Cigarette smoking and mental illness: a study of nicotine withdrawal.
- Authors
- Smith, Philip H; Homish, Gregory G; Giovino, Gary A; Kozlowski, Lynn T
- Year
- 2014
- Journal
- American journal of public health
- PMID
- 24328637
- DOI
- 10.2105/AJPH.2013.301502
- PMCID
- PMC3935702
OBJECTIVES: We compared prevalence, severity, and specific symptom profiles for nicotine withdrawal across categories of mental illness. We also examined the influence of nicotine withdrawal on efforts to quit smoking among those with mental illness. METHODS: We analyzed data from 2 sources: wave 1 of the National Epidemiologic Survey on Alcohol and Related Conditions, limiting the sample to current smokers (2001-2002; nβ=β9913); and a 2-wave cohort telephone survey of a national sample of adult smokers (2004-2006; nβ=β751). RESULTS: Mental illness was associated with a substantially greater likelihood of nicotine withdrawal syndrome; approximately 44% of nicotine withdrawal syndrome diagnoses were attributable to mental illness. Symptom profiles were highly comparable between mental illness categories, although anxiety-related symptoms were better markers of withdrawal for those with an internalizing disorder. Smokers with mental illness were motivated to quit but were less likely to be successful in their quit attempts, and both dependence and withdrawal independently accounted for this lower likelihood of success. CONCLUSIONS: Nicotine withdrawal may be a particularly important target for intervention among those with mental illness who smoke cigarettes.
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In this knowledge base
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|---|---|---|
| A protocadherin gene cluster regulatory variant is associated with nicotine withdrawal and the urge to smoke. | 2017 | 27067016 |
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