Metabolism and disposition kinetics of nicotine.
paper
Cited
Public
Unavailable
- Authors
- Hukkanen, Janne; Jacob, Peyton; Benowitz, Neal L
- Year
- 2005
- Journal
- Pharmacological reviews
- PMID
- 15734728
- DOI
- 10.1124/pr.57.1.3
Nicotine is of importance as the addictive chemical in tobacco, pharmacotherapy for smoking cessation, a potential medication for several diseases, and a useful probe drug for phenotyping cytochrome P450 2A6 (CYP2A6). We review current knowledge about the metabolism and disposition kinetics of nicotine, some other naturally occurring tobacco alkaloids, and nicotine analogs that are under development as potential therapeutic agents. The focus is on studies in humans, but animal data are mentioned when relevant to the interpretation of human data. The pathways of nicotine metabolism are described in detail. Absorption, distribution, metabolism, and excretion of nicotine and related compounds are reviewed. Enzymes involved in nicotine metabolism including cytochrome P450 enzymes, aldehyde oxidase, flavin-containing monooxygenase 3, amine N-methyltransferase, and UDP-glucuronosyltransferases are represented, as well as factors affecting metabolism, such as genetic variations in metabolic enzymes, effects of diet, age, gender, pregnancy, liver and kidney diseases, and racial and ethnic differences. Also effects of smoking and various inhibitors and inducers, including oral contraceptives, on nicotine metabolism are discussed. Due to the significance of the CYP2A6 enzyme in nicotine clearance, special emphasis is given to the effects and population distributions of CYP2A6 alleles and the regulation of CYP2A6 enzyme.
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| Maternal nicotine metabolism moderates the impact of maternal cigarette smoking on infant birth weight: A Collaborative Perinatal Project investigation. | Stroud LR et al. | — | 2022 | → |
| Mechanistic Insights into Pyridine Ring Degradation Catalyzed by 2,5-Dihydroxypyridine Dioxygenase NicX. | Wei J et al. | — | 2022 | → |
| Monitoring of changes in illicit drugs, alcohol, and nicotine consumption during Ramadan via wastewater analysis. | Guzel EY | — | 2022 | → |
| Neonatal nicotine exposure changes insulin status in fat depots: sex-related differences. | Rodrigues VDST et al. | — | 2022 | → |
| Nicotine and cotinine quantification after a 4-week inhalation of electronic cigarette vapors in male and female mice using UPLC-MS/MS. | Alasmari F et al. | — | 2022 | → |
| Nicotine Delivery and Pharmacokinetics of an Electronic Cigarette Compared With Conventional Cigarettes in Chinese Adult Smokers: A Randomized Open-Label Crossover Clinical Study. | Guo Y et al. | — | 2022 | → |
| Nicotine Exposure in the U.S. Population: Total Urinary Nicotine Biomarkers in NHANES 2015-2016. | Mazumder S et al. | — | 2022 | → |
| Optimal use of smoking cessation pharmacotherapy. | Mendelsohn C | — | 2022 | → |
| Optimum Urine Cotinine and NNAL Levels to Distinguish Smokers from Non-Smokers by the Changes in Tobacco Control Policy in Korea from 2008 to 2018. | Park EY et al. | — | 2022 | → |
| Perfluoroalkyl Substances and Abdominal Aortic Calcification. | Koskela A et al. | — | 2022 | → |
| Persistent organic pollutants in pregnant women potentially affect child development and thyroid hormone status. | Krönke AA et al. | — | 2022 | → |
| Pharmacological and physiological response in Apoe<sup>-/-</sup> mice exposed to cigarette smoke or e-cigarette aerosols. | Eden MJ et al. | — | 2022 | → |
| Predicting nicotine metabolism across ancestries using genotypes. | Baurley JW et al. | — | 2022 | → |
| Relapse to cotinine seeking in rats: differential effects of sex. | Tan X et al. | — | 2022 | → |
| Secondhand smoke exposure is associated with abnormal P-wave axis. | Skipina TM et al. | — | 2022 | → |
| Secondhand smoke is positively associated with pre-frailty and frailty in non-smoking older adults. | Fu Z et al. | — | 2022 | → |
| Serum Concentrations of Cotinine and Trans-3'-Hydroxycotinine in US Adults: Results From Wave 1 (2013-2014) of the Population Assessment of Tobacco and Health Study. | Sosnoff CS et al. | — | 2022 | → |
| Simultaneous quantification of urinary tobacco and marijuana metabolites using solid-supported liquid-liquid extraction coupled with liquid chromatography tandem mass spectrometry. | Yakimavets V et al. | — | 2022 | → |
| Smokeless tobacco and cigarette smoking: chemical mechanisms and cancer prevention. | Hecht SS et al. | — | 2022 | → |
| Stimulus functions of nicotine. | LeSage MG | — | 2022 | → |
| Study on the effects of combined tea drinking and mental activity after dinner on smokers in China. | Chen Z et al. | — | 2022 | → |
| Tetraspanin CD9: A friend or foe of head and neck cancer (Review). | P C S et al. | — | 2022 | → |
| The association between cotinine-measured smoking intensity and sleep quality. | Oh S et al. | — | 2022 | → |
| The 'Danse Macabre'-Neutrophils the Interactive Partner Affecting Oral Cancer Outcomes. | Hadjigol S et al. | — | 2022 | → |
| The Differential Effects of Chronic Alcohol and Cigarette Smoke Exposures on Cognitive-Behavioral Dysfunction in Long Evans Rats. | Yalcin EB et al. | — | 2022 | → |
| The Influence of Smoking on Renal Functions Among Apparently Healthy Smokers. | Eid HA et al. | — | 2022 | → |
| The involvement of mesolimbic dopamine system in cotinine self-administration in rats. | Tan X et al. | — | 2022 | → |
| The potential role of nicotine in breast cancer initiation, development, angiogenesis, invasion, metastasis, and resistance to therapy. | Khodabandeh Z et al. | — | 2022 | → |
| The prevalence, mechanism of action, and toxicity of Nigerian psychoactive plants. | Fasakin OW et al. | — | 2022 | → |
| The price of nicotine dependence: A comparison of the cost of nicotine across products in Switzerland, Germany, USA, Sweden, France and the UK, in 2019. | Jakob J et al. | — | 2022 | → |
| Tobacco Use Disorder. | Leone FT et al. | — | 2022 | → |
| Ultra-processed foods and allergic symptoms among children and adults in the United States: A population-based analysis of NHANES 2005-2006. | Kong W et al. | — | 2022 | → |
| Under lithium carbonate administration, nicotine triggers cell dysfunction in human glioblastoma U-251MG cells, which is distinct from cotinine. | Kato S | — | 2022 | → |
| Understanding the Interaction Between Prostaglandins and Toll-Like Receptors in Nicotine-Induced Rectal Tumor in Animals. | Peng W et al. | — | 2022 | → |
| Urinary Nicotine Metabolites and Self-Reported Tobacco Use Among Adults in the Population Assessment of Tobacco and Health (PATH) Study, 2013-2014. | Feng J et al. | — | 2022 | → |
| Analysis of Active and Passive Tobacco Exposures and Blood Pressure in US Children and Adolescents. | Levy RV et al. | — | 2021 | → |
| Applications of Adductomics in Chemically Induced Adverse Outcomes and Major Emphasis on DNA Adductomics: A Pathbreaking Tool in Biomedical Research. | Behl T et al. | — | 2021 | → |
| Association Between Body Weight and Telomere Length Is Predominantly Mediated Through C-Reactive Protein. | Gao X et al. | — | 2021 | → |
| Association between cotinine-verified smoking status and moderately increased albuminuria in the middle-aged and older population in Korea: A nationwide population-based study. | Choi Y et al. | — | 2021 | → |
| Association between Second-hand Smoke Exposure and Urinary NNAL Level in Korean Adolescents. | You HS et al. | — | 2021 | → |
| Associations between Second-Hand Tobacco Smoke Exposure and Cardiorespiratory Fitness, Physical Activity, and Respiratory Health in Children. | Parnell M et al. | — | 2021 | → |
| Attenuating nicotine's effects with high affinity human anti-nicotine monoclonal antibodies. | Raleigh MD et al. | — | 2021 | → |
| Automated Solid Phase Extraction and Polarity-Switching Tandem Mass Spectrometry Technique for High Throughput Analysis of Urine Biomarkers for 14 Tobacco-related Compounds. | Piyankarage SC et al. | — | 2021 | → |
| Biochemistry of nicotine metabolism and its relevance to lung cancer. | Murphy SE | — | 2021 | → |
| Chronic Obstructive Pulmonary Disease is a Risk Factor for Sensorineural Hearing Loss: A US Population Study. | Sharma RK et al. | — | 2021 | → |
| Clinical Pharmacology of Electronic Nicotine Delivery Systems (ENDS): Implications for Benefits and Risks in the Promotion of the Combusted Tobacco Endgame. | Benowitz NL et al. | — | 2021 | → |
| Comparative study of the effects of cigarette smoke versus next generation tobacco and nicotine product extracts on endothelial function. | Giebe S et al. | — | 2021 | → |
| Comparing cotinine and NNAL verification of self-reported smoking status among lung cancer screening eligible population from the 2007-2014 National Health and Nutrition Examination Survey (NHANES). | Li W et al. | — | 2021 | → |
| Comparing the Rate of Nicotine Metabolism Among Smokers With Current or Past Major Depressive Disorder. | Schnoll R et al. | — | 2021 | → |
| Comparison of tobacco use in a university town and a nearby urban area in China by intensive analysis of wastewater over one year period. | Wang Z et al. | — | 2021 | → |
| Concentrations of Cotinine and 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol (NNAL) in U.S. Non-Daily Cigarette Smokers. | Gutiérrez-Torres DS et al. | — | 2021 | → |
| Confronting Racism in Environmental Health Sciences: Moving the Science Forward for Eliminating Racial Inequities. | Payne-Sturges DC et al. | — | 2021 | → |
| Cotinine Hydroxylase CotA Initiates Biodegradation of Wastewater Micropollutant Cotinine in <i>Nocardioides</i> sp. Strain JQ2195. | Zhao L et al. | — | 2021 | → |
| Cotinine: Pharmacologically Active Metabolite of Nicotine and Neural Mechanisms for Its Actions. | Tan X et al. | — | 2021 | → |
| Decreased Levels of Soluble CD44 in a High-Risk Population following a Smoking Cessation Program. | Smith DH et al. | — | 2021 | → |
| Developing Analytical Applications for Parahydrogen Hyperpolarization: Urinary Elimination Pharmacokinetics of Nicotine. | Reimets N et al. | — | 2021 | → |
| Development of Machine Learning Models for Prediction of Smoking Cessation Outcome. | Lai CC et al. | — | 2021 | → |
| Diallyl disulfide prevents cigarette smoke-induced emphysema in mice. | Cardoso AOP et al. | — | 2021 | → |
| Does maternal exposure to nicotine affect the oocyte quality and reproductive capacity in adult offspring? | Paccola CC et al. | — | 2021 | → |
| Dysregulated Metabolites Serve as Novel Biomarkers for Metabolic Diseases Caused by E-Cigarette Vaping and Cigarette Smoking. | Wang Q et al. | — | 2021 | → |
| E-cigarette aerosols containing nicotine modulate nicotinic acetylcholine receptors and astroglial glutamate transporters in mesocorticolimbic brain regions of chronically exposed mice. | Alasmari F et al. | — | 2021 | → |
| E-Cigarettes as a Growing Threat for Children and Adolescents: Position Statement From the European Academy of Paediatrics. | Bush A et al. | — | 2021 | → |
| Effect of race and glucuronidation rates on the relationship between nicotine metabolite ratio and nicotine clearance. | Liakoni E et al. | — | 2021 | → |
| Enantioselectivity in Drug Pharmacokinetics and Toxicity: Pharmacological Relevance and Analytical Methods. | Coelho MM et al. | — | 2021 | → |
| Estimation of alcohol and nicotine consumption in 11 cities of Turkey using wastewater-based epidemiology. | Yavuz Guzel E et al. | — | 2021 | → |
| Evidence-based analysis of the effect of smoking on osseointegrated implant outcome. | Hadadi AA et al. | — | 2021 | → |
| Exposure to secondhand smoke is associated with increased left ventricular mass. | Skipina TM et al. | — | 2021 | → |
| Genetic Factors Associated with COPD Depend on the Ancestral Caucasian/Amerindian Component in the Mexican Population. | Pérez-Rubio G et al. | — | 2021 | → |
| Heritable consequences of paternal nicotine exposure: from phenomena to mechanisms†. | McCarthy DM et al. | — | 2021 | → |
| Household food insecurity and in-utero and early life smoke exposure: Data from NHANES 2003-2016. | Sanjeevi N et al. | — | 2021 | → |
| <i>In Vivo</i> Profiling of a Natural Alkaloid, Anatabine, in Rodents: Pharmacokinetics and Anti-Inflammatory Efficacy. | Xia W et al. | — | 2021 | → |
| Intermediate Effects of Body Mass Index and C-Reactive Protein on the Serum Cotinine- Leukocyte Telomere Length Association. | Gao X et al. | — | 2021 | → |
| Long-term electronic cigarette exposure induces cardiovascular dysfunction similar to tobacco cigarettes: role of nicotine and exposure duration. | El-Mahdy MA et al. | — | 2021 | → |
| Lung function, COPD and Alternative Healthy Eating Index in US adults. | Ducharme-Smith K et al. | — | 2021 | → |
| Molecular docking and oxidation kinetics of 3-phenyl coumarin derivatives by human CYP2A13. | Juvonen RO et al. | — | 2021 | → |
| Nicotine' actions on energy balance: Friend or foe? | Seoane-Collazo P et al. | — | 2021 | → |
| Nicotine e-cigarette vapor inhalation and self-administration in a rodent model: Sex- and nicotine delivery-specific effects on metabolism and behavior. | Lallai V et al. | — | 2021 | → |
| Nicotine Population Pharmacokinetics in Healthy Smokers After Intravenous, Oral, Buccal and Transdermal Administration. | Olsson Gisleskog PO et al. | — | 2021 | → |
| Nicotine self-administration with menthol and audiovisual cue facilitates differential packaging of CYP2A6 and cytokines/chemokines in rat plasma extracellular vesicles. | Kumar A et al. | — | 2021 | → |
| Physiologically Based Pharmacokinetic Modelling for Nicotine and Cotinine Clearance in Pregnant Women. | Amice B et al. | — | 2021 | → |
| Rapid, sensitive, and reliable quantitation of nicotine and its main metabolites cotinine and trans-3'-hydroxycotinine by LC-MS/MS: Method development and validation for human plasma. | Mallock N et al. | — | 2021 | → |
| Recent Developments in the Determination of Biomarkers of Tobacco Smoke Exposure in Biological Specimens: A Review. | Marques H et al. | — | 2021 | → |
| Responses to Gradual and Immediate Reduction of Nicotine in Cigarettes in Young Versus Older Adult Smokers. | Cassidy RN et al. | — | 2021 | → |
| Rodent models for nicotine withdrawal. | Chellian R et al. | — | 2021 | → |
| Secondhand Smoke Exposure is Associated with Prevalent Heart Failure: Longitudinal Examination of the National Health and Nutrition Examination Survey. | Skipina TM et al. | — | 2021 | → |
| Self-Administration of Cotinine in Wistar Rats: Comparisons to Nicotine. | Ding ZM et al. | — | 2021 | → |
| Sensitive Quantification of Nicotine in Bronchoalveolar Lavage Fluid by Acetone Precipitation Combined With Isotope-Dilution Liquid Chromatography-Tandem Mass Spectrometry. | Xia B et al. | — | 2021 | → |
| Simultaneous analysis of urinary total 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, N'-nitrosonornicotine, and cotinine by liquid chromatography-tandem mass-spectrometry. | Nikam SS et al. | — | 2021 | → |
| Smoking and income distribution: Inequalities in new and old products. | Carnazza G et al. | — | 2021 | → |
| Smoking cessation reduces systemic inflammation and circulating endothelin-1. | Derella CC et al. | — | 2021 | → |
| Smoking flies: testing the effect of tobacco cigarettes on heart function of <i>Drosophila melanogaster</i>. | Santalla M et al. | — | 2021 | → |
| Study protocol: evaluation of the addictive potential of e-cigarettes (EVAPE): neurobiological, sociological, and epidemiological perspectives. | Vollstädt-Klein S et al. | — | 2021 | → |
| Task-dependent effects of nicotine treatment on auditory performance in young-adult and elderly human nonsmokers. | Sun S et al. | — | 2021 | → |
| Testosterone Deficiency, Long-Term Testosterone Therapy, and Inflammation. | Zhang X et al. | — | 2021 | → |
| Tobacco-free Nicotine - New Name, Same Scheme? | Cwalina SN et al. | — | 2021 | → |
| Tobacco smoke exposure enhances reward sensitivity in male and female rats. | Chellian R et al. | — | 2021 | → |
| Tobacco Use and Periodontal Disease-The Role of Microvascular Dysfunction. | Silva H | — | 2021 | → |
| Toxicity of electronic cigarettes: A general review of the origins, health hazards, and toxicity mechanisms. | Cao Y et al. | — | 2021 | → |
| Tremor measurements in a 22-year cohort study of workers exposed to hand-held vibrating tools. | Bast-Pettersen R et al. | — | 2021 | → |
| Urinary Cotinine and Cotinine + Trans-3'-Hydroxycotinine (TNE-2) Cut-points for Distinguishing Tobacco Use from Nonuse in the United States: PATH Study (2013-2014). | Edwards KC et al. | — | 2021 | → |
| Alcohol, nicotine, and caffeine consumption on a public U.S. university campus determined by wastewater-based epidemiology. | Driver EM et al. | — | 2020 | → |
| A Machine-Learning Approach to Predicting Smoking Cessation Treatment Outcomes. | Coughlin LN et al. | — | 2020 | → |
| A Mobile Health Intervention for Adolescents Exposed to Secondhand Smoke: Pilot Feasibility and Efficacy Study. | Nardone N et al. | — | 2020 | → |
| Assessment of carcinogenic and toxic substances in <i>'Insunko'</i> herb. | Kalubula M et al. | — | 2020 | → |
| Bidirectional Associations among Nicotine and Tobacco Smoke, NeuroHIV, and Antiretroviral Therapy. | Ghura S et al. | — | 2020 | → |
| Biochemical Verification of Tobacco Use and Abstinence: 2019 Update. | Benowitz NL et al. | — | 2020 | → |
| Changes in Cigarette Consumption With Reduced Nicotine Content Cigarettes Among Smokers With Psychiatric Conditions or Socioeconomic Disadvantage: 3 Randomized Clinical Trials. | Higgins ST et al. | — | 2020 | → |
| Changes in Use Patterns Over 1 Year Among Smokers and Dual Users of Combustible and Electronic Cigarettes. | Piper ME et al. | — | 2020 | → |
| Chronic cigarette smoke exposure triggers a vicious cycle of leukocyte and endothelial-mediated oxidant stress that results in vascular dysfunction. | El-Mahdy MA et al. | — | 2020 | → |
| Cognitive performance effects of nicotine and industry affiliation: a systematic review. | Pasetes SV et al. | — | 2020 | → |
| Comparison of Liquid Chromatography Mass Spectrometry and Enzyme-Linked Immunosorbent Assay Methods to Measure Salivary Cotinine Levels in Ill Children. | Mahabee-Gittens EM et al. | — | 2020 | → |
| Comprehensive Parent-Metabolite PBPK/PD Modeling Insights into Nicotine Replacement Therapy Strategies. | Kovar L et al. | — | 2020 | → |
| Coumarin-Based Profluorescent and Fluorescent Substrates for Determining Xenobiotic-Metabolizing Enzyme Activities In Vitro. | Raunio H et al. | — | 2020 | → |
| Cytotoxic and genotoxic evaluation of cotinine using human neuroblastoma cells (SH-SY5Y). | Dalberto D et al. | — | 2020 | → |
| Designing around Structural Alerts in Drug Discovery. | Kalgutkar AS | — | 2020 | → |
| Design, rationale, and baseline characteristics of a pilot randomized clinical trial of nicotine treatment for pulmonary sarcoidosis. | Hade EM et al. | — | 2020 | → |
| Differences in nicotine intake and effects from electronic and combustible cigarettes among dual users. | St Helen G et al. | — | 2020 | → |
| Does second-hand smoke associate with tooth loss among older Japanese? JAGES cross-sectional study. | Umemori S et al. | — | 2020 | → |
| Electronic cigarette exposure disrupts blood-brain barrier integrity and promotes neuroinflammation. | Heldt NA et al. | — | 2020 | → |
| Environmental exposures and health behavior in association with mental health: a study design. | Hautekiet P et al. | — | 2020 | → |
| Evaluation of the distribution of nicotine intravenous injection: an adult autopsy case report with a review of literature. | Aoki Y et al. | — | 2020 | → |
| Exposure to a Tobacco-Specific Carcinogen Among Adolescent Smokeless Tobacco Users in Rural California, United States. | Chaffee BW et al. | — | 2020 | → |
| First nation-wide estimation of tobacco consumption in Spain using wastewater-based epidemiology. | Montes R et al. | — | 2020 | → |
| High throughput bar adsorptive microextraction: A simple and effective analytical approach for the determination of nicotine and cotinine in urine samples. | Ahmad SM et al. | — | 2020 | → |
| How bad are e-cigarettes? What can we learn from animal exposure models? | Marczylo T | — | 2020 | → |
| <i>In vivo</i> assessment of genotoxic potential of brown shammah (smokeless tobacco) in bone marrow cells of mice. | Tripathi P et al. | — | 2020 | → |
| Impact of Menthol on Oral Nicotine Consumption in Female and Male Sprague Dawley Rats. | Bagdas D et al. | — | 2020 | → |
| Impact of smoking on metabolic changes and effectiveness of drugs used for lung cancer. | Perlík F | — | 2020 | → |
| Independent and Combined Effects of Nicotine or Chronic Tobacco Smoking and HIV on the Brain: A Review of Preclinical and Clinical Studies. | Chang L et al. | — | 2020 | → |
| Inhibition and induction of CYP enzymes in humans: an update. | Hakkola J et al. | — | 2020 | → |
| Is there enough evidence to classify cycloalkyl amine substituents as structural alerts? | Kalgutkar AS et al. | — | 2020 | → |
| <i>UGT2B10</i> Genotype Influences Serum Cotinine Levels and Is a Primary Determinant of Higher Cotinine in African American Smokers. | Sipe CJ et al. | — | 2020 | → |
| Lung cancer in women in 21th century. | Domagala-Kulawik J et al. | — | 2020 | → |
| Maternal Tobacco Smoke Exposure Causes Sex-Divergent Changes in Placental Lipid Metabolism in the Rat. | Weinheimer C et al. | — | 2020 | → |
| Mechanisms of Herb-Drug Interactions Involving Cinnamon and CYP2A6: Focus on Time-Dependent Inhibition by Cinnamaldehyde and 2-Methoxycinnamaldehyde. | Espiritu MJ et al. | — | 2020 | → |
| Metabolites of Tobacco- and E-Cigarette-Related Nitrosamines Can Drive Cu<sup>2+</sup>-Mediated DNA Oxidation. | Kankanamage RNT et al. | — | 2020 | → |
| Method development and validation of dissolution testing for nicotine release from smokeless tobacco products using flow-through cell apparatus and UPLC-PDA. | Miller JH et al. | — | 2020 | → |
| More than Smoke and Patches: The Quest for Pharmacotherapies to Treat Tobacco Use Disorder. | Moerke MJ et al. | — | 2020 | → |
| Nicotine and Its Downstream Metabolites in Maternal and Cord Sera: Biomarkers of Prenatal Smoking Exposure Associated with Offspring DNA Methylation. | Kheirkhah Rahimabad P et al. | — | 2020 | → |
| Nicotine enhances auditory processing in healthy and normal-hearing young adult nonsmokers. | Pham CQ et al. | — | 2020 | → |
| Nicotine exposure increases markers of oxidant stress in stored red blood cells from healthy donor volunteers. | Stefanoni D et al. | — | 2020 | → |
| Nicotine in Senescence and Atherosclerosis. | Centner AM et al. | — | 2020 | → |
| Opportunities for evaluating chemical exposures and child health in the United States: the Environmental influences on Child Health Outcomes (ECHO) Program. | Buckley JP et al. | — | 2020 | → |
| [Physiological and Psychological Data influencing Pregnant Women Smoking Behavior - CNGOF-SFT Expert Report and Guidelines for Smoking Management during Pregnancy]. | Berveiller P et al. | — | 2020 | → |
| Pleiotropic Functions of Cytochrome P450 Monooxygenase-Derived Eicosanoids in Cancer. | Luo Y et al. | — | 2020 | → |
| Predicting bone turnover following tobacco exposure using bone alkaline phosphatase and N-telopeptide biomarkers and possible variability and effect modification of these markers by race/ethnicity. | Omoike OE et al. | — | 2020 | → |
| Pyrrolidinyl Synthetic Cathinones α-PHP and 4F-α-PVP Metabolite Profiling Using Human Hepatocyte Incubations. | Carlier J et al. | — | 2020 | → |
| Quantitative prediction of human pharmacokinetic responses to drugs via fluidically coupled vascularized organ chips. | Herland A et al. | — | 2020 | → |
| Recent Updates on Obesity Treatments: Available Drugs and Future Directions. | Dragano NRV et al. | — | 2020 | → |
| Reprint of: Recent Updates on Obesity Treatments: Available Drugs and Future Directions. | Dragano NRV et al. | — | 2020 | → |
| Secondhand smoke exposure and higher blood pressure in children and adolescents participating in NHANES. | Liu SH et al. | — | 2020 | → |
| Smokeless tobacco induced biophysical and biochemical alterations in the plasma, erythrocytes, and platelets of panmasala users: Subsequent biological effects. | Begum SF et al. | — | 2020 | → |
| Sources and Biomarkers of Secondhand Tobacco Smoke Exposure in Urban Adolescents. | Nardone N et al. | — | 2020 | → |
| The Impact of Sex on Changes in Plasma Corticosterone and Cotinine Levels Induced by Nicotine in C57BL/6J Mice. | Nguyen K et al. | — | 2020 | → |
| Therapeutic approaches to cholinergic deficiency in Lewy body diseases. | Barrett MJ et al. | — | 2020 | → |
| The Use of the Nicotine Metabolite Ratio as a Biomarker to Personalize Smoking Cessation Treatment: Current Evidence and Future Directions. | Siegel SD et al. | — | 2020 | → |
| Tiron protects against nicotine-induced lung and liver injury through antioxidant and anti-inflammatory actions in rats in vivo. | Khaled S et al. | — | 2020 | → |
| Urine Metabolites for Estimating Daily Intake of Nicotine From Cigarette Smoking. | Benowitz NL et al. | — | 2020 | → |
| Use of a physiologically-based pharmacokinetic model to explore the potential disparity in nicotine disposition between adult and adolescent nonhuman primates. | Yang X et al. | — | 2020 | → |
| Using wastewater-based epidemiology to estimate consumption of alcohol and nicotine in major cities of China in 2014 and 2016. | Gao J et al. | — | 2020 | → |
| Waterpipe (hookah) tobacco use in pregnancy: use, preferences and perceptions of flavours. | Stroud L et al. | — | 2020 | → |
| A biomonitoring assessment of secondhand exposures to electronic cigarette emissions. | Johnson JM et al. | — | 2019 | → |
| Alcohol and nicotine consumption trends in three U.S. communities determined by wastewater-based epidemiology. | Chen J et al. | — | 2019 | → |
| Aldehyde oxidase and its role as a drug metabolizing enzyme. | Dalvie D et al. | — | 2019 | → |
| A mouse model for chronic intermittent electronic cigarette exposure exhibits nicotine pharmacokinetics resembling human vapers. | Shao XM et al. | — | 2019 | → |
| Analyzing the pathways enriched in genes associated with nicotine dependence in the context of human protein-protein interaction network. | Hu Y et al. | — | 2019 | → |
| Betel quid containing safrole enhances metabolic activation of tobacco specific 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). | Tsou HH et al. | — | 2019 | → |
| Black Light Smokers: How Nicotine Intake and Carcinogen Exposure Differ Across Various Biobehavioral Factors. | St Helen G et al. | — | 2019 | → |
| Brief Report: Rate of Nicotine Metabolism and Tobacco Use Among Persons With HIV: Implications for Treatment and Research. | Schnoll RA et al. | — | 2019 | → |
| Central nicotine induces browning through hypothalamic κ opioid receptor. | Seoane-Collazo P et al. | — | 2019 | → |
| Chemical Biomarkers of Exposure and Early Damage from Potentially Carcinogenic Airborne Pollutants. | Luo K et al. | — | 2019 | → |
| Chronic Cigarette Smoking Associates Directly and Indirectly with Self-Reported Olfactory Alterations: Analysis of the 2011-2014 National Health and Nutrition Examination Survey. | Glennon SG et al. | — | 2019 | → |
| Chronic intermittent electronic cigarette exposure induces cardiac dysfunction and atherosclerosis in apolipoprotein-E knockout mice. | Espinoza-Derout J et al. | — | 2019 | → |
| Comprehensive Chemical Characterization of Natural American Spirit Cigarettes. | Jain V et al. | — | 2019 | → |
| Differences in the rate of nicotine metabolism among smokers with and without HIV. | Ashare RL et al. | — | 2019 | → |
| Dual Users Compared to Smokers: Demographics, Dependence, and Biomarkers. | Piper ME et al. | — | 2019 | → |
| E-cigarettes and Western Diet: Important Metabolic Risk Factors for Hepatic Diseases. | Hasan KM et al. | — | 2019 | → |
| Effect of Cigarette Rod Length on Smokers Switching to SPECTRUM Cigarettes. | Hrabovsky SM et al. | — | 2019 | → |
| Effect of GAD1 genotype status on auditory attention and acute nicotine administration in healthy volunteers. | Hadjis E et al. | — | 2019 | → |
| Effects of nicotine on rat adrenal gland: crosstalk between oxidative and inflammatory markers, and amelioration by melatonin. | Abdel Fattah S et al. | — | 2019 | → |
| Efflux transport of nicotine, cotinine and trans-3'-hydroxycotinine glucuronides by human hepatic transporters. | Järvinen E et al. | — | 2019 | → |
| Epigenome-wide association study of serum cotinine in current smokers reveals novel genetically driven loci. | Gupta R et al. | — | 2019 | → |
| Evaluation of the Cascade of Diabetes Care in the United States, 2005-2016. | Kazemian P et al. | — | 2019 | → |
| Evidence for respiratory viruses interactions in asymptomatic preschool-aged children. | Douros K et al. | — | 2019 | → |
| Glutathione <i>S</i>-Transferase Genotype Protects against <i>In Utero</i> Tobacco-linked Lung Function Deficits. | Owens L et al. | — | 2019 | → |
| High Content Screening in NHBE cells shows significantly reduced biological activity of flavoured e-liquids, when compared to cigarette smoke condensate. | Czekala L et al. | — | 2019 | → |
| Induction via Functional Protein Stabilization of Hepatic Cytochromes P450 upon gp78/Autocrine Motility Factor Receptor (AMFR) Ubiquitin E3-Ligase Genetic Ablation in Mice: Therapeutic and Toxicological Relevance. | Kwon D et al. | — | 2019 | → |
| In times of tobacco-free nicotine consumption: The influence of nicotine on vascular calcification. | Babic M et al. | — | 2019 | → |
| MicroRNA expression profiling of nicotine-treated human periodontal ligament cells. | Du A et al. | — | 2019 | → |
| Mitochondria as a possible target for nicotine action. | Malińska D et al. | — | 2019 | → |
| Molecular and health effects in the upper respiratory tract associated with tobacco smoking other than cigarettes. | Szyfter K et al. | — | 2019 | → |
| Neurobiological and Neurophysiological Mechanisms Underlying Nicotine Seeking and Smoking Relapse. | Schmidt HD et al. | — | 2019 | → |
| Nicotine Bitartrate Reduces Falls and Freezing of Gait in Parkinson Disease: A Reanalysis. | Lieberman A et al. | — | 2019 | → |
| Nicotine increased VEGF and MMP2 levels in the rat eye and kidney. | Ates M et al. | — | 2019 | → |
| Nicotine-induced oxidative stress contributes to EMT and stemness during neoplastic transformation through epigenetic modifications in human kidney epithelial cells. | Chang YW et al. | — | 2019 | → |
| Nicotine-Induced Oxidative Stress in Human Primary Endometrial Cells. | Khademi F et al. | — | 2019 | → |
| Nicotine Induces Resistance to Erlotinib Therapy in Non-Small-Cell Lung Cancer Cells Treated with Serum from Human Patients. | Imabayashi T et al. | — | 2019 | → |
| Nicotine-<i>N</i>'-Oxidation by Flavin Monooxygenase Enzymes. | Perez-Paramo YX et al. | — | 2019 | → |
| Nicotine levels in silicone wristband samplers worn by children exposed to secondhand smoke and electronic cigarette vapor are highly correlated with child's urinary cotinine. | Quintana PJE et al. | — | 2019 | → |
| Nicotine oxidation by genetic variants of CYP2B6 and in human brain microsomes. | Bloom AJ et al. | — | 2019 | → |
| Nicotine Pharmacokinetics in Rat Brain and Blood by Simultaneous Microdialysis, Stable-Isotope Labeling, and UHPLC-HRMS: Determination of Nicotine Metabolites. | Xu Y et al. | — | 2019 | → |
| Not all smokers appear to seek nicotine for the same reasons: implications for preclinical research in nicotine dependence. | Garcia-Rivas V et al. | — | 2019 | → |
| Optimization of a nicotine degrading enzyme for potential use in treatment of nicotine addiction. | Thisted T et al. | — | 2019 | → |
| Pharmacological identification of cholinergic receptor subtypes: modulation of locomotion and neural circuit excitability in Drosophila larvae. | Malloy CA et al. | — | 2019 | → |
| Pregnancy-Induced Increases in the Nicotine Metabolite Ratio: Examining Changes During Antepartum and Postpartum. | Arger CA et al. | — | 2019 | → |
| Preliminary investigation of acaricidal activity of leaf extract of <i>Nicotiana tabacum</i> on dog tick <i>Rhipicephalus sanguineus</i>. | Oyagbemi TO et al. | — | 2019 | → |
| Relationship between skin melanin index and nicotine pharmacokinetics in African American smokers. | Liakoni E et al. | — | 2019 | → |
| Smoking and urinary cotinine by socioeconomic status in the Heinz Nixdorf Recall Study. | Hovanec J et al. | — | 2019 | → |
| The relationship between nicotine metabolism and nicotine and carcinogen exposure among American Indian commercial cigarette smokers and electronic nicotine delivery system users. | Carroll DM et al. | — | 2019 | → |
| Tobacco and Pituri Use in Pregnancy: A Protocol for Measuring Maternal and Perinatal Exposure and Outcomes in Central Australian Aboriginal Women. | Ratsch A et al. | — | 2019 | → |
| Transcriptome analysis of genes and metabolic pathways associated with nicotine degradation in Aspergillus oryzae 112822. | He C et al. | — | 2019 | → |
| Transforming brain signals related to value evaluation and self-control into behavioral choices. | Zha R et al. | — | 2019 | → |
| Trends in nicotine consumption between 2010 and 2017 in an Australian city using the wastewater-based epidemiology approach. | Mackie RS et al. | — | 2019 | → |
| Validity of Commonly Used Heart Rate Variability Markers of Autonomic Nervous System Function. | Thomas BL et al. | — | 2019 | → |
| What is the nicotine delivery profile of electronic cigarettes? | Voos N et al. | — | 2019 | → |
| Young adults report increased pleasure from using e-cigarettes and smoking tobacco cigarettes when drinking alcohol. | Thrul J et al. | — | 2019 | → |
| A comprehensive methodology for the chiral separation of 40 tobacco alkaloids and their carcinogenic E/Z-(R,S)-tobacco-specific nitrosamine metabolites. | Hellinghausen G et al. | — | 2018 | → |
| A computerized exposure system for animal models to optimize nicotine delivery into the brain through inhalation of electronic cigarette vapors or cigarette smoke. | Alasmari F et al. | — | 2018 | → |
| Adolescent smokers' response to reducing the nicotine content of cigarettes: Acute effects on withdrawal symptoms and subjective evaluations. | Cassidy RN et al. | — | 2018 | → |
| Association of internal smoking dose with blood DNA methylation in three racial/ethnic populations. | Park SL et al. | — | 2018 | → |
| Biomarkers of Exposure to Secondhand and Thirdhand Tobacco Smoke: Recent Advances and Future Perspectives. | Torres S et al. | — | 2018 | → |
| Chronic intermittent nicotine delivery via lung alveolar region-targeted aerosol technology produces circadian pharmacokinetics in rats resembling human smokers. | Shao XM et al. | — | 2018 | → |
| Chronic nicotine exposure reduces klotho expression and triggers different renal and hemodynamic responses in klotho-haploinsufficient mice. | Coelho FO et al. | — | 2018 | → |
| Cigarette consumption and biomarkers of nicotine exposure during pregnancy and postpartum. | Taghavi T et al. | — | 2018 | → |
| Cigarette Filter Ventilation and Smoking Protocol Influence Aldehyde Smoke Yields. | Pauwels CGGM et al. | — | 2018 | → |
| Cigarette smoking is associated with an altered vaginal tract metabolomic profile. | Nelson TM et al. | — | 2018 | → |
| Comparison of Urine 4-(Methylnitrosamino)-1-(3)Pyridyl-1-Butanol and Cotinine for Assessment of Active and Passive Smoke Exposure in Urban Adolescents. | Benowitz NL et al. | — | 2018 | → |
| Contaminants of emerging concern: Nicotine in wastewater as a public health analysis tool. | de Granda-Orive JI et al. | — | 2018 | → |
| Current Evidence on Dental Implants Outcomes in Smokers and Nonsmokers: A Systematic Review and Meta-Analysis. | Alfadda SA | — | 2018 | → |
| CYP2A6 metabolism in the development of smoking behaviors in young adults. | Olfson E et al. | — | 2018 | → |
| Cytochrome P450 in Pharmacogenetics: An Update. | Tornio A et al. | — | 2018 | → |
| Cytochrome P450: Polymorphisms and Roles in Cancer, Diabetes and Atherosclerosis | Elfaki I et al. | — | 2018 | → |
| Dermal uptake of nicotine from air and clothing: Experimental verification. | Bekö G et al. | — | 2018 | → |
| Dose Response and Prediction Characteristics of a Methylation Sensitive Digital PCR Assay for Cigarette Consumption in Adults. | Philibert R et al. | — | 2018 | → |
| Duration-dependent effects of nicotine exposure on growth and AKT activation in human kidney epithelial cells. | Chang YW et al. | — | 2018 | → |
| E-cigarettes: Impact of E-Liquid Components and Device Characteristics on Nicotine Exposure. | DeVito EE et al. | — | 2018 | → |
| Effect of overnight smoking abstinence on a marker for microglial activation: a [<sup>11</sup>C]DAA1106 positron emission tomography study. | Brody AL et al. | — | 2018 | → |
| Evaluation of E-Vapor Nicotine and Nicotyrine Concentrations under Various E-Liquid Compositions, Device Settings, and Vaping Topographies. | Son Y et al. | — | 2018 | → |
| Green Tobacco Sickness among Brazilian farm workers and genetic polymorphisms. | da Mota E Silva MS et al. | — | 2018 | → |
| Incidence of Lung Cancer among Young Women. | Al-Kindi S et al. | — | 2018 | → |
| Incidence of Lung Cancer among Young Women. | Berlin I | — | 2018 | → |
| Incidence of Lung Cancer among Young Women. | Funatogawa I | — | 2018 | → |
| Incidence of Lung Cancer among Young Women. | Jemal A et al. | — | 2018 | → |
| Investigating the relationships among neighborhood factors and asthma control in African American children: A study protocol. | DePriest K et al. | — | 2018 | → |
| In vitro-in vivo correlations for nicotine transdermal delivery systems evaluated by both in vitro skin permeation (IVPT) and in vivo serum pharmacokinetics under the influence of transient heat application. | Shin SH et al. | — | 2018 | → |
| Isolation and characterization of the cotinine-degrading bacterium Nocardioides sp. Strain JQ2195. | Qiu J et al. | — | 2018 | → |
| Longitudinal Influence of Pregnancy on Nicotine Metabolic Pathways. | Taghavi T et al. | — | 2018 | → |
| Mechanisms of toxicity and biomarkers of flavoring and flavor enhancing chemicals in emerging tobacco and non-tobacco products. | Kaur G et al. | — | 2018 | → |
| Molecular Insights Into Memory-Enhancing Metabolites of Nicotine in Brain: A Systematic Review. | Majdi A et al. | — | 2018 | → |
| Nicotine delivery efficiency of first- and second-generation e-cigarettes and its impact on relief of craving during the acute phase of use. | Rüther T et al. | — | 2018 | → |
| Nicotine dependence is associated with functional variation in FMO3, an enzyme that metabolizes nicotine in the brain. | Teitelbaum AM et al. | — | 2018 | → |
| Nicotine enhances mesangial cell proliferation and fibronectin production in high glucose milieu via activation of Wnt/β-catenin pathway. | Lan X et al. | — | 2018 | → |
| Nicotine Intake in Pregnant Smokers and a General Population of Smokers. | Berlin I et al. | — | 2018 | → |
| Nicotine Metabolism-informed Care for Smoking Cessation: A Pilot Precision RCT. | Wells QS et al. | — | 2018 | → |
| Nicotine metabolite ratio and smoking outcomes using nicotine replacement therapy and varenicline among smokers with and without psychiatric illness. | Clyde M et al. | — | 2018 | → |
| Nicotine reduces effectiveness of doxorubicin chemotherapy and promotes CD44<sup>+</sup>CD24<sup>-</sup> cancer stem cells in MCF-7 cell populations. | Türker Şener L et al. | — | 2018 | → |
| Occurrence and distribution of carbamazepine, nicotine, estrogenic compounds, and their transformation products in wastewater from various treatment plants and the aquatic environment. | Ekpeghere KI et al. | — | 2018 | → |
| Oral cancer and tobacco: developments in harm reduction. | Pemberton MN | — | 2018 | → |
| Orally administered nicotine effects on rat urinary bladder proliferation and carcinogenesis. | Suzuki S et al. | — | 2018 | → |
| P450 Pharmacogenetics in Indigenous North American Populations. | Henderson LM et al. | — | 2018 | → |
| Pharmacokinetic Evaluation of Two Nicotine Patches in Smokers. | Rasmussen S et al. | — | 2018 | → |
| Prevalence and factors associated with self-reported chronic obstructive pulmonary disease among adults aged 40-79: the National Health and Nutrition Examination Survey (NHANES) 2007-2012. | Tilert T et al. | — | 2018 | → |
| Self-reported prenatal tobacco smoke exposure, AXL gene-body methylation, and childhood asthma phenotypes. | Gao L et al. | — | 2018 | → |
| Serum metabolites are associated with all-cause mortality in chronic kidney disease. | Hu JR et al. | — | 2018 | → |
| Single-Dose Bioequivalence of Two Mini Nicotine Lozenge Formulations. | Rasmussen SC et al. | — | 2018 | → |
| Smoking and Incident Hypertension - Importance of Cotinine-Verified Smoking Status. | Ebina T | — | 2018 | → |
| The contribution of agonist and antagonist activities of α4β2* nAChR ligands to smoking cessation efficacy: a quantitative analysis of literature data. | Rollema H et al. | — | 2018 | → |
| The effects of electronic cigarette vapour on the lung: direct comparison to tobacco smoke. | Reinikovaite V et al. | — | 2018 | → |
| The metabolic fate of dietary nicotine in the cabbage looper, Trichoplusia ni (Hübner). | Saremba BM et al. | — | 2018 | → |
| The nicotine-degrading enzyme NicA2 reduces nicotine levels in blood, nicotine distribution to brain, and nicotine discrimination and reinforcement in rats. | Pentel PR et al. | — | 2018 | → |
| The Role of <i>CYP2A6</i> Genetic Polymorphism in Nicotine Dependence and Tobacco Consumption among Bataknese Male Smokers. | Soeroso NN et al. | — | 2018 | → |
| Tobacco biomarkers and genetic/epigenetic analysis to investigate ethnic/racial differences in lung cancer risk among smokers. | Murphy SE et al. | — | 2018 | → |
| Tobacco smoke exposure is an independent predictor of vitamin D deficiency in US children. | Nwosu BU et al. | — | 2018 | → |
| Tracking narcotics consumption at a Southwestern U.S. university campus by wastewater-based epidemiology. | Gushgari AJ et al. | — | 2018 | → |
| Transdermal Nicotine for the Treatment of Mood and Cognitive Symptoms in Nonsmokers With Late-Life Depression. | Gandelman JA et al. | — | 2018 | → |
| Urine Cotinine level with smoking history predicts a risk of coronary artery calcification. | Yu HJ et al. | — | 2018 | → |
| Vascular component of hand-arm vibration syndrome: a 22-year follow-up study. | Aarhus L et al. | — | 2018 | → |
| Age-dependent sensitivity of the mouse kidney to chronic nicotine exposure. | Arany I et al. | — | 2017 | → |
| A prenatal nicotine exposure mouse model of methylphenidate responsive ADHD-associated cognitive phenotypes. | Zhu J et al. | — | 2017 | → |
| Association between cotinine-verified smoking status and hypertension in 167,868 Korean adults. | Kim BJ et al. | — | 2017 | → |
| Association of CYP2A6 activity with lung cancer incidence in smokers: The multiethnic cohort study. | Park SL et al. | — | 2017 | → |
| Behavioral changes after nicotine challenge are associated with α7 nicotinic acetylcholine receptor-stimulated glutamate release in the rat dorsal striatum. | Ryu IS et al. | — | 2017 | → |
| Biomarkers of exposure to new and emerging tobacco delivery products. | Schick SF et al. | — | 2017 | → |
| Biomarkers of Tobacco Exposure: Summary of an FDA-Sponsored Public Workshop. | Chang CM et al. | — | 2017 | → |
| Cardiovascular effects of electronic cigarettes. | Benowitz NL et al. | — | 2017 | → |
| Characterization and Genome Analysis of a Nicotine and Nicotinic Acid-Degrading Strain Pseudomonas putida JQ581 Isolated from Marine. | Li A et al. | — | 2017 | → |
| Coenzyme Q10 protects renal proximal tubule cells against nicotine-induced apoptosis through induction of p66<sup>shc</sup>-dependent antioxidant responses. | Arany I et al. | — | 2017 | → |
| CYP2A6 genetic polymorphisms and biomarkers of tobacco smoke constituents in relation to risk of lung cancer in the Singapore Chinese Health Study. | Yuan JM et al. | — | 2017 | → |
| Detoxification and elimination of nicotine by nectar-feeding birds. | Lerch-Henning S et al. | — | 2017 | → |
| Disruption of retinal pigment epithelial cell properties under the exposure of cotinine. | Zhang XY et al. | — | 2017 | → |
| Distribution of polymorphic variants of CYP2A6 and their involvement in nicotine addiction. | López-Flores LA et al. | — | 2017 | → |
| Does coffee consumption impact on heaviness of smoking? | Ware JJ et al. | — | 2017 | → |
| Effect of nicotine on the proliferation and chondrogenic differentiation of the human Wharton's jelly mesenchymal stem cells. | Yang X et al. | — | 2017 | → |
| Effect of UGT2B10, UGT2B17, FMO3, and OCT2 genetic variation on nicotine and cotinine pharmacokinetics and smoking in African Americans. | Taghavi T et al. | — | 2017 | → |
| Effects of 6-Week Use of Reduced-Nicotine Content Cigarettes in Smokers With and Without Elevated Depressive Symptoms. | Tidey JW et al. | — | 2017 | → |
| Effects of chronic inhalation of electronic cigarettes containing nicotine on glial glutamate transporters and α-7 nicotinic acetylcholine receptor in female CD-1 mice. | Alasmari F et al. | — | 2017 | → |
| Effects of Nicotine Metabolites on Nicotine Withdrawal Behaviors in Mice. | Elhassan S et al. | — | 2017 | → |
| Estimating population size in wastewater-based epidemiology. Valencia metropolitan area as a case study. | Rico M et al. | — | 2017 | → |
| Expression Changes of Apoptotic Genes in Tissues from Mice Exposed to Nicotine | Jalili C et al. | — | 2017 | → |
| Fetal exposure to tobacco: nicotine and cotinine concentration in amniotic fluid and maternal saliva. | Jacob N et al. | — | 2017 | → |
| Gender and Racial/Ethnic Disparities: Cumulative Screening of Health Risk Indicators in 20-50 Year Olds in the United States. | Cordner A et al. | — | 2017 | → |
| Genetic polymorphisms in CYP2A6 are associated with a risk of cigarette smoking and predispose to smoking at younger ages. | Pérez-Rubio G et al. | — | 2017 | → |
| Hepatic transcriptomic profiles from barramundi, Lates calcarifer, as a means of assessing organism health and identifying stressors in rivers in northern Queensland. | Hook SE et al. | — | 2017 | → |
| How people think about the chemicals in cigarette smoke: a systematic review. | Morgan JC et al. | — | 2017 | → |
| Impact of e-liquid flavors on nicotine intake and pharmacology of e-cigarettes. | St Helen G et al. | — | 2017 | → |
| Increased HPA Axis Activity and Serum Tryptophan in Naswar (Dipping Tobacco) Users: A Case-Control Study. | Sajid F et al. | — | 2017 | → |
| Influence of alpha-lipoic acid on nicotine-induced lung and liver damage in experimental rats. | Ateyya H et al. | — | 2017 | → |
| Inhalation of Alcohol Vapor: Measurement and Implications. | MacLean RR et al. | — | 2017 | → |
| Inhaled nicotine equivalent to cigarette smoking disrupts systemic and uterine hemodynamics and induces cardiac arrhythmia in pregnant rats. | Shao XM et al. | — | 2017 | → |
| In-utero exposure to nicotine alters the development of the rabbit cardiac conduction system and provides a potential mechanism for sudden infant death syndrome. | Ton AT et al. | — | 2017 | → |
| Investigating nutrition and lifestyle factors as determinants of abdominal obesity: an environment-wide study. | Wulaningsih W et al. | — | 2017 | → |
| In vitro human epidermal permeation of nicotine from electronic cigarette refill liquids and implications for dermal exposure assessment. | Frasch HF et al. | — | 2017 | → |
| Locus-specific DNA methylation in the placenta is associated with levels of pro-inflammatory proteins in cord blood and they are both independently affected by maternal smoking during pregnancy. | van Otterdijk SD et al. | — | 2017 | → |
| Low Cotinine Glucuronidation Results in Higher Serum and Saliva Cotinine in African American Compared to White Smokers. | Murphy SE et al. | — | 2017 | → |
| Measurements of dermal uptake of nicotine directly from air and clothing. | Bekö G et al. | — | 2017 | → |
| Measuring biomarkers in wastewater as a new source of epidemiological information: Current state and future perspectives. | Gracia-Lor E et al. | — | 2017 | → |
| Metabolomic Fingerprinting in Various Body Fluids of a Diet-Controlled Clinical Smoking Cessation Study Using a Validated GC-TOF-MS Metabolomics Platform. | Goettel M et al. | — | 2017 | → |
| Methyl mercury, but not inorganic mercury, associated with higher blood pressure during pregnancy. | Wells EM et al. | — | 2017 | → |
| Nicotine disrupts safety learning by enhancing fear associated with a safety cue via the dorsal hippocampus. | Connor DA et al. | — | 2017 | → |
| Nicotine Metabolism and Smoking: Ethnic Differences in the Role of P450 2A6. | Murphy SE | — | 2017 | → |
| Nicotine pharmacokinetic profiles of the Tobacco Heating System 2.2, cigarettes and nicotine gum in Japanese smokers. | Brossard P et al. | — | 2017 | → |
| Nicotine Population Pharmacokinetics in Healthy Adult Smokers: A Retrospective Analysis. | Marchand M et al. | — | 2017 | → |
| Nicotine Promotes Cholangiocarcinoma Growth in Xenograft Mice. | Martínez AK et al. | — | 2017 | → |
| Nicotine: Sporting Friend or Foe? A Review of Athlete Use, Performance Consequences and Other Considerations. | Mündel T | — | 2017 | → |
| Nicotinic receptors modulate the onset of reactive oxygen species production and mitochondrial dysfunction evoked by glutamate uptake block in the rat hypoglossal nucleus. | Tortora M et al. | — | 2017 | → |
| Non-smoking pregnant women and their fetuses are exposed to environmental tobacco smoke as a result of living in multiunit housing. | Orazine CI et al. | — | 2017 | → |
| One-Shot In Vitro Evolution Generated an Antibody Fragment for Testing Urinary Cotinine with More Than 40-Fold Enhanced Affinity. | Oyama H et al. | — | 2017 | → |
| Oral Cell DNA Adducts as Potential Biomarkers for Lung Cancer Susceptibility in Cigarette Smokers. | Hecht SS | — | 2017 | → |
| Pharmacokinetics of nicotine following the controlled use of a prototype novel tobacco vapor product. | Yuki D et al. | — | 2017 | → |
| Population pharmacokinetic model of transdermal nicotine delivered from a matrix-type patch. | Linakis MW et al. | — | 2017 | → |
| Precision medicine and pharmacogenetics: what does oncology have that addiction medicine does not? | Kranzler HR et al. | — | 2017 | → |
| Predictors of Variation in CYP2A6 mRNA, Protein, and Enzyme Activity in a Human Liver Bank: Influence of Genetic and Nongenetic Factors. | Tanner JA et al. | — | 2017 | → |
| Programmable carbon nanotube membrane-based transdermal nicotine delivery with microdialysis validation assay. | Gulati GK et al. | — | 2017 | → |
| Proteomic and metabolomic analysis reveals rapid and extensive nicotine detoxification ability in honey bee larvae. | du Rand EE et al. | — | 2017 | → |
| The Combination of Alcohol and Cigarette Smoke Induces Endoplasmic Reticulum Stress and Cell Death in Pancreatic Acinar Cells. | Lugea A et al. | — | 2017 | → |
| The discriminative stimulus effects of i.v. nicotine in rhesus monkeys: Pharmacokinetics and apparent pA<sub>2</sub> analysis with dihydro-β-erythroidine. | Moerke MJ et al. | — | 2017 | → |
| The effects of smoking and nicotine ingestion on exercise heat tolerance. | Druyan A et al. | — | 2017 | → |
| The metabolic fate of nectar nicotine in worker honey bees. | du Rand EE et al. | — | 2017 | → |
| The Role of Nitrosamine (NNK) in Breast Cancer Carcinogenesis. | Gankhuyag N et al. | — | 2017 | → |
| Toxicity of the main electronic cigarette components, propylene glycol, glycerin, and nicotine, in Sprague-Dawley rats in a 90-day OECD inhalation study complemented by molecular endpoints. | Phillips B et al. | — | 2017 | → |
| Tremor and hand-arm vibration syndrome (HAVS) in road maintenance workers. | Bast-Pettersen R et al. | — | 2017 | → |
| Trends in Environmental Tobacco Smoke (ETS) Exposure and Preterm Birth: Use of Smoking Bans and Direct ETS Exposure Assessments in Study Designs. | Elkin ER et al. | — | 2017 | → |
| Urinary Concentrations of Parabens and Other Antimicrobial Chemicals and Their Association with Couples' Fecundity. | Smarr MM et al. | — | 2017 | → |
| Urine Cotinine Screening Detects Nearly Ubiquitous Tobacco Smoke Exposure in Urban Adolescents. | Benowitz NL et al. | — | 2017 | → |
| Validation of an Arabic version of an instrument to measure waterpipe smoking behavior. | Abou Arbid S et al. | — | 2017 | → |
| Variation in CYP2A6 Activity and Personalized Medicine. | Tanner JA et al. | — | 2017 | → |
| A fully validated LC-MS/MS method for simultaneous determination of nicotine and its metabolite cotinine in human serum and its application to a pharmacokinetic study after using nicotine transdermal delivery systems with standard heat application in adult smokers. | Abdallah IA et al. | — | 2016 | → |
| Agmatine protects rat liver from nicotine-induced hepatic damage via antioxidative, antiapoptotic, and antifibrotic pathways. | El-Sherbeeny NA et al. | — | 2016 | → |
| An Inventory of Methods for the Assessment of Additive Increased Addictiveness of Tobacco Products. | van de Nobelen S et al. | — | 2016 | → |
| A simple physiologically based pharmacokinetic model evaluating the effect of anti-nicotine antibodies on nicotine disposition in the brains of rats and humans. | Saylor K et al. | — | 2016 | → |
| Assessing exposure to tobacco-specific carcinogen NNK using its urinary metabolite NNAL measured in US population: 2011-2012. | Wei B et al. | — | 2016 | → |
| Association between direct and indirect smoking and osteoarthritis prevalence in Koreans: a cross-sectional study. | Kang K et al. | — | 2016 | → |
| Association of Perfluoroalkyl Substances, Bone Mineral Density, and Osteoporosis in the U.S. Population in NHANES 2009-2010. | Khalil N et al. | — | 2016 | → |
| Biomonitoring of tobacco smoke exposure and self-reported smoking status among general population of Tehran, Iran. | Hoseini M et al. | — | 2016 | → |
| Caffeine plus nicotine improves motor function, spatial and non-spatial working memory and functional indices in BALB/c male mice. | Adeniyi PA et al. | — | 2016 | → |
| Cessation of alcohol consumption decreases rate of nicotine metabolism in male alcohol-dependent smokers. | Gubner NR et al. | — | 2016 | → |
| Chronic Nicotine Exposure Abolishes Maternal Systemic and Renal Adaptations to Pregnancy in Rats. | Ferreira VM et al. | — | 2016 | → |
| Cigarette smoking behaviour and blood metabolomics. | Gu F et al. | — | 2016 | → |
| Clinical Laboratory Evaluation of Electronic Cigarettes/Electronic Nicotine Delivery Systems: Methodological Challenges. | Blank MD et al. | — | 2016 | → |
| Comparative risk assessment of tobacco smoke constituents using the margin of exposure approach: the neglected contribution of nicotine. | Baumung C et al. | — | 2016 | → |
| Comprehensive review of epidemiological and animal studies on the potential carcinogenic effects of nicotine per se. | Haussmann HJ et al. | — | 2016 | → |
| Cord Blood Methylmercury and Fetal Growth Outcomes in Baltimore Newborns: Potential Confounding and Effect Modification by Omega-3 Fatty Acids, Selenium, and Sex. | Wells EM et al. | — | 2016 | → |
| Curcumin improves liver damage in male mice exposed to nicotine. | Salahshoor M et al. | — | 2016 | → |
| Developing a model of limited-access nicotine consumption in C57Bl/6J mice. | Kasten CR et al. | — | 2016 | → |
| Differences in cardiovascular toxicities associated with cigarette smoking and snuff use revealed using novel zebrafish models. | Folkesson M et al. | — | 2016 | → |
| Disposition kinetics and metabolism of nicotine and cotinine in African American smokers: impact of CYP2A6 genetic variation and enzymatic activity. | Benowitz NL et al. | — | 2016 | → |
| Does acute tobacco smoking prevent cue-induced craving? | Schlagintweit HE et al. | — | 2016 | → |
| [Efficacy and security of electronic cigarette for tobacco harm reduction: Systematic review and meta-analysis]. | Vanderkam P et al. | — | 2016 | → |
| Elevated blood lead and cadmium levels associated with chronic infections among non-smokers in a cross-sectional analysis of NHANES data. | Krueger WS et al. | — | 2016 | → |
| Estimations and predictors of non-compliance in switchers to reduced nicotine content cigarettes. | Nardone N et al. | — | 2016 | → |
| Evaluation of the Tobacco Heating System 2.2. Part 6: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of a mentholated version compared with mentholated and non-mentholated cigarette smoke. | Oviedo A et al. | — | 2016 | → |
| Exploratory analysis of the potential relationship between urinary molybdenum and bone mineral density among adult men and women from NHANES 2007-2010. | Lewis RC et al. | — | 2016 | → |
| Genetic determinants of CYP2A6 activity across racial/ethnic groups with different risks of lung cancer and effect on their smoking intensity. | Park SL et al. | — | 2016 | → |
| Genetic determinants of cytochrome P450 2A6 activity and biomarkers of tobacco smoke exposure in relation to risk of lung cancer development in the Shanghai cohort study. | Yuan JM et al. | — | 2016 | → |
| Genome-Wide Association of the Laboratory-Based Nicotine Metabolite Ratio in Three Ancestries. | Baurley JW et al. | — | 2016 | → |
| Genome-Wide Meta-Analysis of Cotinine Levels in Cigarette Smokers Identifies Locus at 4q13.2. | Ware JJ et al. | — | 2016 | → |
| High-fat diet meal patterns during and after continuous nicotine treatment in male rats. | Mendez IA et al. | — | 2016 | → |
| Interactive effects of maternal cigarette smoke, heat stress, hypoxia, and lipopolysaccharide on neonatal cardiorespiratory and cytokine responses. | McDonald FB et al. | — | 2016 | → |
| Intravenous and oral suicidal e-liquid poisonings with confirmed nicotine and cotinine concentrations. | Sommerfeld K et al. | — | 2016 | → |
| In vivo modulation of the behavioral effects of nicotine by the coumarins xanthotoxin, bergapten, and umbelliferone. | Budzynska B et al. | — | 2016 | → |
| Late reproductive analysis in rat male offspring exposed to nicotine during pregnancy and lactation. | Miranda-Spooner M et al. | — | 2016 | → |
| Metabolic Pathways and Networks Associated With Tobacco Use in Military Personnel. | Jones DP et al. | — | 2016 | → |
| Nicotine and Cotinine Levels With Electronic Cigarette: A Review. | Marsot A et al. | — | 2016 | → |
| Nicotine Delivery and Vaping Behavior During <i>ad Libitum</i> E-cigarette Access. | St Helen G et al. | — | 2016 | → |
| Nicotine delivery, retention and pharmacokinetics from various electronic cigarettes. | St Helen G et al. | — | 2016 | → |
| Nicotine Dependence and Urinary Nicotine, Cotinine and Hydroxycotinine Levels in Daily Smokers. | Van Overmeire IP et al. | — | 2016 | → |
| Nicotine Enhances High-Fat Diet-Induced Oxidative Stress in the Kidney. | Arany I et al. | — | 2016 | → |
| Nicotine-Induced Apoptosis in Human Renal Proximal Tubular Epithelial Cells. | Kim CS et al. | — | 2016 | → |
| Nicotine Metabolism in Young Adult Daily Menthol and Nonmenthol Smokers. | Fagan P et al. | — | 2016 | → |
| Pharmacokinetic Drug Interactions with Tobacco, Cannabinoids and Smoking Cessation Products. | Anderson GD et al. | — | 2016 | → |
| Pharmacological identification of cholinergic receptor subtypes on Drosophila melanogaster larval heart. | Malloy CA et al. | — | 2016 | → |
| Precision Medicine for Tobacco Dependence: Development and Validation of the Nicotine Metabolite Ratio. | Allenby CE et al. | — | 2016 | → |
| Protocol for study of financial incentives for smoking cessation in pregnancy (FISCP): randomised, multicentre study. | Berlin N et al. | — | 2016 | → |
| Pu-erh Tea Extract Attenuates Nicotine-Induced Foam Cell Formation in Primary Cultured Monocytes: An in Vitro Mechanistic Study. | Tu SH et al. | — | 2016 | → |
| Quantitation of the Minor Tobacco Alkaloids Nornicotine, Anatabine, and Anabasine in Smokers' Urine by High Throughput Liquid Chromatography-Mass Spectrometry. | von Weymarn LB et al. | — | 2016 | → |
| Racial differences in the relationship between rate of nicotine metabolism and nicotine intake from cigarette smoking. | Ross KC et al. | — | 2016 | → |
| Second-hand smoke exposure in 4-year-old children in Spain: Sources, associated factors and urinary cotinine. | Aurrekoetxea JJ et al. | — | 2016 | → |
| Secretome analysis of human articular chondrocytes unravels catabolic effects of nicotine on the joint. | Lourido L et al. | — | 2016 | → |
| Smokescreen: a targeted genotyping array for addiction research. | Baurley JW et al. | — | 2016 | → |
| Smoking, second-hand smoke exposure and smoking cessation in relation to leukocyte telomere length and mortality. | Wulaningsih W et al. | — | 2016 | → |
| Structural Analysis Provides Mechanistic Insight into Nicotine Oxidoreductase from Pseudomonas putida. | Tararina MA et al. | — | 2016 | → |
| Temporal Trends of Secondhand Smoke Exposure: Nonsmoking Workers in the United States (NHANES 2001-2010). | Wei B et al. | — | 2016 | → |
| The pro-oxidant gene p66shc increases nicotine exposure-induced lipotoxic oxidative stress in renal proximal tubule cells. | Arany I et al. | — | 2016 | → |
| The separate and combined effects of monoamine oxidase A inhibition and nicotine on resting state EEG. | Smith DM et al. | — | 2016 | → |
| Three Decades of High-Dose Nicotine Gum Dependence Treated With Nicotine Patches. | Mendelsohn CP | — | 2016 | → |
| Tobacco smoking and breastfeeding: Effect on the lactation process, breast milk composition and infant development. A critical review. | Napierala M et al. | — | 2016 | → |
| Urinary paracetamol and time-to-pregnancy. | Smarr MM et al. | — | 2016 | → |
| A Genome-Wide Association Study of a Biomarker of Nicotine Metabolism. | Loukola A et al. | — | 2015 | → |
| A High Throughput Method for Estimating Mouth-Level Intake of Mainstream Cigarette Smoke. | Yan X et al. | — | 2015 | → |
| Ameliorative effect of chronic moderate exercise in smoke exposed or nicotine applied rats from acute stress. | Kuru P et al. | — | 2015 | → |
| A novel approach for monitoring tobacco use in local communities by wastewater analysis. | Castiglioni S et al. | — | 2015 | → |
| Association between urinary biomarkers of exposure to organophosphate insecticides and serum reproductive hormones in men from NHANES 1999-2002. | Omoike OE et al. | — | 2015 | → |
| Association of CYP2A6 gene polymorphisms with cigarette consumption: a meta-analysis. | Pan L et al. | — | 2015 | → |
| Associations Between Genetic Ancestries and Nicotine Metabolism Biomarkers in the Multiethnic Cohort Study. | Wang H et al. | — | 2015 | → |
| Biochemical estimation of noncompliance with smoking of very low nicotine content cigarettes. | Benowitz NL et al. | — | 2015 | → |
| Biomarkers of exposure to molybdenum and other metals in relation to testosterone among men from the United States National Health and Nutrition Examination Survey 2011-2012. | Lewis RC et al. | — | 2015 | → |
| Biomarkers of Response to Smoking Cessation Pharmacotherapies: Progress to Date. | Mamoun M et al. | — | 2015 | → |
| Biomarkers of tobacco smoke exposure in racial/ethnic groups at high risk for lung cancer. | Fagan P et al. | — | 2015 | → |
| Cadmium levels in a North Carolina cohort: Identifying risk factors for elevated levels during pregnancy. | Edwards SE et al. | — | 2015 | → |
| CHRNA3 rs6495308 genotype as an effect modifier of the association between daily cigarette consumption and hypertension in Chinese male smokers. | Wu XY et al. | — | 2015 | → |
| Combined analysis of the tobacco metabolites cotinine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in human urine. | Kotandeniya D et al. | — | 2015 | → |
| Comparison of Regional Brain Perfusion Levels in Chronically Smoking and Non-Smoking Adults. | Durazzo TC et al. | — | 2015 | → |
| Composition of betel specific chemicals in saliva during betel chewing for the identification of biomarkers. | Franke AA et al. | — | 2015 | → |
| COMT polymorphism modulates the resting-state EEG alpha oscillatory response to acute nicotine in male non-smokers. | Bowers H et al. | — | 2015 | → |
| Cotinine as a marker for risk prediction in the Ludwigshafen Risk and Cardiovascular Health Study. | Delgado G et al. | — | 2015 | → |
| Curcumin protects against nicotine-induced stress during protein malnutrition in female rat through immunomodulation with cellular amelioration. | Maiti M et al. | — | 2015 | → |
| CYP2A6 Polymorphisms May Strengthen Individualized Treatment for Nicotine Dependence. | Akrodou YM | — | 2015 | → |
| Detoxification mechanisms of honey bees (Apis mellifera) resulting in tolerance of dietary nicotine. | Rand EED et al. | — | 2015 | → |
| Development of a Novel Oral Cavity Compartmental Absorption and Transit Model for Sublingual Administration: Illustration with Zolpidem. | Xia B et al. | — | 2015 | → |
| Diversity of native nicotinic receptor subtypes in mammalian brain. | Zoli M et al. | — | 2015 | → |
| Effects of cigarette smoking and nicotine metabolite ratio on leukocyte telomere length. | Verde Z et al. | — | 2015 | → |
| Effects of different routes of nicotine administration on gastric morphology and hormonal secretion in rats. | Ali SS et al. | — | 2015 | → |
| Electronic cigarettes: The nicotyrine hypothesis. | Abramovitz A et al. | — | 2015 | → |
| Gelsolin is a potential cellular target for cotinine to regulate the migration and apoptosis of A549 and T24 cancer cells. | Nowak JM et al. | — | 2015 | → |
| Gender differences in cadmium and cotinine levels in prepubertal children. | Fucic A et al. | — | 2015 | → |
| Haemodynamic responses to tobacco smoke inhalation in male adolescents in Lusaka, Zambia. | Chikopela T et al. | — | 2015 | → |
| Homozygous deletions of UGT2B17 modifies effects of smoking on TP53-mutations and relapse of head and neck carcinoma. | Mafune A et al. | — | 2015 | → |
| Identification and characterization of in vitro and in vivo metabolites of steroidal alkaloid veratramine. | Lyu C et al. | — | 2015 | → |
| Large Variation in Brain Exposure of Reference CNS Drugs: a PET Study in Nonhuman Primates. | Schou M et al. | — | 2015 | → |
| Levels of nicotine in Ethiopian tobacco leaves. | Tassew Z et al. | — | 2015 | → |
| Maternal Smokeless Tobacco Use in Pregnancy and Adverse Health Outcomes in Newborns: A Systematic Review. | Inamdar AS et al. | — | 2015 | → |
| Mercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer. | Park SL et al. | — | 2015 | → |
| Mismatch negativity in tobacco-naïve cannabis users and its alteration with acute nicotine administration. | Impey D et al. | — | 2015 | → |
| N-acetyltransferase 1 polymorphism increases cotinine levels in Caucasian children exposed to secondhand smoke: the CCAAPS birth cohort. | LeMasters GK et al. | — | 2015 | → |
| National monitoring of nicotine use in Czech and Slovak Republic based on wastewater analysis. | Mackuľak T et al. | — | 2015 | → |
| New Insights into the Mechanisms of Action of Cotinine and its Distinctive Effects from Nicotine. | Grizzell JA et al. | — | 2015 | → |
| Nicotine and cotinine exposure from electronic cigarettes: a population approach. | Vélez de Mendizábal N et al. | — | 2015 | → |
| Nicotine: Carcinogenicity and Effects on Response to Cancer Treatment - A Review. | Sanner T et al. | — | 2015 | → |
| Nicotine induces resistance to erlotinib via cross-talk between α 1 nAChR and EGFR in the non-small cell lung cancer xenograft model. | Li H et al. | — | 2015 | → |
| Nicotine in high concentration causes contraction of isolated strips of rabbit corpus cavernosum. | Nguyen HB et al. | — | 2015 | → |
| Nicotine intake from electronic cigarettes on initial use and after 4 weeks of regular use. | Hajek P et al. | — | 2015 | → |
| Nicotine metabolite ratio (3-hydroxycotinine/cotinine) in plasma and urine by different analytical methods and laboratories: implications for clinical implementation. | Tanner JA et al. | — | 2015 | → |
| Nicotine molecularly imprinted polymer: synergy of coordination and hydrogen bonding. | Huynh TP et al. | — | 2015 | → |
| Nicotine reinforcement in never-smokers. | Duke AN et al. | — | 2015 | → |
| Nicotine stimulates expression of proteins implicated in peripheral and central sensitization. | Hawkins JL et al. | — | 2015 | → |
| Nicotinic, glutamatergic and dopaminergic synaptic transmission and plasticity in the mesocorticolimbic system: focus on nicotine effects. | Pistillo F et al. | — | 2015 | → |
| NIH electronic cigarette workshop: developing a research agenda. | Walton KM et al. | — | 2015 | → |
| Not only smoking is deadly: fatal ingestion of e-juice-a case report. | Bartschat S et al. | — | 2015 | → |
| Nuciferine, extracted from Nelumbo nucifera Gaertn, inhibits tumor-promoting effect of nicotine involving Wnt/β-catenin signaling in non-small cell lung cancer. | Liu W et al. | — | 2015 | → |
| On-Line Chemical Composition Analysis of Refillable Electronic Cigarette Aerosol-Measurement of Nicotine and Nicotyrine. | Martinez RE et al. | — | 2015 | → |
| Pharmacokinetics of cotinine in rats: a potential therapeutic agent for disorders of cognitive function. | Li P et al. | — | 2015 | → |
| Protective Role of Crocin Against Nicotine-induced Damages on Male Mice Liver. | Jalili C et al. | — | 2015 | → |
| Quantification of plasma microRNAs in a group of healthy smokers, ex-smokers and non-smokers and correlation to biomarkers of tobacco exposure. | Banerjee A et al. | — | 2015 | → |
| Quantitative analysis of 3'-hydroxynorcotinine in human urine. | Upadhyaya P et al. | — | 2015 | → |
| Randomized Trial of Reduced-Nicotine Standards for Cigarettes. | Donny EC et al. | — | 2015 | → |
| R-(+) and S-(-) isomers of cotinine augment cholinergic responses in vitro and in vivo. | Terry AV et al. | — | 2015 | → |
| Simultaneous quantification of tobacco alkaloids and major phase I metabolites by LC-MS/MS in human tissue. | Fischer L et al. | — | 2015 | → |
| Smokeless tobacco consumption impedes metabolic, cellular, apoptotic and systemic stress pattern: A study on Government employees in Kolkata, India. | Biswas S et al. | — | 2015 | → |
| Synergistic Impact of Nicotine and Shear Stress Induces Cytoskeleton Collapse and Apoptosis in Endothelial Cells. | Lee YH et al. | — | 2015 | → |
| The clinical significance and reliability of self-reported smoking status in patients with intracranial aneurysms: a review. | Davis MC et al. | — | 2015 | → |
| The contribution of common genetic variation to nicotine and cotinine glucuronidation in multiple ethnic/racial populations. | Patel YM et al. | — | 2015 | → |
| The impact of active and former smoking on the severity of obstructive sleep apnea. | Varol Y et al. | — | 2015 | → |
| The Nicotine Metabolite Ratio in Pregnancy Measured by trans-3'-Hydroxycotinine to Cotinine Ratio: Characteristics and Relationship With Smoking Cessation. | Vaz LR et al. | — | 2015 | → |
| The Reinforcing Effects of Nicotine in Humans and Nonhuman Primates: A Review of Intravenous Self-Administration Evidence and Future Directions for Research. | Goodwin AK et al. | — | 2015 | → |
| The reply. | Orellana-Barrios MA et al. | — | 2015 | → |
| The separate and combined effects of monoamine oxidase A inhibition and nicotine on the mismatch negativity event related potential. | Smith DM et al. | — | 2015 | → |
| The separate and combined effects of monoamine oxidase inhibition and nicotine on P50 sensory gating. | Smith DM et al. | — | 2015 | → |
| Time-course of extracellular nicotine and cotinine levels in rat brain following administration of nicotine: effects of route and ethanol coadministration. | Katner SN et al. | — | 2015 | → |
| Tobacco smoking during pregnancy and risk of adverse behaviour in offspring: A follow-up study. | Dürr DW et al. | — | 2015 | → |
| Transdermal patches: history, development and pharmacology. | Pastore MN et al. | — | 2015 | → |
| UGT1A and UGT2B genetic variation alters nicotine and nitrosamine glucuronidation in european and african american smokers. | Wassenaar CA et al. | — | 2015 | → |
| Urinary cotinine levels and environmental tobacco smoke in mothers and children of Romania, Portugal and Poland within the European human biomonitoring pilot study. | Lupsa IR et al. | — | 2015 | → |
| Usual intake of added sugars and lipid profiles among the U.S. adolescents: National Health and Nutrition Examination Survey, 2005-2010. | Zhang Z et al. | — | 2015 | → |
| Validation of a Respiratory Symptom Questionnaire in Adolescent Smokers. | Cassidy RN et al. | — | 2015 | → |
| Wastewater analysis to monitor use of caffeine and nicotine and evaluation of their metabolites as biomarkers for population size assessment. | Senta I et al. | — | 2015 | → |
| α-Tocopherol protects renal cells from nicotine- or oleic acid-provoked oxidative stress via inducing heme oxygenase-1. | Reed DK et al. | — | 2015 | → |
| Acute electronic cigarette use: nicotine delivery and subjective effects in regular users. | Dawkins L et al. | — | 2014 | → |
| A high-throughput robotic sample preparation system and HPLC-MS/MS for measuring urinary anatabine, anabasine, nicotine and major nicotine metabolites. | Wei B et al. | — | 2014 | → |
| A novel mechanism for nicotinic potentiation of glutamatergic synapses. | Halff AW et al. | — | 2014 | → |
| Assessment of local tobacco consumption by liquid chromatography-tandem mass spectrometry sewage analysis of nicotine and its metabolites, cotinine and trans-3'-hydroxycotinine, after enzymatic deconjugation. | Rodríguez-Álvarez T et al. | — | 2014 | → |
| Association between bisphenol A and waist-to-height ratio among children: National Health and Nutrition Examination Survey, 2003-2010. | Wells EM et al. | — | 2014 | → |
| Baseline-dependent modulating effects of nicotine on voluntary and involuntary attention measured with brain event-related P3 potentials. | Knott V et al. | — | 2014 | → |
| Binding free energies for nicotine analogs inhibiting cytochrome P450 2A6 by a combined use of molecular dynamics simulations and QM/MM-PBSA calculations. | Lu H et al. | — | 2014 | → |
| Cannabis smoking and respiratory health: consideration of the literature. | Gates P et al. | — | 2014 | → |
| Chemical hazards present in liquids and vapors of electronic cigarettes. | Hutzler C et al. | — | 2014 | → |
| Chromatographic resolution of closely related species: drug metabolites and analogs. | Regalado EL et al. | — | 2014 | → |
| Clinical pharmacology research strategy for dissolvable tobacco products. | Mishina EV et al. | — | 2014 | → |
| Connections of nicotine to cancer. | Grando SA | — | 2014 | → |
| Determination of cotinine by LC-MS-MS with automated solid-phase extraction. | Dunlop AJ et al. | — | 2014 | → |
| Determining the causes and consequences of nicotine dependence: emerging genetic research methods. | Ware JJ et al. | — | 2014 | → |
| Direct action and modulating effect of (+)- and (-)-nicotine on ion channels expressed in trigeminal sensory neurons. | Schreiner BS et al. | — | 2014 | → |
| Do ethnicity and gender moderate the influence of posttraumatic stress disorder on time to smoking lapse? | Wilson SM et al. | — | 2014 | → |
| Drug abuse and the neurovascular unit. | Egleton RD et al. | — | 2014 | → |
| Effects of cigarette smoking on metabolism and effectiveness of systemic therapy for lung cancer. | O'Malley M et al. | — | 2014 | → |
| Electronic cigarettes and nicotine clinical pharmacology. | Schroeder MJ et al. | — | 2014 | → |
| Factors affecting the development of adverse drug reactions (Review article). | Alomar MJ | — | 2014 | → |
| Fatal intravenous injection of electronic nicotine delivery system refilling solution. | Thornton SL et al. | — | 2014 | → |
| Finding genomic function for genetic associations in nicotine addiction research: the ENCODE project's role in future pharmacogenomic analysis. | Vandenbergh DJ et al. | — | 2014 | → |
| Genetics and smoking. | Loukola A et al. | — | 2014 | → |
| High-performance liquid chromatography with diode-array detection cotinine method adapted for the assessment of tobacco smoke exposure. | Bartolomé M et al. | — | 2014 | → |
| How much nicotine kills a human? Tracing back the generally accepted lethal dose to dubious self-experiments in the nineteenth century. | Mayer B | — | 2014 | → |
| Influence of CYP2A6*4 genotypes on maternal serum cotinine among Chinese nonsmoking pregnant women. | Xie C et al. | — | 2014 | → |
| Influenza virus-induced lung inflammation was modulated by cigarette smoke exposure in mice. | Han Y et al. | — | 2014 | → |
| Inhibitory control dysfunction in nicotine dependence and the influence of short-term abstinence. | Charles-Walsh K et al. | — | 2014 | → |
| Inhibitory potency of 8-methoxypsoralen on cytochrome P450 2A6 (CYP2A6) allelic variants CYP2A6 15, CYP2A6 16, CYP2A6 21 and CYP2A6 22: differential susceptibility due to different sequence locations of the mutations. | Tiong KH et al. | — | 2014 | → |
| In vitro genoprotective and genotoxic effect of nicotine on human leukocytes evaluated by the comet assay. | Sobkowiak R et al. | — | 2014 | → |
| Maternal cadmium levels during pregnancy associated with lower birth weight in infants in a North Carolina cohort. | Johnston JE et al. | — | 2014 | → |
| Mechanisms of Cancer Induction by Tobacco-Specific NNK and NNN. | Xue J et al. | — | 2014 | → |
| Medical history, lifestyle, and occupational risk factors for hairy cell leukemia: the InterLymph Non-Hodgkin Lymphoma Subtypes Project. | Monnereau A et al. | — | 2014 | → |
| Metabolites of tobacco smoking and colorectal cancer risk. | Cross AJ et al. | — | 2014 | → |
| Modulation of auditory deviance detection by acute nicotine is baseline and deviant dependent in healthy nonsmokers: a mismatch negativity study. | Knott V et al. | — | 2014 | → |
| Multiresidue analysis of pesticides in urine of healthy adult companion dogs. | Forster GM et al. | — | 2014 | → |
| Natural history-driven, plant-mediated RNAi-based study reveals CYP6B46's role in a nicotine-mediated antipredator herbivore defense. | Kumar P et al. | — | 2014 | → |
| NeuroD1 mediates nicotine-induced migration and invasion via regulation of the nicotinic acetylcholine receptor subunits in a subset of neural and neuroendocrine carcinomas. | Osborne JK et al. | — | 2014 | → |
| Nicotine aversion: Neurobiological mechanisms and relevance to tobacco dependence vulnerability. | Fowler CD et al. | — | 2014 | → |
| Nicotine causes genotoxic damage but is not metabolized during long-term exposure of human nasal miniorgan cultures. | Ginzkey C et al. | — | 2014 | → |
| Nicotine derived genotoxic effects in human primary parotid gland cells as assessed in vitro by comet assay, cytokinesis-block micronucleus test and chromosome aberrations test. | Ginzkey C et al. | — | 2014 | → |
| Nicotine mediates hypochlorous acid-induced nuclear protein damage in mammalian cells. | Salama SA et al. | — | 2014 | → |
| Nicotine N-glucuronidation relative to N-oxidation and C-oxidation and UGT2B10 genotype in five ethnic/racial groups. | Murphy SE et al. | — | 2014 | → |
| Nicotine pharmacokinetics in rats is altered as a function of age, impacting the interpretation of animal model data. | Craig EL et al. | — | 2014 | → |
| Orally administered nicotine induces urothelial hyperplasia in rats and mice. | Dodmane PR et al. | — | 2014 | → |
| Pharmacogenetics of nicotine addiction: role of dopamine. | Herman AI et al. | — | 2014 | → |
| Pharmacological chaperoning of nAChRs: a therapeutic target for Parkinson's disease. | Srinivasan R et al. | — | 2014 | → |
| Plasma cotinine levels in cigarette smokers: impact of mental health and other correlates. | Bot M et al. | — | 2014 | → |
| Prolonged nicotine exposure down-regulates presynaptic NMDA receptors in dopaminergic terminals of the rat nucleus accumbens. | Salamone A et al. | — | 2014 | → |
| Relationship between cotinine and trans-3'-hydroxycotinine glucuronidation and the nicotine metabolite ratio in Caucasian smokers. | Jacobson GA et al. | — | 2014 | → |
| Simple, fast and sensitive LC-MS/MS analysis for the simultaneous quantification of nicotine and 10 of its major metabolites. | Piller M et al. | — | 2014 | → |
| Simultaneous multiplexed quantification of nicotine and its metabolites using surface enhanced Raman scattering. | Alharbi O et al. | — | 2014 | → |
| Smoking cessation. | Rennard SI et al. | — | 2014 | → |
| The acute effects of daily nicotine intake on heart rate--a toxicokinetic and toxicodynamic modelling study. | Gajewska M et al. | — | 2014 | → |
| The Genetics, Neurogenetics and Pharmacogenetics of Addiction. | Demers CH et al. | — | 2014 | → |
| Transgenerational transmission of hyperactivity in a mouse model of ADHD. | Zhu J et al. | — | 2014 | → |
| Urinary tobacco smoke-constituent biomarkers for assessing risk of lung cancer. | Yuan JM et al. | — | 2014 | → |
| Use of electronic cigarettes (e-cigarettes) impairs indoor air quality and increases FeNO levels of e-cigarette consumers. | Schober W et al. | — | 2014 | → |
| Validation of a LC-MS/MS method for quantifying urinary nicotine, six nicotine metabolites and the minor tobacco alkaloids--anatabine and anabasine--in smokers' urine. | McGuffey JE et al. | — | 2014 | → |
| Accentuating effects of nicotine on ethanol response in mice with high genetic predisposition to ethanol-induced locomotor stimulation. | Gubner NR et al. | — | 2013 | → |
| Age-related differences in the disposition of nicotine and metabolites in rat brain and plasma. | Vieira-Brock PL et al. | — | 2013 | → |
| A multi-route model of nicotine-cotinine pharmacokinetics, pharmacodynamics and brain nicotinic acetylcholine receptor binding in humans. | Teeguarden JG et al. | — | 2013 | → |
| Analysis of refill liquids for electronic cigarettes. | Etter JF et al. | — | 2013 | → |
| A review on renal toxicity profile of common abusive drugs. | Singh VP et al. | — | 2013 | → |
| Assessing secondhand smoke using biological markers. | Avila-Tang E et al. | — | 2013 | → |
| Assessment of changes in nicotine dependence, motivation, and symptoms of anxiety and depression among smokers in the initial process of smoking reduction or cessation: a short-term follow-up study. | Figueiró LR et al. | — | 2013 | → |
| Assessment of serum cotinine in patients with chronic heart failure: self-reported versus objective smoking behaviour. | Ebner N et al. | — | 2013 | → |
| Association between daily cigarette consumption and hypertension moderated by CYP2A6 genotypes in Chinese male current smokers. | Liu T et al. | — | 2013 | → |
| Baseline dependency of nicotine's sensory gating actions: similarities and differences in low, medium and high P50 suppressors. | Knott V et al. | — | 2013 | → |
| Biogenesis, trafficking and up-regulation of nicotinic ACh receptors. | Colombo SF et al. | — | 2013 | → |
| Blood cadmium is elevated in iron deficient U.S. children: a cross-sectional study. | Silver MK et al. | — | 2013 | → |
| Blood lead level association with lower body weight in NHANES 1999-2006. | Scinicariello F et al. | — | 2013 | → |
| Catalytic mechanism of cytochrome P450 for N-methylhydroxylation of nicotine: reaction pathways and regioselectivity of the enzymatic nicotine oxidation. | Li D et al. | — | 2013 | → |
| Chronic nicotine exposure and acute kidney injury: new concepts and experimental evidence. | Speeckaert MM et al. | — | 2013 | → |
| Chronic nicotine exposure stimulates biliary growth and fibrosis in normal rats. | Jensen K et al. | — | 2013 | → |
| Cloning of a novel nicotine oxidase gene from Pseudomonas sp. strain HZN6 whose product nonenantioselectively degrades nicotine to pseudooxynicotine. | Qiu J et al. | — | 2013 | → |
| Cotinine and trans 3'-hydroxycotinine in dried blood spots as biomarkers of tobacco exposure and nicotine metabolism. | Murphy SE et al. | — | 2013 | → |
| Current status on biochemistry and molecular biology of microbial degradation of nicotine. | Gurusamy R et al. | — | 2013 | → |
| CYP2A6 genotype but not age determines cotinine half-life in infants and children. | Dempsey DA et al. | — | 2013 | → |
| Deproteinized natural rubber film forming polymeric solutions for nicotine transdermal delivery. | Pichayakorn W et al. | — | 2013 | → |
| Development of a CD-MEKC method for investigating the metabolism of tamoxifen by flavin-containing monooxygenases and the inhibitory effects of methimazole, nicotine and DMXAA. | Yeniceli D et al. | — | 2013 | → |
| Direct quantitative analysis of nicotine alkaloids from biofluid samples using paper spray mass spectrometry. | Wang H et al. | — | 2013 | → |
| Dose-independent kinetics with low level exposure to nicotine and cotinine. | Benowitz NL et al. | — | 2013 | → |
| Effects of acute nicotine on prepulse inhibition of auditory change-related cortical responses. | Kodaira M et al. | — | 2013 | → |
| Effects of age on noninvasive assessments of vascular function in nonhuman primates: implications for translational drug discovery. | Knight DR et al. | — | 2013 | → |
| Effects of COMT genotype on sensory gating and its modulation by nicotine: Differences in low and high P50 suppressors. | de la Salle S et al. | — | 2013 | → |
| Effects of nicotine on electroencephalographic (EEG) and behavioural measures of visual working memory in non-smokers during a dual-task paradigm. | Fisher DJ et al. | — | 2013 | → |
| Effects of nicotine on visuospatial attentional orienting in non-smokers. | Impey D et al. | — | 2013 | → |
| Effects upon in-vivo nicotine metabolism reveal functional variation in FMO3 associated with cigarette consumption. | Bloom AJ et al. | — | 2013 | → |
| Escalating doses of transdermal nicotine in heavy smokers: effects on smoking behavior and craving. | Selby P et al. | — | 2013 | → |
| Explaining human recreational use of 'pesticides': The neurotoxin regulation model of substance use vs. the hijack model and implications for age and sex differences in drug consumption. | Hagen EH et al. | — | 2013 | → |
| Gene amplification and microsatellite polymorphism underlie a recent insect host shift. | Bass C et al. | — | 2013 | → |
| Genetic and pharmacokinetic determinants of response to transdermal nicotine in white, black, and Asian nonsmokers. | Dempsey DA et al. | — | 2013 | → |
| Good relationship between saliva cotinine kinetics and plasma cotinine kinetics after smoking one cigarette. | Yuki D et al. | — | 2013 | → |
| Hormonal regulation of hepatic drug biotransformation and transport systems. | Ruiz ML et al. | — | 2013 | → |
| Human brain functional network changes associated with enhanced and impaired attentional task performance. | Giessing C et al. | — | 2013 | → |
| Impact of nicotine metabolism on nicotine's pharmacological effects and behavioral responses: insights from a Cyp2a(4/5)bgs-null mouse. | Li L et al. | — | 2013 | → |
| Implicit and explicit reward learning in chronic nicotine use. | Paelecke-Habermann Y et al. | — | 2013 | → |
| In vitro particle size distributions in electronic and conventional cigarette aerosols suggest comparable deposition patterns. | Zhang Y et al. | — | 2013 | → |
| Methodologies for the quantitative estimation of toxicant dose to cigarette smokers using physical, chemical and bioanalytical data. | St Charles FK et al. | — | 2013 | → |
| Niccine®, a nicotine vaccine, for relapse prevention: a phase II, randomized, placebo-controlled, multicenter clinical trial. | Tonstad S et al. | — | 2013 | → |
| Nicotine and lung cancer. | Warren GW et al. | — | 2013 | → |
| Nicotine delivery to rats via lung alveolar region-targeted aerosol technology produces blood pharmacokinetics resembling human smoking. | Shao XM et al. | — | 2013 | → |
| Nicotine increases survival in human colon cancer cells treated with chemotherapeutic drugs. | Dinicola S et al. | — | 2013 | → |
| Nicotine metabolism and addiction among adolescent smokers. | Rubinstein ML et al. | — | 2013 | → |
| Nicotine related brain activity: the influence of smoking history and blood nicotine levels, an exploratory study. | Yamamoto RT et al. | — | 2013 | → |
| Nicotine signaling and progression of chronic kidney disease in smokers. | Jain G et al. | — | 2013 | → |
| Nornicotine nitrosation in saliva and its relation to endogenous synthesis of N'-nitrosonornicotine in humans. | Knezevich A et al. | — | 2013 | → |
| Parental and larval exposure to nicotine modulate spontaneous activity as well as cholinergic and GABA receptor expression in adult C. elegans. | Rose JK et al. | — | 2013 | → |
| Passive smoking induces leukotriene production in children: influence of asthma. | Hernández-Alvídrez E et al. | — | 2013 | → |
| Pharmacogenetic smoking cessation intervention in a health care setting: a pilot feasibility study. | McClure JB et al. | — | 2013 | → |
| Pharmacokinetic analysis of nicotine when using non-combustion inhaler type of tobacco product in Japanese adult male smokers. | Miura N et al. | — | 2013 | → |
| Presentation of smoking-associated cues does not elicit dopamine release after one-hour smoking abstinence: A [11C]-(+)-PHNO PET study. | Chiuccariello L et al. | — | 2013 | → |
| Race, gender, and nicotine metabolism in adolescent smokers. | Rubinstein ML et al. | — | 2013 | → |
| Serum cotinine levels and prehypertension in never smokers. | Alshaarawy O et al. | — | 2013 | → |
| Sex differences in nicotine self-administration in rats during progressive unit dose reduction: implications for nicotine regulation policy. | Grebenstein P et al. | — | 2013 | → |
| Simple and rapid assay method for simultaneous quantification of urinary nicotine and cotinine using micro-extraction by packed sorbent and gas chromatography-mass spectrometry. | Iwai M et al. | — | 2013 | → |
| Simultaneous serum nicotine, cotinine, and trans-3'-hydroxycotinine quantitation with minimal sample volume for tobacco exposure status of solid organ transplant patients. | Shu I et al. | — | 2013 | → |
| Stability of the nicotine metabolite ratio in smokers of progressively reduced nicotine content cigarettes. | St Helen G et al. | — | 2013 | → |
| Systems approaches evaluating the perturbation of xenobiotic metabolism in response to cigarette smoke exposure in nasal and bronchial tissues. | Iskandar AR et al. | — | 2013 | → |
| The ability of plasma cotinine to predict nicotine and carcinogen exposure is altered by differences in CYP2A6: the influence of genetics, race, and sex. | Zhu AZ et al. | — | 2013 | → |
| The contribution of common UGT2B10 and CYP2A6 alleles to variation in nicotine glucuronidation among European Americans. | Bloom AJ et al. | — | 2013 | → |
| The nicotine-mediated decline in l-dopa-induced dyskinesias is associated with a decrease in striatal dopamine release. | Bordia T et al. | — | 2013 | → |
| Thienopyridine efficacy and cigarette smoking status. | Bliden KP et al. | — | 2013 | → |
| Tobacco smoking effect on HIV-1 pathogenesis: role of cytochrome P450 isozymes. | Ande A et al. | — | 2013 | → |
| To what extent does adding tobacco to cannabis expose young users to nicotine? | Bélanger RE et al. | — | 2013 | → |
| Utility of urinary Clara cell protein (CC16) to demonstrate increased lung epithelial permeability in non-smokers exposed to outdoor secondhand smoke. | St Helen G et al. | — | 2013 | → |
| Variation in trans-3'-hydroxycotinine glucuronidation does not alter the nicotine metabolite ratio or nicotine intake. | Zhu AZ et al. | — | 2013 | → |
| β-cryptoxanthin restores nicotine-reduced lung SIRT1 to normal levels and inhibits nicotine-promoted lung tumorigenesis and emphysema in A/J mice. | Iskandar AR et al. | — | 2013 | → |
| 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone is correlated with 8-hydroxy-2'-deoxyguanosine in humans after exposure to environmental tobacco smoke. | Chiang HC et al. | — | 2012 | → |
| Accuracy of self-reported tobacco assessments in a head and neck cancer treatment population. | Warren GW et al. | — | 2012 | → |
| Activity change in response to bad air quality, National Health and Nutrition Examination Survey, 2007-2010. | Wells EM et al. | — | 2012 | → |
| Age-associated changes in nicotine dependence. | Park S et al. | — | 2012 | → |
| A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13. | Cho MH et al. | — | 2012 | → |
| Alcohol consumption effect on antiretroviral therapy and HIV-1 pathogenesis: role of cytochrome P450 isozymes. | Kumar S et al. | — | 2012 | → |
| Analysis of nicotine-induced DNA damage in cells of the human respiratory tract. | Ginzkey C et al. | — | 2012 | → |
| Associations of Cigarette Smoking and Polymorphisms in Brain-Derived Neurotrophic Factor and Catechol-O-Methyltransferase with Neurocognition in Alcohol Dependent Individuals during Early Abstinence. | Durazzo TC et al. | — | 2012 | → |
| Atomoxetine treatment for nicotine withdrawal: a pilot double-blind, placebo-controlled, fixed-dose study in adult smokers. | Silverstone PH et al. | — | 2012 | → |
| Cigarette smoking and chronic kidney diseases. | Nagasawa Y et al. | — | 2012 | → |
| CYP2A6- and CYP2A13-catalyzed metabolism of the nicotine Δ5'(1')iminium ion. | von Weymarn LB et al. | — | 2012 | → |
| Determination of tobacco smoke exposure by plasma cotinine levels in infants and children attending urban public hospital clinics. | Dempsey DA et al. | — | 2012 | → |
| Different binding modes of free and carrier-protein-coupled nicotine in a human monoclonal antibody. | Tars K et al. | — | 2012 | → |
| Differential effects of nicotine treatment and ethanol self-administration on CYP2A6, CYP2B6 and nicotine pharmacokinetics in African green monkeys. | Ferguson CS et al. | — | 2012 | → |
| Effects of acute nicotine administration on behavioral and neural (EEG) correlates of working memory in non-smokers. | Fisher DJ et al. | — | 2012 | → |
| Effects of acute nicotine on auditory change-related cortical responses. | Otsuru N et al. | — | 2012 | → |
| Emerging genetics of COPD. | Berndt A et al. | — | 2012 | → |
| Exposure to nicotine adversely affects the dendritic cell system and compromises host response to vaccination. | Nouri-Shirazi M et al. | — | 2012 | → |
| Gene-centric analysis of serum cotinine levels in African and European American populations. | Hamidovic A et al. | — | 2012 | → |
| General mechanisms of nicotine-induced fibrogenesis. | Jensen K et al. | — | 2012 | → |
| Glucuronidation of trans-3'-hydroxycotinine by UGT2B17 and UGT2B10. | Chen G et al. | — | 2012 | → |
| Impact of tobacco regulation on animal research: new perspectives and opportunities. | Donny EC et al. | — | 2012 | → |
| Inhibition and inactivation of cytochrome P450 2A6 and cytochrome P450 2A13 by menthofuran, β-nicotyrine and menthol. | Kramlinger VM et al. | — | 2012 | → |
| In vitro metabolic fate of alizapride: evidence for the formation of reactive metabolites based on liquid chromatography-tandem mass spectrometry. | Aprile S et al. | — | 2012 | → |
| Lung cancer in women. | Barrera-Rodriguez R et al. | — | 2012 | → |
| Mitigation by vitamin C of the genotoxic effects of nicotine in mice, assessed by the comet assay and micronucleus induction. | Kahl VF et al. | — | 2012 | → |
| Monoamine oxidase inhibitory activity in tobacco smoke varies with tobacco type. | Lewis AJ et al. | — | 2012 | → |
| Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone binding and access channel in human cytochrome P450 2A6 and 2A13 enzymes. | DeVore NM et al. | — | 2012 | → |
| Nicotine and the kidney: Mr. Hyde, and perhaps some Dr. Jekyll. | Budisavljevic MN et al. | — | 2012 | → |
| Nicotine, Auditory Sensory Memory, and sustained Attention in a Human Ketamine Model of Schizophrenia: Moderating Influence of a Hallucinatory Trait. | Knott V et al. | — | 2012 | → |
| Nicotine-induced chondrogenic differentiation of human bone marrow stromal cells in vitro. | Ying X et al. | — | 2012 | → |
| Nicotine intake and smoking topography in smokers with bipolar disorder. | Williams JM et al. | — | 2012 | → |
| Nicotine vaccines to assist with smoking cessation: current status of research. | Raupach T et al. | — | 2012 | → |
| Pathobiologic mechanisms of chronic obstructive pulmonary disease. | Tam A et al. | — | 2012 | → |
| Pathogenesis of abdominal aortic aneurysms: role of nicotine and nicotinic acetylcholine receptors. | Li ZZ et al. | — | 2012 | → |
| Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes. | Gold AB et al. | — | 2012 | → |
| PharmGKB summary: very important pharmacogene information for cytochrome P-450, family 2, subfamily A, polypeptide 6. | McDonagh EM et al. | — | 2012 | → |
| Prenatal nicotine exposure mouse model showing hyperactivity, reduced cingulate cortex volume, reduced dopamine turnover, and responsiveness to oral methylphenidate treatment. | Zhu J et al. | — | 2012 | → |
| Protein dependent fate of hepatic cells under nicotine induced stress and curcumin ameliorated condition. | Banerjee S et al. | — | 2012 | → |
| Rapid nicotine clearance is associated with greater reward and heart rate increases from intravenous nicotine. | Sofuoglu M et al. | — | 2012 | → |
| Reduced exposure evaluation of an Electrically Heated Cigarette Smoking System. Part 8: Nicotine bridging--estimating smoke constituent exposure by their relationships to both nicotine levels in mainstream cigarette smoke and in smokers. | Urban HJ et al. | — | 2012 | → |
| Relationship between amounts of daily cigarette consumption and abdominal obesity moderated by CYP2A6 genotypes in Chinese male current smokers. | Liu T et al. | — | 2012 | → |
| Relevance of mast cell-nerve interactions in intestinal nociception. | van Diest SA et al. | — | 2012 | → |
| Reproducibility of the nicotine metabolite ratio in cigarette smokers. | St Helen G et al. | — | 2012 | → |
| Research opportunities related to establishing standards for tobacco products under the Family Smoking Prevention and Tobacco Control Act. | Hecht SS | — | 2012 | → |
| Simultaneous quantification of nicotine, cotinine, trans-3'-hydroxycotinine, norcotinine and mecamylamine in human urine by liquid chromatography-tandem mass spectrometry. | Scheidweiler KB et al. | — | 2012 | → |
| Strain-dependent effects of acute, chronic, and withdrawal from chronic nicotine on fear conditioning. | Portugal GS et al. | — | 2012 | → |
| The endocrine effects of nicotine and cigarette smoke. | Tweed JO et al. | — | 2012 | → |
| [The Fetal Tobacco Syndrome - A statement of the Austrian Societies for General- and Family Medicine (ÖGAM), Gynecology and Obstetrics (ÖGGG), Hygiene, Microbiology and Preventive Medicine (ÖGHMP), Pediatrics and Adolescence Medicine (ÖGKJ) as well as Pneumology (ÖGP)]. | Horak F et al. | — | 2012 | → |
| The genetics of substance dependence. | Wang JC et al. | — | 2012 | → |
| The nicotine metabolite, cotinine, attenuates glutamate (NMDA) antagonist-related effects on the performance of the five choice serial reaction time task (5C-SRTT) in rats. | Terry AV et al. | — | 2012 | → |
| The Protective Effects of Exogenous Melatonin on Nicotine-induced Changes in Mouse Ovarian Follicles. | Mohammadghasemi F et al. | — | 2012 | → |
| Tobacco carcinogen metabolites and DNA adducts as biomarkers in head and neck cancer: potential screening tools and prognostic indicators. | Khariwala SS et al. | — | 2012 | → |
| Urinary levels of volatile organic carcinogen and toxicant biomarkers in relation to lung cancer development in smokers. | Yuan JM et al. | — | 2012 | → |
| Use of a predictive model derived from in vivo endophenotype measurements to demonstrate associations with a complex locus, CYP2A6. | Bloom AJ et al. | — | 2012 | → |
| Absorption, distribution, metabolism and excretion pharmacogenomics of drugs of abuse. | Meyer MR et al. | — | 2011 | → |
| A comprehensive evaluation of the toxicology of cigarette ingredients: inorganic compounds. | Coggins CR et al. | — | 2011 | → |
| A liquid chromatography-mass spectrometry method for nicotine and cotinine; utility in screening tobacco exposure in patients taking amiodarone. | Gabr RQ et al. | — | 2011 | → |
| A novel NADH-dependent and FAD-containing hydroxylase is crucial for nicotine degradation by Pseudomonas putida. | Tang H et al. | — | 2011 | → |
| Association of the nicotine metabolite ratio and CHRNA5/CHRNA3 polymorphisms with smoking rate among treatment-seeking smokers. | Falcone M et al. | — | 2011 | → |
| Associations of CYP2A6 genotype with smoking behaviors in southern China. | Liu T et al. | — | 2011 | → |
| Associations of nicotine intake measures with CHRN genes in Finnish smokers. | Keskitalo-Vuokko K et al. | — | 2011 | → |
| Catalytic mechanism of cytochrome P450 for 5'-hydroxylation of nicotine: fundamental reaction pathways and stereoselectivity. | Li D et al. | — | 2011 | → |
| Chemical inhibitors of cytochrome P450 isoforms in human liver microsomes: a re-evaluation of P450 isoform selectivity. | Khojasteh SC et al. | — | 2011 | → |
| Chronic nicotine consumption does not influence 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis. | Murphy SE et al. | — | 2011 | → |
| Chronic nicotine exposure exacerbates acute renal ischemic injury. | Arany I et al. | — | 2011 | → |
| Computational modeling of P450s for toxicity prediction. | Mishra NK | — | 2011 | → |
| CYP1A1/1B1 and CYP2A6/2A13 activity is conserved in cultures of differentiated primary human tracheobronchial epithelial cells. | Newland N et al. | — | 2011 | → |
| Design, baseline characteristics, and retention of African American light smokers into a randomized trial involving biological data. | Cox LS et al. | — | 2011 | → |
| Determination of the nicotine metabolites cotinine and trans-3'-hydroxycotinine in biologic fluids of smokers and non-smokers using liquid chromatography-tandem mass spectrometry: biomarkers for tobacco smoke exposure and for phenotyping cytochrome P450 2A6 activity. | Jacob P et al. | — | 2011 | → |
| Development and validation of a hydrophilic interaction chromatography-tandem mass spectrometry for quantification of nicotine and its metabolites in human maternal and cord sera. | Iwasaki Y et al. | — | 2011 | → |
| Development of an ultrasensitive immunochromatography test to detect nicotine metabolites in oral fluids. | Gonzalez JM et al. | — | 2011 | → |
| Effect of maternal nicotine exposure on neonatal rat lung development: protective effect of maternal ascorbic acid supplementation. | Maritz GS et al. | — | 2011 | → |
| Effect of mint drink on metabolism of nicotine as measured by nicotine to cotinine ratio in urine of Jordanian smoking volunteers. | Ghazi AM et al. | — | 2011 | → |
| Effects of nicotine on electroencephalography and affect in adolescent females with major depressive disorder: a pilot study. | Jaworska N et al. | — | 2011 | → |
| Electrophysiological evidence of nicotine's distracter-filtering properties in non-smokers. | Knott V et al. | — | 2011 | → |
| Genetic polymorphisms in 15q25 and 19q13 loci, cotinine levels, and risk of lung cancer in EPIC. | Timofeeva MN et al. | — | 2011 | → |
| Human θ burst stimulation enhances subsequent motor learning and increases performance variability. | Teo JT et al. | — | 2011 | → |
| Immediate consequences of cigarette smoking: rapid formation of polycyclic aromatic hydrocarbon diol epoxides. | Zhong Y et al. | — | 2011 | → |
| Interaction between heavy smoking and CYP2A6 genotypes on type 2 diabetes and its possible pathways. | Liu T et al. | — | 2011 | → |
| Investigation of the relationship between serum levels of cotinine and the renal function in active and passive smokers. | Dülger H et al. | — | 2011 | → |
| Life-long programming implications of exposure to tobacco smoking and nicotine before and soon after birth: evidence for altered lung development. | Maritz GS et al. | — | 2011 | → |
| Menthol's potential effects on nicotine dependence: a tobacco industry perspective. | Yerger VB | — | 2011 | → |
| Neural effects of acute nicotinic treatment on visual spatial attention in non-smokers. | Shah D et al. | — | 2011 | → |
| Neurophysiology of Nicotine Addiction. | Dani JA et al. | — | 2011 | → |
| N-glucuronidation of drugs and other xenobiotics by human and animal UDP-glucuronosyltransferases. | Kaivosaari S et al. | — | 2011 | → |
| Nicotine addiction causes unique detrimental effects on women's brains. | Raval AP | — | 2011 | → |
| Nicotine dependence and psychological distress: outcomes and clinical implications in smoking cessation. | Cosci F et al. | — | 2011 | → |
| Nicotine exposure and metabolizer phenotypes from analysis of urinary nicotine and its 15 metabolites by LC-MS. | Rangiah K et al. | — | 2011 | → |
| Oral fluid nicotine markers to assess smoking status and recency of use. | Scheidweiler KB et al. | — | 2011 | → |
| Plasma letrozole concentrations in postmenopausal women with breast cancer are associated with CYP2A6 genetic variants, body mass index, and age. | Desta Z et al. | — | 2011 | → |
| Prenatal IV nicotine exposure produces a sex difference in sensorimotor gating of the auditory startle reflex in adult rats. | Lacy RT et al. | — | 2011 | → |
| Probability and predictors of transition from first use to dependence on nicotine, alcohol, cannabis, and cocaine: results of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). | Lopez-Quintero C et al. | — | 2011 | → |
| Separate and combined effects of low dose ketamine and nicotine on behavioural and neural correlates of sustained attention. | Knott VJ et al. | — | 2011 | → |
| Smoking and vascular dysfunction in Africans and Caucasians from South Africa. | Zatu MC et al. | — | 2011 | → |
| Specific α4β2 nicotinic acetylcholine receptor binding of [F-18]nifene in the rhesus monkey. | Hillmer AT et al. | — | 2011 | → |
| Systematic review of the relationship between the 3-hydroxycotinine/cotinine ratio and cigarette dependence. | West O et al. | — | 2011 | → |
| The Acute Impact of Smoking One Cigarette on Cardiac Hemodynamic Parameters. | Farha KA et al. | — | 2011 | → |
| The contribution of common CYP2A6 alleles to variation in nicotine metabolism among European-Americans. | Bloom J et al. | — | 2011 | → |
| The genotoxic effect of nicotine on chromosomes of human fetal cells: the first report described as an important study. | Demirhan O et al. | — | 2011 | → |
| The moderating role of the dopamine transporter 1 gene on P50 sensory gating and its modulation by nicotine. | Millar A et al. | — | 2011 | → |
| The novel assay method for nicotine metabolism to cotinine using high performance liquid chromatography. | Miyazawa M et al. | — | 2011 | → |
| The ratio of a urinary tobacco-specific lung carcinogen metabolite to cotinine is significantly higher in passive than in active smokers. | Vogel RI et al. | — | 2011 | → |
| Tramadol requirements may need to be increased for the perioperative management of pain in smokers. | Qiu YM et al. | — | 2011 | → |
| Why do young women smoke? VI. A controlled study of nicotine effects on attention: pharmacogenetic interactions. | Rigbi A et al. | — | 2011 | → |
| Acute nicotine alteration of sensory memory impairment in smokers with schizophrenia. | Dulude L et al. | — | 2010 | → |
| Ameliorative effect of sesame lignans on nicotine toxicity in rats. | Chattopadhyay K et al. | — | 2010 | → |
| A novel pathway for nicotine degradation by Aspergillus oryzae 112822 isolated from tobacco leaves. | Meng XJ et al. | — | 2010 | → |
| Applying tobacco carcinogen and toxicant biomarkers in product regulation and cancer prevention. | Hecht SS et al. | — | 2010 | → |
| Assessment of oxidative DNA damage and repair at single cellular level via real-time monitoring of 8-OHdG biomarker. | Prabhulkar S et al. | — | 2010 | → |
| Association between nicotine metabolism and CYP2A6*1 and CYP2A6*4 genotypes in an Iranian population. | Heravi RE et al. | — | 2010 | → |
| Biomarker evaluation of Greek adolescents' exposure to secondhand smoke. | Vardavas CI et al. | — | 2010 | → |
| Biomonitoring of urinary cotinine concentrations associated with plasma levels of nicotine metabolites after daily cigarette smoking in a male Japanese population. | Nagano T et al. | — | 2010 | → |
| Carbamazepine but not valproate induces CYP2A6 activity in smokers with mental illness. | Williams JM et al. | — | 2010 | → |
| Chronic cigarette smoking: implications for neurocognition and brain neurobiology. | Durazzo TC et al. | — | 2010 | → |
| Cigarette use and cardiovascular risk in chronic kidney disease: an unappreciated modifiable lifestyle risk factor. | Stack AG et al. | — | 2010 | → |
| Determination of nicotine and nicotine metabolites in urine by hydrophilic interaction chromatography-tandem mass spectrometry: Potential use of smokeless tobacco products by ice hockey players. | Marclay F et al. | — | 2010 | → |
| Differential effects of nicotine on P50 amplitude, its gating, and their neural sources in low and high suppressors. | Knott VJ et al. | — | 2010 | → |
| Effect of an electronic nicotine delivery device (e cigarette) on desire to smoke and withdrawal, user preferences and nicotine delivery: randomised cross-over trial. | Bullen C et al. | — | 2010 | → |
| Effects of nicotine on cytochrome P450 2A6 and 2E1 activities. | Hukkanen J et al. | — | 2010 | → |
| Effects of nicotine on the amplitude and gating of the auditory P50 and its influence by dopamine D2 receptor gene polymorphism. | Knott V et al. | — | 2010 | → |
| Environmental and biological monitoring of exposures to PAHs and ETS in the general population. | Aquilina NJ et al. | — | 2010 | → |
| Environmental nicotine contamination in latent fingermarks from smoker contacts and passive smoking. | Benton M et al. | — | 2010 | → |
| Estimation of nicotine dose after low-level exposure using plasma and urine nicotine metabolites. | Benowitz NL et al. | — | 2010 | → |
| Fundamental reaction pathways for cytochrome P450-catalyzed 5'-hydroxylation and N-demethylation of nicotine. | Li D et al. | — | 2010 | → |
| Glucuronidation genotypes and nicotine metabolic phenotypes: importance of functional UGT2B10 and UGT2B17 polymorphisms. | Chen G et al. | — | 2010 | → |
| Hepatic CYP2A6 levels and nicotine metabolism: impact of genetic, physiological, environmental, and epigenetic factors. | Al Koudsi N et al. | — | 2010 | → |
| Hepatic CYP2B6 is altered by genetic, physiologic, and environmental factors but plays little role in nicotine metabolism. | Al Koudsi N et al. | — | 2010 | → |
| High-throughput simultaneous analysis of five urinary metabolites of areca nut and tobacco alkaloids by isotope-dilution liquid chromatography-tandem mass spectrometry with on-line solid-phase extraction. | Hu CW et al. | — | 2010 | → |
| Human blood concentrations of cotinine, a biomonitoring marker for tobacco smoke, extrapolated from nicotine metabolism in rats and humans and physiologically based pharmacokinetic modeling. | Yamazaki H et al. | — | 2010 | → |
| Induction of monocyte chemoattractant protein-1 by nicotine in pancreatic ductal adenocarcinoma cells: role of osteopontin. | Lazar M et al. | — | 2010 | → |
| Internet suicide guidelines: report of a life-threatening poisoning using tobacco extract. | Schneider S et al. | — | 2010 | → |
| In vivo evaluation of CYP2A6 and xanthine oxidase enzyme activities in the Serbian population. | Djordjevic N et al. | — | 2010 | → |
| Involvement of osteopontin in the matrix-degrading and proangiogenic changes mediated by nicotine in pancreatic cancer cells. | Lazar M et al. | — | 2010 | → |
| Kinetics of brain nicotine accumulation in dependent and nondependent smokers assessed with PET and cigarettes containing 11C-nicotine. | Rose JE et al. | — | 2010 | → |
| Light up and see: enhancement of the visual mismatch negativity (vMMN) by nicotine. | Fisher DJ et al. | — | 2010 | → |
| Nicotine addiction. | Benowitz NL | — | 2010 | → |
| Nicotine and its metabolites in amniotic fluid at birth--assessment of prenatal tobacco smoke exposure. | Köhler E et al. | — | 2010 | → |
| Nicotine exacerbates brain edema during in vitro and in vivo focal ischemic conditions. | Paulson JR et al. | — | 2010 | → |
| Nicotine metabolism in African Americans and European Americans: variation in glucuronidation by ethnicity and UGT2B10 haplotype. | Berg JZ et al. | — | 2010 | → |
| Repetitive nicotine exposure leads to a more malignant and metastasis-prone phenotype of SCLC: a molecular insight into the importance of quitting smoking during treatment. | Martínez-García E et al. | — | 2010 | → |
| Role of CYP2A5 in the clearance of nicotine and cotinine: insights from studies on a Cyp2a5-null mouse model. | Zhou X et al. | — | 2010 | → |
| Smoking, nicotine and neuropsychiatric disorders. | Dome P et al. | — | 2010 | → |
| Temporal stability of urinary and plasma biomarkers of tobacco smoke exposure among cigarette smokers. | Church TR et al. | — | 2010 | → |
| The effects of smoking on fracture healing. | Sloan A et al. | — | 2010 | → |
| UGT2B10 genotype influences nicotine glucuronidation, oxidation, and consumption. | Berg JZ et al. | — | 2010 | → |
| A case-control study of CYP1A1, GSTT1 and GSTM1 gene polymorphisms, pregnancy smoking and fetal growth restriction. | Delpisheh A et al. | — | 2009 | → |
| Alpha 7 subunit of nAChR regulates migration of human mesenchymal stem cells. | Schraufstatter IU et al. | — | 2009 | → |
| Analysis of myosmine, cotinine and nicotine in human toenail, plasma and saliva. | Schütte-Borkovec K et al. | — | 2009 | → |
| Are nicotine replacement therapy, varenicline or bupropion options for pregnant mothers to quit smoking? Effects on the respiratory system of the offspring. | Maritz GS | — | 2009 | → |
| Assessment of smoking behaviors and alcohol use in the national social life, health, and aging project. | Drum ML et al. | — | 2009 | → |
| Association of cotinine levels and preeclampsia among African-American women. | Janakiraman V et al. | — | 2009 | → |
| Association of serum cotinine level with a cluster of three nicotinic acetylcholine receptor genes (CHRNA3/CHRNA5/CHRNB4) on chromosome 15. | Keskitalo K et al. | — | 2009 | → |
| Characterization of a nicotine-sensitive neuronal population in rat entorhinal cortex. | Tu B et al. | — | 2009 | → |
| Conceptual DFT properties-based 3D QSAR: analysis of inhibitors of the nicotine metabolizing CYP2A6 enzyme. | Van Damme S et al. | — | 2009 | → |
| Correlation between urinary nicotine, cotinine and self-reported smoking status among educated young adults. | Man CN et al. | — | 2009 | → |
| Development of a new predictive model for interactions with human cytochrome P450 2A6 using pharmacophore ensemble/support vector machine (PhE/SVM) approach. | Leong MK et al. | — | 2009 | → |
| Differential contribution of genetic variation in multiple brain nicotinic cholinergic receptors to nicotine dependence: recent progress and emerging open questions. | Greenbaum L et al. | — | 2009 | → |
| Differential sensitivity of male germ cells to mainstream and sidestream tobacco smoke in the mouse. | Polyzos A et al. | — | 2009 | → |
| Ecology and neurobiology of toxin avoidance and the paradox of drug reward. | Hagen EH et al. | — | 2009 | → |
| Effects of acute nicotine on event-related potential and performance indices of auditory distraction in nonsmokers. | Knott VJ et al. | — | 2009 | → |
| Effects of environmental tobacco smoke in vivo on rhesus monkey semen quality, sperm function, and sperm metabolism. | Hung PH et al. | — | 2009 | → |
| Effects of nicotine exposure on in vitro metabolism of chlorpyrifos in male Sprague-Dawley rats. | Lee S et al. | — | 2009 | → |
| Evidence for endogenous formation of N'-nitrosonornicotine in some long-term nicotine patch users. | Stepanov I et al. | — | 2009 | → |
| Genetic and environmental influences on the ratio of 3'hydroxycotinine to cotinine in plasma and urine. | Swan GE et al. | — | 2009 | → |
| Genetic influences on individual differences in nicotine glucuronidation. | Lessov-Schlaggar CN et al. | — | 2009 | → |
| Genome-wide linkage of cotinine pharmacokinetics suggests candidate regions on chromosomes 9 and 11. | He Y et al. | — | 2009 | → |
| Increases in tobacco exposure biomarkers measured in non-smokers exposed to sidestream cigarette smoke under controlled conditions. | Bernert JT et al. | — | 2009 | → |
| Induction of osteopontin expression by nicotine and cigarette smoke in the pancreas and pancreatic ductal adenocarcinoma cells. | Chipitsyna G et al. | — | 2009 | → |
| Methadone-nicotine interactions in methadone maintenance treatment patients. | Elkader AK et al. | — | 2009 | → |
| Moderate use of alcohol, tobacco and cannabis during pregnancy: new approaches and update on research findings. | Huizink AC | — | 2009 | → |
| Molecular and cellular mechanisms of action of nicotine in the CNS. | Barik J et al. | — | 2009 | → |
| Nicotine chemistry, metabolism, kinetics and biomarkers. | Benowitz NL et al. | — | 2009 | → |
| Nicotine exposure can be detected in cerebrospinal fluid of active and passive smokers. | Malkawi AH et al. | — | 2009 | → |
| Nicotinic plant poisoning. | Schep LJ et al. | — | 2009 | → |
| Passive immunization with a nicotine-specific monoclonal antibody decreases brain nicotine levels but does not precipitate withdrawal in nicotine-dependent rats. | Roiko SA et al. | — | 2009 | → |
| Pharmacology of nicotine: addiction, smoking-induced disease, and therapeutics. | Benowitz NL | — | 2009 | → |
| Prediction of birth weight by cotinine levels during pregnancy in a population of black smokers. | El-Mohandes AA et al. | — | 2009 | → |
| Prenatal exposure of rats to nicotine causes persistent alterations of nicotinic cholinergic receptors. | Gold AB et al. | — | 2009 | → |
| Presence of the carcinogen N'-nitrosonornicotine in the urine of some users of oral nicotine replacement therapy products. | Stepanov I et al. | — | 2009 | → |
| Purification of drugs from biological fluids by counter-current chromatography. | Hochlowski JE et al. | — | 2009 | → |
| QSAR of cytochrome inhibitors. | Roy K et al. | — | 2009 | → |
| Racial differences in serum cotinine levels of smokers. | Signorello LB et al. | — | 2009 | → |
| SLC6A3 and body mass index in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. | Azzato EM et al. | — | 2009 | → |
| The facilitatory effects of intermittent theta burst stimulation on corticospinal excitability are enhanced by nicotine. | Swayne OB et al. | — | 2009 | → |
| Tobacco addiction and pharmacogenetics of nicotine metabolism. | Swan GE et al. | — | 2009 | → |
| Toward an "omic" physiopathology of reactive chemicals: thirty years of mass spectrometric study of the protein adducts with endogenous and xenobiotic compounds. | Rubino FM et al. | — | 2009 | → |
| Urine nicotine metabolite concentrations in relation to plasma cotinine during low-level nicotine exposure. | Benowitz NL et al. | — | 2009 | → |
| Utility and relationships of biomarkers of smoking in African-American light smokers. | Ho MK et al. | — | 2009 | → |
| CYP2A6 polymorphisms and risk for tobacco-related cancers. | Rossini A et al. | — | 2008 | → |
| Effects of smoking on the pharmacokinetics and pharmacodynamics of a nicotine patch. | Yun HY et al. | — | 2008 | → |
| IgE-induced degranulation of mucosal mast cells is negatively regulated via nicotinic acetylcholine receptors. | Kageyama-Yahara N et al. | — | 2008 | → |
| Nicotine intake in cigarette smokers in England: distribution and demographic correlates. | Fidler JA et al. | — | 2008 | → |
| Nicotine metabolism in three ethnic/racial groups with different risks of lung cancer. | Derby KS et al. | — | 2008 | → |
| Nicotinic Receptors: Role in Addiction and Other Disorders of the Brain. | Sharma G et al. | — | 2008 | → |
| Pharmacotherapy for smoking cessation. | Carrozzi L et al. | — | 2008 | → |
| Prenatal smoking exposure and asymmetric fetal growth restriction. | Delpisheh A et al. | — | 2008 | → |