Cocaine cues and dopamine in dorsal striatum: mechanism of craving in cocaine addiction.
paper
Cited
Public
Unavailable
- Authors
- Volkow, Nora D; Wang, Gene-Jack; Telang, Frank; Fowler, Joanna S; Logan, Jean; Childress, Anna-Rose; Jayne, Millard; Ma, Yeming; Wong, Christopher
- Year
- 2006
- Journal
- The Journal of neuroscience : the official journal of the Society for Neuroscience
- PMID
- 16775146
- DOI
- 10.1523/JNEUROSCI.1544-06.2006
- PMCID
- PMC6674019
The ability of drugs of abuse to increase dopamine in nucleus accumbens underlies their reinforcing effects. However, preclinical studies have shown that with repeated drug exposure neutral stimuli paired with the drug (conditioned stimuli) start to increase dopamine by themselves, which is an effect that could underlie drug-seeking behavior. Here we test whether dopamine increases occur to conditioned stimuli in human subjects addicted to cocaine and whether this is associated with drug craving. We tested eighteen cocaine-addicted subjects using positron emission tomography and [11C]raclopride (dopamine D2 receptor radioligand sensitive to competition with endogenous dopamine). We measured changes in dopamine by comparing the specific binding of [11C]raclopride when subjects watched a neutral video (nature scenes) versus when they watched a cocaine-cue video (scenes of subjects smoking cocaine). The specific binding of [11C]raclopride in dorsal (caudate and putamen) but not in ventral striatum (in which nucleus accumbens is located) was significantly reduced in the cocaine-cue condition and the magnitude of this reduction correlated with self-reports of craving. Moreover, subjects with the highest scores on measures of withdrawal symptoms and of addiction severity that have been shown to predict treatment outcomes, had the largest dopamine changes in dorsal striatum. This provides evidence that dopamine in the dorsal striatum (region implicated in habit learning and in action initiation) is involved with craving and is a fundamental component of addiction. Because craving is a key contributor to relapse, strategies aimed at inhibiting dopamine increases from conditioned responses are likely to be therapeutically beneficial in cocaine addiction.
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| Striatal cue-reactivity and neurotransmitter function in gambling disorder. | Bellmunt-Gil A et al. | β | 2025 | β |
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| Dysregulation of dopamine neurotransmission in drug addicts: implications for criminal behavior and corrective interventions. | Gu C et al. | β | 2024 | β |
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| Mapping the Neural Substrates of Cocaine Craving: A Systematic Review. | Paludetto LS et al. | β | 2024 | β |
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| Re-evaluating our focus in addiction: emotional dysregulation is a critical driver of relapse to drug use. | Hand LJ et al. | β | 2024 | β |
| Structural brain changes associated with cocaine use and digital cognitive behavioral therapy in cocaine use disorder treatment. | McCurdy LY et al. | β | 2024 | β |
| Subregion specific neuroadaptations in the female rat striatum during acute and protracted withdrawal from nicotine. | LagstrΓΆm O et al. | β | 2024 | β |
| Temporal Dynamics of Neural Response to Drug Cues in abstinent Methamphetamine Users. | Soleymani MB et al. | β | 2024 | β |
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| Amphetamine-induced prolonged disturbances in tissue levels of dopamine and serotonin in the rat brain. | Taracha E et al. | β | 2023 | β |
| A multivariate regressor of patterned dopamine release predicts relapse to cocaine. | LujΓ‘n MΓ et al. | β | 2023 | β |
| Blunted Expected Reward Value Signals in Binge Alcohol Drinkers. | Tolomeo S et al. | β | 2023 | β |
| Brain responses to positive and negative events in individuals with internet gaming disorder during real gaming. | Zhang Z et al. | β | 2023 | β |
| cAMP-mediated upregulation of HCN channels in VTA dopamine neurons promotes cocaine reinforcement. | Mu L et al. | β | 2023 | β |
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| Negative impact of daily screen use on inhibitory control network in preadolescence: A two-year follow-up study. | Chen YY et al. | β | 2023 | β |
| Neural circuit selective for fast but not slow dopamine increases in drug reward. | Manza P et al. | β | 2023 | β |
| Neuroplastic Changes in Addiction Memory-How Music Therapy and Music-Based Intervention May Reduce Craving: A Narrative Review. | Pasqualitto F et al. | β | 2023 | β |
| Potential Biological Markers and Treatment Implications for Binge Eating Disorder and Behavioral Addictions. | Mestre-Bach G et al. | β | 2023 | β |
| Potential effect of antidepressants on remission from cocaine use disorder - A nationwide matched retrospective cohort study. | Gao Z et al. | β | 2023 | β |
| Relapse Prevention and Prediction Strategies in Substance Use Disorder: A Scoping Review. | Carter T et al. | β | 2023 | β |
| Resting-State Functional Connectivity of the Dorsal and Ventral Striatum, Impulsivity, and Severity of Use in Recently Abstinent Cocaine-Dependent Individuals. | Dong X et al. | β | 2023 | β |
| Striatal hypoactivation during monetary loss anticipation in individuals with substance use disorders in a heterogenous urban American Indian sample. | Wilhelm RA et al. | β | 2023 | β |
| Substance Use Disorders: Basic Overview for the Anesthesiologist. | Jimenez Ruiz F et al. | β | 2023 | β |
| The Role of Physical Exercise in Opioid Substitution Therapy: Mechanisms of Sequential Effects. | Psarianos A et al. | β | 2023 | β |
| The Role of Unawareness, Volition, and Neural Hyperconnectivity in Alcohol Use Disorder: A Functional Magnetic Resonance Imaging Study. | Hornoiu IL et al. | β | 2023 | β |
| The Stage-Based Model of Addiction-Using <i>Drosophila</i> to Investigate Alcohol and Psychostimulant Responses. | Cummins-Beebee PN et al. | β | 2023 | β |
| The traps of adaptation: Addiction as maladaptive referent-dependent evaluation. | Rigoli F et al. | β | 2023 | β |
| Acute and protracted abstinence from methamphetamine bidirectionally changes intrinsic excitability of indirect pathway spiny projection neurons in the dorsomedial striatum. | Choi S et al. | β | 2022 | β |
| Addiction-induced plasticity in underlying neural circuits. | Kourosh-Arami M et al. | β | 2022 | β |
| Aerobic exercise as a promising nonpharmacological therapy for the treatment of substance use disorders. | Marrero-Cristobal G et al. | β | 2022 | β |
| Alcohol reinstatement after prolonged abstinence from alcohol drinking by female adolescent rats: Roles of cyclooxygenase-2 and the prostaglandin E<sub>2</sub> receptor 1. | Kline HL et al. | β | 2022 | β |
| A methodological checklist for fMRI drug cue reactivity studies: development and expert consensus. | Ekhtiari H et al. | β | 2022 | β |
| A neuroeconomic signature of opioid craving: How fluctuations in craving bias drug-related and nondrug-related value. | Biernacki K et al. | β | 2022 | β |
| A Novel and Selective Dopamine Transporter Inhibitor, <i>(S)</i>-MK-26, Promotes Hippocampal Synaptic Plasticity and Restores Effort-Related Motivational Dysfunctions. | Kouhnavardi S et al. | β | 2022 | β |
| Assessment of motion and model bias on the detection of dopamine response to behavioral challenge. | Levine MA et al. | β | 2022 | β |
| Cocaine: An Updated Overview on Chemistry, Detection, Biokinetics, and Pharmacotoxicological Aspects including Abuse Pattern. | Roque Bravo R et al. | β | 2022 | β |
| Does stimulant drug-induced sensitization occur in primates? | Leyton M | β | 2022 | β |
| Dopamine D2 receptors bidirectionally regulate striatal enkephalin expression: Implications for cocaine reward. | Dai KZ et al. | β | 2022 | β |
| Electrophysiological signature of the interplay between habits and inhibition in response to smoking-related cues in individuals with a smoking habit: an ERP study | DampurΓ© J et al. | β | 2022 | β |
| Epac2 in midbrain dopamine neurons contributes to cocaine reinforcement via enhancement of dopamine release. | Liu X et al. | β | 2022 | β |
| Future Newborns with Opioid-Induced Neonatal Abstinence Syndrome (NAS) Could Be Assessed with the Genetic Addiction Risk Severity (GARS) Test and Potentially Treated Using Precision Amino-Acid Enkephalinase Inhibition Therapy (KB220) as a Frontline Modality Instead of Potent Opioids. | Ceccanti M et al. | β | 2022 | β |
| Intranasal oxytocin may improve odds of abstinence in cocaine-dependent patients: results from a preliminary study. | NoΓ«l Raby W et al. | β | 2022 | β |
| Is addiction a brain disease? A plea for agnosticism and heterogeneity. | Pickard H | β | 2022 | β |
| Metabolic phenotyping of opioid and psychostimulant addiction: A novel approach for biomarker discovery and biochemical understanding of the disorder. | Caspani G et al. | β | 2022 | β |
| Natural Products for the Treatment of Drug Addiction: Narrative Review. | Raslan MA | β | 2022 | β |
| Negative Urgency Exacerbates Relapse to Cocaine Seeking After Abstinence. | Fouyssac M et al. | β | 2022 | β |
| New directions in modelling dysregulated reward seeking for food and drugs. | Brown RM et al. | β | 2022 | β |
| Reciprocal modulation between cigarette smoking and internet gaming disorder on participation coefficient within functional brain networks. | Qiu X et al. | β | 2022 | β |
| Sign-tracking modulates reward-related neural activation to reward cues, but not reward feedback. | Duckworth JJ et al. | β | 2022 | β |
| Strengthened and posterior-shifted structural rich-club organization in people who use cocaine. | Hall SA et al. | β | 2022 | β |
| Trauma exposure among cannabis use disorder individuals was associated with a craving-correlated non-habituating amygdala response to aversive cues. | Regier PS et al. | β | 2022 | β |
| Using Virtual Reality to Induce and Assess Objective Correlates of Nicotine Craving: Paradigm Development Study. | Liu W et al. | β | 2022 | β |
| Acute depletion of dopamine precursors in the human brain: effects on functional connectivity and alcohol attentional bias. | Elton A et al. | β | 2021 | β |
| A salience misattribution model for addictive-like behaviors. | Kalhan S et al. | β | 2021 | β |
| Association between functional brain alterations and neuropsychological scales in male chronic smokers using resting-state fMRI. | Weng JC et al. | β | 2021 | β |
| Cocaine-related DNA methylation in caudate neurons alters 3D chromatin structure of the IRXA gene cluster. | Vaillancourt K et al. | β | 2021 | β |
| Conscious and unconscious brain responses to food and cocaine cues. | Wiers CE et al. | β | 2021 | β |
| Cortical thickness and subcortical volume abnormalities in male crack-cocaine users. | Bittencourt AML et al. | β | 2021 | β |
| Diets Varying in Carbohydrate Content Differentially Alter Brain Activity in Homeostatic and Reward Regions in Adults. | Holsen LM et al. | β | 2021 | β |
| Disruption of Cigarette Smoking Addiction After Dorsal Striatum Damage. | Jing C et al. | β | 2021 | β |
| Disruption of prepulse inhibition is associated with compulsive behavior severity and nucleus accumbens dopamine receptor changes in Sapap3 knockout mice. | Manning EE et al. | β | 2021 | β |
| Dopamine Circuit Mechanisms of Addiction-Like Behaviors. | Poisson CL et al. | β | 2021 | β |
| Dopaminergic and noradrenergic modulation of stress-induced alterations in brain activation associated with goal-directed behaviour. | van Ruitenbeek P et al. | β | 2021 | β |
| Dorsal and ventral striatal functional connectivity shifts play a potential role in internet gaming disorder. | Dong GH et al. | β | 2021 | β |
| Dorsal and ventral striatum activity in individuals with buying-shopping disorder during cue-exposure: A functional magnetic resonance imaging study. | Trotzke P et al. | β | 2021 | β |
| Dorsolateral striatum dopamine-dependent cocaine seeking is resistant to pavlovian cue extinction in male and female rats. | Bender BN et al. | β | 2021 | β |
| Egr2 induction in spiny projection neurons of the ventrolateral striatum contributes to cocaine place preference in mice. | Mukherjee D et al. | β | 2021 | β |
| Environmental Tobacco Smoke Exposure and Brain Functioning Associated with Smoking Cue-Reactivity and Inhibitory Control in Nonsmoking Adolescents. | Boormans AJMG et al. | β | 2021 | β |
| Exposure to drugs of abuse induce effects that persist across generations. | Baratta AM et al. | β | 2021 | β |
| Imbalanced sensitivities to primary and secondary rewards in internet gaming disorder. | Zhou WR et al. | β | 2021 | β |
| Incentive sensitization in binge behaviors: A mini review on electrophysiological evidence. | Werle D et al. | β | 2021 | β |
| Influence of ovarian hormones on value-based decision-making systems: Contribution to sexual dimorphisms in mental disorders. | Ambrase A et al. | β | 2021 | β |
| Inhibitory failures in cocaine use disorder: Not paying attention when there is a need to be cautious. | Howlett JR et al. | β | 2021 | β |
| Methylation of the tyrosine hydroxylase gene is dysregulated by cocaine dependence in the human striatum. | Vaillancourt K et al. | β | 2021 | β |
| Midcingulate Cortical Activations Interrelate Chronic Craving and Physiological Responses to Negative Emotions in Cocaine Addiction. | Zhornitsky S et al. | β | 2021 | β |
| Modafinil and its structural analogs as atypical dopamine uptake inhibitors and potential medications for psychostimulant use disorder. | Tanda G et al. | β | 2021 | β |
| Multimodal investigation of dopamine D<sub>2</sub>/D<sub>3</sub> receptors, default mode network suppression, and cognitive control in cocaine-use disorder. | Worhunsky PD et al. | β | 2021 | β |
| Neural Substrates and Circuits of Drug Addiction. | Feltenstein MW et al. | β | 2021 | β |
| Progress in opioid reward research: From a canonical two-neuron hypothesis to two neural circuits. | Galaj E et al. | β | 2021 | β |
| Protracted Abstinence From Extended Cocaine Self-Administration Is Associated With Hypodopaminergic Activity in the VTA but Not in the SNc. | Salin A et al. | β | 2021 | β |
| Recent Advances in In Vivo Neurochemical Monitoring. | Tan C et al. | β | 2021 | β |
| Reliability assessment of temporal discounting measures in virtual reality environments. | Bruder LR et al. | β | 2021 | β |
| Reward-Related Responses and Tonic Craving in Cocaine Addiction: An Imaging Study of the Monetary Incentive Delay Task. | Zhornitsky S et al. | β | 2021 | β |
| Sleep and Memory Consolidation Dysfunction in Psychiatric Disorders: Evidence for the Involvement of Extracellular Matrix Molecules. | Gisabella B et al. | β | 2021 | β |
| Smoking-induced craving relief relates to increased DLPFC-striatal coupling in nicotine-dependent women. | Franklin TR et al. | β | 2021 | β |
| Striatal transcriptome changes linked to drug-induced repetitive behaviors. | Crittenden JR et al. | β | 2021 | β |
| Sustained brain response to repeated drug cues is associated with poor drug-use outcomes. | Regier PS et al. | β | 2021 | β |
| The Higher Parietal Cortical Thickness in Abstinent Methamphetamine Patients Is Correlated With Functional Connectivity and Age of First Usage. | Yang R et al. | β | 2021 | β |
| The influence of conditioned stimuli on [<sup>11</sup>C]-(+)-PHNO PET binding in tobacco smokers after a one week abstinence. | Di Ciano P et al. | β | 2021 | β |
| The neuroscience of unmet social needs. | Tomova L et al. | β | 2021 | β |
| The role of serotoninergic system in psychostimulant effects. | Taracha E | β | 2021 | β |
| The role of withdrawal in mesocorticolimbic drug cue reactivity in opioid use disorder. | Shi Z et al. | β | 2021 | β |
| Whole-Brain Mapping of Direct Inputs to Dopamine D1 and D2 Receptor-Expressing Medium Spiny Neurons in the Posterior Dorsomedial Striatum. | Lu J et al. | β | 2021 | β |
| Accelerated development of cocaine-associated dopamine transients and cocaine use vulnerability following traumatic stress. | Brodnik ZD et al. | β | 2020 | β |
| Acetylcholine Muscarinic M<sub>4</sub> Receptors as a Therapeutic Target for Alcohol Use Disorder: Converging Evidence From Humans and Rodents. | Walker LC et al. | β | 2020 | β |
| Brain-gut-microbiome interactions in obesity and food addiction. | Gupta A et al. | β | 2020 | β |
| Caudate reactivity to smoking cues is associated with increased responding to monetary reward in nicotine-dependent individuals. | Molokotos E et al. | β | 2020 | β |
| Clinical Trials for Stimulant Use Disorders: Addressing Heterogeneities That May Undermine Treatment Outcomes. | Regier PS et al. | β | 2020 | β |
| Effects of brief inhibition of the ventral tegmental area dopamine neurons on the cocaine seeking during abstinence. | Solecki W et al. | β | 2020 | β |
| Effects of dose on acquisition and persistence of a new response for a remifentanil-associated stimulus. | Robertson SH et al. | β | 2020 | β |
| Effects of long-term cocaine self-administration on brain resting-state functional connectivity in nonhuman primates. | Kohut SJ et al. | β | 2020 | β |
| Electrical Stimulation Evokes Rotational Behavior In Tandem with Exocytotic-like Increases in Dopamine Measured by In Vivo Intracerebral Microdialysis. | Grant AH et al. | β | 2020 | β |
| From sign-tracking to attentional bias: Implications for gambling and substance use disorders. | Anselme P et al. | β | 2020 | β |
| Glycogen synthase kinase-3 signaling in cellular and behavioral responses to psychostimulant drugs. | Barr JL et al. | β | 2020 | β |
| Health and economic outcomes of treatment with extended-release naltrexone among pre-release prisoners with opioid use disorder (HOPPER): protocol for an evaluation of two randomized effectiveness trials. | Murphy SM et al. | β | 2020 | β |
| How the harm of drugs and their availability affect brain reactions to drug cues: a meta-analysis of 64 neuroimaging activation studies. | Devoto F et al. | β | 2020 | β |
| Insights to the neural response to food cues in class III compared with class I and II obese adults using a sample of endometrial cancer survivors seeking weight loss. | Nock NL et al. | β | 2020 | β |
| Is craving a risk factor for substance use among treatment-seeking individuals with alcohol and other drugs use disorders? A meta-analytic review. | Cavicchioli M et al. | β | 2020 | β |
| Is it worth the effort? | Janes AC | β | 2020 | β |
| Mitigation of cocaine-mediated mitochondrial damage, defective mitophagy and microglial activation by superoxide dismutase mimetics. | Thangaraj A et al. | β | 2020 | β |
| Network failures: When incentives trigger impulsive responses. | Zhukovsky P et al. | β | 2020 | β |
| Non-pharmacological factors that determine drug use and addiction. | Ahmed SH et al. | β | 2020 | β |
| Orbitofrontal, dorsal striatum, and habenula functional connectivity in psychiatric patients with substance use problems. | Oh H et al. | β | 2020 | β |
| rTMS-Induced Changes in Glutamatergic and Dopaminergic Systems: Relevance to Cocaine and Methamphetamine Use Disorders. | Moretti J et al. | β | 2020 | β |
| Stress-related suppression of peripheral cytokines predicts future relapse in alcohol-dependent individuals with and without subclinical depression. | Fox HC et al. | β | 2020 | β |
| Striatal functional connectivity in chronic ketamine users: a pilot study. | Hung CC et al. | β | 2020 | β |
| The effect of tai chi and Qigong exercise on depression and anxiety of individuals with substance use disorders: a systematic review and meta-analysis. | Liu F et al. | β | 2020 | β |
| The transition to compulsion in addiction. | LΓΌscher C et al. | β | 2020 | β |
| This is your teen brain on drugs: In search of biological factors unique to dependence toxicity in adolescence. | Kwan LY et al. | β | 2020 | β |
| Translational study of the whole transcriptome in rats and genetic polymorphisms in humans identifies LRP1B and VPS13A as key genes involved in tolerance to cocaine-induced motor disturbances. | Vorspan F et al. | β | 2020 | β |
| Unmasking neurobiological commonalities between addictive disorders and impulse control disorders in Parkinson's disease. | Ramdave S et al. | β | 2020 | β |
| A cholecystokinin B receptor antagonist and cocaine interaction, phase I study. | Elkashef A et al. | β | 2019 | β |
| Appetitive to aversive counter-conditioning as intervention to reduce reinstatement of reward-seeking behavior: the role of the serotonin transporter. | Karel P et al. | β | 2019 | β |
| Brain default-mode network dysfunction in addiction. | Zhang R et al. | β | 2019 | β |
| Brain Function Network and Young Adult Smokers: A Graph Theory Analysis Study. | Tan Y et al. | β | 2019 | β |
| Brain Gray Matter Volume and Functional Connectivity Are Associated With Smoking Cessation Outcomes. | Qian W et al. | β | 2019 | β |
| Cholinergic Receptor Blockade in the VTA Attenuates Cue-Induced Cocaine-Seeking and Reverses the Anxiogenic Effects of Forced Abstinence. | Nunes EJ et al. | β | 2019 | β |
| Closed-Loop Implantable Therapeutic Neuromodulation Systems Based on Neurochemical Monitoring. | Mirza KB et al. | β | 2019 | β |
| Compulsive Alcohol Seeking Results from a Failure to Disengage Dorsolateral Striatal Control over Behavior. | Giuliano C et al. | β | 2019 | β |
| Cued for risk: Evidence for an incentive sensitization framework to explain the interplay between stress and anxiety, substance abuse, and reward uncertainty in disordered gambling behavior. | Hellberg SN et al. | β | 2019 | β |
| Cue Reactivity in the Ventral Striatum Characterizes Heavy Cannabis Use, Whereas Reactivity in the Dorsal Striatum Mediates Dependent Use. | Zhou X et al. | β | 2019 | β |
| D1 receptor hypersensitivity in mice with low striatal D2 receptors facilitates select cocaine behaviors. | Dobbs LK et al. | β | 2019 | β |
| Differential effects of psychoactive substances on human wildtype and polymorphic T356M dopamine transporters (DAT). | Zwartsen A et al. | β | 2019 | β |
| Dopamine and addiction: what have we learned from 40Β years of research. | Solinas M et al. | β | 2019 | β |
| Dorsolateral striatal miR-134 modulates excessive methamphetamine intake in self-administering rats. | Shi JJ et al. | β | 2019 | β |
| DRD2 promoter methylation and measures of alcohol reward: functional activation of reward circuits and clinical severity. | Bidwell LC et al. | β | 2019 | β |
| Drug-Induced Craving for Methamphetamine Is Associated With Neural Methamphetamine Cue Reactivity. | Grodin EN et al. | β | 2019 | β |
| Drug-related Virtual Reality Cue Reactivity is Associated with Gamma Activity in Reward and Executive Control Circuit in Methamphetamine UseΒ Disorders. | Tan H et al. | β | 2019 | β |
| Dynamic Causal Modeling of Insular, Striatal, and Prefrontal Cortex Activities During a Food-Specific Go/NoGo Task. | He Q et al. | β | 2019 | β |
| Effects of familial risk and stimulant drug use on the anticipation of monetary reward: an fMRI study. | Just AL et al. | β | 2019 | β |
| Exploratory locomotion, a predictor of addiction vulnerability, is oligogenic in rats selected for this phenotype. | Zhou Z et al. | β | 2019 | β |
| Food cue reactivity in food addiction: A functional magnetic resonance imaging study. | Schulte EM et al. | β | 2019 | β |
| Glutaminergic signaling in the caudate nucleus is required for behavioral sensitization to methylphenidate. | King N et al. | β | 2019 | β |
| Heroin seeking becomes dependent on dorsal striatal dopaminergic mechanisms and can be decreased by N-acetylcysteine. | Hodebourg R et al. | β | 2019 | β |
| Hippocampal BDNF regulates a shift from flexible, goal-directed to habit memory system function following cocaine abstinence. | Harvey E et al. | β | 2019 | β |
| Impulse control disorders in Parkinson's disease: A systematic review on risk factors and pathophysiology. | Latella D et al. | β | 2019 | β |
| Incubation of feeding behavior is regulated by neuromedin U receptor 2 in the paraventricular nucleus of the hypothalamus. | McCue DL et al. | β | 2019 | β |
| Menstrual cycle phase modulates responses to smoking cues in the putamen: Preliminary evidence for a novel target. | Franklin TR et al. | β | 2019 | β |
| Modulatory effects of cannabinoids on brain neurotransmission. | Cohen K et al. | β | 2019 | β |
| Molecular Adaptations in the Rat Dorsal Striatum and Hippocampus Following Abstinence-Induced Incubation of Drug Seeking After Escalated Oxycodone Self-Administration. | Blackwood CA et al. | β | 2019 | β |
| Neurocircuitry of Reward and Addiction: Potential Impact of Dopamine-Glutamate Co-release as Future Target in Substance Use Disorder. | Bimpisidis Z et al. | β | 2019 | β |
| Optogenetic control of alcohol-seeking behavior via the dorsomedial striatal circuit. | Roltsch Hellard E et al. | β | 2019 | β |
| Regulation of Brain DNA Methylation Factors and of the Orexinergic System by Cocaine and Food Self-Administration. | Saad L et al. | β | 2019 | β |
| Shared Behavioral and Neurocircuitry Disruptions in Drug Addiction, Obesity, and Binge Eating Disorder: Focus on Group I mGluRs in the Mesolimbic Dopamine Pathway. | Yohn SE et al. | β | 2019 | β |
| State-Dependent Effects of Ventromedial Prefrontal Cortex Continuous Thetaburst Stimulation on Cocaine Cue Reactivity in Chronic Cocaine Users. | Kearney-Ramos TE et al. | β | 2019 | β |
| Sucrose intake lowers ΞΌ-opioid and dopamine D2/3 receptor availability in porcine brain. | Winterdahl M et al. | β | 2019 | β |
| Systemic oxytocin administration alters mesolimbic dopamine release in mice. | Estes MK et al. | β | 2019 | β |
| The Attentional Bias in Current and Former Smokers. | Masiero M et al. | β | 2019 | β |
| The circadian gene, Per2, influences methamphetamine sensitization and reward through the dopaminergic system in the striatum of mice. | Kim M et al. | β | 2019 | β |
| The Neuroscience of Drug Reward and Addiction. | Volkow ND et al. | β | 2019 | β |
| Validation of a substance craving questionnaire (SCQ) in Italian population. | Bonfiglio NS et al. | β | 2019 | β |
| Voluntary Ethanol Intake Produces Subregion-Specific Neuroadaptations in Striatal and Cortical Areas of Wistar Rats. | LagstrΓΆm O et al. | β | 2019 | β |
| Why Do Most Restrained Eaters Fail in Losing Weight?: Evidence from an fMRI Study. | Su Y et al. | β | 2019 | β |
| Women at Greater Sexual Risk for STIs/HIV Have a Lower Mesolimbic and Affective Bias Response to Sexual Stimuli. | Regier PS et al. | β | 2019 | β |
| 21st century neurobehavioral theories of decision making in addiction: Review and evaluation. | Bickel WK et al. | β | 2018 | β |
| Addictive behaviour in experimental animals: prospects for translation. | Everitt BJ et al. | β | 2018 | β |
| Alteration of Brain Structure With Long-Term Abstinence of Methamphetamine by Voxel-Based Morphometry. | Zhang Z et al. | β | 2018 | β |
| A preliminary randomized clinical trial of naltrexone reduces striatal resting state functional connectivity in people with methamphetamine use disorder. | Kohno M et al. | β | 2018 | β |
| Are Cocaine-Seeking "Habits" Necessary for the Development of Addiction-Like Behavior in Rats? | Singer BF et al. | β | 2018 | β |
| Association of Neural Responses to Drug Cues With Subsequent Relapse to Stimulant Use. | MacNiven KH et al. | β | 2018 | β |
| A Systematic Review of Physical Activity Interventions in Individuals with Binge Eating Disorders. | Blanchet C et al. | β | 2018 | β |
| Caudate nucleus neurons participate in methylphenidate function: Behavioral and neuronal recordings from freely behaving adolescent rats. | Karim TJ et al. | β | 2018 | β |
| Complex Control of Striatal Neurotransmission by Nicotinic Acetylcholine Receptors via Excitatory Inputs onto Medium Spiny Neurons. | Licheri V et al. | β | 2018 | β |
| COMT Inhibition Alters Cue-Evoked Oscillatory Dynamics during Alcohol Drinking in the Rat. | McCane AM et al. | β | 2018 | β |
| Cue reactivity and opioid blockade in amphetamine dependence: A randomized, controlled fMRI study. | Guterstam J et al. | β | 2018 | β |
| Drug Cues, Conditioned Reinforcement, and Drug Seeking: The Sequelae of a Collaborative Venture With Athina Markou. | Everitt BJ | β | 2018 | β |
| Effects of extended-release naltrexone on the brain response to drug-related stimuli in patients with opioid use disorder. | Shi Z et al. | β | 2018 | β |
| Mindfulness meditation in the treatment of substance use disorders and preventing future relapse: neurocognitive mechanisms and clinical implications. | Priddy SE et al. | β | 2018 | β |
| Modulating musical reward sensitivity up and down with transcranial magnetic stimulation. | Mas-Herrero E et al. | β | 2018 | β |
| Neural underpinnings of maladaptive decision-making in addictions. | Guttman Z et al. | β | 2018 | β |
| Neuroscience of Addiction: Relevance to Prevention and Treatment. | Volkow ND et al. | β | 2018 | β |
| Nucleus Accumbens Modulation in Reward and Aversion. | Klawonn AM et al. | β | 2018 | β |
| Oscillatory local field potentials of the nucleus accumbens and the anterior limb of the internal capsule in heroin addicts. | Ge S et al. | β | 2018 | β |
| Oxytocin and opioid addiction revisited: old drug, new applications. | Zanos P et al. | β | 2018 | β |
| Reconsolidation blockade for the treatment of addiction: challenges, new targets, and opportunities. | Exton-McGuinness MTJ et al. | β | 2018 | β |
| Risperidone versus other antipsychotics for people with severe mental illness and co-occurring substance misuse. | Temmingh HS et al. | β | 2018 | β |
| Self-regulation of the dopaminergic reward circuit in cocaine users with mental imagery and neurofeedback. | Kirschner M et al. | β | 2018 | β |
| Sex differences after chronic stress in the expression of opioid-, stress- and neuroplasticity-related genes in the rat hippocampus. | Randesi M et al. | β | 2018 | β |
| Sex Differences in the Rat Hippocampal Opioid System After Oxycodone Conditioned Place Preference. | Ryan JD et al. | β | 2018 | β |
| Sex Differences in the Subcellular Distribution of Corticotropin-Releasing Factor Receptor 1 in the Rat Hippocampus following Chronic Immobilization Stress. | McAlinn HR et al. | β | 2018 | β |
| Small RNA-Seq reveals novel miRNAs shaping the transcriptomic identity of rat brain structures. | Soula A et al. | β | 2018 | β |
| Systemic neurotransmitter responses to clinically approved and experimental neuropsychiatric drugs. | Noori HR et al. | β | 2018 | β |
| The Affective and Neural Correlates of Heroin versus Cocaine Use in Addiction Are Influenced by Environmental Setting But in Opposite Directions. | De Pirro S et al. | β | 2018 | β |
| The computational form of craving is a selective multiplication of economic value. | Konova AB et al. | β | 2018 | β |
| The Effects of the Monoamine Stabilizer (-)-OSU6162 on Binge-Like Eating and Cue-Controlled Food-Seeking Behavior in Rats. | Feltmann K et al. | β | 2018 | β |
| Accumbens volumes are reduced among crack-cocaine users. | Schuch-Goi SB et al. | β | 2017 | β |
| Activation of the ventral and dorsal striatum during cue reactivity in Internet gaming disorder. | Liu L et al. | β | 2017 | β |
| A hypo-status in drug-dependent brain revealed by multi-modal MRI. | Wang Z et al. | β | 2017 | β |
| Altered resting state functional connectivity of anterior insula in young smokers. | Bi Y et al. | β | 2017 | β |
| Altered spontaneous brain activity in chronic smokers revealed by fractional ramplitude of low-frequency fluctuation analysis: a preliminary study. | Wang C et al. | β | 2017 | β |
| Altered thalamo-cortical resting state functional connectivity in smokers. | Wang C et al. | β | 2017 | β |
| A method for evaluating cocaine-induced social preference in rats. | Dingess PM et al. | β | 2017 | β |
| A neuronal activation correlate in striatum and prefrontal cortex of prolonged cocaine intake. | Gao P et al. | β | 2017 | β |
| A review of positron emission tomography studies exploring the dopaminergic system in substance use with a focus on tobacco as a co-variate. | Thiruchselvam T et al. | β | 2017 | β |
| Association of Stimulant Use With Dopaminergic Alterations in Users of Cocaine, Amphetamine, or Methamphetamine: A Systematic Review and Meta-analysis. | Ashok AH et al. | β | 2017 | β |
| Behavioral and transcriptional patterns of protracted opioid self-administration in mice. | Skupio U et al. | β | 2017 | β |
| Blunted Dopamine Transmission in Addiction: Potential Mechanisms and Implications for Behavior. | Trifilieff P et al. | β | 2017 | β |
| Brain-derived neurotrophic factor downregulates immunoglobulin heavy chain binding protein expression after repeated cocaine administration in the rat dorsal striatum. | Kim J et al. | β | 2017 | β |
| Brain reactivity to alcohol and cannabis marketing during sobriety and intoxication. | de Sousa Fernandes Perna EB et al. | β | 2017 | β |
| Cocaine Cue-Induced Dopamine Release in Recreational Cocaine Users. | Cox SML et al. | β | 2017 | β |
| Cocaine sensitization increases subthreshold activity in dopamine neurons from the ventral tegmental area. | Arencibia-Albite F et al. | β | 2017 | β |
| Color vision predicts processing modes of goal activation during action cascading. | Jongkees BJ et al. | β | 2017 | β |
| Distinct Synaptic Strengthening of the Striatal Direct and Indirect Pathways Drives Alcohol Consumption. | Cheng Y et al. | β | 2017 | β |
| Effects of 5-HT<sub>1A</sub>, 5-HT<sub>2A</sub> and 5-HT<sub>2C</sub> receptor agonists and antagonists on responding for a conditioned reinforcer and its enhancement by methylphenidate. | Fletcher PJ et al. | β | 2017 | β |
| Effects of diet and insulin on dopamine transporter activity and expression in rat caudate-putamen, nucleus accumbens, and midbrain. | Jones KT et al. | β | 2017 | β |
| Emotional, physical and sexual abuse are associated with a heightened limbic response to cocaine cues. | Regier PS et al. | β | 2017 | β |
| Food-Predicting Stimuli Differentially Influence Eye Movements and Goal-Directed Behavior in Normal-Weight, Overweight, and Obese Individuals. | Lehner R et al. | β | 2017 | β |
| Granger causality reveals a dominant role of memory circuit in chronic opioid dependence. | Zhang Y et al. | β | 2017 | β |
| Impulse Control and Related Disorders in Parkinson's Disease. | Weintraub D et al. | β | 2017 | β |
| Impulse Control Disorders and Related Complications of Parkinson's Disease Therapy. | Lopez AM et al. | β | 2017 | β |
| Individual differences in the neuropsychopathology of addiction. | George O et al. | β | 2017 | β |
| Influences of Dietary Added Sugar Consumption on Striatal Food-Cue Reactivity and Postprandial GLP-1 Response. | Dorton HM et al. | β | 2017 | β |
| Learning and generalization from reward and punishment in opioid addiction. | Myers CE et al. | β | 2017 | β |
| Linking dopaminergic reward signals to the development of attentional bias: A positron emission tomographic study. | Anderson BA et al. | β | 2017 | β |
| Medications for substance use disorders (SUD): emerging approaches. | Butelman ER et al. | β | 2017 | β |
| Memory-focused cognitive therapy for cocaine use disorder: Rationale, design and protocol for an external pilot randomised controlled trial. | Marsden J et al. | β | 2017 | β |
| Morphine Reward Promotes Cue-Sensitive Learning: Implication of Dorsal Striatal CREB Activity. | Baudonnat M et al. | β | 2017 | β |
| Naltrexone moderates the relationship between cue-induced craving and subjective response to methamphetamine in individuals with methamphetamine use disorder. | Roche DJO et al. | β | 2017 | β |
| Naltrexone modulates dopamine release following chronic, but not acute amphetamine administration: a translational study. | Jayaram-LindstrΓΆm N et al. | β | 2017 | β |
| Neural correlates of 12-h abstinence-induced craving in young adult smokers: a resting-state study. | Li Y et al. | β | 2017 | β |
| Neuromodulation interventions for addictive disorders: challenges, promise, and roadmap for future research. | Spagnolo PA et al. | β | 2017 | β |
| News Feature: Is video game addiction really an addiction? | Zastrow M | β | 2017 | β |
| Prolonged Induction of miR-212/132 and REST Expression in Rat Striatum Following Cocaine Self-Administration. | Sadakierska-Chudy A et al. | β | 2017 | β |
| Received View of Addiction, Relapse and Treatment. | Ndasauka Y et al. | β | 2017 | β |
| Recent Developments in Psychopharmaceutical Approaches to Treating Female Sexual Interest and Arousal Disorder. | Both S | β | 2017 | β |
| Reward Prediction Errors in Drug Addiction and Parkinson's Disease: from Neurophysiology to Neuroimaging. | GarcΓa-GarcΓa I et al. | β | 2017 | β |
| Role of impulsivity and reward in the anti-obesity actions of 5-HT<sub>2C</sub> receptor agonists. | Higgins GA et al. | β | 2017 | β |
| Sensitive periods of substance abuse: Early risk for the transition to dependence. | Jordan CJ et al. | β | 2017 | β |
| Sex differences, gender and addiction. | Becker JB et al. | β | 2017 | β |
| The cerebellum in drug craving. | Moreno-Rius J et al. | β | 2017 | β |
| The effects of d-govadine on conditioned place preference with d-amphetamine or food reward. | Nesbit MO et al. | β | 2017 | β |
| The genetic epidemiology of substance use disorder: A review. | Prom-Wormley EC et al. | β | 2017 | β |
| The left dorsolateral prefrontal cortex and caudate pathway: New evidence for cue-induced craving of smokers. | Yuan K et al. | β | 2017 | β |
| Ventral and Dorsal Striatum Networks in Obesity: Link to Food Craving and Weight Gain. | Contreras-RodrΓguez O et al. | β | 2017 | β |
| Abuse potential and dopaminergic effect of alkyl nitrites. | Jeon SY et al. | β | 2016 | β |
| Acquisition of Conditioned Responses to a Novel Alcohol-Paired Cue in Social Drinkers. | Mayo LM et al. | β | 2016 | β |
| Acquisition of Conditioning between Methamphetamine and Cues in Healthy Humans. | Cavallo JS et al. | β | 2016 | β |
| Addiction: From Context-Induced Hedonia to Appetite, Based on Transition of Micro-behaviors in Morphine Abstinent Tree Shrews. | Duan Y et al. | β | 2016 | β |
| Addictions Neuroclinical Assessment: A Neuroscience-Based Framework for Addictive Disorders. | Kwako LE et al. | β | 2016 | β |
| Altered resting-state functional connectivity of the insula in young adults with Internet gaming disorder. | Zhang JT et al. | β | 2016 | β |
| Altered Spontaneous Brain Activity in Betel Quid Dependence: A Resting-state Functional Magnetic Resonance Imaging Study. | Liu T et al. | β | 2016 | β |
| A review of gambling disorder and substance use disorders. | Rash CJ et al. | β | 2016 | β |
| Are We Moving Closer to Noninvasive Imaging and Monitoring of Neonatal Anesthesia-induced Neurotoxicity? | Benveniste H et al. | β | 2016 | β |
| A selective D3 receptor antagonist YQA14 attenuates methamphetamine-induced behavioral sensitization and conditioned place preference in mice. | Sun L et al. | β | 2016 | β |
| BAS-drive trait modulates dorsomedial striatum activity during reward response-outcome associations. | Costumero V et al. | β | 2016 | β |
| Brain Activity During Cocaine Craving and Gambling Urges: An fMRI Study. | Kober H et al. | β | 2016 | β |
| Cocaine cue-induced dopamine release in the human prefrontal cortex. | Milella MS et al. | β | 2016 | β |
| Common Brain Mechanisms of Chronic Pain and Addiction. | Elman I et al. | β | 2016 | β |
| Considerations in the Evaluation of Potential Efficacy of Medications for Alcohol and Drug Use Disorders: An Editorial. | Egli M et al. | β | 2016 | β |
| Counter striking psychosis: Commercial video games as potential treatment in schizophrenia? A systematic review of neuroimaging studies. | Suenderhauf C et al. | β | 2016 | β |
| Differences in IV alcohol-induced dopamine release in the ventral striatum of social drinkers and nontreatment-seeking alcoholics. | Yoder KK et al. | β | 2016 | β |
| Disrupting GluA2 phosphorylation potentiates reinstatement of cocaine seeking. | Briand LA et al. | β | 2016 | β |
| Dopamine D3 Receptor Antagonists as Potential Therapeutics for the Treatment of Neurological Diseases. | Maramai S et al. | β | 2016 | β |
| Dopamine Transporter Correlates and Occupancy by Modafinil in Cocaine-Dependent Patients: A Controlled Study With High-Resolution PET and [(11)C]-PE2I. | Karila L et al. | β | 2016 | β |
| Drug Addiction: Updating Actions to Habits to Compulsions Ten Years On. | Everitt BJ et al. | β | 2016 | β |
| Eating behavior associated with gray matter volume alternations: A voxel based morphometry study. | Yao L et al. | β | 2016 | β |
| Effective Connectivity within the Mesocorticolimbic System during Resting-State in Cocaine Users. | Ray S et al. | β | 2016 | β |
| Extinction of Conditioned Responses to Methamphetamine-Associated Stimuli in Healthy Humans. | Cavallo JS et al. | β | 2016 | β |
| Glutamatergic and neurometabolic alterations in chronic cocaine users measured with (1) H-magnetic resonance spectroscopy. | Hulka LM et al. | β | 2016 | β |
| Habit formation coincides with shifts in reinforcement representations in the sensorimotor striatum. | Smith KS et al. | β | 2016 | β |
| In search of anticipatory cigarette cravings: The impact of perceived smoking opportunity and motivation to seek treatment. | Sayette MA et al. | β | 2016 | β |
| Intranasal oxytocin dampens cue-elicited cigarette craving in daily smokers: a pilot study. | Miller MA et al. | β | 2016 | β |
| Involvement of dorsal striatal Ξ±1-containing GABAA receptors in methamphetamine-associated rewarding memories. | Jiao DL et al. | β | 2016 | β |
| Jumping to conclusions in untreated patients with Parkinson's disease. | de Rezende Costa FH et al. | β | 2016 | β |
| Low Impulsive Action, but not Impulsive Choice, Predicts Greater Conditioned Reinforcer Salience and Augmented Nucleus Accumbens Dopamine Release. | Zeeb FD et al. | β | 2016 | β |
| Mephedrone and 3,4-methylenedioxy-methamphetamine: Comparative psychobiological effects as reported by recreational polydrug users. | Jones L et al. | β | 2016 | β |
| Negative association of pretreatment cigarette use with smoking-induced striatal dopamine release in smokers receiving bupropion treatment. | Weinstein AM et al. | β | 2016 | β |
| Network-Based Analysis Reveals Functional Connectivity Related to Internet Addiction Tendency. | Wen T et al. | β | 2016 | β |
| Neurobiologic Advances from the Brain Disease Model of Addiction. | Volkow ND et al. | β | 2016 | β |
| Neurobiology of addiction: a neurocircuitry analysis. | Koob GF et al. | β | 2016 | β |
| Neurofunctional Reward Processing Changes in Cocaine Dependence During Recovery. | Balodis IM et al. | β | 2016 | β |
| Neuroscience of drug craving for addiction medicine: From circuits to therapies. | Ekhtiari H et al. | β | 2016 | β |
| Oxytocin for the treatment of drug and alcohol use disorders. | Lee MR et al. | β | 2016 | β |
| Post-cocaine changes in regulator of G-protein signaling (RGS) proteins in the dorsal striatum: Relevance for cocaine-seeking and protein kinase C-mediated phosphorylation. | Bilodeau J et al. | β | 2016 | β |
| Prause et al. (2015) the latest falsification of addiction predictions. | Prause N et al. | β | 2016 | β |
| Regional homogeneity changes between heroin relapse and non-relapse patients under methadone maintenance treatment: a resting-state fMRI study. | Chang H et al. | β | 2016 | β |
| Reward Contingencies Improve Goal-Directed Behavior by Enhancing Posterior Brain Attentional Regions and Increasing Corticostriatal Connectivity in Cocaine Addicts. | Rosell-Negre P et al. | β | 2016 | β |
| Romantic Love vs. Drug Addiction May Inspire a New Treatment for Addiction. | Zou Z et al. | β | 2016 | β |
| Sex differences in reinstatement of cocaine-seeking with combination treatments of progesterone and atomoxetine. | Swalve N et al. | β | 2016 | β |
| Sex differences in subcellular distribution of delta opioid receptors in the rat hippocampus in response to acute and chronic stress. | Mazid S et al. | β | 2016 | β |
| Shared and unique mechanisms underlying binge eating disorder and addictive disorders. | Schulte EM et al. | β | 2016 | β |
| Strain and cocaine-induced differential opioid gene expression may predispose Lewis but not Fischer rats to escalate cocaine self-administration. | Valenza M et al. | β | 2016 | β |
| Targeting the Oxytocin System to Treat Addictive Disorders: Rationale and Progress to Date. | Lee MR et al. | β | 2016 | β |
| Temporal Rewiring of Striatal Circuits Initiated by Nicotine. | Adermark L et al. | β | 2016 | β |
| The attention habit: how reward learning shapes attentional selection. | Anderson BA | β | 2016 | β |
| The Effects of Pharmacological Opioid Blockade on Neural Measures of Drug Cue-Reactivity in Humans. | Courtney KE et al. | β | 2016 | β |
| The motor way: Clinical implications of understanding and shaping actions with the motor system in autism and drug addiction. | Casartelli L et al. | β | 2016 | β |
| The Role of Dopamine in Value-Based Attentional Orienting. | Anderson BA et al. | β | 2016 | β |
| Topiramate for cocaine dependence: a systematic review and meta-analysis of randomized controlled trials. | Singh M et al. | β | 2016 | β |
| What is abnormal about addiction-related attentional biases? | Anderson BA | β | 2016 | β |
| Abnormal frontostriatal activity in recently abstinent cocaine users during implicit moral processing. | Caldwell BM et al. | β | 2015 | β |
| Activity-regulated gene expression in immature neurons in the dentate gyrus following re-exposure to a cocaine-paired environment. | Barr JL et al. | β | 2015 | β |
| Adaptations of presynaptic dopamine terminals induced by psychostimulant self-administration. | Siciliano CA et al. | β | 2015 | β |
| A hyper-connected but less efficient small-world network in the substance-dependent brain. | Wang Z et al. | β | 2015 | β |
| A Role for p38 Mitogen-activated Protein Kinase-mediated Threonine 30-dependent Norepinephrine Transporter Regulation in Cocaine Sensitization and Conditioned Place Preference. | Mannangatti P et al. | β | 2015 | β |
| Assessment of Pharmacokinetic and Pharmacodynamic Interactions Between Albumin-Fused Mutated Butyrylcholinesterase and Intravenously Administered Cocaine in Recreational Cocaine Users. | Shram MJ et al. | β | 2015 | β |
| Basal ganglia circuit loops, dopamine and motivation: A review and enquiry. | Ikemoto S et al. | β | 2015 | β |
| Basolateral and central amygdala differentially recruit and maintain dorsolateral striatum-dependent cocaine-seeking habits. | Murray JE et al. | β | 2015 | β |
| Boundary conditions of methamphetamine craving. | Lopez RB et al. | β | 2015 | β |
| Chronic alcohol intake abolishes the relationship between dopamine synthesis capacity and learning signals in the ventral striatum. | Deserno L et al. | β | 2015 | β |
| Cocaine choice procedures in animals, humans, and treatment-seekers: Can we bridge the divide? | Moeller SJ et al. | β | 2015 | β |
| Cocaine-conditioned odor cues without chronic exposure: Implications for the development of addiction vulnerability. | Lowen SB et al. | β | 2015 | β |
| Cocaine self-administration disrupts mesolimbic dopamine circuit function and attenuates dopaminergic responsiveness to cocaine. | Siciliano CA et al. | β | 2015 | β |
| Craving and substance use among patients with alcohol, tobacco, cannabis or heroin addiction: a comparison of substance- and person-specific cues. | Fatseas M et al. | β | 2015 | β |
| Cue-induced craving in patients with cocaine use disorder predicts cognitive control deficits toward cocaine cues. | DiGirolamo GJ et al. | β | 2015 | β |
| Deep Brain Stimulation for Obesity. | Ho AL et al. | β | 2015 | β |
| Deep brain stimulation for obesity: rationale and approach to trial design. | Ho AL et al. | β | 2015 | β |
| Determinants of conditioned reinforcing effectiveness: Dopamine D2-like receptor agonist-stimulated responding for cocaine-associated stimuli. | Collins GT et al. | β | 2015 | β |
| Dopamine agonists for the treatment of cocaine dependence. | Minozzi S et al. | β | 2015 | β |
| Dopamine D1 receptor blockade impairs alcohol seeking without reducing dorsal striatal activation to cues of alcohol availability. | Fanelli RR et al. | β | 2015 | β |
| Dopamine D4 receptors linked to protein kinase G are required for changes in dopamine release followed by locomotor activity after repeated cocaine administration. | Oh JH et al. | β | 2015 | β |
| Dopamine Prediction Errors in Reward Learning and Addiction: From Theory to Neural Circuitry. | Keiflin R et al. | β | 2015 | β |
| Dopaminergic basis for impairments in functional connectivity across subdivisions of the striatum in Parkinson's disease. | Bell PT et al. | β | 2015 | β |
| Dopaminergic Regulation of Striatal Interneurons in Reward and Addiction: Focus on Alcohol. | Clarke R et al. | β | 2015 | β |
| Dorsal medial prefrontal cortex (MPFC) circuitry in rodent models of cocaine use: implications for drug addiction therapies. | Jasinska AJ et al. | β | 2015 | β |
| Effects of adolescent caffeine consumption on cocaine sensitivity. | O'Neill CE et al. | β | 2015 | β |
| Effects of context-drug learning on synaptic connectivity in the basolateral nucleus of the amygdala in rats. | Rademacher DJ et al. | β | 2015 | β |
| Effects of social sustainability signaling on neural valuation signals and taste-experience of food products. | Enax L et al. | β | 2015 | β |
| Electrophysiological evidence of alterations to the nucleus accumbens and dorsolateral striatum during chronic cocaine self-administration. | Coffey KR et al. | β | 2015 | β |
| Female adolescents with severe substance and conduct problems have substantially less brain gray matter volume. | Dalwani MS et al. | β | 2015 | β |
| Genetic Similarities between Compulsive Overeating and Addiction Phenotypes: A Case for "Food Addiction"? | Carlier N et al. | β | 2015 | β |
| Gray-matter volume, midbrain dopamine D2/D3 receptors and drug craving in methamphetamine users. | Morales AM et al. | β | 2015 | β |
| Hypoactivation of the ventral and dorsal striatum during reward and loss anticipation in antipsychotic and mood stabilizer-naive bipolar disorder. | Yip SW et al. | β | 2015 | β |
| Increased adult hippocampal neurogenesis is not necessary for wheel running to abolish conditioned place preference for cocaine in mice. | Mustroph ML et al. | β | 2015 | β |
| Influence of dorsolateral prefrontal cortex and ventral striatum on risk avoidance in addiction: a mediation analysis. | Yamamoto DJ et al. | β | 2015 | β |
| Insula-Dorsal Anterior Cingulate Cortex Coupling is Associated with Enhanced Brain Reactivity to Smoking Cues. | Janes AC et al. | β | 2015 | β |
| Loss of feedback inhibition via D2 autoreceptors enhances acquisition of cocaine taking and reactivity to drug-paired cues. | Holroyd KB et al. | β | 2015 | β |
| Low gamma wave oscillations in the striatum of mice following morphine administration. | Reakkamnuan C et al. | β | 2015 | β |
| Neurobiological Bases of Cue- and Nicotine-induced Reinstatement of Nicotine Seeking: Implications for the Development of Smoking Cessation Medications. | Stoker AK et al. | β | 2015 | β |
| On the invariance of the Stimulant Craving Questionnaire (STCQ) across cocaine and methamphetamine users. | Northrup TF et al. | β | 2015 | β |
| Overlapping patterns of brain activation to food and cocaine cues in cocaine abusers: association to striatal D2/D3 receptors. | Tomasi D et al. | β | 2015 | β |
| Reduced frontal cortical thickness and increased caudate volume within fronto-striatal circuits in young adult smokers. | Li Y et al. | β | 2015 | β |
| Relationship between drug dreams, affect, and craving during treatment for substance dependence. | Tanguay H et al. | β | 2015 | β |
| Reward-based decision making in pathological gambling: the roles of risk and delay. | Wiehler A et al. | β | 2015 | β |
| Selective activation of the trace amine-associated receptor 1 decreases cocaine's reinforcing efficacy and prevents cocaine-induced changes in brain reward thresholds. | Pei Y et al. | β | 2015 | β |
| Sign-tracking to an appetitive cue predicts incubation of conditioned fear in rats. | Morrow JD et al. | β | 2015 | β |
| Striatal morphology is associated with tobacco cigarette craving. | Janes AC et al. | β | 2015 | β |
| The Brain on Drugs: From Reward to Addiction. | Volkow ND et al. | β | 2015 | β |
| The dopamine theory of addiction: 40 years of highs and lows. | Nutt DJ et al. | β | 2015 | β |
| The mediating effect of prefrontal asymmetry on the relationship between the COMT Val(158)Met SNP and trait consummatory positive affect. | Katz AC et al. | β | 2015 | β |
| The Nucleus Accumbens: A Comprehensive Review. | Salgado S et al. | β | 2015 | β |
| Abstinence duration modulates striatal functioning during monetary reward processing in cocaine patients. | Bustamante JC et al. | β | 2014 | β |
| Addiction science: Uncovering neurobiological complexity. | Volkow ND et al. | β | 2014 | β |
| A dual-systems perspective on addiction: contributions from neuroimaging and cognitive training. | McClure SM et al. | β | 2014 | β |
| Amphetamine sensitization alters reward processing in the human striatum and amygdala. | O'Daly OG et al. | β | 2014 | β |
| An increase in tobacco craving is associated with enhanced medial prefrontal cortex network coupling. | Janes AC et al. | β | 2014 | β |
| Blockade of D3 receptors by YQA14 inhibits cocaine's rewarding effects and relapse to drug-seeking behavior in rats. | Song R et al. | β | 2014 | β |
| Brain activation to cocaine cues and motivation/treatment status. | Prisciandaro JJ et al. | β | 2014 | β |
| Brain reward region responsivity of adolescents with and without parental substance use disorders. | Stice E et al. | β | 2014 | β |
| Cerebral gray matter volumes and low-frequency fluctuation of BOLD signals in cocaine dependence: duration of use and gender difference. | Ide JS et al. | β | 2014 | β |
| Choosing Money over Drugs: The Neural Underpinnings of Difficult Choice in Chronic Cocaine Users. | Wesley MJ et al. | β | 2014 | β |
| Chronic wheel running affects cocaine-induced c-Fos expression in brain reward areas in rats. | Zlebnik NE et al. | β | 2014 | β |
| Cocaine-associated odor cue re-exposure increases blood oxygenation level dependent signal in memory and reward regions of the maternal rat brain. | Caffrey MK et al. | β | 2014 | β |
| Cocaine dependent individuals with attenuated striatal activation during reinforcement learning are more susceptible to relapse. | Stewart JL et al. | β | 2014 | β |
| Cocaine self-administration abolishes associative neural encoding in the nucleus accumbens necessary for higher-order learning. | Saddoris MP et al. | β | 2014 | β |
| Complexity of oxytocinΧ³s effects in a chronic cocaine dependent population. | Lee MR et al. | β | 2014 | β |
| Compulsivity in anorexia nervosa: a transdiagnostic concept. | Godier LR et al. | β | 2014 | β |
| Cue-induced craving increases impulsivity via changes in striatal value signals in problem gamblers. | Miedl SF et al. | β | 2014 | β |
| Cue reactivity is associated with duration and severity of alcohol dependence: an FMRI study. | Sjoerds Z et al. | β | 2014 | β |
| Disruption of glutamate receptor-interacting protein in nucleus accumbens enhances vulnerability to cocaine relapse. | Briand LA et al. | β | 2014 | β |
| Dopamine and glutamate interaction mediates reinstatement of drug-seeking behavior by stimulation of the ventral subiculum. | Taepavarapruk P et al. | β | 2014 | β |
| Dopamine and the cognitive downside of a promised bonus. | Aarts E et al. | β | 2014 | β |
| Dopamine D3 and 5-HT1B receptor dysregulation as a result of psychostimulant intake and forced abstinence: Implications for medications development. | Neisewander JL et al. | β | 2014 | β |
| Dopamine Dβ receptor alterations in cocaine-dependent humans imaged with [ΒΉΒΉC](+)PHNO. | Matuskey D et al. | β | 2014 | β |
| Effects of inhibitory GABA-active neurosteroids on cocaine seeking and cocaine taking in rats. | Schmoutz CD et al. | β | 2014 | β |
| Endocannabinoid signaling and food addiction. | D'Addario C et al. | β | 2014 | β |
| Extended-release naltrexone modulates brain response to drug cues in abstinent heroin-dependent patients. | Langleben DD et al. | β | 2014 | β |
| Extrastriatal dopaminergic changes in Parkinson's disease patients with impulse control disorders. | Lee JY et al. | β | 2014 | β |
| Factors modulating neural reactivity to drug cues in addiction: a survey of human neuroimaging studies. | Jasinska AJ et al. | β | 2014 | β |
| Food-addiction scale measurement in 2 cohorts of middle-aged and older women. | Flint AJ et al. | β | 2014 | β |
| Functional consequences of cocaine re-exposure after discontinuation of cocaine availability. | Beveridge TJ et al. | β | 2014 | β |
| Habit formation: implications for alcoholism research. | O'Tousa D et al. | β | 2014 | β |
| Habitual responding for alcohol depends upon both AMPA and D2 receptor signaling in the dorsolateral striatum. | Corbit LH et al. | β | 2014 | β |
| Have the genetics of cannabis involvement gone to pot? | Agrawal A et al. | β | 2014 | β |
| Imaging addiction: D2 receptors and dopamine signaling in the striatum as biomarkers for impulsivity. | Trifilieff P et al. | β | 2014 | β |
| Increased impulsivity retards the transition to dorsolateral striatal dopamine control of cocaine seeking. | Murray JE et al. | β | 2014 | β |
| Investigating expectation and reward in human opioid addiction with [(11) C]raclopride PET. | Watson BJ et al. | β | 2014 | β |
| Methadone maintenance patients show a selective deficit to reverse positive outcomes in drug-related conditions compared to medication free prolonged opiate abstinence. | Levy-Gigi E et al. | β | 2014 | β |
| Microinjections of a dopamine D1 receptor antagonist into the ventral tegmental area block the expression of cocaine conditioned place preference in rats. | Galaj E et al. | β | 2014 | β |
| Neural and psychological mechanisms underlying compulsive drug seeking habits and drug memories--indications for novel treatments of addiction. | Everitt BJ | β | 2014 | β |
| Neural correlates of attentional bias for smoking cues: modulation by variance in the dopamine transporter gene. | Wetherill RR et al. | β | 2014 | β |
| Neural correlates of craving and impulsivity in abstinent former cocaine users: Towards biomarkers of relapse risk. | Bell RP et al. | β | 2014 | β |
| Neural correlates of substance abuse: reduced functional connectivity between areas underlying reward and cognitive control. | Motzkin JC et al. | β | 2014 | β |
| Nipping cue reactivity in the bud: baclofen prevents limbic activation elicited by subliminal drug cues. | Young KA et al. | β | 2014 | β |
| Olfactory aversive conditioning during sleep reduces cigarette-smoking behavior. | Arzi A et al. | β | 2014 | β |
| On the motivational properties of reward cues: Individual differences. | Robinson TE et al. | β | 2014 | β |
| Opposing neural effects of naltrexone on food reward and aversion: implications for the treatment of obesity. | Murray E et al. | β | 2014 | β |
| Pharmacological interventions to modulate attentional bias in addiction. | Luijten M et al. | β | 2014 | β |
| Post-retrieval extinction attenuates cocaine memories. | Sartor GC et al. | β | 2014 | β |
| Prelimbic cortex and ventral tegmental area modulate synaptic plasticity differentially in nucleus accumbens during cocaine-reinstated drug seeking. | Shen HW et al. | β | 2014 | β |
| Reduced responses to heroin-cue-induced craving in the dorsal striatum: effects of long-term methadone maintenance treatment. | Wang Y et al. | β | 2014 | β |
| Responding for conditioned reinforcement in C57BL/6 and CD-1 mice, and Sprague-Dawley rats: Effects of methylphenidate and amphetamine. | Browne JD et al. | β | 2014 | β |
| Similar roles of substantia nigra and ventral tegmental dopamine neurons in reward and aversion. | Ilango A et al. | β | 2014 | β |
| Stimulant-induced dopamine increases are markedly blunted in active cocaine abusers. | Volkow ND et al. | β | 2014 | β |
| Stress-induced dopamine response in subjects at clinical high risk for schizophrenia with and without concurrent cannabis use. | Mizrahi R et al. | β | 2014 | β |
| Striatum inhibition: clues for cocaine addiction therapy. | Boudjani H et al. | β | 2014 | β |
| Tales from the dark side: do neuromodulators of drug withdrawal require changes in endocannabinoid tone? | Oleson EB et al. | β | 2014 | β |
| Temporal difference error prediction signal dysregulation in cocaine dependence. | Rose EJ et al. | β | 2014 | β |
| Temporal profile of fronto-striatal-limbic activity during implicit decisions in drug dependence. | Yamamoto DJ et al. | β | 2014 | β |
| The cerebral representation of scratching-induced pleasantness. | Mochizuki H et al. | β | 2014 | β |
| The neural network underlying incentive-based learning: implications for interpreting circuit disruptions in psychiatric disorders. | Haber SN et al. | β | 2014 | β |
| The neurobiology of alcohol craving and relapse. | Seo D et al. | β | 2014 | β |
| The place of dopamine in the cortico-basal ganglia circuit. | Haber SN | β | 2014 | β |
| The role of learning-related dopamine signals in addiction vulnerability. | Huys QJ et al. | β | 2014 | β |
| Too difficult to stop: mechanisms facilitating relapse in alcohol dependence. | Garbusow M et al. | β | 2014 | β |
| Using a drug-word Stroop task to differentiate recreational from dependent drug use. | Smith DG et al. | β | 2014 | β |
| Acute cocaine induced deficits in cognitive performance in rhesus macaque monkeys treated with baclofen. | Porrino LJ et al. | β | 2013 | β |
| Addiction and corticotropin-releasing hormone type 1 receptor antagonist medications. | Contoreggi C et al. | β | 2013 | β |
| Addiction: failure of control over maladaptive incentive habits. | Belin D et al. | β | 2013 | β |
| Altered fronto-striatal and fronto-cerebellar circuits in heroin-dependent individuals: a resting-state FMRI study. | Wang Y et al. | β | 2013 | β |
| Ambivalence about smoking and cue-elicited neural activity in quitting-motivated smokers faced with an opportunity to smoke. | Wilson SJ et al. | β | 2013 | β |
| An Exploration of Responses to Drug Conditioned Stimuli during Treatment for Substance Dependence. | Goddard B et al. | β | 2013 | β |
| A Novel Perspective on Dopaminergic Processing of Human Addiction. | Badgaiyan RD | β | 2013 | β |
| A targeted review of the neurobiology and genetics of behavioural addictions: an emerging area of research. | Leeman RF et al. | β | 2013 | β |
| Beer flavor provokes striatal dopamine release in male drinkers: mediation by family history of alcoholism. | Oberlin BG et al. | β | 2013 | β |
| Blockade of dopamine D3 receptors in the nucleus accumbens and central amygdala inhibits incubation of cocaine craving in rats. | Xi ZX et al. | β | 2013 | β |
| Blue-yellow colour vision impairment and cognitive deficits in occasional and dependent stimulant users. | Hulka LM et al. | β | 2013 | β |
| Cocaine cue-induced dopamine release in amygdala and hippocampus: a high-resolution PET [ΒΉβΈF]fallypride study in cocaine dependent participants. | Fotros A et al. | β | 2013 | β |
| Cortico-subcortical activation patterns for itch and pain imagery. | Mochizuki H et al. | β | 2013 | β |
| Cue-evoked cocaine "craving": role of dopamine in the accumbens core. | Saunders BT et al. | β | 2013 | β |
| Cue-induced conditioned activity does not incubate but is mediated by the basolateral amygdala. | Diehl GW et al. | β | 2013 | β |
| Cytochrome P450 2D6 poor metabolism, curvilinearity, and response: an intriguing observation requiring integration of psychopharmacology into pharmacogenetics. | Al Hadithy AF et al. | β | 2013 | β |
| Deep brain stimulation surgery for alcohol addiction. | Voges J et al. | β | 2013 | β |
| Differential expression of Arc in the mesocorticolimbic system is involved in drug and natural rewarding behavior in rats. | Li M et al. | β | 2013 | β |
| Differential role of ventral tegmental area acetylcholine and N-methyl-D-aspartate receptors in cocaine-seeking. | Solecki W et al. | β | 2013 | β |
| Dopamine transporter availability in heroin-dependent subjects and controls: longitudinal changes during abstinence and the effects of Jitai tablets treatment. | Liu Y et al. | β | 2013 | β |
| Effects of methylphenidate on resting-state functional connectivity of the mesocorticolimbic dopamine pathways in cocaine addiction. | Konova AB et al. | β | 2013 | β |
| From the ventral to the dorsal striatum: devolving views of their roles in drug addiction. | Everitt BJ et al. | β | 2013 | β |
| Genetic influences on craving for alcohol. | Agrawal A et al. | β | 2013 | β |
| Gene x abstinence effects on drug cue reactivity in addiction: multimodal evidence. | Moeller SJ et al. | β | 2013 | β |
| Imaging impulse control disorders in Parkinson's disease and their relationship to addiction. | Ray NJ et al. | β | 2013 | β |
| Imbalanced decision hierarchy in addicts emerging from drug-hijacked dopamine spiraling circuit. | Keramati M et al. | β | 2013 | β |
| Increased turnover of dopamine in caudate nucleus of detoxified alcoholic patients. | Kumakura Y et al. | β | 2013 | β |
| Individual variation in resisting temptation: implications for addiction. | Saunders BT et al. | β | 2013 | β |
| Instant transformation of learned repulsion into motivational "wanting". | Robinson MJ et al. | β | 2013 | β |
| Interactions between the nucleus accumbens and auditory cortices predict music reward value. | Salimpoor VN et al. | β | 2013 | β |
| Lack of increased immediate early gene expression in rats reinstating cocaine-seeking behavior to discrete sensory cues. | Riedy MD et al. | β | 2013 | β |
| Mindful attention reduces neural and self-reported cue-induced craving in smokers. | Westbrook C et al. | β | 2013 | β |
| Mindfulness-based relapse prevention for substance craving. | Witkiewitz K et al. | β | 2013 | β |
| Modeling relapse situations in the human laboratory. | Sinha R | β | 2013 | β |
| Netrin-1 receptor-deficient mice show age-specific impairment in drug-induced locomotor hyperactivity but still self-administer methamphetamine. | Kim JH et al. | β | 2013 | β |
| Neural correlates of motor vigour and motor urgency during exercise. | Rauch HG et al. | β | 2013 | β |
| Neural processing of a cocaine-associated odor cue revealed by functional MRI in awake rats. | Johnson TR et al. | β | 2013 | β |
| Neuroadaptive changes associated with smoking: structural and functional neural changes in nicotine dependence. | Martin-Soelch C | β | 2013 | β |
| Pain and suicidality: insights from reward and addiction neuroscience. | Elman I et al. | β | 2013 | β |
| Presentation of smoking-associated cues does not elicit dopamine release after one-hour smoking abstinence: A [11C]-(+)-PHNO PET study. | Chiuccariello L et al. | β | 2013 | β |
| Protein kinase G regulates dopamine release, ΞFosB expression, and locomotor activity after repeated cocaine administration: involvement of dopamine D2 receptors. | Lee DK et al. | β | 2013 | β |
| Reduced neural tracking of prediction error in substance-dependent individuals. | Tanabe J et al. | β | 2013 | β |
| Reward-related brain response and craving correlates of marijuana cue exposure: a preliminary study in treatment-seeking marijuana-dependent subjects. | Goldman M et al. | β | 2013 | β |
| Robust changes in reward circuitry during reward loss in current and former cocaine users during performance of a monetary incentive delay task. | Patel KT et al. | β | 2013 | β |
| Roles of dopaminergic innervation of nucleus accumbens shell and dorsolateral caudate-putamen in cue-induced morphine seeking after prolonged abstinence and the underlying D1- and D2-like receptor mechanisms in rats. | Gao J et al. | β | 2013 | β |
| Stress differentially alters mu opioid receptor density and trafficking in parvalbumin-containing interneurons in the female and male rat hippocampus. | Milner TA et al. | β | 2013 | β |
| Striatal-insula circuits in cocaine addiction: implications for impulsivity and relapse risk. | McHugh MJ et al. | β | 2013 | β |
| Striatal ups and downs: their roles in vulnerability to addictions in humans. | Leyton M et al. | β | 2013 | β |
| Systems level neuroplasticity in drug addiction. | Feltenstein MW et al. | β | 2013 | β |
| The addictive dimensionality of obesity. | Volkow ND et al. | β | 2013 | β |
| The clinical neurobiology of drug craving. | Sinha R | β | 2013 | β |
| The contribution of brain reward circuits to the obesity epidemic. | Stice E et al. | β | 2013 | β |
| The neurobiological underpinnings of obesity and binge eating: a rationale for adopting the food addiction model. | Smith DG et al. | β | 2013 | β |
| The neurochemistry of music. | Chanda ML et al. | β | 2013 | β |
| [Tobacco use and illicit substance use disorders: what should we have to do?]. | Karila L et al. | β | 2013 | β |
| Translating positron emission tomography studies in animals to stimulant addiction: promises and pitfalls. | Caprioli D et al. | β | 2013 | β |
| A comparison of therapies for the treatment of drug cues: counterconditioning vs. extinction in male rats. | Tunstall BJ et al. | β | 2012 | β |
| Addiction circuitry in the human brain. | Volkow ND et al. | β | 2012 | β |
| Age and sex differences in impulsive action in rats: the role of dopamine and glutamate. | Burton CL et al. | β | 2012 | β |
| Are tobacco dependence and withdrawal related amongst heavy smokers? Relevance to conceptualizations of dependence. | Baker TB et al. | β | 2012 | β |
| Availability of dopamine and serotonin transporters in opioid-dependent users--a two-isotope SPECT study. | Yeh TL et al. | β | 2012 | β |
| Brain activation associated with attentional bias in smokers is modulated by a dopamine antagonist. | Luijten M et al. | β | 2012 | β |
| Changes in nucleus accumbens and neostriatal c-Fos and DARPP-32 immunoreactivity during different stages of food-reinforced instrumental training. | Segovia KN et al. | β | 2012 | β |
| Compulsive drug use and its neural substrates. | Lesscher HM et al. | β | 2012 | β |
| Craving correlates with mesolimbic responses to heroin-related cues in short-term abstinence from heroin: an event-related fMRI study. | Li Q et al. | β | 2012 | β |
| Cue-elicited craving in heroin addicts at different abstinent time: an fMRI pilot study. | Lou M et al. | β | 2012 | β |
| Cue-induced reinstatement of cocaine seeking in the rat "conflict model": effect of prolonged home-cage confinement. | Barnea-Ygael N et al. | β | 2012 | β |
| Damage in the dorsal striatum alleviates addictive behavior. | Muskens JB et al. | β | 2012 | β |
| Deepened extinction of cocaine cues. | Kearns DN et al. | β | 2012 | β |
| Differential patterns of neuronal activation in rostral versus caudal ventral tegmental area involved in behavioral sensitization induced by an escalating-dose morphine administration paradigm. | Bai Y et al. | β | 2012 | β |
| Differential roles of the dorsolateral and midlateral striatum in punished cocaine seeking. | Jonkman S et al. | β | 2012 | β |
| Distinct contributions of dopamine in the dorsolateral striatum and nucleus accumbens shell to the reinforcing properties of cocaine. | Veeneman MM et al. | β | 2012 | β |
| Dopamine and glutamate release in the dorsolateral caudate putamen following withdrawal from cocaine self-administration in rats. | Gabriele A et al. | β | 2012 | β |
| Double dissociation of the dorsomedial and dorsolateral striatal control over the acquisition and performance of cocaine seeking. | Murray JE et al. | β | 2012 | β |
| Drug-related cues exacerbate decision making and increase craving in heroin addicts at different abstinence times. | Wang GB et al. | β | 2012 | β |
| Emotional arousal and multiple memory systems in the mammalian brain. | Packard MG et al. | β | 2012 | β |
| Enhanced dorsolateral striatal activity in drug use: the role of outcome in stimulus-response associations. | Schneck N et al. | β | 2012 | β |
| Enhanced midbrain response at 6-month follow-up in cocaine addiction, association with reduced drug-related choice. | Moeller SJ et al. | β | 2012 | β |
| Enkephalin surges in dorsal neostriatum as a signal to eat. | DiFeliceantonio AG et al. | β | 2012 | β |
| Ethanol drinking-in-the-dark facilitates behavioral sensitization to ethanol in C57BL/6J, BALB/cByJ, but not in mu-opioid receptor deficient CXBK mice. | TarragΓ³n E et al. | β | 2012 | β |
| Experimental protocols for behavioral imaging: seeing animal models of drug abuse in a new light. | Aarons AR et al. | β | 2012 | β |
| Extinguished cocaine cues increase drug seeking when presented simultaneously with a non-extinguished cocaine cue. | Kearns DN et al. | β | 2012 | β |
| Food and drug reward: overlapping circuits in human obesity and addiction. | Volkow ND et al. | β | 2012 | β |
| Glycine transporter-1 inhibition preceding extinction training inhibits reacquisition of cocaine seeking. | Achat-Mendes C et al. | β | 2012 | β |
| How acute and chronic alcohol consumption affects brain networks: insights from multimodal neuroimaging. | Schulte T et al. | β | 2012 | β |
| How does stress lead to risk of alcohol relapse? | Sinha R | β | 2012 | β |
| Imaging human reward processing with positron emission tomography and functional magnetic resonance imaging. | Urban NB et al. | β | 2012 | β |
| Impulse control disorders in Parkinson's disease: background and update on prevention and management. | Leeman RF et al. | β | 2012 | β |
| Individual differences in smoking-related cue reactivity in smokers: an eye-tracking and fMRI study. | Kang OS et al. | β | 2012 | β |
| Insights to drug addiction derived from ultrastructural views of the mesocorticolimbic system. | Morales M et al. | β | 2012 | β |
| Mapping the central effects of chronic ketamine administration in an adolescent primate model by functional magnetic resonance imaging (fMRI). | Yu H et al. | β | 2012 | β |
| Mirtazapine, and mirtazapine-like compounds as possible pharmacotherapy for substance abuse disorders: evidence from the bench and the bedside. | Graves SM et al. | β | 2012 | β |
| Neural correlates of stress-induced and cue-induced drug craving: influences of sex and cocaine dependence. | Potenza MN et al. | β | 2012 | β |
| Neural substrates of smoking cue reactivity: a meta-analysis of fMRI studies. | Engelmann JM et al. | β | 2012 | β |
| Neurocircuitry for modeling drug effects. | Noori HR et al. | β | 2012 | β |
| Neuronal nicotinic acetylcholine receptors: neuroplastic changes underlying alcohol and nicotine addictions. | Feduccia AA et al. | β | 2012 | β |
| Nonhuman primate models of addiction and PET imaging: dopamine system dysregulation. | Gould RW et al. | β | 2012 | β |
| Prefrontal and limbic resting state brain network functional connectivity differs between nicotine-dependent smokers and non-smoking controls. | Janes AC et al. | β | 2012 | β |
| Quantifying individual variation in the propensity to attribute incentive salience to reward cues. | Meyer PJ et al. | β | 2012 | β |
| Rationale and consequences of reclassifying obesity as an addictive disorder: neurobiology, food environment and social policy perspectives. | Allen PJ et al. | β | 2012 | β |
| Reduced grey matter in the posterior insula as a structural vulnerability or diathesis to addiction. | Gardini S et al. | β | 2012 | β |
| Reduction in neural activation to high-calorie food cues in obese endometrial cancer survivors after a behavioral lifestyle intervention: a pilot study. | Nock NL et al. | β | 2012 | β |
| Reliability of striatal [ΒΉΒΉC]raclopride binding in smokers wearing transdermal nicotine patches. | Yoder KK et al. | β | 2012 | β |
| Responses to novelty and vulnerability to cocaine addiction: contribution of a multi-symptomatic animal model. | Belin D et al. | β | 2012 | β |
| Reversal learning as a measure of impulsive and compulsive behavior in addictions. | Izquierdo A et al. | β | 2012 | β |
| Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings. | Dichter GS et al. | β | 2012 | β |
| Reward-related dorsal striatal activity differences between former and current cocaine dependent individuals during an interactive competitive game. | Hyatt CJ et al. | β | 2012 | β |
| Similarities and differences between pathological gambling and substance use disorders: a focus on impulsivity and compulsivity. | Leeman RF et al. | β | 2012 | β |
| Specific knockdown of the D2 long dopamine receptor variant. | Naughton BJ et al. | β | 2012 | β |
| Structural and behavioral correlates of abnormal encoding of money value in the sensorimotor striatum in cocaine addiction. | Konova AB et al. | β | 2012 | β |
| The atypical antidepressant mirtazapine attenuates expression of morphine-induced place preference and motor sensitization. | Graves SM et al. | β | 2012 | β |
| The detrimental effects of emotional process dysregulation on decision-making in substance dependence. | Murphy A et al. | β | 2012 | β |
| Trait impulsivity and prefrontal gray matter reductions in cocaine dependent individuals. | Moreno-LΓ³pez L et al. | β | 2012 | β |
| Transgenic expression of ZBP1 in neurons suppresses cocaine-associated conditioning. | Lapidus KA et al. | β | 2012 | β |
| Treatment-like steady-state methadone in rats interferes with incubation of cocaine sensitization and associated alterations in gene expression. | Leri F et al. | β | 2012 | β |
| Aberrant learning and memory in addiction. | Torregrossa MM et al. | β | 2011 | β |
| Addiction and brain reward and antireward pathways. | Gardner EL | β | 2011 | β |
| Addiction: beyond dopamine reward circuitry. | Volkow ND et al. | β | 2011 | β |
| Advances in animal models of drug addiction. | Heidbreder C | β | 2011 | β |
| A food predictive cue must be attributed with incentive salience for it to induce c-fos mRNA expression in cortico-striatal-thalamic brain regions. | Flagel SB et al. | β | 2011 | β |
| Basal Ganglia disorders associated with imbalances in the striatal striosome and matrix compartments. | Crittenden JR et al. | β | 2011 | β |
| Buprenorphine modulates methamphetamine-induced dopamine dynamics in the rat caudate nucleus. | Pereira FC et al. | β | 2011 | β |
| Chronic alcohol neuroadaptation and stress contribute to susceptibility for alcohol craving and relapse. | Breese GR et al. | β | 2011 | β |
| Chronic morphine alters the presynaptic protein profile: identification of novel molecular targets using proteomics and network analysis. | Abul-Husn NS et al. | β | 2011 | β |
| Cocaine cues drive opposing context-dependent shifts in reward processing and emotional state. | Wheeler RA et al. | β | 2011 | β |
| Cortical and sub-cortical effects in primate models of cocaine use: implications for addiction and the increased risk of psychiatric illness. | Bradberry CW | β | 2011 | β |
| [Cue exposure treatment and coping skills training as adjuvant therapies in the management of craving in a crack cocaine addict]. | Araujo RB et al. | β | 2011 | β |
| Cue-induced striatal dopamine release in Parkinson's disease-associated impulsive-compulsive behaviours. | O'Sullivan SS et al. | β | 2011 | β |
| Differences in "bottom-up" and "top-down" neural activity in current and former cigarette smokers: Evidence for neural substrates which may promote nicotine abstinence through increased cognitive control. | Nestor L et al. | β | 2011 | β |
| Differential effects of stress on [ΒΉΒΉC]raclopride and [ΒΉΒΉC]MNPA binding to striatal Dβ/Dβ dopamine receptors: a PET study in conscious monkeys. | Tsukada H et al. | β | 2011 | β |
| Different physiological properties of spontaneous excitatory postsynaptic currents in nucleus accumbens shell neurons between adult and juvenile rats. | Liu XD et al. | β | 2011 | β |
| Disruptive effect of amphetamines on Pavlovian to instrumental transfer. | Hall DA et al. | β | 2011 | β |
| Distinct resting-state brain activities in heroin-dependent individuals. | Zhang Y et al. | β | 2011 | β |
| Do brain responses to emotional images and cigarette cues differ? An fMRI study in smokers. | Versace F et al. | β | 2011 | β |
| Dopamine agonists for the treatment of cocaine dependence. | Amato L et al. | β | 2011 | β |
| Dorsal striatum mediation of cocaine-seeking after withdrawal from short or long daily access cocaine self-administration in rats. | Pacchioni AM et al. | β | 2011 | β |
| DSM-IV to DSM-5: the impact of proposed revisions on diagnosis of alcohol use disorders. | Agrawal A et al. | β | 2011 | β |
| Effects of cocaine rewards on neural representations of cognitive demand in nonhuman primates. | Hampson RE et al. | β | 2011 | β |
| Ethanol-induced modulation of synaptic output from the dorsolateral striatum in rat is regulated by cholinergic interneurons. | Adermark L et al. | β | 2011 | β |
| Evidence for learned skill during cocaine self-administration in rats. | Root DH et al. | β | 2011 | β |
| Expanding applications of deep brain stimulation: a potential therapeutic role in obesity and addiction management. | Halpern CH et al. | β | 2011 | β |
| Impulse control disorders in Parkinson's disease: clinical characteristics and implications. | Leeman RF et al. | β | 2011 | β |
| Impulse control disorders in Parkinson's disease: recent advances. | Voon V et al. | β | 2011 | β |
| Impulsivity and Parkinson's disease: more than just disinhibition. | Antonelli F et al. | β | 2011 | β |
| Lesions and reversible inactivation of the dorsolateral caudate-putamen impair cocaine-primed reinstatement to cocaine-seeking in rats. | Gabriele A et al. | β | 2011 | β |
| Mirtazapine alters cue-associated methamphetamine seeking in rats. | Graves SM et al. | β | 2011 | β |
| Molecular diffusion model of neurotransmitter homeostasis around synapses supporting gradients. | Mohan A et al. | β | 2011 | β |
| Molecular imaging in neuroscience research with small-animal PET in rodents. | Xi W et al. | β | 2011 | β |
| Motivated attention to cocaine and emotional cues in abstinent and current cocaine users--an ERP study. | Dunning JP et al. | β | 2011 | β |
| Music and methamphetamine: conditioned cue-induced increases in locomotor activity and dopamine release in rats. | Polston JE et al. | β | 2011 | β |
| Music-induced context preference following cocaine conditioning in rats. | Polston JE et al. | β | 2011 | β |
| Neural correlates of food addiction. | Gearhardt AN et al. | β | 2011 | β |
| New findings on biological factors predicting addiction relapse vulnerability. | Sinha R | β | 2011 | β |
| Reduced metabolism in brain "control networks" following cocaine-cues exposure in female cocaine abusers. | Volkow ND et al. | β | 2011 | β |
| Reduced striatal volume in cocaine-dependent patients. | BarrΓ³s-Loscertales A et al. | β | 2011 | β |
| Reward improves cancellation and restraint inhibition across childhood and adolescence. | Sinopoli KJ et al. | β | 2011 | β |
| Role of netrin-1 in the organization and function of the mesocorticolimbic dopamine system. | Flores C | β | 2011 | β |
| Selective norepinephrine reuptake inhibition by atomoxetine prevents cue-induced heroin and cocaine seeking. | Economidou D et al. | β | 2011 | β |
| Sex differences in neural responses to stress and alcohol context cues. | Seo D et al. | β | 2011 | β |
| Stability of fMRI striatal response to alcohol cues: a hierarchical linear modeling approach. | Schacht JP et al. | β | 2011 | β |
| Suppression of activity-regulated cytoskeleton-associated gene expression in the dorsal striatum attenuates extinction of cocaine-seeking. | Hearing MC et al. | β | 2011 | β |
| Test-retest variability of [ΒΉΒΉC]raclopride-binding potential in nontreatment-seeking alcoholics. | Yoder KK et al. | β | 2011 | β |
| The role of setting in the oral self-administration of alcohol in the rat. | Testa A et al. | β | 2011 | β |
| Translational research in addiction: toward a framework for the development of novel therapeutics. | Paterson NE | β | 2011 | β |
| Treatment of addiction and anxiety using extinction approaches: neural mechanisms and their treatment implications. | Kaplan GB et al. | β | 2011 | β |
| Acute effects of sublingual buprenorphine on brain responses to heroin-related cues in early-abstinent heroin addicts: an uncontrolled trial. | Mei W et al. | β | 2010 | β |
| Addiction and cognition. | Gould TJ | β | 2010 | β |
| Addiction: decreased reward sensitivity and increased expectation sensitivity conspire to overwhelm the brain's control circuit. | Volkow ND et al. | β | 2010 | β |
| AMPA receptor synaptic plasticity induced by psychostimulants: the past, present, and therapeutic future. | Bowers MS et al. | β | 2010 | β |
| Amygdala mechanisms of Pavlovian psychostimulant conditioning and relapse. | Buffalari DM et al. | β | 2010 | β |
| Associations with substance abuse treatment completion among drug court participants. | Brown R | β | 2010 | β |
| Cognitive control of drug craving inhibits brain reward regions in cocaine abusers. | Volkow ND et al. | β | 2010 | β |
| Comorbidity of ADHD and Substance Use Disorder (SUD): a neuroimaging perspective. | Frodl T | β | 2010 | β |
| Cortical activation during cocaine use and extinction in rhesus monkeys. | Howell LL et al. | β | 2010 | β |
| Disrupting the memory of places induced by drugs of abuse weakens motivational withdrawal in a context-dependent manner. | Taubenfeld SM et al. | β | 2010 | β |
| Dopamine, reward, and frontostriatal circuitry in impulse control disorders in Parkinson's disease: insights from functional imaging. | Ray N et al. | β | 2010 | β |
| Drug seeking in response to a priming injection of MDMA in rats: relationship to initial sensitivity to self-administered MDMA and dorsal striatal dopamine. | Colussi-Mas J et al. | β | 2010 | β |
| Electrophysiological correlates of abused drugs: relation to natural rewards. | Deadwyler SA | β | 2010 | β |
| Environmental living conditions introduced during forced abstinence alter cocaine-seeking behavior and Fos protein expression. | Thiel KJ et al. | β | 2010 | β |
| Hippocampal and striatal gray matter volume are associated with a smoking cessation treatment outcome: results of an exploratory voxel-based morphometric analysis. | Froeliger B et al. | β | 2010 | β |
| Imaging cognitive deficits in drug abuse. | Lundqvist T | β | 2010 | β |
| Imaging neurotransmitter release by drugs of abuse. | Martinez D et al. | β | 2010 | β |
| Impaired insight in cocaine addiction: laboratory evidence and effects on cocaine-seeking behaviour. | Moeller SJ et al. | β | 2010 | β |
| Individual differences in nucleus accumbens dopamine receptors predict development of addiction-like behavior: a computational approach. | Piray P et al. | β | 2010 | β |
| Influence of compulsivity of drug abuse on dopaminergic modulation of attentional bias in stimulant dependence. | Ersche KD et al. | β | 2010 | β |
| Initial, habitual and compulsive alcohol use is characterized by a shift of cue processing from ventral to dorsal striatum. | VollstΓ€dt-Klein S et al. | β | 2010 | β |
| Insights into pathophysiology of punding reveal possible treatment strategies. | Fasano A et al. | β | 2010 | β |
| Kicking the habit: the neural basis of ingrained behaviors in cocaine addiction. | Pierce RC et al. | β | 2010 | β |
| Liking and wanting of drug and non-drug rewards in active cocaine users: the STRAP-R questionnaire. | Goldstein RZ et al. | β | 2010 | β |
| Measuring addiction propensity and severity: the need for a new instrument. | Conway KP et al. | β | 2010 | β |
| Methylphenidate attenuates limbic brain inhibition after cocaine-cues exposure in cocaine abusers. | Volkow ND et al. | β | 2010 | β |
| Neurocircuitry of addiction. | Koob GF et al. | β | 2010 | β |
| Neuropharmacology of addiction and how it informs treatment. | Lingford-Hughes A et al. | β | 2010 | β |
| Orbitofrontal and insular cortex: neural responses to cocaine-associated cues and cocaine self-administration. | Guillem K et al. | β | 2010 | β |
| Overeating Behavior and Striatal Dopamine with 6-[F]-Fluoro-L-m-Tyrosine PET. | Wilcox CE et al. | β | 2010 | β |
| Prefrontal-striatal pathway underlies cognitive regulation of craving. | Kober H et al. | β | 2010 | β |
| Reactivity to laboratory stress provocation predicts relapse to cocaine. | Back SE et al. | β | 2010 | β |
| Reversal-specific learning impairments after a binge regimen of methamphetamine in rats: possible involvement of striatal dopamine. | Izquierdo A et al. | β | 2010 | β |
| Reversible inactivation of the basolateral amygdala, but not the dorsolateral caudate putamen, attenuates consolidation of cocaine-cue associative learning in a reinstatement model of drug-seeking. | Gabriele A et al. | β | 2010 | β |
| Reward, addiction, and emotion regulation systems associated with rejection in love. | Fisher HE et al. | β | 2010 | β |
| Search for genetic markers and functional variants involved in the development of opiate and cocaine addiction and treatment. | Yuferov V et al. | β | 2010 | β |
| Shift from goal-directed to habitual cocaine seeking after prolonged experience in rats. | Zapata A et al. | β | 2010 | β |
| Striatal dopamine D2 receptor availability predicts the thalamic and medial prefrontal responses to reward in cocaine abusers three years later. | Asensio S et al. | β | 2010 | β |
| The effects of home-cage access to a sweet solution on the discriminative stimulus effects of cocaine. | Kohut SJ et al. | β | 2010 | β |
| The emergence of gonadal hormone influences on dopaminergic function during puberty. | Kuhn C et al. | β | 2010 | β |
| The nicotinic acetylcholine receptor partial agonist varenicline and the treatment of drug dependence: a review. | Crunelle CL et al. | β | 2010 | β |
| The reward circuit: linking primate anatomy and human imaging. | Haber SN et al. | β | 2010 | β |
| Why gamblers fail to win: a review of cognitive and neuroimaging findings in pathological gambling. | van Holst RJ et al. | β | 2010 | β |
| 24-h smoking abstinence potentiates fMRI-BOLD activation to smoking cues in cerebral cortex and dorsal striatum. | McClernon FJ et al. | β | 2009 | β |
| Acute systemic blockade of D2 receptors does not accelerate the extinction of cocaine-associated place preference. | Yim AJ et al. | β | 2009 | β |
| A functional haplotype implicated in vulnerability to develop cocaine dependence is associated with reduced PDYN expression in human brain. | Yuferov V et al. | β | 2009 | β |
| Animal studies trigger new insights on the use of methadone maintenance. | Cummins E et al. | β | 2009 | β |
| Anxiety, cognition, and habit: a multiple memory systems perspective. | Packard MG | β | 2009 | β |
| Attenuation of cocaine-seeking by progesterone treatment in female rats. | Feltenstein MW et al. | β | 2009 | β |
| Brain activities associated with gaming urge of online gaming addiction. | Ko CH et al. | β | 2009 | β |
| Brain fMRI reactivity to smoking-related images before and during extended smoking abstinence. | Janes AC et al. | β | 2009 | β |
| Brain regions related to tool use and action knowledge reflect nicotine dependence. | Yalachkov Y et al. | β | 2009 | β |
| Cabergoline decreases alcohol drinking and seeking behaviors via glial cell line-derived neurotrophic factor. | Carnicella S et al. | β | 2009 | β |
| Cocaine craving and use during daily life. | Preston KL et al. | β | 2009 | β |
| Cocaine self-administration alters the relative effectiveness of multiple memory systems during extinction. | Gabriele A et al. | β | 2009 | β |
| Conditioned cues and the expression of stimulant sensitization in animals and humans. | Vezina P et al. | β | 2009 | β |
| Crime and Nourishment: Cause for a rethink? | Ramsbotham LD et al. | β | 2009 | β |
| Cue-induced dopamine release predicts cocaine preference: positron emission tomography studies in freely moving rodents. | Schiffer WK et al. | β | 2009 | β |
| DAT genotype modulates brain and behavioral responses elicited by cigarette cues. | Franklin TR et al. | β | 2009 | β |
| Decreased drug-cue-induced attentional bias in individuals with treated and untreated drug dependence. | Gardini S et al. | β | 2009 | β |
| Dissecting components of reward: 'liking', 'wanting', and learning. | Berridge KC et al. | β | 2009 | β |
| Dopaminergic activity in depressed smokers: a positron emission tomography study. | Busto UE et al. | β | 2009 | β |
| Dopaminergic response to drug words in cocaine addiction. | Goldstein RZ et al. | β | 2009 | β |
| Effect of the TaqIA polymorphism on ethanol response in the brain. | London ED et al. | β | 2009 | β |
| Emphasizing interpersonal factors: an extension of the Witkiewitz and Marlatt relapse model. | Hunter-Reel D et al. | β | 2009 | β |
| Enhanced choice for viewing cocaine pictures in cocaine addiction. | Moeller SJ et al. | β | 2009 | β |
| Ethics in substance use disorder treatment. | Geppert CM et al. | β | 2009 | β |
| Functional neuroimaging of reward circuitry responsivity to monetary gains and losses in posttraumatic stress disorder. | Elman I et al. | β | 2009 | β |
| How long does craving predict use of methamphetamine? Assessment of use one to seven weeks after the assessment of craving: Craving and ongoing methamphetamine use. | Galloway GP et al. | β | 2009 | β |
| Identifying the neural circuitry of alcohol craving and relapse vulnerability. | Heinz A et al. | β | 2009 | β |
| Imaging dopamine's role in drug abuse and addiction. | Volkow ND et al. | β | 2009 | β |
| Imaging the Conditioned Behavioral Effects of Methamphetamine in Rodents. | Carrion J et al. | β | 2009 | β |
| Increased striatal dopamine release in Parkinsonian patients with pathological gambling: a [11C] raclopride PET study. | Steeves TD et al. | β | 2009 | β |
| Loss of cocaine locomotor response in Pitx3-deficient mice lacking a nigrostriatal pathway. | Beeler JA et al. | β | 2009 | β |
| Loss of functional specificity in the dorsal striatum of chronic cocaine users. | Hanlon CA et al. | β | 2009 | β |
| Maturation of coordinated immediate early gene expression by cocaine during adolescence. | Caster JM et al. | β | 2009 | β |
| Modeling stress and drug craving in the laboratory: implications for addiction treatment development. | Sinha R | β | 2009 | β |
| Modelling human drug abuse and addiction with dedicated small animal positron emission tomography. | Dalley JW et al. | β | 2009 | β |
| Modulation of behavior by expected reward magnitude depends on dopamine in the dorsomedial striatum. | Calaminus C et al. | β | 2009 | β |
| Neural hyporesponsiveness and hyperresponsiveness during immediate and delayed reward processing in adult attention-deficit/hyperactivity disorder. | Plichta MM et al. | β | 2009 | β |
| Neural substrates of cognitive inflexibility after chronic cocaine exposure. | Stalnaker TA et al. | β | 2009 | β |
| Neuroplasticity in addictive disorders. | O'Brien CP | β | 2009 | β |
| Parallel and interactive learning processes within the basal ganglia: relevance for the understanding of addiction. | Belin D et al. | β | 2009 | β |
| Penn/VA center for studies of addiction. | O'Brien CP et al. | β | 2009 | β |
| Reward networks in the brain as captured by connectivity measures. | Camara E et al. | β | 2009 | β |
| Role of dopamine D(1)-family receptors in dorsolateral striatum in context-induced reinstatement of heroin seeking in rats. | Bossert JM et al. | β | 2009 | β |
| Steady-state methadone blocks cocaine seeking and cocaine-induced gene expression alterations in the rat brain. | Leri F et al. | β | 2009 | β |
| Targeting extinction and reconsolidation mechanisms to combat the impact of drug cues on addiction. | Taylor JR et al. | β | 2009 | β |
| The dopaminergic basis of human behaviors: A review of molecular imaging studies. | Egerton A et al. | β | 2009 | β |
| The encoding of cocaine vs. natural rewards in the striatum of nonhuman primates: categories with different activations. | Opris I et al. | β | 2009 | β |
| The GABA B agonist baclofen reduces cigarette consumption in a preliminary double-blind placebo-controlled smoking reduction study. | Franklin TR et al. | β | 2009 | β |
| The genetic basis of individual differences in reward processing and the link to addictive behavior and social cognition. | Yacubian J et al. | β | 2009 | β |
| The major symptom dimensions of obsessive-compulsive disorder are mediated by partially distinct neural systems. | van den Heuvel OA et al. | β | 2009 | β |
| The neurobiology of addictive disorders. | Ross S et al. | β | 2009 | β |
| Trafficking of dopamine transporters in psychostimulant actions. | Zahniser NR et al. | β | 2009 | β |
| Treating drug abuse and addiction in the criminal justice system: improving public health and safety. | Chandler RK et al. | β | 2009 | β |
| Ventral striatal activation during reward anticipation correlates with impulsivity in alcoholics. | Beck A et al. | β | 2009 | β |
| When what you see isn't what you get: alcohol cues, alcohol administration, prediction error, and human striatal dopamine. | Yoder KK et al. | β | 2009 | β |
| Addiction: the clinical interface. | Nutt D et al. | β | 2008 | β |
| Affective neuroscience of pleasure: reward in humans and animals. | Berridge KC et al. | β | 2008 | β |
| A unified framework for addiction: vulnerabilities in the decision process. | Redish AD et al. | β | 2008 | β |
| Chronic stress, drug use, and vulnerability to addiction. | Sinha R | β | 2008 | β |
| Cocaine abuse and sensitization of striatal dopamine transmission: a critical review of the preclinical and clinical imaging literature. | Narendran R et al. | β | 2008 | β |
| Cocaine seeking habits depend upon dopamine-dependent serial connectivity linking the ventral with the dorsal striatum. | Belin D et al. | β | 2008 | β |
| Comparison of acute and chronic neurochemical effects of cocaine and cocaine cues in rhesus monkeys and rodents: focus on striatal and cortical dopamine systems. | Bradberry CW | β | 2008 | β |
| Differential effects of nucleus accumbens core, shell, or dorsal striatal inactivations on the persistence, reacquisition, or reinstatement of responding for a drug-paired conditioned reinforcer. | Di Ciano P et al. | β | 2008 | β |
| Dopamine increases in striatum do not elicit craving in cocaine abusers unless they are coupled with cocaine cues. | Volkow ND et al. | β | 2008 | β |
| Drug addiction and the memory systems of the brain. | Robbins TW et al. | β | 2008 | β |
| Drug addiction as a pathology of staged neuroplasticity. | Kalivas PW et al. | β | 2008 | β |
| Ethanol regulation of D(1) dopamine receptor signaling is mediated by protein kinase C in an isozyme-specific manner. | Rex EB et al. | β | 2008 | β |
| Evidence for sugar addiction: behavioral and neurochemical effects of intermittent, excessive sugar intake. | Avena NM et al. | β | 2008 | β |
| First human evidence of d-amphetamine induced displacement of a D2/3 agonist radioligand: A [11C]-(+)-PHNO positron emission tomography study. | Willeit M et al. | β | 2008 | β |
| Habits, rituals, and the evaluative brain. | Graybiel AM | β | 2008 | β |
| Hippocampal regulation of contextual cue-induced reinstatement of cocaine-seeking behavior. | Atkins AL et al. | β | 2008 | β |
| Hypothesis-driven medication discovery for the treatment of psychostimulant addiction. | Xi ZX et al. | β | 2008 | β |
| Imaging dopamine release with Positron Emission Tomography (PET) and (11)C-raclopride in freely moving animals. | Patel VD et al. | β | 2008 | β |
| Impulsivity, compulsivity, and habit: the role of orbitofrontal cortex revisited. | Torregrossa MM et al. | β | 2008 | β |
| Individual differences in cocaine-induced locomotor activity in male Sprague-Dawley rats and their acquisition of and motivation to self-administer cocaine. | Mandt BH et al. | β | 2008 | β |
| Individual differences in nicotine dependence, withdrawal symptoms, and sex predict transient fMRI-BOLD responses to smoking cues. | McClernon FJ et al. | β | 2008 | β |
| Inhibitory control and emotional stress regulation: neuroimaging evidence for frontal-limbic dysfunction in psycho-stimulant addiction. | Li CS et al. | β | 2008 | β |
| [Neuroimaging and cocaine: mapping dependence?]. | Lambert G et al. | β | 2008 | β |
| New treatments for cocaine dependence: a focused review. | Karila L et al. | β | 2008 | β |
| Overlapping neuronal circuits in addiction and obesity: evidence of systems pathology. | Volkow ND et al. | β | 2008 | β |
| Parallel and integrative processing through the Basal Ganglia reward circuit: lessons from addiction. | Haber S | β | 2008 | β |
| Region-specific involvement of AMPA/Kainate receptors in Fos protein expression induced by cocaine-conditioned cues. | Zavala AR et al. | β | 2008 | β |
| Relapse to cocaine-seeking increases activity-regulated gene expression differentially in the striatum and cerebral cortex of rats following short or long periods of abstinence. | Hearing MC et al. | β | 2008 | β |
| Review. Neural mechanisms underlying the vulnerability to develop compulsive drug-seeking habits and addiction. | Everitt BJ et al. | β | 2008 | β |
| Role of Serotonin and Dopamine System Interactions in the Neurobiology of Impulsive Aggression and its Comorbidity with other Clinical Disorders. | Seo D et al. | β | 2008 | β |
| Serotonergic mechanisms in addiction-related memories. | Nic Dhonnchadha BA et al. | β | 2008 | β |
| SPECT imaging of D2 dopamine receptors and endogenous dopamine release in mice. | Jongen C et al. | β | 2008 | β |
| Striatal dopamine D2 receptor binding and dopamine release during cue-elicited craving in recently abstinent opiate-dependent males. | Zijlstra F et al. | β | 2008 | β |
| Striatal dopamine transmission in healthy humans during a passive monetary reward task. | Hakyemez HS et al. | β | 2008 | β |
| The neurocircuitry of addiction: an overview. | Feltenstein MW et al. | β | 2008 | β |
| The orbital cortex in rats topographically projects to central parts of the caudate-putamen complex. | Schilman EA et al. | β | 2008 | β |
| Widespread reward-system activation in obese women in response to pictures of high-calorie foods. | Stoeckel LE et al. | β | 2008 | β |
| Accumbal FosB/DeltaFosB immunoreactivity and conditioned place preference in alcohol-preferring AA rats and alcohol-avoiding ANA rats treated repeatedly with cocaine. | Marttila K et al. | β | 2007 | β |
| A D2 antagonist enhances the rewarding and priming effects of a gambling episode in pathological gamblers. | Zack M et al. | β | 2007 | β |
| Appetitive conditioning: neural bases and implications for psychopathology. | Martin-Soelch C et al. | β | 2007 | β |
| A role for mesencephalic dopamine in activation: commentary on Berridge (2006). | Robbins TW et al. | β | 2007 | β |
| Chronic cocaine sensitizes striatal GABAergic synapses to the stimulation of cannabinoid CB1 receptors. | Centonze D et al. | β | 2007 | β |
| Cocaine sensitization and dopamine mediation of cue effects in rodents, monkeys, and humans: areas of agreement, disagreement, and implications for addiction. | Bradberry CW | β | 2007 | β |
| Conditioned and sensitized responses to stimulant drugs in humans. | Leyton M | β | 2007 | β |
| Conditioned dopamine release in humans: a positron emission tomography [11C]raclopride study with amphetamine. | Boileau I et al. | β | 2007 | β |
| Cortico-limbic circuitry for conditioned nicotine-seeking behavior in rats involves endocannabinoid signaling. | Kodas E et al. | β | 2007 | β |
| Differential activation of the dorsal striatum by high-calorie visual food stimuli in obese individuals. | Rothemund Y et al. | β | 2007 | β |
| Drug addiction: pathways to the disease and pathophysiological perspectives. | Le Moal M et al. | β | 2007 | β |
| Effects of GABA(B) receptor agents on cocaine priming, discrete contextual cue and food induced relapses. | Filip M et al. | β | 2007 | β |
| Effects of perceived cocaine availability on subjective and objective responses to the drug. | Yamamoto RT et al. | β | 2007 | β |
| Ethanol induces long-term facilitation of NR2B-NMDA receptor activity in the dorsal striatum: implications for alcohol drinking behavior. | Wang J et al. | β | 2007 | β |
| Habit formation and the loss of control of an internal clock: inverse relationship between the level of baseline training and the clock-speed enhancing effects of methamphetamine. | Cheng RK et al. | β | 2007 | β |
| Imaging obesity: fMRI, food reward, and feeding. | Grill HJ et al. | β | 2007 | β |
| Imaging the neurochemistry of alcohol and substance abuse. | Martinez D et al. | β | 2007 | β |
| Inactivation of the lateral but not medial dorsal striatum eliminates the excitatory impact of Pavlovian stimuli on instrumental responding. | Corbit LH et al. | β | 2007 | β |
| Maximizing resilience through diverse levels of inquiry: Prevailing paradigms, possibilities, and priorities for the future. | Luthar SS et al. | β | 2007 | β |
| Methamphetamine-induced structural plasticity in the dorsal striatum. | Jedynak JP et al. | β | 2007 | β |
| Modeling the role of environment in addiction. | Caprioli D et al. | β | 2007 | β |
| Morphine effects on striatal transcriptome in mice. | Korostynski M et al. | β | 2007 | β |
| NMDA receptor blockade in the basolateral amygdala disrupts consolidation of stimulus-reward memory and extinction learning during reinstatement of cocaine-seeking in an animal model of relapse. | Feltenstein MW et al. | β | 2007 | β |
| Pharmacological actions of NGB 2904, a selective dopamine D3 receptor antagonist, in animal models of drug addiction. | Xi ZX et al. | β | 2007 | β |
| Regional brain activity correlates of nicotine dependence. | Rose JE et al. | β | 2007 | β |
| Simplifications in analyzing positron emission tomography data: effects on outcome measures. | Logan J et al. | β | 2007 | β |
| Structural and metabolic brain changes in the striatum associated with methamphetamine abuse. | Chang L et al. | β | 2007 | β |
| The debate over dopamine's role in reward: the case for incentive salience. | Berridge KC | β | 2007 | β |
| The nucleus accumbens and Pavlovian reward learning. | Day JJ et al. | β | 2007 | β |
| The role of dorsal vs ventral striatal pathways in cocaine-seeking behavior after prolonged abstinence in rats. | See RE et al. | β | 2007 | β |
| The role of stress in addiction relapse. | Sinha R | β | 2007 | β |
| Understanding the placebo effect: contributions from neuroimaging. | Lidstone SC et al. | β | 2007 | β |
| Comparing nucleus accumbens and dorsal striatal dopamine responses to self-administered cocaine in naΓ―ve rats. | D'Souza MS et al. | β | 2006 | β |
| Drug addiction: the neurobiology of disrupted self-control. | Baler RD et al. | β | 2006 | β |
| Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving. | Wong DF et al. | β | 2006 | β |