Diagnosis of twin zygosity by mailed questionnaire.
- Authors
- Sarna, S; Kaprio, J; Sistonen, P; Koskenvuo, M
- Year
- 1978
- Journal
- Human heredity
- PMID
- 566252
- DOI
- 10.1159/000152964
A deterministic questionnaire method for zygosity determination is developed for use in epidemiological studies of adult twins. It is based on the answers of both members of a twin pair to two questions on similarity and confusion in childhood. The algorithm of the method is used to determine the zygosity status of a twin pair at two different levels of certainty. The validity of the method is tested by making blood marker determinations of 11 polymorphic marker systems fro a random sample of 104 twin pairs. The agreement between questionnaire and blood marker diagnosis was 100%, but the stricter level of certainty left 8.7% in the nonclassified group. The genetical representativeness of the sample is tested by the allele distribution of the markers as compared to the Finnish population data as well as by the distribution of the number of intra-pair differences in blood markers.
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| Stress of daily activities and risk of breast cancer: a prospective cohort study in Finland. | Lillberg K et al. | β | 2001 | β |
| Widespread pain among 11-year-old Finnish twin pairs. | Mikkelsson M et al. | β | 2001 | β |
| Cross-cultural adaptation and preliminary validation of a zygosity determination questionnaire for twins in Sri Lanka. | Sumathipala A et al. | β | 2000 | β |
| Disc degeneration and bone density in monozygotic twins discordant for insulin-dependent diabetes mellitus. | Videman T et al. | β | 2000 | β |
| Environmental and heritable factors in the causation of cancer--analyses of cohorts of twins from Sweden, Denmark, and Finland. | Lichtenstein P et al. | β | 2000 | β |
| Evidence of a substantial genetic basis for risk of adult periodontitis. | Michalowicz BS et al. | β | 2000 | β |
| Familial association between allergic disorders and depression in adult Finnish twins. | Wamboldt MZ et al. | β | 2000 | β |
| Genetic and environmental contributions to the association between body height and educational attainment: a study of adult Finnish twins. | Silventoinen K et al. | β | 2000 | β |
| Genome-wide scan of obesity in Finnish sibpairs reveals linkage to chromosome Xq24. | Ohman M et al. | β | 2000 | β |
| Heritability and risk factors of uterine fibroids--the Finnish Twin Cohort study. | Luoto R et al. | β | 2000 | β |
| Infant zygosity can be assigned by parental report questionnaire data. | Price TS et al. | β | 2000 | β |
| Low birthweight and metabolic abnormalities in twins with increased susceptibility to Type 2 diabetes mellitus. | Bo S et al. | β | 2000 | β |
| Physical activity and other risk factors in male twin-pairs discordant for coronary heart disease. | Kaprio J et al. | β | 2000 | β |
| Relative effect of genetic and environmental factors on body height: differences across birth cohorts among Finnish men and women. | Silventoinen K et al. | β | 2000 | β |
| Serum soluble tumor necrosis factor-alpha receptor 2 is elevated in obesity but is not related to insulin sensitivity: a study in identical twins discordant for obesity. | RΓΆnnemaa T et al. | β | 2000 | β |
| A twin study of individual differences in perceptual asymmetry. | Valera EM et al. | β | 1999 | β |
| Clinical characteristics of migraine in a population-based twin sample: similarities and differences between migraine with and without aura. | Kallela M et al. | β | 1999 | β |
| Comparative corneal topography and refractive variables in monozygotic and dizygotic twins. | Valluri S et al. | β | 1999 | β |
| Future hospital care in a population-based series of twin pairs discordant for physical activity behavior. | Kujala UM et al. | β | 1999 | β |
| Genetic factors and osteoporotic fractures in elderly people: prospective 25 year follow up of a nationwide cohort of elderly Finnish twins. | Kannus P et al. | β | 1999 | β |
| Genetic predisposition, environment and cancer incidence: a nationwide twin study in Finland, 1976-1995. | Verkasalo PK et al. | β | 1999 | β |
| Migraine without aura: a population-based twin study. | Gervil M et al. | β | 1999 | β |
| Nightmares: familial aggregation and association with psychiatric disorders in a nationwide twin cohort. | Hublin C et al. | β | 1999 | β |
| The relative role of genetic and environmental factors in migraine without aura. | Gervil M et al. | β | 1999 | β |
| A population-based study of Graves' disease in Danish twins. | Brix TH et al. | β | 1998 | β |
| Epilepsies in twins: genetics of the major epilepsy syndromes. | Berkovic SF et al. | β | 1998 | β |
| Hay fever--a Finnish nationwide study of adolescent twins and their parents. | RΓ€sΓ€nen M et al. | β | 1998 | β |
| How heritable is individual susceptibility to death? The results of an analysis of survival data on Danish, Swedish and Finnish twins. | Iachine IA et al. | β | 1998 | β |
| Importance of genetic factors in adolescent asthma: a population-based twin-family study. | Laitinen T et al. | β | 1998 | β |
| Magnetic resonance imaging of cerebral central sulci: a study of monozygotic twins. | Bonan I et al. | β | 1998 | β |
| Serum lipids and apolipoprotein E phenotypes in identical twins reared apart. | Kervinen K et al. | β | 1998 | β |
| Serum lipids, lipoproteins, and lipid metabolizing enzymes in identical twins discordant for obesity. | RΓΆnnemaa T et al. | β | 1998 | β |
| Sleeptalking in twins: epidemiology and psychiatric comorbidity. | Hublin C et al. | β | 1998 | β |
| Validation of a telephone zygosity questionnaire in twins of known zygosity. | Peeters H et al. | β | 1998 | β |
| Are genetic determinants of weight gain modified by leisure-time physical activity? A prospective study of Finnish twins. | Heitmann BL et al. | β | 1997 | β |
| Lifetime exercise and disk degeneration: an MRI study of monozygotic twins. | Videman T et al. | β | 1997 | β |
| Mortality of adults with asthma: a prospective cohort study. | Huovinen E et al. | β | 1997 | β |
| Systematic identification of twins by computerised searches of NHS patient registers in the UK. | Strachan DP et al. | β | 1997 | β |
| Twins under shift work: a case study of sleep log data. | Fukuda K | β | 1997 | β |
| Alzheimer's disease in Finnish twins. | Raiha I et al. | β | 1996 | β |
| Cleft-twin sets in Finland 1948-1987. | NordstrΓΆm RE et al. | β | 1996 | β |
| Genetic and environmental components of interindividual variation in circulating levels of IGF-I, IGF-II, IGFBP-1, and IGFBP-3. | Harrela M et al. | β | 1996 | β |
| Twin births to mothers who are twins: a registry based study. | Lichtenstein P et al. | β | 1996 | β |
| Determinants of bone mass in 10- to 26-year-old females: a twin study. | Young D et al. | β | 1995 | β |
| Genetic, environmental, and phenotypic links between body mass index and blood pressure among women. | Allison DB et al. | β | 1995 | β |
| Genetic factors in the presence, severity, and triggers of asthma. | Sarafino EP et al. | β | 1995 | β |
| Occurrence of ankylosing spondylitis in a nationwide series of twins. | JΓ€rvinen P | β | 1995 | β |
| Relationship between obesity and concordance rate for type 2 (non-insulin-dependent) diabetes mellitus among twins. | Matsuda A et al. | β | 1994 | β |
| Twin studies in rheumatic diseases. | JΓ€rvinen P et al. | β | 1994 | β |
| Heritability of hostility-related emotions, attitudes, and behaviors. | Cates DS et al. | β | 1993 | β |
| Heritability of myopic refractive errors in identical and fraternal twins. | Angi MR et al. | β | 1993 | β |
| The premenstrual syndrome: a twin study. | Condon JT | β | 1993 | β |
| Zygosity diagnosis of twins by questionnaire for twins' mothers. | Ooki S et al. | β | 1993 | β |
| A revised estimate of twin concordance in systemic lupus erythematosus. | Deapen D et al. | β | 1992 | β |
| Concordance for type 1 (insulin-dependent) and type 2 (non-insulin-dependent) diabetes mellitus in a population-based cohort of twins in Finland. | Kaprio J et al. | β | 1992 | β |
| Consistency and change in patterns of social drinking: a 6-year follow-up of the Finnish Twin Cohort. | Kaprio J et al. | β | 1992 | β |
| Role of occupational exposure to airway irritants in the development of asthma. | Antti-Poika M et al. | β | 1992 | β |
| Systemic lupus erythematosus and related systemic diseases in a nationwide twin cohort: an increased prevalence of disease in MZ twins and concordance of disease features. | JΓ€rvinen P et al. | β | 1992 | β |
| Twin study on cup/disc ratio of the optic nerve head. | Teikari JM et al. | β | 1992 | β |
| A population-based study of bronchial asthma in adult twin pairs. | Nieminen MM et al. | β | 1991 | β |
| Back pain: a study of twins. | Bengtsson B et al. | β | 1991 | β |
| Genetic factors in epileptic seizures: evidence from a large twin population. | SillanpÀÀ M et al. | β | 1991 | β |
| Periodontal findings in adult twins. | Michalowicz BS et al. | β | 1991 | β |
| Body weight in the Finnish Twin Cohort. | Turula M et al. | β | 1990 | β |
| Cigarette smoking as a cause of lung cancer and coronary heart disease. A study of smoking-discordant twin pairs. | Kaprio J et al. | β | 1990 | β |
| Population-based twin registries: illustrative applications in genetic epidemiology and behavioral genetics from the Finnish Twin Cohort Study. | Kaprio J et al. | β | 1990 | β |
| Selection bias in disease-related twin studies. Data on 11,154 adult Finnish twin pairs from a nationwide panel. | Romanov K et al. | β | 1990 | β |
| Study of gene-environment effects on development of hyperopia: a study of 191 adult twin pairs from the Finnish Twin Cohort Study. | Teikari J et al. | β | 1990 | β |
| The Minnesota Twin Family Registry: some initial findings. | Lykken DT et al. | β | 1990 | β |
| Twin concordance for a binary trait: III. A bivariate analysis of hay fever and asthma. | Hopper JL et al. | β | 1990 | β |
| Zygosity diagnosis of twins by questionnaire. | Ooki S et al. | β | 1990 | β |
| Biliary lipid composition in monozygotic and dizygotic pairs of twins. | Antero KesΓ€niemi Y et al. | β | 1989 | β |
| Carotid arteriosclerosis in identical twins discordant for cigarette smoking. | Haapanen A et al. | β | 1989 | β |
| Determining zygosity in the Vietnam Era Twin Registry: an approach using questionnaires. | Eisen S et al. | β | 1989 | β |
| Evaluation of zygosity diagnosis in twin pairs below age seven by means of a mailed questionnaire. | BΓΈnnelykke B et al. | β | 1989 | β |
| Genetic and environmental factors in sciatica. Evidence from a nationwide panel of 9365 adult twin pairs. | HeikkilΓ€ JK et al. | β | 1989 | β |
| Multiple sclerosis and occupational exposure to chemicals: a co-twin control study of a nationwide series of twins. | Juntunen J et al. | β | 1989 | β |
| The contribution of HLA to rheumatoid arthritis. | Deighton CM et al. | β | 1989 | β |
| Twins, smoking and mortality: a 12-year prospective study of smoking-discordant twin pairs. | Kaprio J et al. | β | 1989 | β |
| Decreased beta-adrenergic receptor density and catecholamine response in male cigarette smokers. A study of monozygotic twin pairs discordant for smoking. | Laustiola KE et al. | β | 1988 | β |
| Frequency of social contact and intrapair resemblance of adult monozygotic cotwins--or does shared experience influence personality after all? | Rose RJ et al. | β | 1988 | β |
| Heritability estimate for refractive errors--a population-based sample of adult twins. | Teikari JM et al. | β | 1988 | β |
| Design and sampling considerations, response rates, and representativeness in a Finnish Twin Family Study. | Kaprio J et al. | β | 1987 | β |
| Genetic and environmental control of blood pressure in twins and their family members. | Tishler PV et al. | β | 1987 | β |
| Genetic factors in open-angle (simple and capsular) glaucoma. A population-based twin study. | Teikari JM | β | 1987 | β |
| Genetic influences on use and abuse of alcohol: a study of 5638 adult Finnish twin brothers. | Kaprio J et al. | β | 1987 | β |
| Inheritance of high density lipoprotein and lipoprotein lipase and hepatic lipase activity. | Kuusi T et al. | β | 1987 | β |
| Ophthalmic disease in twins: a nationwide record linkage study of hospital discharges and free medications for 16,067 twin pairs. | Teikari JM et al. | β | 1987 | β |
| Primary open-angle glaucoma in 2 monozygotic twin pairs. | Teikari JM et al. | β | 1987 | β |
| The Vietnam Era Twin (VET) Registry: method of construction. | Eisen S et al. | β | 1987 | β |
| Finnish twins reared apart. II: Validation of zygosity, environmental dissimilarity and weight and height. | Langinvainio H et al. | β | 1984 | β |
| Health related psychosocial correlates of neuroticism: a study of adult male twins in Finland. | Koskenvuo M et al. | β | 1984 | β |
| Psychiatric hospitalization in twins. | Koskenvuo M et al. | β | 1984 | β |
| Responses of blood glucose and serum insulin to peroral glucose load in normoglycemic twins. | KesΓ€niemi YA et al. | β | 1984 | β |
| The study of human twins in medical research. | Hrubec Z et al. | β | 1984 | β |
| A genetic component of the variance of N-acetoxy-2-acetylaminofluorene-induced DNA damage in mononuclear leukocytes determined by a twin study. | Pero RW et al. | β | 1983 | β |
| Predicting zygosity in Norwegian twin pairs born 1915-1960. | Magnus P et al. | β | 1983 | β |
| Contribution of familial factors to the occurrence of cancer before old age in twin veterans. | Hrubec Z et al. | β | 1982 | β |
| Genetics of autoantibodies in relation to disease. An epidemiological study of two population series. | Aho K et al. | β | 1982 | β |
| Diagnosis of twin zygosity by self-assessment and by genetic analysis. | King MC et al. | β | 1980 | β |
| On the heritability of serum high density lipoprotein in twins. | Sistonen P et al. | β | 1980 | β |
| Dependency of concordance probability on gene frequencies in genetic systems for the diagnosis of twin zygosity. A graphical presentation enabling the rapid, optimal choice of genetic system. | Sarna S et al. | β | 1979 | β |
| Optimization procedures in twin zygosity diagnosis by genetic markers. A cost-effectiveness analysis. | Sarna S et al. | β | 1979 | β |
| The determination of twin zygosity by means of a mailed questionnaire. | Torgersen S | β | 1979 | β |
| Basal cell carcinoma in identical twins. | Kaprio J et al. | β | 1978 | β |