Induction of pluripotent stem cells from adult human fibroblasts by defined factors.
- Authors
- Takahashi, Kazutoshi; Tanabe, Koji; Ohnuki, Mari; Narita, Megumi; Ichisaka, Tomoko; Tomoda, Kiichiro; Yamanaka, Shinya
- Year
- 2007
- Journal
- Cell
- PMID
- 18035408
- DOI
- 10.1016/j.cell.2007.11.019
Successful reprogramming of differentiated human somatic cells into a pluripotent state would allow creation of patient- and disease-specific stem cells. We previously reported generation of induced pluripotent stem (iPS) cells, capable of germline transmission, from mouse somatic cells by transduction of four defined transcription factors. Here, we demonstrate the generation of iPS cells from adult human dermal fibroblasts with the same four factors: Oct3/4, Sox2, Klf4, and c-Myc. Human iPS cells were similar to human embryonic stem (ES) cells in morphology, proliferation, surface antigens, gene expression, epigenetic status of pluripotent cell-specific genes, and telomerase activity. Furthermore, these cells could differentiate into cell types of the three germ layers in vitro and in teratomas. These findings demonstrate that iPS cells can be generated from adult human fibroblasts.
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| Brain Organoids and Assembloids-From Disease Modeling to Drug Discovery. | Ajongbolo AO et al. | β | 2025 | β |
| Can cell-cultured meat from stem cells pave the way for sustainable alternative protein? | Nunes OBDS et al. | β | 2025 | β |
| Cancer stem cells in personalized therapy: mechanisms, microenvironment crosstalk, and therapeutic vulnerabilities. | Yin L et al. | β | 2025 | β |
| Can Stem Cells Restore Hearing? A Narrative Review Exploring Regenerative Medicine for Congenital Hearing Loss. | Mughal A et al. | β | 2025 | β |
| Cardiac differentiation roadmap for analysis of plasticity and balanced lineage commitment. | Snabel RR et al. | β | 2025 | β |
| Cardiac repair and regeneration: cell therapy, in vivo reprogramming, and the promise of extracellular vesicles. | Karim Rony RMI et al. | β | 2025 | β |
| Categories, applications, and potential of stem cells in bone regeneration: an overview. | Jiao M et al. | β | 2025 | β |
| CDK5 Deficiency Does not Impair Neuronal Differentiation of HumanΒ Induced Pluripotent Stem Cells but Affects Neurite Outgrowth. | Mucci S et al. | β | 2025 | β |
| Cell and tissue reprogramming: Unlocking a new era in medical drug discovery. | Sen CK et al. | β | 2025 | β |
| Cell-Based Assays Using Derived Human-Induced Pluripotent Cells in Drug Discovery and Development. | Ross JA et al. | β | 2025 | β |
| Cell-based regenerative and rejuvenation strategies for treating neurodegenerative diseases. | Deng S et al. | β | 2025 | β |
| Cell-based regenerative therapy for retinal diseases: challenges and emerging bioengineering strategies. | Iwama Y et al. | β | 2025 | β |
| Cell-based therapy for diabetic cardiovascular complications: Prospects and challenges. | Li JP et al. | β | 2025 | β |
| Cell-based treatments of lung diseases: overview and outlook. | van der Does AM et al. | β | 2025 | β |
| Cell culture research in aging and Alzheimer's disease: The strategic use/reuse of untreated controls and savings people's tax dollars. | Kshirsagar S et al. | β | 2025 | β |
| CellNavi predicts genes directing cellular transitions by learning a gene graph-enhanced cell state manifold. | Wang T et al. | β | 2025 | β |
| Cell reprogramming: methods, mechanisms and applications. | Zhu F et al. | β | 2025 | β |
| Cell Reprogramming, Transdifferentiation, and Dedifferentiation Approaches for Heart Repair. | Almeida M et al. | β | 2025 | β |
| Cell therapy for liver disorders: past, present and future. | OrtuΓ±o-Costela MC et al. | β | 2025 | β |
| Cell-type-specific functionality encoded within the intrinsically disordered regions of OCT4. | Ozkan B et al. | β | 2025 | β |
| Cellular Models of Aging and Senescence. | Kim B et al. | β | 2025 | β |
| Changes in mitochondrial thymidine metabolism and mtDNA copy number during induced pluripotency. | Kim HK et al. | β | 2025 | β |
| Characterization of a Splice-Altering Variant in SCN5A Associated With Brugada Syndromeγ- Insights Into Splice Error Correction. | Jinzai H et al. | β | 2025 | β |
| Chemical reprogramming of human blood cells to pluripotent stem cells. | Peng F et al. | β | 2025 | β |
| Clinical Applications of Corneal Cells Derived from Induced Pluripotent Stem Cells. | Luan Y et al. | β | 2025 | β |
| Clinical-grade iPSC-derived chondrogenic micropellets for treating advanced cartilage defects. | Nam Y et al. | β | 2025 | β |
| Clinical state and future directions of stem cell therapy in stroke rehabilitation. | Habib P et al. | β | 2025 | β |
| Clinical translation of human iPSC technologies: advances, safety concerns, and future directions. | Dhaiban S et al. | β | 2025 | β |
| Colorectal Organoids: Models, Imaging, Omics, Therapy, Immunology, and Ethics. | Taglieri M et al. | β | 2025 | β |
| Combined Human Neural Stem Cell and Structured Treadmill Walking Therapy Enhances Recovery in a Pediatric Porcine Traumatic Brain Injury Model. | Schantz SL et al. | β | 2025 | β |
| Commercialization of Cell Therapies: A CDMO Perspective. | Baghbaderani BA | β | 2025 | β |
| Comparative analysis of dental-derived stem cells and alternative stem cell sources: properties and regenerative functions. | Yang K et al. | β | 2025 | β |
| Comparative analysis of extracellular vesicles from induced and adipose-derived Mesenchymal Stem Cells: Implications for regenerative medicine. | Nashwan S et al. | β | 2025 | β |
| Comparative analysis of transcriptomic profiles of mesenchymal stem cells at the onset of senescence and after exposure to acute exogenous oxidative stress. | Outskouni Z et al. | β | 2025 | β |
| Comparative study of CYP450 gene regulation in human pluripotent stem cell-derived liver 2D cell and 3D organoid models. | Kang E et al. | β | 2025 | β |
| Comprehensive and translational pathobiology of COVID-19 based on cellular and molecular techniques. | Samadani AA et al. | β | 2025 | β |
| Correcting tau isoform ratios with a long-acting antisense oligonucleotide alleviates 4R-tauopathy phenotypes. | Iwata-Endo K et al. | β | 2025 | β |
| Current advances and future prospects of cell reprogramming in progeroid syndromes. | Moledo-Nodar L et al. | β | 2025 | β |
| Current Applications of Human Pluripotent Stem Cells in Neuroscience Research and Cell Transplantation Therapy for Neurological Disorders. | Verma I et al. | β | 2025 | β |
| Current hPSC-derived liver organoids for toxicity testing: Cytochrome P450 enzymes and drug metabolism. | Kim H et al. | β | 2025 | β |
| Decellularized Extracellular Matrix Produced by iPSC-Derived MSCs Promotes iPSC-MSC Proliferation and Differentiation and Regulates Secreted Factors. | Huang T et al. | β | 2025 | β |
| Deciphering reprogramming efficiency in human induced pluripotent stem cells: insights from the generation of 150 cell lines. | Kuebler B et al. | β | 2025 | β |
| Deciphering the physiopathology of neurodevelopmental disorders using brain organoids. | Dionne O et al. | β | 2025 | β |
| Decoding cancer etiology with cellular reprogramming. | Huang MF et al. | β | 2025 | β |
| Decoding dental mesenchymal stem cells diversity: single-cell transcriptomics maps heterogeneity in molar development. | Zhang R et al. | β | 2025 | β |
| Decoding human chemical reprogramming: mechanisms and principles. | Cheng L et al. | β | 2025 | β |
| Defining transcription factor nucleosome binding with Pioneer-seq. | Tsompana M et al. | β | 2025 | β |
| Delivery of Human iPSC-Derived RPE Cells in Healthy Minipig Retina Results in Interaction Between Photoreceptors and Transplanted Cells. | MaceΔkovΓ‘ BrymovΓ‘ A et al. | β | 2025 | β |
| Designing multicellular cardiac tissue engineering technologies for clinical translation. | Laskary AR et al. | β | 2025 | β |
| Development and characterization of a scalable calcium imaging assay using human iPSC-derived neurons. | Haustein MD et al. | β | 2025 | β |
| Development of a cell therapy set prototype for autologous iPS cells. | Nakashima Y et al. | β | 2025 | β |
| Development of intestinal organoids and microphysiological systems and their application to drug discovery. | Iwao T et al. | β | 2025 | β |
| Development of Patient-Derived Neuroprogenitor Cells (hNPCs), Neurons and Astrocytes to Explore the Etiology of Guam Parkinsonism-Dementia Complex (PDC) | Chlebowski AC et al. | β | 2025 | β |
| Differentiation Defect Into GABAergic Neurons in Cerebral Organoids From Autism Patients. | Hali S et al. | β | 2025 | β |
| Differentiation of iPS Cells into Periodontal Ligament Cells. | Wu Y et al. | β | 2025 | β |
| Differentiation of Mature Dopaminergic Neurons from Human Induced Pluripotent Stem Cells. | Garg P et al. | β | 2025 | β |
| Differentiation of Mesenchymal Stromal/Stem Cells from Induced Pluripotent Stem Cells. | Marais AL et al. | β | 2025 | β |
| Diminished immune cell adhesion in hypoimmune ICAM-1 knockout human pluripotent stem cells. | Saha S et al. | β | 2025 | β |
| Direct in vivo reprogramming to relieve tissue ischemia via induced vasculogenesis. | Yoder MC et al. | β | 2025 | β |
| Direct reprogramming of fibroblasts into spiral ganglion neurons by defined transcription factors. | Huang Y et al. | β | 2025 | β |
| Dissecting Oct4 enhancer function in pluripotent stem cells and mouse embryogenesis. | Schmitz DA et al. | β | 2025 | β |
| Dissecting the impact of transcription factor dose on cell reprogramming heterogeneity using scTF-seq. | Liu W et al. | β | 2025 | β |
| Dual prophylactic and therapeutic potential of iPSC-based vaccines and neoantigen discovery in colorectal cancer. | Jwo SH et al. | β | 2025 | β |
| Dynamic changes of intracellular signals in ATTR Tyr114Cys amyloidosis. | Ouchi K et al. | β | 2025 | β |
| Dynamic WNT signaling controls differentiation of hematopoietic progenitor cells from human pluripotent stem cells. | Li M et al. | β | 2025 | β |
| Dysregulation of mitochondrial Ξ±-ketoglutarate dehydrogenase leads to elevated lipid peroxidation in CHCHD2-linked Parkinson's disease models. | Gao G et al. | β | 2025 | β |
| E2027 (irsenontrine), a phosphodiesterase 9 inhibitor, enhances cholinergic function when combined with donepezil hydrochloride. | Ando M et al. | β | 2025 | β |
| Early and non-destructive prediction of the differentiation efficiency of human induced pluripotent stem cells using imaging and machine learning. | Hojo MA et al. | β | 2025 | β |
| Editorial: Advancing neurodevelopmental disorder models with human iPSC and multi-omics integration. | Afshar-Saber W et al. | β | 2025 | β |
| Editorial: Induced pluripotent stem cells (iPSCs) for skeletal muscle diseases. | Sakurai H et al. | β | 2025 | β |
| Effect of iPS cell culture medium on the differentiation potential of induced cardiac tissues. | Nakashima Y et al. | β | 2025 | β |
| EIF3D safeguards the homeostasis of key signaling pathways in human primed pluripotency. | Okubo C et al. | β | 2025 | β |
| Electric-Field Nanobubble-Enhanced Progress in Anaerobic Digestion Unit Operations: Biogas Upgrading and Up- and Down-Stream Water and Sludge Treatment Operations. | English NJ | β | 2025 | β |
| Electrophysiological characterisation of intranigral-grafted hiPSC-derived dopaminergic neurons in a mouse model of Parkinson's disease. | Ballion B et al. | β | 2025 | β |
| Emerging brain organoids: 3D models to decipher, identify and revolutionize brain. | Zhao Y et al. | β | 2025 | β |
| Emerging strategies in corneal Regeneration: The role of induced pluripotent stem cell-based therapies. | Zhang H et al. | β | 2025 | β |
| Emerging trends in cell-based therapies: contemporary advances and ethical considerations in translational neurosurgical oncology. | Abikenari M et al. | β | 2025 | β |
| Endothelial cells-derived SEMA3G suppresses glioblastoma stem cells by inducing c-Myc degradation. | Min PX et al. | β | 2025 | β |
| Engineered iPSC-derived natural killer cells: recent innovations in translational innate anti-cancer immunotherapy. | Sun J et al. | β | 2025 | β |
| Engineering Characterization of Small-Scale Bioreactors for Large-Scale hiPSC Production. | Vicente P et al. | β | 2025 | β |
| Engineering Cortical Networks: An Open Platform for Controlled Human Circuit Formation and Synaptic Analysis In Vitro. | Suklai P et al. | β | 2025 | β |
| Engineering in vitro vascular microsystems. | Liu Q et al. | β | 2025 | β |
| Enhanced differentiation capacity of parthenogenetic embryonic stem cells via incorporation of non-growing oocyte genomes in mouse. | Shao H et al. | β | 2025 | β |
| Enhanced regenerative potential of human dental pulp stem cells for the pulp-dentin complex through coculture with iPSC-derived endothelial cells: An in vitro study. | Cho HM et al. | β | 2025 | β |
| Epigenetic mechanisms in stem cell therapies for achilles tendinopathy. | Yuan Z et al. | β | 2025 | β |
| Epigenetic regulatory mechanisms of autoimmune skin diseases: novel biomarkers and therapeutic prospects. | Lai X et al. | β | 2025 | β |
| Established and emerging new approach methodologies in neuroscience. | Imberechts D et al. | β | 2025 | β |
| Establishment and characterization of Cri Du Chat neuronal stem cells: a novel promising resource to study the syndrome. | Piovani G et al. | β | 2025 | β |
| Establishment of a Human iPSC Line from Mucolipidosis Type II That Expresses the Key Markers of the Disease. | Moutinho ME et al. | β | 2025 | β |
| Establishment of human Leber's hereditary optic neuropathy model using iPSC-derived retinal organoids. | Aoshima K et al. | β | 2025 | β |
| Establishment of sika deer induced pluripotent stem cellsβ . | Cao S et al. | β | 2025 | β |
| Ethical, Legal and Social Issues in Utilizing In Vitro Gametogenesis (IVG) and Stem Cell-Based Embryo Models (SCBEMs) for Human Reproduction in Singapore. | Chin AHB et al. | β | 2025 | β |
| Evaluating Strategies to Assess the Differentiation Potential of Human Pluripotent Stem Cells: A Review, Analysis and Call for Innovation. | Smith L et al. | β | 2025 | β |
| Evaluating the Response to Cryopreservation of Ovine Fibroblast Spheroids. | Piras D et al. | β | 2025 | β |
| Evidence for intermittent coupling of intramyocardial small, engineered heart tissues acutely implanted into rabbit myocardium. | Huethorst E et al. | β | 2025 | β |
| Examining patient-specific responses to PARP inhibitors in a novel, human induced pluripotent stem cell-based model of breast cancer. | Weddle CJ et al. | β | 2025 | β |
| Excessive autophagic degradation of MYLK3 causes sunitinib-induced cardiotoxicity. | Pan Z et al. | β | 2025 | β |
| Expectations regarding regenerative medicine and attitudes toward invasive surgical therapies in patients with Parkinson's disease: A cross-sectional survey. | Watabe M et al. | β | 2025 | β |
| Exploring hiPSC-CM replacement therapy in ischemic hearts. | Cipriano G et al. | β | 2025 | β |
| Exploring human brain development and disease using assembloids. | Wu SR et al. | β | 2025 | β |
| FcRn-silencing of IL-12Fc prevents toxicity of local IL-12 therapy and prolongs survival in experimental glioblastoma. | Beffinger M et al. | β | 2025 | β |
| Focused ultrasound and microbubble-mediated delivery of CRISPR-Cas9 ribonucleoprotein to human induced pluripotent stem cells. | Hazel K et al. | β | 2025 | β |
| Footprint-free induced pluripotent stem cells can be successfully differentiated into mesenchymal stromal cells in the feline model. | Weeratunga P et al. | β | 2025 | β |
| From cold chain to ambient: Benefits, risks, and evidence across cell therapy logistics. | Gostage J et al. | β | 2025 | β |
| From induced pluripotent stem cell (iPSC) to universal immune cells: literature review of advances in a new generation of tumor therapies. | Zhang J et al. | β | 2025 | β |
| From in vivo models to in vitro bioengineered neuromuscular junctions for the study of Charcot-Marie-Tooth disease. | Scherrer C et al. | β | 2025 | β |
| From Promise to Practice: Recent Growth in 30 Years of Tissue Engineering Commercialization. | Felix RB et al. | β | 2025 | β |
| From stem cells to organoids in thyroid: Useful tools or a step for cell therapy? | Kariyawasam D et al. | β | 2025 | β |
| From Stumbling Blocks to Stepping Stones: Progress in Treating Temporal Lobe Epilepsy With Stem Cell Transplantation. | Naegele JR | β | 2025 | β |
| Fully biologic endothelialized-tissue-engineered vascular conduits provide antithrombotic function and graft patency. | Park J et al. | β | 2025 | β |
| Functional Imaging Methods for Investigating 3D Choroid Plexus Organoids. | Tang SS et al. | β | 2025 | β |
| Functional Recovery by Transplantation of Human iPSC-Derived A2B5 Positive Neural Progenitor Cell After Spinal Cord Injury in Mice. | Zheng Y et al. | β | 2025 | β |
| Functional recovery through the plastic adaptation of organoid grafts in cortical tissue. | OndriΕ‘ J et al. | β | 2025 | β |
| Gastruloids enable modeling of the earliest stages of human cardiac and hepatic vascularization. | Abilez OJ et al. | β | 2025 | β |
| Gene expression profiling reveals enhanced nutrient and drug metabolism and maturation of hiPSC-derived intestine-on-chip relative to organoids and Transwells. | Moerkens R et al. | β | 2025 | β |
| Generation and Characterization of Human iPSC-Derived Astrocytes with Potential for Modeling X-Linked Adrenoleukodystrophy Phenotypes. | Kaur N et al. | β | 2025 | β |
| Generation and characterization of induced pluripotent stem cells of small apes. | Hamazaki Y et al. | β | 2025 | β |
| Generation and transcriptome profiling of bonobo induced pluripotent stem cells using stealth RNA vectors: a tripartite comparative study with humans and chimpanzees. | Hamazaki Y et al. | β | 2025 | β |
| Generation, characterization, and validation of two human induced pluripotent stem cell lines from the peripheral blood of young and older adults. | Yang D et al. | β | 2025 | β |
| Generation, interrogation, and future applications of microglia-containing brain organoids. | Di Stefano J et al. | β | 2025 | β |
| Generation of 3D Human iPSC-Derived Multi-Cell Type Neurospheres for Studying Neuron, Astrocyte, and Microglia Crosstalk. | Wendt S et al. | β | 2025 | β |
| Generation of a biallelic NRAP-knockout mutant from a human iPSC line. | Raabe J et al. | β | 2025 | β |
| Generation of a human induced pluripotent stem cell lines (UKJi003-A) from a patient with Fabry disease and healthy donor (UKJi004-A). | Bekhite MM et al. | β | 2025 | β |
| Generation of a human iPSC line, INMi007-A, carrying compound heterozygous DCT variants associated with oculocutaneous albinism type 8. | Mamaeva D et al. | β | 2025 | β |
| Generation of human induced pluripotent stem cell lines from healthy Korean donors (IPBi101-A, IPBi102-A, IPBi103-A, IPBi105-A, IPBi107-A, IPBi108-A, IPBi110-A, IPBi111-A, IPBi113-A, and IPBi114-A). | Lee M et al. | β | 2025 | β |
| Generation of hypoimmunogenic universal iPS cells through HLA-type gene knockout. | Kim J et al. | β | 2025 | β |
| Generation of Monosomy 21q Human iPS Cells by CRISPR/Cas9-Mediated Interstitial Megabase Deletion. | Egawa M et al. | β | 2025 | β |
| Genes as Genome Stabilizers in Pluripotent Stem Cells. | Karmakar A et al. | β | 2025 | β |
| Gene Therapy for Skin Aging. | Saad FA | β | 2025 | β |
| Gene therapy strategies for aging intervention. | Jing Y et al. | β | 2025 | β |
| Genome editing in spinocerebellar ataxia type 3 cells improves Golgi apparatus structure. | Wang Y et al. | β | 2025 | β |
| Genome-Wide Association Study and Genomic Prediction of Soybean Mosaic Virus Resistance. | He D et al. | β | 2025 | β |
| Global morphogenesis regulating tissue architecture and organogenesis. | Ripamonti U | β | 2025 | β |
| Global research dynamics in the induced pluripotent stem cell and diabetes: A bibliometric analysis of the past twenty years. | Wang J et al. | β | 2025 | β |
| Glycosylation in Stem Cell Biology. | Ogura C et al. | β | 2025 | β |
| GMP Manufacturing of Allogenic iPSC-NK Cells for Immunotherapy. | Zong H et al. | β | 2025 | β |
| Gold nanoclusters Au<sub>25</sub>AcCys<sub>18</sub> normalize intracellular ROS without increasing cytoplasmic alarmin acHMGB1 abundance in human microglia and neurons. | Zhang I et al. | β | 2025 | β |
| HAND2 invades nucleolar condensates to pioneer lineage-specific cardiac pacemaker gene programs. | Kulkarni K et al. | β | 2025 | β |
| Harnessing heterogeneity for the rational design of cell manufacturing. | Dorri Nokoorani Y et al. | β | 2025 | β |
| Harnessing organoid technology to model autoimmune pathways in rheumatological and inflammatory disorders. | El-Sehrawy AAMA et al. | β | 2025 | β |
| Harnessing the potential of tissue engineering to target male infertility: Insights into testicular regeneration. | Forouzandegan M et al. | β | 2025 | β |
| Hepatic organoids as a platform for liver disease modeling and the development of novel therapies. | Luce E et al. | β | 2025 | β |
| Highly efficient construction of monkey blastoid capsules from aged somatic cells. | Wu J et al. | β | 2025 | β |
| High Mobility Group A1 Chromatin Keys: Unlocking the Genome During MPN Progression. | Resar LMS et al. | β | 2025 | β |
| Host-microbiome relationship in depression: can human induced pluripotent stem cells play a role in unravelling mechanisms? | Rosell-Cardona C et al. | β | 2025 | β |
| How FAIR is metadata for human pluripotent stem cells? | Hu M et al. | β | 2025 | β |
| Human Blastoid: A Next-Generation Model for Reproductive Medicine? | Ryabchenko AS et al. | β | 2025 | β |
| Human heart-macrophage assembloids mimic immune-cardiac interactions and enable arrhythmia disease modeling. | O'Hern C et al. | β | 2025 | β |
| Human induced pluripotent stem cell-derived cardiomyocytes for disease modeling and drug discovery. | Moriwaki T et al. | β | 2025 | β |
| Human induced pluripotent stem cell-derived dopaminergic neurons release alpha-synuclein through neuronal activity. | Nuermaimaiti M et al. | β | 2025 | β |
| Human-Induced Pluripotent Stem Cell Models for Amyloid Cardiomyopathy: From Mechanistic Insights to Therapeutic Discovery. | Liu Y et al. | β | 2025 | β |
| Human induced pluripotent stem cells for in vitro modeling of impaired mucociliary clearance in cystic fibrosis lung disease. | Klassen MC et al. | β | 2025 | β |
| Human-Induced Pluripotent Stem Cells (iPSCs) for Disease Modeling and Insulin Target Cell Regeneration in the Treatment of Insulin Resistance: A Review. | Thiab S et al. | β | 2025 | β |
| Human iPSC-based breast cancer model identifies S100P-dependent cancer stemness induced by <i>BRCA1</i> mutation. | Liu J et al. | β | 2025 | β |
| Human iPSC-derived glutamatergic neurons with pathogenic KCNQ2 variants display hyperactive bursting phenotypes. | Sundberg M et al. | β | 2025 | β |
| Human iPSC-derived microglial cells protect neurons from neurodegeneration in long-term cultured adhesion brain organoids. | Chen X et al. | β | 2025 | β |
| Human iPSC Reprogramming Success: The Impact of Approaches and Source Materials. | Pozner T et al. | β | 2025 | β |
| Human kidney organoids for modeling the development of different diseases. | Ceccotti E et al. | β | 2025 | β |
| Human midbrain organoids reveal the characteristics of axonal mitochondria specific to dopaminergic neurons. | Nishijima A et al. | β | 2025 | β |
| Human organoids and organ-on-chips in coeliac disease research. | Simpson HL et al. | β | 2025 | β |
| Human Pluripotent Stem Cell-Based Therapies for Parkinson's Disease: Challenges and Potential Solutions. | Chang MY et al. | β | 2025 | β |
| Human pluripotent stem cell-derived intestinal organoids for pharmacokinetic studies. | Saito T et al. | β | 2025 | β |
| Human PSC-derived liver cells and their applications for disease models and drug discovery. | Koui Y et al. | β | 2025 | β |
| Human Stem Cells in Disease Modelling and Treatment: Bridging the Gap Between Bench and Bedside. | Plaza Reyes A et al. | β | 2025 | β |
| Hydrogels for Cardiac Tissue Regeneration: Current and Future Developments. | Holme S et al. | β | 2025 | β |
| Identification of ZNF850 as a novel CTG repeat expansion-related gene in myotonic dystrophy type 1 patient-derived iPSCs. | Kamon M et al. | β | 2025 | β |
| Imaging technology in tracking the intravital fate of transplanted stem cells. | Shen L et al. | β | 2025 | β |
| <i>MAPT</i>-A152T mutation drives neuronal hyperactivity through Fyn-NMDAR signaling in human iPSC-Derived neurons: Insights into Alzheimer's pathogenesis. | Itsuno M et al. | β | 2025 | β |
| Immune and Immune-Integrated Organoids as NextGeneration Platforms for Disease Modeling. | Rashidan K et al. | β | 2025 | β |
| Impact of circadian rhythm on differentiation and maturation of insulin-producing cells. | Moon JE et al. | β | 2025 | β |
| Impact of Mitochondrial A3243G Mutation on Skeletal Muscle Energy Metabolism: Evidence from Human Induced Pluripotent Stem Cell-Derived Skeletal Muscle Cells. | Oikawa R et al. | β | 2025 | β |
| Impaired synaptosome phagocytosis in macrophages of individuals with autism spectrum disorder. | Nishi Y et al. | β | 2025 | β |
| Incisional choroidal surgery. | Mano F et al. | β | 2025 | β |
| Increasing hexokinase 1 expression improves mitochondrial and glycolytic functional deficits seen in sporadic Alzheimer's disease astrocytes. | Bell SM et al. | β | 2025 | β |
| Induced Pluripotent (iPSC) and Mesenchymal (MSC) Stem Cells for In Vitro Disease Modeling and Regenerative Medicine. | Panferov E et al. | β | 2025 | β |
| Induced pluripotent stem cell-derived cardiomyocyte in vitro models: benchmarking progress and ongoing challenges. | Ewoldt JK et al. | β | 2025 | β |
| Induced pluripotent stem cell-derived macrophages as a platform for modelling human disease. | Tiwari SK et al. | β | 2025 | β |
| Induced pluripotent stem cell-derived mesenchymal stem cells for modeling and treating metabolic associated fatty liver disease and metabolic associated steatohepatitis: Challenges and opportunities. | Silva B et al. | β | 2025 | β |
| Induced pluripotent stem cell-derived stellate cells promote proliferation of induced pluripotent stem cell-derived hepatocytes through the mitogen-activated protein kinase pathway via hepatocyte growth factor. | Tomiyama T et al. | β | 2025 | β |
| Induced Pluripotent Stem Cells-Based Regenerative Therapies in Treating Human Aging-Related Functional Decline and Diseases. | Yu P et al. | β | 2025 | β |
| Induced Pluripotent Stem Cells Derived Cellular Models for Investigating Parkinson's Disease Pathogenesis and Drug Screening. | Liu J et al. | β | 2025 | β |
| Induced Pluripotent Stem Cells for the Treatment of Lysosomal Storage Disorders. | Lorino M et al. | β | 2025 | β |
| Induced Pluripotent Stem Cells in Cardiomyopathy: Advancing Disease Modeling, Therapeutic Development, and Regenerative Therapy. | Vo QD et al. | β | 2025 | β |
| Induced Pluripotent Stem Cells in Congenital Long QT Syndrome: Research Progress and Clinical Applications. | Li Q et al. | β | 2025 | β |
| Inducible pluripotent stem cell models to study bone marrow failure and MDS predisposition syndromes. | Sahoo SS et al. | β | 2025 | β |
| Inducing Oxidative Stress-Driven Senescent Phenotype in Induced Pluripotent Stem Cell Derived Cardiomyocytes. | Emanet H et al. | β | 2025 | β |
| Induction of feline fetal fibroblasts into pluripotent stem cells using cat-derived reprogramming factors. | Qin J et al. | β | 2025 | β |
| Inhibition of ceramide synthesis improves the outcome of ischemia/reperfusion injury in cardiomyocytes derived from human induced pluripotent stem cell. | Haxhikadrija P et al. | β | 2025 | β |
| Inhibition of N-myristoyltransferase in pluripotent stem cells promotes the naive state in mice and elicits trophectoderm and primitive endoderm markers in humans. | Yoshida J et al. | β | 2025 | β |
| Inhibition of PRC2 enables self-renewal of blastoid-competent naive pluripotent stem cells from chimpanzee. | Huang T et al. | β | 2025 | β |
| Inhibition of TGF-Ξ² signaling enhances osteogenic potential of iPSC-derived MSCs. | Umrath F et al. | β | 2025 | β |
| Integrating allostasis and emerging technologies to study complex diseases. | Park I et al. | β | 2025 | β |
| Integrative Proteomics and Genomics Identify Novel Biomarkers and Therapeutic Targets in Vitiligo via Mendelian Randomization. | Yan C et al. | β | 2025 | β |
| Integrin Ξ²1 activity controls colony morphology during human pluripotent stem cell state transitions. | Taskinen ME et al. | β | 2025 | β |
| Intercellular mRNA transfer alters the human pluripotent stem cell state. | Yoneyama Y et al. | β | 2025 | β |
| Interplay Between KLF4, STAT, IRF, and NF-ΞΊB in VSMC and Macrophage Plasticity During Vascular Inflammation and Atherosclerosis. | Lopacinska N et al. | β | 2025 | β |
| Interplay between pioneer transcription factors and epigenetic modifiers in cell reprogramming. | Mirizio G et al. | β | 2025 | β |
| Intestinal organoids: The path towards clinical application. | Sugihara HY et al. | β | 2025 | β |
| Investigating the ageing-Parkinson's disease nexus: standardisation of in vitro models and techniques by the PD-AGE network. | Bury AG et al. | β | 2025 | β |
| Investigational agents for ischaemic cardiomyopathy treatment: preclinical and early phase insights. | Ossola P et al. | β | 2025 | β |
| In vitro and ex vivo models of the oral mucosa as platforms for the validation of novel drug delivery systems. | Macartney RA et al. | β | 2025 | β |
| In Vitro Evaluation of Exon Skipping in Disease-Specific iPSC-Derived Myocytes. | Sakurai H | β | 2025 | β |
| In vitro generation of a ureteral organoid from pluripotent stem cells. | Ibi Y et al. | β | 2025 | β |
| In vitro liver models for toxicological research. | Fukunaga I et al. | β | 2025 | β |
| In vitro modeling of cell types in cardiogenesis and congenital heart disease. | Ranade SS | β | 2025 | β |
| In Vitro Skin Models as Non-Animal Methods for Dermal Drug Development and Safety Assessment. | Costa Gagosian VS et al. | β | 2025 | β |
| In Vivo Reprogramming Highlights Epigenetic Regulation That Shapes Cancer Hallmarks. | Yamada Y et al. | β | 2025 | β |
| iPSC-based cell replacement therapy: from basic research to clinical application. | Takahashi J | β | 2025 | β |
| iPSC-derived macrophages: An in vitro model to study human disease-relevant macrophage biology. | Sauer J et al. | β | 2025 | β |
| iPSC-derived retinal pigment epithelium: an in vitro platform to reproduce key cellular phenotypes and pathophysiology of retinal degenerative diseases. | Li H et al. | β | 2025 | β |
| [iPS cell-based therapy for muscular disorders]. | Sakurai H | β | 2025 | β |
| iPSCs and iPSC-derived cells as a model of human genetic and epigenetic variation. | Quaid K et al. | β | 2025 | β |
| Islet Cell Replacement and Regeneration for Type 1 Diabetes: Current Developments and Future Prospects. | Rech Tondin A et al. | β | 2025 | β |
| Isolation and characterization of bovine Limbal mesenchymal stromal cells for application in ocular toxicity studies. | Benedetti MD et al. | β | 2025 | β |
| <i>SPRR1A</i> is a potential therapeutic target for osteosarcoma: <i>in vitro</i> and <i>in vivo</i> evaluations using generated artificial osteosarcoma cancer stem cellβlike cells. | Miyamoto T et al. | β | 2025 | β |
| KLF7 is a general inducer of human pluripotency. | Arboit M et al. | β | 2025 | β |
| KRIT1 heterozygous mutations are sufficient to induce a pathological phenotype in patient-derived iPSC models of cerebral cavernous malformation. | Arce M et al. | β | 2025 | β |
| Laminin-511-functionalized fibrin gel enables in-gel proliferation of human induced pluripotent stem cells. | Taniguchi Y et al. | β | 2025 | β |
| Large-Scale Production of Transfusion-Ready Red Blood Cells From Induced Pluripotent Stem Cells. | Varga E et al. | β | 2025 | β |
| LEC2 induces somatic cell reprogramming through epigenetic activation of plant cell totipotency regulators. | Peng J et al. | β | 2025 | β |
| LMNA-related cardiomyopathy: From molecular pathology to cardiac gene therapy. | Wang Z et al. | β | 2025 | β |
| Long-term culture and passaging of term trophoblast for the investigation of syncytiotrophoblast function. | Hawkins A et al. | β | 2025 | β |
| Long-term culture of chicken tracheal organoids for the purpose of avian influenza virus research. | de Bruin ACM et al. | β | 2025 | β |
| Long-term engrafting multilineage hematopoietic cells differentiated from human induced pluripotent stem cells. | Ng ES et al. | β | 2025 | β |
| Loss of cadherin 17 downregulates LGR5 expression, stem cell properties and drug resistance in metastatic colorectal cancer cells. | BartolomΓ© RA et al. | β | 2025 | β |
| LRRK2 G2019S mutation contributes to mitochondrial transfer dysfunction in a Drp1-STX17-dependent manner. | Ding M et al. | β | 2025 | β |
| <i>In silico</i> analysis of <i>UCP</i> promoters predicts conserved and human specific regulators of adipocyte thermogenesis. | TΓ³th BB et al. | β | 2025 | β |
| <i>In vitro</i> derivation of megakaryocytes and platelets from induced pluripotent stem cells: developmental foundations and translational perspectives. | Mazurek M et al. | β | 2025 | β |
| LXR agonist rescues synaptic dysfunction and degeneration in SPG3A patient-specific iPSC-derived neurons. | Thakur G et al. | β | 2025 | β |
| Machine-guided cell-fate engineering. | Appleton E et al. | β | 2025 | β |
| Macrophage Containing Cardiac Organoids for Studying Inflammatory Programmes Driving Cardiovascular Disease. | Hunter CR et al. | β | 2025 | β |
| Magnetically reshapable 3D multi-electrode arrays of liquid metals for electrophysiological analysis of brain organoids. | Kim E et al. | β | 2025 | β |
| Mammalian Blastema: Possibility and Potentials. | Nam J et al. | β | 2025 | β |
| Mass Production of Uniform Embryoid Bodies by Acoustic Standing Waves. | Hahn J et al. | β | 2025 | β |
| Material surface conjugated with fibroblast growth factor-2 for pluripotent stem cell culture and differentiation. | Sung TC et al. | β | 2025 | β |
| Maternal Ξ±-casein deficiency extends the lifespan of offspring and programmes their body composition. | Kolb AF et al. | β | 2025 | β |
| MDM4 enables efficient human iPS cell generation from PBMCs using synthetic RNAs. | Nakagawa M et al. | β | 2025 | β |
| Mesenchymal stem cells derived from hPSC via neural crest attenuate chemotherapy-induced premature ovarian insufficiency by ameliorating apoptosis and oxidative stress in granulosa cells. | Li X et al. | β | 2025 | β |
| Mesenchymal stem cell therapy for end-stage liver disease: adversity and opportunity. | Li S et al. | β | 2025 | β |
| Metabolic activities are selective modulators for individual segmentation clock processes. | Matsuda M et al. | β | 2025 | β |
| Metabolic Culture Medium Enhances Maturation of Human iPSC-Derived Cardiomyocytes via Cardiac Troponin I Isoform Induction. | Goliusova DV et al. | β | 2025 | β |
| Metabolic Maturation in hiPSC-Derived Cardiomyocytes: Emerging Strategies for Inducing the Adult Cardiac Phenotype. | Malan D et al. | β | 2025 | β |
| Metformin Protects Human Induced Pluripotent Stem Cell (hiPSC)-Derived Neurons from Oxidative Damage Through Antioxidant Mechanisms. | Gharandouq MH et al. | β | 2025 | β |
| Methods for Pluripotent Stem Cell Characterization: A Narrative Review. | Temsamani F et al. | β | 2025 | β |
| MFGE8 Acts as a Cell Adhesion Factor for Human-Induced Pluripotent Stem Cells in Embryology. | Nakashima Y et al. | β | 2025 | β |
| Microelectrode arrays cultured with in vitro neural networks for motion control tasks: encoding and decoding progress and advances. | Hua S et al. | β | 2025 | β |
| Microglia depletion reduces human neuronal APOE4-related pathologies in a chimeric Alzheimer's disease model. | Rao A et al. | β | 2025 | β |
| miR-199a functions downstream of MeCP2 in neurons of <i>MECP2</i> duplication syndrome models. | Akaba Y et al. | β | 2025 | β |
| Mitochondria and pluripotency: from established models to emerging roles in adult stem cells. | Labusca L et al. | β | 2025 | β |
| Mitochondrial Amount Determines Doxorubicin-Induced Cardiotoxicity in Cardiomyocytes. | Xiong W et al. | β | 2025 | β |
| MIXL1 activation in endoderm differentiation of human induced pluripotent stem cells. | Osteil P et al. | β | 2025 | β |
| Modeling ALS with Patient-Derived iPSCs: Recent Advances and Future Potentials. | Dawoody Nejad L et al. | β | 2025 | β |
| Modeling Alzheimer's Disease: A Review of Gene-Modified and Induced Animal Models, Complex Cell Culture Models, and Computational Modeling. | Timofeeva AM et al. | β | 2025 | β |
| Modeling antithymocyte globulin-induced microvasculopathy using human iPSC-derived vascularized liver organoids. | Kawamura S et al. | β | 2025 | β |
| Modeling combinatorial regulation from single-cell multi-omics provides regulatory units underpinning cell type landscape using cRegulon. | Feng Z et al. | β | 2025 | β |
| Modeling neurodegenerative diseases with brain organoids: from development to disease applications. | Larriba-GonzΓ‘lez T et al. | β | 2025 | β |
| Modeling of T cell-mediated autoimmune pituitary disease using human induced pluripotent stem cell-originated organoid. | Kanie K et al. | β | 2025 | β |
| Modeling the Effect of Cannabinoid Exposure During Human Neurodevelopment Using Bidimensional and Tridimensional Cultures. | Estudillo E et al. | β | 2025 | β |
| Model Systems of Chronic Kidney Disease: A Detailed Overview and Recent Advances. | Lahane GP et al. | β | 2025 | β |
| Modulation of the JAK2-STAT3 pathway promotes expansion and maturation of human iPSC-derived myogenic progenitor cells. | Caputo L et al. | β | 2025 | β |
| Molecular and cellular neurocardiology in heart disease. | Habecker BA et al. | β | 2025 | β |
| Molecular basis of cell fate plasticity - insights from the privileged cells. | Scalf SM et al. | β | 2025 | β |
| MorPhiC Consortium: towards functional characterization of all human genes. | Adli M et al. | β | 2025 | β |
| Mouse Embryonic Fibroblasts Reprogramming to Induced Pluripotent Stem Cells by T3. | Montero-Pedrazuela A et al. | β | 2025 | β |
| Mpox virus replicates in lung organoids without significantly affecting their cellular function. | Nakata Y et al. | β | 2025 | β |
| Multilayered Freestanding Porous Polycarbonate Nanosheets with Directed Protein Permeability for Cell-Encapsulated Devices. | Zushi N et al. | β | 2025 | β |
| Multilineage potential induced by reconstruction of three-dimensional structures in mouse fetal brain cells. | Ohnishi K et al. | β | 2025 | β |
| Multi-phoretic nanomotor with consistent motion direction for enhanced cancer therapy. | Zhang W et al. | β | 2025 | β |
| Multiplexed iPSC platform for advanced NK cell immunotherapies. | Kumar A et al. | β | 2025 | β |
| Musculoskeletal Organs-on-Chips: An Emerging Platform for Studying the Nanotechnology-Biology Interface. | Wang Y et al. | β | 2025 | β |
| Myotonic dystrophy type 1: clinical diversity, molecular insights and therapeutic perspectives. | Rahm L et al. | β | 2025 | β |
| Nanosensor-based imaging of realtime dopamine release in neurons derived from iPSCs of patients with Parkinson's disease. | Lee N et al. | β | 2025 | β |
| Nav1.8 and Chronic Pain: From Laboratory Animals to Clinical Patients. | Xie YF | β | 2025 | β |
| Navigating the Autophagy Maze: ATG and Their Impact on Neurodegenerative Diseases. | Amirian R et al. | β | 2025 | β |
| NEUROD1 efficiently converts peripheral blood cells into neurons with partial reprogramming by pluripotency factors. | Saito Y et al. | β | 2025 | β |
| Neurogenin 2-induced central neurons generated from NPC patient-derived iPSC display attenuated neurite outgrowth while accumulating cholesterol. | Igarashi M et al. | β | 2025 | β |
| Next-Gen Therapeutics: Pioneering Drug Discovery with iPSCs, Genomics, AI, and Clinical Trials in a Dish. | Yildirim Z et al. | β | 2025 | β |
| NN15-017 promotes human pluripotent stem cell proliferation and generation. | Fujigaki-Yamazaki S et al. | β | 2025 | β |
| (Non)canonical Wnt signaling, cytoarchitecture and stemness: new insights from primary nonmetastatic, primary metastatic, regional and distant metastatic models of adrenocortical carcinoma. | Shapiro I et al. | β | 2025 | β |
| Noncoding RNA and Alcohol Use Disorder: A Scoping Review of Current Research and Knowledge Gaps. | Upreti D et al. | β | 2025 | β |
| Non-viral derivation of induced pluripotent stem cells from the canine umbilical cord. | Yamazaki A et al. | β | 2025 | β |
| Optimized, Efficient Measurement of the Expression of Undifferentiated Stem Cell Markers in Human Induced Pluripotent Stem Cells (iPSCs) by Flow Cytometry. | Saware V et al. | β | 2025 | β |
| Optimized Method to Generate Well-Characterized Macrophages from Induced Pluripotent Stem Cells. | Hai Q et al. | β | 2025 | β |
| Organoid-based tissue engineering for advanced tissue repair and reconstruction. | Hsiung N et al. | β | 2025 | β |
| Organoids as predictive platforms: advancing disease modeling, therapeutic innovation, and drug delivery systems. | Huang T et al. | β | 2025 | β |
| Origin of chromosome 12 trisomy surge in human induced pluripotent stem cells. | Narozna M et al. | β | 2025 | β |
| Parsing Glomerular and Tubular Structure Variability in High-Throughput Kidney Organoid Culture. | Uusi-Rauva K et al. | β | 2025 | β |
| PAX6-dependent differentiation landscape of ocular surface epithelium via single-cell RNA sequencing in hiPSC-derived ocular developmental organoid. | Kamuro R et al. | β | 2025 | β |
| Pharmacological and toxicological roles of Kruppel-like factors (KLFs) in the cardiovascular system: a review. | Zhao X et al. | β | 2025 | β |
| PKD1 mutation perturbs morphogenesis in tubular epithelial organoids derived from human pluripotent stem cells. | Scarlat A et al. | β | 2025 | β |
| Plasma Membrane Lipid Composition and Turnover in Human Midbrain Neurons Investigated by Time-of-Flight Mass Spectrometry. | Berlin E et al. | β | 2025 | β |
| Pluripotency genes of mammals: a network at work. | Cancedda R et al. | β | 2025 | β |
| Pluripotent Cells Expressing APOE4 Exhibit a Pronounced Pro-Apoptotic Phenotype Accompanied by Markers of Hyperinflammation and a Blunted NF-ΞΊB Response. | Schulten W et al. | β | 2025 | β |
| Pluripotent stem cell-based approaches for heart repair and the potential of genetic modifications. | Dulak J et al. | β | 2025 | β |
| Pluripotent stem cell-derived gametes: A gap for infertility treatment and reproductive medicine in the future. | Shafiei G et al. | β | 2025 | β |
| Pluripotent stem-cell-derived therapies in clinical trial: A 2025 update. | Kirkeby A et al. | β | 2025 | β |
| Poly(ADP-ribose) polymerase-1 (PARP1)-based dual inhibitors targeting cancer synthetic lethality (2022-present): advances and perspectives. | Ye GW et al. | β | 2025 | β |
| Precision medicine approach for in vitro modeling and computational screening of anti-epileptic drugs in pediatric epilepsy patients with SCN2A (R1629L) mutation. | Kim J et al. | β | 2025 | β |
| Preclinical biodistribution and safety evaluation of human iPSC-derived dopaminergic neural progenitor cells for Parkinson's disease. | Huang Y et al. | β | 2025 | β |
| Preclinical Evaluation and Advancements in Vascularized Bone Tissue Engineering. | Kawai T | β | 2025 | β |
| Prediction of the hypothalamus-pituitary organoid formation using machine learning. | Matsumoto R et al. | β | 2025 | β |
| Preservation of ovarian function using human pluripotent stem cell-derived mesenchymal progenitor cells. | Lee DR et al. | β | 2025 | β |
| Primitive means first, not worst: Critical roles for primitive endoderm in embryos and embryo models. | Shammami MA et al. | β | 2025 | β |
| Production of bioactive cytokines using plant expression system for cardiovascular cell differentiation from human pluripotent stem cells. | Murata K et al. | β | 2025 | β |
| Progress in engineering functional cardiac tissues from iPSC-derived cardiomyocytes: advances in construction and applications. | Huang M et al. | β | 2025 | β |
| Progression of differentiation of iPSCs into specific subtypes of neurons. | Wang J et al. | β | 2025 | β |
| Progress Toward Genetic Rescue of the Northern White Rhinoceros (<i>Ceratotherium simum cottoni</i>). | Korody ML et al. | β | 2025 | β |
| Prokaryotic Expression and Purification of the hSox2-HMG Domain. | Yang L et al. | β | 2025 | β |
| Promising tools for future drug discovery and development in antiarrhythmic therapy. | MondΓ©jar-ParreΓ±o G et al. | β | 2025 | β |
| Promoting the adoption of best practices and standards to enhance quality and reproducibility of stem cell research. | Selfa Aspiroz L et al. | β | 2025 | β |
| Prospects of induced pluripotent stem cells in treating advancing Alzheimer's disease: A review. | Park JJ et al. | β | 2025 | β |
| Proteogenomic reprogramming to a functional human blastomere-like stem cell state via a PARP-DUX4 regulatory axis. | Zimmerlin L et al. | β | 2025 | β |
| Proteomics of Duchenne Muscular Dystrophy Patient iPSC-Derived Skeletal Muscle Cells Reveal Differential Expression of Cytoskeletal and Extracellular Matrix Proteins. | Gallert SM et al. | β | 2025 | β |
| Protocol for in vitro phagocytosis assay for primary mouse microglia and human embryonic stem cell-derived microglia. | Zhu B et al. | β | 2025 | β |
| Protocol for production of homogeneous iPSC spheroids and microtissues using the suction technique. | Moriwaki T et al. | β | 2025 | β |
| Protocol for the induction of human spinal motor neurons from human induced pluripotent stem cells for studying amyotrophic lateral sclerosis. | Setsu S et al. | β | 2025 | β |
| Pulsed electromagnetic stimulation promotes neuronal maturation by up-regulating cholesterol biosynthesis. | Chen P et al. | β | 2025 | β |
| Quasi-spatial single-cell transcriptome based on physical tissue properties defines early aging associated niche in liver. | Tak KY et al. | β | 2025 | β |
| Quick and robust method for the generation of human iPSC-derived choroid plexus organoids. | Kado Abdalkader R et al. | β | 2025 | β |
| Rapid generation of functional vascular organoids via simultaneous transcription factor activation of endothelial and mural lineages. | Gong L et al. | β | 2025 | β |
| Real-Time, Continuous Monitoring of Tissue Chips as an Emerging Opportunity for Biosensing. | Cognetti JS et al. | β | 2025 | β |
| Recellularization of decellularized vascular grafts via aligned seeding of endothelial cells derived from human iPS cells. | Kobayashi M et al. | β | 2025 | β |
| Recent Advances of Pluripotent Stem Cell-Derived Cardiomyocytes for Regenerative Medicine. | Ibrahim FM et al. | β | 2025 | β |
| Regenerating Locus Coeruleus-Norepinephrine (LC-NE) Function: A Novel Approach for Neurodegenerative Diseases. | Yang Y et al. | β | 2025 | β |
| Regenerative Immunotherapy for Cancer: Transcription Factor Reprogramming of Tumor-Specific T Cells. | McCaw TR et al. | β | 2025 | β |
| Regional Gene Therapy for Bone Tissue Engineering: A Current Concepts Review. | Gallo MC et al. | β | 2025 | β |
| Remodeling of cytoskeleton, chromatin, and gene expression during mechanical rejuvenation of aged human dermal fibroblasts. | Sornapudi TR et al. | β | 2025 | β |
| Remodeling of tumor microenvironment by cellular senescence and immunosenescence in cervical cancer. | He Y et al. | β | 2025 | β |
| Rescue of imprinted genes by epigenome editing in human cellular models of Prader-Willi syndrome. | Nemoto A et al. | β | 2025 | β |
| Research of <i>inΒ vivo</i> reprogramming toward clinical applications in regenerative medicine: A concise review. | Nakatsukasa Y et al. | β | 2025 | β |
| Retention of locally injected human iPS cell-derived cardiomyocytes into the myocardium using hydrolyzed gelatin. | Iida J et al. | β | 2025 | β |
| Revitalizing the Epigenome of Adult Jaw Periosteal Cells: Enhancing Diversity in iPSC-Derived Mesenchymal Stem Cells (iMSCs). | Umrath F et al. | β | 2025 | β |
| Revolutionising Cardio-Oncology Care with Precision Genomics. | Chong JH et al. | β | 2025 | β |
| Rewiring the seizing brain: stem cell grafts as neuromodulatory architects in epilepsy therapy. | Wang Z et al. | β | 2025 | β |
| RNA m<sup>6</sup>A dynamics promote transcription and RNA stability of bivalent genes during iPSC-induced generation of human lung progenitors. | Dong S et al. | β | 2025 | β |
| Robust, scalable and xeno-free protocol for differentiating human induced pluripotent stem cells into functional macrophages. | De Homdedeu M et al. | β | 2025 | β |
| Scaffold-free cell sheet therapies: clinical advances, global approval landscapes, and strategic directions to address regenerative medicine barriers. | Lin A et al. | β | 2025 | β |
| Scalable Bioelectronic Production of Extracellular Vesicles for Cardiac Tissue Regeneration. | Meng L et al. | β | 2025 | β |
| Selection of optimal human myoblasts based on patient related factors influencing proliferation and differentiation capacity. | Englich M et al. | β | 2025 | β |
| Serine synthesis pathway regulates cardiac differentiation from human pluripotent stem cells. | Umei TC et al. | β | 2025 | β |
| Signaling pathway-based culture condition improves differentiation potential of canine induced pluripotent stem cells. | Nishimura T et al. | β | 2025 | β |
| Simultaneous optical recording of action potentials and calcium transients in cardiac single cells differentiated from type 1 CPVT-iPS cells. | Takaki T et al. | β | 2025 | β |
| Single-cell sequencing and organoids: applications in organ development and disease. | Li T et al. | β | 2025 | β |
| Small cell carcinoma of the bladder: Review of pathogenesis, presentation, and management. | Simon NI et al. | β | 2025 | β |
| Small-diameter artery grafts engineered from pluripotent stem cells maintain 100% patency in an allogeneic rhesus macaque model. | Zhang J et al. | β | 2025 | β |
| Small peptide P110 mitigates axonal degeneration of SPG15 patient iPSC-derived neurons by targeting mitochondrial dysfunction. | Tamilselvam B et al. | β | 2025 | β |
| SNAP-25: A biomarker of synaptic loss in neurodegeneration. | Zhang C et al. | β | 2025 | β |
| Somatic and Stem Cell Bank to study the contribution of African ancestry to dementia: African iPSC Initiative. | Maina MB et al. | β | 2025 | β |
| Somatic cell reprogramming from different origins and donors into iPSC, with four factors OSKM using viral Sendai vectors. | Desprat R et al. | β | 2025 | β |
| Sox2 interacts with Atoh1 and Huwe1 loci to regulate Atoh1 transcription and stability during hair cell differentiation. | Cheng YF et al. | β | 2025 | β |
| SPP1 regulates tumor progression through modulation of signaling pathways and the tumor microenvironment. | Feng Y et al. | β | 2025 | β |
| State-of-the-Art: Somatic Cell Sources Used for the Generation of Human Induced Pluripotent Stem Cells. | Klingenstein S et al. | β | 2025 | β |
| Stem cell-based embryo models: a tool to study early human development. | Wu B et al. | β | 2025 | β |
| Stem cell-derived gametes: what to expect when expecting their clinical introduction. | de Bruin IJ et al. | β | 2025 | β |
| Stem Cells and Organoids: A Paradigm Shift in Preclinical Models Toward Personalized Medicine. | Luce E et al. | β | 2025 | β |
| Stem Cells Reprogramming in Diabetes Mellitus and Diabetic Complications: Recent Advances. | Madkor HR et al. | β | 2025 | β |
| Stem cell therapies for diabetes. | Chen JT et al. | β | 2025 | β |
| Stem cell therapy: a revolutionary cure or a pandora's box. | Marei HE | β | 2025 | β |
| Stem Cell Therapy for Diseases of Livestock Animals: An In-Depth Review. | Narasimha RB et al. | β | 2025 | β |
| Stem cell therapy for Parkinson's disease: A new hope for neural regeneration. | Mokhtari YG et al. | β | 2025 | β |
| Strategies to Develop Regenerative Medicine Approaches for Olfactory Disorders. | Kim DH et al. | β | 2025 | β |
| Strengthening Rigor and Reproducibility in Epigenome-Wide Association Studies of Social Exposures and Brain-Based Health Outcomes. | McKenna BG et al. | β | 2025 | β |
| Structural Analysis of Cerebral Organoids Using Confocal Microscopy and Transmission/Scanning Electron Microscopy. | Noh S et al. | β | 2025 | β |
| Supramolecular Additive Screening to Engineer Microfibrous Rafts for Expansion of Pluripotent Stem Cells in Dynamic Suspension. | van Sprang JF et al. | β | 2025 | β |
| Swift induction of human spinal lower motor neurons and robust ALS cell screening via single-cell imaging. | Setsu S et al. | β | 2025 | β |
| Synthetic and Tissue-Engineered Vascular Grafts: Current Status, Emerging Technologies, and Clinical Prospects. | Gong K et al. | β | 2025 | β |
| Targeted Cancer Stem Cell Therapeutics: An Update. | Fatima N et al. | β | 2025 | β |
| Targeted partial reprogramming as a novel therapeutic strategy for age-related decline. | Rose M et al. | β | 2025 | β |
| Target neutrophil heterogeneity and plasticity in cancer. | Feng Y et al. | β | 2025 | β |
| Telomerase dynamics in stem cells: Unraveling the molecular nexus of cellular aging and regeneration. | Jiang Y et al. | β | 2025 | β |
| Telomeres as hallmarks of iPSC aging: A review on telomere dynamics during stemness and cellular reprogramming. | Tavares-Marcos C et al. | β | 2025 | β |
| Tfcp2l1 as a central integrator of hypoxia, dedifferentiation, and tumor progression. | Clemente-GonzΓ‘lez C et al. | β | 2025 | β |
| The clinical landscape of CAR NK cells. | JΓΈrgensen LV et al. | β | 2025 | β |
| The Emerging Role of Peroxisome Proliferator-Activated Receptors in Cancer Stemness. | Parejo-Alonso B et al. | β | 2025 | β |
| The Evolution of Cell Culture Systems to Study Hepatitis B Virus Pathogenesis and Antiviral Susceptibility. | Sibiya T et al. | β | 2025 | β |
| The future of embryo engineering and fertility research in interdisciplinary collaboration. | SoczyΕska J et al. | β | 2025 | β |
| The Generation of Two Induced Pluripotent Cell Lines from Patients with an Atypical Familial Form of Lung Fibrosis. | Al-Mutairy E et al. | β | 2025 | β |
| The Golden Age of Cell and Gene Therapy. | Horwitz EM | β | 2025 | β |
| The important role of the Wnt/Ξ²-catenin signaling pathway in small molecules mediated gingival mesenchymal stem cells transdifferentiate into neuron-like cells. | Liang Q et al. | β | 2025 | β |
| The isoflavone puerarin promotes generation of human iPSC-derived pre-oligodendrocytes and enhances endogenous remyelination in rodent models. | Xu H et al. | β | 2025 | β |
| The landscape of cell lineage tracing. | Feng Y et al. | β | 2025 | β |
| The Low Tumorigenic Risk and Subtypes of Cardiomyocytes Derived from Human-induced Pluripotent Stem Cells. | Lu J et al. | β | 2025 | β |
| The modeling of human implantation and early placentation: achievements and perspectives. | Dimova T et al. | β | 2025 | β |
| The Multifaceted Roles of Zinc Finger Proteins in Pluripotency and Reprogramming. | Qian Y et al. | β | 2025 | β |
| The next generation of regenerative dentistry: From tooth development biology to periodontal tissue, dental pulp, and whole tooth reconstruction in the clinical setting. | Morita K et al. | β | 2025 | β |
| The novel combination of small-molecule inhibitors increases the survival and colony formation capacity of human induced pluripotent stem cells after single-cell dissociation. | Laowtammathron C et al. | β | 2025 | β |
| The paradoxical role of stem cells in osteosarcoma: from pathogenesis to therapeutic breakthroughs. | Su Z et al. | β | 2025 | β |
| The Past, Present, and Future Development of Cell Culture Substrates for PSC-Derived Therapies and the Challenges in Meeting the Plethora of Emerging User Requirements. | Kele M et al. | β | 2025 | β |
| Therapeutic potential of stem cell-derived somatic cells to treat metabolic dysfunction-associated steatotic liver disease and diabetes. | Gilglioni EH et al. | β | 2025 | β |
| The Rapid Activation of MYDGF Is Critical for Cell Survival in the Acute Phase of Retinal Regeneration in Fish. | Sugitani K et al. | β | 2025 | β |
| The role of KLF4 in phagocyte activation during infectious diseases. | Herta T et al. | β | 2025 | β |
| The secrets of menstrual blood: emerging frontiers from diagnostic tools to stem cell therapies. | Feng Y et al. | β | 2025 | β |
| The Use of MSCs, iPSCs, and EVs in the Repair of Human MSK Tissues: Is Ultimate Success Dependent on Developing Excellent Implant Materials as Well as Creating an Optimal Environment for Implantation? What Is the Rationale for These Choices? | Hart DA | β | 2025 | β |
| The Use of Neurons Derived from Pluripotent Stem Cells to Study Nerve-Cancer Cell Interactions. | JimΓ©nez A et al. | β | 2025 | β |
| Three-Dimensional Bioprinting for Intervertebral Disc Regeneration. | Tanvir MAH et al. | β | 2025 | β |
| Three-Dimensional Cell Culture Scaffold Supports Capillary-Like Network Formation by Endothelial Cells Derived from Porcine-Induced Pluripotent Stem Cells. | Liao YJ et al. | β | 2025 | β |
| Tissue-Engineered Three-Dimensional Platforms for Disease Modeling and Therapeutic Development. | Wheeler EE et al. | β | 2025 | β |
| Tissue Engineering and Regenerative Medicine: Perspectives and Challenges. | Hoang VT et al. | β | 2025 | β |
| Topological data analysis of pattern formation of human induced pluripotent stem cell colonies. | Hartsock I et al. | β | 2025 | β |
| To recruit or to graft? Comparing the recruitment of resident non-neuronal cells by lineage reprogramming with engraftment of stem cell-derived neurons for neuronal replacement therapies. | Peterson DA | β | 2025 | β |
| Totipotent-like reprogramming: Molecular machineries and chemical manipulations. | Cai W et al. | β | 2025 | β |
| Towards a Comprehensive Framework for Made-to-Measure Alginate Scaffolds for Tissue Engineering Using Numerical Simulation. | BΓ€umchen A et al. | β | 2025 | β |
| Towards the establishment of treatments for neurodegenerative diseases using human iPSCs. | Inoue H | β | 2025 | β |
| Toxicity assessment using neural organoids: innovative approaches and challenges. | Park SH et al. | β | 2025 | β |
| Tracing mitochondrial marks of neuronal aging in iPSCs-derived neurons and directly converted neurons. | Varghese N et al. | β | 2025 | β |
| Transcriptional Factors Related to Cellular Kinetics, Apoptosis, and Tumorigenicity in Equine Adipose-Derived Mesenchymal Stem Cells (ASCs) Are Influenced by the Age of the Donors. | Vachkova E et al. | β | 2025 | β |
| Transcriptional regulation as a dose-dependent process: insights from transcription factor tuning. | Noviello G | β | 2025 | β |
| Transcription Factor-Based Differentiation of Pluripotent Stem Cells: Overcoming the Traps of Random Neuronal Fate. | McDaid G et al. | β | 2025 | β |
| Transplantation of vascularized cardiac microtissue from human induced pluripotent stem cells improves impaired electrical conduction in a porcine myocardial injury model. | Kuroda Y et al. | β | 2025 | β |
| Trials and tribulations of cell therapy for heart failure: an update on ongoing trials. | Zhang JJ et al. | β | 2025 | β |
| Two- and Three-Dimensional In Vitro Models of Parkinson's and Alzheimer's Diseases: State-of-the-Art and Applications. | Solana-Manrique C et al. | β | 2025 | β |
| Understanding Human Oncogene Function and Cooperativity in Myeloid Malignancy Using iPSCs. | Sarchi M et al. | β | 2025 | β |
| Understanding the Mechanisms of Chemotherapy-Related Cardiotoxicity Employing hiPSC-Derived Cardiomyocyte Models for Drug Screening and the Identification of Genetic and Epigenetic Variants. | Solomon AD et al. | β | 2025 | β |
| Unleashing the Power of Induced Pluripotent stem Cells in in vitro Modelling of Lesch-Nyhan Disease. | Javed S et al. | β | 2025 | β |
| Unlocking the Potential of Induced Pluripotent Stem Cells in Revolutionizing Cancer Therapy. | Mondal A et al. | β | 2025 | β |
| Unlocking the potential of regionally activated injury/ischemia-induced stem cells for neural regeneration. | Nakagomi T | β | 2025 | β |
| Unraveling the Complexity and Advancements of Transdifferentiation Technologies in the Biomedical Field and Their Potential Clinical Relevance. | Mishra P et al. | β | 2025 | β |
| Untangling the Molecular Mechanisms Contributing to Autism Spectrum Disorder Using Stem Cells. | Mattingly Z et al. | β | 2025 | β |
| Unveiling distinctions between mesenchymal stromal cells and stem cells by single-cell transcriptomic analysis. | Yan K et al. | β | 2025 | β |
| Updated Applications of Stem Cells in Hypoplastic Left Heart Syndrome. | Xiao R et al. | β | 2025 | β |
| Up-regulated microRNAs in blastocoel fluid of human implanted embryos could control circuits of pluripotency and be related to embryo competence. | Battaglia R et al. | β | 2025 | β |
| Uterine Biosynthesis through Tissue Engineering: An Overview of Current Methods and Status. | Sanjeev K et al. | β | 2025 | β |
| Valeric Acid: A Gut-Derived Metabolite as a Potential Epigenetic Modulator of Neuroinflammation in the Gut-Brain Axis. | Paciolla C et al. | β | 2025 | β |
| Vascular endothelial cells derived from transgene-free pig induced pluripotent stem cells for vascular tissue engineering. | Batty L et al. | β | 2025 | β |
| Vascular models of Alzheimer's disease: An overview of recent in vitro models of the blood-brain barrier. | Takeuchi LE et al. | β | 2025 | β |
| VHL Gene Restoration Supports RCC Reprogramming to iPSCs but Does Not Ensure Line Stability. | Lichner Z et al. | β | 2025 | β |
| Visualizing Trends and Bibliometric Study in Tissue Engineering for Rotator Cuff Injuries. | Yang Z et al. | β | 2025 | β |
| Volumetric trans-scale imaging of massive quantity of heterogeneous cell populations in centimeter-wide tissue and embryo. | Ichimura T et al. | β | 2025 | β |
| Watershed year of cell and gene therapy (CGT): A review of 2024 CGT approvals. | Jian A et al. | β | 2025 | β |
| Why are imprints unstable in pluripotent stem cells? | Arez M et al. | β | 2025 | β |
| Xenograft of bio-3D printed scaffold-free cartilage constructs derived from human iPSCs to regenerate articular cartilage in immunodeficient pigs. | Nonaka T et al. | β | 2025 | β |
| Yolk Sac Elements in Tumors Derived from Pluripotent Stem Cells: Borrowing Knowledge from Human Germ Cell Tumors. | van Soest M et al. | β | 2025 | β |
| Aberrant CHCHD2-associatedΒ mitochondriopathy in Kii ALS/PDC astrocytes. | Leventoux N et al. | β | 2024 | β |
| Abnormal synaptic architecture in iPSC-derived neurons from a multi-generational family with genetic Creutzfeldt-Jakob disease. | Gojanovich AD et al. | β | 2024 | β |
| A Brief History of Cell Culture: From Harrison to Organs-on-a-Chip. | Moro LG et al. | β | 2024 | β |
| A chemical approach facilitates CRISPRa-only human iPSC generation and minimizes the number of targeted loci required. | Abujarour R et al. | β | 2024 | β |
| A comprehensive protocol for efficient differentiation of human NPCs into electrically competent neurons. | Romito E et al. | β | 2024 | β |
| A cytoplasmic form of EHMT1N methylates viral proteins to enable inclusion body maturation and efficient viral replication. | Biligiri KK et al. | β | 2024 | β |
| Addressing Cardiovascular Toxicity Risk of Electronic Nicotine Delivery Systems in the Twenty-First Century: "What Are the Tools Needed for the Job?" and "Do We Have Them?" | Chandy M et al. | β | 2024 | β |
| Advanced biomaterials for regenerative medicine and their possible therapeutic significance in treating COVID-19: a critical overview. | Sarangi AK et al. | β | 2024 | β |
| Advancements and Innovative Strategies in Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cell Therapy: A Comprehensive Review. | Shi X et al. | β | 2024 | β |
| Advancements in Antioxidant-Based Therapeutics for Spinal Cord Injury: A Critical Review of Strategies and Combination Approaches. | Shen YJ et al. | β | 2024 | β |
| Advancements in neuroregenerative and neuroprotective therapies for traumatic spinal cord injury. | Fischer G et al. | β | 2024 | β |
| Advancements in Research on Genetic Kidney Diseases Using Human-Induced Pluripotent Stem Cell-Derived Kidney Organoids. | Na DH et al. | β | 2024 | β |
| Advances, challenges and future applications of liver organoids in experimental regenerative medicine. | Gong D et al. | β | 2024 | β |
| Advances in induced pluripotent stem cell-derived cardiac myocytes: technological breakthroughs, key discoveries and new applications. | Clancy CE et al. | β | 2024 | β |
| Advances in physiological and clinical relevance of hiPSC-derived brain models for precision medicine pipelines. | Imani Farahani N et al. | β | 2024 | β |
| Advances in retinal pigment epithelial cell transplantation for retinal degenerative diseases. | Liu H et al. | β | 2024 | β |
| Advances in the Differentiation of hiPSCs into Cerebellar Neuronal Cells. | Wang Y et al. | β | 2024 | β |
| Advancing stroke therapy: innovative approaches with stem cell-derived extracellular vesicles. | Song J et al. | β | 2024 | β |
| A GGC-repeat expansion in ZFHX3 encoding polyglycine causes spinocerebellar ataxia type 4 and impairs autophagy. | Figueroa KP et al. | β | 2024 | β |
| AI in cellular engineering and reprogramming. | Capponi S et al. | β | 2024 | β |
| Angiogenic properties and intercellular communication of differentiated porcine endothelial cells in vascular therapy. | Seo BG et al. | β | 2024 | β |
| An induced pluripotent stem cell-based approach for hair follicle development and regeneration. | Sivamani P et al. | β | 2024 | β |
| An integration-free induced pluripotent stem cell line from a 42-year-old female donor with the APOE-Ξ΅2/Ξ΅2 allele. | Wang L et al. | β | 2024 | β |
| A novel ionic model for matured and paced atrial-like human iPSC-CMs integrating I<sub>Kur</sub> and I<sub>KCa</sub> currents. | Botti S et al. | β | 2024 | β |
| A Novel Recombinant Vitronectin Variant Supports the Expansion and Differentiation of Pluripotent Stem Cells in Defined Animal-Free Workflows. | Lu X et al. | β | 2024 | β |
| An Unbiased Approach to Identifying Cellular Reprogramming-Inducible Enhancers. | Klagkou E et al. | β | 2024 | β |
| An updated review on animal models to study attention-deficit hyperactivity disorder. | Kim D et al. | β | 2024 | β |
| Applications of Stem Cell-Derived Extracellular Vesicles in Nerve Regeneration. | Yavuz B et al. | β | 2024 | β |
| A Review of the Evidence for Tryptophan and the Kynurenine Pathway as a Regulator of Stem Cell Niches in Health and Disease. | Summers BS et al. | β | 2024 | β |
| Artificial Gametes and Human Reproduction in the 21st Century: An Ethical Analysis. | Villalba A | β | 2024 | β |
| A Simple Nonviral Method to Generate Human Induced Pluripotent Stem Cells Using SMAR DNA Vectors. | Hartley A et al. | β | 2024 | β |
| A single-cell atlas of the miracidium larva of <i>Schistosoma mansoni</i> reveals cell types, developmental pathways, and tissue architecture. | Attenborough T et al. | β | 2024 | β |
| A streamlined method to generate endothelial cells from human pluripotent stem cells via transient doxycycline-inducible ETV2 activation. | Luo AC et al. | β | 2024 | β |
| A suboptimal OCT4-SOX2 binding site facilitates the naΓ―ve-state specific function of a Klf4 enhancer. | Waite JB et al. | β | 2024 | β |
| Atelocollagen supports three-dimensional culture of human induced pluripotent stem cells. | Nakashima Y et al. | β | 2024 | β |
| Autism patient-derived SHANK2B<sup>Y29X</sup> mutation affects the development of ALDH1A1 negative dopamine neuron. | Lai W et al. | β | 2024 | β |
| Automated CRISPR/Cas9-based genome editing of human pluripotent stem cells using the StemCellFactory. | NieΓing B et al. | β | 2024 | β |
| BCL6B-dependent suppression of ETV2 hampers endothelial cell differentiation. | Li Z et al. | β | 2024 | β |
| Beyond skin deep: Revealing the essence of iPS cell-generated skin organoids in regeneration. | Zhang YX et al. | β | 2024 | β |
| Bioprocessing considerations for generation of iPSCs intended for clinical application: perspectives from the ISCT Emerging Regenerative Medicine Technology working group. | Song HW et al. | β | 2024 | β |
| Bone marrow stromal cell antigen 2 is broadly expressed in the different pluripotent states of human pluripotent stem cells and regulates the expression of pluripotency genes and three germ layer markers. | Choi HS et al. | β | 2024 | β |
| Brain organoid as a model to study the role of mitochondria in neurodevelopmental disorders: achievements and weaknesses. | Coronel R et al. | β | 2024 | β |
| Bridging the Gap: Advances and Challenges in Heart Regeneration from In Vitro to In Vivo Applications. | Watanabe T et al. | β | 2024 | β |
| Bridging the gap: a translational perspective in spinal cord injury. | Hassan OI et al. | β | 2024 | β |
| Building a human lung from pluripotent stem cells to model respiratory viral infections. | Turner DL et al. | β | 2024 | β |
| Calcium-Enhanced Medium-Based Delivery of Splice Modulating Antisense Oligonucleotides in 2D and 3D hiPSC-Derived Neuronal Models. | Buijsen RAM et al. | β | 2024 | β |
| Canalizing kernel for cell fate determination. | Kim N et al. | β | 2024 | β |
| Capturing totipotency in human cells through spliceosomal repression. | Li S et al. | β | 2024 | β |
| Cell-based assay to detect small molecules restoring levels of let-7 miRNAs. | Szewczyk S et al. | β | 2024 | β |
| Cell-Based Therapy for Fibrosing Interstitial Lung Diseases, Current Status, and Potential Applications of iPSC-Derived Cells. | Nakamura Y et al. | β | 2024 | β |
| Cell fate decision by a morphogen-transcription factor-chromatin modifier axis. | Ming J et al. | β | 2024 | β |
| Cell therapy for neurological disorders. | Svendsen SP et al. | β | 2024 | β |
| Cell Therapy for Retinal Degenerative Diseases: Progress and Prospects. | Wu KY et al. | β | 2024 | β |
| Cell therapy in SjΓΆgren's syndrome: opportunities and challenges. | Lu Y et al. | β | 2024 | β |
| Cell-Type-Dependent Recruitment Dynamics of FUS Protein at Laser-Induced DNA Damage Sites. | Niu Y et al. | β | 2024 | β |
| Cellular In Vitro Responses Induced by Human Mesenchymal Stem/Stromal Cell-Derived Extracellular Vesicles Obtained from Suspension Culture. | Souza ILM et al. | β | 2024 | β |
| Cellular stress and epigenetic regulation in adult stem cells. | Llewellyn J et al. | β | 2024 | β |
| Challenges and Considerations of Preclinical Development for iPSC-Based Myogenic Cell Therapy. | Sun C et al. | β | 2024 | β |
| Challenges and perspectives of heart repair with pluripotent stem cell-derived cardiomyocytes. | Eschenhagen T et al. | β | 2024 | β |
| Challenges in molecular diagnosis of multiple endocrine neoplasia. | Romanet P et al. | β | 2024 | β |
| Chaperone-mediated autophagy as a modulator of aging and longevity. | Endicott SJ | β | 2024 | β |
| Characterization of Organic Anion and Cation Transport in Three Human Renal Proximal Tubular Epithelial Models. | Meijer T et al. | β | 2024 | β |
| Chemical transdifferentiation of somatic cells to neural cells: a systematic review. | Visintin PV et al. | β | 2024 | β |
| CHIR99021 and Brdu Are Critical in Chicken iPSC Reprogramming via Small-Molecule Screening. | Jin K et al. | β | 2024 | β |
| Chromatin accessibility: biological functions, molecular mechanisms and therapeutic application. | Chen Y et al. | β | 2024 | β |
| Clinical and molecular outcomes from the 5-Year natural history study of SSADH Deficiency, a model metabolic neurodevelopmental disorder. | Tokatly Latzer I et al. | β | 2024 | β |
| Clinical characteristics and induced pluripotent stem cells (iPSCs) disease model of Fabry disease caused by a novel GLA mutation. | Gao L et al. | β | 2024 | β |
| Clinical exome analysis and targeted gene repair of the c.1354dupT variant in iPSC lines from patients with PROM1-related retinopathies exhibiting diverse phenotypes. | Puertas-Neyra K et al. | β | 2024 | β |
| Clinical translation of pluripotent stem cell-based therapies: successes and challenges. | Christiansen JR et al. | β | 2024 | β |
| Clinical trials in-a-dish for cardiovascular medicine. | Wu X et al. | β | 2024 | β |
| Compact lens-free imager using a thin-film transistor for long-term quantitative monitoring of stem cell culture and cardiomyocyte production. | Kakizuka T et al. | β | 2024 | β |
| Comparative dissection of transcriptional landscapes of human iPSC-NK differentiation and NK cell development. | Zhang L et al. | β | 2024 | β |
| Comparison of Knowledge About Induced Pluripotent Stem Cells in Relation to Gender Among Healthcare Professionals and in the General Population. | Gacic JM et al. | β | 2024 | β |
| Complete suspension culture of human induced pluripotent stem cells supplemented with suppressors of spontaneous differentiation. | Matsuo-Takasaki M et al. | β | 2024 | β |
| Comprehensive analysis of m6A modification in immune infiltration, metabolism and drug resistance in hepatocellular carcinoma. | Shi Y et al. | β | 2024 | β |
| Considerations for the development of iPSC-derived cell therapies: a review of key challenges by the JSRM-ISCT iPSC Committee. | Madrid M et al. | β | 2024 | β |
| Controlling spheroid attachment improves pancreatic beta cell differentiation from human iPS cells. | Horikawa A et al. | β | 2024 | β |
| Controlling the Expression Level of the Neuronal Reprogramming Factors for a Successful Reprogramming Outcome. | Mseis-Jackson N et al. | β | 2024 | β |
| Correction of Griscelli Syndrome Type 2 causing mutations in the <i>RAB27A</i> gene with CRISPR/Cas9. | Erol ΓD et al. | β | 2024 | β |
| Creation of an Isogenic Human iPSC-Based RGC Model of Dominant Optic Atrophy Harboring the Pathogenic Variant c.1861C>T (p.Gln621Ter) in the <i>OPA1</i> Gene. | GarcΓa-LΓ³pez M et al. | β | 2024 | β |
| Crispr-Based Editing of Human Pluripotent Stem Cells for Disease Modeling. | Chang Y et al. | β | 2024 | β |
| CRISPR CLIP: comprehensive reviews on interventional studies using precision recombinant technologies: clinical landmarks, implications, and prospects. | Chodnekar SY et al. | β | 2024 | β |
| CRISPRi: a way to integrate iPSC-derived neuronal models. | Franks SNJ et al. | β | 2024 | β |
| Current Status of Cardiac Regenerative Therapy Using Induced Pluripotent Stem Cells. | Sugiura T et al. | β | 2024 | β |
| Current trends and research topics regarding organoids: A bibliometric analysis of global research from 2000 to 2023. | Wan Y et al. | β | 2024 | β |
| Decoding Neurodegeneration: A Review of Molecular Mechanisms and Therapeutic Advances in Alzheimer's, Parkinson's, and ALS. | Toader C et al. | β | 2024 | β |
| Deletion in RMST lncRNA impairs hypothalamic neuronal development in a human stem cell-based model of Kallmann Syndrome. | Ali G et al. | β | 2024 | β |
| Derivation of two iPSC lines (KAIMRCi004-A, KAIMRCi004-B) from a Saudi patient with Biotin-Thiamine-responsive Basal Ganglia Disease (BTBGD) carrying homozygous pathogenic missense variant in theΒ SCL19A3Β gene. | Alowaysi M et al. | β | 2024 | β |
| Detection of biomagnetic signals from induced pluripotent stem cell-derived cardiomyocytes using deep learning with simulation data. | Yamaguchi T et al. | β | 2024 | β |
| Detection of Residual iPSCs Following Differentiation of iPSC-Derived Retinal Pigment Epithelial Cells. | Hill M et al. | β | 2024 | β |
| Developing enhanced immunotherapy using NKG2A knockout human pluripotent stem cell-derived NK cells. | Qin Y et al. | β | 2024 | β |
| Development of Subcutaneous SSEA3- or SSEA4-Positive Cell Capture Device. | Nakayama Y et al. | β | 2024 | β |
| DFMO inhibition of neuroblastoma tumorigenesis. | Gandra D et al. | β | 2024 | β |
| Differentiation of Human Mesenchymal Stem Cells into Corneal Epithelial Cells: Current Progress. | Setiawan AM et al. | β | 2024 | β |
| Differentiation of Sinoatrial-like Cardiomyocytes as a Biological Pacemaker Model. | Sleiman Y et al. | β | 2024 | β |
| Dissecting gene activation and chromatin remodeling dynamics in single human cells undergoing reprogramming. | Martinez-Sarmiento JA et al. | β | 2024 | β |
| Do not overlook the possibility of genome-edited somatic cells ending up in the human germline. | Chin AHB et al. | β | 2024 | β |
| Dopaminergic neuron metabolism: relevance for understanding Parkinson's disease. | Flores-Ponce X et al. | β | 2024 | β |
| Dopaminergic progenitors generated by small molecule approach survived, integrated, and promoted functional recovery in (6-OHDA) mouse model of Parkinson's disease. | Alexanian AR et al. | β | 2024 | β |
| E2F1-regulated USP5 contributes to the tumorigenic capacity of glioma stem cells through the maintenance of OCT4 stability. | Jiang X et al. | β | 2024 | β |
| Early Cell Lineage Formation in Mammals: Complexity, Species Diversity, and Susceptibility to Disruptions Impacting Embryo Viability. | Latham KE | β | 2024 | β |
| Effect and mechanism of T lymphocytes on human induced pluripotent stem cell-derived cardiomyocytes via Proteomics. | Ye J et al. | β | 2024 | β |
| Efficient and cost-effective differentiation of induced neural crest cells from induced pluripotent stem cells using laminin 211. | Takahashi K et al. | β | 2024 | β |
| Efficient Dlx2-mediated astrocyte-to-neuron conversion and inhibition of neuroinflammation by NeuroD1. | Liu MH et al. | β | 2024 | β |
| Efficient fabrication of 3D bioprinted functional sensory neurons using an inducible Neurogenin-2 human pluripotent stem cell line. | St Clair-Glover M et al. | β | 2024 | β |
| Efficient generation of human induced pluripotent stem cells from urine samples of patients with Fragile X syndrome. | Dionne O et al. | β | 2024 | β |
| Efficient Generation of Pancreatic Progenitor Cells from Induced Pluripotent Stem Cells Derived from a Non-Invasive and Accessible Tissue Source-The Plucked Hair Follicle. | Fatehi A et al. | β | 2024 | β |
| Embryonic Stem Cell Differentiation to Definitive Endoderm As a Model of Heterogeneity Onset During Germ Layer Specification. | Gordeev MN et al. | β | 2024 | β |
| Emerging paradigms in cancer cell plasticity. | Huh HD et al. | β | 2024 | β |
| Endogenous tagging using split mNeonGreen in human iPSCs for live imaging studies. | Husser MC et al. | β | 2024 | β |
| Endothelin-1 influences mechanical properties and contractility of hiPSC derived cardiomyocytes resulting in diastolic dysfunction. | Redwanz C et al. | β | 2024 | β |
| Energy Metabolism in Human Pluripotent Stem and Differentiated Cells Compared Using a Seahorse XF96 Extracellular Flux Analyzer. | Kim HK et al. | β | 2024 | β |
| Engineered Cellular Therapies for the Treatment of Thoracic Cancers. | Erickson SM et al. | β | 2024 | β |
| Engineering next generation vascularized organoids. | Werschler N et al. | β | 2024 | β |
| Enhancing genome editing in hPSCs through dual inhibition of DNA damage response and repair pathways. | Park JC et al. | β | 2024 | β |
| Enrichment of Allelic Editing Outcomes by Prime Editing in Induced Pluripotent Stem Cells. | Niwa R et al. | β | 2024 | β |
| Establishment of a novel amyotrophic lateral sclerosis patient (<i>TARDBP</i> <sup>N345K/+</sup>)-derived brain microvascular endothelial cell model reveals defective Wnt/Ξ²-catenin signaling: investigating diffusion barrier dysfunction and immune cell interaction. | Matsuo K et al. | β | 2024 | β |
| Establishment of Transgene-Free Porcine Induced Pluripotent Stem Cells. | Conrad JV et al. | β | 2024 | β |
| Ethical frontiers in liver transplantation. | Wong HPN et al. | β | 2024 | β |
| Exosomes from mesenchymal stem cells: Potential applications in wound healing. | Li S et al. | β | 2024 | β |
| Experimental Cell Models for Investigating Neurodegenerative Diseases. | Evangelisti C et al. | β | 2024 | β |
| Exploring mood disorders and treatment options using human stem cells. | Hudock A et al. | β | 2024 | β |
| Exploring Stem-Cell-Based Therapies for Retinal Regeneration. | Radu M et al. | β | 2024 | β |
| Exposure to the antiretroviral drug dolutegravir impairs structure and neurogenesis in a forebrain organoid model of human embryonic cortical development. | LaNoce E et al. | β | 2024 | β |
| Extracellular Vesicles from Human Induced Pluripotent Stem Cells Exhibit a Unique MicroRNA and CircRNA Signature. | Barilani M et al. | β | 2024 | β |
| Ferroptosis in diabetic cardiomyopathy: Advances in cardiac fibroblast-cardiomyocyte interactions. | Wang M et al. | β | 2024 | β |
| Finishing the odyssey to a stem cell cure for type 1 diabetes. | Hunault L et al. | β | 2024 | β |
| From banked human cord blood to induced pluripotent stem cells: New opportunities and promise in induced pluripotent stem cell banking (Review). | Roslan FF et al. | β | 2024 | β |
| Gellan gum-gelatin based cardiac models support formation of cellular networks and functional cardiomyocytes. | VuorenpÀÀ H et al. | β | 2024 | β |
| Gene editing and reprogramming of human fibroblast cells (hFBs) to human pluripotent stem cells (hiPSCs). | Zhang Z et al. | β | 2024 | β |
| Generation of an inducible dCas9-SAM human PSC line for endogenous gene activation. | Petazzi P et al. | β | 2024 | β |
| Generation of dual-attribute iTNK cells from hPSCs for cancer immunotherapy. | Zhang Y et al. | β | 2024 | β |
| Generation of Human-induced Pluripotent Stem Cells Derived From Dermal Fibroblast of Schizophrenic Patients. | Parvishan A et al. | β | 2024 | β |
| Generation of human-induced pluripotent stem cells from a patient with homozygous I1234V mutation of cystic fibrosis. | Emara MM et al. | β | 2024 | β |
| Generation of induced pluripotent stem cells from an HLA-B27 positive ankylosing spondylitis patient with syndesmophyte formation. | Tsai WH et al. | β | 2024 | β |
| Generation of induced pluripotent stem cells from the Asian bats. | Lee Y et al. | β | 2024 | β |
| Genome editing iPSC to purposing enhancement of induce CD8 killer T cell function for regenerative immunotherapy. | Kurihara S et al. | β | 2024 | β |
| Germ cell tumors, cell surface markers, and the early search for human pluripotent stem cells. | Andrews PW | β | 2024 | β |
| GraphMHC: Neoantigen prediction model applying the graph neural network to molecular structure. | Jeong H et al. | β | 2024 | β |
| Guidelines for Manufacturing and Application of Organoids: Liver. | Moon HR et al. | β | 2024 | β |
| Harnessing developmental dynamics of spinal cord extracellular matrix improves regenerative potential of spinal cord organoids. | Sun Z et al. | β | 2024 | β |
| Harnessing the potential of human induced pluripotent stem cells, functional assays and machine learning for neurodevelopmental disorders. | Yang Z et al. | β | 2024 | β |
| Heart and vessels from stem cells: A short history of serendipity and good luck. | Mummery C | β | 2024 | β |
| Highly Defined Induced Pluripotent Stem Cell Lines Mimic Donor Red Blood Cell Antigen Profiles for Therapeutic and Diagnostic Use. | Catelli LF et al. | β | 2024 | β |
| Highly Durable, Stretchable Multielectrode Array for Electro-mechanical Co-stimulation of Cells. | Kim AR et al. | β | 2024 | β |
| High resolution long-read telomere sequencing reveals dynamic mechanisms in aging and cancer. | Schmidt TT et al. | β | 2024 | β |
| How is Excitotoxicity Being Modelled in iPSC-Derived Neurons? | Cheng JL et al. | β | 2024 | β |
| Human developmental biology - a global perspective. | Clark AT et al. | β | 2024 | β |
| Human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) for modeling cardiac arrhythmias: strengths, challenges and potential solutions. | Joshi J et al. | β | 2024 | β |
| Human in vitro models for Fabry disease: new paths for unravelling disease mechanisms and therapies. | Borisch C et al. | β | 2024 | β |
| Human iPSC and CRISPR targeted gene knock-in strategy for studying the somatic TIE2<sup>L914F</sup> mutation in endothelial cells. | Lazovic B et al. | β | 2024 | β |
| Human-mouse chimeric brain models constructed from iPSC-derived brain cells: Applications and challenges. | Zhao Y et al. | β | 2024 | β |
| Human patient derived organoids: an emerging precision medicine model for gastrointestinal cancer research. | Yan S et al. | β | 2024 | β |
| Human stem cell models for Marfan syndrome: a <i>brief overview of the rising star in disease modelling</i>. | Aalders J et al. | β | 2024 | β |
| Hydrogel-Based Strategies for Liver Tissue Engineering. | Zhang Y et al. | β | 2024 | β |
| Hypoxia Increases the Efficiencies of Cellular Reprogramming and Oncogenic Transformation in Human Blood Cell Subpopulations In Vitro and In Vivo. | Moratilla A et al. | β | 2024 | β |
| Ideal Living Skin Equivalents, From Old Technologies and Models to Advanced Ones: The Prospects for an Integrated Approach. | Riabinin A et al. | β | 2024 | β |
| <i>In vitro</i> detection of marine invertebrate stem cells: utilizing molecular and cellular biology techniques and exploring markers. | Mohajer F et al. | β | 2024 | β |
| <i>In Vitro</i> models of leukemia development: the role of very small leukemic stem-like cells in the cellular transformation cascade. | Lica JJ et al. | β | 2024 | β |
| <i>LMNA</i>-Related Dilated Cardiomyopathy: Single-Cell Transcriptomics during Patient-Derived iPSC Differentiation Support Cell Type and Lineage-Specific Dysregulation of Gene Expression and Development for Cardiomyocytes and Epicardium-Derived Cells with Lamin A/C Haploinsufficiency. | Zaragoza MV et al. | β | 2024 | β |
| Immune safety challenges facing the preclinical assessment and clinical progression of cell therapies. | Bates SM et al. | β | 2024 | β |
| Improving human cardiac organoid design using transcriptomics. | Hyams NA et al. | β | 2024 | β |
| Improving iPSC Differentiation Using a Nanodot Platform. | Chiew MY et al. | β | 2024 | β |
| Induced Pluripotent Stem Cells and Organoids in Advancing Neuropathology Research and Therapies. | Pazzin DB et al. | β | 2024 | β |
| Induced pluripotent stem cells (iPSCs): molecular mechanisms of induction and applications. | Cerneckis J et al. | β | 2024 | β |
| Induced pluripotent stem cell therapies in heart failure treatment: aΒ meta-analysis and systematic review. | Le DCP et al. | β | 2024 | β |
| Induction of cardiac alternans in human iPS-derived cardiomyocytes through Ξ²-adrenergic receptor stimulation. | Hinata Y et al. | β | 2024 | β |
| Induction of Pluripotent Stem Cells from Muscle Cells of Large Yellow Croaker (Larimichthys Crocea) Via Electrotransfection. | Zhong Z et al. | β | 2024 | β |
| Inhibitory Roles of <i>Apolipoprotein E</i> Christchurch Astrocytes in Curbing Tau Propagation Using Human Pluripotent Stem Cell-Derived Models. | Murakami R et al. | β | 2024 | β |
| Initial WNT/Ξ²-Catenin or BMP Activation Modulates Inflammatory Response of Mesodermal Progenitors Derived from Human Induced Pluripotent Stem Cells. | Suzdaltseva Y et al. | β | 2024 | β |
| Injectable biodegradable microcarriers for iPSC expansion and cardiomyocyte differentiation. | Bettini A et al. | β | 2024 | β |
| Insights into plant regeneration: cellular pathways and DNA methylation dynamics. | Lee S et al. | β | 2024 | β |
| Insights into the development of insulin-producing cells: Precursors correlated involvement of microRNA panels. | Pierantoni M et al. | β | 2024 | β |
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| In Vitro Models for Peripheral Nerve Regeneration. | Tusnim J et al. | β | 2024 | β |
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| iPSC-derived and Patient-Derived Organoids: Applications and challenges in scalability and reproducibility as pre-clinical models. | Heinzelmann E et al. | β | 2024 | β |
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| iPSC-derived lung and lung cancer organoid model to evaluate cisplatin encapsulated autologous iPSC-derived mesenchymal stromal cell-isolated extracellular vesicles. | KΓΌstermann C et al. | β | 2024 | β |
| iPS cell therapy 2.0: Preparing for next-generation regenerative medicine. | Hui KK et al. | β | 2024 | β |
| iPSCs chondrogenic differentiation for personalized regenerative medicine: a literature review. | Ali EAM et al. | β | 2024 | β |
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| Landscape of human organoids: Ideal model in clinics and research. | Han X et al. | β | 2024 | β |
| Looking for the philosopher's stone: Emerging approaches to target the hallmarks of aging in the skin. | Lemaitre JM | β | 2024 | β |
| Macrophages enhance contractile force in iPSC-derived human engineered cardiac tissue. | Lock RI et al. | β | 2024 | β |
| Macrophage variants in laboratory research: most are well done, but some are RAW. | Herb M et al. | β | 2024 | β |
| Maintenance of stem cell self-renewal by sex chromosomal zinc-finger transcription factors. | Kita K et al. | β | 2024 | β |
| Manipulating cell fate through reprogramming: approaches and applications. | Yagi M et al. | β | 2024 | β |
| Mapping the future of oxidative RNA damage in neurodegeneration: Rethinking the status quo with new tools. | Wheeler HB et al. | β | 2024 | β |
| Mapping the landscape of PSC-CM research through bibliometric analysis. | Li J et al. | β | 2024 | β |
| Maturation of pluripotent stem cell-derived cardiomyocytes: limitations and challenges from metabolic aspects. | Jiang X et al. | β | 2024 | β |
| Mechanically constrained into naivety. | Radisic M | β | 2024 | β |
| Mechanisms of Embryonic Stem Cell Pluripotency Maintenance and Their Application in Livestock and Poultry Breeding. | Wang Z et al. | β | 2024 | β |
| Metabolic changes of human induced pluripotent stem cell-derived cardiomyocytes and teratomas after transplantation. | Soma Y et al. | β | 2024 | β |
| Method for Large-scale Production of hIPSC Spheroids. | LemariΓ© L et al. | β | 2024 | β |
| MicroBundleCompute: Automated segmentation, tracking, and analysis of subdomain deformation in cardiac microbundles. | Kobeissi H et al. | β | 2024 | β |
| MicroBundlePillarTrack: A Python package for automated segmentation, tracking, and analysis of pillar deflection in cardiac microbundles. | Kobeissi H et al. | β | 2024 | β |
| Microcell-mediated chromosome transfer between non-identical human iPSCs. | Uno N et al. | β | 2024 | β |
| Microfluidic chip systems for characterizing glucose-responsive insulin-secreting cells equipped with FailSafe kill-switch. | Izadifar M et al. | β | 2024 | β |
| Microfluidic Mechanoporation: Current Progress and Applications in Stem Cells. | Wang R et al. | β | 2024 | β |
| Microglial APOE3 Christchurch protects neurons from Tau pathology in a human iPSC-based model of Alzheimer's disease. | Sun GG et al. | β | 2024 | β |
| Midbrain organoids for Parkinson's disease (PD) - A powerful tool to understand the disease pathogenesis. | Babu HWS et al. | β | 2024 | β |
| miR-124-3p downregulates EGR1 to suppress ischemia-hypoxia reperfusion injury in human iPS cell-derived cardiomyocytes. | Yang Q et al. | β | 2024 | β |
| Modeling Alzheimer's disease using human cell derived brain organoids and 3D models. | Fernandes S et al. | β | 2024 | β |
| Modeling inherited retinal diseases using human induced pluripotent stem cell derived photoreceptor cells and retinal pigment epithelial cells. | Seah I et al. | β | 2024 | β |
| Modeling of the brain-lung axis using organoids in traumatic brain injury: an updated review. | Kim JT et al. | β | 2024 | β |
| Modelling and drug targeting of a myeloid neoplasm with atypical 3q26/MECOM rearrangement using patient-specific iPSCs. | Nakamura M et al. | β | 2024 | β |
| Modelling phenotypes, variants and pathomechanisms of syndromic diseases in different systems. | Gregor A et al. | β | 2024 | β |
| Molars to Medicine: A Focused Review on the Pre-Clinical Investigation and Treatment of Secondary Degeneration following Spinal Cord Injury Using Dental Stem Cells. | Jenkner S et al. | β | 2024 | β |
| Molecular therapy and nucleic acid adeno-associated virus-based gene therapy delivering combinations of two growth-associated genes to MPS IVA mice. | Rintz E et al. | β | 2024 | β |
| Monozygotic twins discordant for schizophrenia differ in maturation and synaptic transmission. | Stern S et al. | β | 2024 | β |
| Multiple factors to assist human-derived induced pluripotent stem cells to efficiently differentiate into midbrain dopaminergic neurons. | Chen Y et al. | β | 2024 | β |
| Multiple lines of evidence for disruption of nuclear lamina and nucleoporins in FUS amyotrophic lateral sclerosis. | Okada K et al. | β | 2024 | β |
| Multiplex Genome Editing of Human Pluripotent Stem Cells Using Cpf1. | Ma H | β | 2024 | β |
| Narrative review of proximal tubular epithelial cell<i>in-vitro</i>co-culture models. | Varda L et al. | β | 2024 | β |
| Neither Ethical nor Prudent: Why Not to Choose Normothermic Regional Perfusion. | Omelianchuk A et al. | β | 2024 | β |
| Neural crest precursors from the skin are the primary source of directly reprogrammed neurons. | Belair-Hickey JJ et al. | β | 2024 | β |
| Neutrophil generation from hematopoietic progenitor cells and induced pluripotent stem cells (iPSCs): potential applications. | Jafarzadeh A et al. | β | 2024 | β |
| New developments in pre-clinical models of ALS to guide translation. | De Cock L et al. | β | 2024 | β |
| New from old: recycling differentiated cells into regenerative cells using traditional Chinese medicine? A tribute to Professor Rongxiang Xu. | PΓ©ault B | β | 2024 | β |
| Next-generation CRISPR technology for genome, epigenome and mitochondrial editing. | Lau CH et al. | β | 2024 | β |
| NMDA Receptors in Neurodevelopmental Disorders: Pathophysiology and Disease Models. | Tumdam R et al. | β | 2024 | β |
| Novel and effective plasmid transfection protocols for functional analysis of genetic elements in human cardiac fibroblasts. | Matsuyama M et al. | β | 2024 | β |
| Novel human iPSC models of neuroinflammation in neurodegenerative disease and regenerative medicine. | Summers RA et al. | β | 2024 | β |
| Novel Technologies to Address the Lower Motor Neuron Injury and Augment Reconstruction in Spinal Cord Injury. | Bazarek SF et al. | β | 2024 | β |
| Nuclear and cytosolic fractions of SOX2 synergize as transcriptional and translational co-regulators of cell fate. | Schaefer T et al. | β | 2024 | β |
| Odontoblasts or odontocytes, expression of stem cells markers and differentiation markers among human adult odontoblasts. | Alzer H et al. | β | 2024 | β |
| Only Some Paths Lead to Longer Healthier Life and How to Find Them. | Conboy I et al. | β | 2024 | β |
| Optimization of a human induced pluripotent stem cell-derived sensory neuron model for the in vitro evaluation of taxane-induced neurotoxicity. | Cantor EL et al. | β | 2024 | β |
| Optimized simple culture protocol for inducing mature myotubes from MYOD1-overexpressed human iPS cells. | Wada E et al. | β | 2024 | β |
| Optimizing Nodal, Wnt and BMP signaling pathways for robust and efficient differentiation of human induced pluripotent stem cells to intermediate mesoderm cells. | Magro-Lopez E et al. | β | 2024 | β |
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| Organoids for Cancer Research: Advances and Challenges. | Xin M et al. | β | 2024 | β |
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| Paracrinal regulation of neutrophil functions by coronaviral infection in iPSC-derived alveolar type II epithelial cells. | Chien Y et al. | β | 2024 | β |
| Parallel genome-scale CRISPR-Cas9 screens uncouple human pluripotent stem cell identity versus fitness. | Rosen BP et al. | β | 2024 | β |
| Parenteral nutrition emulsion inhibits CYP3A4 in an iPSC derived liver organoids testing platform. | Harrison SP et al. | β | 2024 | β |
| Patient-derived induced pluripotent stem cells with a <i>MERTK</i> mutation exhibit cell junction abnormalities and aberrant cellular differentiation potential. | Zhang H et al. | β | 2024 | β |
| Phagocytosis model of calcium oxalate monohydrate crystals generated using human induced pluripotent stem cell-derived macrophages. | Okada T et al. | β | 2024 | β |
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| Possible Strategies to Reduce the Tumorigenic Risk of Reprogrammed Normal and Cancer Cells. | Lin YC et al. | β | 2024 | β |
| Progesterone receptor is constitutively expressed in induced Pluripotent Stem Cells (iPSCs). | Manganelli M et al. | β | 2024 | β |
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| Promoting Alzheimer's disease research and therapy with stem cell technology. | Cao Z et al. | β | 2024 | β |
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| Remyelinating Drugs at a Crossroad: How to Improve Clinical Efficacy and Drug Screenings. | Al Jaf AIA et al. | β | 2024 | β |
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| Single-cell Profiling of Reprogrammed Human Neural Stem Cells Unveils High Similarity to Neural Progenitors in the Developing Central Nervous System. | Spathopoulou A et al. | β | 2024 | β |
| Single-cell RNA sequencing reveals key regulators and differentiation trajectory of iPSC-derived cardiomyocytes. | Li L et al. | β | 2024 | β |
| Single-cell transcriptomics reveals the molecular basis of human iPS cell differentiation into ectodermal ocular lineages. | Howard L et al. | β | 2024 | β |
| Single Nucleotide Polymorphism-based Identification of Bacterial Artificial Chromosome-mediated Homologous Recombination. | Chung SK | β | 2024 | β |
| SMAD3 mediates the specification of human induced pluripotent stem cell-derived epicardium into progenitors for the cardiac pericyte lineage. | Miyoshi Y et al. | β | 2024 | β |
| Soluble form of Lingo2, an autism spectrum disorder-associated molecule, functions as an excitatory synapse organizer in neurons. | Yoshida F et al. | β | 2024 | β |
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| Standardization and quality assessment for human intestinal organoids. | Lee H et al. | β | 2024 | β |
| State of the Art in Sub-Phenotyping Midbrain Dopamine Neurons. | Basso V et al. | β | 2024 | β |
| Stem-Cell-Based Small-Diameter Blood Vessels with 3D Printing. | Wang Y et al. | β | 2024 | β |
| Stem Cell-Based Therapies for Glaucoma Treatment: A Review Bridging the Gap in Veterinary Patients. | de Sousa Moreira A et al. | β | 2024 | β |
| Stem cell-based therapy for fibrotic diseases: mechanisms and pathways. | Taherian M et al. | β | 2024 | β |
| Stem Cells and Acellular Preparations in Bone Regeneration/Fracture Healing: Current Therapies and Future Directions. | Brown MG et al. | β | 2024 | β |
| Stem cells and bio scaffolds for the treatment of cardiovascular diseases: new insights. | Razavi ZS et al. | β | 2024 | β |
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| Stem cell therapies for chronic obstructive pulmonary disease: mesenchymal stem cells as a promising treatment option. | Lai S et al. | β | 2024 | β |
| Stem cell therapies for neurological disorders: current progress, challenges, and future perspectives. | Rahimi Darehbagh R et al. | β | 2024 | β |
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| Strategies for modeling aging and age-related diseases. | Jothi D et al. | β | 2024 | β |
| Study on the therapeutic potential of induced neural stem cells for Alzheimer's disease in mice. | Ji Q et al. | β | 2024 | β |
| Synergistic Effect of Electrical and Biochemical Stimulation on Human iPSC-Derived Neural Differentiation in a Microfluidic Electrode Array Chip. | Kim NY et al. | β | 2024 | β |
| Systematic Evaluation of Extracellular Coating Matrix on the Differentiation of Human-Induced Pluripotent Stem Cells to Cortical Neurons. | Li S et al. | β | 2024 | β |
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| Targeting of human cancer stem cells predicts efficacy and toxicity of FDA-approved oncology drugs. | Vojnits K et al. | β | 2024 | β |
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| The progress of induced pluripotent stem cells derived from pigs: a mini review of recent advances. | Neira JA et al. | β | 2024 | β |
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| The Role of Human-Induced Pluripotent Stem Cells in Studying Cardiac Channelopathies. | Begovic M et al. | β | 2024 | β |
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| Transglutaminase 2 Regulates HSF1 Gene Expression in the Acute Phase of Fish Optic Nerve Regeneration. | Sugitani K et al. | β | 2024 | β |
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| Trans-omic profiling uncovers molecular controls of early human cerebral organoid formation. | Chen C et al. | β | 2024 | β |
| Transplantation of chemically induced pluripotent stem-cell-derived islets under abdominal anterior rectus sheath in a type 1 diabetes patient. | Wang S et al. | β | 2024 | β |
| Transplantation of derivative retinal organoids from chemically induced pluripotent stem cells restored visual function. | Zhao N et al. | β | 2024 | β |
| Two-year safety outcomes of iPS cell-derived mesenchymal stromal cells in acute steroid-resistant graft-versus-host disease. | Kelly K et al. | β | 2024 | β |
| Unlocking the potential of iPSC-derived immune cells: engineering iNK and iT cells for cutting-edge immunotherapy. | Fang M et al. | β | 2024 | β |
| Unraveling hallmark suitability for staging pre- and post-implantation stem cell models. | Onfray C et al. | β | 2024 | β |
| Unraveling MLL1-fusion leukemia: Epigenetic revelations from an iPS cell point mutation. | Kobrossy L et al. | β | 2024 | β |
| Use of iPSC-Derived Smooth Muscle Cells to Model Physiology and Pathology. | Kwartler CS et al. | β | 2024 | β |
| Using induced pluripotent stem cells for drug discovery in arrhythmias. | Teles D et al. | β | 2024 | β |
| Using Organoids to Model Sex Differences in the Human Brain. | Pavlinek A et al. | β | 2024 | β |
| Vascular Damage and Repair - Are Small-Diameter Vascular Grafts Still the "Holy Grail" of Tissue Engineering? | BaΔΓ‘kovΓ‘ L et al. | β | 2024 | β |
| Vascularized platforms for investigating cell communication via extracellular vesicles. | Kim J et al. | β | 2024 | β |
| "When does human life begin?" teaching human embryology in the context of the American abortion debate. | Gilbert SF | β | 2024 | β |
| Efficient deletion of microRNAs using CRISPR/Cas9 with dual guide RNAs. | Ijee S et al. | β | 2023 | β |