Strain- and sex-specific effects of adolescent exposure to THC on adult brain and behaviour: Variants of learning, anxiety and volumetric estimates. | Keeley RJ et al. | β | 2015 | β |
| Peripheral FAAH and soluble epoxide hydrolase inhibitors are synergistically antinociceptive. | Sasso O et al. | β | 2015 | β |
| Potential Therapeutical Contributions of the Endocannabinoid System towards Aging and Alzheimer's Disease. | Bonnet AE et al. | β | 2015 | β |
| Potential Therapeutic Value of a Novel FAAH Inhibitor for the Treatment of Anxiety. | Marco EM et al. | β | 2015 | β |
| Regulation of neuronal communication by G protein-coupled receptors. | Huang Y et al. | β | 2015 | β |
| Rhythmic control of endocannabinoids in the rat pineal gland. | Koch M et al. | β | 2015 | β |
| Rising stars: modulation of brain functions by astroglial type-1 cannabinoid receptors. | Metna-Laurent M et al. | β | 2015 | β |
| Role of the endogenous cannabinoid system in nicotine addiction: novel insights. | Gamaleddin IH et al. | β | 2015 | β |
| Safety and Toxicology of Cannabinoids. | Sachs J et al. | β | 2015 | β |
| Soluble epoxide hydrolase inhibitory activity of anthraquinone components from Aloe. | Sun YN et al. | β | 2015 | β |
| The Antitumor Activity of Plant-Derived Non-Psychoactive Cannabinoids. | McAllister SD et al. | β | 2015 | β |
| The cannabinoid system in the retrosplenial cortex modulates fear memory consolidation, reconsolidation, and extinction. | Sachser RM et al. | β | 2015 | β |
| The CBβ cannabinoid receptor signals striatal neuroprotection via a PI3K/Akt/mTORC1/BDNF pathway. | BlΓ‘zquez C et al. | β | 2015 | β |
| The endocannabinoid, endovanilloid and nitrergic systems could interact in the rat dorsolateral periaqueductal gray matter to control anxiety-like behaviors. | Batista PA et al. | β | 2015 | β |
| The Endocannabinoid System and Its Role in Regulating the Intrinsic Neural Circuitry of the Gastrointestinal Tract. | Trautmann SM et al. | β | 2015 | β |
| The endocannabinoid system within the dorsal lateral geniculate nucleus of the vervet monkey. | Javadi P et al. | β | 2015 | β |
| The interplay between inflammatory cytokines and the endocannabinoid system in the regulation of synaptic transmission. | Rossi S et al. | β | 2015 | β |
| Ultrastructural evidence for synaptic contacts between cortical noradrenergic afferents and endocannabinoid-synthesizing post-synaptic neurons. | Reyes BA et al. | β | 2015 | β |
| Actions of the dual FAAH/MAGL inhibitor JZL195 in a murine inflammatory pain model. | Anderson WB et al. | β | 2014 | β |
| Advances in the discovery of N-acylethanolamine acid amidase inhibitors. | Bandiera T et al. | β | 2014 | β |
| A mighty (ochondrial) fight? | Piomelli D | β | 2014 | β |
| Anandamide activation of CB1 receptors increases spontaneous bursting and oscillatory activity in the thalamus. | Dasilva M et al. | β | 2014 | β |
| Angiotensin II-induced activation of central AT1 receptors exerts endocannabinoid-mediated gastroprotective effect in rats. | Gyires K et al. | β | 2014 | β |
| A restricted population of CB1 cannabinoid receptors with neuroprotective activity. | Chiarlone A et al. | β | 2014 | β |
| A role for the endocannabinoid system in exercise-induced spatial memory enhancement in mice. | Ferreira-Vieira TH et al. | β | 2014 | β |
| Astrocytes in endocannabinoid signalling. | Navarrete M et al. | β | 2014 | β |
| A thermal window for yawning in humans: yawning as a brain cooling mechanism. | Massen JJ et al. | β | 2014 | β |
| Behavioral and electrophysiological effects of endocannabinoid and dopaminergic systems on salient stimuli. | Laricchiuta D et al. | β | 2014 | β |
| Beyond radio-displacement techniques for identification of CB1 ligands: the first application of a fluorescence-quenching assay. | Bruno A et al. | β | 2014 | β |
| Blunting of the HPA-axis underlies the lack of preventive efficacy of early post-stressor single-dose Delta-9-tetrahydrocannabinol (THC). | Mayer TA et al. | β | 2014 | β |
| Brain regional cannabinoid CB(1) receptor signalling and alternative enzymatic pathways for 2-arachidonoylglycerol generation in brain sections of diacylglycerol lipase deficient mice. | Aaltonen N et al. | β | 2014 | β |
| Cannabinoid 1 receptors in keratinocytes attenuate fluorescein isothiocyanate-induced mouse atopic-like dermatitis. | Gaffal E et al. | β | 2014 | β |
| Cannabinoid CB2 receptor (CB2R) stimulation delays rubrospinal mitochondrial-dependent degeneration and improves functional recovery after spinal cord hemisection by ERK1/2 inactivation. | Latini L et al. | β | 2014 | β |
| Cannabinoid control of brain bioenergetics: Exploring the subcellular localization of the CB1 receptor. | Hebert-Chatelain E et al. | β | 2014 | β |
| Cannabinoid-induced changes in respiration of brain mitochondria. | FiΕ‘ar Z et al. | β | 2014 | β |
| Cannabinoid receptor 1 signaling in cardiovascular regulating nuclei in the brainstem: A review. | Ibrahim BM et al. | β | 2014 | β |
| Cannabinoid receptor type 1 receptors on GABAergic vs. glutamatergic neurons differentially gate sex-dependent social interest in mice. | Terzian AL et al. | β | 2014 | β |
| Cannabinoid Regulation of Brain Reward Processing with an Emphasis on the Role of CB1 Receptors: A Step Back into the Future. | Panagis G et al. | β | 2014 | β |
| Cannabinoids for treatment of Alzheimer's disease: moving toward the clinic. | Aso E et al. | β | 2014 | β |
| Cannabinoid type-1 receptors in the paraventricular nucleus of the hypothalamus inhibit stimulated food intake. | Soria-GΓ³mez E et al. | β | 2014 | β |
| Changes in endocannabinoid and N-acylethanolamine levels in rat brain structures following cocaine self-administration and extinction training. | Bystrowska B et al. | β | 2014 | β |
| Cocaine-induced behavioral sensitization is associated with changes in the expression of endocannabinoid and glutamatergic signaling systems in the mouse prefrontal cortex. | Blanco E et al. | β | 2014 | β |
| Consequences of early life stress on the expression of endocannabinoid-related genes in the rat brain. | Marco EM et al. | β | 2014 | β |
| Control of synaptic function by endocannabinoid-mediated retrograde signaling. | Kano M | β | 2014 | β |
| Distance measurements and conformational analysis of sn-2-arachidonoylglycerol-membrane sample by Β²H-Β³ΒΉP REDOR NMR. | Tiburu EK et al. | β | 2014 | β |
| Effects of acute versus repeated cocaine exposure on the expression of endocannabinoid signaling-related proteins in the mouse cerebellum. | Palomino A et al. | β | 2014 | β |
| Effects of cannabinoid and vanilloid drugs on positive and negative-like symptoms on an animal model of schizophrenia: the SHR strain. | Almeida V et al. | β | 2014 | β |
| Elevation of endogenous anandamide impairs LTP, learning, and memory through CB1 receptor signaling in mice. | Basavarajappa BS et al. | β | 2014 | β |
| Endocannabinoid-dependent modulation of phasic dopamine signaling encodes external and internal reward-predictive cues. | Wenzel JM et al. | β | 2014 | β |
| Endocannabinoids are Involved in Male Vertebrate Reproduction: Regulatory Mechanisms at Central and Gonadal Level. | Bovolin P et al. | β | 2014 | β |
| Endocannabinoid signalling in neuronal migration. | Zhou Y et al. | β | 2014 | β |
| Ethanol exposure induces neonatal neurodegeneration by enhancing CB1R Exon1 histone H4K8 acetylation and up-regulating CB1R function causing neurobehavioral abnormalities in adult mice. | Subbanna S et al. | β | 2014 | β |
| Exploring developmental and physiological functions of fatty acid and lipid variants through worm and fly genetics. | Zhu H et al. | β | 2014 | β |
| Genetic disruption of 2-arachidonoylglycerol synthesis reveals a key role for endocannabinoid signaling in anxiety modulation. | Shonesy BC et al. | β | 2014 | β |
| Identification of the major prostaglandin glycerol ester hydrolase in human cancer cells. | Manna JD et al. | β | 2014 | β |
| Immune system: a possible nexus between cannabinoids and psychosis. | SuΓ‘rez-Pinilla P et al. | β | 2014 | β |
| Impaired fear memory specificity associated with deficient endocannabinoid-dependent long-term plasticity. | Lovelace JW et al. | β | 2014 | β |
| Increasing endocannabinoid levels in the ventral pallidum restore aberrant dopamine neuron activity in the subchronic PCP rodent model of schizophrenia. | Aguilar DD et al. | β | 2014 | β |
| Individual differences in response to positive and negative stimuli: endocannabinoid-based insight on approach and avoidance behaviors. | Laricchiuta D et al. | β | 2014 | β |
| Inhibition of endocannabinoid neuronal uptake and hydrolysis as strategies for developing anxiolytic drugs. | Batista LA et al. | β | 2014 | β |
| Interplay between synaptic endocannabinoid signaling and metaplasticity in neuronal circuit function and dysfunction. | Melis M et al. | β | 2014 | β |
| Is fat taste ready for primetime? | DiPatrizio NV | β | 2014 | β |
| Ligand activation of cannabinoid receptors attenuates hypertrophy of neonatal rat cardiomyocytes. | Lu Y et al. | β | 2014 | β |
| Long-term consequences of perinatal fatty acid amino hydrolase inhibition. | Wu CS et al. | β | 2014 | β |
| Low-frequency stimulation evokes serotonin release in the nucleus accumbens and induces long-term depression via production of endocannabinoid. | Burattini C et al. | β | 2014 | β |
| Marijuana use: neuroscience perspective. | Konopka LM | β | 2014 | β |
| Metabolism and disposition of MM-433593, a selective FAAH-1 inhibitor, in monkeys. | Banijamali AR et al. | β | 2014 | β |
| Modulation of defensive behavior by Transient Receptor Potential Vanilloid Type-1 (TRPV1) channels. | Aguiar DC et al. | β | 2014 | β |
| Modulation of T-type calcium channels by bioactive lipids. | Chemin J et al. | β | 2014 | β |
| Neuromodulators, stress and plasticity: a role for endocannabinoid signalling. | Senst L et al. | β | 2014 | β |
| New insights on food intake control by olfactory processes: the emerging role of the endocannabinoid system. | Soria-Gomez E et al. | β | 2014 | β |
| On the crucial cerebellar wound healing-related pathways and their cross-talks after traumatic brain injury in Danio rerio. | Wu CC et al. | β | 2014 | β |
| On the interaction between drugs of abuse and adolescent social behavior. | Trezza V et al. | β | 2014 | β |
| Peripheral cannabinoid 1 receptor blockade activates brown adipose tissue and diminishes dyslipidemia and obesity. | Boon MR et al. | β | 2014 | β |
| Peripheral interactions between cannabinoid and opioid systems contribute to the antinociceptive effect of crotalphine. | Machado FC et al. | β | 2014 | β |
| PET imaging of fatty acid amide hydrolase with [(18)F]DOPP in nonhuman primates. | Rotstein BH et al. | β | 2014 | β |
| Pharmacological activation of CB1 receptor modulates long term potentiation by interfering with protein synthesis. | Navakkode S et al. | β | 2014 | β |
| Pre- and postsynaptic type-1 cannabinoid receptors control the alterations of glutamate transmission in experimental autoimmune encephalomyelitis. | Musella A et al. | β | 2014 | β |
| Pregnenolone can protect the brain from cannabis intoxication. | VallΓ©e M et al. | β | 2014 | β |
| Prior stimulation of the endocannabinoid system prevents methamphetamine-induced dopaminergic neurotoxicity in the striatum through activation of CB2 receptors. | Nader J et al. | β | 2014 | β |
| Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies. | Maccarrone M et al. | β | 2014 | β |
| Regulation of nausea and vomiting by cannabinoids and the endocannabinoid system. | Sharkey KA et al. | β | 2014 | β |
| Role of the basolateral amygdala in mediating the effects of the fatty acid amide hydrolase inhibitor URB597 on HPA axis response to stress. | Bedse G et al. | β | 2014 | β |
| Shaping inhibition: activity dependent structural plasticity of GABAergic synapses. | Flores CE et al. | β | 2014 | β |
| Substrate-selective COX-2 inhibition as a novel strategy for therapeutic endocannabinoid augmentation. | Hermanson DJ et al. | β | 2014 | β |
| Systematic review of the literature on clinical and experimental trials on the antitumor effects of cannabinoids in gliomas. | Rocha FC et al. | β | 2014 | β |
| Systemic administration of oleoylethanolamide protects from neuroinflammation and anhedonia induced by LPS in rats. | Sayd A et al. | β | 2014 | β |
| The dual blocker of FAAH/TRPV1 N-arachidonoylserotonin reverses the behavioral despair induced by stress in rats and modulates the HPA-axis. | Navarria A et al. | β | 2014 | β |
| The endocannabinoid system and the neuroendocrine control of hydromineral balance. | Ruginsk SG et al. | β | 2014 | β |
| The endocannabinoid system controls food intake via olfactory processes. | Soria-GΓ³mez E et al. | β | 2014 | β |
| The influence of cannabinoids on generic traits of neurodegeneration. | Fagan SG et al. | β | 2014 | β |
| The systemic administration of oleoylethanolamide exerts neuroprotection of the nigrostriatal system in experimental Parkinsonism. | Gonzalez-Aparicio R et al. | β | 2014 | β |
| Translational strategies for therapeutic development in nicotine addiction: rethinking the conventional bench to bedside approach. | Le Foll B et al. | β | 2014 | β |
| Troubleshooting in LC-MS/MS method for determining endocannabinoid and endocannabinoid-like molecules in rat brain structures applied to assessing the brain endocannabinoid/endovanilloid system significance. | Bystrowska B et al. | β | 2014 | β |
| Ξ²-Caryophyllene ameliorates the Alzheimer-like phenotype in APP/PS1 Mice through CB2 receptor activation and the PPARΞ³ pathway. | Cheng Y et al. | β | 2014 | β |
| 2-arachidonoylglycerol interferes with lithium-induced vomiting in the house musk shrew, Suncus murinus. | Sticht MA et al. | β | 2013 | β |
| A binding site for nonsteroidal anti-inflammatory drugs in fatty acid amide hydrolase. | Bertolacci L et al. | β | 2013 | β |
| Acute inhibition of diacylglycerol lipase blocks endocannabinoid-mediated retrograde signalling: evidence for on-demand biosynthesis of 2-arachidonoylglycerol. | Hashimotodani Y et al. | β | 2013 | β |
| A fatty gut feeling. | Piomelli D | β | 2013 | β |
| Analgesic effect of a mixed T-type channel inhibitor/CB2 receptor agonist. | Gadotti VM et al. | β | 2013 | β |
| Anandamide-CB1 receptor signaling contributes to postnatal ethanol-induced neonatal neurodegeneration, adult synaptic, and memory deficits. | Subbanna S et al. | β | 2013 | β |
| Anandamide levels fluctuate in the bovine oviduct during the oestrous cycle. | Gervasi MG et al. | β | 2013 | β |
| A role for endocannabinoids in acute stress-induced suppression of the hypothalamic-pituitary-gonadal axis in male rats. | Karamikheirabad M et al. | β | 2013 | β |
| A role for O-1602 and G protein-coupled receptor GPR55 in the control of colonic motility in mice. | Li K et al. | β | 2013 | β |
| Astroglial CB1 cannabinoid receptors regulate leptin signaling in mouse brain astrocytes. | Bosier B et al. | β | 2013 | β |
| Autism-associated neuroligin-3 mutations commonly disrupt tonic endocannabinoid signaling. | FΓΆldy C et al. | β | 2013 | β |
| Cannabidiol as potential anticancer drug. | Massi P et al. | β | 2013 | β |
| Cannabinoid 1 receptors in keratinocytes modulate proinflammatory chemokine secretion and attenuate contact allergic inflammation. | Gaffal E et al. | β | 2013 | β |
| Cannabinoid and opioid interactions: implications for opiate dependence and withdrawal. | Scavone JL et al. | β | 2013 | β |
| Cannabinoid receptors and cholecystokinin in feeding inhibition. | AlΓ©n F et al. | β | 2013 | β |
| Cannabinoid receptors are widely expressed in goldfish: molecular cloning of a CB2-like receptor and evaluation of CB1 and CB2 mRNA expression profiles in different organs. | Cottone E et al. | β | 2013 | β |
| Cannabinoid receptor signaling in progenitor/stem cell proliferation and differentiation. | Galve-Roperh I et al. | β | 2013 | β |
| Computational search for hypotheses concerning the endocannabinoid contribution to the extinction of fear conditioning. | Anastasio TJ | β | 2013 | β |
| Development and characterization of a promising fluorine-18 labelled radiopharmaceutical for in vivo imaging of fatty acid amide hydrolase. | Sadovski O et al. | β | 2013 | β |
| Diacylglycerol lipaseΞ± (DAGLΞ±) and DAGLΞ² cooperatively regulate the production of 2-arachidonoyl glycerol in autaptic hippocampal neurons. | Jain T et al. | β | 2013 | β |
| Diet-dependent modulation of hippocampal expression of endocannabinoid signaling-related proteins in cannabinoid antagonist-treated obese rats. | Rivera P et al. | β | 2013 | β |
| Different expression and function of the endocannabinoid system in human epicardial adipose tissue in relation to heart disease. | Cappellano G et al. | β | 2013 | β |
| Discovery of MK-3168: A PET Tracer for Imaging Brain Fatty Acid Amide Hydrolase. | Liu P et al. | β | 2013 | β |
| Effects of cannabinoids and endocannabinoid hydrolysis inhibition on pentylenetetrazole-induced seizure and electroencephalographic activity in rats. | Vilela LR et al. | β | 2013 | β |
| Effects of cannabis on neurocognitive functioning: recent advances, neurodevelopmental influences, and sex differences. | Crane NA et al. | β | 2013 | β |
| Effects of endocannabinoid and endovanilloid systems on aversive memory extinction. | Laricchiuta D et al. | β | 2013 | β |
| Endocannabinoid signaling in the gut mediates preference for dietary unsaturated fats. | DiPatrizio NV et al. | β | 2013 | β |
| Endocannabinoid system and mood disorders: priming a target for new therapies. | Micale V et al. | β | 2013 | β |
| Endogenous lipid activated G protein-coupled receptors: emerging structural features from crystallography and molecular dynamics simulations. | Hurst DP et al. | β | 2013 | β |
| Exercise-induced endocannabinoid signaling is modulated by intensity. | Raichlen DA et al. | β | 2013 | β |
| Expression of the cannabinoid receptor type 1 in the pituitary of rabbits and its role in the control of LH secretion. | Dall'Aglio C et al. | β | 2013 | β |
| Fatty acid ethanolamides modulate CD36-mRNA through dietary fatty acid manipulation in Syrian Golden hamsters. | Lin L et al. | β | 2013 | β |
| [From cannabis to selective CB2R agonists: molecules with numerous therapeutical virtues]. | Leleu-Chavain N et al. | β | 2013 | β |
| Ghrelin-induced orexigenic effect in rats depends on the metabolic status and is counteracted by peripheral CB1 receptor antagonism. | Alen F et al. | β | 2013 | β |
| Hyperactivity induced by the dopamine D2/D3 receptor agonist quinpirole is attenuated by inhibitors of endocannabinoid degradation in mice. | Luque-Rojas MJ et al. | β | 2013 | β |
| Influence of pre-exposure to morphine on cannabinoid-induced impairment of spatial memory in male rats. | Farahmandfar M et al. | β | 2013 | β |
| Inhibition of FAAH and activation of PPAR: new approaches to the treatment of cognitive dysfunction and drug addiction. | Panlilio LV et al. | β | 2013 | β |
| Involvement of cannabinoid receptors in the amygdala and prefrontal cortex of rats in fear learning, consolidation, retrieval and extinction. | Kuhnert S et al. | β | 2013 | β |
| Lipid-binding properties of human ApoD and Lazarillo-related lipocalins: functional implications for cell differentiation. | Ruiz M et al. | β | 2013 | β |
| Lipidomic mass spectrometry and its application in neuroscience. | Enriquez-Algeciras M et al. | β | 2013 | β |
| Marijuana, endocannabinoids, and epilepsy: potential and challenges for improved therapeutic intervention. | Hofmann ME et al. | β | 2013 | β |
| Mechanisms in the bed nucleus of the stria terminalis involved in control of autonomic and neuroendocrine functions: a review. | Crestani CC et al. | β | 2013 | β |
| Molecular mechanisms of cannabinoid addiction. | Fratta W et al. | β | 2013 | β |
| MΓΌller cells express the cannabinoid CB2 receptor in the vervet monkey retina. | Bouskila J et al. | β | 2013 | β |
| Novelty-induced emotional arousal modulates cannabinoid effects on recognition memory and adrenocortical activity. | Campolongo P et al. | β | 2013 | β |
| Palmitoylethanolamide: from endogenous cannabimimetic substance to innovative medicine for the treatment of cannabis dependence. | Coppola M et al. | β | 2013 | β |
| Prospects for cannabinoid therapies in viral encephalitis. | Solbrig MV et al. | β | 2013 | β |
| Psychobiotics: a novel class of psychotropic. | Dinan TG et al. | β | 2013 | β |
| Quantitative LC-MS/MS analysis of arachidonoyl amino acids in mouse brain with treatment of FAAH inhibitor. | Han B et al. | β | 2013 | β |
| Quantum mechanics/molecular mechanics modeling of fatty acid amide hydrolase reactivation distinguishes substrate from irreversible covalent inhibitors. | Lodola A et al. | β | 2013 | β |
| Radiosynthesis and evaluation of [ΒΉΒΉC-carbonyl]-labeled carbamates as fatty acid amide hydrolase radiotracers for positron emission tomography. | Wilson AA et al. | β | 2013 | β |
| Striatal GABAergic and cortical glutamatergic neurons mediate contrasting effects of cannabinoids on cortical network synchrony. | Sales-Carbonell C et al. | β | 2013 | β |
| Substrate-selective COX-2 inhibition decreases anxiety via endocannabinoid activation. | Hermanson DJ et al. | β | 2013 | β |
| Synaptic targets of Ξ9-tetrahydrocannabinol in the central nervous system. | Hoffman AF et al. | β | 2013 | β |
| Targeted lipidomics in Drosophila melanogaster identifies novel 2-monoacylglycerols and N-acyl amides. | Tortoriello G et al. | β | 2013 | β |
| Targeting the Endocannabinoid System for Neuroprotection: A <sup>19</sup>F-NMR Study of a Selective FAAH Inhibitor Binding with an Anandamide Carrier Protein, HSA. | Zhuang J et al. | β | 2013 | β |
| Temporal and behavioral variability in cannabinoid receptor expression in outbred mice submitted to ethanol-induced locomotor sensitization paradigm. | Coelhoso CC et al. | β | 2013 | β |
| The endocannabinoid system and sex steroid hormone-dependent cancers. | Ayakannu T et al. | β | 2013 | β |
| The endocannabinoid system: a putative role in neurodegenerative diseases. | Di Iorio G et al. | β | 2013 | β |
| The endocannabinoid system as a possible target to treat both the cognitive and emotional features of post-traumatic stress disorder (PTSD). | Trezza V et al. | β | 2013 | β |
| The fatty acid amide hydrolase inhibitor, URB597, promotes retinal ganglion cell neuroprotection in a rat model of optic nerve axotomy. | Slusar JE et al. | β | 2013 | β |
| The neural correlates of mental rotation abilities in cannabis-abusing patients with schizophrenia: an FMRI study. | Potvin S et al. | β | 2013 | β |
| The neuroprotective role of endocannabinoids against chemical-induced injury and other adverse effects. | Zogopoulos P et al. | β | 2013 | β |
| The role of endocannabinoids in pain modulation. | Zogopoulos P et al. | β | 2013 | β |
| The role of fatty acid amide hydrolase inhibition in nicotine reward and dependence. | Muldoon PP et al. | β | 2013 | β |
| Thyroid hormone signaling and homeostasis during aging. | Bowers J et al. | β | 2013 | β |
| Type-1 (CB1) cannabinoid receptor promotes neuronal differentiation and maturation of neural stem cells. | Compagnucci C et al. | β | 2013 | β |
| Using the endocannabinoid system as a neuroprotective strategy in perinatal hypoxic-ischemic brain injury. | Lara-Celador I et al. | β | 2013 | β |
| Ventral tegmental area cannabinoid type-1 receptors control voluntary exercise performance. | Dubreucq S et al. | β | 2013 | β |
| Wagging the Tail: Essential Role of Substrate Flexibility in FAAH Catalysis. | Palermo G et al. | β | 2013 | β |
| 15-Deoxy-ΞΒΉΒ²,ΒΉβ΄-prostaglandin Jβ-glycerol, a putative metabolite of 2-arachidonyl glycerol and a peroxisome proliferator-activated receptor Ξ³ ligand, modulates nuclear factor of activated T cells. | Raman P et al. | β | 2012 | β |
| A2A adenosine receptor antagonism enhances synaptic and motor effects of cocaine via CB1 cannabinoid receptor activation. | Tozzi A et al. | β | 2012 | β |
| A CBβ/CBβ receptor agonist, WIN 55,212-2, exerts its therapeutic effect in a viral autoimmune model of multiple sclerosis by restoring self-tolerance to myelin. | Arevalo-Martin A et al. | β | 2012 | β |
| Activation of type 5 metabotropic glutamate receptors and diacylglycerol lipase-Ξ± initiates 2-arachidonoylglycerol formation and endocannabinoid-mediated analgesia. | Gregg LC et al. | β | 2012 | β |
| Adenosine A(2A)-cannabinoid CB(1) receptor interaction: an integrative mechanism in striatal glutamatergic neurotransmission. | Tebano MT et al. | β | 2012 | β |
| A key agonist-induced conformational change in the cannabinoid receptor CB1 is blocked by the allosteric ligand Org 27569. | Fay JF et al. | β | 2012 | β |
| Altering endocannabinoid neurotransmission at critical developmental ages: impact on rodent emotionality and cognitive performance. | Trezza V et al. | β | 2012 | β |
| An amyloid Ξ²42-dependent deficit in anandamide mobilization is associated with cognitive dysfunction in Alzheimer's disease. | Jung KM et al. | β | 2012 | β |
| Anti-inflammatory lipoxin A4 is an endogenous allosteric enhancer of CB1 cannabinoid receptor. | Pamplona FA et al. | β | 2012 | β |
| Assay and inhibition of diacylglycerol lipase activity. | Johnston M et al. | β | 2012 | β |
| Bimodal control of fear-coping strategies by CBβ cannabinoid receptors. | Metna-Laurent M et al. | β | 2012 | β |
| Biochemical and pharmacological characterization of human Ξ±/Ξ²-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12). | Navia-Paldanius D et al. | β | 2012 | β |
| Blockade of Ξ²-cell K(ATP) channels by the endocannabinoid, 2-arachidonoylglycerol. | Spivak CE et al. | β | 2012 | β |
| Blocking the postpartum mouse dam's CB1 receptors impairs maternal behavior as well as offspring development and their adult social-emotional behavior. | Schechter M et al. | β | 2012 | β |
| Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia. | Leweke FM et al. | β | 2012 | β |
| Cannabinoid CB1 receptor deficiency increases contextual fear memory under highly aversive conditions and long-term potentiation in vivo. | Jacob W et al. | β | 2012 | β |
| Cannabinoid CBβ receptor restrains accentuated activity of hypothalamic corticotropin-releasing factor and brainstem tyrosine hydroxylase neurons in endotoxemia-induced hypophagia in rats. | Rorato R et al. | β | 2012 | β |
| Cannabinoid receptor 1 in the vagus nerve is dispensable for body weight homeostasis but required for normal gastrointestinal motility. | Vianna CR et al. | β | 2012 | β |
| Cannabinoid receptor-mediated regulation of neuronal activity and signaling in glomeruli of the main olfactory bulb. | Wang ZJ et al. | β | 2012 | β |
| Cannabinoid receptors CB1 and CB2 form functional heteromers in brain. | CallΓ©n L et al. | β | 2012 | β |
| Cannabinoid receptor signaling and modulation of monoamines: implications for psychiatric and neurological disorders. | Van Bockstaele EJ | β | 2012 | β |
| Cannabinoid receptors mediate methamphetamine induction of high frequency gamma oscillations in the nucleus accumbens. | Morra JT et al. | β | 2012 | β |
| Cannabinoids and monoamine neurotransmission with focus on monoamine oxidase. | FiΕ‘ar Z | β | 2012 | β |
| Cannabis and progression to other substance use in young adults: findings from a 13-year prospective population-based study. | Swift W et al. | β | 2012 | β |
| CB1 receptor autoradiographic characterization of the individual differences in approach and avoidance motivation. | Laricchiuta D et al. | β | 2012 | β |
| Central and peripheral cannabinoid receptors as therapeutic targets in the control of food intake and body weight. | Engeli S | β | 2012 | β |
| CNR1 genotype influences HDL-cholesterol response to change in dietary fat intake. | Silver HJ et al. | β | 2012 | β |
| Developmental regulation of CB1-mediated spike-time dependent depression at immature mossy fiber-CA3 synapses. | Caiati MD et al. | β | 2012 | β |
| Differences in spontaneously avoiding or approaching mice reflect differences in CB1-mediated signaling of dorsal striatal transmission. | Laricchiuta D et al. | β | 2012 | β |
| Differential distribution of diacylglycerol lipase-alpha and N-acylphosphatidylethanolamine-specific phospholipase d immunoreactivity in the superficial spinal dorsal horn of rats. | Hegyi Z et al. | β | 2012 | β |
| Distribution of type 1 cannabinoid receptor-expressing neurons in the septal-hypothalamic region of the mouse: colocalization with GABAergic and glutamatergic markers. | Hrabovszky E et al. | β | 2012 | β |
| Effects of chronic oral rimonabant administration on energy budgets of diet-induced obese C57BL/6 mice. | Zhang LN et al. | β | 2012 | β |
| Effects of the anandamide uptake blocker AM404 on food intake depend on feeding status and route of administration. | Reyes-Cabello C et al. | β | 2012 | β |
| Effects of Ξ9-tetrahydrocannabinol administration on human encoding and recall memory function: a pharmacological FMRI study. | Bossong MG et al. | β | 2012 | β |
| Effects of Ξ΄9-tetrahydrocannabinol on human working memory function. | Bossong MG et al. | β | 2012 | β |
| Electroacupuncture inhibits CB1 upregulation induced by ethanol withdrawal in mice. | Escosteguy-Neto JC et al. | β | 2012 | β |
| Endocannabinoid CB1 receptors modulate visual output from the thalamus. | Dasilva MA et al. | β | 2012 | β |
| Endocannabinoids and retrograde modulation of synaptic transmission. | Ohno-Shosaku T et al. | β | 2012 | β |
| Endocannabinoids at the synapse a decade after the dies mirabilis (29 March 2001): what we still do not know. | Alger BE | β | 2012 | β |
| Endocannabinoid signaling and synaptic function. | Castillo PE et al. | β | 2012 | β |
| Endocannabinoid signaling in the amygdala: anatomy, synaptic signaling, behavior, and adaptations to stress. | Ramikie TS et al. | β | 2012 | β |
| Endocannabinoids in amygdala and nucleus accumbens mediate social play reward in adolescent rats. | Trezza V et al. | β | 2012 | β |
| Epigenetic regulation of fatty acid amide hydrolase in Alzheimer disease. | D'Addario C et al. | β | 2012 | β |
| Expression and localization of the cannabinoid receptor type 1 and the enzyme fatty acid amide hydrolase in the retina of vervet monkeys. | Bouskila J et al. | β | 2012 | β |
| Expression pattern of the cannabinoid receptor genes in the frontal cortex ofΒ mood disorder patients and mice selectively bred for high and low fear. | Choi K et al. | β | 2012 | β |
| Extrasynaptic neurotransmission in the modulation of brain function. Focus on the striatal neuronal-glial networks. | Fuxe K et al. | β | 2012 | β |
| Fear relief-toward a new conceptual frame work and what endocannabinoids gotta do with it. | Riebe CJ et al. | β | 2012 | β |
| Fine-tuning of defensive behaviors in the dorsal periaqueductal gray by atypical neurotransmitters. | FogaΓ§a MV et al. | β | 2012 | β |
| Gating the polarity of endocannabinoid-mediated synaptic plasticity by nitric oxide in the spinal locomotor network. | Song J et al. | β | 2012 | β |
| Genetic dissection of the role of cannabinoid type-1 receptors in the emotional consequences of repeated social stress in mice. | Dubreucq S et al. | β | 2012 | β |
| Identification and characterization of carprofen as a multitarget fatty acid amide hydrolase/cyclooxygenase inhibitor. | Favia AD et al. | β | 2012 | β |
| Inhibiting the breakdown of endogenous opioids and cannabinoids to alleviate pain. | Roques BP et al. | β | 2012 | β |
| Inhibition of monoacylglycerol lipase attenuates vomiting in Suncus murinus and 2-arachidonoyl glycerol attenuates nausea in rats. | Sticht MA et al. | β | 2012 | β |
| Intrinsic up-regulation of 2-AG favors an area specific neuronal survival in different in vitro models of neuronal damage. | Kallendrusch S et al. | β | 2012 | β |
| Latest advances in novel cannabinoid CB(2) ligands for drug abuse and their therapeutic potential. | Yang P et al. | β | 2012 | β |
| Medial prefrontal cortex endocannabinoid system modulates baroreflex activity through CB(1) receptors. | Ferreira-Junior NC et al. | β | 2012 | β |
| Metamizol, a non-opioid analgesic, acts via endocannabinoids in the PAG-RVM axis during inflammation in rats. | Escobar W et al. | β | 2012 | β |
| Mitochondrial CBβ receptors regulate neuronal energy metabolism. | BΓ©nard G et al. | β | 2012 | β |
| Molecular and cellular pathways as a target of therapeutic hypothermia: pharmacological aspect. | Han HS et al. | β | 2012 | β |
| Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders. | Campos AC et al. | β | 2012 | β |
| Neuron to astrocyte communication via cannabinoid receptors is necessary for sustained epileptiform activity in rat hippocampus. | Coiret G et al. | β | 2012 | β |
| New insights on endocannabinoid transmission in psychomotor disorders. | Giuffrida A et al. | β | 2012 | β |
| Opposing roles for cannabinoid receptor type-1 (CBβ) and transient receptor potential vanilloid type-1 channel (TRPV1) on the modulation of panic-like responses in rats. | Casarotto PC et al. | β | 2012 | β |
| Paraventricular nucleus anandamide signaling alters eating and substrate oxidation. | Chapman CD et al. | β | 2012 | β |
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| Peripheral FAAH inhibition causes profound antinociception and protects against indomethacin-induced gastric lesions. | Sasso O et al. | β | 2012 | β |
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| Pretreatment with the monoacylglycerol lipase inhibitor URB602 protects from the long-term consequences of neonatal hypoxic-ischemic brain injury in rats. | Carloni S et al. | β | 2012 | β |
| Prolonged oral cannabinoid administration prevents neuroinflammation, lowers Ξ²-amyloid levels and improves cognitive performance in Tg APP 2576 mice. | MartΓn-Moreno AM et al. | β | 2012 | β |
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| Regional changes in type 1 cannabinoid receptor availability in Parkinson's disease in vivo. | Van Laere K et al. | β | 2012 | β |
| RGS4 is required for dopaminergic control of striatal LTD and susceptibility to parkinsonian motor deficits. | Lerner TN et al. | β | 2012 | β |
| Site-specific and time-dependent activation of the endocannabinoid system after transection of long-range projections. | Kallendrusch S et al. | β | 2012 | β |
| The amnesic effect of intra-central amygdala administration of a cannabinoid CB1 receptor agonist, WIN55,212-2, is mediated by a Ξ²-1 noradrenergic system in rat. | Zarrindast MR et al. | β | 2012 | β |
| The anandamide transport inhibitor AM404 reduces the rewarding effects of nicotine and nicotine-induced dopamine elevations in the nucleus accumbens shell in rats. | Scherma M et al. | β | 2012 | β |
| The cannabinoid agonist WIN55212-2 decreases L-DOPA-induced PKA activation and dyskinetic behavior in 6-OHDA-treated rats. | Martinez A et al. | β | 2012 | β |
| The endocannabinoid system in anxiety, fear memory and habituation. | Ruehle S et al. | β | 2012 | β |
| The endocannabinoid transport inhibitor AM404 differentially modulates recognition memory in rats depending on environmental aversiveness. | Campolongo P et al. | β | 2012 | β |
| The faah gene is the first direct target of estrogen in the testis: role of histone demethylase LSD1. | Grimaldi P et al. | β | 2012 | β |
| The genetic basis of the endocannabinoid system and drug addiction in humans. | LΓ³pez-Moreno JA et al. | β | 2012 | β |
| The role of the endocannabinoid system in skeletal muscle and metabolic adaptations to exercise: potential implications for the treatment of obesity. | Heyman E et al. | β | 2012 | β |
| The serine hydrolases MAGL, ABHD6 and ABHD12 as guardians of 2-arachidonoylglycerol signalling through cannabinoid receptors. | Savinainen JR et al. | β | 2012 | β |
| The thrifty lipids: endocannabinoids and the neural control of energy conservation. | DiPatrizio NV et al. | β | 2012 | β |
| Time-dependent effects of treadmill exercise on aversive memory and cyclooxygenase pathway function. | Lovatel GA et al. | β | 2012 | β |
| Toward a mechanistic understanding of how variability in neurobiology shapes individual differences in behavior. | Bogdan R et al. | β | 2012 | β |
| Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome. | Jung KM et al. | β | 2012 | β |
| Wired to run: exercise-induced endocannabinoid signaling in humans and cursorial mammals with implications for the 'runner's high'. | Raichlen DA et al. | β | 2012 | β |
| Ξ²-Lactones Inhibit N-acylethanolamine Acid Amidase by S-Acylation of the Catalytic N-Terminal Cysteine. | Armirotti A et al. | β | 2012 | β |
| 15-Deoxy-delta12,14-prostaglandin J2-glycerol ester, a putative metabolite of 2-arachidonyl glycerol, activates peroxisome proliferator activated receptor gamma. | Raman P et al. | β | 2011 | β |
| 385 C/A polymorphism of the fatty acid amide hydrolase gene is associated with metabolic syndrome in the Chinese Han population. | Zeng J et al. | β | 2011 | β |
| Activation of cannabinoid CB1 receptors in the central amygdala impairs inhibitory avoidance memory consolidation via NMDA receptors. | Ghiasvand M et al. | β | 2011 | β |
| Activity-based protein profiling of organophosphorus and thiocarbamate pesticides reveals multiple serine hydrolase targets in mouse brain. | Nomura DK et al. | β | 2011 | β |
| Acute overactive endocannabinoid signaling induces glucose intolerance, hepatic steatosis, and novel cannabinoid receptor 1 responsive genes. | Ruby MA et al. | β | 2011 | β |
| Adipose tissue endocannabinoid system gene expression: depot differences and effects of diet and exercise. | You T et al. | β | 2011 | β |
| Allosteric modulation of glycine receptors. | Yevenes GE et al. | β | 2011 | β |
| Anandamide enhances expression of heat shock proteins Hsp70 and Hsp25 in rat lungs. | KopczyΕska B et al. | β | 2011 | β |
| Anxiolytic-like effect induced by the cannabinoid CB1 receptor agonist, arachydonilcyclopropylamide (ACPA), in the rat amygdala is mediated through the D1 and D2 dopaminergic systems. | Zarrindast MR et al. | β | 2011 | β |
| Application of a SCC-DFTB QM/MM approach to the investigation of the catalytic mechanism of fatty acid amide hydrolase. | Capoferri L et al. | β | 2011 | β |
| Assortment of GABAergic plasticity in the cortical interneuron melting pot. | MΓ©ndez P et al. | β | 2011 | β |
| Binding properties of antagonists to cannabinoid receptors in intact cells. | Wennerberg M et al. | β | 2011 | β |
| Cannabidiol and other cannabinoids reduce microglial activation in vitro and in vivo: relevance to Alzheimer's disease. | MartΓn-Moreno AM et al. | β | 2011 | β |
| Cannabinoid as a neuroprotective strategy in perinatal hypoxic-ischemic injury. | Alonso-Alconada D et al. | β | 2011 | β |
| Cannabinoid CB1 receptors regulate neuronal TNF-Ξ± effects in experimental autoimmune encephalomyelitis. | Rossi S et al. | β | 2011 | β |
| Cannabinoid receptor type 1 protects nigrostriatal dopaminergic neurons against MPTP neurotoxicity by inhibiting microglial activation. | Chung YC et al. | β | 2011 | β |
| Cannabinoids, endocannabinoids, and cancer. | Hermanson DJ et al. | β | 2011 | β |
| Cannabis sativa and the endogenous cannabinoid system: therapeutic potential for appetite regulation. | Farrimond JA et al. | β | 2011 | β |
| Cannabis use in young people: the risk for schizophrenia. | Casadio P et al. | β | 2011 | β |
| CB1 receptors and post-ischemic brain damage: studies on the toxic and neuroprotective effects of cannabinoids in rat organotypic hippocampal slices. | Landucci E et al. | β | 2011 | β |
| Cell-type-specific CCK2 receptor signaling underlies the cholecystokinin-mediated selective excitation of hippocampal parvalbumin-positive fast-spiking basket cells. | Lee SY et al. | β | 2011 | β |
| Central endocannabinoid signaling regulates hepatic glucose production and systemic lipolysis. | O'Hare JD et al. | β | 2011 | β |
| Clozapine and SCH 23390 prevent the spatial working memory disruption induced by Ξ9-THC administration into the medial prefrontal cortex. | Rodrigues LC et al. | β | 2011 | β |
| Comparison of Cannabinoid CB(1) Receptor Binding in Adolescent and Adult Rats: A Positron Emission Tomography Study Using [F]MK-9470. | Verdurand M et al. | β | 2011 | β |
| Complementary synaptic distribution of enzymes responsible for synthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in the human hippocampus. | LudΓ‘nyi A et al. | β | 2011 | β |
| Control of striatal signaling by g protein regulators. | Xie K et al. | β | 2011 | β |
| Covalent inhibitors of fatty acid amide hydrolase: a rationale for the activity of piperidine and piperazine aryl ureas. | Palermo G et al. | β | 2011 | β |
| Depolarizing and calcium-mobilizing stimuli fail to enhance synthesis and release of endocannabinoids from rat brain cerebral cortex slices. | Sarmad S et al. | β | 2011 | β |
| Developmental consequences of perinatal cannabis exposure: behavioral and neuroendocrine effects in adult rodents. | Campolongo P et al. | β | 2011 | β |
| Diacylglycerol lipase-alpha and -beta control neurite outgrowth in neuro-2a cells through distinct molecular mechanisms. | Jung KM et al. | β | 2011 | β |
| Direct intra-accumbal infusion of a beta-adrenergic receptor antagonist abolishes WIN 55,212-2-induced aversion. | Carvalho AF et al. | β | 2011 | β |
| Disruption of frontal ΞΈ coherence by Ξ9-tetrahydrocannabinol is associated with positive psychotic symptoms. | Morrison PD et al. | β | 2011 | β |
| Distribution of diacylglycerol lipase alpha, an endocannabinoid synthesizing enzyme, in the rat forebrain. | SuΓ‘rez J et al. | β | 2011 | β |
| Dysregulated mTORC1-Dependent Translational Control: From Brain Disorders to Psychoactive Drugs. | Santini E et al. | β | 2011 | β |
| Early exposure to environmental enrichment alters the expression of genes of the endocannabinoid system. | El Rawas R et al. | β | 2011 | β |
| Endocannabinoid 2-arachidonoylglycerol protects neurons against Ξ²-amyloid insults. | Chen X et al. | β | 2011 | β |
| Endocannabinoid influence in drug reinforcement, dependence and addiction-related behaviors. | Serrano A et al. | β | 2011 | β |
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| Endocannabinoids and motor behavior: CB1 receptors also control running activity. | Chaouloff F et al. | β | 2011 | β |
| Endocannabinoids and stress. | Riebe CJ et al. | β | 2011 | β |
| Endocannabinoids and traumatic brain injury. | Shohami E et al. | β | 2011 | β |
| Endocannabinoid signal in the gut controls dietary fat intake. | DiPatrizio NV et al. | β | 2011 | β |
| Endocannabinoid tone versus constitutive activity of cannabinoid receptors. | Howlett AC et al. | β | 2011 | β |
| Evaluation of the emotional phenotype and serotonergic neurotransmission of fatty acid amide hydrolase-deficient mice. | Cassano T et al. | β | 2011 | β |
| Evidence for involvement of the insula in the psychotropic effects of THC in humans: a double-blind, randomized pharmacological MRI study. | van Hell HH et al. | β | 2011 | β |
| Expression of the cannabinoid system in muscle: effects of a high-fat diet and CB1 receptor blockade. | Crespillo A et al. | β | 2011 | β |
| Facilitation of CB1 receptor-mediated neurotransmission decreases marble burying behavior in mice. | Gomes FV et al. | β | 2011 | β |
| Functional characterization of putative cholesterol binding sequence (CRAC) in human type-1 cannabinoid receptor. | Oddi S et al. | β | 2011 | β |
| GABAergic and cortical and subcortical glutamatergic axon terminals contain CB1 cannabinoid receptors in the ventromedial nucleus of the hypothalamus. | Reguero L et al. | β | 2011 | β |
| Inhibition of COX-2 expression by endocannabinoid 2-arachidonoylglycerol is mediated via PPAR-Ξ³. | Du H et al. | β | 2011 | β |
| Inhibition of fatty acid amide hydrolase unmasks CB1 receptor and TRPV1 channel-mediated modulation of glutamatergic synaptic transmission in midbrain periaqueductal grey. | Kawahara H et al. | β | 2011 | β |
| In search of the neurobiological substrates for social playfulness in mammalian brains. | Siviy SM et al. | β | 2011 | β |
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| Is lipid signaling through cannabinoid 2 receptors part of a protective system? | Pacher P et al. | β | 2011 | β |
| Lasting impacts of prenatal cannabis exposure and the role of endogenous cannabinoids in the developing brain. | Wu CS et al. | β | 2011 | β |
| Local pretreatment with the cannabinoid CB1 receptor antagonist AM251 attenuates methamphetamine intra-accumbens self-administration. | Rodriguez JS et al. | β | 2011 | β |
| Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease. | BlΓ‘zquez C et al. | β | 2011 | β |
| Mass spectrometry as test bench for medicinal chemistry studies. | Seraglia R et al. | β | 2011 | β |
| Mechanisms underlying input-specific expression of endocannabinoid-mediated synaptic plasticity in the dorsal cochlear nucleus. | Zhao Y et al. | β | 2011 | β |
| Mechanisms underlying the onset and expression of levodopa-induced dyskinesia and their pharmacological manipulation. | Iravani MM et al. | β | 2011 | β |
| Methods of the pharmacological imaging of the cannabinoid system (PhICS) study: towards understanding the role of the brain endocannabinoid system in human cognition. | van Hell HH et al. | β | 2011 | β |
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| Molecular sites for the positive allosteric modulation of glycine receptors by endocannabinoids. | YΓ©venes GE et al. | β | 2011 | β |
| Moving bliss: a new anandamide transporter. | Marsicano G et al. | β | 2011 | β |
| N-arachidonoyl-L-serine is neuroprotective after traumatic brain injury by reducing apoptosis. | Cohen-Yeshurun A et al. | β | 2011 | β |
| Obesity-dependent cannabinoid modulation of proliferation in adult neurogenic regions. | Rivera P et al. | β | 2011 | β |
| Peripheral analgesia: Hitting pain where it hurts. | McDougall JJ | β | 2011 | β |
| Pharmacological activation of kainate receptors drives endocannabinoid mobilization. | LourenΓ§o J et al. | β | 2011 | β |
| Polymodal activation of the endocannabinoid system in the extended amygdala. | Puente N et al. | β | 2011 | β |
| Propofol enhances memory formation via an interaction with the endocannabinoid system. | Hauer D et al. | β | 2011 | β |
| Putative role of endocannabinoid signaling in the etiology of depression and actions of antidepressants. | Gorzalka BB et al. | β | 2011 | β |
| Reduction of body weight, liver steatosis and expression of stearoyl-CoA desaturase 1 by the isoflavone daidzein in diet-induced obesity. | Crespillo A et al. | β | 2011 | β |
| Requirement for the endocannabinoid system in social interaction impairment induced by coactivation of dopamine D1 and D2 receptors in the piriform cortex. | Zenko M et al. | β | 2011 | β |
| Role of brainstem GABAergic signaling in central cannabinoid receptor evoked sympathoexcitation and pressor responses in conscious rats. | Ibrahim BM et al. | β | 2011 | β |
| (R)-Profens are substrate-selective inhibitors of endocannabinoid oxygenation by COX-2. | Duggan KC et al. | β | 2011 | β |
| Small molecule analysis and imaging of fatty acids in the zebra finch song system using time-of-flight-secondary ion mass spectrometry. | Amaya KR et al. | β | 2011 | β |
| Social encounter with a novel partner in adolescent rats: activation of the central endocannabinoid system. | Marco EM et al. | β | 2011 | β |
| Soluble epoxide hydrolase inhibition, epoxygenated fatty acids and nociception. | Wagner K et al. | β | 2011 | β |
| Supply and demand for endocannabinoids. | Alger BE et al. | β | 2011 | β |
| The cannabinoid WIN 55,212-2-mediated protection of dentate gyrus granule cells is driven by CB1 receptors and modulated by TRPA1 and Cav 2.2 channels. | Koch M et al. | β | 2011 | β |
| The Central Role of Glia in Pathological Pain and the Potential of Targeting the Cannabinoid 2 Receptor for Pain Relief. | Wilkerson JL et al. | β | 2011 | β |
| The distinct role of medium spiny neurons and cholinergic interneurons in the Dβ/AβA receptor interaction in the striatum: implications for Parkinson's disease. | Tozzi A et al. | β | 2011 | β |
| The Dopamine and Cannabinoid Interaction in the Modulation of Emotions and Cognition: Assessing the Role of Cannabinoid CB1 Receptor in Neurons Expressing Dopamine D1 Receptors. | Terzian AL et al. | β | 2011 | β |
| The endocannabinoid 2-arachidonoylglycerol mediates D1 and D2 receptor cooperative enhancement of rat nucleus accumbens core neuron firing. | Seif T et al. | β | 2011 | β |
| The Endocannabinoid System as Pharmacological Target Derived from Its CNS Role in Energy Homeostasis and Reward. Applications in Eating Disorders and Addiction. | Viveros MP et al. | β | 2011 | β |
| The hypophysial pars tuberalis transduces photoperiodic signals via multiple pathways and messenger molecules. | Yasuo S et al. | β | 2011 | β |
| The selective anandamide transport inhibitor VDM11 attenuates reinstatement of nicotine seeking behaviour, but does not affect nicotine intake. | Gamaleddin I et al. | β | 2011 | β |
| Unraveling the complexities of cannabinoid receptor 2 (CB2) immune regulation in health and disease. | Basu S et al. | β | 2011 | β |
| Update on the endocannabinoid system as an anticancer target. | Malfitano AM et al. | β | 2011 | β |
| Xenoestrogens elicit a modulation of endocannabinoid system and estrogen receptors in 4NP treated goldfish, Carassius auratus. | Pomatto V et al. | β | 2011 | β |
| Abnormal sensitivity of cannabinoid CB1 receptors in the striatum of mice with experimental amyotrophic lateral sclerosis. | Rossi S et al. | β | 2010 | β |
| Activation of TRPC6 channels promotes endocannabinoid biosynthesis in neuronal CAD cells. | Bardell TK et al. | β | 2010 | β |
| Adenosine-cannabinoid receptor interactions. Implications for striatal function. | FerrΓ© S et al. | β | 2010 | β |
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| A lipid pathway for ligand binding is necessary for a cannabinoid G protein-coupled receptor. | Hurst DP et al. | β | 2010 | β |
| Analgesia: Pain control at the periphery. | Kingwell K | β | 2010 | β |
| Anandamide potentiation of miniature spontaneous excitatory synaptic transmission is mediated via IP3 pathway. | Sang N et al. | β | 2010 | β |
| An endocannabinoid system is localized to the hypophysial pars tuberalis of Syrian hamsters and responds to photoperiodic changes. | Yasuo S et al. | β | 2010 | β |
| Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT1A receptors. | Zanelati TV et al. | β | 2010 | β |
| A peripherally restricted cannabinoid receptor agonist produces robust anti-nociceptive effects in rodent models of inflammatory and neuropathic pain. | Yu XH et al. | β | 2010 | β |
| A synaptocentric view of the neuroendocrine response to stress. | Wamsteeker JI et al. | β | 2010 | β |
| Bimodal control of stimulated food intake by the endocannabinoid system. | Bellocchio L et al. | β | 2010 | β |
| Biodistribution and dosimetry in humans of two inverse agonists to image cannabinoid CB1 receptors using positron emission tomography. | Terry GE et al. | β | 2010 | β |
| Cannabidiol inhibitory effect on marble-burying behaviour: involvement of CB1 receptors. | Casarotto PC et al. | β | 2010 | β |
| Cannabinoid CB1 receptor-interacting proteins: novel targets for central nervous system drug discovery? | Smith TH et al. | β | 2010 | β |
| Cannabinoid modulation of limbic forebrain noradrenergic circuitry. | Carvalho AF et al. | β | 2010 | β |
| Cannabinoids and anxiety. | Moreira FA et al. | β | 2010 | β |
| Cannabinoids and the gut: new developments and emerging concepts. | Izzo AA et al. | β | 2010 | β |
| Cannabinoids and their interactions with diazepam on modulation of serum corticosterone concentration in male mice. | Saber-Tehrani A et al. | β | 2010 | β |
| Cannabinoids modulate cell survival in embryoid bodies. | Nones J et al. | β | 2010 | β |
| CB1 receptor deficiency decreases wheel-running activity: consequences on emotional behaviours and hippocampal neurogenesis. | Dubreucq S et al. | β | 2010 | β |
| Contribution of limbic norepinephrine to cannabinoid-induced aversion. | Carvalho AF et al. | β | 2010 | β |
| Dendritic Cell Regulation by Cannabinoid-Based Drugs. | Svensson M et al. | β | 2010 | β |
| Direct and indirect effects of cannabinoids on in vitro GABA release in the rat arcuate nucleus. | Menzies JR et al. | β | 2010 | β |
| Distinct coincidence detectors govern the corticostriatal spike timing-dependent plasticity. | Fino E et al. | β | 2010 | β |
| Dynamic changes of anandamide in the cerebrospinal fluid of Parkinson's disease patients. | Pisani V et al. | β | 2010 | β |
| Effects of caffeine on striatal neurotransmission: focus on cannabinoid CB1 receptors. | Rossi S et al. | β | 2010 | β |
| Effects of SR141716A on Cognitive and Depression-Related Behavior in an Animal Model of Premotor Parkinson's Disease. | Tadaiesky MT et al. | β | 2010 | β |
| Effects of the endogenous PPAR-alpha agonist, oleoylethanolamide on MDMA-induced cognitive deficits in mice. | Plaza-Zabala A et al. | β | 2010 | β |
| Endocannabinoid binding to the cannabinoid receptors: what is known and what remains unknown. | Reggio PH | β | 2010 | β |
| Endocannabinoid-mediated synaptically evoked suppression of GABAergic transmission in the cerebellar cortex. | Urbanski MJ et al. | β | 2010 | β |
| Endocannabinoids contribute to metabotropic glutamate receptor-mediated inhibition of GABA release onto hippocampal CA3 pyramidal neurons in an isolated neuron/bouton preparation. | Inada H et al. | β | 2010 | β |
| Endocannabinoids potentiate synaptic transmission through stimulation of astrocytes. | Navarrete M et al. | β | 2010 | β |
| Enhanced cognitive performance of dopamine D3 receptor "knock-out" mice in the step-through passive-avoidance test: assessing the role of the endocannabinoid/endovanilloid systems. | Micale V et al. | β | 2010 | β |
| Enhanced endocannabinoid signaling elevates neuronal excitability in fragile X syndrome. | Zhang L et al. | β | 2010 | β |
| Glucocorticoids, stress and obesity. | Pasquali R et al. | β | 2010 | β |
| G-protein coupled receptors in stem cell self-renewal and differentiation. | Kobayashi NR et al. | β | 2010 | β |
| Inactivation of lipid glyceryl ester metabolism in human THP1 monocytes/macrophages by activated organophosphorus insecticides: role of carboxylesterases 1 and 2. | Xie S et al. | β | 2010 | β |
| Inhibition of fatty-acid amide hydrolase and CB1 receptor antagonism differentially affect behavioural responses in normal and PCP-treated rats. | Seillier A et al. | β | 2010 | β |
| Inhibitors of monoacylglycerol lipase, fatty-acid amide hydrolase and endocannabinoid transport differentially suppress capsaicin-induced behavioral sensitization through peripheral endocannabinoid mechanisms. | Spradley JM et al. | β | 2010 | β |
| Interaction between cytokines, cannabinoids and the nervous system. | Jean-Gilles L et al. | β | 2010 | β |
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| Involvement of the prelimbic prefrontal cortex on cannabidiol-induced attenuation of contextual conditioned fear in rats. | Lemos JI et al. | β | 2010 | β |
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| Localization and function of the cannabinoid CB1 receptor in the anterolateral bed nucleus of the stria terminalis. | Puente N et al. | β | 2010 | β |
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| N-acylethanolamine levels and expression of their metabolizing enzymes during pregnancy. | Fonseca BM et al. | β | 2010 | β |
| Neural encoding of psychomotor activation in the nucleus accumbens core, but not the shell, requires cannabinoid receptor signaling. | Morra JT et al. | β | 2010 | β |
| Neuroprotective effect of WIN 55,212-2 pretreatment against focal cerebral ischemia through activation of extracellular signal-regulated kinases in rats. | Hu B et al. | β | 2010 | β |
| NSAIDs, Opioids, Cannabinoids and the Control of Pain by the Central Nervous System. | Vanegas H et al. | β | 2010 | β |
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| Preservation of striatal cannabinoid CB1 receptor function correlates with the antianxiety effects of fatty acid amide hydrolase inhibition. | Rossi S et al. | β | 2010 | β |
| Rapid alteration of stress-induced hypothalamic-pituitary-adrenal hormone secretion in the rat: a comparison of glucocorticoids and cannabinoids. | Ginsberg AB et al. | β | 2010 | β |
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| Regulation of plasticity of glutamate synapses by endocannabinoids and the cyclic-AMP/protein kinase A pathway in midbrain dopamine neurons. | Haj-Dahmane S et al. | β | 2010 | β |
| Retrograde endocannabinoid signaling reduces GABAergic synaptic transmission to gonadotropin-releasing hormone neurons. | Farkas I et al. | β | 2010 | β |
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| Strategies for discovering and derisking covalent, irreversible enzyme inhibitors. | Johnson DS et al. | β | 2010 | β |
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| Ten years of Nature Reviews Neuroscience: insights from the highly cited. | Luo L et al. | β | 2010 | β |
| The CB1 inverse agonist AM251, but not the CB1 antagonist AM4113, enhances retention of contextual fear conditioning in rats. | Sink KS et al. | β | 2010 | β |
| The constitutive production of the endocannabinoid 2-arachidonoylglycerol participates in oligodendrocyte differentiation. | Gomez O et al. | β | 2010 | β |
| The discovery of central monoamine neurons gave volume transmission to the wired brain. | Fuxe K et al. | β | 2010 | β |
| The endocannabinoid 2-arachidonoylglycerol (2-AG) and metabolizing enzymes during rat fetoplacental development: a role in uterine remodelling. | Fonseca BM et al. | β | 2010 | β |
| The endocannabinoid system and psychiatric disorders. | Parolaro D et al. | β | 2010 | β |
| The endocannabinoid system: a new entry in remote cell death mechanisms. | Viscomi MT et al. | β | 2010 | β |
| The expression level of CB1 and CB2 receptors determines their efficacy at inducing apoptosis in astrocytomas. | Cudaback E et al. | β | 2010 | β |
| The role of endocannabinoid signaling in motor control. | El Manira A et al. | β | 2010 | β |
| The tempted brain eats: pleasure and desire circuits in obesity and eating disorders. | Berridge KC et al. | β | 2010 | β |
| Transient receptor potential vanilloid 1 channels control acetylcholine/2-arachidonoylglicerol coupling in the striatum. | Musella A et al. | β | 2010 | β |
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| Validation and application of an LC-MS/MS method for quantitation of three fatty acid ethanolamides as biomarkers for fatty acid hydrolase inhibition in human plasma. | Jian W et al. | β | 2010 | β |
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