The neuropathology of alcohol-related brain damage.
paper
Cited
Public
Unavailable
- Authors
- Harper, Clive
- Year
- 2009
- Journal
- Alcohol and alcoholism (Oxford, Oxfordshire)
- PMID
- 19147798
- DOI
- 10.1093/alcalc/agn102
Excessive alcohol use can cause structural and functional abnormalities of the brain and this has significant health, social and economic implications for most countries in the world. Even heavy social drinkers who have no specific neurological or hepatic problems show signs of regional brain damage and cognitive dysfunction. Changes are more severe and other brain regions are damaged in patients who have additional vitamin B1 (thiamine) deficiency (Wernicke-Korsakoff syndrome). Quantitative studies and improvements in neuroimaging have contributed significantly to the documentation of these changes but mechanisms underlying the damage are not understood. A human brain bank targeting alcohol cases has been established in Sydney, Australia, and tissues can be used for structural and molecular studies and to test hypotheses developed from animal models and in vivo studies. The recognition of potentially reversible changes and preventative medical approaches are important public health issues.
No figures extracted from this document.
No chunks β full text not yet ingested.
No entities extracted from this document yet.
No uploaded files.
Not in any collection.
No citations found.
In this knowledge base
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Differentially expressed proteins in the prefrontal cortex of individuals with alcohol use disorder: a multi-level biological network analysis. | Hoefel LPL et al. | β | 2026 | β |
| Weizmannia coagulans BC99 alleviates alcohol-induced oxidative stress and gut barrier dysfunction via modulation of butyrate metabolism: A randomized, double-blind, placebo-controlled trial. | Wang Y et al. | β | 2026 | β |
| Acupuncture for alcohol use disorder: Research status and potential strategies to improve therapeutic efficacy. | Gao H et al. | β | 2025 | β |
| Alcohol consumption and cerebrospinal fluid biomarkers for preclinical alzheimer's disease in a population-based sample of 70-year-olds. | Kern S et al. | β | 2025 | β |
| A network pharmacology approach and experimental validation to investigate the neuroprotective mechanism of quercetin against alcoholic brain injury via the JNK/P38 MAPK signaling pathway. | Zhang Y et al. | β | 2025 | β |
| Associations of moderate alcohol intake with cerebrospinal fluid biomarkers of Alzheimer's disease: data from the ALBION study. | Drouka A et al. | β | 2025 | β |
| Chronic alcohol consumption induces phenotypic and functional alterations consistent with a hyper-inflammatory state in peripheral blood mononuclear cell-derived microglia in a rhesus macaque model. | Hemati H et al. | β | 2025 | β |
| Cognitive Performance in Patients With Alcohol-Associated Liver Disease Undergoing Liver Transplantation. | Grusiecka-StaΕczyk M et al. | β | 2025 | β |
| Comparative Analysis of Blood MMP-9 Concentration in Alcohol- and Opioid-Addicted Patients. | Kartvelishvili T et al. | β | 2025 | β |
| Integrating mental & physical health: Towards a paradigm shift. | Murthy P | β | 2025 | β |
| N-acetylcysteine (NAC) ameliorates ethanol-induced oxidative stress, neuroinflammation, and cognitive dysfunction in APP/PS1 mouse model. | Pan X et al. | β | 2025 | β |
| Neuroanatomical and Psychosocial Effects of Heavy Alcohol Use Among Young Adults in Angola: A Cross-Sectional Study. | Guerra BO et al. | β | 2025 | β |
| Variation of Myelin-associated Gene Expression and <i>Ndrg1</i> within the Prefrontal Cortex as Determinants for Initial Level of Response to Alcohol | Wolstenholme JT et al. | β | 2025 | β |
| Vitamin Bs as Potent Anticancer Agents through MMP-2/9 Regulation. | Vo HVT et al. | β | 2025 | β |
| Abstinence as Choice: Exploring Voluntary Abstinence from Alcohol Self-Administration Using the Resurgence-as-Choice Framework. | Craig AR et al. | β | 2024 | β |
| Adolescent binge ethanol impacts H3K9me3-occupancy at synaptic genes and the regulation of oligodendrocyte development. | Brocato ER et al. | β | 2024 | β |
| Alcohol consumers with liver pathology rarely display Ξ±-synuclein pathology. | Libard S et al. | β | 2024 | β |
| Alcohol-related cognitive impairments in patients with and without cirrhosis. | Angerville B et al. | β | 2024 | β |
| Alcohol Use Disorder and Dementia: A Review. | Zahr NM | β | 2024 | β |
| Association between alcohol consumption and incidence of dementia in current drinkers: linear and non-linear mendelian randomization analysis. | Zheng L et al. | β | 2024 | β |
| Changes of neurofilament light chain in patients with alcohol dependence following withdrawal and the genetic effect from ALDH2 Polymorphism. | Huang MC et al. | β | 2024 | β |
| Chronic Alcohol Exposure Alters the Levels and Assembly of the Actin Cytoskeleton and Microtubules in the Adult Mouse Hippocampus. | Gao DP et al. | β | 2024 | β |
| Cognitive deficits persisting in patients with alcohol dependence syndrome after detoxification. | Sachdeva A et al. | β | 2024 | β |
| Cognitive impairment in patients awaiting kidney and liver transplantation-A clinically relevant problem? | Golenia A et al. | β | 2024 | β |
| Differential regulation of G protein-coupled receptor-associated proteins in the caudate and the putamen of cynomolgus macaques following chronic ethanol drinking. | Neel AI et al. | β | 2024 | β |
| Excessive intragastric alcohol administration exacerbates hepatic encephalopathy and provokes neuronal cell death in male rats with chronic liver disease. | Tamnanloo F et al. | β | 2024 | β |
| Macroscopic and Microscopic Cerebral Findings in Drug and Alcohol Abusers: The Point of View of the Forensic Pathologist. | Montana A et al. | β | 2024 | β |
| Neuropathology of deaths due to acute alcohol toxicity in Australia, 2011-2022. | Darke S et al. | β | 2024 | β |
| Patterns of Alcohol Use in Hispanic Individuals with TBI over the Ten Years Post-Injury: A Model Systems Study. | Arango-Lasprilla JC et al. | β | 2024 | β |
| The Association between Individual Food Groups, Limbic System White Matter Tracts, and Episodic Memory: Initial Data from the Aiginition Longitudinal Biomarker Investigation of Neurodegeneration (ALBION) Study. | Christidi F et al. | β | 2024 | β |
| Towards a Non-pharmacological Intervention on Apathy in Korsakoff's Syndrome: A Systematic Narrative Review Across Different Clinical Conditions. | van Dorst MEG et al. | β | 2024 | β |
| Alcohol and the central nervous system. | Wolfe M et al. | β | 2023 | β |
| Animal models for studies of alcohol effects on the trajectory of age-related cognitive decline. | Foster TC | β | 2023 | β |
| Brain proteomic atlas of alcohol use disorder in adult males. | Teng PN et al. | β | 2023 | β |
| Cerebellar Transcriptomic Analysis in a Chronic plus Binge Mouse Model of Alcohol Use Disorder Demonstrates Ethanol-Induced Neuroinflammation and Altered Glial Gene Expression. | Holloway KN et al. | β | 2023 | β |
| Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation. | Niedzwiedz-Massey VM et al. | β | 2023 | β |
| Gender inequalities as contributors to dementia in Latin America and the Caribbean: what factors are missing from research? | Ribeiro FS et al. | β | 2023 | β |
| Informing the development of diagnostic criteria for differential diagnosis of alcohol-related cognitive impairment (ARCI) among heavy drinkers: A systematic scoping review. | Jones L et al. | β | 2023 | β |
| Neurocognitive Recovery in Abstinent Patients with Alcohol Use Disorder: A Scoping Review for Associated Factors. | Staudt J et al. | β | 2023 | β |
| Neurotoxicology of alcohol: a bibliometric and science mapping analysis. | Mendes PFS et al. | β | 2023 | β |
| Observations on the Clinical Features of the Wernicke-Korsakoff Syndrome. | Kopelman MD | β | 2023 | β |
| Over a Century of Study and Still Misunderstood: Recognizing the Spectrum of Acute and Chronic Wernicke-Korsakoff Syndrome. | Scalzo SJ et al. | β | 2023 | β |
| Structural brain substrates of the deficits observed on the BEARNI test in alcohol use disorder and Korsakoff's syndrome. | Ritz L et al. | β | 2023 | β |
| The Possible Role of Naringenin in the Prevention of Alcohol-Induced Neurochemical and Neurobehavioral Deficits. | Soliman NA et al. | β | 2023 | β |
| A coordinate-based meta-analysis of white matter alterations in patients with alcohol use disorder. | Spindler C et al. | β | 2022 | β |
| A Dose-Response Relationship of Alcohol Consumption with Risk of Visual Impairment in Korean Adults: The Kangbuk Samsung Health Study. | Han SY et al. | β | 2022 | β |
| Association of Motoric Cognitive Risk Syndrome with Cardiovascular and Noncardiovascular Factors: A Systematic Review and Meta-Analysis. | Iqbal K et al. | β | 2022 | β |
| Cognitive decline and alcohol consumption in the aging population-A longitudinal analysis of the Survey of Health, Ageing and Retirement in Europe. | Listabarth S et al. | β | 2022 | β |
| Disinhibition-Like Behavior Correlates with Frontal Cortex Damage in an Animal Model of Chronic Alcohol Consumption and Thiamine Deficiency. | Moya M et al. | β | 2022 | β |
| Effect of chronic intermittent ethanol vapor exposure on RNA content of brain-derived extracellular vesicles. | Baratta AM et al. | β | 2022 | β |
| Genome-wide transcriptomics of the amygdala reveals similar oligodendrocyte-related responses to acute and chronic alcohol drinking in female mice. | Narendra S et al. | β | 2022 | β |
| MRI Analysis Of the Water Content Change In the Brain During Acute Ethanol Consumption Via Quantitative Water Mapping. | Furtmann JK et al. | β | 2022 | β |
| Neuropsychological Profile of College Students Who Engage in Binge Drinking. | Kang JG et al. | β | 2022 | β |
| Risky drinking and cognitive impairment in community residents aged 50 andΒ over. | Rao R et al. | β | 2022 | β |
| Upregulation of TLR4/MyD88 pathway in alcohol-induced Wernicke's encephalopathy: Findings in preclinical models and in a postmortem human case. | Moya M et al. | β | 2022 | β |
| Alcohol induced impairment/abnormalities in brain: Role of MicroRNAs. | Sushma et al. | β | 2021 | β |
| Association between thiamine decrease and neuropsychiatric symptoms in gastrointestinal and hematological cancer patients receiving chemotherapy. | Iimura Y et al. | β | 2021 | β |
| Astroglia in the Vulnerability and Maintenance of Alcohol Use Disorders. | Miguel-Hidalgo JJ | β | 2021 | β |
| Behavioral, Emotional and Social Apathy in Alcohol-Related Cognitive Disorders. | van Dorst MEG et al. | β | 2021 | β |
| Effect of alcohol on the central nervous system to develop neurological disorder: pathophysiological and lifestyle modulation can be potential therapeutic options for alcohol-induced neurotoxication. | Pervin Z et al. | β | 2021 | β |
| Evaluation of the retinal nerve fiber layer with optic coherence tomography in patients with alcohol use disorder. | Εahin T et al. | β | 2021 | β |
| History of drinking problems diminishes the protective effects of within-guideline drinking on 18-year risk of dementia and CIND. | Brennan PL et al. | β | 2021 | β |
| Intrinsic dialogues between the two hemispheres in middle-aged male alcoholics: a resting-state functional MRI study. | Dai X et al. | β | 2021 | β |
| New Australian guidelines for the treatment of alcohol problems: an overview of recommendations. | Haber PS et al. | β | 2021 | β |
| Nutritional Status and Diet Style Affect Cognitive Function in Alcoholic Liver Disease. | Choi YR et al. | β | 2021 | β |
| Promoting Successful Cognitive Aging: A Ten-Year Update. | Krivanek TJ et al. | β | 2021 | β |
| Thiamine Deficiency and Neurological Symptoms in Patients with Hematological Cancer Receiving Chemotherapy: A Retrospective Analysis. | Iimura Y et al. | β | 2021 | β |
| Alcohol and Dementia - What is the Link? A Systematic Review. | Wiegmann C et al. | β | 2020 | β |
| A multimodal investigation of cerebellar integrity associated with high-risk cannabis use. | Sweigert J et al. | β | 2020 | β |
| Association of Alcohol-Induced Loss of Consciousness and Overall Alcohol Consumption With Risk for Dementia. | KivimΓ€ki M et al. | β | 2020 | β |
| Association of moderate alcohol intake with in vivo amyloid-beta deposition in human brain: A cross-sectional study. | Kim JW et al. | β | 2020 | β |
| A systematic review of treatments for alcohol-related cognitive impairment: lessons from the past and gaps for future interventions. | Caballeria E et al. | β | 2020 | β |
| Brain 18FDG-PET pattern in patients with alcohol-related cognitive impairment. | Clergue-Duval V et al. | β | 2020 | β |
| Curcumin treatment attenuates alcohol-induced alterations in a mouse model of foetal alcohol spectrum disorders. | Cantacorps L et al. | β | 2020 | β |
| Does thiamine protect the brain from iron overload and alcohol-related dementia? | Listabarth S et al. | β | 2020 | β |
| Ethanol-Induced Changes in Brain of Transgenic Mice Overexpressing DYRK1A. | Fructuoso M et al. | β | 2020 | β |
| Ethanol induces maladaptive impulse control and decreased seeking behaviors in mice. | Starski P et al. | β | 2020 | β |
| Ginsenoside Rg1 alleviates repeated alcohol exposure-induced psychomotor and cognitive deficits. | Huang L et al. | β | 2020 | β |
| <i>Ent</i>-Peniciherqueinone Suppresses Acetaldehyde-Induced Cytotoxicity and Oxidative Stress by Inducing ALDH and Suppressing MAPK Signaling. | Oh T et al. | β | 2020 | β |
| Influence of Alcohol and Red Meat Consumption on Life Expectancy: Results of 164 Countries from 1992 to 2013. | Ranabhat CL et al. | β | 2020 | β |
| Leptin predicts cortical and subcortical gray matter volume recovery in alcohol dependent patients: A longitudinal structural magnetic resonance imaging study. | Bach P et al. | β | 2020 | β |
| Network preservation reveals shared and unique biological processes associated with chronic alcohol abuse in NAc and PFC. | Vornholt E et al. | β | 2020 | β |
| Prospective Study Examining the Effects of Extreme Drinking on Brain Structure in Emerging Adults. | Hua JPY et al. | β | 2020 | β |
| Sex and Age Effects on Neurobehavioral Toxicity Induced by Binge Alcohol. | Cortez I et al. | β | 2020 | β |
| The effect of alcohol withdrawal syndrome severity on sleep, brain and cognition. | Laniepce A et al. | β | 2020 | β |
| The Effect of Chronic Ethanol Exposure and Thiamine Deficiency on Myelin-related Genes in the Cortex and the Cerebellum. | Chatterton BJ et al. | β | 2020 | β |
| Aging with alcohol-related brain damage: Critical brain circuits associated with cognitive dysfunction. | Nunes PT et al. | β | 2019 | β |
| Alcohol-responsive genes identified in human iPSC-derived neural cultures. | Jensen KP et al. | β | 2019 | β |
| Alcohol use and dementia: a systematic scoping review. | Rehm J et al. | β | 2019 | β |
| A Pivotal Role for Thiamine Deficiency in the Expression of Neuroinflammation Markers in Models of Alcohol-Related Brain Damage. | Toledo Nunes P et al. | β | 2019 | β |
| At the intersection of alcohol use disorder and chronic pain. | Maleki N et al. | β | 2019 | β |
| Chronic Neurologic Effects of Alcohol. | Hammoud N et al. | β | 2019 | β |
| Chronic voluntary alcohol consumption causes persistent cognitive deficits and cortical cell loss in a rodent model. | Charlton AJ et al. | β | 2019 | β |
| Cross-Species Co-analysis of Prefrontal Cortex Chronic Ethanol Transcriptome Responses in Mice and Monkeys. | Bogenpohl JW et al. | β | 2019 | β |
| Dissociating thalamic alterations in alcohol use disorder defines specificity of Korsakoff's syndrome. | Segobin S et al. | β | 2019 | β |
| Exercise-driven restoration of the alcohol-damaged brain. | West RK et al. | β | 2019 | β |
| Function and Mechanism of Myelin Regulation in Alcohol Abuse and Alcoholism. | Rice J et al. | β | 2019 | β |
| Initial researches on neuro-functional status and evolution in chronic ethanol consumers with recent traumatic spinal cord injury. | Stoica SI et al. | β | 2019 | β |
| Modifiable risk factors for young onset dementia. | Cations M et al. | β | 2019 | β |
| PARP inhibition in vivo blocks alcohol-induced brain neurodegeneration and neuroinflammatory cytosolic phospholipase A2 elevations. | Kouzoukas DE et al. | β | 2019 | β |
| Thiamine for preventing dementia development among patients with alcohol use disorder: A nationwide population-based cohort study. | Chou WP et al. | β | 2019 | β |
| Whole-brain morphometric studies in alcohol addicts by voxel-based morphometry. | Li J et al. | β | 2019 | β |
| Widespread Cognitive Deficits in Alcoholism Persistent Following Prolonged Abstinence: An Updated Meta-analysis of Studies That Used Standardised Neuropsychological Assessment Tools. | Crowe SF et al. | β | 2019 | β |
| Alcohol intake and brain white matter in middle aged men: Microscopic and macroscopic differences. | McEvoy LK et al. | β | 2018 | β |
| Chronic ethanol consumption: role of TLR3/TRIF-dependent signaling. | McCarthy GM et al. | β | 2018 | β |
| Chronic ethanol exposure induces SK-N-SH cell apoptosis by increasing N-methyl-D-aspartic acid receptor expression and intracellular calcium. | Wang H et al. | β | 2018 | β |
| Chronic ethanol forced administration from adolescence to adulthood reduces cell density in the rat spinal cord. | Fernandes RM et al. | β | 2018 | β |
| Diagnosis makes a difference: Perceptions of older persons with dementia symptoms. | Diekfuss JA et al. | β | 2018 | β |
| Heavy Chronic Ethanol Exposure From Adolescence to Adulthood Induces Cerebellar Neuronal Loss and Motor Function Damage in Female Rats. | da Silva FBR et al. | β | 2018 | β |
| Identification and Evaluation of Neuropsychological Tools Used in the Assessment of Alcohol-Related Cognitive Impairment: A Systematic Review. | Heirene R et al. | β | 2018 | β |
| Molecular Neuropathology of Astrocytes and Oligodendrocytes in Alcohol Use Disorders. | Miguel-Hidalgo JJ | β | 2018 | β |
| Protocol for a randomised controlled trial of cognitive bias modification training during inpatient withdrawal from alcohol use disorder. | Manning V et al. | β | 2018 | β |
| The Loss of Ξ±- and Ξ²-Tubulin Proteins Are a Pathological Hallmark of Chronic Alcohol Consumption and Natural Brain Ageing. | Labisso WL et al. | β | 2018 | β |
| Acupuncture for Alcohol Use Disorder: A Meta-Analysis. | Shin NY et al. | β | 2017 | β |
| Adipose tissue autophagy and homeostasis in alcohol-induced liver injury. | Li Y et al. | β | 2017 | β |
| Alcohol-Related Dementia: A Systemic Review of Epidemiological Studies. | Cheng C et al. | β | 2017 | β |
| Alcohol-related diseases. | Weis S et al. | β | 2017 | β |
| Alcohol use is associated with thinner cerebral cortex and larger ventricles in schizophrenia, bipolar disorder and healthy controls. | Lange EH et al. | β | 2017 | β |
| Alteration of Ξ±-N-acetylgalactosaminidase (nagalase) concentration in alcohol-dependent individuals without liver disease, during the detoxification therapy. | Zoga M et al. | β | 2017 | β |
| Cognition and adaptive functioning in older people attending drug and alcohol services. | Monds LA et al. | β | 2017 | β |
| Expression of NMDA receptor and microRNA-219 in rats submitted to cerebral ischemia associated with alcoholism. | Silva CI et al. | β | 2017 | β |
| Korsakoff's syndrome: a critical review. | Arts NJ et al. | β | 2017 | β |
| Neuroimaging of chronic alcohol misuse. | Logan C et al. | β | 2017 | β |
| Quantitative analysis of nanoscale intranuclear structural alterations in hippocampal cells in chronic alcoholism via transmission electron microscopy imaging. | Sahay P et al. | β | 2017 | β |
| The importance of mammillary body efferents for recency memory: towards a better understanding of diencephalic amnesia. | Nelson AJD et al. | β | 2017 | β |
| Thiamine deficiency, oxidative metabolic pathways and ethanol-induced neurotoxicity: how poor nutrition contributes to the alcoholic syndrome, as Marchiafava-Bignami disease. | Fernandes LMP et al. | β | 2017 | β |
| [Thiamine (vitamin B1) treatment in patients with alcohol dependence]. | Dervaux A et al. | β | 2017 | β |
| White matter integrity between left basal ganglia and left prefrontal cortex is compromised in gambling disorder. | van Timmeren T et al. | β | 2017 | β |
| Acetaldehyde Induces Cytotoxicity of SH-SY5Y Cells via Inhibition of Akt Activation and Induction of Oxidative Stress. | Yan T et al. | β | 2016 | β |
| Alcohol Interactions with Psychostimulants: An Overview of Animal and Human Studies. | Althobaiti YS et al. | β | 2016 | β |
| Alcohol-related cognitive impairment: current trends and future perspectives. | Hayes V et al. | β | 2016 | β |
| Alcohol-Related Dementia and Neurocognitive Impairment: A Review Study. | Sachdeva A et al. | β | 2016 | β |
| Association between alcohol drinking behaviour and cognitive function: results from a nationwide longitudinal study of South Korea. | Kim S et al. | β | 2016 | β |
| Astaxanthin Inhibits Acetaldehyde-Induced Cytotoxicity in SH-SY5Y Cells by Modulating Akt/CREB and p38MAPK/ERK Signaling Pathways. | Yan T et al. | β | 2016 | β |
| Astrocyte Dysfunction Induced by Alcohol in Females but Not Males. | Wilhelm CJ et al. | β | 2016 | β |
| Changes in the female arcuate nucleus morphology and neurochemistry after chronic ethanol consumption and long-term withdrawal. | RebouΓ§as ECC et al. | β | 2016 | β |
| Chronic Drinking During Adolescence Predisposes the Adult Rat for Continued Heavy Drinking: Neurotrophin and Behavioral Adaptation after Long-Term, Continuous Ethanol Exposure. | Fernandez GM et al. | β | 2016 | β |
| Clinical and Biological Risk Factors for Neuropsychological Impairment in Alcohol Use Disorder. | Ritz L et al. | β | 2016 | β |
| Clinical neurocardiology defining the value of neuroscience-based cardiovascular therapeutics. | Shivkumar K et al. | β | 2016 | β |
| Cognitive Decline and Recovery in Alcohol Abuse. | Perry CJ | β | 2016 | β |
| Differences in cognitive function between patients with viral and alcoholic compensated liver cirrhosis. | Lee Y et al. | β | 2016 | β |
| Direct voxel-based comparisons between grey matter shrinkage and glucose hypometabolism in chronic alcoholism. | Ritz L et al. | β | 2016 | β |
| Effects of chronic alcohol consumption, withdrawal and nerve growth factor on neuropeptide Y expression and cholinergic innervation of the rat dentate hilus. | Pereira PA et al. | β | 2016 | β |
| Ethanol-Induced Neurodegeneration and Glial Activation in the Developing Brain. | Saito M et al. | β | 2016 | β |
| Landolphia owariensis Attenuates Alcohol-induced Cerebellar Neurodegeneration: Significance of Neurofilament Protein Alteration in the Purkinje Cells. | Oyinbo CA et al. | β | 2016 | β |
| Prevalence and Correlates of Neuropsychiatric Symptoms in Nursing Home Patients With Young-Onset Dementia: The BEYOnD Study. | Mulders AJ et al. | β | 2016 | β |
| A Comprehensive View of the Neurotoxicity Mechanisms of Cocaine and Ethanol. | Pereira RB et al. | β | 2015 | β |
| Brain DNA damage and behavioral changes after repeated intermittent acute ethanol withdrawal by young rats. | Costa PA et al. | β | 2015 | β |
| Brain function during cognitive flexibility and white matter integrity in alcohol-dependent patients, problematic drinkers and healthy controls. | Jansen JM et al. | β | 2015 | β |
| Change in psychiatric symptomatology after benfotiamine treatment in males is related to lifetime alcoholism severity. | Manzardo AM et al. | β | 2015 | β |
| Chronic ethanol consumption profoundly alters regional brain ceramide and sphingomyelin content in rodents. | Roux A et al. | β | 2015 | β |
| Chronic intermittent ethanol induced axon and myelin degeneration is attenuated by calpain inhibition. | Samantaray S et al. | β | 2015 | β |
| Daily marijuana use is not associated with brain morphometric measures in adolescents or adults. | Weiland BJ et al. | β | 2015 | β |
| Effects of low-level alcohol use on cognitive interference: an fMRI study in young adults. | Hatchard T et al. | β | 2015 | β |
| Functional near infrared spectroscopy as a potential biological assessment of addiction recovery: preliminary findings. | Dempsey JP et al. | β | 2015 | β |
| Gender, male-typicality, and social norms predicting adolescent alcohol intoxication and marijuana use. | Mahalik JR et al. | β | 2015 | β |
| Gut region-dependent alterations of nitrergic myenteric neurons after chronic alcohol consumption. | BagyΓ‘nszki M et al. | β | 2015 | β |
| Influence of chronic alcohol consumption on histaminergic neurons of the rat brain. | Zimatkin SM et al. | β | 2015 | β |
| Integrity of white matter microstructure in alcoholics with and without Korsakoff's syndrome. | Segobin S et al. | β | 2015 | β |
| Neurologic Manifestations of Chronic Liver Disease and Liver Cirrhosis. | Sureka B et al. | β | 2015 | β |
| Neurotoxicity of solvents. | Sainio MA | β | 2015 | β |
| Possible End to an Endless Quest? Cognitive Bias Modification for Excessive Multiplayer Online Gamers. | Rabinovitz S et al. | β | 2015 | β |
| Transplantation of bone marrow mesenchymal stem cells promotes learning and memory functional recovery and reduces hippocampal damage in rats with alcohol-associated dementia. | Yang HY et al. | β | 2015 | β |
| What does a comparison of the alcoholic Korsakoff syndrome and thalamic infarction tell us about thalamic amnesia? | Kopelman MD | β | 2015 | β |
| Alcoholism: a systemic proinflammatory condition. | GonzΓ‘lez-Reimers E et al. | β | 2014 | β |
| Alcohol-related brain damage in humans. | Erdozain AM et al. | β | 2014 | β |
| Analysis of thiamine transporter genes in sporadic beriberi. | BravatΓ V et al. | β | 2014 | β |
| Autophagy in alcohol-induced multiorgan injury: mechanisms and potential therapeutic targets. | Li Y et al. | β | 2014 | β |
| Brain proton magnetic resonance spectroscopy of alcohol use disorders. | Meyerhoff DJ | β | 2014 | β |
| Chronic ethanol exposure during adolescence in rats induces motor impairments and cerebral cortex damage associated with oxidative stress. | Teixeira FB et al. | β | 2014 | β |
| Decreased white matter integrity in fronto-occipital fasciculus bundles: relation to visual information processing in alcohol-dependent subjects. | Bagga D et al. | β | 2014 | β |
| Differential sensitivity of prefrontal cortex and hippocampus to alcohol-induced toxicity. | Fowler AK et al. | β | 2014 | β |
| Effects of ethanol on immune response in the brain: region-specific changes in adolescent versus adult mice. | Kane CJ et al. | β | 2014 | β |
| Exon microarray analysis of human dorsolateral prefrontal cortex in alcoholism. | Manzardo AM et al. | β | 2014 | β |
| Greater monoamine oxidase a binding in alcohol dependence. | Matthews BA et al. | β | 2014 | β |
| History of alcohol use disorders and risk of severe cognitive impairment: a 19-year prospective cohort study. | KuΕΊma E et al. | β | 2014 | β |
| Impact of alcohol use on inhibitory control (and vice versa) during adolescence and young adulthood: a review. | LΓ³pez-Caneda E et al. | β | 2014 | β |
| Impaired one carbon metabolism and DNA methylation in alcohol toxicity. | Kruman II et al. | β | 2014 | β |
| MicroRNAs and ethanol toxicity. | Miranda RC | β | 2014 | β |
| Neurologic complications of alcoholism. | Noble JM et al. | β | 2014 | β |
| P2X4 receptor regulates alcohol-induced responses in microglia. | Gofman L et al. | β | 2014 | β |
| Proteomic approaches and identification of novel therapeutic targets for alcoholism. | Gorini G et al. | β | 2014 | β |
| Revisiting the continuum hypothesis: toward an in-depth exploration of executive functions in korsakoff syndrome. | Brion M et al. | β | 2014 | β |
| Severe diffuse axon injury in chronic alcoholic rat medulla oblongata following a concussion blow. | Luo J et al. | β | 2014 | β |
| Understanding alcohol use disorders with neuroelectrophysiology. | Rangaswamy M et al. | β | 2014 | β |
| Wernicke encephalopathy and ethanol-related syndromes. | Kim TE et al. | β | 2014 | β |
| Alcohol-related dementia: an update of the evidence. | Ridley NJ et al. | β | 2013 | β |
| Brain-derived neurotrophic factor genotype is associated with brain gray and white matter tissue volumes recovery in abstinent alcohol-dependent individuals. | Mon A et al. | β | 2013 | β |
| High mobility group box 1/Toll-like receptor danger signaling increases brain neuroimmune activation in alcohol dependence. | Crews FT et al. | β | 2013 | β |
| Increased nitroxidative stress promotes mitochondrial dysfunction in alcoholic and nonalcoholic fatty liver disease. | Song BJ et al. | β | 2013 | β |
| Loss of control of alcohol use and severity of alcohol dependence in non-treatment-seeking heavy drinkers are related to lower glutamate in frontal white matter. | Ende G et al. | β | 2013 | β |
| Pathways to alcohol-induced brain impairment in young people: a review. | Hermens DF et al. | β | 2013 | β |
| Quantitative proteomic characterization of ethanol-responsive pathways in rat microglial cells. | Bell-Temin H et al. | β | 2013 | β |
| Role of 5-hydroxytryptamine 1B (5-HT1B) receptors in the regulation of ethanol intake in rodents. | Sari Y | β | 2013 | β |
| The neural network sustaining crossmodal integration is impaired in alcohol-dependence: an fMRI study. | Maurage P et al. | β | 2013 | β |
| The role of Ξ±-synuclein in the pathophysiology of alcoholism. | Janeczek P et al. | β | 2013 | β |
| Alcohol consumption and premotor corpus callosum in older adults. | Kapogiannis D et al. | β | 2012 | β |
| Alcohol-induced one-carbon metabolism impairment promotes dysfunction of DNA base excision repair in adult brain. | Fowler AK et al. | β | 2012 | β |
| Alcohol induces Golgi fragmentation in differentiated PC12 cells by deregulating Rab1-dependent ER-to-Golgi transport. | TomΓ‘s M et al. | β | 2012 | β |
| Alcoholism and cellular vulnerability in different brain regions. | Skuja S et al. | β | 2012 | β |
| Chronic ethanol increases systemic TLR3 agonist-induced neuroinflammation and neurodegeneration. | Qin L et al. | β | 2012 | β |
| Effect of metabotropic glutamate receptor 3 genotype on N-acetylaspartate levels and neurocognition in non-smoking, active alcoholics. | Xia Y et al. | β | 2012 | β |
| Ethanol (EtOH)-induced TGF-Ξ²1 and reactive oxygen species production are necessary for EtOH-induced alveolar macrophage dysfunction and induction of alternative activation. | Brown SD et al. | β | 2012 | β |
| Ethanol reduces expression of apoptotic proteins after hypoxia/reoxygenation in a brain slice model. | Yuan Y et al. | β | 2012 | β |
| Face-name association learning and brain structural substrates in alcoholism. | Pitel AL et al. | β | 2012 | β |
| Function and dysfunction of prefrontal brain circuitry in alcoholic Korsakoff's syndrome. | Oscar-Berman M | β | 2012 | β |
| Induction of brain CYP2E1 by chronic ethanol treatment and related oxidative stress in hippocampus, cerebellum, and brainstem. | Zhong Y et al. | β | 2012 | β |
| Long-term daily access to alcohol alters dopamine-related synthesis and signaling proteins in the rat striatum. | Kashem MA et al. | β | 2012 | β |
| Mechanisms of ethanol-induced death of cerebellar granule cells. | Luo J | β | 2012 | β |
| NADPH oxidase and reactive oxygen species contribute to alcohol-induced microglial activation and neurodegeneration. | Qin L et al. | β | 2012 | β |
| Neurocognitive parameters should be incorporated in the Minnesota Multiphasic Personality Inventory-2 assessment of patients with alcohol use disorders. | Walvoort SJ et al. | β | 2012 | β |
| Neuroimaging of Wernicke's encephalopathy and Korsakoff's syndrome. | Jung YC et al. | β | 2012 | β |
| Non-invasive brain stimulation in the functional evaluation of alcohol effects and in the treatment of alcohol craving: a review. | Nardone R et al. | β | 2012 | β |
| Your brain on drugs: imaging of drug-related changes in the central nervous system. | Tamrazi B et al. | β | 2012 | β |
| Adolescent binge drinking alters adult brain neurotransmitter gene expression, behavior, brain regional volumes, and neurochemistry in mice. | Coleman LG et al. | β | 2011 | β |
| Cortical thickness, surface area, and volume of the brain reward system in alcohol dependence: relationships to relapse and extended abstinence. | Durazzo TC et al. | β | 2011 | β |
| Differential diagnosis between dementia and psychiatric disorders: Diagnostic criteria and supplementary exams. Recommendations of the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology. | Bottino CMC et al. | β | 2011 | β |
| Differential expression of 14-3-3 isoforms in human alcoholic brain. | MacKay RK et al. | β | 2011 | β |
| Ethanol-induced changes in the expression of proteins related to neurotransmission and metabolism in different regions of the rat brain. | Zahr NM et al. | β | 2011 | β |
| Modeling neurodegenerative disease pathophysiology in thiamine deficiency: consequences of impaired oxidative metabolism. | Jhala SS et al. | β | 2011 | β |
| Molecular and behavioral aspects of the actions of alcohol on the adult and developing brain. | Alfonso-Loeches S et al. | β | 2011 | β |
| Molecular targets of alcohol action: Translational research for pharmacotherapy development and screening. | Gorini G et al. | β | 2011 | β |
| Neurological complications of alcohol and misuse of drugs. | Welch KA | β | 2011 | β |
| Pharmacological activation/inhibition of the cannabinoid system affects alcohol withdrawal-induced neuronal hypersensitivity to excitotoxic insults. | Rubio M et al. | β | 2011 | β |
| Review: The neuropathology of drug abuse. | BΓΌttner A | β | 2011 | β |
| Role of the serotonergic system in alcohol dependence: from animal models to clinics. | Sari Y et al. | β | 2011 | β |
| Signs of preclinical Wernicke's encephalopathy and thiamine levels as predictors of neuropsychological deficits in alcoholism without Korsakoff's syndrome. | Pitel AL et al. | β | 2011 | β |
| Alcohol in essential tremor and other movement disorders. | Mostile G et al. | β | 2010 | β |
| Anthocyanins: are they beneficial in treating ethanol neurotoxicity? | Chen G et al. | β | 2010 | β |
| Brain damage in a large cohort of solvent abusers. | Al-Hajri Z et al. | β | 2010 | β |
| Converging action of alcohol consumption and cannabinoid receptor activation on adult hippocampal neurogenesis. | AlΓ©n F et al. | β | 2010 | β |
| Effects of ethanol on hippocampal function during adolescence: a look at the past and thoughts on the future. | Chin VS et al. | β | 2010 | β |
| Effects of repeated withdrawal from alcohol on recovery of cognitive impairment under abstinence and rate of relapse. | Loeber S et al. | β | 2010 | β |
| Lithium-mediated protection against ethanol neurotoxicity. | Luo J | β | 2010 | β |
| Mechanisms of behavior change in alcoholics anonymous: does Alcoholics Anonymous lead to better alcohol use outcomes by reducing depression symptoms? | Kelly JF et al. | β | 2010 | β |
| Psychometric validation of the Leeds Dependence Questionnaire (LDQ) in a young adult clinical sample. | Kelly JF et al. | β | 2010 | β |
| Ten things the alcohol industry won't tell you about alcohol. | Sellman D | β | 2010 | β |
| The microstructural integrity of the corpus callosum and associated impulsivity in alcohol dependence: a tractography-based segmentation study using diffusion spectrum imaging. | Liu IC et al. | β | 2010 | β |
| From stargazing chicks to seizing infants: thiamine deficiency redux. | Patterson MC | β | 2009 | β |
| Mammillary body and fornix injury in congenital central hypoventilation syndrome. | Kumar R et al. | β | 2009 | β |
| Regional cerebral blood flow in patients with alcohol-related dementia: a SPECT study. | Chung YA et al. | β | 2009 | β |
| Role of the endocannabinoid system in ethanol-induced inhibition of salivary secretion. | Prestifilippo JP et al. | β | 2009 | β |