Frailty models for survival data.
paper
Cited
Public
Unavailable
- Authors
- Hougaard, P
- Year
- 1995
- Journal
- Lifetime data analysis
- PMID
- 9385105
- DOI
- 10.1007/BF00985760
A frailty model is a random effects model for time variables, where the random effect (the frailty) has a multiplicative effect on the hazard. It can be used for univariate (independent) failure times, i.e. to describe the influence of unobserved covariates in a proportional hazards model. More interesting, however, is to consider multivariate (dependent) failure times generated as conditionally independent times given the frailty. This approach can be used both for survival times for individuals, like twins or family members, and for repeated events for the same individual. The standard assumption is to use a gamma distribution for the frailty, but this is a restriction that implies that the dependence is most important for late events. More generally, the distribution can be stable, inverse Gaussian, or follow a power variance function exponential family. Theoretically, large differences are seen between the choices. In practice, using the largest model makes it possible to allow for more general dependence structures, without making the formulas too complicated.
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| Title | Year | PMID |
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| High Polygenic Risk Scores Are Associated With Early Age of Onset of Alcohol Use Disorder in Adolescents and Young Adults at Risk. | 2022 | 36324664 |
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| Adversarial Time-to-Event Modeling. | Chapfuwa P et al. | β | 2018 | β |
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| Measurable residual disease, conditioning regimen intensity, and age predict outcome of allogeneic hematopoietic cell transplantation for acute myeloid leukemia in first remission: A registry analysis of 2292 patients by the Acute Leukemia Working Party European Society of Blood and Marrow Transplantation. | Gilleece MH et al. | β | 2018 | β |
| Minimal residual disease status predicts outcome of acute myeloid leukaemia patients undergoing T-cell replete haploidentical transplantation. An analysis from the Acute Leukaemia Working Party (ALWP) of the European Society for Blood and Marrow Transplantation (EBMT). | Canaani J et al. | β | 2018 | β |
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| Implant Treatment in the Predoctoral Clinic: A Retrospective Database Study of 1091 Patients. | Prasad S et al. | β | 2017 | β |
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| Estimating effectiveness in HIV prevention trials with a Bayesian hierarchical compound Poisson frailty model. | Coley RY et al. | β | 2016 | β |
| flexsurv: A Platform for Parametric Survival Modeling in R. | Jackson CH | β | 2016 | β |
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| Is there a stronger graft-versus-leukemia effect using HLA-haploidentical donors compared with HLA-identical siblings? | RingdΓ©n O et al. | β | 2016 | β |
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| Terminating observation within matched pairs of subjects in a matched cohort analysis: a Monte Carlo simulation study. | Sutradhar R et al. | β | 2016 | β |
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| Caries-preventive Effect of Supervised Toothbrushing and Sealants. | Hilgert LA et al. | β | 2015 | β |
| Composite end point of graft-versus-host disease-free, relapse-free survival after allogeneic hematopoietic cell transplantation. | Holtan SG et al. | β | 2015 | β |
| Exfoliation rates of primary molars submitted to three treatment protocols after 3.5 years. | Mijan MC et al. | β | 2015 | β |
| Longitudinal studies 3: Data modeling using standard regression models and extensions. | Ravani P et al. | β | 2015 | β |
| Modeling time-to-cure from severe acute malnutrition: application of various parametric frailty models. | Banbeta A et al. | β | 2015 | β |
| Multitarget therapy for induction treatment of lupus nephritis: a randomized trial. | Liu Z et al. | β | 2015 | β |
| Population-based comparative analysis of risk of death in children and adolescents with epilepsy and migraine. | Selassie AW et al. | β | 2015 | β |
| Survival Analysis of Faculty Retention and Promotion in the Social Sciences by Gender. | Box-Steffensmeier JM et al. | β | 2015 | β |
| Amalgam and ART restorations in children: a controlled clinical trial. | de Amorim RG et al. | β | 2014 | β |
| Association between travel distance and metastatic disease at diagnosis among patients with colon cancer. | Massarweh NN et al. | β | 2014 | β |
| Effectiveness of cranberry capsules to prevent urinary tract infections in vulnerable older persons: a double-blind randomized placebo-controlled trial in long-term care facilities. | Caljouw MA et al. | β | 2014 | β |
| Heterogeneity's ruses: the neglected role of between-individual variability in longitudinal studies of COPD exacerbations. | Sadatsafavi M et al. | β | 2014 | β |
| Is high-viscosity glass-ionomer-cement a successor to amalgam for treating primary molars? | Hilgert LA et al. | β | 2014 | β |
| Marriage duration and divorce: the seven-year itch or a lifelong itch? | Kulu H | β | 2014 | β |
| One year survival of ART and conventional restorations in patients with disability. | Molina GF et al. | β | 2014 | β |
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| Risk-adjusted pathologic margin positivity rate as a quality indicator in rectal cancer surgery. | Massarweh NN et al. | β | 2014 | β |
| Sample size determination in shared frailty models for multivariate time-to-event data. | Chen LM et al. | β | 2014 | β |
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| A simulation procedure based on copulas to generate clustered multi-state survival data. | Rotolo F et al. | β | 2013 | β |
| Beyond the randomized clinical trial: citrate for continuous renal replacement therapy in clinical practice. | Tovey L et al. | β | 2013 | β |
| Landmark risk prediction of residual life for breast cancer survival. | Parast L et al. | β | 2013 | β |
| Mixture distributions in multi-state modelling: some considerations in a study of psoriatic arthritis. | O'Keeffe AG et al. | β | 2013 | β |
| Modeling spatial frailties in survival analysis of cucurbit downy mildew epidemics. | Ojiambo PS et al. | β | 2013 | β |
| Mortality increase in late-middle and early-old age: heterogeneity in death processes as a new explanation. | Li T et al. | β | 2013 | β |
| New vertebral fractures after percutaneous vertebroplasty for painful osteoporotic vertebral compression fractures: a clustered analysis and the relevance of intradiskal cement leakage. | Nieuwenhuijse MJ et al. | β | 2013 | β |
| The atraumatic restorative treatment (ART) strategy in Mexico: two-years follow up of ART sealants and restorations. | Luengas-Quintero E et al. | β | 2013 | β |
| The impact of host species and vector control measures on the fitness of African malaria vectors. | Lyimo IN et al. | β | 2013 | β |
| The impact of low erythrocyte density in human blood on the fitness and energetic reserves of the African malaria vector Anopheles gambiae. | Emami SN et al. | β | 2013 | β |
| Use of exposure history to identify patterns of immunity to pneumonia in bighorn sheep (Ovis canadensis). | Plowright RK et al. | β | 2013 | β |
| Bone marrow or peripheral blood stem cell transplantation from unrelated donors in adult patients with acute myeloid leukaemia, an Acute Leukaemia Working Party analysis in 2262 patients. | RingdΓ©n O et al. | β | 2012 | β |
| Dislocation after total hip arthroplasty: a randomized clinical trial of a posterior approach and a modified lateral approach. | Ji HM et al. | β | 2012 | β |
| Investigating hospital heterogeneity with a multi-state frailty model: application to nosocomial pneumonia disease in intensive care units. | Liquet B et al. | β | 2012 | β |
| Nonparametric confidence intervals for the ratio of marginal hazard rates of paired survival times. | Jin H et al. | β | 2012 | β |
| Clinical features, treatment, and survival of patients with colorectal cancer with or without inflammatory bowel disease. | Ali RA et al. | β | 2011 | β |
| Frailty models: Applications to biomedical and genetic studies. | Govindarajulu US et al. | β | 2011 | β |
| Variance in Death and Its Implications for Modeling and Forecasting Mortality. | Tuljapurkar S et al. | β | 2011 | β |
| Comparative effectiveness of angiotensin-converting enzyme inhibitors versus beta-blockers as second-line therapy for hypertension. | Magid DJ et al. | β | 2010 | β |
| Effects of age and body mass index on the results of transtrochanteric rotational osteotomy for femoral head osteonecrosis. | Ha YC et al. | β | 2010 | β |
| Higher incidence of relapse in patients with acute myelocytic leukemia infused with higher doses of CD34+ cells from leukapheresis products autografted during the first remission. | Gorin NC et al. | β | 2010 | β |
| NONPARAMETRIC INFERENCE PROCEDURE FOR PERCENTILES OF THE RANDOM EFFECTS DISTRIBUTION IN META-ANALYSIS. | Wang R et al. | β | 2010 | β |
| Analyzing the occurrence of falls and its risk factors: some considerations. | Navarro A et al. | β | 2009 | β |
| Higher incidence of relapse with peripheral blood rather than marrow as a source of stem cells in adults with acute myelocytic leukemia autografted during the first remission. | Gorin NC et al. | β | 2009 | β |
| Modeling longitudinal data, II: standard regression models and extensions. | Ravani P et al. | β | 2009 | β |
| Outcome for patients treated with laparoscopic versus open resection of hepatocellular carcinoma: case-matched analysis. | Sarpel U et al. | β | 2009 | β |
| Prediction of functional loss in glaucoma from progressive optic disc damage. | Medeiros FA et al. | β | 2009 | β |
| Reduced intensity conditioning compared with myeloablative conditioning using unrelated donor transplants in patients with acute myeloid leukemia. | RingdΓ©n O et al. | β | 2009 | β |
| Semi-parametric additive risk models: application to injury duration study. | Lim HJ et al. | β | 2009 | β |
| Some alternatives in the statistical analysis of sickness absence. | Navarro A et al. | β | 2009 | β |
| Unobserved heterogeneity can confound the effect of education on mortality. | Zajacova A et al. | β | 2009 | β |
| Estimation of vaccine efficacy in a repeated measures study under heterogeneity of exposure or susceptibility to infection. | Valim C et al. | β | 2008 | β |
| Pathway analysis of microarray data via regression. | Adewale AJ et al. | β | 2008 | β |
| An examination of urban versus rural mortality in China using community and individual data. | Zimmer Z et al. | β | 2007 | β |
| Association between multidisciplinary care and survival for elderly patients with chronic kidney disease. | Hemmelgarn BR et al. | β | 2007 | β |
| Bayesian analysis of paired survival data using a bivariate exponential distribution. | Lee J et al. | β | 2007 | β |
| Comparison of methods for analyzing recurrent events data: application to the Emergency Department Visits of Pediatric Firearm Victims. | Lim HJ et al. | β | 2007 | β |
| Incorporation of inter-individual heterogeneity into the multistage carcinogenesis model: approach to the analysis of cancer incidence data. | Izumi S et al. | β | 2007 | β |
| Relationship between number of breast cancer operations performed and 5-year survival after treatment for early-stage breast cancer. | Gilligan MA et al. | β | 2007 | β |
| Selection bias in cancer risk estimation from A-bomb survivors. | Pierce DA et al. | β | 2007 | β |
| A comparative study of tests for paired lifetime data. | Wang Z et al. | β | 2006 | β |
| A population model of prostate cancer incidence. | Tsodikov A et al. | β | 2006 | β |
| Effect of highly active antiretroviral therapy on multiple AIDS-defining illnesses among male HIV seroconverters. | Cain LE et al. | β | 2006 | β |
| Generalized gamma frailty model. | Balakrishnan N et al. | β | 2006 | β |
| Nested frailty models using maximum penalized likelihood estimation. | Rondeau V et al. | β | 2006 | β |
| Predicting clustered dental implant survival using frailty methods. | Chuang SK et al. | β | 2006 | β |
| Results of genoidentical hemopoietic stem cell transplantation with reduced intensity conditioning for acute myelocytic leukemia: higher doses of stem cells infused benefit patients receiving transplants in second remission or beyond--the Acute Leukemia Working Party of the European Cooperative Group for Blood and Marrow Transplantation. | Gorin NC et al. | β | 2006 | β |
| Survival analysis for recurrent event data: an application to childhood infectious diseases. | Cain LE et al. | β | 2006 | β |
| The influence of the surgeon's and the hospital's caseload on survival and local recurrence after colorectal cancer surgery. | Renzulli P et al. | β | 2006 | β |
| Assessment of outcome over a 10-year period of patients admitted to a multidisciplinary adult intensive care unit with haematological and solid tumours. | Moran JL et al. | β | 2005 | β |
| Comparative outcome of reduced intensity and myeloablative conditioning regimen in HLA identical sibling allogeneic haematopoietic stem cell transplantation for patients older than 50 years of age with acute myeloblastic leukaemia: a retrospective survey from the Acute Leukemia Working Party (ALWP) of the European group for Blood and Marrow Transplantation (EBMT). | Aoudjhane M et al. | β | 2005 | β |
| Factors associated with time to neonatal diarrhoea in French beef calves. | Lorino T et al. | β | 2005 | β |
| Frailty and hormones. | Morley JE et al. | β | 2005 | β |
| Frailty approach for the analysis of clustered failure time observations in dental research. | Chuang SK et al. | β | 2005 | β |
| Quality effects of operative delay on mortality in hip fracture treatment. | Sund R et al. | β | 2005 | β |
| Benefit and timing of second transplantations in multiple myeloma: clinical findings and methodological limitations in a European Group for Blood and Marrow Transplantation registry study. | Morris C et al. | β | 2004 | β |
| Genetic and environmental contributions to age of onset of alcohol dependence symptoms in male twins. | Liu IC et al. | β | 2004 | β |
| Human papillomavirus type 16 and immune status in human immunodeficiency virus-seropositive women. | Strickler HD et al. | β | 2003 | β |
| Maximum penalized likelihood estimation in a gamma-frailty model. | Rondeau V et al. | β | 2003 | β |
| Rank tests for clustered survival data. | Jung SH et al. | β | 2003 | β |
| Reassessing the value of short-term mortality in sepsis: comparing conventional approaches to modeling. | Clermont G et al. | β | 2003 | β |
| An additive genetic gamma frailty model for linkage analysis of diseases with variable age of onset using nuclear families. | Li H | β | 2002 | β |
| Editorial: Something about frailty. | Morley JE et al. | β | 2002 | β |
| Proportional hazards models with frailties and random effects. | O'Quigley J et al. | β | 2002 | β |
| Proportional hazards models with random effects to examine centre effects in multicentre cancer clinical trials. | Yamaguchi T et al. | β | 2002 | β |
| Testing Gateway Theory: do cigarette prices affect illicit drug use? | Beenstock M et al. | β | 2002 | β |
| Accuracy of point predictions in survival analysis. | Henderson R et al. | β | 2001 | β |
| The influence of water storage and C-factor on the dentin-resin composite microtensile bond strength and debond pathway utilizing a filled and unfilled adhesive resin. | Armstrong SR et al. | β | 2001 | β |
| Choice of conditional models in bivariate survival. | Henderson R et al. | β | 2000 | β |
| Estimation of multivariate frailty models using penalized partial likelihood. | Ripatti S et al. | β | 2000 | β |
| Fisher information for two gamma frailty bivariate Weibull models. | Bjarnason H et al. | β | 2000 | β |
| Proportional hazards model with random effects. | Vaida F et al. | β | 2000 | β |
| Random-effects regression analysis of correlated grouped-time survival data. | Hedeker D et al. | β | 2000 | β |
| Generalized proportional hazards model based on modified partial likelihood. | Bagdonavicius VB et al. | β | 1999 | β |
| Investigating centre effects in a multi-centre clinical trial of superficial bladder cancer. | Yamaguchi T et al. | β | 1999 | β |
| State duration models in clinical and observational studies. | Lawless JF et al. | β | 1999 | β |
| Dependence estimation for marginal models of multivariate survival data. | Segal MR et al. | β | 1997 | β |
| Modelling conditional distributions in bivariate survival. | Henderson R | β | 1996 | β |