Reduced cerebral grey matter observed in alcoholics using magnetic resonance imaging.
paper
Cited
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- Authors
- Jernigan, T L; Butters, N; DiTraglia, G; Schafer, K; Smith, T; Irwin, M; Grant, I; Schuckit, M; Cermak, L S
- Year
- 1991
- Journal
- Alcoholism, clinical and experimental research
- PMID
- 1877728
- DOI
- 10.1111/j.1530-0277.1991.tb00540.x
Twenty-eight chronic alcoholics and 36 age- and sex-matched non-alcoholic controls were examined with magnetic resonance imaging and brain morphometric analyses. Results confirmed large increases in subarachnoid cerebrospinal fluid (CSF) volume and mild ventricular enlargement in the alcoholics and revealed associated volume reductions of localized cortical and subcortical cerebral structures. Volume losses in the diencephalon, the caudate nucleus, dorsolateral frontal and parietal cortex, and mesial temporal lobe structures were the most prominent. Significant correlations between increments in cortical and ventricular CSF and decrements in the volume of cortical and subcortical grey matter were noted. Although there was little evidence for relationships between performance on neuropsychological tests and volume of grey matter structures, significant correlations between some cognitive measures and subcortical and cortical fluid volumes were found. The parallels between this pattern of affected structures and recent neuropathological findings are discussed.
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| Alcohol, flexible behavior, and the prefrontal cortex: Functional changes underlying impaired cognitive flexibility. | Nippert KE et al. | — | 2024 | → |
| Functional and morphological adaptation of medial prefrontal corticotropin releasing factor receptor 1-expressing neurons in male mice following chronic ethanol exposure. | Patel RR et al. | — | 2024 | → |
| Alcohol use disorder: Neuroimaging evidence for accelerated aging of brain morphology and hypothesized contribution to age-related dementia. | Sullivan EV et al. | — | 2023 | → |
| Arcuate Fasciculus Microstructure Predicts Alcohol Dependence Risk through Higher IQ. | Ikuta T et al. | — | 2023 | → |
| Cerebral cortical structural alteration patterns across four major psychiatric disorders in 5549 individuals. | Matsumoto J et al. | — | 2023 | → |
| Functional and Structural Brain Abnormalities and Clinical Characteristics of Male Patients with Alcohol Dependence. | Park SE et al. | — | 2023 | → |
| Sensitivity of Hypocretin System to Chronic Alcohol Exposure: A Human and Animal Study. | McGregor R et al. | — | 2023 | → |
| Ethanol withdrawal-induced adaptations in prefrontal corticotropin releasing factor receptor 1-expressing neurons regulate anxiety and conditioned rewarding effects of ethanol. | Patel RR et al. | — | 2022 | → |
| Neuroimaging in alcohol use disorder: From mouse to man. | Fritz M et al. | — | 2022 | → |
| A genome-wide association study of interhemispheric theta EEG coherence: implications for neural connectivity and alcohol use behavior. | Meyers JL et al. | — | 2021 | → |
| Association between Changes in Cortical Thickness and Functional Connectivity in Male Patients with Alcohol-dependence. | Park SE et al. | — | 2021 | → |
| Lithium prevents grey matter atrophy in patients with bipolar disorder: an international multicenter study. | Hozer F et al. | — | 2021 | → |
| The effects of peri-adolescent alcohol use on the developing hippocampus. | Walker CD et al. | — | 2021 | → |
| Alcohol and Dementia - What is the Link? A Systematic Review. | Wiegmann C et al. | — | 2020 | → |
| A multimodal neuroimaging classifier for alcohol dependence. | Guggenmos M et al. | — | 2020 | → |
| Association of Polygenic Liability for Alcohol Dependence and EEG Connectivity in Adolescence and Young Adulthood. | Meyers JL et al. | — | 2019 | → |
| Brain Structure Alterations in Poly-Drug Use: Reduced Cortical Thickness and White Matter Impairments in Regions Associated With Affective, Cognitive, and Motor Functions. | Unterrainer HF et al. | — | 2019 | → |
| Effect of Alcohol on Hippocampal-Dependent Plasticity and Behavior: Role of Glutamatergic Synaptic Transmission. | Mira RG et al. | — | 2019 | → |
| Exercise-driven restoration of the alcohol-damaged brain. | West RK et al. | — | 2019 | → |
| Its complicated: The relationship between alcohol and microglia in the search for novel pharmacotherapeutic targets for alcohol use disorders. | Melbourne JK et al. | — | 2019 | → |
| ADX-47273, a mGlu5 receptor positive allosteric modulator, attenuates deficits in cognitive flexibility induced by withdrawal from 'binge-like' ethanol exposure in rats. | Marszalek-Grabska M et al. | — | 2018 | → |
| Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group. | Hibar DP et al. | — | 2018 | → |
| The Aging Brain With HIV Infection: Effects of Alcoholism or Hepatitis C Comorbidity. | Zahr NM | — | 2018 | → |
| The Impact of Alcohol Use on Frontal White Matter in HIV. | Gullett JM et al. | — | 2018 | → |
| Alcohol's Effects on the Brain: Neuroimaging Results in Humans and Animal Models. | Zahr NM et al. | — | 2017 | → |
| Alcohol use is associated with thinner cerebral cortex and larger ventricles in schizophrenia, bipolar disorder and healthy controls. | Lange EH et al. | — | 2017 | → |
| Cannabis-associated psychosis: Neural substrate and clinical impact. | Murray RM et al. | — | 2017 | → |
| Perspectives on fronto-fugal circuitry from human imaging of alcohol use disorders. | Zahr NM et al. | — | 2017 | → |
| Quantitative neurobiological evidence for accelerated brain aging in alcohol dependence. | Guggenmos M et al. | — | 2017 | → |
| Does history of substance use disorder predict acute traumatic brain injury rehabilitation outcomes? | Niemeier JP et al. | — | 2016 | → |
| GATA4 variant interaction with brain limbic structure and relapse risk: A voxel-based morphometry study. | Zois E et al. | — | 2016 | → |
| Genetic imaging consortium for addiction medicine: From neuroimaging to genes. | Mackey S et al. | — | 2016 | → |
| Subcortical volumetric abnormalities in bipolar disorder. | Hibar DP et al. | — | 2016 | → |
| Abnormal reward functioning across substance use disorders and major depressive disorder: Considering reward as a transdiagnostic mechanism. | Baskin-Sommers AR et al. | — | 2015 | → |
| An Update of the Review of Neuropsychological Consequences of HIV and Substance Abuse: A Literature Review and Implications for Treatment and Future Research. | Norman LR et al. | — | 2015 | → |
| Chronic ethanol consumption profoundly alters regional brain ceramide and sphingomyelin content in rodents. | Roux A et al. | — | 2015 | → |
| Daily marijuana use is not associated with brain morphometric measures in adolescents or adults. | Weiland BJ et al. | — | 2015 | → |
| Effects of aging on frontal white matter microstructure in alcohol use disorder and associations with processing speed. | Sorg SF et al. | — | 2015 | → |
| Protracted abstinence from chronic ethanol exposure alters the structure of neurons and expression of oligodendrocytes and myelin in the medial prefrontal cortex. | Navarro AI et al. | — | 2015 | → |
| Thalamic abnormalities are a cardinal feature of alcohol-related brain dysfunction. | Pitel AL et al. | — | 2015 | → |
| Theory of mind difficulties in patients with alcohol dependence: beyond the prefrontal cortex dysfunction hypothesis. | Maurage F et al. | — | 2015 | → |
| Association between gray matter volume in the caudate nucleus and financial extravagance: findings from voxel-based morphometry. | Yokoyama R et al. | — | 2014 | → |
| Changes in cerebral morphometry and amplitude of low-frequency fluctuations of BOLD signals during healthy aging: correlation with inhibitory control. | Hu S et al. | — | 2014 | → |
| Database of normal Japanese gray matter volumes in the default mode network. | Goto M et al. | — | 2014 | → |
| GABA-A and NMDA receptor subunit mRNA expression is altered in the caudate but not the putamen of the postmortem brains of alcoholics. | Bhandage AK et al. | — | 2014 | → |
| Impact of alcohol consumption in healthy adults: a magnetic resonance imaging investigation. | Preti A et al. | — | 2014 | → |
| Recognition of facial expressions by alcoholic patients: a systematic literature review. | Donadon MF et al. | — | 2014 | → |
| Selective increases of AMPA, NMDA, and kainate receptor subunit mRNAs in the hippocampus and orbitofrontal cortex but not in prefrontal cortex of human alcoholics. | Jin Z et al. | — | 2014 | → |
| Structural and microstructral imaging of the brain in alcohol use disorders. | Zahr NM | — | 2014 | → |
| Deficits in cortical, diencephalic and midbrain gray matter in alcoholism measured by VBM: Effects of co-morbid substance abuse. | Grodin EN et al. | — | 2013 | → |
| How does ethanol induce apoptotic cell death of SK-N-SH neuroblastoma cells. | Moon Y et al. | — | 2013 | → |
| Readiness to change and brain damage in patients with chronic alcoholism. | Le Berre AP et al. | — | 2013 | → |
| Reduced limbic metabolism and fronto-cortical volume in rats vulnerable to alcohol addiction. | Gozzi A et al. | — | 2013 | → |
| The neurobiology of successful abstinence. | Garavan H et al. | — | 2013 | → |
| White matter microstructure alterations: a study of alcoholics with and without post-traumatic stress disorder. | Durkee CA et al. | — | 2013 | → |
| Association of genetic copy number variations at 11 q14.2 with brain regional volume differences in an alcohol use disorder population. | Boutte D et al. | — | 2012 | → |
| Frontal white matter integrity predictors of adult alcohol treatment outcome. | Sorg SF et al. | — | 2012 | → |
| Function and dysfunction of prefrontal brain circuitry in alcoholic Korsakoff's syndrome. | Oscar-Berman M | — | 2012 | → |
| Loss of dopamine D2 receptors induces atrophy in the temporal and parietal cortices and the caudal thalamus of ethanol-consuming mice. | Delis F et al. | — | 2012 | → |
| Regional brain structural dysmorphology in human immunodeficiency virus infection: effects of acquired immune deficiency syndrome, alcoholism, and age. | Pfefferbaum A et al. | — | 2012 | → |
| Relationship between carbohydrate-deficient transferrin, gamma-glutamyl transferase, and mean corpuscular volume levels and alcohol-related brain volume decreases in male drinkers. | de Bruin EA et al. | — | 2012 | → |
| Relationship between liver function and brain shrinkage in patients with alcohol dependence. | Chen CH et al. | — | 2012 | → |
| 3 Tesla MRI detects accelerated hippocampal volume reduction in postmenopausal women. | Goto M et al. | — | 2011 | → |
| Alcohol and the human brain: a systematic review of different neuroimaging methods. | Bühler M et al. | — | 2011 | → |
| A mathematical formula for prediction of gray and white matter volume recovery in abstinent alcohol dependent individuals. | Mon A et al. | — | 2011 | → |
| Association of frontal and posterior cortical gray matter volume with time to alcohol relapse: a prospective study. | Rando K et al. | — | 2011 | → |
| Changes in neuropsychological functioning over 10 years following adolescent substance abuse treatment. | Hanson KL et al. | — | 2011 | → |
| Clinical and pathological features of alcohol-related brain damage. | Zahr NM et al. | — | 2011 | → |
| Disruption of functional connectivity of the default-mode network in alcoholism. | Chanraud S et al. | — | 2011 | → |
| Entorhinal cortex volume measured with 3T MRI is positively correlated with the Wechsler Memory Scale-Revised logical/verbal memory score for healthy subjects. | Goto M et al. | — | 2011 | → |
| Independent contributions of cortical gray matter, aging, sex and alcoholism to K-complex amplitude evoked during sleep. | Colrain IM et al. | — | 2011 | → |
| Reduced cortical thickness in abstinent alcoholics and association with alcoholic behavior. | Fortier CB et al. | — | 2011 | → |
| Selective Changes of GABA(A) Channel Subunit mRNAs in the Hippocampus and Orbitofrontal Cortex but not in Prefrontal Cortex of Human Alcoholics. | Jin Z et al. | — | 2011 | → |
| Subcortical volumes in long-term abstinent alcoholics: associations with psychiatric comorbidity. | Sameti M et al. | — | 2011 | → |
| Age-related gray matter shrinkage in a treatment naïve actively drinking alcohol-dependent sample. | Fein G et al. | — | 2010 | → |
| Alcohol and the prefrontal cortex. | Abernathy K et al. | — | 2010 | → |
| Association of SOD2, a mitochondrial antioxidant enzyme, with gray matter volume shrinkage in alcoholics. | Srivastava V et al. | — | 2010 | → |
| Dual tasking and working memory in alcoholism: relation to frontocerebellar circuitry. | Chanraud S et al. | — | 2010 | → |
| Ethanol self-administration modulation of NMDA receptor subunit and related synaptic protein mRNA expression in prefrontal cortical fields in cynomolgus monkeys. | Acosta G et al. | — | 2010 | → |
| Extinction of drug- and withdrawal-paired cues in animal models: relevance to the treatment of addiction. | Myers KM et al. | — | 2010 | → |
| Impulsivity-related brain volume deficits in schizophrenia-addiction comorbidity. | Schiffer B et al. | — | 2010 | → |
| Insular cortex morphometry in first-episode schizophrenia-spectrum patients: Diagnostic specificity and clinical correlations. | Crespo-Facorro B et al. | — | 2010 | → |
| Learning and memory performances in adolescent users of alcohol and marijuana: interactive effects. | Mahmood OM et al. | — | 2010 | → |
| Transcallosal white matter degradation detected with quantitative fiber tracking in alcoholic men and women: selective relations to dissociable functions. | Pfefferbaum A et al. | — | 2010 | → |
| Biologic Commonalities between Mental Illness and Addiction. | Hartwell KJ et al. | — | 2009 | → |
| Comorbid substance abuse and brain morphology in recent-onset psychosis. | Wobrock T et al. | — | 2009 | → |
| Degradation of association and projection white matter systems in alcoholism detected with quantitative fiber tracking. | Pfefferbaum A et al. | — | 2009 | → |
| Dose-dependent frontal hypometabolism on FDG-PET in methamphetamine abusers. | Kim YT et al. | — | 2009 | → |
| Episodic memory in detoxified alcoholics: contribution of grey matter microstructure alteration. | Chanraud S et al. | — | 2009 | → |
| Frontal and cingulate gray matter volume reduction in heroin dependence: optimized voxel-based morphometry. | Liu H et al. | — | 2009 | → |
| Global-local interference is related to callosal compromise in alcoholism: a behavior-DTI association study. | Müller-Oehring EM et al. | — | 2009 | → |
| Imaging of language-related brain regions in detoxified alcoholics. | Chanraud-Guillermo S et al. | — | 2009 | → |
| Increased white matter signal hyperintensities in long-term abstinent alcoholics compared with nonalcoholic controls. | Fein G et al. | — | 2009 | → |
| Morphological and glucose metabolism abnormalities in alcoholic Korsakoff's syndrome: group comparisons and individual analyses. | Pitel AL et al. | — | 2009 | → |
| Neuroimaging of the Wernicke-Korsakoff syndrome. | Sullivan EV et al. | — | 2009 | → |
| Neuropsychological consequences of HIV and substance abuse: a literature review and implications for treatment and future research. | Norman LR et al. | — | 2009 | → |
| Proteomics approach in the study of the pathophysiology of alcohol-related brain damage. | Matsumoto I | — | 2009 | → |
| Specific brain structural abnormalities in first-episode schizophrenia. A comparative study with patients with schizophreniform disorder, non-schizophrenic non-affective psychoses and healthy volunteers. | Crespo-Facorro B et al. | — | 2009 | → |
| The impact of chronic cigarette smoking on recovery from cortical gray matter perfusion deficits in alcohol dependence: longitudinal arterial spin labeling MRI. | Mon A et al. | — | 2009 | → |
| White matter integrity in adolescents with histories of marijuana use and binge drinking. | Jacobus J et al. | — | 2009 | → |
| Alcoholism: protein expression profiles in a human hippocampal model. | Matsumoto H et al. | — | 2008 | → |
| Customization of normal data base specific for 3-tesla MRI is mandatory in VSRAD analysis. | Goto M et al. | — | 2008 | → |
| Delay discrimination and reversal eyeblink classical conditioning in abstinent chronic alcoholics. | Fortier CB et al. | — | 2008 | → |
| Light to moderate alcohol use is associated with increased cortical gray matter in middle-aged men: a voxel-based morphometric study. | Sachdev PS et al. | — | 2008 | → |
| Magnetic resonance imaging of the living brain: evidence for brain degeneration among alcoholics and recovery with abstinence. | Rosenbloom MJ et al. | — | 2008 | → |
| Neuroinflammation as a neurotoxic mechanism in alcoholism: commentary on "Increased MCP-1 and microglia in various regions of human alcoholic brain". | Sullivan EV et al. | — | 2008 | → |
| Neuropathology of alcohol-related cognitive alterations. | Harper C et al. | — | 2008 | → |
| Social cognition in alcoholism: a link to prefrontal cortex dysfunction? | Uekermann J et al. | — | 2008 | → |
| Tobacco smoking and MRI/MRS brain abnormalities compared to nonsmokers. | Domino EF | — | 2008 | → |
| Ventricular expansion in wild-type Wistar rats after alcohol exposure by vapor chamber. | Pfefferbaum A et al. | — | 2008 | → |
| Brain morphometry and cognitive performance in detoxified alcohol-dependents with preserved psychosocial functioning. | Chanraud S et al. | — | 2007 | → |
| CNS proteomes in alcohol and drug abuse and dependence. | Matsumoto I et al. | — | 2007 | → |
| Deformation-based morphometry of brain changes in alcohol dependence and abstinence. | Cardenas VA et al. | — | 2007 | → |
| Development and resolution of brain lesions caused by pyrithiamine- and dietary-induced thiamine deficiency and alcohol exposure in the alcohol-preferring rat: a longitudinal magnetic resonance imaging and spectroscopy study. | Pfefferbaum A et al. | — | 2007 | → |
| Hierarchical linear modeling (HLM) of longitudinal brain structural and cognitive changes in alcohol-dependent individuals during sobriety. | Yeh PH et al. | — | 2007 | → |
| Parental alcohol use and brain volumes in early- and late-onset alcoholics. | Gilman JM et al. | — | 2007 | → |
| Both global gray matter volume and regional gray matter volume negatively correlate with lifetime alcohol intake in non-alcohol-dependent Japanese men: a volumetric analysis and a voxel-based morphometry. | Taki Y et al. | — | 2006 | → |
| Contribution of alcoholism to brain dysmorphology in HIV infection: effects on the ventricles and corpus callosum. | Pfefferbaum A et al. | — | 2006 | → |
| Cortical gamma-aminobutyric acid levels and the recovery from ethanol dependence: preliminary evidence of modification by cigarette smoking. | Mason GF et al. | — | 2006 | → |
| Effect of vision, touch and stance on cerebellar vermian-related sway and tremor: a quantitative physiological and MRI study. | Sullivan EV et al. | — | 2006 | → |
| Ethanol-induced regulation of GABA-A subunit mRNAs in prefrontal fields of cynomolgus monkeys. | Hemby SE et al. | — | 2006 | → |
| Longitudinal brain magnetic resonance imaging study of the alcohol-preferring rat. Part II: effects of voluntary chronic alcohol consumption. | Pfefferbaum A et al. | — | 2006 | → |
| Neuropsychological and sensory gating deficits related to remote alcohol abuse history in schizophrenia. | Thoma RJ et al. | — | 2006 | → |
| On blending practice and research: the search for commonalities in substance abuse treatment. | Kellogg S et al. | — | 2006 | → |
| Adolescence: booze, brains, and behavior. | Monti PM et al. | — | 2005 | → |
| Alcoholic neurobiology: changes in dependence and recovery. | Crews FT et al. | — | 2005 | → |
| Applications of morphometric and diffusion tensor magnetic resonance imaging to the study of brain abnormalities in the alcoholism spectrum. | Daurignac E et al. | — | 2005 | → |
| Associations between alcohol intake and brain volumes in male and female moderate drinkers. | de Bruin EA et al. | — | 2005 | → |
| Chronic active heavy drinking and family history of problem drinking modulate regional brain tissue volumes. | Cardenas VA et al. | — | 2005 | → |
| Genetic influences in emotional dysfunction and alcoholism-related brain damage. | Oscar-Berman M et al. | — | 2005 | → |
| Health risks of chronic moderate and heavy alcohol consumption: how much is too much? | Meyerhoff DJ et al. | — | 2005 | → |
| Magnetic resonance imaging (MRI) measurement of hippocampal volume in posttraumatic stress disorder: a meta-analysis. | Kitayama N et al. | — | 2005 | → |
| Neurocircuitry in alcoholism: a substrate of disruption and repair. | Sullivan EV et al. | — | 2005 | → |
| Neuroimaging of gender differences in alcohol dependence: are women more vulnerable? | Mann K et al. | — | 2005 | → |
| Neuroprotective and abstinence-promoting effects of acamprosate: elucidating the mechanism of action. | De Witte P et al. | — | 2005 | → |
| Striatal dopamine D1 receptors in type 1 and 2 alcoholics measured with human whole hemisphere autoradiography. | Tupala E et al. | — | 2005 | → |
| The diagnostic value of tau protein, beta-amyloid (1-42) and their ratio for the discrimination of alcohol-related cognitive disorders from Alzheimer's disease in the early stages. | Kapaki E et al. | — | 2005 | → |
| The effect of moderate to severe traumatic brain injury (TBI) on different aspects of memory: a selective review. | Vakil E | — | 2005 | → |
| The neuropsychological profile of alcohol-related dementia suggests cortical and subcortical pathology. | Schmidt KS et al. | — | 2005 | → |
| Trace eyeblink conditioning in abstinent alcoholic individuals: effects of complex task demands and prior conditioning. | McGlinchey RE et al. | — | 2005 | → |
| Dopamine and alcoholism: neurobiological basis of ethanol abuse. | Tupala E et al. | — | 2004 | → |
| [Neuroimaging in substance abuse disorders]. | de Mendelssohn A et al. | — | 2004 | → |
| Perceptual learning in detoxified alcoholic men: contributions from explicit memory, executive function, and age. | Fama R et al. | — | 2004 | → |
| Reduction of Purkinje cell volume in cerebellum of alcoholics. | Andersen BB | — | 2004 | → |
| Voxel-based morphometry of human brain with age and cerebrovascular risk factors. | Taki Y et al. | — | 2004 | → |
| Compromised pontocerebellar and cerebellothalamocortical systems: speculations on their contributions to cognitive and motor impairment in nonamnesic alcoholism. | Sullivan EV | — | 2003 | → |
| CSF monoamine metabolites and MRI brain volumes in alcohol dependence. | Agartz I et al. | — | 2003 | → |
| Electrophysiological evidence of abnormal activation of the cerebral network of involuntary attention in alcoholism. | Polo MD et al. | — | 2003 | → |
| Enhanced release from proactive interference in nonamnesic alcoholic individuals: implications for impaired associative binding. | De Rosa E et al. | — | 2003 | → |
| How important are brain banks for alcohol research? | Harper C et al. | — | 2003 | → |
| Magnetic resonance imaging studies on autism and childhood-onset schizophrenia in children and adolescents - a review. | Lahuis B et al. | — | 2003 | → |
| Neuropathological alterations in alcoholic brains. Studies arising from the New South Wales Tissue Resource Centre. | Harper C et al. | — | 2003 | → |
| Reduced olfactory sensitivity, discrimination, and identification in patients with alcohol dependence. | Rupp CI et al. | — | 2003 | → |
| Using magnetic resonance imaging and diffusion tensor imaging to assess brain damage in alcoholics. | Rosenbloom M et al. | — | 2003 | → |
| Alcoholism and AIDS: magnetic resonance imaging approaches for detecting interactive neuropathology. | Pfefferbaum A et al. | — | 2002 | → |
| Brain morphometry in female victims of intimate partner violence with and without posttraumatic stress disorder. | Fennema-Notestine C et al. | — | 2002 | → |
| Cortical gray matter loss in treatment-naïve alcohol dependent individuals. | Fein G et al. | — | 2002 | → |
| Drug addiction and its underlying neurobiological basis: neuroimaging evidence for the involvement of the frontal cortex. | Goldstein RZ et al. | — | 2002 | → |
| Individual differences in latent neuropsychological abilities at addictions treatment entry. | Bates ME et al. | — | 2002 | → |
| Neurocognitive impairment associated with alcohol use disorders: implications for treatment. | Bates ME et al. | — | 2002 | → |
| Prefrontal volumes in habitually violent subjects with antisocial personality disorder and type 2 alcoholism. | Laakso MP et al. | — | 2002 | → |
| Temporal discrimination learning in abstinent chronic alcoholics. | McGlinchey-Berroth R et al. | — | 2002 | → |
| Auditory P3a deficits in male subjects at high risk for alcoholism. | Hada M et al. | — | 2001 | → |
| Effects of abstinence from alcohol on the broad phospholipid signal in human brain: an in vivo 31P magnetic resonance spectroscopy study. | Estilaei MR et al. | — | 2001 | → |
| Effects of abstinence on the brain: quantitative magnetic resonance imaging and magnetic resonance spectroscopic imaging in chronic alcohol abuse. | O'Neill J et al. | — | 2001 | → |
| Evidence for a gender-related effect of alcoholism on brain volumes. | Hommer D et al. | — | 2001 | → |
| fMRI measurement of brain dysfunction in alcohol-dependent young women. | Tapert SF et al. | — | 2001 | → |
| Separate and interactive effects of cocaine and alcohol dependence on brain structures and metabolites: quantitative MRI and proton MR spectroscopic imaging. | O'Neill J et al. | — | 2001 | → |
| Sex differences in the effects of alcohol on brain structure. | Pfefferbaum A et al. | — | 2001 | → |
| Working memory impairments in alcohol-dependent participants without clinical amnesia. | Ambrose ML et al. | — | 2001 | → |
| Auditory P3a assessment of male alcoholics. | Hada M et al. | — | 2000 | → |
| Binge ethanol consumption causes differential brain damage in young adolescent rats compared with adult rats. | Crews FT et al. | — | 2000 | → |
| Chronic, but not acute, nicotine exposure attenuates ethanol withdrawal-induced hippocampal damage in vitro. | Prendergast MA et al. | — | 2000 | → |
| Elevated myo-inositol in gray matter of recently detoxified but not long-term abstinent alcoholics: a preliminary MR spectroscopy study. | Schweinsburg BC et al. | — | 2000 | → |
| Hippocampal volume in adolescent-onset alcohol use disorders. | De Bellis MD et al. | — | 2000 | → |
| In vitro effects of ethanol withdrawal and spermidine on viability of hippocampus from male and female rat. | Prendergast MA et al. | — | 2000 | → |
| In vivo detection and functional correlates of white matter microstructural disruption in chronic alcoholism. | Pfefferbaum A et al. | — | 2000 | → |
| Neurobehavioural consequences of substance abuse and HIV infection. | Basso MR et al. | — | 2000 | → |
| Neurocognitive functioning of adolescents: effects of protracted alcohol use. | Brown SA et al. | — | 2000 | → |
| Brain shrinkage in alcoholics: a decade on and what have we learned? | Kril JJ et al. | — | 1999 | → |
| Cognitive impairment and cerebral atrophy in "heavy drinkers". | Ratti MT et al. | — | 1999 | → |
| Cortical metabolite alterations in abstinent cocaine and cocaine/alcohol-dependent subjects: proton magnetic resonance spectroscopic imaging. | Meyerhoff DJ et al. | — | 1999 | → |
| Does an increase in sulcal or ventricular fluid predict where brain tissue is lost? | Symonds LL et al. | — | 1999 | → |
| Hypoperfusion of the cerebellum and aging effects on cerebral cortex blood flow in abstinent alcoholics: a SPECT study. | Harris GJ et al. | — | 1999 | → |
| In vivo mammillary body volume deficits in amnesic and nonamnesic alcoholics. | Sullivan EV et al. | — | 1999 | → |
| Structural and functional neuroimaging findings in substance-related disorders. | Netrakom P et al. | — | 1999 | → |
| Suppression of mismatch negativity by backward masking predicts impaired working-memory performance in alcoholics. | Ahveninen J et al. | — | 1999 | → |
| Abstinent chronic crack-cocaine and crackcocaine/alcohol abusers evidence normal hippocampal volumes on MRI despite persistent cognitive impairments. | DI Sclafani V et al. | — | 1998 | → |
| Brain imaging in alcoholism. | Estruch R et al. | — | 1998 | → |
| Patterns of regional cortical dysmorphology distinguishing schizophrenia and chronic alcoholism. | Sullivan EV et al. | — | 1998 | → |
| Reduced levels of GABA-benzodiazepine receptor in alcohol dependency in the absence of grey matter atrophy. | Lingford-Hughes AR et al. | — | 1998 | → |
| Volumetric analysis of white matter, gray matter, and CSF using fractional volume analysis. | Bedell BJ et al. | — | 1998 | → |
| Atrophy of the corpus callosum in chronic alcoholism. | Estruch R et al. | — | 1997 | → |
| Brain impairment in well-nourished chronic alcoholics is related to ethanol intake. | Nicolás JM et al. | — | 1997 | → |
| Cortical and subcortical white matter damage without Wernicke's encephalopathy after recovery from thiamine deficiency in the rat. | Langlais PJ et al. | — | 1997 | → |
| Do chronic alcoholics have intact implicit memory? An ERP study. | Zhang XL et al. | — | 1997 | → |
| Frontal lobe volume loss observed with magnetic resonance imaging in older chronic alcoholics. | Pfefferbaum A et al. | — | 1997 | → |
| Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse--a preliminary report. | Bremner JD et al. | — | 1997 | → |
| The anatomy of mood disorders--review of structural neuroimaging studies. | Soares JC et al. | — | 1997 | → |
| The cerebral cortex is damaged in chronic alcoholics. | Kril JJ et al. | — | 1997 | → |
| Brain metabolite changes in alcoholism: an in vivo proton magnetic resonance spectroscopy (MRS) study. | Jagannathan NR et al. | — | 1996 | → |
| Effects of disulfiram on positron emission tomography and neuropsychological studies in severe chronic alcoholism. | Gilman S et al. | — | 1996 | → |
| Mammillary body and cerebellar shrinkage in chronic alcoholics with and without amnesia. | Shear PK et al. | — | 1996 | → |
| Neuropathology of thiamine deficiency: an update on the comparative analysis of human disorders and experimental models. | Langlais PJ et al. | — | 1996 | → |
| Proliferation of astroglia from the adult human cerebrum is inhibited by ethanol in vitro. | Kane CJ et al. | — | 1996 | → |
| Relation between executive cognitive functioning and the adverse consequences of alcohol use in social drinkers. | Giancola PR et al. | — | 1996 | → |
| Relationship between alcohol withdrawal seizures and temporal lobe white matter volume deficits. | Sullivan EV et al. | — | 1996 | → |
| Single photon emission computed tomography with iodoamphetamine-123 and neuropsychological studies in long-term abstinent alcoholics. | Dupont RM et al. | — | 1996 | → |
| Traumatic brain injury, alcohol and quantitative neuroimaging: preliminary findings. | Bigler ED et al. | — | 1996 | → |
| Anterior hippocampal volume deficits in nonamnesic, aging chronic alcoholics. | Sullivan EV et al. | — | 1995 | → |
| Delayed P3A in abstinent elderly male chronic alcoholics. | Biggins CA et al. | — | 1995 | → |
| Effects of chronic alcohol abuse and HIV infection on brain phosphorus metabolites. | Meyerhoff DJ et al. | — | 1995 | → |
| Imaging Studies of Aging, Neurodegenerative Disease, and Alcoholism. | Eberling JL et al. | — | 1995 | → |
| Impaired delay eyeblink conditioning in amnesic Korsakoff's patients and recovered alcoholics. | McGlinchey-Berroth R et al. | — | 1995 | → |
| Longitudinal changes in magnetic resonance imaging brain volumes in abstinent and relapsed alcoholics. | Pfefferbaum A et al. | — | 1995 | → |
| Magnetic resonance imaging reveals no ventriculomegaly in polydrug abusers. | Liu X et al. | — | 1995 | → |
| Neuroimaging in alcoholism: CT and MRI results and clinical correlates. | Mann K et al. | — | 1995 | → |
| Structural Brain Alterations Associated With Alcoholism. | Rosenbloom MJ et al. | — | 1995 | → |
| Three-dimensional anatomical model-based segmentation of MR brain images through Principal Axes Registration. | Arata LK et al. | — | 1995 | → |
| When Alcoholism Affects Memory Functions: MRI of the Brain. | Jernigan TL et al. | — | 1995 | → |
| Volumetric magnetic resonance imaging quantification of longitudinal brain changes in abstinent alcoholics. | Shear PK et al. | — | 1994 | → |
| Brain lesions in alcoholics. | Charness ME | — | 1993 | → |
| Excitotoxicity and alcohol-related brain damage. | Lovinger DM | — | 1993 | → |
| Neuropsychological deficits are correlated with frontal hypometabolism in positron emission tomography studies of older alcoholic patients. | Adams KM et al. | — | 1993 | → |
| The reversibility of alcoholic brain damage is not due to rehydration: a CT study. | Mann K et al. | — | 1993 | → |
| Alcohol, head injury, and neuropsychological function. | Solomon DA et al. | — | 1992 | → |
| Alzheimer's disease and alcoholism: possible interactions. | Freund G et al. | — | 1992 | → |
| Brain gray and white matter volume loss accelerates with aging in chronic alcoholics: a quantitative MRI study. | Pfefferbaum A et al. | — | 1992 | → |
| Decreased brain metabolism in neurologically intact healthy alcoholics. | Volkow ND et al. | — | 1992 | → |
| Olfactory loss in alcoholics: correlations with cortical and subcortical MRI indices. | Shear PK et al. | — | 1992 | → |
| The contribution of constructional accuracy and organizational strategy to nonverbal recall in schizophrenia and chronic alcoholism. | Sullivan EV et al. | — | 1992 | → |