Alcohol effects on movement-related potentials: a measure of impulsivity?
- Authors
- Marinkovic, K; Halgren, E; Klopp, J; Maltzman, I
- Year
- 2000
- Journal
- Journal of studies on alcohol
- PMID
- 10627093
- DOI
- 10.15288/jsa.2000.61.24
OBJECTIVE: To assess the effects of acute alcohol intoxication on lateralized readiness potential (LRP), a central measure of movement-related brain activity, and the potential association of such effects with personality measures. METHOD: Male volunteers (N = 12) alternated responding hands during a "go/no go" verbal recognition task across all four sessions of the balanced placebo design in which beverage content (either juice only or a vodka and juice mixture that raised the average blood alcohol concentration to 0.045%) was crossed with instructions as to beverage content. RESULTS: Whereas the instructions had no effect on behavioral (response accuracy and reaction time) and physiological (LRP) measures, alcohol decreased reaction times adjusted for psychometer speed. As expected, large LRPs were recorded on "go" trials and were not affected by the beverage. However, the "no go" words that did not require and did not evoke motor responses, also evoked significant LRPs under alcohol but not placebo. Since only trials with correct responses and correct abstentions from responses were included in the averages, the motor preparation was not completed and was terminated before the motor response on "no go" trials. Similarly, there was a decrease in spectral power of the movement-related mu-rhythm on "no go" trials under alcohol. CONCLUSIONS: Alcohol may result in disinhibition such that the "response execution" process is activated based on very preliminary stimulus evaluation. This alcohol-induced brain activity signaling premature motor preparation exhibited correlation trends with personality traits related to impulsivity, hyperactivity and antisocial tendencies, thus concurring with other evidence that indicates commonalities between alcoholism and impulsivity, disinhibition and antisocial behaviors. The LRP on "no go" trials could potentially be used as a psychological index of the impulsiveness induced by alcohol intoxication.
No figures extracted from this document.
No chunks β full text not yet ingested.
No entities extracted from this document yet.
No uploaded files.
No citations found.
In this knowledge base
| Title | Year | PMID |
|---|---|---|
| Understanding alcohol use disorders with neuroelectrophysiology. | 2014 | 25307587 |
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Neurobiology of Aggression-Review of Recent Findings and Relationship with Alcohol and Trauma. | Fritz M et al. | β | 2023 | β |
| Theta oscillatory dynamics of inhibitory control, error processing, and post-error adjustments: Neural underpinnings and alcohol-induced dysregulation in social drinkers. | Marinkovic K et al. | β | 2022 | β |
| Decision- and feedback-related brain potentials reveal risk processing mechanisms in patients with alcohol use disorder. | Sehrig S et al. | β | 2019 | β |
| Neural oscillatory dynamics of inhibitory control in young adult binge drinkers. | Holcomb LA et al. | β | 2019 | β |
| On the Neurobiological Role of Oxidative Stress in Alcohol-Induced Impulsive, Aggressive and Suicidal Behavior. | Tobore TO | β | 2019 | β |
| Jacobian Maps Reveal Under-reported Brain Regions Sensitive to Extreme Binge Ethanol Intoxication in the Rat. | Zhao Q et al. | β | 2018 | β |
| When the brain changes its mind: Oscillatory dynamics of conflict processing and response switching in a flanker task during alcohol challenge. | Beaton LE et al. | β | 2018 | β |
| Neurodynamic correlates of response inhibition from emerging to mid adulthood. | KneΕΎeviΔ M et al. | β | 2017 | β |
| The sensitivity of laboratory tests assessing driving related skills to dose-related impairment of alcohol: A literature review. | Jongen S et al. | β | 2016 | β |
| Alcohol disinhibition of behaviors in C. elegans. | Topper SM et al. | β | 2014 | β |
| Spatio-temporal processing of words and nonwords: hemispheric laterality and acute alcohol intoxication. | Marinkovic K et al. | β | 2014 | β |
| Understanding alcohol use disorders with neuroelectrophysiology. | Rangaswamy M et al. | β | 2014 | β |
| Acute alcohol consumption impairs controlled but not automatic processes in a psychophysical pointing paradigm. | Johnston K et al. | β | 2013 | β |
| Effects of acute alcohol intoxication on saccadic conflict and error processing. | Marinkovic K et al. | β | 2013 | β |
| Acute alcohol intoxication impairs top-down regulation of Stroop incongruity as revealed by blood oxygen level-dependent functional magnetic resonance imaging. | Marinkovic K et al. | β | 2012 | β |
| Effects of Alcohol Intoxication on Response Conflict in a Flanker Task. | Marinkovic K et al. | β | 2012 | β |
| Event-Related Theta Power during Lexical-Semantic Retrieval and Decision Conflict is Modulated by Alcohol Intoxication: Anatomically Constrained MEG. | Marinkovic K et al. | β | 2012 | β |
| Effects of alcohol on inhibitory processes. | Rose AK et al. | β | 2008 | β |
| Alcohol: effects on neurobehavioral functions and the brain. | Oscar-Berman M et al. | β | 2007 | β |
| Attentional blink in adolescents with varying levels of impulsivity. | Ray Li CS et al. | β | 2005 | β |
| Alcohol consumption impairs detection of performance errors in mediofrontal cortex. | Ridderinkhof KR et al. | β | 2002 | β |
| Arousal-related P3a to novel auditory stimuli is abolished by a moderately low alcohol dose. | Marinkovic K et al. | β | 2001 | β |
| Prolonged neurophysiological effects of cumulative wine drinking. | Ilan AB et al. | β | 2001 | β |
| Psychiatric aspects of impulsivity. | Moeller FG et al. | β | 2001 | β |