Anticraving medications for relapse prevention: a possible new class of psychoactive medications.
paper
Cited
Public
Unavailable
- Authors
- O'Brien, Charles P
- Year
- 2005
- Journal
- The American journal of psychiatry
- PMID
- 16055763
- DOI
- 10.1176/appi.ajp.162.8.1423
Psychiatrists have gradually developed a list of medications that are effective in the treatment of addictive disorders. Although alcoholism has received the most attention, nicotine, heroin, and cocaine have all been shown to be influenced by heredity. Of course, the immediate goal is the reduction of drug craving and the prevention of relapse to compulsive drug taking. A medication that can aid in the maintenance of the opiate-free state is naltrexone, a specific opiate antagonist. Naltrexone is also a good example of an anticraving medication used in the treatment of alcoholism. Clinicians currently have two types of medication to aid in the treatment of tobacco use disorder, arguably the most important addiction. Bupropion and nicotine replacement can be given in a coordinated fashion to provide the best available results. At present, no medication is approved by the Food and Drug Administration for the indication of cocaine addiction. Recently, however, five different medications, already approved for other purposes, have been found to be effective among cocaine addicts. Despite clinical trials that show benefit, anticraving medications are not well known and are underused by clinicians. Addiction is a heterogeneous condition, with variability in reactivity to the drug of abuse and to the medications available to treat it. Recent developments in pharmacogenetics may result in improved selection of medications based on genotype.
No figures extracted from this document.
No chunks β full text not yet ingested.
No entities extracted from this document yet.
No uploaded files.
Not in any collection.
No citations found.
In this knowledge base
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Assessing Cravings Among Individuals with Alcohol Dependence Syndrome Prescribed with Anti-craving Medication: A Prospective Observational Study. | Sultana M et al. | β | 2025 | β |
| Behavior classification: Introducing machine learning approaches for classification of sign-tracking, goal-tracking and beyond. | Godin C et al. | β | 2025 | β |
| Predictors of substance use during treatment for addiction: A network analysis of ecological momentary assessment data. | Serre F et al. | β | 2025 | β |
| Spontaneous oxycodone withdrawal disrupts sleep, diurnal, and electrophysiological dynamics in rats. | Gulledge M et al. | β | 2025 | β |
| Use of semaglutide in a 54-year-old patient with cocaine abuse and weight loss: a case report. | Romeo VM | β | 2025 | β |
| A historical perspective on clonidine as an alpha-2A receptor agonist in the treatment of addictive behaviors: Focus on opioid dependence. | Gold MS et al. | β | 2024 | β |
| Conditional deletion of the AMPA-GluA1 and NMDA-GluN1 receptor subunit genes in midbrain D1 neurons does not alter cocaine reward in mice. | Borruto AM et al. | β | 2024 | β |
| Craving changes in first 14 days of addiction treatment: an outcome predictor of 5 years substance use status? | Baillet E et al. | β | 2024 | β |
| Impact of MAOA Gene Polymorphism on the Efficacy of Antidepressant Treatment and Craving Severity for Betel Quid Use Disorder. | Hung CC et al. | β | 2024 | β |
| Tackling addictive behaviors through memory suppression: A scoping review and perspective. | de Almeida-Antunes NA et al. | β | 2024 | β |
| Cannabis craving in response to alcohol cues among adolescents and young adults in the laboratory and in daily life. | Wycoff AM et al. | β | 2023 | β |
| Cocaine-Induced Time-Dependent Alterations in Cytochrome P450 and Liver Function. | JastrzΔbska J et al. | β | 2023 | β |
| Morphine-withdrawal aversive memories and their extinction modulate H4K5 acetylation and Brd4 activation in the rat hippocampus and basolateral amygdala. | Franco-GarcΓa A et al. | β | 2023 | β |
| Network analysis of internet addiction and sleep disturbance symptoms. | Lu JX et al. | β | 2023 | β |
| NMDA Receptors in the Rat Paraventricular Thalamic Nucleus Reduce the Naloxone-induced Morphine Withdrawal. | Babaei F et al. | β | 2023 | β |
| PET imaging of dopamine transporters and D2/D3 receptors in female monkeys: effects of chronic cocaine self-administration. | Allen MI et al. | β | 2023 | β |
| Shared Mechanisms of GABAergic and Opioidergic Transmission Regulate Corticolimbic Reward Systems and Cognitive Aspects of Motivational Behaviors. | Hosseinzadeh Sahafi O et al. | β | 2023 | β |
| The Craving-Manager smartphone app designed to diagnose substance use/addictive disorders, and manage craving and individual predictors of relapse: a study protocol for a multicenter randomized controlled trial. | Serre F et al. | β | 2023 | β |
| VR for Studying the Neuroscience of Emotional Responses. | Andreatta M et al. | β | 2023 | β |
| VU0155041, a positive allosteric modulator of mGluR4, in the nucleus accumbens facilitates extinction and inhibits the reinstatement of morphine-induced conditioned place preference in male rats. | Ebrahimi Z et al. | β | 2023 | β |
| Momentary associations between stress and alcohol craving in the naturalistic environment: differential associations for Black and White young adults. | Pedersen SL et al. | β | 2022 | β |
| Ranking the contribution of behavioral measures comprising oxycodone self-administration to reinstatement of drug-seeking in male and female rats. | Guha SK et al. | β | 2022 | β |
| Utility of 'substance use disorder' as a heuristic for understanding overeating and obesity. | O'Connor RM et al. | β | 2022 | β |
| Andrographis paniculata and Its Main Bioactive Ingredient Andrographolide Decrease Alcohol Drinking and Seeking in Rats Through Activation of Nuclear PPARΞ³ Pathway. | Stopponi S et al. | β | 2021 | β |
| CaMKII Modulates Diacylglycerol Lipase-Ξ± Activity in the Rat Nucleus Accumbens after Incubation of Cocaine Craving. | Murray CH et al. | β | 2021 | β |
| Effective connectivity predicts cognitive empathy in cocaine addiction: a spectral dynamic causal modeling study. | Wei L et al. | β | 2021 | β |
| Facilitating mGluR4 activity reverses the long-term deleterious consequences of chronic morphine exposure in male mice. | Becker JAJ et al. | β | 2021 | β |
| Inactivation of the infralimbic cortex decreases discriminative stimulus-controlled relapse to cocaine seeking in rats. | Madangopal R et al. | β | 2021 | β |
| Influence of dopamine-related genes on craving, impulsivity, and aggressiveness in Korean males with alcohol use disorder. | Park CI et al. | β | 2021 | β |
| Psychometric properties and longitudinal measurement invariance of the drug craving scale: Modification of the Polish version of the Penn Alcohol Craving Scale (PACS). | Opozda-Suder S et al. | β | 2021 | β |
| Sign- and goal-tracking score does not correlate with addiction-like behavior following prolonged cocaine self-administration. | PohoΕalΓ‘ V et al. | β | 2021 | β |
| Systematic Review and Meta-Analysis: Treatment of Substance Use Disorder in Attention Deficit Hyperactivity Disorder. | Fluyau D et al. | β | 2021 | β |
| The Adenosine A2A Receptor Activation in Nucleus Accumbens Suppress Cue-Induced Reinstatement of Propofol Self-administration in Rats. | Dong Z et al. | β | 2021 | β |
| The self-serving benefits of being a good host: A role for our micro-inhabitants in shaping opioids' function. | Eitan S et al. | β | 2021 | β |
| Transdiagnostic connectome-based prediction of craving | Garrison KA et al. | β | 2021 | β |
| Blockade of D3 receptor prevents changes in DAT and D3R expression in the mesolimbic dopaminergic circuit produced by social stress- and cocaine prime-induced reinstatement of cocaine-CPP. | Guerrero-Bautista R et al. | β | 2020 | β |
| Hab-o Shefa, a Persian Medicine Compound for Maintenance Treatment of Opioid Dependence: Randomized Placebo-Controlled Clinical Trial. | Moosavyzadeh A et al. | β | 2020 | β |
| Is craving a risk factor for substance use among treatment-seeking individuals with alcohol and other drugs use disorders? A meta-analytic review. | Cavicchioli M et al. | β | 2020 | β |
| Pre-exposure of adolescent mice to morphine results in stronger sensitization and reinstatement of conditioned place preference than pre-exposure to hydrocodone. | Madison CA et al. | β | 2020 | β |
| Preliminary examination of the orexin system on relapse-related factors in cocaine use disorder. | Suchting R et al. | β | 2020 | β |
| Spermidine, a positive modulator of the NMDA receptor, facilitates extinction and prevents the reinstatement of morphine-induced conditioned place preference in mice. | Girardi BA et al. | β | 2020 | β |
| The potent psychomotor, rewarding and reinforcing properties of 3-fluoromethamphetamine in rodents. | Ryu IS et al. | β | 2020 | β |
| Craving and opioid use disorder: A scoping review. | Kleykamp BA et al. | β | 2019 | β |
| Discriminative stimuli are sufficient for incubation of cocaine craving. | Madangopal R et al. | β | 2019 | β |
| Effect of social housing and oxytocin on the motivation to self-administer methamphetamine in female rats. | Westenbroek C et al. | β | 2019 | β |
| Moderate-Intensity Aerobic Exercise Restores Appetite and Prefrontal Brain Activity to Images of Food Among Persons Dependent on Methamphetamine: A Functional Near-Infrared Spectroscopy Study. | Wang H et al. | β | 2019 | β |
| Opioid Substitution Therapy: Achieving Harm Reduction While Searching for a Prophylactic Solution. | Blum K et al. | β | 2019 | β |
| Quantitative evaluation of cue-induced reinstatement model for evidence-based experimental optimization. | Oberhofer J et al. | β | 2019 | β |
| The monoamine stabilizer (-)-OSU6162 prevents the alcohol deprivation effect and improves motor impulsive behavior in rats. | Fredriksson I et al. | β | 2019 | β |
| Anticraving therapy for alcohol use disorder: A clinical review. | Shen WW | β | 2018 | β |
| Approach bias modification for cannabis use disorder: A proof-of-principle study. | Sherman BJ et al. | β | 2018 | β |
| Cannabidiol inhibits priming-induced reinstatement of methamphetamine in REM sleep deprived rats. | Karimi-Haghighi S et al. | β | 2018 | β |
| Comparison of the Role of D1- and D2-Like Receptors in the CA1 Region of the Hippocampus in the Reinstatement Induced by a Subthreshold Dose of Morphine and Forced Swim Stress in Extinguished Morphine-CPP in Rats. | Nazari-Serenjeh F et al. | β | 2018 | β |
| Current Evidence on Heart Rate Variability Biofeedback as a Complementary Anticraving Intervention. | Alayan N et al. | β | 2018 | β |
| Melatonin in drug addiction and addiction management: Exploring an evolving multidimensional relationship. | Onaolapo OJ et al. | β | 2018 | β |
| Reversing Cocaine-Induced Adaptations and Reducing Relapse: An Opportunity for Repurposing Riluzole. | Ziminski JJ et al. | β | 2018 | β |
| Circuit and Synaptic Plasticity Mechanisms of Drug Relapse. | Dong Y et al. | β | 2017 | β |
| Commentary on Schmitz et al. (2017): Advancing medication development for addiction-behavioral and neuroimaging outcomes as indirect biomarkers of target engagement. | Farokhnia M et al. | β | 2017 | β |
| Craving Behavior Intervention in Ameliorating College Students' Internet Game Disorder: A Longitudinal Study. | Deng LY et al. | β | 2017 | β |
| Differential behavioral and molecular alterations upon protracted abstinence from cocaine versus morphine, nicotine, THC and alcohol. | Becker JAJ et al. | β | 2017 | β |
| Effects of nicotine versus placebo e-cigarette use on symptom relief during initial tobacco abstinence. | Perkins KA et al. | β | 2017 | β |
| Epigenetics: a link between addiction and social environment. | Ajonijebu DC et al. | β | 2017 | β |
| Involvement of AMPA/Kainate Glutamate Receptor in the Extinction and Reinstatement of Morphine-Induced Conditioned Place Preference: A Behavioral and Molecular Study. | Siahposht-Khachaki A et al. | β | 2017 | β |
| Management of precipitated opiate withdrawal syndrome induced by nalmefene mistakenly prescribed in opiate-dependent patients: a review for clinicians. | Franchitto N et al. | β | 2017 | β |
| PPAR-gamma agonist pioglitazone modifies craving intensity and brain white matter integrity in patients with primary cocaine use disorder: a double-blind randomized controlled pilot trial. | Schmitz JM et al. | β | 2017 | β |
| Animal models of drug relapse and craving: From drug priming-induced reinstatement to incubation of craving after voluntary abstinence. | Venniro M et al. | β | 2016 | β |
| Attenuation of cue-induced reinstatement of nicotine seeking by URB597 through cannabinoid CB1 receptor in rats. | Forget B et al. | β | 2016 | β |
| Chronic methamphetamine self-administration disrupts cortical control of cognition. | Bernheim A et al. | β | 2016 | β |
| Common Brain Mechanisms of Chronic Pain and Addiction. | Elman I et al. | β | 2016 | β |
| Emerging Pharmacologic Treatments for Adolescent Substance Use: Challenges and New Directions. | Miranda R et al. | β | 2016 | β |
| Exploration of Core Symptoms for the Diagnosis of Alcohol Dependence in the ICD-10. | Yoshimura A et al. | β | 2016 | β |
| Food cue reactivity and craving predict eating and weight gain: a meta-analytic review. | Boswell RG et al. | β | 2016 | β |
| Potential benefit of lamotrigine in managing ketamine use disorder. | Huang MC et al. | β | 2016 | β |
| Statins Reduce the Risks of Relapse to Addiction in Rats. | Chauvet C et al. | β | 2016 | β |
| Stress-Induced Reinstatement of Drug Seeking: 20 Years of Progress. | Mantsch JR et al. | β | 2016 | β |
| Add-on deep transcranial magnetic stimulation (dTMS) in patients with dysthymic disorder comorbid with alcohol use disorder: a comparison with standard treatment. | Girardi P et al. | β | 2015 | β |
| Craving and substance use among patients with alcohol, tobacco, cannabis or heroin addiction: a comparison of substance- and person-specific cues. | Fatseas M et al. | β | 2015 | β |
| Differential regulation of mGlu5 R and ΞOPr by priming- and cue-induced reinstatement of cocaine-seeking behaviour in mice. | Georgiou P et al. | β | 2015 | β |
| Nosologic Comparisons of DSM-IV and DSM-5 Alcohol and Drug Use Disorders: Results From the National Epidemiologic Survey on Alcohol and Related Conditions-III. | Goldstein RB et al. | β | 2015 | β |
| Pharmacological treatments for drug misuse and dependence. | Reed K et al. | β | 2015 | β |
| Psychometric assessment of the craving to tan questionnaire. | Ashrafioun L et al. | β | 2015 | β |
| Relationship between craving and ghrelin, adiponectin, and resistin levels in patients with alcoholism. | AkkiΕi Kumsar N et al. | β | 2015 | β |
| Role of corticostriatal circuits in context-induced reinstatement of drug seeking. | Marchant NJ et al. | β | 2015 | β |
| Trajectories of Drinking Urges During Individual- and Couple-based Cognitive-Behavioral Treatment for Alcohol Use Disorders. | Hallgren KA et al. | β | 2015 | β |
| Validation of the cocaine versions of the Obsessive Compulsive Drug Use Scale and the Desires for Drug Questionnaire. | Lievaart M et al. | β | 2015 | β |
| Adolescent brain maturation and smoking: what we know and where we're headed. | Lydon DM et al. | β | 2014 | β |
| Alcohol craving in adolescents: bridging the laboratory and natural environment. | Ramirez J et al. | β | 2014 | β |
| Altered social and non-social decision-making in recreational and dependent cocaine users. | Hulka LM et al. | β | 2014 | β |
| Amylin receptor signaling in the nucleus accumbens negatively modulates ΞΌ-opioid-driven feeding. | Baisley SK et al. | β | 2014 | β |
| A pilot study of brief heart rate variability biofeedback to reduce craving in young adult men receiving inpatient treatment for substance use disorders. | Eddie D et al. | β | 2014 | β |
| Contributions of the paraventricular thalamic nucleus in the regulation of stress, motivation, and mood. | Hsu DT et al. | β | 2014 | β |
| Drug abstinence: exploring animal models and behavioral treatment strategies. | Peck JA et al. | β | 2014 | β |
| Have the genetics of cannabis involvement gone to pot? | Agrawal A et al. | β | 2014 | β |
| Impaired emotional empathy and related social network deficits in cocaine users. | Preller KH et al. | β | 2014 | β |
| Is the alcohol deprivation effect genetically mediated? Studies with HXB/BXH recombinant inbred rat strains. | Vanderlinden LA et al. | β | 2014 | β |
| Pharmacological evidence for an abstinence-induced switch in 5-HT1B receptor modulation of cocaine self-administration and cocaine-seeking behavior. | Pentkowski NS et al. | β | 2014 | β |
| Pharmacological means of reducing human drug dependence: a selective and narrative review of the clinical literature. | Lin SK | β | 2014 | β |
| Prolonged withdrawal following cocaine self-administration increases resistance to punishment in a cocaine binge. | Gancarz-Kausch AM et al. | β | 2014 | β |
| The association between negative affect and prescription opioid misuse in patients with chronic pain: the mediating role of opioid craving. | Martel MO et al. | β | 2014 | β |
| The role of guanfacine as a therapeutic agent to address stress-related pathophysiology in cocaine-dependent individuals. | Fox H et al. | β | 2014 | β |
| Drug Craving Terminology among Opiate Dependents; A Mixed Method Study. | Maarefvand M et al. | β | 2013 | β |
| DSM-5 criteria for substance use disorders: recommendations and rationale. | Hasin DS et al. | β | 2013 | β |
| Efficacy of add-on deep transcranial magnetic stimulation in comorbid alcohol dependence and dysthymic disorder: three case reports. | Rapinesi C et al. | β | 2013 | β |
| Ethical implications of research on craving. | Carter A et al. | β | 2013 | β |
| Genetic differences in the modulation of accumbal glutamate and Ξ³-amino butyric acid levels after cocaine-induced reinstatement. | MiguΓ©ns M et al. | β | 2013 | β |
| Genetic influences on craving for alcohol. | Agrawal A et al. | β | 2013 | β |
| Medications for substance use disorders. | Douaihy AB et al. | β | 2013 | β |
| Modeling relapse situations in the human laboratory. | Sinha R | β | 2013 | β |
| Mu-opioid stimulation in rat prefrontal cortex engages hypothalamic orexin/hypocretin-containing neurons, and reveals dissociable roles of nucleus accumbens and hypothalamus in cortically driven feeding. | Mena JD et al. | β | 2013 | β |
| Opioidergic and dopaminergic manipulation of gambling tendencies: a preliminary study in male recreational gamblers. | Porchet RI et al. | β | 2013 | β |
| Prevalence of DSM-IV and DSM-5 alcohol, cocaine, opioid, and cannabis use disorders in a largely substance dependent sample. | Peer K et al. | β | 2013 | β |
| Recent developments in animal models of drug relapse. | Marchant NJ et al. | β | 2013 | β |
| Relaxin-3/RXFP3 system regulates alcohol-seeking. | Ryan PJ et al. | β | 2013 | β |
| Roles of dopaminergic innervation of nucleus accumbens shell and dorsolateral caudate-putamen in cue-induced morphine seeking after prolonged abstinence and the underlying D1- and D2-like receptor mechanisms in rats. | Gao J et al. | β | 2013 | β |
| Temptation to drink as a predictor of drinking outcomes following psychosocial treatment for alcohol dependence. | Witkiewitz K | β | 2013 | β |
| The reinstatement model of drug relapse: recent neurobiological findings, emerging research topics, and translational research. | Bossert JM et al. | β | 2013 | β |
| Analyses related to the development of DSM-5 criteria for substance use related disorders: 2. Proposed DSM-5 criteria for alcohol, cannabis, cocaine and heroin disorders in 663 substance abuse patients. | Hasin DS et al. | β | 2012 | β |
| An emerging role for the Mammalian target of rapamycin in "pathological" protein translation: relevance to cocaine addiction. | Dayas CV et al. | β | 2012 | β |
| Beyond drug use: a systematic consideration of other outcomes in evaluations of treatments for substance use disorders. | Tiffany ST et al. | β | 2012 | β |
| Cocaine use in the past year is associated with altitude of residence. | Fiedler KK et al. | β | 2012 | β |
| Current pharmacotherapy options for bulimia nervosa and binge eating disorder. | McElroy SL et al. | β | 2012 | β |
| Effects of environmental enrichment on the incubation of cocaine craving. | Chauvet C et al. | β | 2012 | β |
| Effects of prenatal immune activation and peri-adolescent stress on amphetamine-induced conditioned place preference in the rat. | Richtand NM et al. | β | 2012 | β |
| Efficacy of disulfiram and Twelve Step Facilitation in cocaine-dependent individuals maintained on methadone: a randomized placebo-controlled trial. | Carroll KM et al. | β | 2012 | β |
| How does stress lead to risk of alcohol relapse? | Sinha R | β | 2012 | β |
| Improving abstinence in comorbid substance disorder in a mental health unit. | Solar A | β | 2012 | β |
| K(Ca)2 channels: novel therapeutic targets for treating alcohol withdrawal and escalation of alcohol consumption. | Mulholland PJ | β | 2012 | β |
| Neural correlates of stress-induced and cue-induced drug craving: influences of sex and cocaine dependence. | Potenza MN et al. | β | 2012 | β |
| Orexin-1 receptor mediation of cocaine seeking in male and female rats. | Zhou L et al. | β | 2012 | β |
| Pathological Gambling: Neuropsychopharmacology and Treatment. | Bullock SA et al. | β | 2012 | β |
| Repeated episodes of heroin cause enduring alterations of circadian activity in protracted abstinence. | Stinus L et al. | β | 2012 | β |
| Social dominance in female monkeys: dopamine receptor function and cocaine reinforcement. | Nader MA et al. | β | 2012 | β |
| Substance abuse disorders. | Reid AG et al. | β | 2012 | β |
| The clinical significance of drug craving. | Tiffany ST et al. | β | 2012 | β |
| The effects of calorie restriction on operant-responding for alcohol in the alcohol preferring (iP) rat. | Guccione L et al. | β | 2012 | β |
| Acamprosate in the treatment of binge eating disorder: a placebo-controlled trial. | McElroy SL et al. | β | 2011 | β |
| Addiction and brain reward and antireward pathways. | Gardner EL | β | 2011 | β |
| A food predictive cue must be attributed with incentive salience for it to induce c-fos mRNA expression in cortico-striatal-thalamic brain regions. | Flagel SB et al. | β | 2011 | β |
| Alcohol craving and the dimensionality of alcohol disorders. | Keyes KM et al. | β | 2011 | β |
| Can the chronic administration of the combination of buprenorphine and naloxone block dopaminergic activity causing anti-reward and relapse potential? | Blum K et al. | β | 2011 | β |
| Chronic alcohol neuroadaptation and stress contribute to susceptibility for alcohol craving and relapse. | Breese GR et al. | β | 2011 | β |
| Clonidine blocks stress-induced craving in cocaine users. | Jobes ML et al. | β | 2011 | β |
| Cocaine Addiction Treatments to improve Control and reduce Harm (CATCH): new pharmacological treatment options for crack-cocaine dependence in the Netherlands. | Nuijten M et al. | β | 2011 | β |
| Differential effect of opioid and cannabinoid receptor blockade on heroin-seeking reinstatement and cannabinoid substitution in heroin-abstinent rats. | Fattore L et al. | β | 2011 | β |
| [Disulfiram and addiction: reminders and new perspectives of use]. | Charpeaud T et al. | β | 2011 | β |
| Drugs and addiction: an introduction to epigenetics. | Wong CC et al. | β | 2011 | β |
| Effects of daily treatment with citicoline: a double-blind, placebo-controlled study in cocaine-dependent volunteers. | Licata SC et al. | β | 2011 | β |
| Hippocampus, amygdala, and stress: interacting systems that affect susceptibility to addiction. | Belujon P et al. | β | 2011 | β |
| HIV, alcohol dependence, and the criminal justice system: a review and call for evidence-based treatment for released prisoners. | Springer SA et al. | β | 2011 | β |
| Inhibition of morphine-induced cAMP overshoot: a cell-based assay model in a high-throughput format. | Xia M et al. | β | 2011 | β |
| Naltrexone attenuates amphetamine-induced locomotor sensitization in the rat. | HΓ€ggkvist J et al. | β | 2011 | β |
| Natural rewards, neuroplasticity, and non-drug addictions. | Olsen CM | β | 2011 | β |
| Oral administration of levo-tetrahydropalmatine attenuates reinstatement of extinguished cocaine seeking by cocaine, stress or drug-associated cues in rats. | Figueroa-Guzman Y et al. | β | 2011 | β |
| Prevention of alcohol dependence: strategies for selective, indicated, and universal prevention. | Manjunatha N et al. | β | 2011 | β |
| Safety, tolerability, and feasibility of high-dose naltrexone in alcohol dependence: an open-label study. | Yoon G et al. | β | 2011 | β |
| Selective norepinephrine reuptake inhibition by atomoxetine prevents cue-induced heroin and cocaine seeking. | Economidou D et al. | β | 2011 | β |
| Sodium oxybate in the treatment of binge eating disorder: an open-label, prospective study. | McElroy SL et al. | β | 2011 | β |
| Acute effects of sublingual buprenorphine on brain responses to heroin-related cues in early-abstinent heroin addicts: an uncontrolled trial. | Mei W et al. | β | 2010 | β |
| Aerobic exercise attenuates reinstatement of cocaine-seeking behavior and associated neuroadaptations in the prefrontal cortex. | Lynch WJ et al. | β | 2010 | β |
| Brain imaging studies in pathological gambling. | van Holst RJ et al. | β | 2010 | β |
| Determinants of cue-elicited craving and physiologic reactivity in methamphetamine-dependent subjects in the laboratory. | Tolliver BK et al. | β | 2010 | β |
| Early adoption of injectable naltrexone for alcohol-use disorders: findings in the private-treatment sector. | Abraham AJ et al. | β | 2010 | β |
| Environmental living conditions introduced during forced abstinence alter cocaine-seeking behavior and Fos protein expression. | Thiel KJ et al. | β | 2010 | β |
| Fos after single and repeated self-administration of cocaine and saline in the rat: emphasis on the Basal forebrain and recalibration of expression. | Zahm DS et al. | β | 2010 | β |
| Orphanin FQ/nociceptin not only blocks but also reverses behavioral adaptive changes induced by repeated cocaine in mice. | Bebawy D et al. | β | 2010 | β |
| Outcome of long-term heroin-assisted treatment offered to chronic, treatment-resistant heroin addicts in the Netherlands. | Blanken P et al. | β | 2010 | β |
| Performance of a craving criterion in DSM alcohol use disorders. | Cherpitel CJ et al. | β | 2010 | β |
| Post-soviet placebos: epistemology and authority in Russian treatments for alcoholism. | Raikhel E | β | 2010 | β |
| Prolonged duration of craving, mood, and autonomic responses elicited by cues and imagery in smokers: Effects of tobacco deprivation and sex. | Heishman SJ et al. | β | 2010 | β |
| Stimulation of dopamine D2/D3 but not D1 receptors in the central amygdala decreases cocaine-seeking behavior. | Thiel KJ et al. | β | 2010 | β |
| Stimulation of medial prefrontal cortex serotonin 2C (5-HT(2C)) receptors attenuates cocaine-seeking behavior. | Pentkowski NS et al. | β | 2010 | β |
| The efficacy of smoking cessation therapies in cardiac patients: a meta-analysis of randomized controlled trials. | Eisenberg MJ et al. | β | 2010 | β |
| Two scales to evaluate cocaine craving. | MuΓ±oz MA et al. | β | 2010 | β |
| Abuse liability assessment of tobacco products including potential reduced exposure products. | Carter LP et al. | β | 2009 | β |
| Alcohol and opioid dependence medications: prescription trends, overall and by physician specialty. | Mark TL et al. | β | 2009 | β |
| Caffeine use in children: what we know, what we have left to learn, and why we should worry. | Temple JL | β | 2009 | β |
| Clinical and laboratory assessment of the subjective experience of drug craving. | Rosenberg H | β | 2009 | β |
| Cocaine-induced reinstatement during limited and extended drug access conditions in rhesus monkeys. | Henry PK et al. | β | 2009 | β |
| Compulsive overeating as an addiction disorder. A review of theory and evidence. | Davis C et al. | β | 2009 | β |
| Effects of chronic administration of drugs of abuse on impulsive choice (delay discounting) in animal models. | Setlow B et al. | β | 2009 | β |
| Identifying the neural circuitry of alcohol craving and relapse vulnerability. | Heinz A et al. | β | 2009 | β |
| Modeling stress and drug craving in the laboratory: implications for addiction treatment development. | Sinha R | β | 2009 | β |
| On the biomedicalization of alcoholism. | Berghmans R et al. | β | 2009 | β |
| Orexin/hypocretin signaling at the orexin 1 receptor regulates cue-elicited cocaine-seeking. | Smith RJ et al. | β | 2009 | β |
| Pathological Gambling: Biological and Clinical Considerations. | Topf JL et al. | β | 2009 | β |
| Pavlovian drug discrimination with bupropion as a feature positive occasion setter: substitution by methamphetamine and nicotine, but not cocaine. | Wilkinson JL et al. | β | 2009 | β |
| Persistent proteomic alterations in the medial prefrontal cortex with abstinence from cocaine self-administration. | Lull ME et al. | β | 2009 | β |
| Pharmacogenetic treatments for drug addiction: cocaine, amphetamine and methamphetamine. | Haile CN et al. | β | 2009 | β |
| Role of ventral medial prefrontal cortex in incubation of cocaine craving. | Koya E et al. | β | 2009 | β |
| Role of ventral tegmental area glial cell line-derived neurotrophic factor in incubation of cocaine craving. | Lu L et al. | β | 2009 | β |
| Theories of addiction: methamphetamine users' explanations for continuing drug use and relapse. | Newton TF et al. | β | 2009 | β |
| Up-regulation of AGS3 during morphine withdrawal promotes cAMP superactivation via adenylyl cyclase 5 and 7 in rat nucleus accumbens/striatal neurons. | Fan P et al. | β | 2009 | β |
| [What can addiction research contribute towards the understanding of obesity?]. | Kiefer F et al. | β | 2009 | β |
| A unified framework for addiction: vulnerabilities in the decision process. | Redish AD et al. | β | 2008 | β |
| Beta-endorphin and drug-induced reward and reinforcement. | Roth-Deri I et al. | β | 2008 | β |
| Chronic stress, drug use, and vulnerability to addiction. | Sinha R | β | 2008 | β |
| Chronology of alcohol dependence: implications in prevention. | Manjunatha N et al. | β | 2008 | β |
| Cocaine self-administration reinforced on a progressive ratio schedule decreases with continuous D-amphetamine treatment in rats. | Chiodo KA et al. | β | 2008 | β |
| Communication networks in the brain: neurons, receptors, neurotransmitters, and alcohol. | Lovinger DM | β | 2008 | β |
| Concurrent access to sucrose pellets decreases methamphetamine-seeking behavior in Lewis rats. | Ping A et al. | β | 2008 | β |
| Craving decrease with topiramate in outpatient treatment for cocaine dependence: an open label trial. | Reis AD et al. | β | 2008 | β |
| Drug addiction as a pathology of staged neuroplasticity. | Kalivas PW et al. | β | 2008 | β |
| Effects of naltrexone and acamprosate on alcohol-induced NGFI-A expression in mouse brain. | Lindholm J et al. | β | 2008 | β |
| Evidence for sugar addiction: behavioral and neurochemical effects of intermittent, excessive sugar intake. | Avena NM et al. | β | 2008 | β |
| gamma-Hydroxybutyric acid (GHB) suppresses alcohol's motivational properties in alcohol-preferring rats. | Maccioni P et al. | β | 2008 | β |
| GDNF is a fast-acting potent inhibitor of alcohol consumption and relapse. | Carnicella S et al. | β | 2008 | β |
| Heroin self-administration: II. CNS gene expression following withdrawal and cue-induced drug-seeking behavior. | Kuntz KL et al. | β | 2008 | β |
| Level of operant training rather than cocaine intake predicts level of reinstatement. | Keiflin R et al. | β | 2008 | β |
| Making a bad thing worse: adverse effects of stress on drug addiction. | Cleck JN et al. | β | 2008 | β |
| Medication of l-tetrahydropalmatine significantly ameliorates opiate craving and increases the abstinence rate in heroin users: a pilot study. | Yang Z et al. | β | 2008 | β |
| Naltrexone attenuates the subjective effects of amphetamine in patients with amphetamine dependence. | Jayaram-LindstrΓΆm N et al. | β | 2008 | β |
| Neuroplasticity in the mesolimbic dopamine system and cocaine addiction. | Thomas MJ et al. | β | 2008 | β |
| Persistent alterations in mesolimbic gene expression with abstinence from cocaine self-administration. | Freeman WM et al. | β | 2008 | β |
| Pharmacogenetic treatments for drug addiction: alcohol and opiates. | Haile CN et al. | β | 2008 | β |
| Predicting response to opiate antagonists and placebo in the treatment of pathological gambling. | Grant JE et al. | β | 2008 | β |
| Randomized trial comparing two treatment strategies using prize-based reinforcement of abstinence in cocaine and opiate users. | Preston KL et al. | β | 2008 | β |
| Reversal of cocaine addiction by environmental enrichment. | Solinas M et al. | β | 2008 | β |
| Review. Evidence-based treatments of addiction. | O'Brien CP | β | 2008 | β |
| Review. Positron emission tomography imaging studies of dopamine receptors in primate models of addiction. | Nader MA et al. | β | 2008 | β |
| The formation of a socioeconomic health disparity: the case of cocaine use during the 1980s and 1990s. | Miech R | β | 2008 | β |
| The neurobiology and genetics of impulse control disorders: relationships to drug addictions. | Brewer JA et al. | β | 2008 | β |
| The role of the orbitofrontal cortex in the pursuit of happiness and more specific rewards. | Burke KA et al. | β | 2008 | β |
| A computational model of craving and obsession. | Redish AD et al. | β | 2007 | β |
| A conflict rat model of cue-induced relapse to cocaine seeking. | Cooper A et al. | β | 2007 | β |
| A perfect platform: combining contingency management with medications for drug abuse. | Carroll KM et al. | β | 2007 | β |
| A scale-free systems theory of motivation and addiction. | Chambers RA et al. | β | 2007 | β |
| Consistency of subjective responses to imagery-induced tobacco craving over multiple sessions. | Lee DC et al. | β | 2007 | β |
| Does naltrexone affect craving in abstinent opioid-dependent patients? | Dijkstra BA et al. | β | 2007 | β |
| Does response-contingent access to cocaine reinstate previously extinguished cocaine-seeking behavior in C57BL/6J mice? | Kruzich PJ | β | 2007 | β |
| Dynorphin and the pathophysiology of drug addiction. | Shippenberg TS et al. | β | 2007 | β |
| Dysfunction of reward processing correlates with alcohol craving in detoxified alcoholics. | Wrase J et al. | β | 2007 | β |
| Effects of two novel D3-selective compounds, NGB 2904 [N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-9H-fluorene-2-carboxamide] and CJB 090 [N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-4-(pyridin-2-yl)benzamide], on the reinforcing and discriminative stimulus effects of cocaine in rhesus monkeys. | Martelle JL et al. | β | 2007 | β |
| Endocannabinoid regulation of relapse mechanisms. | Fattore L et al. | β | 2007 | β |
| Gender and stimulus difference in cue-induced responses in abstinent heroin users. | Yu J et al. | β | 2007 | β |
| Genetics of dopamine and its contribution to cocaine addiction. | Haile CN et al. | β | 2007 | β |
| Interest for delivery of cocaethylene in a sustained release emulsion vs saline evaluated on behavioral sensitization in naive and cocaine-sensitized mice. | Noble F et al. | β | 2007 | β |
| Interventions to reduce harm associated with adolescent substance use. | Toumbourou JW et al. | β | 2007 | β |
| Long-term housing and work outcomes among treated cocaine-dependent homeless persons. | Kertesz SG et al. | β | 2007 | β |
| Neurobiology of cocaine addiction: implications for new pharmacotherapy. | Kalivas PW | β | 2007 | β |
| New developments in the pharmacotherapy of cocaine abuse. | Preti A | β | 2007 | β |
| Outpatient Long-term Intensive Therapy for Alcoholics (OLITA): a successful biopsychosocial approach to the treatment of alcoholism. | Krampe H et al. | β | 2007 | β |
| Overview of the pharmacogenomics of cigarette smoking. | Ho MK et al. | β | 2007 | β |
| Presynaptic delta opioid receptors regulate ethanol actions in central amygdala. | Kang-Park MH et al. | β | 2007 | β |
| Psychosocial approaches to psychostimulant dependence: a systematic review. | Shearer J | β | 2007 | β |
| The influence of reinforcing effects of cocaine on cocaine-induced increases in extinguished responding in cynomolgus monkeys. | Banks ML et al. | β | 2007 | β |
| The role of stress in addiction relapse. | Sinha R | β | 2007 | β |
| [Cue-induced alcohol craving. Neurobiological correlates and clinical relevance]. | Wrase J et al. | β | 2006 | β |
| Development of a mouse model of ethanol addiction: naltrexone efficacy in reducing consumption but not craving. | Fachin-Scheit DJ et al. | β | 2006 | β |
| Disulfiram for cocaine dependence. | Cubells JF | β | 2006 | β |
| Emotion-based decision-making in healthy subjects: short-term effects of reducing dopamine levels. | Sevy S et al. | β | 2006 | β |
| Evidenced-based treatment of opioid-dependent patients. | Van den Brink W et al. | β | 2006 | β |
| Increased vulnerability to nicotine self-administration and relapse in alcohol-naive offspring of rats selectively bred for high alcohol intake. | LΓͺ AD et al. | β | 2006 | β |
| Loosening addiction's deadly grip. Recent research paints a picture of addiction as a progressive, chronic neurological disease that wreaks havoc with brain chemistry. | Brower V | β | 2006 | β |
| Medical education and treatment of addictive disorders. | O'Brien CP | β | 2006 | β |
| Naltrexone inhibits alcohol-mediated enhancement of HIV infection of T lymphocytes. | Wang X et al. | β | 2006 | β |
| Pharmacotherapy for alcohol dependence: anticraving medications for relapse prevention. | Jung YC et al. | β | 2006 | β |
| Regarding articles on nicotine and cocaine dependence. | Oyemade A | β | 2006 | β |
| Review of the pharmacology and clinical profile of bupropion, an antidepressant and tobacco use cessation agent. | Dwoskin LP et al. | β | 2006 | β |
| Role of ERK in cocaine addiction. | Lu L et al. | β | 2006 | β |
| Toward a model of drug relapse: an assessment of the validity of the reinstatement procedure. | Epstein DH et al. | β | 2006 | β |
| Critical assessment of how to study addiction and its treatment: human and non-human animal models. | O'Brien CP et al. | β | 2005 | β |
| Efficacy and tolerability of long-acting injectable naltrexone for alcohol dependence. | O'Brien CP | β | 2005 | β |
| Neurobiology of addiction: treatment and public policy ramifications. | Dackis C et al. | β | 2005 | β |
| The role of neuroadaptations in relapse to drug seeking. | Shaham Y et al. | β | 2005 | β |