clusterProfiler 4.0: A universal enrichment tool for interpreting omics data.
paper
Cited
Public
- Authors
- Wu, Tianzhi; Hu, Erqiang; Xu, Shuangbin; Chen, Meijun; Guo, Pingfan; Dai, Zehan; Feng, Tingze; Zhou, Lang; Tang, Wenli; Zhan, Li; Fu, Xiaocong; Liu, Shanshan; Bo, Xiaochen; Yu, Guangchuang
- Year
- 2021
- Journal
- Innovation (Cambridge (Mass.))
- PMID
- 34557778
- DOI
- 10.1016/j.xinn.2021.100141
- PMCID
- PMC8454663
Functional enrichment analysis is pivotal for interpreting high-throughput omics data in life science. It is crucial for this type of tool to use the latest annotation databases for as many organisms as possible. To meet these requirements, we present here an updated version of our popular Bioconductor package, clusterProfiler 4.0. This package has been enhanced considerably compared with its original version published 9 years ago. The new version provides a universal interface for functional enrichment analysis in thousands of organisms based on internally supported ontologies and pathways as well as annotation data provided by users or derived from online databases. It also extends the and packages to offer tidy interfaces for data operation and visualization. Other new features include gene set enrichment analysis and comparison of enrichment results from multiple gene lists. We anticipate that clusterProfiler 4.0 will be applied to a wide range of scenarios across diverse organisms.
Gene ontology enrichment analysisThe original result (A) and a simplified version (B) were visualized as enrichment map networks. Each node represents a gene set (i.e., a GO term) and each edge represents the overlap between two gene sets.
KEGG pathway enrichment analysisIn GSEA enrichment plot (A), the curves represent the running sum of the enrichment scores, the middle part of the graph shows the position of genes that are related to certain pathways, and the bottom part of the graph displays how the metric (e.g., fold change) is distributed along with the list. The UpSet plot (B) visualizes the metric distribution of core enrichment genes. It differentiates genes that uniquely belong to a pathway or are associated with two or more pathways.
Functional enrichment analysis of genomic regions of interestGenomic regions are linked to coding genes, which are then used to identify transcript cofactors by testing significant overlap of target genes.
Comparing functional profiles among different levels of conditionsThe compareCluster function performed enrichment analysis simultaneously for eight lists of DEGs. The results were visualized as a dot plot with an x axis representing one level of conditions (time course) and a facet panel indicating another level of conditions (drug treatments).
Visualizing enrichment results using ggplot2A lollipop chart to visualize the rich factors from ORA (A) and a bar chart to visualize normalized enrichment scores from GSEA (B).
A package suite for mining biological knowledgeclusterProfiler is an essential core for functional analysis, the functionalities of which are enhanced by several companion packages.
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| Gut Associated Metabolites Enhance PD-L1 Blockade Efficacy in Prostate Cancer. | Liu K et al. | — | 2026 | → |
| Gut virome dysbiosis contributes to premature ovarian insufficiency by modulating gut bacteriome. | Jin J et al. | — | 2026 | → |
| Heme Oxygenase-1 Regulates the JAK/STAT Pathway to Inhibit Ferroptosis in Metabolic Dysfunction-Associated Steatotic Liver Disease. | Yao L et al. | — | 2026 | → |
| Heterologous expression and functional characterization of novel microcin B17 congeners from environmental Pseudomonas isolates. | De Smedt S et al. | — | 2026 | → |
| Heterologous Production of Forskolin in Tobacco (Nicotiana tabacum) via Glandular Trichome Specific Engineering and Metabolic Flux Redirection. | Sun X et al. | — | 2026 | → |
| High-CD14-expressing urothelial cancer cells foster a neutrophil-rich tumor microenvironment that increases the risk of radiation-promoted distant metastasis. | Chiang Y et al. | — | 2026 | → |
| High-frequency rTMS mitigates acute sleep deprivation-induced anxiety-like behaviors and working memory impairments associated with hippocampal transcriptional modulation. | Sun Y et al. | — | 2026 | → |
| High-throughput peptide-centric local stability assay extends protein-ligand identification to membrane proteins, tissues and bacteria. | Li K et al. | — | 2026 | → |
| Host adaptation and genome evolution of the broad host range fungal rust pathogen, Austropuccinia psidii. | Luo Z et al. | — | 2026 | → |
| Host microenvironment in potato-Phytophthora infestans interaction revealed by single-cell spatiotemporal transcriptome. | Li Y et al. | — | 2026 | → |
| HPV Integration in Head and Neck Cancer: Downstream Splicing Events and Expression Ratios Linked with Poor Outcomes. | Li S et al. | — | 2026 | → |
| Hybrid endometrial-derived hydrogel and human endometrial organoids synergize for uterine regeneration in an immunocompetent murine model. | Gómez-Álvarez M et al. | — | 2026 | → |
| Identification and characterization of tryptophan metabolism-related genes in carotid artery plaques. | Jia X et al. | — | 2026 | → |
| Identification and mechanistic exploration of VEGFA and CALML3 as calcium channel-related prognostic genes in cervical cancer. | Yang Q et al. | — | 2026 | → |
| Identification and validation of a glutamine metabolism-related gene signature as a diagnostic and therapeutic target in osteoarthritis through integrated multi-omics analysis. | Lu Y et al. | — | 2026 | → |
| Identification of ACBP as a potential target in ciliopathic obesity through multi-omics network analysis. | Corral Nieto Y et al. | — | 2026 | → |
| Identification of Bioactive Compounds and Molecular Targets of Compound Herbs Against Stomach Adenocarcinoma: A Network Pharmacology Approach. | Liu L et al. | — | 2026 | → |
| Identification of Central Genes in the Pathogenesis of Lipid Metabolism in Chronic Lymphocytic Leukaemia: A Multi-Omics Study Integrating Machine Learning and Mendelian Randomisation. | Zhang F et al. | — | 2026 | → |
| Identification of cuproptosis-related subtypes, construction of a prognosis model, and tumor microenvironment landscape in multiple myeloma. | Xu L et al. | — | 2026 | → |
| Identification of early diagnostic biomarkers in venous thromboembolism: A bioinformatic analysis based on crosstalk between pyroptosis and venous thromboembolism. | Han S et al. | — | 2026 | → |
| Identification of Mitochondrial Signature Biomarkers and Molecular Mechanisms in Atherosclerotic Tissues and Blood: Combined Single-Cell and Bulk RNA Sequencing Analysis. | Feng L et al. | — | 2026 | → |
| Identification of mitochondria metabolism-related biomarkers associated with the development of rheumatoid arthritis using bioinformatics: An observational study. | Xu R et al. | — | 2026 | → |
| Identification of O-GlcNAcylation related genes and immune infiltration profile in ischemic stroke utilizing bioinformatics and machine learning. | Liu H et al. | — | 2026 | → |
| Identification of potential drug targets for Alzheimer's disease from genetic insights: A Mendelian randomization study. | Zhao YH et al. | — | 2026 | → |
| Identification of TMEM59L as a potential diagnosis, prognosis and immunotherapy biomarker for colon adenocarcinoma. | Wang W et al. | — | 2026 | → |
| Identifying the potential anti-lung cancer targets of Baicalein using a network pharmacology approach. | Chen X et al. | — | 2026 | → |
| IFDlong: a model-based isoform and fusion detector for accurate annotation and quantification of long-read RNA-seq data. | Wang W et al. | — | 2026 | → |
| Immunomodulatory Mechanism of Baiyaojian Decoction on Periodontitis: Network Pharmacology, Single-Cell RNA Sequencing and Molecular Docking. | Chen BJ et al. | — | 2026 | → |
| Impact of low and high lipopolysaccharide doses on the early expression of immune related genes and transcription factors in chicken macrophage-like HD11 cells. | Jansseune SCG et al. | — | 2026 | → |
| Improved chromosome-level genome assembly of the American cockroach, Periplaneta americana. | Dockman RL et al. | — | 2026 | → |
| Inhibition of CDK8 rescues impaired ischemic fracture healing. | Capobianco CA et al. | — | 2026 | → |
| In mouse and in vitro models, bowel preparation promotes pathogen colonization, translocation, and exacerbation of inflammation. | Clayton CA et al. | — | 2026 | → |
| Insights into karyotype evolution and flower color variation from the genome assembly of wallflower (Erysimum cheiri). | Chen D et al. | — | 2026 | → |
| Integrated analysis of DNA methylation and gene expression in dairy cows during early pregnancy. | Li S et al. | — | 2026 | → |
| Integrated Analysis of Midgut Transcriptome and Microbiome Reveals That Manganese-Induced Dysbiosis Drives Metabolic Disruption and Developmental Toxicity in Bombyx mori. | Xin L et al. | — | 2026 | → |
| Integrated bioinformatic identification and translational validation of key biomarkers and therapeutic candidates for preeclampsia-related acute kidney injury. | Gao L et al. | — | 2026 | → |
| Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer. | Sambath J et al. | — | 2026 | → |
| Integrated microbial and metabolic coordination orchestrates antler growth induced by guar gum and xylo-oligosaccharides. | Li S et al. | — | 2026 | → |
| Integrated Multiomics Analysis and Experimental Validation Identify ITPRIPL1 as an Immunoregulatory and Prognostic Biomarker in Gastric Adenocarcinoma. | Jia Z et al. | — | 2026 | → |
| Integrated multi-omics profiling of plasma extracellular vesicles reveals the hsa-miR-1-3p-LRP1 axis as a potential biomarker in cervical cancer. | Bao T et al. | — | 2026 | → |
| Integrated single-cell multi-omics analysis unveils heterogeneity in the prostate cancer tumor microenvironment. | Mei Z et al. | — | 2026 | → |
| Integrating Mendelian randomization and multi-omics analysis unravels gut microbiota-driven metabolic mechanisms in sepsis and identifies diagnostic biomarkers through experimental validation. | Wang G et al. | — | 2026 | → |
| Integrating multimodal data to identify single nucleotide polymorphism-related biomarkers and regulatory mechanisms in Alzheimer's disease. | Sheng J et al. | — | 2026 | → |
| Integrating single cell- and spatial- resolved transcriptomics unravels the inter-tumor heterogeneity and immunosuppressive landscape in HBV- and Clonorchis sinensis-associated hepatocellular carcinoma. | Chen J et al. | — | 2026 | → |
| Integration of single-cell sequencing, transcriptome sequencing, and machine learning for constructing and validating histone acetylation-related prognostic risk models in hepatocellular carcinoma. | Qi Y et al. | — | 2026 | → |
| Integrative analysis of CUT&Tag-seq and RNA-seq reveals widespread H3K27ac upregulation associated with the activation of muscle-growth-related transcriptional programs in broiler breast muscle. | Cai G et al. | — | 2026 | → |
| Integrative analysis of rumen microbiota and host multi-organ interactions underlying feed conversion efficiency in Hu sheep. | Jia X et al. | — | 2026 | → |
| Integrative analysis of transcriptome and single-cell sequencing combined with experimental validation identifies biomarkers associated with T cell and senescence in sepsis. | Yang K et al. | — | 2026 | → |
| Integrative Application of Transcriptomics and Metabolomics Reveals Molecular Insight into Metabolomic Variations in Chinese Mitten Crab <i>Eriocheir sinensis</i> Harvested from Lake Datong and Adjacent Pond. | Lin L et al. | — | 2026 | → |
| Integrative epigenomic and transcriptomic profiling reveals organ-specific and coordinated cold stress responses in the brain and gill of Nile tilapia. | Li X et al. | — | 2026 | → |
| Integrative Multi-Omics Analysis Reveals Molecular Signatures of Recurrence in Paired Primary and Recurrent High-Grade Serous Ovarian Cancer. | Kim MA et al. | — | 2026 | → |
| Interaction between HIV-1 Tat and EBV Zta favours immune escape of B cells by downregulating HLA-ABC expression. | Shmakova A et al. | — | 2026 | → |
| Interplay between AIB1 genotypes and radiotherapy in a Swedish population-based breast cancer cohort. | Wiberg A et al. | — | 2026 | → |
| Investigating the molecular mechanisms of glutamine metabolism and mitochondria-related biomarkers in Alzheimer's disease through transcriptomics and experimental validation. | Si X et al. | — | 2026 | → |
| Isoflurane and Surgical Stress Disrupt Fatty Acid and Carbon Metabolism, Leading to Cardiomyopathy in Aged Mice. | Yang WW et al. | — | 2026 | → |
| Isoform-Specific Splicing of ANK2 by PTBP2 Orchestrates Retinal Pigment Epithelial-to-Neuron Fate Conversion. | Ma YX et al. | — | 2026 | → |
| Itaconate modulates myeloid inflammation in myocardial infarction via metabolic and structural reprogramming. | Zhang T et al. | — | 2026 | → |
| Key genes of Taohong Siwu decoction in treating coronary heart disease based on network pharmacology and Mendelian randomization. | Wang C et al. | — | 2026 | → |
| KNTC1 and PRC1 define an immunosuppressive microenvironment and poor prognosis in liposarcoma. | Zhang L et al. | — | 2026 | → |
| Lactose-Derived Carbohydrates Induce Sexually Dimorphic Nutritional Programming Effects on Lifespan in Drosophila melanogaster. | Sun P et al. | — | 2026 | → |
| LDHA-driven lactate metabolism promotes MDSC activation and immunosuppressive microenvironment in prostate cancer. | Wei X et al. | — | 2026 | → |
| Leaf transcriptome differences between diploid and tetraploid bahiagrass. | Podio M et al. | — | 2026 | → |
| Lipoprotein(a) and Vascular Redox State in Patients With Advanced Coronary Atherosclerosis. | Polkinghorne MD et al. | — | 2026 | → |
| LncRNA HOXC-AS3 prevents chondrocyte senescence and osteoarthritis progression through miR-615-3p sponging and RRBP1 interaction. | Wang C et al. | — | 2026 | → |
| Local Adaptation and Osmoregulatory Mechanisms of the Copepod Acartia tonsa Under Low Salinity Stress. | Hahn A et al. | — | 2026 | → |
| Low-input proteomics identifies vWF as a negative regulator of Tet2 mutant hematopoietic stem cell expansion. | Jassinskaja M et al. | — | 2026 | → |
| <i>DEprot</i>: a comprehensive R-package for the analysis of label-free quantitation mass spectrometry data. | Eickhoff N et al. | — | 2026 | → |
| <i>EPB41L4A-AS1</i> long noncoding RNA acts in both <i>cis</i>- and <i>trans</i>-acting transcriptional regulation and controls nucleolar biology. | Monziani A et al. | — | 2026 | → |
| <i>ROBO2</i> Variants Associated With Atrial Septal Defect Define a Novel Regulatory Element. | Kim SW et al. | — | 2026 | → |
| <i>SNRK3.15</i> Is a Crucial Component of the Sulfur Deprivation Response in <i>Arabidopsis thaliana</i>. | Apodiakou A et al. | — | 2026 | → |
| M1-linked ubiquitination by LUBAC regulates AMPK signalling and the response to energetic stress. | Elbæk CR et al. | — | 2026 | → |
| MAdLandExpression: integrating sexual reproduction into the Physcomitrium patens expression atlas. | Sanchez-Vera V et al. | — | 2026 | → |
| Male obesity causes adipose mitochondrial dysfunction in F<sub>1</sub> mouse progeny via a let-7-DICER axis. | Huang C et al. | — | 2026 | → |
| Mapping somatosensory afferent circuitry to bone identifies neurotrophic signals required for fracture healing. | Xu M et al. | — | 2026 | → |
| Mechanistic insights into sodium citrate-induced metabolic rewiring for enhanced S-adenosylmethionine synthesis via transcriptomics and constraint-based modeling. | Dong L et al. | — | 2026 | → |
| Mechanosensor YAP orchestrates human neural rosette morphogenesis via TEAD4-LEF1 transcriptional nexus. | Hu J et al. | — | 2026 | → |
| Mesothelial cells promote peritoneal invasion and metastasis of ascites-derived ovarian cancer cells through spheroid formation. | Uno K et al. | — | 2026 | → |
| Metacycloprodigiosin from Rhizosphere <i>Streptomyces aurantiacus</i> as a Natural Antifungal Agent against <i>Fusarium oxysporum</i>. | Song L et al. | — | 2026 | → |
| Methaneseleninic acid, a circadian-modulating agent, reactivates latent HIV-1 infection without cellular activation or proliferation. | Stern J et al. | — | 2026 | → |
| Microbiota-mediated induction of beige adipocytes in response to dietary cues. | Tanoue T et al. | — | 2026 | → |
| Microglia protein profiles in CSF across Alzheimer's disease clinical stages. | Blujdea ER et al. | — | 2026 | → |
| Micropropagation of Cannabis sativa: genetic and epigenetic stability assessment over multiple generations. | Lefebvre V et al. | — | 2026 | → |
| miR-302 regulates pancreatic progenitor pool and pancreatic size. | Yang ZZ et al. | — | 2026 | → |
| Mitigating psychological stress-induced cardiac injury: The impact of CB2R agonists on endoplasmic reticulum stress and mitophagy. | Ma C et al. | — | 2026 | → |
| Mobile-CRISPRi as a tool for genetic manipulation in the intracellular pathogen <i>Piscirickettsia salmonis</i>. | Ortiz-Severin J et al. | — | 2026 | → |
| Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages. | Liu F et al. | — | 2026 | → |
| Modulation of the leaf transcriptome of Quercus robur by specialist and generalist herbivorous insects. | Mader M et al. | — | 2026 | → |
| Molecular mechanisms associated with rootstock-scion interactions in rubber trees. | Lima Cunha W et al. | — | 2026 | → |
| MRS2 and mitochondrial gene networks in endometrial cancer: mechanisms, biomarkers, and therapeutic implications. | Huang L et al. | — | 2026 | → |
| Mucosal DNA methylation reveals immune-related methylation profile and correlates with crohn's disease status. | Zhang T et al. | — | 2026 | → |
| Multidimensional profiling of heterogeneity in supratentorial ependymomas. | Jeong D et al. | — | 2026 | → |
| Multifaceted conserved functions of Notch during post-embryonic neurogenesis in the annelid Platynereis. | Bideau L et al. | — | 2026 | → |
| Multimodal data analysis reveals asynchronous aging dynamics across female reproductive organs. | Soldatkina O et al. | — | 2026 | → |
| Multiomic profiling of ER-positive HER2-negative breast cancer reveals markers associated with metastatic spread. | Mosquim Junior S et al. | — | 2026 | → |
| Multi-omics analysis of perfluorooctanoic acid and glioblastoma: insights from Mendelian randomization, network toxicology, and molecular docking. | Yang X et al. | — | 2026 | → |
| Multi-Omics Insights Into Anthraquinone Biosynthesis in Rheum tanguticum. | Zhao S et al. | — | 2026 | → |
| Multi-omics reveals co-regulation of hepatic bile acid metabolism in laying hens by host genetics and the cecal Anaerostipes. | Yang W et al. | — | 2026 | → |
| Multiorgan Molecular Landscape of Severe COVID-19 Revealed by Consensus Gene Signatures and RAB8B Targeting. | Avila JP et al. | — | 2026 | → |
| Multiorgan transcriptomics and circulating extracellular vesicle profiling reveal age-dependent systemic vulnerability to isoflurane anesthesia and surgery. | Krishnamachary B et al. | — | 2026 | → |
| Multispecies transcriptomics reveals influenza A virus modulation of <i>Streptococcus pneumoniae</i> EF3030 infection in human lung epithelium and murine lung. | D'Mello A et al. | — | 2026 | → |
| Multi-tissue transcriptomic aging atlas reveals predictive aging biomarkers in the killifish. | Costa EK et al. | — | 2026 | → |
| Mutational Landscape Analysis of BRCA1/2 and Identification of Extracellular-Vesicle-Related Biomarkers in Triple-Negative Breast Cancer. | Hu Y et al. | — | 2026 | → |
| Mutational signature-based classification uncovers emerging oral cancer subtypes with distinct molecular patterns. | Deneuve S et al. | — | 2026 | → |
| Myeloid-Derived CD38 Mediates Age-Related Endometrial Aging Through NAD<sup>+</sup> Depletion. | Hua L et al. | — | 2026 | → |
| NADPH oxidase-1 suppression prolongs the antidepressant-like effect of ketamine. | Nakajima W et al. | — | 2026 | → |
| Nasal organoids as optimal models for studying structure and function of primary nasal epithelial cell cultures. | Ramezanpour M et al. | — | 2026 | → |
| Native chromatome profiling reveals hundreds of metabolic enzymes in the nucleus across tissues. | Kourtis S et al. | — | 2026 | → |
| Natural variation in Arabidopsis uncouples leaf and flower development and reveals massive transcriptomic heterochrony. | Dieudonné S et al. | — | 2026 | → |
| Natural variation suggests candidate genes underlying Caenorhabditis elegans susceptibility to diverse toxicants. | Crombie TA et al. | — | 2026 | → |
| Neuroimmune dysregulation and comorbidity mechanisms of major depressive disorder and migraine. | Liang G et al. | — | 2026 | → |
| Neurometabolic rewiring in squid (Sepioteuthis lessoniana) optic lobes drives behavioral plasticity and visual integration under environmental acidification. | Allen GJP et al. | — | 2026 | → |
| Neuro-related gene signatures predict prognosis in diffuse large B-Cell lymphoma and uncover TRPV2-mediated tumor microenvironment regulation. | Su B et al. | — | 2026 | → |
| Neurotransmitter receptor-associated gene signature: prognostic and immunosuppressive microenvironment in NSCLC. | Yang Y et al. | — | 2026 | → |
| Newly Identified Transcriptomic Biomarkers and Gene Signature of Pathological Complete Response to Induction Chemoimmunotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma. | Zhou JG et al. | — | 2026 | → |
| Nicotinamide N-Methyl Transferase (NNMT) Sustains Innate Sensitivity to NAMPT Inhibition in YAP-dependent Stem-like/Mesenchymal Prostate Cancer. | Carreira ÁSA et al. | — | 2026 | → |
| NIK-driven IL-23 production by myeloid cells is a key factor in the development of autoimmune inflammation. | Ramphal NS et al. | — | 2026 | → |
| Nonhematopoietic MicroRNA-26b<sup>-/-</sup> Augments Atherosclerosis Development by Increasing Endothelial Inflammation and Leukocyte Adhesion-Brief Report. | Peters LJF et al. | — | 2026 | → |
| Non-invasive detection of bone marrow fibrosis in myeloproliferative neoplasms using cell-free RNA. | Saad M et al. | — | 2026 | → |
| Novel fatty acid metabolism-related molecular subtyping and prognostic signature for breast cancer. | Du J et al. | — | 2026 | → |
| Nuclear Receptors as Lethal Targets in the White-Backed Planthopper via RNAi and Nanocarrier Delivery. | Wang J et al. | — | 2026 | → |
| Optimising the induction of inflammation within preterm infant-derived intestinal epithelial organoids. | Chapman JA et al. | — | 2026 | → |
| Oral antigen exposure under costimulation blockade induces Treg cells to establish immune tolerance. | Arai M et al. | — | 2026 | → |
| Oral ginger-derived extracellular vesicles ameliorate arthritis via anti-inflammatory actions of microRNA-149 and 6-gingerol. | Kaneta H et al. | — | 2026 | → |
| Oxidative stress causes a reversible decrease of deubiquitylases activity in old vertebrate brains. | Sahu AK et al. | — | 2026 | → |
| p16<sup>Ink4a</sup>-Positive Hepatocytes Drive Liver Fibrosis Through Activation of LIFR Family Pathway. | Nishikawa K et al. | — | 2026 | → |
| p21-Positive Senescent Stromal Cells Promote Prostate Cancer Immune Suppression and Progression That Can Be Reversed by Senolytic Therapy. | Zhou L et al. | — | 2026 | → |
| p53 increases phospholipid headgroup scavenging in senescence. | Yashinskie JJ et al. | — | 2026 | → |
| Paneth cell SIRT1 deficiency increases intestinal stress resistance by modulating the gut microbiota. | Garcia-Peterson LM et al. | — | 2026 | → |
| Parathyroidectomy Restores Muscle Strength and Transcriptome in Individuals With Primary Hyperparathyroidism. | Björnsdotter-Öberg S et al. | — | 2026 | → |
| Pathogenomic analysis reveals clinically relevant epithelial-mesenchymal plasticity in esophageal squamous cell carcinoma. | Chen R et al. | — | 2026 | → |
| PCB 153 Modulates Genes Involved in Proteasome and Neurodegeneration-Related Pathways in Differentiated SH-SY5Y Cells: A Transcriptomic Study. | Minuti A et al. | — | 2026 | → |
| PCID2 is essential for spermatogonial differentiation by regulating alternative splicing. | Zhu F et al. | — | 2026 | → |
| Periostin contributes to differential sex-linked gene expression during infarct healing. | Abual'anaz BM et al. | — | 2026 | → |
| Photodynamic priming with Vitamin D and ALA-based PDT induces intratumoral immune cell recruitment and signaling pathway activation in cutaneous squamous cell carcinoma. | Shen AS et al. | — | 2026 | → |
| PIWIL1 activates the R2TP-TELO2-mTORC1 axis independently of piRNA to promote TOP mRNA translation in gastric cancer. | Fan T et al. | — | 2026 | → |
| Plasma Proteomic Profiling of Young and Older Adults Identifies Candidate Biomarkers of Biological Aging at the Intersection of Age and Disease. | Tavenier J et al. | — | 2026 | → |
| Polystyrene Nanoplastics at an Environmentally Relevant Concentration Promote Ovarian Cancer Progression via CDK4/6-Dependent Signaling. | Yuan X et al. | — | 2026 | → |
| Population and single-cell analyses reveal immune cell-specific expression profiles associated with Alzheimer's disease risk. | Lindbohm JV et al. | — | 2026 | → |
| Population differences in reproductive resource allocation and heterosis in the invasive vector Aedes albopictus. | Khorramnejad A et al. | — | 2026 | → |
| Potential of SERS and proteomics for biomarker detection in cancer cells. | Lilek D et al. | — | 2026 | → |
| Preterm Birth Increases Susceptibility to Hyperglycemia-Induced Kidney Injury With Sex-Specific Differences in Structural and Molecular Responses. | Dailey RK et al. | — | 2026 | → |
| Profiling of Extracellular Vesicles of Non-Small Cell Lung Cancer Reveals Proteins Associated With Osimertinib Resistance. | Cáceres-Verschae A et al. | — | 2026 | → |
| Prognostic gene screening and experimental validation in renal clear cell carcinoma based on spatial transcriptomics and single-cell sequencing. | Fu C et al. | — | 2026 | → |
| Prognostic Model Based on NAD+ Metabolism-Related Genes Predicts Breast Cancer Outcomes and Guides Immunotherapy. | Wang L et al. | — | 2026 | → |
| PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis. | Su T et al. | — | 2026 | → |
| Proteasome-guided haem signalling axis contributes to T cell exhaustion. | Xu Y et al. | — | 2026 | → |
| Protein networks are influenced by maternal BMI and differentiate preterm birth types. | Lopez Zapana PA et al. | — | 2026 | → |
| Protein tyrosine kinase Src suppresses hepatitis C virus particle release through regulation of Ndrg1. | Fu L et al. | — | 2026 | → |
| Proteome-Wide Analysis of Human Deletions. | Zhang H et al. | — | 2026 | → |
| Proteomic analysis reveals the pro-proliferative role of the LIN28B/HMGA2 axis in hepatoblastoma. | Shi J et al. | — | 2026 | → |
| Proteomic profiling of early-stage non-small cell lung cancer identifies a high-performance protein signature associated with postoperative recurrence. | Huang Y et al. | — | 2026 | → |
| Proteomic signatures and machine learning based-prediction models for cardiovascular risk in survivors of myocardial infarction. | Xiang S et al. | — | 2026 | → |
| ProteoNexus: an integrative database to characterize genetic architecture, estimate mediation effects, and construct and evaluate prediction models of the plasma proteome. | Shao K et al. | — | 2026 | → |
| Proximity extension assay-based serum proteomic profiling identifies shared protein signatures in hypermobile Ehlers-Danlos syndrome and hypermobility spectrum disorders. | Cinquina V et al. | — | 2026 | → |
| Proximity Labelling Reveals the Compartmental Proteome of Murine Sensory Neurons. | Sondermann JR et al. | — | 2026 | → |
| PRSS22 inhibits HMOX1-mediated ferroptosis and induces osteopontin cleavage to promote M2 macrophage polarization and colitis-associated carcinogenesis. | Kuang Z et al. | — | 2026 | → |
| PscOA: a plant scRNA-seq marker gene database for enhanced cellular transcriptome understanding. | Xu H et al. | — | 2026 | → |
| PTEN variant and genetic backgrounds combine to modify cerebellar neuronal differentiation in autism spectrum disorder. | Chen Y et al. | — | 2026 | → |
| PTUPB improves cognitive function in Alzheimer's disease associated with enhancing cerebral vascular myogenic response and attenuating vascular remodeling. | Morgan GC et al. | — | 2026 | → |
| Quantification and transcriptome profiling reveal abundant, dynamic and translatable dephospho-CoA-capped RNAs. | Hu H et al. | — | 2026 | → |
| QuickProt: A Fast and Accurate Homology-Based Protein Annotation Tool for Non-Model Organisms to Advance Comparative Genomics. | Chen G et al. | — | 2026 | → |
| RACGAP1 defines a malignant proliferative niche and represents a therapeutic vulnerability in lung adenocarcinoma. | Yi M et al. | — | 2026 | → |
| RAF-independent MEK mutations drive refractory histiocytic neoplasms but respond to ERK inhibition. | Diamond EL et al. | — | 2026 | → |
| RAPseq enables large-scale identification of RBP-RNA interactions and reveals essentials of post-transcriptional gene regulation. | Mosca R et al. | — | 2026 | → |
| Rare Cancer Explorer 1.0 (RaCE 1.0): a dedicated database and analytical platform focused on rare cancers. | Chen Y et al. | — | 2026 | → |
| Reciprocal regulation of fibroblast-macrophage equilibrium governs skin integrity. | Vollmers AC et al. | — | 2026 | → |
| Recombinant Expression and Antimicrobial Mechanism of Cysteine-Rich Antimicrobial Peptides from <i>Tigriopus japonicus</i> Genome. | Pu D et al. | — | 2026 | → |
| Recombinant spider silk membranes promote human renal epithelial differentiation and function. | Meyer A et al. | — | 2026 | → |
| Reduced Dietary Protein Induces Changes in the Dental Proteome. | Burroughs RW et al. | — | 2026 | → |
| Reduced fibre-fermenting capacity of gut microbes in multiple sclerosis may result in prebiotic dietary fibre β-fructan promoting inflammation and CNS damage. | Tollenaar SL et al. | — | 2026 | → |
| Reduced MGE burden, virulence optimization, and acid stress tolerance shape the clonal succession of MRSA ST59. | Jin Y et al. | — | 2026 | → |
| Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer. | Wang F et al. | — | 2026 | → |
| Regulon Reconstruction Uncovers Novel Deregulated Factors in Alzheimer's Disease. | Belém-Souza MV et al. | — | 2026 | → |
| Remodeling of homoeolog expression bias buffers stress response in allotetraploid cotton. | Cao J et al. | — | 2026 | → |
| Reprogramming offspring liver health: maternal indole supplementation as a preventive strategy against MASLD. | Mandala A et al. | — | 2026 | → |
| Reprogramming of stroma-derived chemokine networks drives the loss of tissue organization in nodal B cell lymphoma. | Czernilofsky F et al. | — | 2026 | → |
| Reprogramming the GRHL2-CDK19 axis by gene therapy alleviates prostate aging. | Sun G et al. | — | 2026 | → |
| Repurposing statins and phenothiazines to treat chemoresistant neuroblastoma. | Radke K et al. | — | 2026 | → |
| Resource Availability Modulates Gene Expression Across Life Stages in a Migratory Butterfly. | Shipilina D et al. | — | 2026 | → |
| Restoring the tumour mechanophenotype of vocal fold cancer reverts its malignant properties. | Kaivola J et al. | — | 2026 | → |
| RFLNA mitigates heat stress-impaired chondrocyte proliferation and vertebral development through cytoskeletal regulation in pigs. | Yang X et al. | — | 2026 | → |
| Rhapontigenin alleviates cellular senescence and physiological aging by upregulating sirt1 and promoting autophagy. | Liu S et al. | — | 2026 | → |
| RMzyme: regulations of RNA-modifying enzymes in humans. | Luo R et al. | — | 2026 | → |
| RNA N6-methyladenosine (m6A) regulates cell cycle progression in diffuse midline glioma (DMG) and confers sensitivity to FTO inhibition. | Ross SE et al. | — | 2026 | → |
| Role of MNX1-mediated histone modifications and PBX gene family in MNX1-induced leukemogenesis. | Malmhäll-Bah E et al. | — | 2026 | → |
| Roles of mitophagy and immune infiltration in Parkinson's disease: new perspectives from bioinformatics analysis and A53T transgenic mice. | Li X et al. | — | 2026 | → |
| Roles of THBS2<sup>+</sup> fibroblasts in malignant transformation of colorectal polyp to cancer. | Han Q et al. | — | 2026 | → |
| SASdb: a comprehensive database for sex-biased alternative splicing profiles in human tissues. | Chen X et al. | — | 2026 | → |
| SEA version 4.0: a major expansion and update of the Super-Enhancer Archive. | Shi B et al. | — | 2026 | → |
| Senescent-Like Myofibers Contribute to Anti-Regenerative Cytokine Signaling in Duchenne Muscular Dystrophy. | Ikeda M et al. | — | 2026 | → |
| Senolytic-Resistant Senescent Cells Have a Distinct SASP Profile and Functional Impact: The Path to Developing Senosensitizers. | Tripathi U et al. | — | 2026 | → |
| SETDB1 enables development beyond cleavage stages by extinguishing the MERVL-driven two-cell totipotency transcriptional program in the mouse embryo. | Zeng TB et al. | — | 2026 | → |
| Sex and life experience shape locus coeruleus pretangle tau pathology. | Hasan Z et al. | — | 2026 | → |
| Sex-specific hypothalamic PVN transcriptomic signatures of blood pressure autonomic regulation and neuroinflammation in hypertension. | Duque VJ et al. | — | 2026 | → |
| Shared Biomarkers LCN2 and CXCL11 for Ulcerative Colitis and Colon Cancer: Bioinformatics Analysis and Diagnostic Model Construction. | Wu Z et al. | — | 2026 | → |
| SiCmiR Atlas: Single-Cell miRNA Landscape Reveals Hub-miRNA and Network Signatures in Human Cancers. | Cai XX et al. | — | 2026 | → |
| Signal recognition particle-dependent secretome in humans. | Miller SC et al. | — | 2026 | → |
| Silencing RPL9 promotes malignant proliferation in breast cancer cells. | Zhu T et al. | — | 2026 | → |
| Single amino-acid differences define H2B variants and modify chromatin accessibility to induce EMT in breast cancer. | Dhahri H et al. | — | 2026 | → |
| Single Cell Analysis of Human Heart Failure With Preserved Ejection Fraction. | Hahn VS et al. | — | 2026 | → |
| Single-cell analysis reveals cytotoxic and memory CD8<sup>+</sup> T cells associated with prolonged survival in relapsed/refractory leukaemia patients after haplo+cord haematopoietic stem cell transplantation. | Li H et al. | — | 2026 | → |
| Single-cell analysis reveals neuroprotective histone deacetylase inhibitor pathways. | Peyton M et al. | — | 2026 | → |
| Single-Cell Analysis, Spatial Transcriptomics and Molecular Docking Unveil Potential Therapeutic Targets for Carotid Atherosclerosis. | Qin R et al. | — | 2026 | → |
| Single-cell and immune-context integration identifies basement-membrane/metastasis signatures that sharpen bladder-cancer diagnosis and prognosis. | Chen J et al. | — | 2026 | → |
| Single-cell and multi-omic characterization of ex vivo expanded ASTRLs from stable kidney transplant recipients reveals a regulatory T cell phenotype. | Tripathi S et al. | — | 2026 | → |
| Single-cell and multi-omics integrative modeling identifies mitochondrial gene HSPE1 as a therapeutic target in osteosarcoma. | Pan S et al. | — | 2026 | → |
| Single-cell atlas of AML reveals age-related gene regulatory networks in t(8;21) AML. | Whittle J et al. | — | 2026 | → |
| Single-cell atlas of the developing Down syndrome brain cortex. | Lattke M et al. | — | 2026 | → |
| Single-cell exon deletion profiling reveals splicing events that shape gene expression and cell state dynamics. | Kumari B et al. | — | 2026 | → |
| Single-cell omics and flow cytometry identify distinct immune states of dural and brain-infiltrating IL-17-producing γδ T cells after experimental stroke. | Zha M et al. | — | 2026 | → |
| Single-cell-resolved transcriptional dynamics of human subcutaneous adipose tissue during lifestyle- and bariatric surgery-induced weight loss. | Loft A et al. | — | 2026 | → |
| Single-cell RNA-seq reveals the piperlongumine is a potential drug for ischemic stroke. | Li J et al. | — | 2026 | → |
| Single-cell RNA sequencing elucidates potential mechanisms of endothelial cells in lung region-specific repair and remodeling in combined pulmonary fibrosis and emphysema. | Hu H et al. | — | 2026 | → |
| Single-cell RNA sequencing reveals disease associated changes in brain endothelial cells in the 5XFAD mouse. | Embalabala RJ et al. | — | 2026 | → |
| Single-cell RNA sequencing reveals transcriptional profiles of endometrial epithelial remodeling and identifies candidate genes regulating glandular cell development in Chinese Meishan pigs. | Jiang N et al. | — | 2026 | → |
| Single-Cell Transcriptomic Profiling Reveals That Macrophage-Induced Angiogenesis Contributes to Immunotherapy Resistance in Hepatocellular Carcinoma. | Pan X et al. | — | 2026 | → |
| Single-nucleus RNA sequencing reveals the distinct heterogeneity of primary pulmonary sarcomas (PPS) and pulmonary sarcomatoid carcinoma (PSC). | Zhu J et al. | — | 2026 | → |
| Single-nucleus transcriptomics of an engineered pig model reveals microglia-T cell interactions driving Huntington's disease neurodegeneration. | Li J et al. | — | 2026 | → |
| SIR-2.3/SIRT4 loss enhances proteostasis and neuronal resilience via AMPK-induced autophagy in Huntington's disease models. | Trujillo-Del Río C et al. | — | 2026 | → |
| Site-Specific and Quantitative O-GlcNAc Proteomics for Hepatocellular Carcinoma. | Hou C et al. | — | 2026 | → |
| Site-specific HPV18 integration facilitates cervical carcinogenesis through metabolic reprogramming-induced dysfunction of the SpHK1/S1P/S1PR1 pathway. | Wang L et al. | — | 2026 | → |
| SlERF-RD1 acts as a developmental coordinator integrating plant canopy architecture and the ethylene-mediated ripening cascade in tomato. | Aydoğdu S et al. | — | 2026 | → |
| SPAP: Soluble Human Plasma Proteoform Analysis via Acetonitrile Precipitation and Top-Down Mass Spectrometry. | Sanchez A et al. | — | 2026 | → |
| Spatial2GWAS: a database for linking spatial transcriptomic regions with GWAS traits. | Hu X et al. | — | 2026 | → |
| Spatial 5mC-seq profiling of embryos and decidua after implantation in mammals. | Shan X et al. | — | 2026 | → |
| Spatially-guided metabolomics profiling of metabolic regions in human tumor tissues. | Lee JJ et al. | — | 2026 | → |
| Spatially Resolved Proteomic Mapping in Skin Organoid for Hair Follicle Development. | Liang L et al. | — | 2026 | → |
| Spatial Transcriptomic Assessments of Gene Expression Profiles in Human Peri-Implant Lesions. | Dionigi C et al. | — | 2026 | → |
| Spatial transcriptomics reveals TGF-β-driven endothelial-mesenchymal transition in vascular remodeling of moyamoya disease. | Xiao J et al. | — | 2026 | → |
| Spatial transcriptomics uncovers lipid metabolic dysregulation driving immune-stroma crosstalk in Sjögren's Disease. | Li S et al. | — | 2026 | → |
| Splice modulation of COL4A5 reinstates collagen IV assembly in an organoid model of Alport syndrome. | Saei H et al. | — | 2026 | → |
| Spontaneous aging-associated inflammation and genome instability in the immune system of turquoise killifish. | Morabito G et al. | — | 2026 | → |
| SportsXbiodata: A web platform for integrative analysis of exercise-induced gene and protein expression. | Li Z et al. | — | 2026 | → |
| Stage-specific impacts of a simulated natural heatwave on Aedes albopictus. | Alfaro C et al. | — | 2026 | → |
| Stage-specific transcriptional atlas of goose satellite cells uncovers molecular dynamics driving embryonic skeletal muscle development. | Wang C et al. | — | 2026 | → |
| Stealth replication of SARS-CoV-2 Omicron in the nasal epithelium at physiological temperature. | Fonseca BF et al. | — | 2026 | → |
| Stem cell engineering for the generation of allogeneic CAR-directed natural killer T cells targeting endometrial carcinoma. | Li YR et al. | — | 2026 | → |
| Stress and light spectral quality influence the transcriptome of a tomato crop on the International Space Station. | Dixit AR et al. | — | 2026 | → |
| Structural, evolutionary and functional insights into the NAC gene family in Stevia rebaudiana and identification of important genes regulating steviol glycosides biosynthesis. | Sharma P et al. | — | 2026 | → |
| Study on biomarkers associated with epigenetic factors in endometriosis combining transcriptome with experimental validation. | Du J et al. | — | 2026 | → |
| Study on the expression level of folate receptor γ in thyroid cancer and its association with clinicopathological characteristics. | Cao J et al. | — | 2026 | → |
| Subtle-seq reveals frequent ageing-associated chromosome fragmentation on nucleosome core DNA. | Matsubara R et al. | — | 2026 | → |
| Sustained Transcriptional Response to Lipopolysaccharide and Interleukin-4 in an Immortalized Mouse Microglial Cell Line. | Herrero-González A et al. | — | 2026 | → |
| SyMetrics: an integrated machine learning model for evaluating the pathogenicity of synonymous variants in the human genome. | Bundalian L et al. | — | 2026 | → |
| Synchronizing the Liver Clock: Time-Restricted Feeding Aligns Rhythmic Gene Expression in Key Metabolic Pathways. | Liu S et al. | — | 2026 | → |
| Synergy between regulatory elements can render cohesin dispensable for distal enhancer function. | Hansen KL et al. | — | 2026 | → |
| Synovial transcriptome analysis reveals ShenTong ZhuYu Tang alleviates osteoarthritis by targeting MMP-9 and immune microenvironment. | Liang T et al. | — | 2026 | → |
| Syntaxin 4 protects islet β-cells from cytokine-induced senescence. | Ahn M et al. | — | 2026 | → |
| Systematic and Quantitative Investigation of Newly Synthesized Proteins Reveals Distinct Ion Homeostasis and Mitochondrial Changes between Cuproptosis and Ferroptosis in Human Cells. | Wu Y et al. | — | 2026 | → |
| Systematic Pathway Screening via Integrated Machine Learning Identifies FOXO-Mediated Transcription Signature for Robust Immunotherapy Response Prediction in Non-Small Cell Lung Cancer. | Wu S et al. | — | 2026 | → |
| Systematic post-translational modification genome wide identifies therapeutic targets for Alzheimer's disease: evidence from multi-cohort analysis. | Wang X et al. | — | 2026 | → |
| Targeting metabolic vulnerabilities: REV-ERB agonist SR9009 potentiates sorafenib efficacy in liver cancer. | Sabbioni S et al. | — | 2026 | → |
| Targeting the ERα DBD-LBD Interface with Mitoxantrone Disrupts Receptor Function through Proteasomal Degradation. | Wang H et al. | — | 2026 | → |
| TBL1X/TBL1XR1 govern β-cell identity through a PAX6-containing gene regulatory network. | Walth-Hummel AA et al. | — | 2026 | → |
| TEAD4 and RXRA Regulate the Function of Nucleus Pulposus Cells in Intervertebral Disc Degeneration Via the TNF-α/NF-κB Pathway: An Integrated Analysis of Single-Cell RNA-Seq, Bulk RNA-Seq, and In Vitro Validation. | Yang L et al. | — | 2026 | → |
| Telomere-to-telomere genome assembly of a male pig provides insight into population structure and selection for body stature. | Luo YB et al. | — | 2026 | → |
| TE-SCALE: a comprehensive database for exploring transposable element expression across human cancers at single-cell resolution. | Meng X et al. | — | 2026 | → |
| TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation. | Guo P et al. | — | 2026 | → |
| The Alzheimer's therapeutic Lecanemab attenuates Aβ pathology by inducing an amyloid-clearing program in microglia. | Albertini G et al. | — | 2026 | → |
| The auxin-CsHAT14 signaling cascade coordinates somatic embryogenesis in citrus. | Wang PB et al. | — | 2026 | → |
| The circ_0042103/TAF15/NER axis regulates inflammation and DNA damage in pulpitis. | Lai F et al. | — | 2026 | → |
| The critical role of <i>hcpR</i> in regulating nitrosative stress defense in <i>Clostridioides difficile</i>. | Kalra S et al. | — | 2026 | → |
| The cyclin dependent kinase (CDK)7 inhibitor BS-181 inhibits pathogenic Cryptococcus species, causing G<sub>2</sub>/M arrest and a splicing defect. | Sethiya P et al. | — | 2026 | → |
| The E-Protein Daughterless Regulates Olfactory Learning of Adult <i>Drosophila melanogaster</i>. | Tamberg L et al. | — | 2026 | → |
| The impact of rearing environment on C. elegans: phenotypic, transcriptomic and intergenerational responses to 3D enriched habitats. | Guisnet A et al. | — | 2026 | → |
| The innate thermogenic capacity of brown adipose tissue develops independently of sympathetic signaling. | Fein EC et al. | — | 2026 | → |
| The Molecular and Functional Landscape of Resistance to FOLFIRI Chemotherapy in Metastatic Colorectal Cancer. | Avolio M et al. | — | 2026 | → |
| The oleaginous yeast Cutaneotrichosporon oleaginosum modifies corn stover alkali lignin. | Gluth A et al. | — | 2026 | → |
| The PanOryza pangene catalog of Asian cultivated rice. | Contreras-Moreira B et al. | — | 2026 | → |
| The PbrMADS1-PbrMYB169 complex has uniquely emerged to regulate lignification of stone cells in pear. | Xue Y et al. | — | 2026 | → |
| Therapeutic targeting of BCL-2 during CART cell production augments potency through non-apoptotic adaptive changes. | Aboelella NS et al. | — | 2026 | → |
| theRNA: a curated knowledgebase of functional RNA therapeutics spanning diverse modalities and disease applications. | Zhou Y et al. | — | 2026 | → |
| The RNA-binding protein SRSF3 controls epicardial formation by regulating splicing and proliferation. | Lupu IE et al. | — | 2026 | → |
| The role of microRNAs in executive functions: a comprehensive review and bioinformatics analysis of human and animal studies. | Navarro-Flores A et al. | — | 2026 | → |
| The signature of pyroptosis-related gene diagnosis and immune microenvironment in preeclampsia. | Zhang J et al. | — | 2026 | → |
| The Tumor-to-Endothelial Transfer of FTO Promotes Vascular Remodeling and Metastasis in Nasopharyngeal Carcinoma. | Wu C et al. | — | 2026 | → |
| The ubiquitin ligase KLHL6 drives resistance to CD8<sup>+</sup> T cell dysfunction. | Cheng H et al. | — | 2026 | → |
| Thimerosal Inhibits Tumor Malignant Progression through Direct Action and Enhancing the Efficacy of PD-1-Based Immunotherapy. | Wang P et al. | — | 2026 | → |
| THO5 subunit of the Arabidopsis thaliana TREX complex: role in mRNA export and heat tolerance. | Ettner-Sitter A et al. | — | 2026 | → |
| Time-Resolved Oxidative Stress and Apoptosis in Murine Retina under Acute Hypobaric Hypoxia with Parallel Activation of the LIF-JAK-STAT3 Axis. | Wang H et al. | — | 2026 | → |
| Tissue integrity at the root of Metazoa - transcriptional landscape of whole-body regeneration in sponges. | Melnikov NP et al. | — | 2026 | → |
| TOX drives CD4<sup>+</sup> T<sub>H</sub>1 effector function, antitumor immunity and autoimmune pathology. | Naizir B et al. | — | 2026 | → |
| Transcriptome analysis of <i>Pantoea rara</i> mutants reveals the underlying complexity of bacterial phosphate solubilization. | Hone H et al. | — | 2026 | → |
| Transcriptome-metabolome integration reveals MYB/WRKY-RGA network and phenylalanine metabolism in potato late blight resistance. | Liu X et al. | — | 2026 | → |
| Transcriptome profiling reveals divergent response strategies in two olive cultivars with contrasting drought tolerance. | Martos de la Fuente GC et al. | — | 2026 | → |
| Transcriptomic insights into the immune dynamics of wild-type mice challenged with SARS-CoV-2 Beta variant. | Jahantigh HR et al. | — | 2026 | → |
| Transcriptomic insights into unisexual flower development in Cannabis sativa: conserved MADS-box networks and divergent developmental programs. | Lavie O et al. | — | 2026 | → |
| Transcriptomic prey-capture responses in convergently evolved carnivorous pitcher plants. | Wakatake T et al. | — | 2026 | → |
| Transcriptomics and metabolomics analysis reveal cell subpopulations of trophoblast cells associated with preeclampsia. | Zhu X et al. | — | 2026 | → |
| Transcriptomics-Guided Outcome Prediction (T-GOP) for Ecotoxicity Assessment: A Proof-of-Concept Study of PFOS Alternative OBS Disrupting Zebrafish Neurotransmitter Homeostasis and Cognition. | Zeng M et al. | — | 2026 | → |
| Transferrin receptor serves a role in promoting PANoptosis in thyroid cancer. | Ma S et al. | — | 2026 | → |
| Transgenerational effects of heat shock on gene regulation and fitness-related traits in natural Drosophila populations. | Harney E et al. | — | 2026 | → |
| TSC-associated microglial hyperactivity: enhanced calcium signaling, metabolism, and phagocytosis. | Kalf RS et al. | — | 2026 | → |
| Tumor-initiating stem cells fine-tune the plasticity of neutrophils to sculpt a protective niche. | Guo W et al. | — | 2026 | → |
| TUT1-catalyzed U6 snRNA 3'-end maturation is essential for RNA splicing and stem cell survival. | Fang Y et al. | — | 2026 | → |
| TWAS atlas 2.0: an updated data resource for transcriptome-wide association studies. | Gao H et al. | — | 2026 | → |
| Type I Interferon Pathway Activation Disrupts Monocyte Maturation and Enhances Immune Evasion in Multiple Myeloma. | Cui J et al. | — | 2026 | → |
| Uncovering the molecular logic of cortical wiring between neuronal subtypes across development through ligand-receptor inference. | Mathieu R et al. | — | 2026 | → |
| Unraveling Shared Diagnostic Biomarkers: Integrated Bioinformatics Identification of CGB7, MYCNUT, and GPR32 in Gestational Diabetes Mellitus and Retinopathy of Prematurity. | Liu L et al. | — | 2026 | → |
| Unraveling the Causal Linkages of <i>RBP7</i> and <i>SCGB3A1</i> on Pelvic Organ Prolapse: Multifaceted Insights From Genome-Wide Mendelian Randomization, Single-Cell RNA Analysis, and Network Pharmacology. | Yang Y et al. | — | 2026 | → |
| Unravelling the predominant genetic paths for asexual reproduction in Kalanchoe. | Meng XR et al. | — | 2026 | → |
| Unveiling the early defense response dynamics in grapevines against Plasmopara viticola by single-cell transcriptomics. | Yao X et al. | — | 2026 | → |
| Urinary Proteomics as a Noninvasive Readout of Obesity-associated Inflammation. | Canki E et al. | — | 2026 | → |
| Uterine natural killer cell-mediated immune imbalance impairs uterine vascular remodeling and contributes to adverse pregnancy outcomes in dengue virus-infected mice. | Xue F et al. | — | 2026 | → |
| Utilisation of Machine Learning Approaches Improves RNA-Seq Transcriptome Analyses in Alzheimer's Disease Brain. | Cheng Y et al. | — | 2026 | → |
| Vernalization regulatory network identifies potential novel functions for genes in the HvVRN2 locus. | Montardit-Tarda F et al. | — | 2026 | → |
| Vertical RAS pathway inhibition in pancreatic cancer drives therapeutically exploitable mitochondrial alterations. | Hafner P et al. | — | 2026 | → |
| Very high CO<sub>2</sub> concentrations inhibit photosynthesis and trigger transcriptomic stress responses in cyanobacteria. | Geissler AS et al. | — | 2026 | → |
| Welcome Pathogens: Transient Heat Dampens Immune Responses to Acibenzolar-S-Methyl in Apple Plants. | Chavonet E et al. | — | 2026 | → |
| Whole-Body Knockout of the AhR (Aryl Hydrocarbon Receptor) Ameliorates Atherosclerosis Due to Altered Lipid Metabolism-Brief Report. | Huchzermeier R et al. | — | 2026 | → |
| Whole genome analysis of toxic Papilionidae butterflies utilizing aristolochic acid, Pachliopta aristolochiae, and Byasa alcinous. | Komata S et al. | — | 2026 | → |
| Whole-grain black rice diet rewires the single-cell transcriptomic landscape of age-related ovarian decline in mice. | Tu YX et al. | — | 2026 | → |
| Whole-transcriptome identification of deleterious variants in candidate genes linked to bovine paratuberculosis. | Badia-Bringué G et al. | — | 2026 | → |
| YAP1 Enhances Mesenchymal-Type Gene Expression in Human Adrenergic-Type Neuroblastoma Cells. | Ludwig M et al. | — | 2026 | → |
| YKT6 Promotes Bladder Cancer Progression by Stabilizing β-catenin Through USP7-Mediated Deubiquitination. | Tu S et al. | — | 2026 | → |
| ZIC2 drives colorectal cancer progression by regulating QPRT-mediated cell migration. | Zheng L et al. | — | 2026 | → |
| 25-Hydroxycholesterol restricts human norovirus replication in human intestinal enteroids. | Costantini V et al. | — | 2025 | → |
| 3D chromatin-based variant-to-gene maps across 57 human cell types reveal the cellular and genetic architecture of autoimmune disease susceptibility. | Trang KB et al. | — | 2025 | → |
| 5-hydroxymethylcytosine signature in plasma extracellular vesicle DNA as a diagnostic molecular biomarker for precancerous lesions of gastric cancer. | Chen H et al. | — | 2025 | → |
| A 107 Gene Nanostring Assay Effectively Translates the Cancer Genome Atlas, and Tumour Microenvironment Gastric Cancer Molecular Classification to a Patient-Derived Organoid Model. | Skubleny D et al. | — | 2025 | → |
| A B cell-IgA-epithelial axis enhances antitumor immunity and improves outcome in HPV-associated penile squamous cell carcinoma. | Tao T et al. | — | 2025 | → |
| Aberrant adenosine A<sub>2A</sub> receptor signaling in the choroid plexus drives CSF hypersecretion and ventriculomegaly in hydrocephalus. | Zheng W et al. | — | 2025 | → |
| Aberrant alternative splicing in alcoholic hepatitis: regulatory roles of RBPs and sQTLs. | Zhao J et al. | — | 2025 | → |
| A chromosome-level genome assembly reveals triterpenoid biosynthesis in Clinopodium chinense. | Li G et al. | — | 2025 | → |
| A complete telomere-to-telomere assembly of Oryza sativa L. subsp. indica Kato T197 genome. | Zhang T et al. | — | 2025 | → |
| A core stemness-associated module reveals PLK1, NUF2, KIF23, CDCA8, TOP2A, CENPF, AURKA, and ASPM as key genes in rectal cancer. | Yao B et al. | — | 2025 | → |
| Activity dynamics and regulation mechanism of extracellular proteases in <i>Bacillus velezensis</i> SW5. | Feng X et al. | — | 2025 | → |
| Activity of the SWI/SNF complex is indispensable for syncytiotrophoblast formation. | Papuchova H et al. | — | 2025 | → |
| Addressing the mean-variance relationship in spatially resolved transcriptomics data with spoon. | Shah K et al. | — | 2025 | → |
| A diet-induced obese and diabetic host phenotype reduces mosquito ZIKV infections and remodels gut metabolism. | Menezes A et al. | — | 2025 | → |
| Adrenomedullin orchestrates treatment resistance in hepatocellular carcinoma via immune microenvironment remodeling. | Gao X et al. | — | 2025 | → |
| Adverse prognosis of GM-CSF expression in human cutaneous melanoma. | García-Martínez E et al. | — | 2025 | → |
| Age and anatomical site shape the gastrointestinal bacterial communities of captive American crocodiles (Crocodylus acutus). | López-Espinoza JU et al. | — | 2025 | → |
| Age-(in)dependent altered molecular mechanisms in Parkinson's disease through extracellular vesicle proteome and lipidome. | Zhang YT et al. | — | 2025 | → |
| Age-related aberrant alternative splicing as a prognostic tool in older breast cancer patients. | Chen M et al. | — | 2025 | → |
| Aging-associated transcriptional programs in T cells signify constituents of TGF-β signaling for immunosenescence. | He R et al. | — | 2025 | → |
| AI-Powered Structural and Co-Expression Analysis of Potato (<i>Solanum tuberosum</i>) <i>StABCG25</i> Transporters Under Drought: A Combined AlphaFold, WGCNA, and MD Approach. | Kurt B et al. | — | 2025 | → |
| Aire-dependent interferon signalling shapes thymocyte maturation and central tolerance in mice. | Jebrzycka A et al. | — | 2025 | → |
| ALCAM-CD6 axis suppression: a key determinant of immune-mediated metastasis recurrence in stage III non-small cell lung cancer. | Wen S et al. | — | 2025 | → |
| ALKBH1 Drives Tumorigenesis and Drug Resistance via tRNA-decoding Reprogramming and Codon-biased Translation. | Shen C et al. | — | 2025 | → |
| All-Trans Retinoic Acid Impacts Early Palatal Shelves Development via the Wnt and TGF-β Signaling Pathways. | Ma Y et al. | — | 2025 | → |
| Altered Co-Expression Patterns of Mitochondrial NADH-Dehydrogenase Genes in the Prefrontal Cortex of Rodent ADHD Models. | Sylko PA et al. | — | 2025 | → |
| A multi-layered regulatory model uncovers the central role of OsPRR37 in coordinating multiple agronomic traits. | Liu C et al. | — | 2025 | → |
| A multi-omics analysis of human fibroblasts overexpressing an Alu transposon reveals widespread disruptions in aging-associated pathways. | Bravo JI et al. | — | 2025 | → |
| Analysis of immune-related biomarkers in amniotic fluid embolism by sequencing data and bioinformatics. | Ma J et al. | — | 2025 | → |
| Angiogenesis-independent VEGF signaling enhances exercise capacity by increasing fat oxidation in mice fed sulfur amino acid-restricted diets. | Mann CG et al. | — | 2025 | → |
| An Integrated Multi-Omics Analysis Identifies Oxeiptosis-Related Biomarkers in Diabetic Retinopathy. | Deng J et al. | — | 2025 | → |
| ANKEF1 is a key axonemal component essential for murine sperm motility and male fertility. | Yu S et al. | — | 2025 | → |
| A novel alveoli-on-chip platform for modeling cyclic stretch in patient-derived alveolar epithelial cells cultured from organoids. | Hajari MA et al. | — | 2025 | → |
| A novel disulfidptosis-related lncRNAs index to predict prognosis and therapeutic target in hepatocellular carcinoma. | Gao XF et al. | — | 2025 | → |
| Anti-Cancer Activity of <i>Sphaerococcus coronopifolius</i> Algal Extract: Hopes and Fears of a Possible Alternative Treatment for Canine Mast Cell Tumor. | Mucignat G et al. | — | 2025 | → |
| Anti PD-L1 immunotherapy alters macrophage phenotypes via EGR1 and HSP90AB1 supported by integrated methodologies. | Shou X et al. | — | 2025 | → |
| Anti-progestin therapy targets hallmarks of breast cancer risk. | Simões BM et al. | — | 2025 | → |
| A predictive model for evaluating the risk of latent tuberculosis relapse via machine learning. | Wang C et al. | — | 2025 | → |
| A preserved TGFβ cytostatic response through DLD-mediated metabolic modulation undermines anti-TGFβ therapy in gastric cancer. | Pan YQ et al. | — | 2025 | → |
| A prognostic risk prediction model for gastric cancer based on the EFNA4 and ETS1 regulatory axis in tumor cells. | Chen Y et al. | — | 2025 | → |
| A Proteomic View of Butterfly Metamorphosis. | Hesketh A et al. | — | 2025 | → |
| A recent and rapid genome expansion driven by the amplification of transposable elements in the Neotropical annual killifish Garcialebias charrua. | Gajardo-Escobar F et al. | — | 2025 | → |
| A reference genome and transcriptome of haustorial development in <i>Pedicularis groenlandica</i> reveal diverse trajectories of haustoria-associated gene evolution in parasitic plants | Cohen RO et al. | — | 2025 | — |
| ASAH1-mediated sphingolipid metabolic reprogramming in venetoclax resistance of AML: beyond the monocytic phenotypes. | Zhao L et al. | — | 2025 | → |
| A single-cell atlas of the testicular interstitium defines Leydig progenitor networks sustaining Leydig cell homeostasis across the lifespan. | Huang X et al. | — | 2025 | → |
| Asparagine-related biomarkers and regulatory mechanisms in type 2 diabetes mellitus. | Xia J et al. | — | 2025 | → |
| ASPEN: Robust detection of allelic dynamics in single cell RNA-seq. | Petrova V et al. | — | 2025 | → |
| Association of blood-based DNA methylation of lncRNAs with Alzheimer's disease diagnosis. | Tian G et al. | — | 2025 | → |
| A systematic characterization of fibroblast subtypes and heterogeneity. | Zhu X et al. | — | 2025 | → |
| A transcriptomic atlas at bulk and single-cell levels identifies novel transcriptional and splicing regulators of ECM homeostasis in osteoarthritis. | Ye X et al. | — | 2025 | → |
| A unified single-cell atlas of human lung provides insights into pulmonary diseases. | Wu F et al. | — | 2025 | → |
| Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling. | Piletic K et al. | — | 2025 | → |
| Bacillus amyloliquefaciens orchestrates cell type-specific responses underlying drought tolerance in Arabidopsis. | Fan K et al. | — | 2025 | → |
| Bacterial communities co-develop with respiratory immunity early in life, linking dysbiosis to systemic monocyte signature and wheezing. | Pattaroni C et al. | — | 2025 | → |
| Bioinformatics and Experimental Validation of FLVCR1 and SOX4 in Regulating Mitochondria-Macrophage Crosstalk in Disc Degeneration. | Zhou J et al. | — | 2025 | → |
| Bioinformatics-based multi-omics and machine learning analysis identifies stemness-associated molecular subtypes and a prognostic index in breast cancer. | Hou YY et al. | — | 2025 | → |
| Bioinformatics-based screening and experimental validation of biomarkers for the treatment of connective tissue-associated interstitial lung disease with liquorice and dried ginger soup. | Yuan H et al. | — | 2025 | → |
| Bioinformatics identification of key genes correlating NOD1 and Endoplasmic Reticulum stress in Hepatitis B virus-induced acute liver failure. | Deng F et al. | — | 2025 | → |
| Biomarker-Based Precision Prediction of Immunotherapy Response in Hepatocellular Carcinoma. | Chao HW et al. | — | 2025 | → |
| BloodCircR: A comprehensive database for human peripheral blood circular RNAs. | Yuan S et al. | — | 2025 | → |
| BNC2 as a novel driver of pancreatic cancer progression through transcriptional regulation of COL3A1 and epithelial-to-mesenchymal transition. | Li X et al. | — | 2025 | → |
| BNIP3 is a key driver of breast cancer progression and a novel glycolysis-regulating biomarker. | Cao L et al. | — | 2025 | → |
| Brain-derived neurotrophic factor supports pericyte and vascular homeostasis in the aging brain. | Luo Q et al. | — | 2025 | → |
| Bridging metabolism and immuno-inflammation: a novel framework to characterize dilated cardiomyopathy subtype. | Yu C et al. | — | 2025 | → |
| BT-11 targets the LANCL2 pathway to attenuate cognitive deficits and hippocampal pathology in Alzheimer's transgenic rats. | Birnbaum EM et al. | — | 2025 | → |
| Bulk and single-cell transcriptome analysis reveal shared key genes and patterns of immune dysregulation in systemic lupus erythematosus and sepsis. | Wen X et al. | — | 2025 | → |
| Bulk RNA Sequencing Reveals Signature Differences in Key Cell Signaling Pathways Between Porcine Venous and Arterial Smooth Muscle Cells. | Lee KA et al. | — | 2025 | → |
| Cationic amino acid transporters (CAT) enhance accumulation and susceptibility to the systemic herbicide L-phosphinothricin. | Tan GZH et al. | — | 2025 | → |
| Cationic Antimicrobial Copolymers Reveal Immunomodulatory Properties in Lipopolysaccharide Stimulated Macrophages <i>in Vitro</i>. | Laroque S et al. | — | 2025 | → |
| CDK7 is a novel therapeutic target in fibrolamellar carcinoma. | Nukaya M et al. | — | 2025 | → |
| CELF1 promotes aerobic glycolysis and an aggressive phenotype in ER-positive breast cancer via GLUT1 regulation. | Li J et al. | — | 2025 | → |
| Cellular and Extracellular MicroRNA Dysregulation in LRRK2-Linked Parkinson's Disease. | Knab F et al. | — | 2025 | → |
| Cellular and genetic mechanisms that shape the development and evolution of tail vertebral proportion in mice and jerboas. | Weber CJ et al. | — | 2025 | → |
| Cellular and molecular mechanisms of seahorse male pregnancy. | Liu Y et al. | — | 2025 | → |
| Cerebrospinal Fluid From Patients With HTLV-1-associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) With Rapid Evolution Affects Mitochondrial DNA Transcription and Network Organization in Human Glioblastoma Cells. | Gomes YCP et al. | — | 2025 | → |
| Cerebrospinal fluid proteomic signatures in cognitively normal individuals identify distinct clusters linked to neurodegeneration. | Seo D et al. | — | 2025 | → |
| Characterization of pancreatic cancer stem cells and construction of a stem cell-based prognostic signature. | Fang J et al. | — | 2025 | → |
| Characterization of PANoptosis-related expression pattern, prognosis and tumor microenvironment in head and neck squamous cell carcinoma. | Zhang M et al. | — | 2025 | → |
| Chemotherapy-driven intestinal dysbiosis and indole-3-propionic acid rewire myelopoiesis to promote a metastasis-refractory state. | Bersier L et al. | — | 2025 | → |
| Chromatin activity of IκBα mediates the exit from naïve pluripotency. | Palma LG et al. | — | 2025 | → |
| Chromosome-level genome assembly of trypanosomatid parasite Lotmaria passim links chromosome duplication and divergence with infection of honey bees. | Nearman A et al. | — | 2025 | → |
| Chromosome-scale assemblies of flowering dogwood cultivars enable identification of candidate genes regulating anthocyanin biosynthesis in leaves and bracts. | Hamm TP et al. | — | 2025 | → |
| Circular RNAs in diabetes mellitus and its complications: a systematic review and in silico analyses. | Dieter C et al. | — | 2025 | → |
| Clinical Impact of Immunoglobulin Heavy Chain Clonality in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia. | Katai Y et al. | — | 2025 | → |
| Closing the evidence loop-membrane-lipid homeostasis and vesicular transport link DEHP exposure to endometriosis. | Dai Y et al. | — | 2025 | → |
| Combined Vacuum and Ascorbic Acid Treatment Enhances Texture and Antioxidant Capacity in Fresh-Cut Potatoes: Transcriptomic Elucidation of Glutathione Metabolism Mechanisms. | Fang R et al. | — | 2025 | → |
| Combining AlphaFold-based AI docking with omics technologies preliminarily unveils the mechanism of Guominkang in treating allergic rhinitis. | Zhou Y et al. | — | 2025 | → |
| Comparative genomic and clinicopathological analysis uncovers contrasting molecular profiles of canine and human thyroid carcinomas. | Das S et al. | — | 2025 | → |
| Comparative histomorphometric and transcriptomic analysis reveals potential genetic determinants of pelage variation between hairy and coarse-woolly sheep. | Liang Q et al. | — | 2025 | → |
| Comparative Muscle Quality and Multiomic Analyses in Wild-Type and Yellow-Mutant <i>Triplophysa siluroides</i>: TGF-β/BMP-Mediated Covariation and Breeding for Muscle Quality. | Ni L et al. | — | 2025 | → |
| Comparative Proteomic Analysis of <i>Acremonium chrysogenum</i> Strains: Key Changes Converting the Wild-Type Strain into Antibiotic Cephalosporin C Biofactory. | Zhgun AA et al. | — | 2025 | → |
| Comparative transcriptomic analysis of perfluoroalkyl substances-induced responses of exponential and stationary phase Escherichia coli. | Wintenberg ME et al. | — | 2025 | → |
| Complement pathway dysregulation and astrocyte alterations in Down syndrome: evidence from postmortem brain tissue and iPSC-derived astrocytes. | Teles E Silva AL et al. | — | 2025 | → |
| Complement system activation in wild boar (<i>Sus scrofa</i>) following parenteral administration of heat-inactivated <i>Mycobacterium bovis</i>. | Villar M et al. | — | 2025 | → |
| Comprehensive analysis of genes associated with necroptosis and pyroptosis in intestinal ischemia-reperfusion injury. | Bao S et al. | — | 2025 | → |
| Comprehensive analysis of molecular epidemiological characteristics of <i>Morganella intermedius</i>: a novel genospecies of <i>Morganella morganii</i> frequently isolated from environmental sources. | Chen J et al. | — | 2025 | → |
| Comprehensive Analysis Reveals Biomarkers Related to Diabetic Peripheral Neuropathy and Its Molecular Mechanism. | Zhu Q et al. | — | 2025 | → |
| Comprehensive bulk and single-cell RNA sequencing uncovers senescence-associated biomarkers in therapeutic mesenchymal stem cells. | Pekker E et al. | — | 2025 | → |
| Comprehensive map of the regulatory network triggered by MET exon 14 skipping reveals important involvement of the RAS-ERK signaling pathway. | Truong MJ et al. | — | 2025 | → |
| Comprehensive Proteomics Profiling Reveals Biomarkers of Oxidative Stress and Membrane Integrity in Red Blood Cells in Acute Altitude Sickness. | Li S et al. | — | 2025 | → |
| Computational decoding of cell-cycle phase effects on cancer hallmarks across breast cancer subtypes. | Castresana-Aguirre M et al. | — | 2025 | → |
| Computational prediction of cellular elastic modulus from mechanosensitive gene expression at multiple biological levels. | Xiong Y et al. | — | 2025 | → |
| Concurrent PIK3CA mutant promotes cachexia through inflammatory signaling in EGFR mutant lung cancer. | Yue M et al. | — | 2025 | → |
| Constructing a Prognostic Model for Clear Cell Renal Cell Carcinoma Based on Glycosyltransferase Gene and Verification of Key Gene Identification. | Zhou C et al. | — | 2025 | → |
| Construction and identification of a prognostic and therapeutic signature based on ferroptosis-related oxidative stress genes in lung adenocarcinoma. | Yao D et al. | — | 2025 | → |
| Construction and validation of a transmembrane 4 superfamily-related genes prognostic model for esophageal squamous cell carcinoma. | Hao X et al. | — | 2025 | → |
| Construction and validation of risk models of prognostic genes associated with parthanatos in papillary thyroid carcinoma based on bioinformatics. | Wang R et al. | — | 2025 | → |
| Construction and verification of a prognostic model for prostate cancer based on ribosome biogenesis-related genes. | Xie J et al. | — | 2025 | → |
| Continuous cell-type diversification in mouse visual cortex development. | Gao Y et al. | — | 2025 | → |
| Convergent subgenome dominance but with lineage-specific functional divergence of homoeologs during cave adaptation: insights from full-length transcriptomes of Sinocyclocheilus species. | Xu S et al. | — | 2025 | → |
| CRISPR/Cas9-Mediated <i>pds</i> Knockout in Potato Reveals Network-Level Transcriptomic Reorganization Beyond Pigment Loss. | Lai X et al. | — | 2025 | → |
| Cross-Disease Identification of FBP1 in Atherosclerosis and Calcific Aortic Valve Disease via Integrated Bioinformatics and Validation: Functional Analysis and Therapeutic Target Exploration. | Xu H et al. | — | 2025 | → |
| Cross Disease Single-Cell Meta-Analysis Deciphers Conserved Pan-Inflammatory Circuits and Divergent Endothelial Rewiring in Inflammatory Skin Pathogenesis. | Xu J et al. | — | 2025 | → |
| Cross-Study Meta-Analysis of Blood Transcriptomes in Type 2 Diabetes. | Tkachenko AA et al. | — | 2025 | → |
| Cross-tissue enrichment patterns reveal functional clustering in normal human tissues from GTEx. | P S A et al. | — | 2025 | → |
| CT-based intratumoral heterogeneity quantification fusing deep learning radiomics for predicting lymph node metastasis in early-stage lung adenocarcinoma: a multicenter study. | Hu M et al. | — | 2025 | → |
| CYP27A1 suppresses brain metastasis via ferroptosis in lung adenocarcinoma: a six-gene signature predicting the immunotherapy response and clinical outcomes. | Xu L et al. | — | 2025 | → |
| Cytochrome c oxidase dependent respiration is essential for T cell activation, proliferation and memory formation. | Tarasenko TN et al. | — | 2025 | → |
| Decoding epithelial-T cell interactions in colorectal cancer through single-cell and spatial transcriptomics. | Yu R et al. | — | 2025 | → |
| Decoding Potential Cuproptosis-Related Genes in Sarcopenia: A Multi-Omics Network Analysis. | Yan H et al. | — | 2025 | → |
| Decoding protein N-phosphorylation functionality and sequence patterns. | Zhao MX et al. | — | 2025 | → |
| Decoding the peripheral transcriptomic and meta-genomic response to music in autism spectrum disorder via saliva-based RNA sequencing. | Cavenaghi A et al. | — | 2025 | → |
| Decoding the Prognosis-Related S100A9<sup>high</sup> Monocyte in Glioblastoma Using Single-Cell and Spatial Transcriptome Sequencing. | Li X et al. | — | 2025 | → |
| Deep immune profiling delineates hallmarks of disease heterogeneity in extrapulmonary tuberculosis. | Theobald SJ et al. | — | 2025 | → |
| Deletion of the X-chromosomal gene <i>Kdm6a</i> in microglia of female mice ameliorates neuroinflammation and restores translatome profiles. | Itoh Y et al. | — | 2025 | → |
| Denoising single-cell RNA-seq data with a deep learning-embedded statistical framework. | Luo Q et al. | — | 2025 | → |
| Deriving consensus sepsis clusters via goal-directed subgroup identification in multi-omics study. | Zhang Z et al. | — | 2025 | → |
| Development and application of a barcoded rabies viral tracing method for mapping brain-wide inputs to single neurons. | Tan K et al. | — | 2025 | → |
| Development and validation of a prognostic prediction model for gastric cancer based on lipophagy-related genes. | Wusiman L et al. | — | 2025 | → |
| Development and verification of lymphangiogenesis score for prediction of prognosis and immune landscape in gastric cancer. | Liu S et al. | — | 2025 | → |
| Development of a prognostic model related to mitochondria and programmed cell death-related genes in bladder cancer. | Zhao X et al. | — | 2025 | → |
| Diel expression dynamics in filamentous cyanobacteria. | Kennedy SJ et al. | — | 2025 | → |
| Dietary methionine deprivation enhances renal resilience against ischemia-reperfusion injury in mice through modulation of glucose oxidation. | Peng X et al. | — | 2025 | → |
| Dietary restriction-responsive genes define prognostic subtypes and predict metastasis in colorectal cancer. | Li Q et al. | — | 2025 | → |
| Diet modulates Vibrio cholerae colonization and competitive outcomes with the gut microbiota. | Liu R et al. | — | 2025 | → |
| Differential DNA methylation and gene expression in stem cell-derived cardiomyocytes from patients with and without a history of clozapine-induced myocarditis. | Marques D et al. | — | 2025 | → |
| Differential expression of platelet CD147 in moderate altitude conditions: implications for coronary plaque stability assessment. | Chen Y et al. | — | 2025 | → |
| Disparate leukemia mutations converge on nuclear phase-separated condensates. | Datar GK et al. | — | 2025 | → |
| Disrupted genes and pathways in schizophrenia: a robust analysis of the brain and blood. | Rebouças R et al. | — | 2025 | → |
| Dissecting regulatory non-coding GWAS loci reveals fibroblast causal genes with pathophysiological relevance to heart failure. | Gill R et al. | — | 2025 | → |
| Dissecting two contrasting phytoplankton-symbiont interaction modes based on population dynamics and gene expression patterns. | Yang JW et al. | — | 2025 | → |
| Distinct Effects of Biological Treatments on Eosinophils and Neutrophils in Chronic Rhinosinusitis With Nasal Polyp Patients. | Van Nevel S et al. | — | 2025 | → |
| Distinct miRNA profiles in human amniotic tissue and its vesicular and non-vesicular secretome. | Chaves-Solano N et al. | — | 2025 | → |
| D-lactic acid inhibits Candida albicans associated with vulvovaginal candidiasis: in vitro and in vivo effects and underlying mechanisms. | Xia T et al. | — | 2025 | → |
| DNA/RNA hybrid profiling in autistic patients: A focus on mRNA and non-coding RNA variations. | Kianmehr L et al. | — | 2025 | → |
| Dynamic screening initiation using 16 plasma protein biomarkers with polygenic risk and PLCOm2012: a precision prevention framework for lung cancer. | Wang R et al. | — | 2025 | → |
| Dysfunction and Pathological Origins of Lymphatic Endothelial Cells in Atherosclerosis Revealed by Single-Cell Transcriptomics. | Shen Q et al. | — | 2025 | → |
| Dysregulated circRNA-miRNA-mRNA networks reveal stage-specific mRNA expression changes in Parkinson's disease. | Gao Y et al. | — | 2025 | → |
| Early alternative splicing signatures and RBP networks in MASLD progression to cirrhosis. | Chen L et al. | — | 2025 | → |
| Effect of creep-feeding supplementation during the pre-weaning phase on gene co-expression in Longissimus thoracis muscle of F1 Angus x Nellore calves at weaning. | Reolon HG et al. | — | 2025 | → |
| Effects of Methylcobalamin on Mitochondrial Alterations in Schwann Cells Under Oxidative Stress. | Li Q et al. | — | 2025 | → |
| Efferocytosis-associated genes serve as prognostic biomarkers for pancreatic ductal adenocarcinoma and identify P2RY6 as a therapeutic target. | Wang X et al. | — | 2025 | → |
| Elevated SLC1A5 links to inflamed endothelial cells and proteinuria in membranous nephropathy patients. | Tang Q et al. | — | 2025 | → |
| Elovl7 sensitizes podocytes to ferroptosis in podocytopathy by elongating polyunsaturated fatty acids. | Kang M et al. | — | 2025 | → |
| Elucidating Pancreatic Ductal Adenocarcinoma Carcinogenesis at Single-Cell Resolution and Identifying Subtype Specific Drug Candidates. | Chen J et al. | — | 2025 | → |
| Emerging roles of basophils in the resolution of acute respiratory distress syndrome. | Takasawa S et al. | — | 2025 | → |
| Ensemble model for neoadjuvant chemotherapy response prediction and treatment sensitivity in TNBC based on DNA replication stress signatures. | Hu M et al. | — | 2025 | → |
| Environmental Microbial Cues Alter Embryonic Development and Stress Responses in Vertebrates: Insights From the Zebrafish (Danio rerio) Model. | Green EM et al. | — | 2025 | → |
| Eosinophil extracellular traps formation is correlated with cancer prognosis by tumor microenvironment remodeling. | Zhang J et al. | — | 2025 | → |
| Epithelial AhR Suppresses Allergen-Induced Oxidative Stress and Senescence via c-Myc Regulation. | Chen Z et al. | — | 2025 | → |
| Establishment and validation of a prognostic risk model based on ADME-related genes in breast cancer. | Yang Y et al. | — | 2025 | → |
| Establishment of novel cholangiocarcinoma cell lines with ARID1A deficiency and preclinical validation of synthetic lethality therapies. | Prasopporn S et al. | — | 2025 | → |
| Establishment of prognostic signature based on neutrophil extracellular traps-related genes in acute myeloid leukemia: a bioinformatics analysis. | Shen Z et al. | — | 2025 | → |
| Exosomal microRNA-20b-5p contributes to cytarabine resistance in acute myeloid leukemia via the microtubule-associated serine/threonine kinase-like-phosphatidylinositol 3-kinase-protein kinase B signaling axis. | Huang A et al. | — | 2025 | → |
| Exploring Functionally Enhanced BLP-Trained Macrophage Subpopulations in S. Aureus Infection: Underlying Mechanisms and Therapeutic Significance. | Wan Y et al. | — | 2025 | → |
| Exploring hypoxia- and cuproptosis-related biomarkers in periodontitis based on transcriptome and single-cell analysis. | Zheng Y et al. | — | 2025 | → |
| Exploring the impact of endocrine-disrupting chemicals on erectile dysfunction through network toxicology and machine learning. | Liu Z et al. | — | 2025 | → |
| Exploring the link between osteoporosis and stroke risk: An exploratory study based on 2017-2018 NHANES clinical data and bioinformatics analysis. | Ren W et al. | — | 2025 | → |
| Exploring the Mechanism of Nicotine on Human Chronic Wounds Based on Network Toxicology and Molecular Docking. | Guo G et al. | — | 2025 | → |
| Exploring the pathogenesis of steroid-induced osteonecrosis of the femoral head co-regulated by mesenchymal stem cells and pyroptosis-related genes with the use of transcriptome. | Rong XB et al. | — | 2025 | → |
| Exploring the prognostic value of T cell exhaustion and mitochondrial dysfunction related genes in breast cancer through bioinformatics analysis and RT-qPCR validation. | Wan H et al. | — | 2025 | → |
| Exploring the role of lipid metabolism genes in gastric cancer prognosis and tumor immune microenvironment. | Xiao Y et al. | — | 2025 | → |
| Expression of long noncoding RNAs in peripheral blood mononuclear cells of patients with type 1 diabetes mellitus: potential biomarkers for disease onset. | Dieter C et al. | — | 2025 | → |
| Expression patterns and clinical implications of chaperonin subunit 3 mRNA and protein in laryngeal squamous cell carcinoma. | Mo BY et al. | — | 2025 | → |
| Extracellular vesicle miR-425-5p promotes visceral fat reduction via DACT1 suppression in SGLT2i-treated diabetes. | Park JH et al. | — | 2025 | → |
| Extracellular vesicles derived from pro-inflammatory M1 macrophages induce an inflammatory and invasive phenotype in melanoma cells. | Mäki-Mantila K et al. | — | 2025 | → |
| Extracellular Vesicles From Multiple Sclerosis White Matter Exhibit Synaptic, Mitochondrial, Complement and Ageing-Related Pathway Dysregulation. | Jank L et al. | — | 2025 | → |
| Ex vivo lung-organoid model for aberrant basaloid cell induction and activation. | Wu B et al. | — | 2025 | → |
| Ferritinophagy-related prognostic genes UBE2Q1, NEDD4L, and TCP11L2 for prognosis prediction in sepsis. | Xiong W et al. | — | 2025 | → |
| Ferroptosis-induced remodeling of glycosylation the immune microenvironment and improves survival in pancreatic cancer. | Tan H et al. | — | 2025 | → |
| Functional characterization of a bovine luteal cell culture model: Effects of passage number. | Sharma A et al. | — | 2025 | → |
| Functional insight into cyclin-dependent kinase (CDK)7 via chemical inhibition of the priority fungal pathogen <i>Cryptococcus neoformans</i>. | Sethiya P et al. | — | 2025 | → |
| Functional S-persulfidation exploration reveals a novel regulatory mechanism of HNF1α. | Huang Y et al. | — | 2025 | → |
| FX-Cell: a method for single-cell RNA sequencing on difficult-to-digest and cryopreserved plant samples. | Ming X et al. | — | 2025 | → |
| Galactin-3 regulation of CDC42 promotes neuronal autophagy following spinal cord injury. | Yan L et al. | — | 2025 | → |
| Gap-Free T2T assemblies of Micropterus salmoides identify a Y-Linked SV hotspot underlying sexual dimorphism. | Liu S et al. | — | 2025 | → |
| GeDi: simplifying gene set distances for enhanced omics interpretation in R/Bioconductor. | Nedwed AS et al. | — | 2025 | → |
| Gemcitabine-cisplatin chemotherapy plus anti-PD-L1 therapy reinvigorates antitumor immune response by reprogramming the intrahepatic cholangiocarcinoma microenvironment. | Song Y et al. | — | 2025 | → |
| Gene Profiling Analyses of Synovium Tissues in Korean Osteoarthritis Patients. | Roh J et al. | — | 2025 | → |
| Gene regulatory dynamics during craniofacial development in a carnivorous marsupial. | Cook LE et al. | — | 2025 | → |
| Genetic basis of flavor complexity in sweet corn. | Li K et al. | — | 2025 | → |
| Genome- and transcriptome-wide association meta-analysis reveals new insights into genes affecting coronary and peripheral artery disease. | Rode M et al. | — | 2025 | → |
| Genome sequencing provides novel insights into diadromous migration adaptations in the roughskin sculpin, <i>Trachidermus fasciatus</i> (Scorpaeniformes, Cottidae). | Liu T et al. | — | 2025 | → |
| Genome-wide association study reveals candidate genes for litter size and function validation of <i>MMP16</i> gene in lop sheep. | Wang J et al. | — | 2025 | → |
| Genome-wide CRISPR screen reveals an uncharacterized spliceosome regulator as new candidate immunotherapy target. | Shao T et al. | — | 2025 | → |
| Genome-wide identification of heat shock factors in Myricaria laxiflora and their response to abiotic stresses. | Li L et al. | — | 2025 | → |
| Genome-wide identification of the Remorin genes in Adiantum nelumboides and their responses to diverse abiotic stresses. | Li L et al. | — | 2025 | → |
| Genome-wide selection analysis identifies genes associated with mandibular defects in Duolang sheep. | Cao H et al. | — | 2025 | → |
| Genomic data-driven framework for drug target discovery in atrial fibrillation. | Tao Y et al. | — | 2025 | → |
| Global DNA methylation signatures associated with chemoresistance and poor prognosis of high grade serous ovarian cancer. | Manzoor HB et al. | — | 2025 | → |
| Glutamine metabolism reprogramming promotes bladder cancer progression via PYCR1: a multi-omics and functional validation study. | Ding X et al. | — | 2025 | → |
| GRB10 as a pan-cancer biomarker linking oncogenic signaling, immunosuppression, and immunotherapy resistance. | Guo H et al. | — | 2025 | → |
| Harnessing machine learning for the development, validation, and prognostic evaluation of MASHRisk score: insights from a multicohort study. | Ye B et al. | — | 2025 | → |
| HAUS6 as a potential prognostic and immunological biomarker: validation from pan-cancer analysis to hepatocellular carcinoma. | Xie H et al. | — | 2025 | → |
| Hepatitis B virus is a stealth virus that minimizes proteomic and secretomic changes in primary human hepatocytes. | Štaflová K et al. | — | 2025 | → |
| Heterogeneity in an adeno-associated virus transfection-based production process limits the production efficiency. | Ladd B et al. | — | 2025 | → |
| High interferon response signatures in SLE patient leukocytes are associated with increased transposable element expression in gene introns and intergenic regions. | Arteaga-Vazquez LJ et al. | — | 2025 | → |
| High-sensitivity plasma proteomics reveals disease-specific signatures and predictive biomarkers of Alzheimer's disease phenotypes in a large mixed-dementia cohort. | Gong K et al. | — | 2025 | → |
| Histone acetyltransferase 1 promotes postinfarction inflammatory response by regulation of monocyte histone succinylation. | Guo Y et al. | — | 2025 | → |
| HLA-A drives diabetic retinopathy pathogenesis: multi-omics integration reveals resveratrol's therapeutic potential via immunomodulation. | Lin J et al. | — | 2025 | → |
| HMMR mediates progression of nasopharyngeal carcinoma by inhibiting FAM83D ubiquitination and activating beta-catenin signaling pathway. | Zhong F et al. | — | 2025 | → |
| Hmox1 expression indicates distinct injury phenotypes of proximal tubule cells in sepsis-associated acute kidney injury. | He Y et al. | — | 2025 | → |
| Host-specific bacterial modulation of airway gene expression and alternative splicing. | Horvath M et al. | — | 2025 | → |
| Housing environment bilaterally alters transcriptomic profile in the rat hippocampal CA1 region. | Kubota A et al. | — | 2025 | → |
| HOXC10 Protects from Skin Aging by Targeting the FZD6/Wnt/β-Catenin Signaling Pathway. | Zhong Y et al. | — | 2025 | → |
| HPCAL1 as a novel prognostic biomarker in acute myeloid leukemia and its correlation with immune infiltrates. | Cheng L et al. | — | 2025 | → |
| HUBMet: an integrative database and analytical platform for human blood metabolites and metabolite-protein associations. | Wang X et al. | — | 2025 | → |
| Human colon stem cells are the predominant epithelial responders to bacterial antigens. | De Vries MH et al. | — | 2025 | → |
| Hydrogel-Wrapped <i>Calendula officinalis</i> L. extracellular vesicles - A novel approach to enhance fracture healing by Macrophage reprogramming. | Wang X et al. | — | 2025 | → |
| Hyperactive 20<i>S</i> proteasome enhances proteostasis and ERAD in <i>C. elegans</i> via degradation of intrinsically disordered proteins. | Salcedo-Tacuma D et al. | — | 2025 | → |
| Hyperspectral imaging of grains uncovers the genetic architecture of nitrogen response of development in bread wheat. | Liu Q et al. | — | 2025 | → |
| Hypo-glycosylated FSH enhances the ovarian microenvironment for follicular development compared to fully glycosylated FSH. | Tang J et al. | — | 2025 | → |
| Identification and experimental validation of biomarkers associated with macrophages in myocardial ischemia-reperfusion injury. | Jiang X et al. | — | 2025 | → |
| Identification and experimental validation of demethylation-related genes in diabetic nephropathy. | Miao H et al. | — | 2025 | → |
| Identification and external validation of a prognostic signature based on hypoxia-glycolysis-related genes for kidney renal clear cell carcinoma. | Zhou Z et al. | — | 2025 | → |
| Identification and validation of biomarkers related to mitochondria-associated endoplasmic reticulum membranes in type 2 diabetes mellitus using peripheral blood transcriptomics. | Li S et al. | — | 2025 | → |
| Identification and validation of cell senescence genes in recurrent spontaneous abortion via multiple bioinformatics algorithms. | Wei Y et al. | — | 2025 | → |
| Identification and validation of diagnostic markers of atherosclerosis progression via bioinformatics strategies. | Mao Y et al. | — | 2025 | → |
| Identification and validation of efferocytosis-related biomarkers for the diagnosis of atherosclerosis based on bioinformatics and machine learning. | Fu X et al. | — | 2025 | → |
| Identification and Validation of Iron Metabolism-Related Biomarkers in Endometriosis: A Mendelian Randomization and Single-Cell Transcriptomics Study. | Du J et al. | — | 2025 | → |
| Identification and validation of key genes related to apoptosis in multiple organ dysfunction syndrome. | Zhang J et al. | — | 2025 | → |
| Identification and validation of microglia-associated genes in ischemic stroke using single-cell and bulk RNA-seq. | Qian D et al. | — | 2025 | → |
| Identification and validation of mitochondrial-related genes in intestinal ischemia-reperfusion injury based on WGCNA and machine learning. | Hu Y et al. | — | 2025 | → |
| Identification and validation of palmitoylation metabolism related biomarkers in osteoarthritis using transcriptomic and single cell RNA sequencing analyses. | Zhang D et al. | — | 2025 | → |
| Identification and validation of paraptosis-related biomarkers in recurrent miscarriage. | Wan Y et al. | — | 2025 | → |
| Identification and validation of prognostic genes and prognostic models associated with cutaneous melanoma and integrative stress response. | Zhang Z et al. | — | 2025 | → |
| Identification and validation of prognostic genes associated with m6A-regulated programmed cell death in acute lymphoblastic leukemia. | Zhang J et al. | — | 2025 | → |
| Identification and validation of selenium metabolism-related genes in lung adenocarcinoma prognosis using bioinformatics analysis. | Chen Y et al. | — | 2025 | → |
| Identification LEF1 as a Potential Novel Biomarker for Abdominal Aortic Aneurysms Based on Comprehensive Bioinformatics Analysis. | He P et al. | — | 2025 | → |
| Identification of a Novel Salivary Four-miRNA Signature for Non-Invasive Diagnosis of Oral Squamous Cell Carcinoma. | Ciringione A et al. | — | 2025 | → |
| Identification of a super enhancer associated gene signature for the prognosis prediction and regulatory mechanism exploration in breast cancer. | Li M et al. | — | 2025 | → |
| Identification of biomarkers of Shenhailong formula in benign prostatic hyperplasia treatment: An observation study using network pharmacology and Mendelian randomization analysis. | Pan J et al. | — | 2025 | → |
| Identification of cancer-associated fibroblast signature genes for potential biomarkers in cholangiocarcinoma: a Mendelian randomization study. | Hu S et al. | — | 2025 | → |
| Identification of Dendritic Cell-Associated Genes in COPD Based on Bioinformatics. | Huo Z et al. | — | 2025 | → |
| Identification of ferroptosis- and mitochondrial metabolism-related biomarkers and the potential molecular mechanisms of poor ovarian response. | Cai Y et al. | — | 2025 | → |
| Identification of iron metabolism-related key genes and exploration of their potential mechanisms in hemophagocytic lymphohistiocytosis based on transcriptome sequencing. | Fen L et al. | — | 2025 | → |
| Identification of Key Genes Associated with Endoplasmic Reticulum Stress in Calcium Oxalate Kidney Stones. | Tan Z et al. | — | 2025 | → |
| Identification of key genes related to lymphangiogenesis in venous thromboembolism through transcriptomics and verification by RT-qPCR. | Lin Y et al. | — | 2025 | → |
| Identification of lactylation-related biomarkers in HNSC by integrating machine learning and Spatial transcriptomics analysis. | Wang PY et al. | — | 2025 | → |
| Identification of LncRNAs Involved in the Salt Stress Responses of <i>Eurotium cristatum</i> and Functional Analysis of Their Roles in Morphological Differentiation and Metabolic Regulation. | Wang Y et al. | — | 2025 | → |
| Identification of marginal zone B cells in head and neck cancer with immunomodulatory characteristics. | Bao J et al. | — | 2025 | → |
| Identification of metabolic pathways modulated by GAM and NGAM in the inhibition of <i>Staphylococcus aureus</i> biofilm formation. | Afsharnia A et al. | — | 2025 | → |
| Identification of NEK6 as a potential biomarker for prognosis in glioma and its functional implications. | Wang D et al. | — | 2025 | → |
| Identification of Novel Biomarkers and Potential Therapeutic Targets for Systemic Sclerosis: An Integrated Analysis of Plasma Proteome-Wide Mendelian Randomization and Transcriptome. | Li H et al. | — | 2025 | → |
| Identification of novel gene expression programs in thrombin-stimulated hepatic stellate cells. | Mac NA et al. | — | 2025 | → |
| Identification of prognostic genes associated with sphingosine-1-phosphate in gastric cancer to construct a risk mode. | Han J et al. | — | 2025 | → |
| Identification of Three New Rugose Small Colony Variants from a <i>Pseudomonas aeruginosa</i> Biofilm. | Smartnick BK et al. | — | 2025 | → |
| Identification of two distinct molecular endotypes in cough-variant asthma based on sputum transcriptomics and clinical pathophysiological features. | Zhan W et al. | — | 2025 | → |
| Identifying key genes for European canker resistance in apple: machine learning and gene expression profiling of quantitative disease resistance. | Karlström A et al. | — | 2025 | → |
| Identifying key regulators in neuronal transdifferentiation by gene regulatory network analysis. | Li L et al. | — | 2025 | → |
| Identifying the causal role and therapeutic potential of immune-related genes in bladder cancer: a Mendelian randomization study. | Chen Y et al. | — | 2025 | → |
| IGHV1 usage is associated with lymphadenopathy and aggressive disease in the TCL1 mouse model for chronic lymphocytic leukemia. | Drothler S et al. | — | 2025 | → |
| Immune checkpoint expression in mucosal-associated invariant T cells is stimulus-dependent. | Clutter CH et al. | — | 2025 | → |
| Immunoglobulin M regulates airway hyperresponsiveness independent of T helper 2 allergic inflammation. | Hadebe S et al. | — | 2025 | → |
| Immunometabolic Dysregulation in B-Cell Acute Lymphoblastic Leukemia Revealed by Single-Cell RNA Sequencing: Perspectives on Subtypes and Potential Therapeutic Targets. | Sun D et al. | — | 2025 | → |
| Immunomodulatory effects and mechanisms of Qi-Xu-Tiao-Ti formula in Qi-deficiency constitution: a randomized controlled trial integrated with multi-omics and network pharmacology analysis. | Cui R et al. | — | 2025 | → |
| Impact of intermittent lead exposure on hominid brain evolution. | Joannes-Boyau R et al. | — | 2025 | → |
| Inactivation of Acetyl-CoA Acyltransferase 1 enhances the proliferation and motility of nasopharyngeal carcinoma cells. | Wei W et al. | — | 2025 | → |
| Inflammatory stromal and T cells mediate human bone marrow niche remodeling in clonal hematopoiesis and myelodysplasia. | Prummel KD et al. | — | 2025 | → |
| Insights into platypus crural gland transcriptomics - venom and beyond. | Gonsalvez A et al. | — | 2025 | → |
| Insights into salt adaptation from comparative genomics of Scirpus mariqueter and a related freshwater species. | Qin R et al. | — | 2025 | → |
| Integrated bioinformatics analysis of differences between EAC and ESCC. | Lyu Q et al. | — | 2025 | → |
| Integrated bioinformatics decoding of the MASLD ceRNA network reveals novel therapeutic targets. | Yu S et al. | — | 2025 | → |
| Integrated Bioinformatics Identifies NLRP3 Inflammasome Hub Genes and Therapeutic Targets in Schizophrenia. | Ma J et al. | — | 2025 | → |
| Integrated fibre-specific methylome and proteome profiling of human skeletal muscle across males and females with fibre-type deconvolution. | Palmer AS et al. | — | 2025 | → |
| Integrated metabolomics and lipidomics reveal fatty acid dysregulation in aortic dissection independent of hypertension. | Bai X et al. | — | 2025 | → |
| Integrated RNA-seq and snRNA-seq analysis identifies <i>PR10</i> tandem gene cluster governing early defense against <i>Fusarium wilt</i> in sea island cotton. | Liu B et al. | — | 2025 | → |
| Integrated single-cell multi-omics profiling reveals a senescence-associated hematopoietic landscape and regulatory network in aging bone marrow. | Zhang G et al. | — | 2025 | → |
| Integrated transcriptome study reveals a stress response state CD4 +T cells related to immune tolerance in breast cancer. | Gu J et al. | — | 2025 | → |
| Integrated transcriptomic and co-expression network analysis identifies <i>HIF1A</i> as a key immune regulator in biliary atresia. | Wang C et al. | — | 2025 | → |
| Integrating bioinformatics and molecular experiments to reveal the critical role of the cellular energy metabolism-related marker PLA2G1B in COPD epithelial cells. | Shi J et al. | — | 2025 | → |
| Integrating imaging and omics for enhanced subtyping of mild cognitive impairment associated with Alzheimer's disease. | Afxenti S et al. | — | 2025 | → |
| Integrating multi-omics to reveal the causal effect of gut microbiota on post-traumatic stress disorder and potential drug target analysis. | Huang H et al. | — | 2025 | → |
| Integrating single-cell RNA sequencing and spatial multi-omics reveals the molecular signature of regeneration after spinal cord injury. | Dong H et al. | — | 2025 | → |
| Integration of single cell and bulk transcriptomic analyses identifies FAM189A2 as a key prognostic gene in lung cancer. | Guo P et al. | — | 2025 | → |
| Integration of single-cell and RNA-seq analysis reveals sepsis heterogeneity and prognostic significance of FCGR3A+ Macrophage subtypes. | He Y et al. | — | 2025 | → |
| Integration of Transcriptome Profiling and Single-Cell Sequencing Analysis to Establish a CD8+ T Cell-Related Prognostic Model for Patients With NSCLC: From Assessment to Therapy. | Jiang YY et al. | — | 2025 | → |
| Integration of Whole-Genome Sequencing Analysis with Unique Patient-Derived Models Reveals Clinically Relevant Drug Targets in TFCP2 Fusion-Defined Rhabdomyosarcoma. | Bergsma P et al. | — | 2025 | → |
| Integrative Analysis of Gene Networks Associated with Adipose and Muscle Traits in Hanwoo Steers. | Hwang S et al. | — | 2025 | → |
| Integrative analysis of single-cell and bulk transcriptome data reveals age-related immune cell alterations in primary glioblastoma associated with prognosis. | Jing Z et al. | — | 2025 | → |
| Integrative brain omics approach highlights sn-1 lysophosphatidylethanolamine in Alzheimer's dementia. | Chen CY et al. | — | 2025 | → |
| Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation. | Du L et al. | — | 2025 | → |
| Integrative Bulk and Single-Cell Transcriptome Analyses Reveal Mitochondrial Metabolism-Related Biomarkers in IgA Nephropathy with Experimental Validation. | Wajid I et al. | — | 2025 | → |
| Integrative DNA methylation and transcriptome analysis reveal cell-type specific patterns in response to elevated allostatic load. | Emery O et al. | — | 2025 | → |
| Integrative gene co-expression network analysis reveals protein-coding and LncRNA genes associated with Alzheimer's disease pathology. | Zebardast F et al. | — | 2025 | → |
| Integrative Genomics and Multi-Tissue Transcriptomics Identify Key Loci and Pathways for Hypoxia Tolerance in Grass Carp. | Wang W et al. | — | 2025 | → |
| Integrative mendelian randomization and multi-omics analysis reveal a gut microbiota-metabolite-CXCL10 axis in breast cancer. | Qu J et al. | — | 2025 | → |
| Integrative multi-omics and causal inference reveal periodontal ligament cell-macrophage crosstalk under orthodontic force. | Jiang Y et al. | — | 2025 | → |
| Integrative Multi-Omics and Functional Validation Reveal the Role of the TACE Refractoriness-Associated Gene ATP1B3 in Hepatocellular Carcinoma. | Zhang C et al. | — | 2025 | → |
| Integrative MultiOmics and Machine Learning Reveal Peroxiredoxin 4 as a Critical Hub Governing Mitochondrial Dysfunction and B Cell Differentiation in Periodontitis. | Tu C et al. | — | 2025 | → |
| Integrative multi-omics and Mendelian randomization identify WWOX and THBS2 as potential therapeutic targets in mature T/NK-cell lymphoma. | Qin Y et al. | — | 2025 | → |
| Integrative Multi-Omics and Network Analyses Reveal Pathogenic and Protective Pathways in Centronuclear Myopathies. | Simon A et al. | — | 2025 | → |
| Integrative multi-omics reveals energy metabolism-related prognostic signatures and immunogenetic landscapes in lung adenocarcinoma. | Xie L et al. | — | 2025 | → |
| Integrative omics analysis reveals distinct adaptations of bongkrekic acid producing <i>Burkholderia gladioli pathovar cocovenenans</i> strains. | He J et al. | — | 2025 | → |
| Integrative Single-Cell and Machine Learning Analysis Develops a Glutamine Metabolism-Based Prognostic Model and Identifies MSMO1 as a Therapeutic Target in Osteosarcoma. | Ma H et al. | — | 2025 | → |
| Integrative single-cell and spatial transcriptomics analysis reveals FLAD1 as a regulator of the immune microenvironment in hepatocellular carcinoma. | Zhu P et al. | — | 2025 | → |
| Integrative Transcriptomic and Machine Learning Analysis Identifies Key Senescence-Associated Secretory Phenotype Genes Associated With Immune Dysregulation in Periodontitis. | Zeng J et al. | — | 2025 | → |
| Integrative transcriptomic and single-cell analysis reveals mitochondrial-related gene biomarkers in heart failure with preserved ejection fraction. | You H et al. | — | 2025 | → |
| Interactions of Antibody Drug Conjugate Anti-Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy. | Lesperance J et al. | — | 2025 | → |
| Interferons Inhibit Ebola Virus Infection of Human Keratinocytes. | Elliff J et al. | — | 2025 | → |
| Intergenerational effects of early life protein restriction on adipose tissue development as revealed by sheep transcriptomic analyses. | Alonso-García M et al. | — | 2025 | → |
| Intrauterine growth restriction induces persistent adipose inflammation and metabolic abnormalities in rats among various postnatal growth trajectories. | Hu Q et al. | — | 2025 | → |
| Intrinsic changes in cell differentiation and identity drive impaired wound healing in aged female murine skin. | Dube CT et al. | — | 2025 | → |
| Intrinsic dysfunction in muscle stem cells lacking dystrophin begins during secondary myogenesis. | Esper ME et al. | — | 2025 | → |
| Investigating key genes and molecular mechanisms of prostate cancer and coronary heart disease through transcriptomics and experimental validation. | Wu N et al. | — | 2025 | → |
| Investigating the expression of hsa_circ_0036722/hsa-miR-503-5p/PDCD4 axis in esophageal cancer. | Marhamati S et al. | — | 2025 | → |
| Investigating the prognostic potential of PTPN11 gene in papillary thyroid carcinoma: A comprehensive study of bulk and single cell transcriptome. | Wang H et al. | — | 2025 | → |
| Investigating the Role of Glycolysis in Xuefu Zhuyu Capsule-Promoted Angiogenesis in Endothelial Cells: A Study Based on Network Pharmacology, Molecular Docking, and In Vitro Validation. | Lin F et al. | — | 2025 | → |
| Investigation of radiation-induced DNA damage repair-related genes as diagnostic biomarkers for radiation. | Zhang Q et al. | — | 2025 | → |
| IRF7 orchestrates proinflammatory macrophage polarization and joint destruction in rheumatoid arthritis. | Liu H et al. | — | 2025 | → |
| Jaw-specific differential kinase activity profiles in human periodontal ligament stem cells under mechanical compression. | Niederau C et al. | — | 2025 | → |
| Joint analysis of <i>de novo</i> mutations from autism spectrum disorder, schizophrenia, congenital heart disease, and other developmental disorders improves detection power and implicates shared molecular pathways and CNS processes. | Kealhofer M et al. | — | 2025 | → |
| Key genes associated with the comorbidity of allergic rhinitis and chronic rhinosinusitis with nasal polyps: Identification, experimental validation, and an observational study using transcriptomic profiling and Mendelian randomization analysis in humans. | Hu X et al. | — | 2025 | → |
| KLF5 facilitates lung adenocarcinoma metastasis by regulating the epithelial-mesenchymal transition pathway through RHPN2. | Zhang T et al. | — | 2025 | → |
| Kmo restricts Salmonella in a whole organism infection model by promoting macrophage lysosomal acidification through kainate receptor antagonism. | Goering ER et al. | — | 2025 | → |
| Lactylation-related gene signatures define immune heterogeneity and provide diagnostic biomarkers for periodontitis. | Zhu Y et al. | — | 2025 | → |
| Laminar CD34+ membranous cells with mechanosensitive properties in subcutaneous fascia of the abdominal midline. | Huang H et al. | — | 2025 | → |
| Late-acting self-incompatibility in Asimina triloba: implications for the evolution of self-incompatibility in angiosperms. | Ferrer-Blanco C et al. | — | 2025 | → |
| Lipid deprivation amplifies type I IFN responses in monocytes through prenylation: insights from familial combined hypolipidemia type 2. | Pinzon Grimaldos A et al. | — | 2025 | → |
| Lipidomic changes in persister cancer cells drive enhanced ferroptosis sensitivity. | Reznik E et al. | — | 2025 | → |
| Live attenuated influenza vaccine with low proportions of defective interfering particles elicits robust immunogenicity and cross-protection. | Wu M et al. | — | 2025 | → |
| Long-read sequencing reveals genomic and epigenomic variation in the dark genome of human Alzheimer's disease. | Ramirez P et al. | — | 2025 | → |
| Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC. | Ouologuem L et al. | — | 2025 | → |
| Low dose IFNγ remodels enhancer landscape to potentiate mesenchymal stromal cell activation. | Lin J et al. | — | 2025 | → |
| L-proline supplementation affects non-volatile flavour perception through oral microbiome metabolic pathways. | Zhang S et al. | — | 2025 | → |
| <i>BCL6</i>, <i>DUSP3</i>, and <i>IL6R</i> Are Identified as Shared Druggable Immune-Regulatory Axis in Atrial Fibrillation and Atherosclerosis Through Integrative In Silico and In Vitro Analysis. | Zheng H et al. | — | 2025 | → |
| <i>CCT4</i> as a prognostic biomarker correlated with immune infiltration and hepatocyte dedifferentiation in hepatocellular carcinoma. | Zhang X et al. | — | 2025 | → |
| <i>Mafb</i> deficiency in myeloid cells increases susceptibility to <i>Mycobacterium tuberculosis</i> infection in mice. | Hikichi H et al. | — | 2025 | → |
| Machine learning-based screening and validation of pyroptosis-associated prognostic genes and potential drugs in cervical cancer. | Hou Z et al. | — | 2025 | → |
| Machine learning-driven comprehensive profiling of tumor heterogeneity and sialylation in hepatocellular carcinoma. | Tang K et al. | — | 2025 | → |
| Machine learning-enabled non-targeted metabolomics reveals nutritional and metabolic responses of Brachypodium distachyon to drought and elevated CO2. | Chang HF et al. | — | 2025 | → |
| Machine learning-enhanced discovery of a basement membrane-related gene signature in glioblastoma via single-cell and Spatial transcriptomics. | Liu Z et al. | — | 2025 | → |
| Machine learning identifies exosome related gene signatures for early prediction of non-small cell lung cancer. | Zeng L et al. | — | 2025 | → |
| Macrophage migration inhibitory factor-CD74 axis drives vascular smooth muscle cell-induced M1 macrophage polarization to exacerbate intracranial aneurysm inflammation. | Chen Y et al. | — | 2025 | → |
| Macrophages in tertiary lymphoid structures promote apoptosis of ATF4-positive gastric cancer cells via IL18. | Zhou L et al. | — | 2025 | → |
| Mapping the BCSC-1 interactome in breast cancer. | Ma Y et al. | — | 2025 | → |
| Mapping the FOXA1 Interactome in ER+ Breast Cancer Cells Using Proximity Labeling Reveals Novel Interactions with the Orphan Nuclear Receptor NR2C2. | Plagens RN et al. | — | 2025 | → |
| MARCO+ Tumor-Associated Macrophages Impede CD8+ T Cell Immunity to Facilitate Immunotherapy Resistance in Renal Cell Carcinoma. | Chen J et al. | — | 2025 | → |
| Maternal diabetes programs sexually dimorphic early-onset cardiovascular dysfunction in metabolically healthy offspring. | Zhao A et al. | — | 2025 | → |
| Maternal dietary fibre intake results in sex-specific single-cell molecular changes in the heart of the offspring. | Yang C et al. | — | 2025 | → |
| Mathematical strategies for predicting resistant subpopulations from scRNAseq data of a PANC-1 3D tissue model: Insight into gemcitabine resistance and TGFB1-induced invasion and EMT. | Caliskan A et al. | — | 2025 | → |
| MDM2 promotes CELF6 ubiquitination-dependent degradation to promote neuroblastoma cell proliferation. | Zhao Z et al. | — | 2025 | → |
| Mechanistic insights into Shenqi Dihuang decoction in the treatment of immunoglobulin a nephropathy. | Gao Y et al. | — | 2025 | → |
| Mendelian Randomization Suggests a Causal Link Between Glycemic Traits and Thoracic Aortic Structures and Diseases. | Daria T et al. | — | 2025 | → |
| Meta-Analysis of Ocy-454 Showed Interrupted Osteocyte Maturation in Spaceflight Affects SOST Expression and Hypoxic Response. | Honjo M et al. | — | 2025 | → |
| Metabolic reprogramming and M2 macrophage depletion define the microenvironment of adenomyosis. | Bian X et al. | — | 2025 | → |
| Metabolic reprogramming signature predicts immunotherapy efficacy in lung adenocarcinoma: Targeting <i>SLC25A1</i> to overcome immune resistance. | Zhang P et al. | — | 2025 | → |
| Metabolic syndrome-related gene signature for prognosis and immune microenvironment prediction in hepatocellular carcinoma. | Chen L et al. | — | 2025 | → |
| Metalloproteinase-9 as a Pyroptosis-Hypoxia Synergy Effector Drives Immune Remodeling in Ischemic Stroke: A Multi-Omics Validated Diagnostic Biomarker and Therapeutic Target. | Wu J et al. | — | 2025 | → |
| MFSD12 promotes proliferation, metastasis and invasion of hepatocellular carcinoma cells and its potential correlation with HAVCR2/LGALS9 immune checkpoint axis. | Sun K et al. | — | 2025 | → |
| Microbial Product Cocktails for Personalized Cancer Immunotherapy. | Yan Y et al. | — | 2025 | → |
| Microbial production of short-chain fatty acids attenuates long-term neurologic impairment after traumatic brain injury. | Xiong Z et al. | — | 2025 | → |
| Microbiota shape the colon epithelium controlling inter-crypt absorptive goblet cells via butyrate-GP R109A signalling. | Dias Nirello V et al. | — | 2025 | → |
| Microglial Prrc2a regulates microglia-neuron interaction in cerebellum and motor functions in mice. | Li X et al. | — | 2025 | → |
| MITF regulates autophagy and extracellular vesicle cargo in gastrointestinal stromal tumors. | Proaño-Pérez E et al. | — | 2025 | → |
| Mitochondrial energy metabolism genes as prognostic biomarkers in clear cell renal cell carcinoma via single-cell and bulk RNA sequencing analyses. | Peng Y et al. | — | 2025 | → |
| Mitochondrial Imaging and Transcriptome Analysis of Bone Mesenchymal Stem Cells During Osteogenesis Under Different Culture Conditions. | Li Q et al. | — | 2025 | → |
| Mitochondrial structure and function in OCRL depleted cells. | Philip RG et al. | — | 2025 | → |
| Mitophagy-associated biomarkers and macrophage involvement in pulmonary arterial hypertension: identification and functional implications. | Zhang X et al. | — | 2025 | → |
| MMP-9 affects dural cell composition and granulocyte accumulation during neuroinflammation. | Shen SH et al. | — | 2025 | → |
| Molecular Encoding of Ischemic Stroke and its Resolution after Human Neural Stem Cell Therapy by Extracellular Vesicles. | Chang C et al. | — | 2025 | → |
| Molecular insights into the role of desmin intermediate filament network in chromatin landscape, cardiomyocyte differentiation, and maturation. | Tsikitis M et al. | — | 2025 | → |
| Molecular profiling of the Basal-like intrinsic molecular subtype in primary ER-positive HER2-negative breast cancer. | Hohmann L et al. | — | 2025 | → |
| Mpox virus OPG175 negatively regulates viral replication by controlling Wnt signaling. | Nakata Y et al. | — | 2025 | → |
| Multi-ancestry genome-wide association meta-analysis identifies candidate genes for computed tomography-based carcass composition traits in pigs. | Han H et al. | — | 2025 | → |
| Multilayer regulation underlies the functional precision and evolutionary potential of the olfactory system. | Mermet J et al. | — | 2025 | → |
| Multi-omic analysis of PBMCs in sepsis reveals widespread cytotoxic dysfunction and an increased population of <i>CD69</i> expressing naïve CD4+ T cells. | Flynn J et al. | — | 2025 | → |
| Multi-omics analyses identify mannose phosphate isomerase-centered hypoxia-induced angiogenesis signature in colorectal cancer. | Liu S et al. | — | 2025 | → |
| Multi-Omics Analyses Reveal the Antifungal Mechanism of Phenazine-1-Carboxylic Acid Against <i>Pseudogymnoascus destructans</i>. | Huang Z et al. | — | 2025 | → |
| Multi-omics analysis reveals that ALYREF-mediated m<sup>5</sup>C modification promotes platinum resistance in ovarian cancer via the NSUN2/ALYREF/LGR4 axis. | Yang S et al. | — | 2025 | → |
| Multi-omics analysis reveals the effects of prenatal nutrition on carcass-related tissues in beef cattle. | Polizel GHG et al. | — | 2025 | → |
| Multi-omics and experimental validation identify methylation-related genes and METTL16 as key regulators in diabetic foot ulcer pathogenesis. | Tong Y et al. | — | 2025 | → |
| Multi-omics identification and validation of oxidative phosphorylation-related hub genes in schizophrenia. | Zhou Y et al. | — | 2025 | → |
| Multi-omics identify hallmark protein and lipid features of small extracellular vesicles circulating in human plasma. | Rai A et al. | — | 2025 | → |
| Multi-Omics Integration Identifies FGF1 as a Diagnostic Biomarker and RAS-MAPK-Driven Pathogenic Factor in Osteoarthritis. | Yan Y et al. | — | 2025 | → |
| Multi-omics integration of transcriptome, miRNA, and metabolome uncovers molecular mechanisms of male flower development in cucumber line B10 (Cucumis sativus L.). | Turek S et al. | — | 2025 | → |
| Multi-Omics Integration Reveals Electroacupuncture Ameliorates Cognitive Impairment in Alzheimer's Disease via Gut-Brain Axis. | Zhang S et al. | — | 2025 | → |
| Multi-Omics Investigation into Why Viable Oogonial Stem Cells Can Still Be Isolated and Cultured from Post-Mortem <i>Paralichthys olivaceus</i>. | Ren Y et al. | — | 2025 | → |
| Multi-omics spatial characteristics of CD8<sup>+</sup>TRM cells in hepatocellular carcinoma and immunotherapy response prediction. | Li S et al. | — | 2025 | → |
| Multi-omics unravel heterogeneity of glucose metabolism reprogramming in gastric cancer. | Liang L et al. | — | 2025 | → |
| Multi-target mechanism of 6-O-Caffeoylarbutin in hyperuricemia treatment through <i>in vivo</i> validation and network pharmacology. | Zhang Y et al. | — | 2025 | → |
| Multi-trait association analysis reveals shared genetic architecture between lung cancer and cardiometabolic diseases. | Lyu Q et al. | — | 2025 | → |
| Mutational disruption of transcription factors binding and regulatory networks in a case of unexplained total fertilization failure. | Ata M et al. | — | 2025 | → |
| MX1 is a novel crucial prognostic and therapeutic target inducing chemoresistance in right-sided colon cancer: insights from machine learning-based multi-omics analysis. | Hou Y et al. | — | 2025 | → |
| Myeloperoxidase inhibits prostate cancer progression, suppresses the PI3K/AKT signaling pathway and reshapes the immune microenvironment. | Zhou M et al. | — | 2025 | → |
| Network pharmacology and molecular dynamics simulation elucidate the potential mechanism of Batatasin-III in Bletilla striata against ulcerative colitis. | Tong Y et al. | — | 2025 | → |
| Neural and molecular changes during a mind-body reconceptualization, meditation, and open label placebo healing intervention. | Jinich-Diamant A et al. | — | 2025 | → |
| Neuroprotective effects of Berberine-loaded BMSCs-apoptotic extracellular vesicles on retinal ganglion cells: therapeutic potential for glaucomatous injury. | You M et al. | — | 2025 | → |
| Neutrophil-derived Il1r2 modulates inflammation and alleviates acute lung injury by promoting M2 macrophage polarization. | Ding W et al. | — | 2025 | → |
| New insights into keloid pathogenesis: biomarker potential for CDK7 and DDB2. | Zhang W et al. | — | 2025 | → |
| Next Generation Risk Assessment of Emerging PFOA Alternatives Using Integrated New Approach Methodologies. | Song Y et al. | — | 2025 | → |
| N-Lactoyl amino acids: insights from metabolite genome-wide association studies and phenome-wide association analysis. | Elashi AA et al. | — | 2025 | → |
| Novel biallelic MEI1 variants cause female infertility characterized by multiple pronuclei formation and aberrant embryonic development. | Jiao X et al. | — | 2025 | → |
| Novel hypoxia-immune biomarkers predict response to neoadjuvant chemotherapy in patients with laryngo-hypopharyngeal cancer. | Wang L et al. | — | 2025 | → |
| Nucleosome assembly protein-like 1 degradation-dependent novel cardioprotection mechanism of Wnt2 against ischemia‒reperfusion injury. | Wang Y et al. | — | 2025 | → |
| Observational study on the molecular mechanism and experimental verification of m6A RNA methylation modification related genes in venous thromboembolism. | Lin B et al. | — | 2025 | → |
| Omics-derived biological modules reflect tau positron emission tomography in Alzheimer's disease. | Gu SC et al. | — | 2025 | → |
| Oncofetal dual‑specificity phosphatase 9 drives stem-like properties through ERK1/2-PPARG-SCD axis-mediated lipid metabolism in hepatocellular carcinoma. | Peng W et al. | — | 2025 | → |
| Oncostatin M induced by STAT5-activating oncogenes promotes disease progression in hematologic malignancies. | Rassner M et al. | — | 2025 | → |
| Optimised dissociation and multimodal profiling of prostate cancer stroma reveal fibromuscular cell heterogeneity with clinical correlates. | Damisch E et al. | — | 2025 | → |
| Optineurin Shapes Basal and LPS-Induced Transcriptomes in BV2 Microglia. | Cappelli S et al. | — | 2025 | → |
| Pan-cancer analyses identify oncogenic drivers, expression signatures, and therapeutic vulnerabilities in RHO GTPase pathway genes. | Fernández R et al. | — | 2025 | → |
| Pan-cancer analysis and experimental verification of its roles and clinical significance of SLC2A3 in kidney renal clear cell carcinoma. | Lyu Z et al. | — | 2025 | → |
| Panmim: a resource of pan-cancer metastasis immune microenvironment. | Zhang X et al. | — | 2025 | → |
| Paraptosis-related genes regulate tumor immune microenvironment and predict prognosis in breast cancer. | Dong Z et al. | — | 2025 | → |
| Partial restoration of mitochondrial dysfunction by AAV-Ant1 protects from dilated cardiomyopathy in Ant1<sup>-/-</sup> plus mtDNA mutant mice. | Angelin A et al. | — | 2025 | → |
| Paternal valproate use and impact of shared genetic susceptibility on child neurodevelopment. | Olstad EW et al. | — | 2025 | → |
| PAX3-FOXO1 Drives Targetable Cell State-Dependent Metabolic Vulnerabilities in Rhabdomyosarcoma. | Paras KI et al. | — | 2025 | → |
| PCK1 attenuates intrahepatic cholangiocarcinoma progression by suppressing lactate accumulation and PI3K-AKT signaling. | Pei Y et al. | — | 2025 | → |
| PCM1 coordinates centrosome asymmetry with polarized endosome dynamics to regulate daughter cell fate. | Zhao X et al. | — | 2025 | → |
| PDGFRα+ fibroblast ablation exacerbates pathologic features in a model of house dust mite-induced allergenic asthma. | Shin HE et al. | — | 2025 | → |
| Pericyte-myofibroblast transition: a novel mechanism in peritoneal fibrosis and the effect of Asiaticoside. | Shi J et al. | — | 2025 | → |
| Peripheral and intrahepatic B-cell subsets contribute to HBeAg seroconversion in patients with chronic hepatitis B. | Zuo J et al. | — | 2025 | → |
| PGAP2: A comprehensive toolkit for prokaryotic pan-genome analysis based on fine-grained feature networks. | Bu C et al. | — | 2025 | → |
| Phospholipid scramblase 1 (PLSCR1) regulates interferon-lambda receptor 1 (IFN-λR1) and IFN-λ signaling in influenza A virus (IAV) infection. | Yang AX et al. | — | 2025 | → |
| Phosphoproteomic profiling of lipopolysaccharide stimulated toll-like receptor pathways in macrophages. | Kim D et al. | — | 2025 | → |
| Piezo1 regulates the mechanotransduction of soft matrix viscoelasticity. | A G Oliva M et al. | — | 2025 | → |
| Platelet derived growth factor-AB modulates post-infarct myocardium leading to extended improvement in cardiac function. | Deshmukh T et al. | — | 2025 | → |
| Platelet Gene Expression in Systemic Lupus Erythematosus and Cardiovascular Health. | Muller MA et al. | — | 2025 | → |
| Polyadenylation landscape of in vivo long-term potentiation in the rat brain. | Gumińska N et al. | — | 2025 | → |
| Polygenic risk for white matter hyperintensities is associated with early cerebrovascular events partly through hemodynamic measures in cognitively unimpaired middle-aged and older adults with low cardiovascular risk. | Genius P et al. | — | 2025 | → |
| Polystyrene nanoplastics disrupt epididymal initial segment by perturbing NK cell differentiation and epithelial homeostasis. | Chen T et al. | — | 2025 | → |
| Posterior enhancer (p-Enh) maintains early neuromesodermal progenitors bi-potency during gastrulation. | Mi P et al. | — | 2025 | → |
| Post-replicative initial expression of PAX6 during neuroectoderm differentiation. | Hu S et al. | — | 2025 | → |
| Potential glutamine metabolism-related biomarkers were identified in osteoarthritis by bioinformatics. | Li D et al. | — | 2025 | → |
| PPIF<sup>+</sup> neutrophils promote mtROS driven NETosis mediated progression of colorectal cancer. | Ying Y et al. | — | 2025 | → |
| PRDX1 promotes testosterone synthesis and attenuates aging via redox regulation of ATG4B to modulate lipophagy. | Zhang H et al. | — | 2025 | → |
| Predicting Driver Genes From Multi-Omics Data Using Hierarchical Multi-Feature Synergy Model. | Hu Z et al. | — | 2025 | → |
| Pretreatment with Silver Thiosulfate Increases the Auxin-Inductive Effect for Rooting Mature Chestnut Shoots. | Castro-Camba R et al. | — | 2025 | → |
| Preventing effect of plant extracts and omega-3 on age-related cognitive decline in male mice. | Martin M et al. | — | 2025 | → |
| Prognostic and immunological implications of sialylation-associated gene signatures in hepatocellular carcinoma. | Wang GQ et al. | — | 2025 | → |
| Prognostic differential subpopulation classification and immunotherapy response prediction in pancreatic cancer patients based on the gene features of necrotizing apoptosis. | Liao K et al. | — | 2025 | → |
| Prognostic value and biological role of STING-related genes GAB3 and IL16 in lung adenocarcinoma: implications for immune evasion and treatment. | Ji T et al. | — | 2025 | → |
| Prognostic value of brown adipocyte-related genes in colorectal cancer: a multi-omics and Mendelian randomization study. | He H et al. | — | 2025 | → |
| Prognostic value of fatty acid metabolism-related signature and integrated analysis of the immune microenvironment in multiple myeloma. | Yu Y et al. | — | 2025 | → |
| Proliferation-cycle gene signatures predict immune landscape and prognosis in lung adenocarcinoma. | Lin C et al. | — | 2025 | → |
| Proteomic signatures of smoking and their associations with risk of incident diseases and mortality in diverse populations. | Xiao S et al. | — | 2025 | → |
| PTGS2 Is Involved in Osteonecrosis of the Femoral Head and Bone Marrow Edema. | Lin C et al. | — | 2025 | → |
| Quantifying Early-Stage Lung Adenocarcinoma Progression with a Radiomic Trajectory. | Qiu ZB et al. | — | 2025 | → |
| Quercetin reverses β<sub>1</sub>-adrenoceptor autoantibody-induced heart failure by promoting MDM2-mediated ubiquitination and degradation of <i>p53</i> in cardiomyocytes. | Ma M et al. | — | 2025 | → |
| R3HDM4 influences kidney renal clear cell carcinoma progression, immune modulation, and potential links to the IGSF8 immune checkpoint. | Sun K et al. | — | 2025 | → |
| RAMEN: Dissecting individual, additive and interactive gene-environment contributions to DNA methylome variability in cord blood. | Navarro-Delgado EI et al. | — | 2025 | → |
| Remodeling Cell Adhesion Releases Cardiac Potential of Human Pluripotent Stem Cells with Continuous Proliferation and Accelerated Maturation. | Liu W et al. | — | 2025 | → |
| Retrospective analysis of metabolism-related genes in endometrial carcinoma: links to prognosis and immunity. | Lin Q et al. | — | 2025 | → |
| Retrospective transcriptomic analysis indicates temporal dysregulation of mitochondrial genes and metabolic pathways after volumetric muscle loss injury. | Miller DL et al. | — | 2025 | → |
| Revealing the genetic architectures underlying organ-specific aging based on proteomic data. | Zhu RJ et al. | — | 2025 | → |
| Rheumatoid Arthritis and Fibromyalgia Syndrome: A Bibliometric and Bioinformatics Perspective on Comorbidity Research. | Chen G et al. | — | 2025 | → |
| RhoE downregulation leads to enhanced cholesterol biosynthesis and sorafenib resistance in hepatocellular carcinoma. | Feng J et al. | — | 2025 | → |
| RNA binding of GAPDH controls transcript stability and protein translation in acute myeloid leukemia. | Shamloo S et al. | — | 2025 | → |
| RNF115 upregulation by YBX1-dependent m5C modification promotes hepatocellular carcinoma progression. | Li J et al. | — | 2025 | → |
| RpoS impacts global gene expression and carbon source utilization in <i>Escherichia coli</i> O104:H4. | Berger P et al. | — | 2025 | → |
| RRS1 regulates proliferation, migration, and invasion of HTR-8/SVneo human trophoblasts. | Wu Y et al. | — | 2025 | → |
| Saliva from oral squamous cell carcinoma patients promotes tumor progression via Inflammation, stromal remodeling, and metabolic reprogramming in a mouse model. | Zhang XY et al. | — | 2025 | → |
| Saturating the eQTL map in Drosophila: Genome-wide patterns of cis and trans regulation of transcriptional variation in outbred populations. | Pallares LF et al. | — | 2025 | → |
| scFFPE-ATAC enables high-throughput single cell chromatin accessibility profiling in formalin-fixed paraffin-embedded samples. | Yadav RP et al. | — | 2025 | → |
| Scoring information integration with statistical quality control enhanced cross-run analysis of data-independent acquisition proteomics data. | Gao M et al. | — | 2025 | → |
| Screening and predictive analysis of common regulatory genes in diabetes and rectal cancer: transcriptional and drug modulation mechanisms. | Wu S et al. | — | 2025 | → |
| Seed metabolites headstart haustoriogenesis and potentiate aggressiveness of parasitic weeds. | Brun G et al. | — | 2025 | → |
| Serum vesicle biomarkers reflect the disease activity of idiopathic pulmonary fibrosis. | Shirai Y et al. | — | 2025 | → |
| Shared diagnostic genes and potential mechanism between allergic rhinitis and atopic dermatitis revealed by integrated transcriptomic analysis and machine learning. | Zhang X et al. | — | 2025 | → |
| Shifted assembly and function of mSWI/SNF family subcomplexes underlie targetable dependencies in dedifferentiated endometrial carcinomas. | St Laurent JD et al. | — | 2025 | → |
| SHMT2 modulates the transcriptome and metabolism profiles to promote the tumor phenotypes of bladder cancer HT-1376 cells. | Guo X et al. | — | 2025 | → |
| Short tandem repeats in populations of the Qinghai-Tibet Plateau and adjacent regions provide insights into high-altitude adaptation. | Huang Y et al. | — | 2025 | → |
| Sialylation-related gene signature predict prognosis and immunotherapy efficacy in low- and high-grade glioma: a PCA-based stratification study. | Zhu G et al. | — | 2025 | → |
| Single-cell analysis indicating CCR8 modulates CD8<sup>+</sup> tissue-resident memory T cells to attenuates rejection in transplantation. | Wang X et al. | — | 2025 | → |
| Single-cell analysis of microglial activation after traumatic brain injury reveals immune signaling pathways linked to mitochondrial dysfunction and brain aging. | Sun M et al. | — | 2025 | → |
| Single-cell analysis of testicular bacterial microbiome changes during aging and effect on reproductive capacity in mice. | Zhou J et al. | — | 2025 | → |
| Single-cell analysis of tumor microenvironment immune homeostasis and identification of prognostic biomarkers in head and neck squamous cell carcinoma. | Xie H et al. | — | 2025 | → |
| Single-cell analysis reveals shared adaptive responses across different types of podocyte injury. | Yang L et al. | — | 2025 | → |
| Single-cell and spatial transcriptomic characterization of pulmonary pleomorphic carcinoma. | Matsuoka A et al. | — | 2025 | → |
| Single cell and spatial transcriptomic profiling of the type 2 diabetic coronary microcirculation and myocardium. | McCallinhart PE et al. | — | 2025 | → |
| Single-cell hdWGCNA identifies ICI-related-colitis key CD8 + T cells linked to immunotherapy response and prognosis in colon cancer. | Wu S et al. | — | 2025 | → |
| Single-Cell Heterogeneity of Epigenetic Factor Regulation Deciphers Alteration of RNA Metabolism During Proliferative SHH-Medulloblastoma. | Francés R et al. | — | 2025 | → |
| Single-cell landscape of the tumour immune microenvironment in human gynaecologic malignancies. | Yin S et al. | — | 2025 | → |
| Single-cell multi-omics analysis revealed the expansion of age-associated B cells in the pancreas of type 1 autoimmune pancreatitis patients. | Wang J et al. | — | 2025 | → |
| Single-cell multi-omics identifies metabolism-linked epigenetic reprogramming as a driver of therapy-resistant medulloblastoma. | Veo B et al. | — | 2025 | → |
| Single cell RNA-seq analysis associates Osm signaling in macrophages with osteogenic differentiation during heterotopic ossification. | Wang J et al. | — | 2025 | → |
| Single-cell RNA-seq reveals breast cancer heterogeneity and identifies TCP1 as a therapeutic target in breast cancer. | Wu H et al. | — | 2025 | → |
| Single-cell RNA sequencing defines prognostic subtypes and identifies AIF1L as a therapeutic target in colorectal cancer. | Li G et al. | — | 2025 | → |
| Single-cell RNA sequencing reveals immune cell alterations in patients with allergic rhinitis treated with Peiyuan Tong-qiao decoction. | Li J et al. | — | 2025 | → |
| Single-cell RNA sequencing reveals immune cell dysfunction and rewired interaction networks in the peripheral blood of active tuberculosis patients. | Wei Y et al. | — | 2025 | → |
| Single Cell Sequencing Identifies Distinct Cellular Alterations in Impaired Aged and Diabetic Wounds. | Rojas Cortez L et al. | — | 2025 | → |
| Single-Cell Sequencing Unravels Pancreatic Cancer: Novel Technologies Reveal Novel Aspects of Cellular Heterogeneity and Inform Therapeutic Strategies. | Chen K et al. | — | 2025 | → |
| Single-cell transcriptome analyses reveal disturbed decidual microenvironment in women of advanced maternal age. | Xie H et al. | — | 2025 | → |
| Single-cell transcriptomic insights into ccRCC: a stemness gene signature for prognosis and treatment response prediction. | Chen J et al. | — | 2025 | → |
| Single-cell transcriptomic profiling reveals aberrant CD4⁺ naive T cell differentiation driving immune activation in Behçet's uveitis. | Zhang L et al. | — | 2025 | → |
| Single-cell transcriptomics reveals mechanisms of <i>Galt</i> gene editing-induced liver injury involving HGF-VEGF-mediated intercellular signaling in mice. | Li Z et al. | — | 2025 | → |
| Single-cell transcriptomics reveals pathogen interactions and T cell reprogramming in HIV and <i>Mycobacterium tuberculosis</i> co-infection. | Zhao Z et al. | — | 2025 | → |
| Single-cell transcriptomics reveals stepwise transformation of epithelial cells into Non-Professional Phagocytes. | Almeida Machado Costa C et al. | — | 2025 | → |
| Single-cell transcriptomics uncovering a critical AKT-LONP1-STAR axis in ovarian hyperandrogenism of PCOS. | Zhang C et al. | — | 2025 | → |
| Single-Cell Transcriptomics Uncovers Cellular Heterogeneity, Mechanisms, and Therapeutic Targets for Ferroptosis-Related Genes in Parkinson's Disease. | Liu M et al. | — | 2025 | → |
| Single-Cell Transcriptomics Unravels Growth Factor Erv1-Like Mediated Ferroptosis as a Key Driver of Intestinal Epithelial Dysfunction in Ulcerative Colitis. | Song Y et al. | — | 2025 | → |
| Six1-Eya1 Axis Governs Myofiber Remodeling and Fibrosis in Extraocular Myopathy: Insights from Single-Cell RNA Sequencing and Mesenchymal Stem Cell Therapy in Thyroid Eye Disease. | Shin HA et al. | — | 2025 | → |
| Six Drivers of Aging Identified Among Genes Differentially Expressed With Age. | Coler-Reilly A et al. | — | 2025 | → |
| Small Extracellular Vesicles Secreted by Cisplatin-Resistant Neuroblastoma Cells Increase Lactate Secretion and Alter Metabolic Pathways in Primary Human Umbilical Vein Endothelial Cells (HUVECs). | Frawley T et al. | — | 2025 | → |
| Spatial dynamics of brain development and neuroinflammation. | Zhang D et al. | — | 2025 | → |
| Spatial-reprogramming derived GPNMB<sup>+</sup> macrophages interact with COL6A3<sup>+</sup> fibroblasts to enhance vascular fibrosis in glioblastoma. | Du Y et al. | — | 2025 | → |
| Spatial transcriptomics reveals unique inflammatory signatures across all anatomic locations in postoperative Crohn's disease. | Battat R et al. | — | 2025 | → |
| Spatiotemporal dynamics of age-related genes and the regulatory network of LaAGL2-3 in Larix kaempferi (Lamb.) Carr. based on the latest genome annotation. | Liao TQ et al. | — | 2025 | → |
| SPP1, LYZ, and MCM5: potential diagnostic biomarkers for rheumatoid arthritis and cervical cancer comorbidity. | Liu X et al. | — | 2025 | → |
| SPP1 + macrophage and Treg interaction mediates immunosuppression and adverse survival in HER2 + breast cancer. | Gao H et al. | — | 2025 | → |
| Srcap Chromatin Remodeler Is Required for Efficient Replication Dynamics in Mammalian Cells. | Dzhokova SK et al. | — | 2025 | → |
| STAT3 S727 phosphorylation drives pathogenic Th17 differentiation and neuroinflammation in autoimmune disease. | Prado DS et al. | — | 2025 | → |
| Stc2a inhibits IGF-stimulated somatic growth in favor of organismal survival under hypoxic stress. | Wang Z et al. | — | 2025 | → |
| Stress-induced toxic genomic R-loops support biofilm extracellular matrix formation. | Mugunthan S et al. | — | 2025 | → |
| Structural and Functional Analysis of ASFV pI73R Reveals GNB1 Binding and Host Gene Modulation. | Dolata KM et al. | — | 2025 | → |
| stTransfer enables transfer of single-cell annotations to spatial transcriptomics with single-cell resolution. | Zhou T et al. | — | 2025 | → |
| Study on the spatiotemporal regulation of interferon-stimulated genes during Zika virus infection. | Chen XZ et al. | — | 2025 | → |
| Subgroup of meningiomas involving FOS and FOSB gene fusions. | Yalcin K et al. | — | 2025 | → |
| Super-enhancer profiling reveals ThPOK/ZBTB7B, a CD4<sup>+</sup> cell lineage commitment factor, as a master regulator that restricts breast cancer cells to a luminal non-migratory phenotype. | Arcuschin CD et al. | — | 2025 | → |
| SurprisalAnalysis: an open-source software for information-theoretic analysis of gene expression. | Najafi A | — | 2025 | → |
| Syndrome Differentiation and Treatment of Psoriasis by Traditional Chinese Medicines: An Integrating Study of Multi-Omics Analysis and Experimental Validation. | Li C et al. | — | 2025 | → |
| Systematic benchmarking of high-throughput subcellular spatial transcriptomics platforms across human tumors. | Ren P et al. | — | 2025 | → |
| Systematic discovery of subcellular RNA patterns in the gut epithelium. | Lee M et al. | — | 2025 | → |
| Systematic identification and characterization of virus lncRNAs suggests extensive structural mimicry of host lncRNAs. | Fu P et al. | — | 2025 | → |
| Systematic mapping of small nucleolar RNA interactions in human cells. | Dunn-Davies H et al. | — | 2025 | → |
| TAPT1 interacts with SUCO to maintain the homeostasis of newly synthesized proteins and brain development in mice. | Gao J et al. | — | 2025 | → |
| Targeting angiogenesis in endometriosis: a systematic review and network meta-analysis of VEGF-directed pharmacotherapies. | Hammond O et al. | — | 2025 | → |
| Targeting ATR offers multifaceted treatment strategies involving RAD51-mediated compensatory DNA repair in bladder cancer. | Pannhausen J et al. | — | 2025 | → |
| Targeting Matrix Metalloproteinase-9 to Alleviate T Cell Exhaustion and Improve Sepsis Prognosis. | Wang X et al. | — | 2025 | → |
| Targeting triple-negative breast cancer using cord-blood CD34⁺ HSPC-derived mesothelin-specific CAR-NKT cells with potent antitumor activity. | Li YR et al. | — | 2025 | → |
| Target of rapamycin signaling in pea embryos is dependent on glutamine but detached from seed storage protein biosynthesis. | O'Leary BM et al. | — | 2025 | → |
| TaxaGO: a novel, phylogenetically informed gene ontology enrichment analysis tool. | Bochalis E et al. | — | 2025 | → |
| Tertiary lymphoid organ-associated transcriptomic features predict rejection and outcome in kidney transplantation: integrative analysis and experimental validation. | Shen X et al. | — | 2025 | → |
| TET3 protects the <i>Dlk1-Dio3</i> imprinted locus from DNA hypomethylation during adult NSC reprogramming. | Lázaro-Carot L et al. | — | 2025 | → |
| Th17-like cells and immunosuppressive macrophages infiltrate tertiary lymphoid structures with distinct maturation status in soft-tissue sarcoma. | Petroni G et al. | — | 2025 | → |
| Th1 and Th2 cells in equine endometrosis and their interactions with endometrial fibroblasts. | Wójtowicz A et al. | — | 2025 | → |
| The 13-lipoxygenase GmLOX6 is involved in JA biosynthesis and serves as a positive regulator of salt stress tolerance in soybean. | Li S et al. | — | 2025 | → |
| The B cell subtypes and VDJ repertoire of young adult rhesus macaques. | Chan AKP et al. | — | 2025 | → |
| The cancer-testis lncRNA LINC01940 promotes gastric cancer malignant progression and chemoresistance by enhancing ribosome biogenesis via TAF15-mediated NOL11 SUMOylation. | Zang W et al. | — | 2025 | → |
| The chordoid glioma <i>PRKCA</i> D463H mutation is a kinase inactive, gain-of-function allele that induces early-onset chondrosarcoma in mice. | Calleja V et al. | — | 2025 | → |
| The core genetic drivers of chronological aging in yeast are universal regulators of longevity. | Cruz-Bonilla E et al. | — | 2025 | → |
| The Distinct Monocyte Subsets and Intercellular Communication in Primary Sjögren's Syndrome Revealed by Single-Cell RNA Sequencing. | Zhang X et al. | — | 2025 | → |
| The Effects and Mechanisms of Ti-Fu-Kang Decoction in Alleviating Central Fatigue: Insights from Network Pharmacology and Metabolomics. | Zhang Y et al. | — | 2025 | → |
| The expression of genes in different sites of gut tract regulates the meat quality of semitendinosus muscle in sheep and goats. | Chen B et al. | — | 2025 | → |
| The Function of <i>RcAG2</i> and <i>RcFUL</i> in the Flower Shape Change of <i>Rosa chinensis</i> 'Viridiflora'. | Zhang J et al. | — | 2025 | → |
| The joint impact of elevated homocysteine and type 2 diabetes on non-healing wounds and all-cause mortality: integrated clinical and multi-omics analyses. | Li Y et al. | — | 2025 | → |
| The molecular architecture of severe pediatric traumatic brain injury: integrated omics reveal therapeutic pathways. | Hussain E et al. | — | 2025 | → |
| The NF-κB Signalling Regulates the Abnormal Functions of Neutrophils in Severe Periodontal Disease. | Lu W et al. | — | 2025 | → |
| The Olive Phenolic <i>S</i>-(-)-Oleocanthal as a Novel Intervention for Neuroendocrine Prostate Cancers: Therapeutic and Molecular Insights. | Tarun MTI et al. | — | 2025 | → |
| The role of SLC22A4 in Acute Myeloid Leukaemia. | Li Y et al. | — | 2025 | → |
| The whole-genome map of Astragalus mongholicus provides ideas for the synthesis of glutathione and flavonoid. | Yao M et al. | — | 2025 | → |
| Time-Series Comparative Transcriptome Analyses of Two Potato Cultivars with Different Verticillium Wilt Resistance. | Fan G et al. | — | 2025 | → |
| TIMP1 as a context-dependent biomarker linking cancer progression and cardiovascular disorders: a multi-level and bioinformatics study. | Xie H et al. | — | 2025 | → |
| Tissue-specific CLOCK isoforms modulate circadian feedback loops to govern reproductive fitness in Drosophila. | Wang Y et al. | — | 2025 | → |
| TMPRSS11B promotes an acidified microenvironment and immune suppression in squamous lung cancer. | Sunil HS et al. | — | 2025 | → |
| TMT-based quantitative proteomic assessment of Vicia sativa induced neurotoxicity by β-cyano-L-alanine and γ-glutamyl-β-cyano-L-alanine in SH-SY5Y cells. | Riley S et al. | — | 2025 | → |
| Tolerability and effect of inhibiting microfibrillar-associated protein 4 in small intestinal anastomotic healing. | Andresen RR et al. | — | 2025 | → |
| TP53-dependent antitumor effects of DHODH Inhibition in nasopharyngeal carcinoma. | Dong X et al. | — | 2025 | → |
| Transcription factor ZNF263 primes human embryonic stem cells for pluripotency dissolution and lineage commitment. | Yin Q et al. | — | 2025 | → |
| Transcriptome analysis revealed the potential molecular mechanism of style bending movement in passion fruit (Passiflora Edulis Sims). | Gao L et al. | — | 2025 | → |
| Transcriptome-Based Identification of Biomarkers Associated With Sphingosine-1-Phosphate Signaling Pathway in Aortic Dissection. | Li A et al. | — | 2025 | → |
| Transcriptome profiling across 6 different tissues in Vigna radiata var. sublobata. | Sun ZM et al. | — | 2025 | → |
| Transcriptome profiling of uterine leiomyosarcomas identifies a leiomyoma-like expression pattern that indicates better survival. | Khamaiseh S et al. | — | 2025 | → |
| Transcriptome Sequencing Reveals Distinct Stress Response of Listeria monocytogenes 6179 During Logarithmic and Stationary Growth Phases. | Strathman-Runyan JL et al. | — | 2025 | → |
| Transcriptomic analysis of ethephon-induced sex reversion of male Cannabis sativa reveals changes in expression of floral homeotic genes and a distinct trichome morphology. | Garcia-de Heer L et al. | — | 2025 | → |
| Transcriptomic Analysis of Gingival Tissues: Insights Into Gene Expression Profiles. | Reddy SSP et al. | — | 2025 | → |
| Transcriptomic dynamics of cardiac remodeling after myocardial infarction. | Sanjaya A | — | 2025 | → |
| Transcriptomic exploration combined with experimental validation: uncovering the potential value of biomarkers related to ammonia-induced cell death in hepatic ischemia-reperfusion injury. | Zhuang R et al. | — | 2025 | → |
| Transcriptomic insights into drought response in wild Arachis relatives A. dardani and A. ipaënsis. | Verma PK et al. | — | 2025 | → |
| Transcriptomic Profiles from Stereo-EEGs May Reflect the Local Brain Cell Microenvironment in Human Epilepsy. | Larkin J et al. | — | 2025 | → |
| Transcriptomic profiling of rumen epithelium, liver, and muscle reveals tissue-specific gene expression patterns in Hu sheep. | Jia X et al. | — | 2025 | → |
| Transcriptomic profiling reveals macrophage gene signatures associated with lactylation-related pathways in chronic obstructive pulmonary disease. | Guo H et al. | — | 2025 | → |
| Transcriptomic responses of beet to infection by beet mild yellowing virus. | Puthanveed V et al. | — | 2025 | → |
| Transcriptomics Analysis Reveals an Early Response Gene <i>SlNSP-like</i> Involved in <i>Solanum lycopersicum</i> Response to DC3000 Infection. | Li J et al. | — | 2025 | → |
| Transcriptomics and network pharmacology reveal the potential mechanism related to integrated stress response in the treatment of osteoporosis by Jiawei Shentong Zhuyu Decoction and verified by RT-qPCR. | Zhao J et al. | — | 2025 | → |
| Transcriptomics-based analysis of acetate and propionate transport and metabolism in Yarrowia lipolytica. | Žganjar M et al. | — | 2025 | → |
| Transcriptomics insights into the functional role of tick Ixodes ricinus proteins metalloprotease and antigen p23. | Vaz-Rodrigues R et al. | — | 2025 | → |
| Unbiased assessment of 2-arachidonoylglycerol in cardiovascular inflammation. | Nöthel M et al. | — | 2025 | → |
| Uncovering the regulatory landscape of early human B cell lymphopoiesis and its implications in the pathogenesis of B-ALL. | Planell N et al. | — | 2025 | → |
| Unraveling the Impacts of Long-Term Exposure in Low Environmental Concentrations of Antibiotics on the Growth and Development of <i>Aquatica leii</i> (Coleoptera: Lampyridae) from Transcription and Metabolism. | Li J et al. | — | 2025 | → |
| Unravelling TPX2-centered co-expression networks as key drivers of aggressive prostate cancer. | Sheibani-Tezerji R et al. | — | 2025 | → |
| Unveiling HJURP as a Biomarker of Poor Prognosis and Immunotherapy Resistance in Lung Adenocarcinoma: A Multicenter Study. | Tan Q et al. | — | 2025 | → |
| Unveiling population structure in South Pacific albacore: insights from genetics and growth. | Lu D et al. | — | 2025 | → |
| Unveiling the IL-1β/CXCL2 axis: a shared therapeutic target in periodontitis and inflammatory bowel disease. | Gu Z et al. | — | 2025 | → |
| Unveiling the role of EGR1 and hub senescence-related genes in type II alveolar epithelial cells senescence for obstructive sleep apnea. | Li CL et al. | — | 2025 | → |
| Unveiling the role of protein palmitoylation in gastric cancer diagnosis via machine learning. | Shen ZH et al. | — | 2025 | → |
| USPPAR is a cost-effective, scalable, and highly sensitive single-cell RNA sequencing workflow compatible with diverse specimens. | Hsueh YW et al. | — | 2025 | → |
| Utilising bioinformatics and molecular docking technology to explore the underlying mechanisms of intervertebral disc degeneration with potential therapeutic drugs and formulas. | Yukui T et al. | — | 2025 | → |
| Variability vs. phenotype: Multimodal analysis of Dravet syndrome brain organoids powered by deep learning. | Turpin-Moreno I et al. | — | 2025 | → |
| Vitamin D modulates gene expression in four major muscle tissues in Atlantic salmon. | Gorman CE et al. | — | 2025 | → |
| Whole-genome sequencing and analysis of the symbiotic Mycena sp. L02 with Gastrodia Elata. | Liu J et al. | — | 2025 | → |
| Whole organism integrated DNA methylation and transcriptomics analysis of butterfly metamorphosis. | Hesketh A et al. | — | 2025 | → |
| Winter Temperature Affects Fatty Acid Composition and Gene Expression, but Not Fat Content and Survival in a Northern Population of a Range-Expanding Spider. | Ortiz-Movliav C et al. | — | 2025 | → |
| ZC3HC1 has many functions distinct from TPR and is dispensable for TPR localisation to the nuclear basket. | M Bartlett B et al. | — | 2025 | → |
| Zebrafish cell lines and high-throughput transcriptomics: advancing in vitro and bioinformatics methods for supporting environmental risk assessment. | Schumann PG et al. | — | 2025 | → |
| Zinc Metalloprotease CsMep is Involved in Zinc Homeostasis and Pathogenicity in <i>Colletotrichum sublineola</i> with Alterations in Aromatic Amino Acid Biosynthesis. | Wen J et al. | — | 2025 | → |
| βcatenin-1 localization and transcriptomic profiling provide insights into the early development of planarians. | Coronel-Córdoba P et al. | — | 2025 | → |