Global burden of depressive disorders in the year 2000.
paper
Cited
Public
Unavailable
- Authors
- Ustün, T B; Ayuso-Mateos, J L; Chatterji, S; Mathers, C; Murray, C J L
- Year
- 2004
- Journal
- The British journal of psychiatry : the journal of mental science
- PMID
- 15123501
- DOI
- 10.1192/bjp.184.5.386
BACKGROUND: The initial Global Burden of Disease study found that depression was the fourth leading cause of disease burden, accounting for 3.7% of total disability adjusted life years (DALYs) in the world in 1990. AIMS: To present the new estimates of depression burden for the year 2000. METHOD: DALYs for depressive disorders in each world region were calculated, based on new estimates of mortality, prevalence, incidence, average age at onset, duration and disability severity. RESULTS: Depression is the fourth leading cause of disease burden, accounting for 4.4% of total DALYs in the year 2000, and it causes the largest amount of non-fatal burden, accounting for almost 12% of all total years lived with disability worldwide. CONCLUSIONS: These data on the burden of depression worldwide represent a major public health problem that affects patients and society.
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| "Down in the Sewers": Perceptions of Depression and Depression Care Among African American Men. | Hudson DL et al. | — | 2018 | → |
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| Estimation of the National Burden of Disease and Vulnerable Population Associated with Natural Disasters in Korea: Heavy Precipitation and Typhoon. | Han HJ et al. | — | 2018 | → |
| Extract of Euryale ferox Salisb exerts antidepressant effects and regulates autophagy through the adenosine monophosphate-activated protein kinase-UNC-51-like kinase 1 pathway. | Huang Z et al. | — | 2018 | → |
| Family History as an Important Factor for Stratifying Participants in Genetic Studies of Major Depression. | Zalar B et al. | — | 2018 | → |
| Family support: A possible buffer against disruptive events for individuals with and without remitted depression. | Manczak EM et al. | — | 2018 | → |
| Fusing Mobile Phone Sensing and Brain Imaging to Assess Depression in College Students | Huckins JF et al. | — | 2018 | — |
| Gender difference in the point prevalence, symptoms, comorbidity, and correlates of depression: findings from the Lagos State Mental Health Survey (LSMHS), Nigeria. | Adewuya AO et al. | — | 2018 | → |
| Gene-based analysis of genes related to neurotrophic pathway suggests association of BDNF and VEGFA with antidepressant treatment-response in depressed patients. | Kao CF et al. | — | 2018 | → |
| Inhibition of the G9a/GLP histone methyltransferase complex modulates anxiety-related behavior in mice. | Wang DY et al. | — | 2018 | → |
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| Loneliness and Depression Among Older Adults in Urban Subsidized Housing. | Gonyea JG et al. | — | 2018 | → |
| Mapping the central effects of (±)-ketamine and traxoprodil using pharmacological magnetic resonance imaging in awake rats. | Tang H et al. | — | 2018 | → |
| Microglial activation mediates chronic mild stress-induced depressive- and anxiety-like behavior in adult rats. | Wang YL et al. | — | 2018 | → |
| Molecular mechanism of noradrenaline during the stress-induced major depressive disorder. | Seki K et al. | — | 2018 | → |
| Multimodal early-life stress induces biological changes associated to psychopathologies. | Godoy LD et al. | — | 2018 | → |
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| On the rubidium and lithium content and availability in the sub-arid south-eastern Mediterranean: potential health implications. | Kot FS | — | 2018 | → |
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| Oxidatively-induced DNA damage and base excision repair in euthymic patients with bipolar disorder. | Ceylan D et al. | — | 2018 | → |
| Parenting mediates the impact of maternal depression on child internalizing symptoms. | Kuckertz JM et al. | — | 2018 | → |
| Predicting short term mood developments among depressed patients using adherence and ecological momentary assessment data. | Mikus A et al. | — | 2018 | → |
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| Severe depression and anxiety in women with overactive bladder. | Melotti IGR et al. | — | 2018 | → |
| Sonic hedgehog, Wnt, and brain-derived neurotrophic factor cell signaling pathway crosstalk: potential therapy for depression. | Tayyab M et al. | — | 2018 | → |
| Successful validation of the CAT-MH Scales in a sample of Latin American migrants in the United States and Spain. | Gibbons RD et al. | — | 2018 | → |
| The antidepressant effects of ɑ-tocopherol are related to activation of autophagy via the AMPK/mTOR pathway. | Huang X et al. | — | 2018 | → |
| The Changes of Functional Connectivity Strength in Electroconvulsive Therapy for Depression: A Longitudinal Study. | Wei Q et al. | — | 2018 | → |
| The effect of exercise on resting concentrations of peripheral brain-derived neurotrophic factor (BDNF) in major depressive disorder: A meta-analysis. | Dinoff A et al. | — | 2018 | → |
| The importance of TCF4 gene in the etiology of recurrent depressive disorders. | Mossakowska-Wójcik J et al. | — | 2018 | → |
| The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders. | Chang H et al. | — | 2018 | → |
| Understanding the pathophysiology of depression: From monoamines to the neurogenesis hypothesis model - are we there yet? | Jesulola E et al. | — | 2018 | → |
| Variability of the Prevalence of Depression in Function of Sociodemographic and Environmental Factors: Ecological Model. | Llorente JM et al. | — | 2018 | → |
| Variance of the global signal as a pretreatment predictor of antidepressant treatment response in drug-naïve major depressive disorder. | Zhu J et al. | — | 2018 | → |
| A comparative study of quality of life and marital satisfaction in patients with depression and their spouses. | Aggarwal S et al. | — | 2017 | → |
| Adaptive emotion regulation mediates the relationship between self-compassion and depression in individuals with unipolar depression. | Diedrich A et al. | — | 2017 | → |
| Association between depression and fruit and vegetable consumption among adults in South Asia. | Bishwajit G et al. | — | 2017 | → |
| Associations of Psychometric Affective Parameters with Urodynamic Investigation for Urinary Frequency. | Vrijens DMJ et al. | — | 2017 | → |
| Barriers and facilitators of adherence to antidepressants among outpatients with major depressive disorder: A qualitative study. | Ho SC et al. | — | 2017 | → |
| Blended care vs. usual care in the treatment of depressive symptoms and disorders in general practice [BLENDING]: study protocol of a non-inferiority randomized trial. | Massoudi B et al. | — | 2017 | → |
| Built Environment and Depression in Low-Income African Americans and Whites. | James P et al. | — | 2017 | → |
| Common variants in GRIK4 and major depressive disorder: An association study in the Chinese Han population. | Ren D et al. | — | 2017 | → |
| Cost-effectiveness of computerized cognitive-behavioural therapy for the treatment of depression in primary care: findings from the Randomised Evaluation of the Effectiveness and Acceptability of Computerised Therapy (REEACT) trial. | Duarte A et al. | — | 2017 | → |
| Cost-utility analysis of vortioxetine versus agomelatine, bupropion SR, sertraline and venlafaxine XR after treatment switch in major depressive disorder in Finland. | Soini E et al. | — | 2017 | → |
| Depression among Iranian nurses: A systematic review and meta-analysis. | Saeedi Shahri SS et al. | — | 2017 | → |
| Depression and anxiety symptoms are associated with white blood cell count and red cell distribution width: A sex-stratified analysis in a population-based study. | Shafiee M et al. | — | 2017 | → |
| Depression, Anxiety and Stress Among Higher Secondary School Students of Imphal, Manipur. | Kumar KS et al. | — | 2017 | → |
| Depression literacy in women attending university hospital clinics in Riyadh Saudi Arabia. | Siddiqui AR et al. | — | 2017 | → |
| Depression, suicidality, and alcohol use disorder among people living with HIV/AIDS in Nigeria. | Egbe CO et al. | — | 2017 | → |
| Depressive behavior induced by unpredictable chronic mild stress increases dentin hypersensitivity in rats. | Barbosa FM et al. | — | 2017 | → |
| Depressive symptoms in Chinese family caregivers of patients with heart failure: A cross-sectional study. | Hu X et al. | — | 2017 | → |
| Dietary patterns are associated with depressive symptoms among Chinese adults: a case-control study with propensity score matching. | Xia Y et al. | — | 2017 | → |
| Does Social Support Moderate the Association Among Major Depression, Generalized Anxiety Disorder, and Functional Disability in Adults With Diabetes? | Levy M et al. | — | 2017 | → |
| Do regional brain volumes and major depressive disorder share genetic architecture? A study of Generation Scotland (n=19 762), UK Biobank (n=24 048) and the English Longitudinal Study of Ageing (n=5766). | Wigmore EM et al. | — | 2017 | → |
| Effects of Yoga on Heart Rate Variability and Depressive Symptoms in Women: A Randomized Controlled Trial. | Chu IH et al. | — | 2017 | → |
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| Evidence for the treatment of moderate depression: a systematic review. | Aherne D et al. | — | 2017 | → |
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| Exercise for patients with major depression: a systematic review with meta-analysis and trial sequential analysis. | Krogh J et al. | — | 2017 | → |
| Exercise is an effective treatment for positive valence symptoms in major depression. | Toups M et al. | — | 2017 | → |
| Exposure to pesticide as a risk factor for depression: A population-based longitudinal study in Korea. | Koh SB et al. | — | 2017 | → |
| Gender and Age Effects on the Trajectory of Depression in Opioid Users during Methadone Maintenance Treatment. | Wang PW et al. | — | 2017 | → |
| Genetic effects influencing risk for major depressive disorder in China and Europe. | Bigdeli TB et al. | — | 2017 | → |
| Help from home for depression: A randomised controlled trial comparing internet-delivered cognitive behaviour therapy with bibliotherapy for depression. | Smith J et al. | — | 2017 | → |
| High-frequency repetitive transcranial magnetic stimulation over the left DLPFC for major depression: Session-dependent efficacy: A meta-analysis. | Teng S et al. | — | 2017 | → |
| Instability of default mode network connectivity in major depression: a two-sample confirmation study. | Wise T et al. | — | 2017 | → |
| Internet- and mobile-based depression interventions for people with diagnosed depression: A systematic review and meta-analysis. | Josephine K et al. | — | 2017 | → |
| Involvement of extracellular signal-regulated kinase (ERK) in the short and long-lasting antidepressant-like activity of NMDA receptor antagonists (zinc and Ro 25-6981) in the forced swim test in rats. | Pochwat B et al. | — | 2017 | → |
| Is There Any Difference Between Depression and Anxiety in Overactive Bladder According to Sex? A Systematic Review and Meta-Analysis. | Melotti IGR et al. | — | 2017 | → |
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| Making the cut: Depression screening in urban general hospital clinics for culturally diverse Latino populations. | Gutnick D et al. | — | 2017 | → |
| Mental health work in school health services and school nurses' involvement and attitudes, in a Norwegian context. | Skundberg-Kletthagen H et al. | — | 2017 | → |
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| Modulation of motor cortex excitability predicts antidepressant response to prefrontal cortex repetitive transcranial magnetic stimulation. | Oliveira-Maia AJ et al. | — | 2017 | → |
| Neuropsychological profiles of major depressive disorder and bipolar disorder during euthymia. A systematic literature review of comparative studies. | Szmulewicz AG et al. | — | 2017 | → |
| Obesity and depressive symptoms among Chinese people aged 45 and over. | Qian J et al. | — | 2017 | → |
| Preclinical Characterization of (<i>R</i>)-3-((3<i>S</i>,4<i>S</i>)-3-fluoro-4-(4-hydroxyphenyl)piperidin-1-yl)-1-(4-methylbenzyl)pyrrolidin-2-one (BMS-986169), a Novel, Intravenous, Glutamate <i>N</i>-Methyl-d-Aspartate 2B Receptor Negative Allosteric Modulator with Potential in Major Depressive Disorder. | Bristow LJ et al. | — | 2017 | → |
| Prevalence of depression and related social and physical factors amongst the Iranian elderly population in 2012. | Taheri Tanjanai P et al. | — | 2017 | → |
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| Proteomic investigation of the prefrontal cortex in the rat clomipramine model of depression. | Gellén B et al. | — | 2017 | → |
| Public attitudes toward depression and help-seeking: Impact of the OSPI-Europe depression awareness campaign in four European regions. | Kohls E et al. | — | 2017 | → |
| Role of Personality Functioning in the Quality of Life of Patients with Depression. | Crempien C et al. | — | 2017 | → |
| Seasonal Bushmeat Hunger in the Congo Basin. | Dounias E et al. | — | 2017 | → |
| Self-compassion mediates the link between dependency and depressive symptomatology in college students. | Denckla CA et al. | — | 2017 | → |
| Serum ApoB levels in depressive patients: associated with cognitive deficits. | Hui L et al. | — | 2017 | → |
| Sex differences modulating serotonergic polymorphisms implicated in the mechanistic pathways of risk for depression and related disorders. | Perry LM et al. | — | 2017 | → |
| Smartphone-Based Monitoring of Objective and Subjective Data in Affective Disorders: Where Are We and Where Are We Going? Systematic Review. | Dogan E et al. | — | 2017 | → |
| Study protocol for a randomised pragmatic trial comparing the clinical and cost effectiveness of lithium and quetiapine augmentation in treatment resistant depression (the LQD study). | Marwood L et al. | — | 2017 | → |
| The association of depression at any time to the risk of death following coronary artery disease diagnosis. | May HT et al. | — | 2017 | → |
| The effects of combined sertraline and aspirin therapy on depression severity among patients with major depressive disorder: A randomized clinical trial. | Sepehrmanesh Z et al. | — | 2017 | → |
| The Prevalence of Depression and Depressive Symptoms among Eye Disease Patients: A Systematic Review and Meta-analysis. | Zheng Y et al. | — | 2017 | → |
| Therapeutic Response to Paroxetine in Major Depressive Disorder Predicted by DNA Methylation. | Takeuchi N et al. | — | 2017 | → |
| The role of bullying in depressive symptoms from adolescence to emerging adulthood: A growth mixture model. | Hill RM et al. | — | 2017 | → |
| The role of unhealthy lifestyles in the incidence and persistence of depression: a longitudinal general population study in four emerging countries. | Cabello M et al. | — | 2017 | → |
| Translocator Protein-18 kDa (TSPO) Positron Emission Tomography (PET) Imaging and Its Clinical Impact in Neurodegenerative Diseases. | Dupont AC et al. | — | 2017 | → |
| Which DSM validated tools for diagnosing depression are usable in primary care research? A systematic literature review. | Nabbe P et al. | — | 2017 | → |
| Workplace mental health programmes: the role of managers. | Greden JF | — | 2017 | → |
| An association of AKT1 gene polymorphism with antidepressant treatment response. | Losenkov IS et al. | — | 2016 | → |
| An Internet-Based Intervention for Depression in Primary Care in Spain: A Randomized Controlled Trial. | Montero-Marín J et al. | — | 2016 | → |
| Are Sensory Processing Features Associated with Depressive Symptoms in Boys with an ASD? | Bitsika V et al. | — | 2016 | → |
| Association between Serum Ferritin Concentrations and Depressive Symptoms among Chinese Adults: A Population Study from the Tianjin Chronic Low-Grade Systemic Inflammation and Health (TCLSIHealth) Cohort Study. | Su Q et al. | — | 2016 | → |
| Association between Suicide Ideation and Attempts and Being an Immigrant among Adolescents, and the Role of Socioeconomic Factors and School, Behavior, and Health-Related Difficulties. | Chau K et al. | — | 2016 | → |
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| Clinical, Functional, and Biological Correlates of Cognitive Dimensions in Major Depressive Disorder - Rationale, Design, and Characteristics of the Cognitive Function and Mood Study (CoFaM-Study). | Baune BT et al. | — | 2016 | → |
| Deactivation in anterior cingulate cortex during facial processing in young individuals with high familial risk and early development of depression: fMRI findings from the Scottish Bipolar Family Study. | Chan SW et al. | — | 2016 | → |
| Depression and Inflammatory Periodontal Disease Considerations-An Interdisciplinary Approach. | Dumitrescu AL | — | 2016 | → |
| Depression is associated with increased incidence of osteoporotic thoracolumbar fracture in postmenopausal women: a prospective study. | Zong Y et al. | — | 2016 | → |
| Diabetes and Quality of Life: Initial Approach to Depression, Physical Activity, and Sexual Dysfunction. | Pozzo MJ et al. | — | 2016 | → |
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| EEG marker of inhibitory brain activity correlates with resting-state cerebral blood flow in the reward system in major depression. | Cantisani A et al. | — | 2016 | → |
| Effectiveness and cost-effectiveness of a self-management training for patients with chronic and treatment resistant anxiety or depressive disorders: design of a multicenter randomized controlled trial. | Zoun MH et al. | — | 2016 | → |
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| Efficacy and safety of multiple doses of levomilnacipran extended-release for the treatment of major depressive disorder. | Huang Q et al. | — | 2016 | → |
| Electroconvulsive therapy increases temporal gray matter volume and cortical thickness. | Sartorius A et al. | — | 2016 | → |
| Energetic stress: The reciprocal relationship between energy availability and the stress response. | Harrell CS et al. | — | 2016 | → |
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| Health, Social, and Economic Variables Associated with Depression Among Older People in Low and Middle Income Countries: World Health Organization Study on Global AGEing and Adult Health. | Brinda EM et al. | — | 2016 | → |
| Increasing access to Cognitive Behaviour Therapy in Low and Middle Income Countries: A strategic framework. | Beck A et al. | — | 2016 | → |
| International Classification of Diseases 10th edition-based disability adjusted life years for measuring of burden of specific injury. | Kim YJ et al. | — | 2016 | → |
| Major depressive disorder and suicidal behavior among urban dwelling Ethiopian adult outpatients at a general hospital. | Whittier AB et al. | — | 2016 | → |
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| Neural Correlates of Antidepressant Treatment Response in Adolescents with Major Depressive Disorder. | Cullen KR et al. | — | 2016 | → |
| NUT CONSUMPTION IS ASSOCIATED WITH DEPRESSIVE SYMPTOMS AMONG CHINESE ADULTS. | Su Q et al. | — | 2016 | → |
| Omega-3 polyunsaturated fatty acid supplementation and white matter changes in major depression. | Chhetry BT et al. | — | 2016 | → |
| Polymorphism of rs3813034 in Serotonin Transporter Gene SLC6A4 Is Associated With the Selective Serotonin and Serotonin-Norepinephrine Reuptake Inhibitor Response in Depressive Disorder: Sequencing Analysis of SLC6A4. | Nonen S et al. | — | 2016 | → |
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| Psychiatric Illness Is Common Among Patients with Orthopaedic Polytrauma and Is Linked with Poor Outcomes. | Weinberg DS et al. | — | 2016 | → |
| Psychometric validation of the 16 Item Quick Inventory of Depressive Symptomatology Self-Report Version (QIDS-SR16) in military veterans with PTSD. | Surís A et al. | — | 2016 | → |
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| Quality Over Quantity: Integrating Mental Health Assessment Tools into Primary Care Practice. | Hudson DL | — | 2016 | → |
| Racial Discrimination, John Henryism, and Depression Among African Americans. | Hudson DL et al. | — | 2016 | → |
| Relatives of Inpatients Suffering from Severe Depression: Their Burden and Encounters with the Psychiatric Health Services. | Skundberg-Kletthagen H et al. | — | 2016 | → |
| Risk of major depressive disorder among older persons living in HIV-endemic central and southwestern Uganda. | Kinyanda E et al. | — | 2016 | → |
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| Study the effects of saffron on depression and lipid profiles: A double blind comparative study. | Sahraian A et al. | — | 2016 | → |
| The Cox-2 Inhibitor Meloxicam Ameliorates Neuroinflammation and Depressive Behavior in Adult Mice after Splenectomy. | Haile M et al. | — | 2016 | → |
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| THE LONG-TERM EFFICACY OF ACUTE-PHASE PSYCHOTHERAPY FOR DEPRESSION: A META-ANALYSIS OF RANDOMIZED TRIALS. | Karyotaki E et al. | — | 2016 | → |
| The relationship of self-compassion and depression: Cross-lagged panel analyses in depressed patients after outpatient therapy. | Krieger T et al. | — | 2016 | → |
| Time-dependent effects of dexamethasone plasma concentrations on glucocorticoid receptor challenge tests. | Menke A et al. | — | 2016 | → |
| Transactions in Suffering: Mothers, Daughters, and Chronic Disease Comorbidities in New Delhi, India. | Weaver LJ | — | 2016 | → |
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| Two standardized fractions of Gardenia jasminoides Ellis with rapid antidepressant effects are differentially associated with BDNF up-regulation in the hippocampus. | Ren L et al. | — | 2016 | → |
| Wealth and Disability in Later Life: The English Longitudinal Study of Ageing (ELSA). | Torres JL et al. | — | 2016 | → |
| A Canadian Primary Care Sentinel Surveillance Network Study Evaluating Antidepressant Prescribing in Canada From 2006 to 2012. | Morkem R et al. | — | 2015 | → |
| Affective symptoms and the overactive bladder - a systematic review. | Vrijens D et al. | — | 2015 | → |
| A history of early life parental loss or separation is associated with successful cognitive-behavioral therapy in major depressive disorder. | Niciu MJ et al. | — | 2015 | → |
| Altered insular activation and increased insular functional connectivity during sad and happy face processing in adolescent major depressive disorder. | Henje Blom E et al. | — | 2015 | → |
| An Act of Balance Between Adaptive and Maladaptive Immunity in Depression: a Role for T Lymphocytes. | Toben C et al. | — | 2015 | → |
| An Online Health Prevention Intervention for Youth with Addicted or Mentally Ill Parents: Experiences and Perspectives of Participants and Providers from a Randomized Controlled Trial. | Woolderink M et al. | — | 2015 | → |
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| Antidepression medication improves quality of life in elderly patients with benign prostatic hyperplasia and depression. | Ma L et al. | — | 2015 | → |
| A possible link between early probiotic intervention and the risk of neuropsychiatric disorders later in childhood: a randomized trial. | Pärtty A et al. | — | 2015 | → |
| A review of the bioactivity of coffee, caffeine and key coffee constituents on inflammatory responses linked to depression. | Hall S et al. | — | 2015 | → |
| Association between pain severity, depression severity, and use of health care services in Japan: results of a nationwide survey. | Vietri J et al. | — | 2015 | → |
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| Characterization of depression among patients at urban primary healthcare centers in Oman. | Al-Salmani A et al. | — | 2015 | → |
| Childhood adversity, depression, age and gender effects on white matter microstructure: a DTI study. | Ugwu ID et al. | — | 2015 | → |
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| Depression among patients with tuberculosis: determinants, course and impact on pathways to care and treatment outcomes in a primary care setting in southern Ethiopia--a study protocol. | Ambaw F et al. | — | 2015 | → |
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| Depression, Stress, Quality of Life, and Dry Eye Disease in Korean Women: A Population-Based Study. | Na KS et al. | — | 2015 | → |
| Depressive disorder in pregnant Latin women: does intimate partner violence matter? | Fonseca-Machado Mde O et al. | — | 2015 | → |
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| Disorder-specific versus transdiagnostic and clinician-guided versus self-guided treatment for major depressive disorder and comorbid anxiety disorders: A randomized controlled trial. | Titov N et al. | — | 2015 | → |
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| Expanding the efficacy of Project UPLIFT: Distance delivery of mindfulness-based depression prevention to people with epilepsy. | Thompson NJ et al. | — | 2015 | → |
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| How does the ICD-10 symptom rating (ISR) with four items assess depression compared to the BDI-II? A validation study. | Brandt WA et al. | — | 2015 | → |
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| Decreased occipital cortical glutamate levels in response to successful cognitive-behavioral therapy and pharmacotherapy for major depressive disorder. | Abdallah CG et al. | — | 2014 | → |
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| Depression treatment by withdrawal of short-term low-dose antipsychotic, a proof-of-concept randomized double-blind study. | Kennedy SH et al. | — | 2014 | → |
| Discriminating risk and resilience endophenotypes from lifetime illness effects in familial major depressive disorder. | Peterson BS et al. | — | 2014 | → |
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| GPR39 (zinc receptor) knockout mice exhibit depression-like behavior and CREB/BDNF down-regulation in the hippocampus. | Młyniec K et al. | — | 2014 | → |
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| Psychometric Properties of the Attitudes toward Self-Revised in Italian Young Adults. | Innamorati M et al. | — | 2013 | → |
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