Childhood maltreatment and the structure of common psychiatric disorders.
paper
Cited
Public
Unavailable
- Authors
- Keyes, Katherine M; Eaton, Nicholas R; Krueger, Robert F; McLaughlin, Katie A; Wall, Melanie M; Grant, Bridget F; Hasin, Deborah S
- Year
- 2012
- Journal
- The British journal of psychiatry : the journal of mental science
- PMID
- 22157798
- DOI
- 10.1192/bjp.bp.111.093062
- PMCID
- PMC3269653
BACKGROUND: Previous research suggests that various types of childhood maltreatment frequently co-occur and confer risk for multiple psychiatric diagnoses. This non-specific pattern of risk may mean that childhood maltreatment increases vulnerability to numerous specific psychiatric disorders through diverse, specific mechanisms or that childhood maltreatment engenders a generalised liability to dimensions of psychopathology. Although these competing explanations have different implications for intervention, they have never been evaluated empirically. AIMS: We used a latent variable approach to estimate the associations of childhood maltreatment with underlying dimensions of internalising and externalising psychopathology and with specific disorders after accounting for the latent dimensions. We also examined gender differences in these associations. METHOD: Data were drawn from a nationally representative survey of 34 653 US adults. Lifetime DSM-IV psychiatric disorders were assessed using the AUDADIS-IV. Physical, sexual and emotional abuse and neglect were assessed using validated measures. Analyses controlled for other childhood adversities and sociodemographics. RESULTS: The effects were fully mediated through the latent liability dimensions, with an impact on underlying liability levels to internalising and externalising psychopathology rather than specific psychiatric disorders. Important gender differences emerged with physical abuse associated only with externalising liability in men, and only with internalising liability in women. Neglect was not significantly associated with latent liability levels. CONCLUSIONS: The association between childhood maltreatment and common psychiatric disorders operates through latent liabilities to experience internalising and externalising psychopathology, indicating that the prevention of maltreatment may have a wide range of benefits in reducing the prevalence of many common mental disorders. Different forms of abuse have gender-specific consequences for the expression of internalising and externalising psychopathology, suggesting gender-specific aetiological pathways between maltreatment and psychopathology.
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| The role of DSM-5 borderline personality symptomatology and traits in the link between childhood trauma and suicidal risk in psychiatric patients. | Bach B et al. | — | 2017 | → |
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| Incidence and Risk for Mood and Anxiety Disorders in a Representative Sample of Ohio Army National Guard Members, 2008-2012. | Fink DS et al. | — | 2016 | → |
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| Minimization of Childhood Maltreatment Is Common and Consequential: Results from a Large, Multinational Sample Using the Childhood Trauma Questionnaire. | MacDonald K et al. | — | 2016 | → |
| Onset of Alcohol Use Disorders and Comorbid Psychiatric Disorders in a Military Cohort: Are there Critical Periods for Prevention of Alcohol Use Disorders? | Fink DS et al. | — | 2016 | → |
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| The unique relation of childhood emotional maltreatment with mental health problems among detained male and female adolescents. | Vahl P et al. | — | 2016 | → |
| The variance shared across forms of childhood trauma is strongly associated with liability for psychiatric and substance use disorders. | Kristjansson S et al. | — | 2016 | → |
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| A Meta-Analysis of Cross Sectional Studies Investigating Language in Maltreated Children. | Lum JA et al. | — | 2015 | → |
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| The impact of adverse child and adult experiences on recovery from serious mental illness. | Stumbo SP et al. | — | 2015 | → |
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