Liquid biopsy: monitoring cancer-genetics in the blood.
- Authors
- Crowley, Emily; Di Nicolantonio, Federica; Loupakis, Fotios; Bardelli, Alberto
- Year
- 2013
- Journal
- Nature reviews. Clinical oncology
- PMID
- 23836314
- DOI
- 10.1038/nrclinonc.2013.110
Cancer is associated with mutated genes, and analysis of tumour-linked genetic alterations is increasingly used for diagnostic, prognostic and treatment purposes. The genetic profile of solid tumours is currently obtained from surgical or biopsy specimens; however, the latter procedure cannot always be performed routinely owing to its invasive nature. Information acquired from a single biopsy provides a spatially and temporally limited snap-shot of a tumour and might fail to reflect its heterogeneity. Tumour cells release circulating free DNA (cfDNA) into the blood, but the majority of circulating DNA is often not of cancerous origin, and detection of cancer-associated alleles in the blood has long been impossible to achieve. Technological advances have overcome these restrictions, making it possible to identify both genetic and epigenetic aberrations. A liquid biopsy, or blood sample, can provide the genetic landscape of all cancerous lesions (primary and metastases) as well as offering the opportunity to systematically track genomic evolution. This Review will explore how tumour-associated mutations detectable in the blood can be used in the clinic after diagnosis, including the assessment of prognosis, early detection of disease recurrence, and as surrogates for traditional biopsies with the purpose of predicting response to treatments and the development of acquired resistance.
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| Update on Neoadjuvant and Adjuvant BRAF Inhibitors in Papillary Craniopharyngioma: A Systematic Review. | Cossu G et al. | โ | 2024 | โ |
| Waiting for the "liquid revolution" in the adjuvant treatment of colon cancer patients: a review of ongoing trials. | Conca V et al. | โ | 2024 | โ |
| A Comprehensive Review of the Potential Role of Liquid Biopsy as a Diagnostic, Prognostic, and Predictive Biomarker in Pancreatic Ductal Adenocarcinoma. | Stosic K et al. | โ | 2023 | โ |
| Advances in application of circulating tumor DNA in ovarian cancer. | Xia T et al. | โ | 2023 | โ |
| Aggregation enhanced fluorescence and Raman signals for highly sensitive cancer detection. | Guan R et al. | โ | 2023 | โ |
| A Microfluidic Approach for Enrichment and Single-Cell Characterization of Circulating Tumor Cells from Peripheral Blood. | Radfar P et al. | โ | 2023 | โ |
| [Analysis of the feasibility and prognostic value of circulating tumor DNA monitoring in detecting gene mutations in patients with diffuse large B-cell lymphoma receiving chimeric antigen receptor T-cell therapy]. | Zhou LH et al. | โ | 2023 | โ |
| An inexpensive semi-automated sample processing pipeline for cell-free RNA extraction. | Moufarrej MN et al. | โ | 2023 | โ |
| An integrated lab-on-a-chip platform for pre-concentration and detection of colorectal cancer exosomes using anti-CD63 aptamer as a recognition element. | Chinnappan R et al. | โ | 2023 | โ |
| A novel platform using homobifunctional hydrazide for enrichment and isolation of urinary circulating RNAs. | Koo B et al. | โ | 2023 | โ |
| An Overview of Hepatocellular Carcinoma Surveillance Focusing on Non-Cirrhotic NAFLD Patients: A Challenge for Physicians. | Cespiati A et al. | โ | 2023 | โ |
| Application of serum Raman spectroscopy combined with classification model for rapid breast cancer screening. | Lin R et al. | โ | 2023 | โ |
| Application of the Multi-Omics Liquid Biopsy Method M2P-HCC in Early Liver Cancer Screening for High-Risk Individuals with Hepatitis B-Related Liver Cancer. | Yu X et al. | โ | 2023 | โ |
| A test of miR-128-3p and miR-33a-5p in serum exosome as biomarkers for auxiliary diagnosis of non-small cell lung cancer. | Li M et al. | โ | 2023 | โ |
| Biological Stratification of Invasive and Advanced Urothelial Carcinoma. | Reike MJ et al. | โ | 2023 | โ |
| Bridging biological cfDNA features and machine learning approaches. | Moser T et al. | โ | 2023 | โ |
| Bronchoalveolar Lavage as Potential Diagnostic Specimens to Genetic Testing in Advanced Nonsmall Cell Lung Cancer. | Lin X et al. | โ | 2023 | โ |
| Can Liquid Biopsy Based on ctDNA/cfDNA Replace Tissue Biopsy for the Precision Treatment of EGFR-Mutated NSCLC? | Li YZ et al. | โ | 2023 | โ |
| Cell-free RNA for the liquid biopsy of gastrointestinal cancer. | Xing S et al. | โ | 2023 | โ |
| Characterization of Mitochondrial DNA Methylation of Alzheimer's Disease in Plasma Cell-Free DNA. | Ding B et al. | โ | 2023 | โ |
| Circulating miRNA as a Biomarker in Oral Cancer Liquid Biopsy. | Roi A et al. | โ | 2023 | โ |
| Circulating Tumor Cells as a Promising Tool for Early Detection of Hepatocellular Carcinoma. | Salehi M et al. | โ | 2023 | โ |
| Circulating tumor cells as potential prognostic biomarkers for early-stage pancreatic cancer: A systematic review and meta-analysis. | Zhang ZH et al. | โ | 2023 | โ |
| Circulating Tumor DNA and Management of Colorectal Cancer. | Krell M et al. | โ | 2023 | โ |
| Circulating Tumor DNA in the Management of Early-Stage Breast Cancer. | Vlataki K et al. | โ | 2023 | โ |
| Circulating Tumor DNA Is a Variant of Liquid Biopsy with Predictive and Prognostic Clinical Value in Breast Cancer Patients. | Zavarykina TM et al. | โ | 2023 | โ |
| Circulating tumor nucleic acids: biology, release mechanisms, and clinical relevance. | Stejskal P et al. | โ | 2023 | โ |
| Clinical Utility and Application of Liquid Biopsy Genotyping in Lung Cancer: A Comprehensive Review. | Nigro MC et al. | โ | 2023 | โ |
| Comparative analysis of genomic profiles between tissue-based and plasma-based next-generation sequencing in patients with non-small cell lung cancer. | Lin Z et al. | โ | 2023 | โ |
| Convenient exosome separation by phosphatidylserine targeting polymer brush materials. | Li S et al. | โ | 2023 | โ |
| Convergence of Precision Oncology and Liquid Biopsy in Non-Small Cell Lung Cancer. | Al-Obeidi E et al. | โ | 2023 | โ |
| Conversion of specific lncRNAs to biomarkers in exhaled breath condensate samples of patients with advanced stage non-small-cell lung cancer. | Tetik Vardarlฤฑ A et al. | โ | 2023 | โ |
| ctDNA as a novel and promising approach for cancer diagnosis: a focus on hepatocellular carcinoma. | Biglari N et al. | โ | 2023 | โ |
| Current advances of liquid biopsies in prostate cancer: Molecular biomarkers. | Alahdal M et al. | โ | 2023 | โ |
| Current research status of tumor cell biomarker detection. | Jiang L et al. | โ | 2023 | โ |
| Current status of molecular diagnostic approaches using liquid biopsy. | Takahashi K et al. | โ | 2023 | โ |
| Detection of Cancer-Associated Gene Mutations in Urinary Cell-Free DNA among Prostate Cancer Patients in South Africa. | Temilola DO et al. | โ | 2023 | โ |
| Detection of resistance mutations in patients with anaplastic lymphoma kinase-rearranged lung cancer through liquid biopsy. | Sasaki T et al. | โ | 2023 | โ |
| Droplet Digital PCR as a Molecular Tool for the Detection of the <i>EGFR</i> T790M Mutation in NSCLC Patients with the <i>EGFR</i> Activating Mutations. | Durgut S et al. | โ | 2023 | โ |
| Efficient and accurate KRAS genotyping using digital PCR combined with melting curve analysis for ctDNA from pancreatic cancer patients. | Tanaka J et al. | โ | 2023 | โ |
| EGFR mutation testing from pleural effusions of non-small cell lung cancer patients at the institute for oncology and radiology of Serbia. | Vukovic M et al. | โ | 2023 | โ |
| Electrochemical Biosensors for Whole Blood Analysis: Recent Progress, Challenges, and Future Perspectives. | Li S et al. | โ | 2023 | โ |
| Emerging Applications of Liquid Biopsies in Ovarian Cancer. | Chauhan US et al. | โ | 2023 | โ |
| Enhancing clinical potential of liquid biopsy through a multi-omic approach: A systematic review. | Di Sario G et al. | โ | 2023 | โ |
| Estimation of ALU Repetitive Elements in Plasma as a Cost-Effective Liquid Biopsy Tool for Disease Prognosis in Breast Cancer. | Nair MG et al. | โ | 2023 | โ |
| Evaluation of circulating tumor DNA by electropherogram analysis and methylome profiling in high-risk neuroblastomas. | Trinidad EM et al. | โ | 2023 | โ |
| Evaluation of <i>RAS</i> Mutational Status in Liquid Biopsy to Monitor Disease Progression in Metastatic Colorectal Cancer Patients. | Lastraioli E et al. | โ | 2023 | โ |
| Expert Consensus Recommendations on Biomarker Testing in Metastatic and Nonmetastatic NSCLC in Asia. | Mitsudomi T et al. | โ | 2023 | โ |
| Exploring circular MET RNA as a potential biomarker in tumors exhibiting high MET activity. | Bersani F et al. | โ | 2023 | โ |
| Fabrication of Multilayer Microfluidic Arrays for Passive, Efficient DNA Trapping and Profiling. | O'Keefe CM et al. | โ | 2023 | โ |
| Gastric juice non-coding RNAs as potential biomarkers for gastric cancer. | Gareev I et al. | โ | 2023 | โ |
| Genetic profiling of hormone-sensitive and castration-resistant prostate cancers and identification of genetic mutations prone to castration-resistant prostate cancer. | Wang Z et al. | โ | 2023 | โ |
| Genetics of Hepatocellular Carcinoma: From Tumor to Circulating DNA. | Campani C et al. | โ | 2023 | โ |
| Heterogeneity of the tumor immune microenvironment and clinical interventions. | Jin Z et al. | โ | 2023 | โ |
| Higher 13-Gene-Estimated TMB Detected from Plasma ctDNA is Associated with Worse Outcome for T-Cell Lymphoma Patients. | Chen C et al. | โ | 2023 | โ |
| High-purity isolation platelets by gradient centrifugation plus filtration. | Jin J et al. | โ | 2023 | โ |
| Identification of TP53 mutations in circulating tumour DNA in high grade serous ovarian carcinoma using next generation sequencing technologies. | Calapre L et al. | โ | 2023 | โ |
| Imaging and AI based chromatin biomarkers for diagnosis and therapy evaluation from liquid biopsies. | Challa K et al. | โ | 2023 | โ |
| Immune inhibitory receptor-mediated immune response, metabolic adaptation, and clinical characterization in patients with COVID-19. | An H et al. | โ | 2023 | โ |
| Integrated pipeline for ultrasensitive protein detection in cancer nanomedicine. | Cheng CA et al. | โ | 2023 | โ |
| In vivo flow cytometry reveals an anti-metastatic effect of Rujifang in triple-negative breast cancer. | Zhang F et al. | โ | 2023 | โ |
| Isolation, Detection and Analysis of Circulating Tumour Cells: A Nanotechnological Bioscope. | Das U et al. | โ | 2023 | โ |
| Latest advances and perspectives of liquid biopsy for cancer diagnostics driven by microfluidic on-chip assays. | Xie Y et al. | โ | 2023 | โ |
| Liquid Biopsy in Alzheimer's Disease Patients Reveals Epigenetic Changes in the <i>PRLHR</i> Gene. | Macรญas M et al. | โ | 2023 | โ |
| Liquid Biopsy in Lung Cancer: Biomarkers for the Management of Recurrence and Metastasis. | Souza VGP et al. | โ | 2023 | โ |
| Liquid biopsy using cell-free DNA in the early diagnosis of hepatocellular carcinoma. | Hu S et al. | โ | 2023 | โ |
| Multiplex Digital Methylation-Specific PCR for Noninvasive Screening of Lung Cancer. | Zhao Y et al. | โ | 2023 | โ |
| Multi-Targeting Nano-Systems Targeting Heterogeneous Cancer Cells for Therapeutics and Biomarker Detection. | Ren XH et al. | โ | 2023 | โ |
| New, fast and cheap prediction tests for BRCA1 gene mutations identification in clinical samples. | Gajda-Walczak A et al. | โ | 2023 | โ |
| Non-invasive detection of tumor markers in salivary extracellular vesicles based on digital PCR chips. | Qu Y et al. | โ | 2023 | โ |
| Nrf2, A Target for Precision Oncology in Cancer Prognosis and Treatment. | Ngo HKC et al. | โ | 2023 | โ |
| Nurturing the marriages of urinary liquid biopsies and nano-diagnostics for precision urinalysis of prostate cancer. | Liao C et al. | โ | 2023 | โ |
| Practical Application of Circulating Tumor-Related DNA of Human Papillomavirus in Liquid Biopsy to Evaluate the Molecular Response in Patients with Oropharyngeal Cancer. | Mazurek AM et al. | โ | 2023 | โ |
| Prognostic and predictive role of liquid biopsy in lung cancer patients. | Goksel T et al. | โ | 2023 | โ |
| Prognostic Role of Circulating Tumor Cell Trajectories in Metastatic Colorectal Cancer. | Magri V et al. | โ | 2023 | โ |
| Rapid metabolomic screening of cancer cells via high-throughput static droplet microfluidics. | Radfar P et al. | โ | 2023 | โ |
| Recent advances in plasmon-enhanced luminescence for biosensing and bioimaging. | Gao S et al. | โ | 2023 | โ |
| Recent advances in tumor biomarker detection by lanthanide upconversion nanoparticles. | Zhan Y et al. | โ | 2023 | โ |
| Recent progress in aptamer-based microfluidics for the detection of circulating tumor cells and extracellular vesicles. | Sun D et al. | โ | 2023 | โ |
| Role of extracellular vesicle in human papillomavirus-associated cervical cancer. | Dong S et al. | โ | 2023 | โ |
| Study on the detection method of biological characteristics of hepatoma cells based on terahertz time-domain spectroscopy. | Guan H et al. | โ | 2023 | โ |
| Surface-enhanced Raman spectroscopy for the characterization of different anatomical subtypes of oral cavity cancer. | Amber A et al. | โ | 2023 | โ |
| The Clinical Significance of Circulating Tumor DNA for Minimal Residual Disease Identification in Early-Stage Non-Small Cell Lung Cancer. | Verlicchi A et al. | โ | 2023 | โ |
| The current status and trends of DNA extraction. | Ye X et al. | โ | 2023 | โ |
| The emergence of RAS mutations in patients with RAS wild-type mCRC receiving cetuximab as first-line treatment: a noninterventional, uncontrolled multicenter study. | Tsai HL et al. | โ | 2023 | โ |
| The Emerging Role of Liquid Biopsies in Revolutionising Cancer Diagnosis and Therapy. | Shegekar T et al. | โ | 2023 | โ |
| The role of fibroblast growth factor 18 in cancers: functions and signaling pathways. | Zhou Y et al. | โ | 2023 | โ |
| The Use of ctDNA in the Diagnosis and Monitoring of Hepatocellular Carcinoma-Literature Review. | Kopystecka A et al. | โ | 2023 | โ |
| Accelerated Digital Biodetection Using Magneto-plasmonic Nanoparticle-Coupled Photonic Resonator Absorption Microscopy. | Che C et al. | โ | 2022 | โ |
| Acoustic Array Biochip Combined with Allele-Specific PCR for Multiple Cancer Mutation Analysis in Tissue and Liquid Biopsy. | Naoumi N et al. | โ | 2022 | โ |
| Advances in Microfluidics for the Implementation of Liquid Biopsy in Clinical Routine. | Teixeira A et al. | โ | 2022 | โ |
| Affinity-Based Enrichment of Extracellular Vesicles with Lipid Nanoprobes. | Wan Y et al. | โ | 2022 | โ |
| Analytical and clinical validation of an amplicon-based next generation sequencing assay for ultrasensitive detection of circulating tumor DNA. | Poh J et al. | โ | 2022 | โ |
| An Exosome-based Transcriptomic Signature for Noninvasive, Early Detection of Patients With Pancreatic Ductal Adenocarcinoma: A Multicenter Cohort Study. | Nakamura K et al. | โ | 2022 | โ |
| Antenna-enhanced mid-infrared detection of extracellular vesicles derived from human cancer cell cultures. | Temperini ME et al. | โ | 2022 | โ |
| Application of ddPCR in detection of the status and abundance of EGFR T790M mutation in the plasma samples of non-small cell lung cancer patients. | Zhang H et al. | โ | 2022 | โ |
| Ascites and Serial Plasma Circulating Tumor DNA for Predicting the Effectiveness of Hyperthermic Intraperitoneal Chemotherapy in Patients With Peritoneal Carcinomatosis. | Pu X et al. | โ | 2022 | โ |
| Assessment of cell-free DNA (cfDNA) concentrations in the perioperative period can predict risk of recurrence in patients with non-metastatic breast cancer. | Hassan F et al. | โ | 2022 | โ |
| A systematic review and meta-analysis of circulating cell-free DNA as a diagnostic biomarker for non-small cell lung cancer. | He X et al. | โ | 2022 | โ |
| Attogram-level light-induced antigen-antibody binding confined in microflow. | Iida T et al. | โ | 2022 | โ |
| Bimetallic Metal-Organic Framework Fe/Co-MIL-88(NH<sub>2</sub>) Exhibiting High Peroxidase-like Activity and Its Application in Detection of Extracellular Vesicles. | Jiang Q et al. | โ | 2022 | โ |
| Blood-based liquid biopsy: Insights into early detection and clinical management of lung cancer. | Liu C et al. | โ | 2022 | โ |
| Blood platelets as an RNA biomarker platform for neuro-oncological diseases. | Post E et al. | โ | 2022 | โ |
| Cancer-cell-derived cell-free DNA can predict distant metastasis earlier in pancreatic cancer: a prospective cohort study. | Huang CJ et al. | โ | 2022 | โ |
| CDC6: A novel canine tumour biomarker detected in circulating extracellular vesicles. | Andriessen A et al. | โ | 2022 | โ |
| Circulating Cell Free DNA and DNA Integrity Index as Discriminating Tools between Breast Cancer and Benign Breast Disease. | Elhelaly R et al. | โ | 2022 | โ |
| Circulating Exosomal microRNAs as Predictive Biomarkers of Neoadjuvant Chemotherapy Response in Breast Cancer. | Todorova VK et al. | โ | 2022 | โ |
| Clinical significance of circulating tumor cells after chemotherapy in unresectable pancreatic ductal adenocarcinoma. | Kim H et al. | โ | 2022 | โ |
| Clinical translation of patient-derived tumour organoids- bottlenecks and strategies. | Foo MA et al. | โ | 2022 | โ |
| Clinical validation of a spectroscopic liquid biopsy for earlier detection of brain cancer. | Cameron JM et al. | โ | 2022 | โ |
| Clinical Validation of Companion Diagnostics for the Selection of Patients with Non-Small Cell Lung Cancer Tumors Harboring Epidermal Growth Factor Receptor Exon 20 Insertion Mutations for Treatment with Amivantamab. | Jatkoe T et al. | โ | 2022 | โ |
| Comparative analysis of capture methods for genomic profiling of circulating tumor cells in colorectal cancer. | Alves JM et al. | โ | 2022 | โ |
| Comprehensive analysis of NGS and ARMS-PCR for detecting EGFR mutations based on 4467 cases of NSCLC patients. | He C et al. | โ | 2022 | โ |
| Concordance of Cytological Specimens with Histological Tissue for Detection of Epidermal Growth Factor Receptor Mutation in Non-Small Cell Lung Cancer: A Systematic Review. | Chua TH et al. | โ | 2022 | โ |
| Controversies in the Interpretation of Liquid Biopsy Data in Lymphoma. | Pirosa MC et al. | โ | 2022 | โ |
| Current and Emerging Technologies for the Analysis of the Genome-Wide and Locus-Specific DNA Methylation Patterns. | Tost J | โ | 2022 | โ |
| Current Status, Opportunities, and Challenges of Exosomes in Oral Cancer Diagnosis and Treatment. | Liu H et al. | โ | 2022 | โ |
| Detection of circulating <i>KRAS</i> mutant DNA in extracellular vesicles using droplet digital PCR in patients with colon cancer. | Choi J et al. | โ | 2022 | โ |
| Detection of mRNAs of Ribosomal Protein L15 and E-Cadherin in Living Circulating Tumor Cells at Single Cell Resolution To Study Tumor Heterogeneity. | Xu C et al. | โ | 2022 | โ |
| Development of cellulosic material-based microchannel device capable of fluorescence immunoassay of microsamples. | Shin J et al. | โ | 2022 | โ |
| Diagnostic performance of circulating tumor DNA as a minimally invasive biomarker for hepatocellular carcinoma: a systematic review and meta-analysis. | Li JJ et al. | โ | 2022 | โ |
| Diffuse large B-cell lymphoma and new insights into its pathobiology and implication in treatment. | Mamgain G et al. | โ | 2022 | โ |
| Digital Decoding of Single Extracellular Vesicle Phenotype Differentiates Early Malignant and Benign Lung Lesions. | Li J et al. | โ | 2022 | โ |
| Direct capture and sequencing reveal ultra-short single-stranded DNA in biofluids. | Cheng LY et al. | โ | 2022 | โ |
| Discovery and characterization of circulating tumor cell clusters in neuroendocrine tumor patients using nanosubstrate-embedded microchips. | Sun N et al. | โ | 2022 | โ |
| Early Detection of Pancreatic Cancers Using Liquid Biopsies and Hierarchical Decision Structure. | Agarwal D et al. | โ | 2022 | โ |
| Early pathways, biomarkers, and four distinct molecular subclasses of preeclampsia: The intersection of clinical, pathological, and high-dimensional biology studies. | Than NG et al. | โ | 2022 | โ |
| Elevated serum CEA is associated with liver metastasis and distinctive circulating tumor DNA alterations in patients with castration-resistant prostate cancer. | Bray AW et al. | โ | 2022 | โ |
| Emerging on-chip electrokinetic based technologies for purification of circulating cancer biomarkers towards liquid biopsy: A review. | Shi L et al. | โ | 2022 | โ |
| Emerging Technologies for Non-invasive Monitoring of Treatment Response to Immunotherapy for Brain Tumors. | Mathios D et al. | โ | 2022 | โ |
| Emerging Technologies for the Detection of Cancer Micrometastasis. | Mao X et al. | โ | 2022 | โ |
| Evolution of <i>RAS</i> Mutations in Cell-Free DNA of Patients with Tissue <i>RAS</i> Wild-Type Metastatic Colorectal Cancer Receiving First-Line Treatment: The PERSEIDA Study. | Valladares-Ayerbes M et al. | โ | 2022 | โ |
| Flexible Sensing Systems for Cancer Diagnostics. | Brooks AK et al. | โ | 2022 | โ |
| Future directions for precision oncology in prostate cancer. | Mizuno K et al. | โ | 2022 | โ |
| Genome-wide analysis of cell-Free DNA methylation profiling with MeDIP-seq identified potential biomarkers for colorectal cancer. | Zhang X et al. | โ | 2022 | โ |
| Genomic Instability in Cerebrospinal Fluid Cell-Free DNA Predicts Poor Prognosis in Solid Tumor Patients with Meningeal Metastasis. | Wang P et al. | โ | 2022 | โ |
| Imaging Biomarkers and Liquid Biopsy in Assessment of Cervical Cancer. | Ghani MA et al. | โ | 2022 | โ |
| Is Cell-Free DNA Testing in Pancreatic Ductal Adenocarcinoma Ready for Prime Time? | Sheel A et al. | โ | 2022 | โ |
| Isolation and Genomic Analysis of Single Circulating Tumor Cell Using Human Telomerase Reverse Transcriptase and Desmoglein-2. | Song JW et al. | โ | 2022 | โ |
| Label-Free Sensing with Metal Nanostructure-Based Surface-Enhanced Raman Spectroscopy for Cancer Diagnosis. | Constantinou M et al. | โ | 2022 | โ |
| Label-free surface enhanced Raman spectroscopy analysis of blood serum via coffee ring effect for accurate diagnosis of cancers. | Gao S et al. | โ | 2022 | โ |
| Large-Area Interfaces for Single-Molecule Label-free Bioelectronic Detection. | Macchia E et al. | โ | 2022 | โ |
| Liquid biopsies in primary and secondary bone cancers. | Ucci A et al. | โ | 2022 | โ |
| Liquid Biopsy and Circulating Biomarkers for the Diagnosis of Precancerous and Cancerous Oral Lesions. | Gattuso G et al. | โ | 2022 | โ |
| Liquid Biopsy and Its Emerging Role in Rheumatology. | ลwiecka M et al. | โ | 2022 | โ |
| Liquid biopsy: a step closer to transform diagnosis, prognosis and future of cancer treatments. | Lone SN et al. | โ | 2022 | โ |
| Liquid Biopsy-based Precision Therapy in Patients with Advanced Solid Tumors: A Real-world Experience from a Community-based Oncology Practice. | Choucair K et al. | โ | 2022 | โ |
| Liquid biopsy for the assessment of adrenal cancer heterogeneity: where do we stand? | Perge P et al. | โ | 2022 | โ |
| Liquid biopsy in lung cancer management. | Irofei Zamfir MA et al. | โ | 2022 | โ |
| Liquid Biopsy in Prostate Cancer Management-Current Challenges and Future Perspectives. | Crocetto F et al. | โ | 2022 | โ |
| Liquid biopsy: the value of different bodily fluids. | Santos V et al. | โ | 2022 | โ |
| Liquid biopsy using ascitic fluid and pleural effusion supernatants for genomic profiling in gastrointestinal and lung cancers. | Wu H et al. | โ | 2022 | โ |
| Longitudinal Monitoring of Circulating Tumor DNA to Predict Treatment Outcomes in Advanced Cancers. | Gouda MA et al. | โ | 2022 | โ |
| Lung cancer subtype diagnosis using weakly-paired multi-omics data. | Wang X et al. | โ | 2022 | โ |
| Machine Learning-Assisted Dual-Marker Detection in Serum Small Extracellular Vesicles for the Diagnosis and Prognosis Prediction of Non-Small Cell Lung Cancer. | Li W et al. | โ | 2022 | โ |
| Making the Rounds: Exploring the Role of Circulating Tumor DNA (ctDNA) in Non-Small Cell Lung Cancer. | Shields MD et al. | โ | 2022 | โ |
| Microfluidics-Based Urine Biopsy for Cancer Diagnosis: Recent Advances and Future Trends. | Wang Y et al. | โ | 2022 | โ |
| Microfluidics for detection of exosomes and microRNAs in cancer: State of the art. | Mousavi SM et al. | โ | 2022 | โ |
| Microfluidic Strategies for Extracellular Vesicle Isolation: Towards Clinical Applications. | Meggiolaro A et al. | โ | 2022 | โ |
| Molecular markers in cancer. | Ahmad E et al. | โ | 2022 | โ |
| Multiplex SuperSelective PCR Assays for the Detection and Quantitation of Rare Somatic Mutations in Liquid Biopsies. | Vargas DY et al. | โ | 2022 | โ |
| Non-coding RNAs as liquid biopsy biomarkers in cancer. | Toden S et al. | โ | 2022 | โ |
| Novel Diagnostic Biomarkers in Colorectal Cancer. | Zygulska AL et al. | โ | 2022 | โ |
| Pancreatic Tumorigenesis: Precursors, Genetic Risk Factors and Screening. | Badheeb M et al. | โ | 2022 | โ |
| Potential clinical utility of liquid biopsies in ovarian cancer. | Zhu JW et al. | โ | 2022 | โ |
| Pragmatic Expectancy on Microbiota and Non-Small Cell Lung Cancer: A Narrative Review. | Stella GM et al. | โ | 2022 | โ |
| Precision medicine in non-small cell lung cancer: Current applications and future directions. | Yang SR et al. | โ | 2022 | โ |
| Predicting cancer outcomes with radiomics and artificial intelligence in radiology. | Bera K et al. | โ | 2022 | โ |
| Preliminary Experience of Liquid Biopsy in Lung Cancer Compared to Conventional Assessment: Light and Shadows. | Montella M et al. | โ | 2022 | โ |
| Prognostic potential of circulating tumor DNA detection at different time periods in resectable non-small cell lung cancer: Evidence from a meta-analysis. | Wang B et al. | โ | 2022 | โ |
| Promising Blood-Based Biomarkers for Melanoma: Recent Progress of Liquid Biopsy and Its Future Perspectives. | Kanemaru H et al. | โ | 2022 | โ |
| Prostate Cancer-Associated miRNAs in Saliva: First Steps to an Easily Accessible and Reliable Screening Tool. | Luedemann C et al. | โ | 2022 | โ |
| Recent Advances in Exosomal miRNA Biosensing for Liquid Biopsy. | Lin B et al. | โ | 2022 | โ |
| Reporting on circulating tumor DNA monitoring in metastatic cancer-From clinical validity to clinical utility. | Brenner Thomsen C et al. | โ | 2022 | โ |
| Research progress and prospects of circulating tumor cells in hepatocellular carcinoma. | Li CC et al. | โ | 2022 | โ |
| Saliva Based Liquid Biopsies in Head and Neck Cancer: How Far Are We From the Clinic? | Patel A et al. | โ | 2022 | โ |
| Serum-Exosome-Derived miRNAs Serve as Promising Biomarkers for HCC Diagnosis. | Rui T et al. | โ | 2022 | โ |
| Single-Cell RNA Sequencing Uncovers Heterogeneous Circulating Tumor Cell Subsets in Breast Cancer. | Papadaki MA et al. | โ | 2022 | โ |
| Site-specific insertion of endonuclease recognition sites into amplicons to improve post-PCR analysis sensitivity of gene mutation. | Song L et al. | โ | 2022 | โ |
| Statistical biopsy: An emerging screening approach for early detection of cancers. | Hart GR et al. | โ | 2022 | โ |
| Synergistic enhanced rolling circle amplification based on mutS and radical polymerization for single-point mutation DNA detection. | Lee S et al. | โ | 2022 | โ |
| Systematic molecular analysis of the human secretome and membrane proteome in gastrointestinal adenocarcinomas. | Rehman AU et al. | โ | 2022 | โ |
| T790M and Acquired Resistance of Epidermal Growth Factor Receptor to Tyrosine Kinase Inhibitors in Patients with Lung Adenocarcinoma. | Mirtavoos-Mahyari H et al. | โ | 2022 | โ |
| Tailored point-of-care biosensors for liquid biopsy in the field of oncology. | Singh S et al. | โ | 2022 | โ |
| TCR repertoire and transcriptional signatures of circulating tumour-associated T cells facilitate effective non-invasive cancer detection. | Ji F et al. | โ | 2022 | โ |
| The evolving role of liquid biopsy in lung cancer. | Malapelle U et al. | โ | 2022 | โ |
| The potential of cell-free and exosomal microRNAs as biomarkers in liquid biopsy in patients with prostate cancer. | de Nรณbrega M et al. | โ | 2022 | โ |
| The Practicality of the Use of Liquid Biopsy in Early Diagnosis and Treatment Monitoring of Oral Cancer in Resource-Limited Settings. | Adeola HA et al. | โ | 2022 | โ |
| The RNA-binding protein HuR in human cancer: A friend or foe? | Wu X et al. | โ | 2022 | โ |
| The Role of Cell-Free DNA in Cancer Treatment Decision Making. | Telekes A et al. | โ | 2022 | โ |
| The scope of liquid biopsy in the clinical management of oral cancer. | Baby NT et al. | โ | 2022 | โ |
| The storm of NGS in NSCLC diagnostic-therapeutic pathway: How to sun the real clinical practice. | De Maglio G et al. | โ | 2022 | โ |
| The Utility of Repetitive Cell-Free DNA in Cancer Liquid Biopsies. | Gezer U et al. | โ | 2022 | โ |
| Transcriptional ITPR3 as potential targets and biomarkers for human pancreatic cancer. | Zheng W et al. | โ | 2022 | โ |
| Ultra Deep Sequencing of Circulating Cell-Free DNA as a Potential Tool for Hepatocellular Carcinoma Management. | Higuera M et al. | โ | 2022 | โ |
| Updated Neoadjuvant Treatment Landscape for Early Triple Negative Breast Cancer: Immunotherapy, Potential Predictive Biomarkers, and Novel Agents. | Garufi G et al. | โ | 2022 | โ |
| Utility of Cell-Free DNA Detection in Transplant Oncology. | Reddy T et al. | โ | 2022 | โ |
| Volatilome Analysis in Prostate Cancer by Electronic Nose: A Pilot Monocentric Study. | Filianoti A et al. | โ | 2022 | โ |
| Accurate detection of circulating tumor DNA using nanopore consensus sequencing. | Marcozzi A et al. | โ | 2021 | โ |
| A DNA methylation-based liquid biopsy for triple-negative breast cancer. | Cristall K et al. | โ | 2021 | โ |
| Advanced NSCLC Patients With EGFR T790M Harboring TP53 R273C or KRAS G12V Cannot Benefit From Osimertinib Based on a Clinical Multicentre Study by Tissue and Liquid Biopsy. | Fu Y et al. | โ | 2021 | โ |
| [Advances in Clinical Application of Liquid Biopsy in Non-small Cell Lung Cancer]. | Zhang M et al. | โ | 2021 | โ |
| Advances in the Detection of Pancreatic Cancer Through Liquid Biopsy. | Yan TB et al. | โ | 2021 | โ |
| Advances in the diagnosis, evaluation, and management of leptomeningeal disease. | Sener U et al. | โ | 2021 | โ |
| Advances in Tumor Sampling and Sequencing in Breast Cancer and their Application in Precision Diagnostics and Therapeutics. | Lee AC et al. | โ | 2021 | โ |
| A Nanoparticle-Conjugated Anti-TBK1 siRNA Induces Autophagy-Related Apoptosis and Enhances cGAS-STING Pathway in GBM Cells. | Xu S et al. | โ | 2021 | โ |
| A new sensitive and fast assay for the detection of EGFR mutations in liquid biopsies. | Jensen SG et al. | โ | 2021 | โ |
| A novel decision tree model based on chromosome imbalances in cell-free DNA and CA-125 in the differential diagnosis of ovarian cancer. | Zhang W et al. | โ | 2021 | โ |
| A pilot study of next generation sequencing-liquid biopsy on cell-free DNA as a novel non-invasive diagnostic tool for Klippel-Trenaunay syndrome. | Palmieri M et al. | โ | 2021 | โ |
| Apoptotic Tumor DNA Activated Nanomotor Chemotaxis. | Ye Y et al. | โ | 2021 | โ |
| Aptamer-Based Detection of Circulating Targets for Precision Medicine. | Wu L et al. | โ | 2021 | โ |
| A Real-World Application of Liquid Biopsy in Metastatic Colorectal Cancer: The Poseidon Study. | Procaccio L et al. | โ | 2021 | โ |
| A systematic review of modeling and simulation approaches in designing targeted treatment technologies for Leukemia Cancer in low and middle income countries. | Kiwumulo HF et al. | โ | 2021 | โ |
| Bead-Based Isolation of Circulating Tumor DNA from Pancreatic Cancer Patients Enables High Fidelity Next Generation Sequencing. | Balendran-Braun S et al. | โ | 2021 | โ |
| Biliary Strictures and Cholangiocarcinoma - Untangling a Diagnostic Conundrum. | Ney A et al. | โ | 2021 | โ |
| Bisulfite Amplicon Sequencing Can Detect Glia and Neuron Cell-Free DNA in Blood Plasma. | Chatterton Z et al. | โ | 2021 | โ |
| Breast Cancer Heterogeneity. | Fumagalli C et al. | โ | 2021 | โ |
| Cardiomyocyte-specific circulating cell-free methylated DNA in esophageal cancer patients treated with chemoradiation. | Roth SM et al. | โ | 2021 | โ |
| Cell-Free DNA Analysis by Whole-Exome Sequencing for Hepatocellular Carcinoma: A Pilot Study in Thailand. | Kunadirek P et al. | โ | 2021 | โ |
| Cell-free DNA from cerebrospinal fluid can be used to detect the <i>EGFR</i> mutation status of lung adenocarcinoma patients with central nervous system metastasis. | Liu Y et al. | โ | 2021 | โ |
| Cerebrospinal fluid liquid biopsy for detecting somatic mosaicism in brain. | Ye Z et al. | โ | 2021 | โ |
| Characteristics and Clinical Application of Extracellular Vesicle-Derived DNA. | Hur JY et al. | โ | 2021 | โ |
| Characterization of Plasma Cell-Free DNA Integrity Using Droplet-Based Digital PCR: Toward the Development of Circulating Tumor DNA-Dedicated Assays. | Poulet G et al. | โ | 2021 | โ |
| Circulating Tumor Cells: Technologies and Their Clinical Potential in Cancer Metastasis. | Xiao J et al. | โ | 2021 | โ |
| Circulating Tumor DNA Analyses Predict Disease Recurrence in Non-Muscle-Invasive Bladder Cancer. | Zhang J et al. | โ | 2021 | โ |
| Circulating tumor DNA in cancer: Predictive molecular pathology meets mathematics. | Malapelle U et al. | โ | 2021 | โ |
| Circulating tumor HPV DNA complements PET-CT in guiding management after radiotherapy in HPV-related squamous cell carcinoma of the head and neck. | Tanaka H et al. | โ | 2021 | โ |
| Circulating tumor-tissue modified HPV DNA analysis for molecular disease monitoring after chemoradiation for anal squamous cell carcinoma: a case report. | Liauw SL et al. | โ | 2021 | โ |
| Clinical Application Value of Circulating Cell-free DNA in Hepatocellular Carcinoma. | Zhang Y et al. | โ | 2021 | โ |
| Comparative analysis of nuclear and mitochondrial DNA from tissue and liquid biopsies of colorectal cancer patients. | Haupts A et al. | โ | 2021 | โ |
| Contemporary Molecular Analyses of Malignant Tumors for Precision Treatment and the Implication in Oral Squamous Cell Carcinoma. | Chang JYF et al. | โ | 2021 | โ |
| CRISPR/Cas-Based In Vitro Diagnostic Platforms for Cancer Biomarker Detection. | Gong S et al. | โ | 2021 | โ |
| Deconstructing Pancreatic Cancer Using Next Generation-Omic Technologies-From Discovery to Knowledge-Guided Platforms for Better Patient Management. | Schreyer D et al. | โ | 2021 | โ |
| Detecting Liquid Remnants of Solid Tumors: Circulating Tumor DNA Minimal Residual Disease. | Moding EJ et al. | โ | 2021 | โ |
| Detection of Leptomeningeal Disease Using Cell-Free DNA From Cerebrospinal Fluid. | White MD et al. | โ | 2021 | โ |
| Detection of Single Cancer Cells in Blood with Artificially Intelligent Nanoarray. | Einoch-Amor R et al. | โ | 2021 | โ |
| Development of an optimal protocol for molecular profiling of tumor cells in pleural effusions at single-cell level. | Nakamura IT et al. | โ | 2021 | โ |
| Diagnostic and Prognostic Characteristics of Circulating Free DNA Methylation Detected by the Electrochemical Method in Malignant Tumors. | Sun LY et al. | โ | 2021 | โ |
| Differential Glycosylation Levels in Saliva from Patients with Lung or Breast Cancer: A Preliminary Assessment for Early Diagnostic Purposes. | Ragusa A et al. | โ | 2021 | โ |
| DISMIR: Deep learning-based noninvasive cancer detection by integrating DNA sequence and methylation information of individual cell-free DNA reads. | Li J et al. | โ | 2021 | โ |
| Diving into the Pleural Fluid: Liquid Biopsy for Metastatic Malignant Pleural Effusions. | Sorolla MA et al. | โ | 2021 | โ |
| DNA Nanomachines for Identifying Cancer Biomarkers in Body Fluids and Cells. | Dong Z et al. | โ | 2021 | โ |
| Dynamic analysis of circulating tumor DNA to predict prognosis and monitor therapeutic response in metastatic relapsed cervical cancer. | Tian X et al. | โ | 2021 | โ |
| EGFR transcription in non-small-cell lung cancer tumours can be revealed in ctDNA by cell-free chromatin immunoprecipitation (cfChIP). | Mรฅnsson CT et al. | โ | 2021 | โ |
| Eight-year longitudinal study of whole blood gene expression profiles in individuals undergoing long-term medical follow-up. | Sakai Y et al. | โ | 2021 | โ |
| Enhanced lipid metabolism induces the sensitivity of dormant cancer cells to 5-aminolevulinic acid-based photodynamic therapy. | Nakayama T et al. | โ | 2021 | โ |
| Epithelial ovarian cancer and the use of circulating tumor DNA: A systematic review. | Thusgaard CF et al. | โ | 2021 | โ |
| Exosomal Non-Coding RNAs: Regulatory and Therapeutic Target of Hepatocellular Carcinoma. | Xia H et al. | โ | 2021 | โ |
| Exosome-Derived Long Non-Coding RNAs as Non-Invasive Biomarkers of Bladder Cancer. | Su Q et al. | โ | 2021 | โ |
| Exosomes and extracellular vesicles: Rethinking the essential values in cancer biology. | Yokoi A et al. | โ | 2021 | โ |
| Exosomes: a new perspective in EGFR-mutated lung cancer. | Jouida A et al. | โ | 2021 | โ |
| Expression and crucial role of long non-coding RNA FGD5-AS1 in human cancers. | Zhu L et al. | โ | 2021 | โ |
| Extracellular Vesicles: A Novel Tool Facilitating Personalized Medicine and Pharmacogenomics in Oncology. | Goriฤar K et al. | โ | 2021 | โ |
| Extracellular vesicles as a new hope for diagnosis and therapeutic intervention for hepatocellular carcinoma. | Nimitrungtawee N et al. | โ | 2021 | โ |
| Gene Mutations in Circulating Tumour DNA as a Diagnostic and Prognostic Marker in Head and Neck Cancer-A Systematic Review. | Hudeฤkovรก M et al. | โ | 2021 | โ |
| Guidelines for pre-analytical conditions for assessing the methylation of circulating cell-free DNA. | Kerachian MA et al. | โ | 2021 | โ |
| Harmful cytokines in cancer immunology and immunotherapy: biomarkers and targets? | Melero I et al. | โ | 2021 | โ |
| High concordance of mutation patterns in 10 common mutated genes between tumor tissue and cell-free DNA in metastatic colorectal cancer. | Lan YT et al. | โ | 2021 | โ |
| High sensitivity sanger sequencing detection of BRAF mutations in metastatic melanoma FFPE tissue specimens. | Cheng LY et al. | โ | 2021 | โ |
| High-throughput proteomics and AI for cancer biomarker discovery. | Xiao Q et al. | โ | 2021 | โ |
| Horizons in Veterinary Precision Oncology: Fundamentals of Cancer Genomics and Applications of Liquid Biopsy for the Detection, Characterization, and Management of Cancer in Dogs. | Chibuk J et al. | โ | 2021 | โ |
| Humoral Predictors of Malignancy in IPMN: A Review of the Literature. | Nista EC et al. | โ | 2021 | โ |
| Hydrogel-based hybridization chain reaction (HCR) for detection of urinary exosomal miRNAs as a diagnostic tool of prostate cancer. | Kim J et al. | โ | 2021 | โ |
| Identification and characterization of effusion tumor cells (ETCs) from remnant pleural effusion specimens. | Zhu Y et al. | โ | 2021 | โ |
| Identification of diagnostic and prognostic signatures derived from preoperative blood parameters for oral squamous cell carcinoma. | Wu X et al. | โ | 2021 | โ |
| Identification of piRNA Targets in Urinary Extracellular Vesicles for the Diagnosis of Prostate Cancer. | Peng Q et al. | โ | 2021 | โ |
| Identifying key questions in the ecology and evolution of cancer. | Dujon AM et al. | โ | 2021 | โ |
| Improving hexaminolevulinate enabled cancer cell detection in liquid biopsy immunosensors. | Chan KM et al. | โ | 2021 | โ |
| In Silico screening of circulating tumor DNA, circulating microRNAs, and long non-coding RNAs as diagnostic molecular biomarkers in ovarian cancer: A comprehensive meta-analysis. | Zhang L et al. | โ | 2021 | โ |
| Isolation and quantification of extracellular vesicle-encapsulated microRNA on an integrated microfluidic platform. | Sung CY et al. | โ | 2021 | โ |
| Liquid Biopsy: A Family of Possible Diagnostic Tools. | Michela B | โ | 2021 | โ |
| Liquid Biopsy as a Prognostic and Theranostic Tool for the Management of Pancreatic Ductal Adenocarcinoma. | Osei-Bordom DC et al. | โ | 2021 | โ |
| Liquid Biopsy as a Tool for the Characterisation and Early Detection of the Field Cancerization Effect in Patients with Oral Cavity Carcinoma. | Pรฉrez-Ruiz E et al. | โ | 2021 | โ |
| Liquid Biopsy Biomarkers in Urine: A Route towards Molecular Diagnosis and Personalized Medicine of Bladder Cancer. | Ferro M et al. | โ | 2021 | โ |
| Liquid Biopsy for Cancer Cachexia: Focus on Muscle-Derived microRNAs. | Belli R et al. | โ | 2021 | โ |
| Liquid Biopsy for Prognosis and Treatment in Metastatic Colorectal Cancer: Circulating Tumor Cells vs Circulating Tumor DNA. | Patelli G et al. | โ | 2021 | โ |
| Liquid Biopsy from Bile-Circulating Tumor DNA in Patients with Biliary Tract Cancer. | Han JY et al. | โ | 2021 | โ |
| Liquid biopsy from research to clinical practice: focus on non-small cell lung cancer. | Malapelle U et al. | โ | 2021 | โ |
| Liquid Biopsy in Breast Cancer: A Focused Review. | Tay TKY et al. | โ | 2021 | โ |
| Liquid Biopsy in Breast Cancer: Circulating Tumor Cells and Circulating Tumor DNA. | Yoo TK | โ | 2021 | โ |
| Liquid biopsy in cholangiocarcinoma: Current status and future perspectives. | Rompianesi G et al. | โ | 2021 | โ |
| Liquid biopsy with droplet digital PCR targeted to specific mutations in plasma cell-free tumor DNA can detect ovarian cancer recurrence earlier than CA125. | Minato T et al. | โ | 2021 | โ |
| Liver metastases. | Tsilimigras DI et al. | โ | 2021 | โ |
| Longitudinal analysis of cell-free mutated KRAS and CA 19-9 predicts survival following curative resection of pancreatic cancer. | Hussung S et al. | โ | 2021 | โ |
| Long Non-Coding RNAs in Epithelial-Mesenchymal Transition of Pancreatic Cancer. | Takahashi K et al. | โ | 2021 | โ |
| <i>BRAF</i> V600 Mutation Detection in Plasma Cell-Free DNA: NCCTG N0879 (Alliance). | Slostad JA et al. | โ | 2021 | โ |
| Machine Learning Protocols in Early Cancer Detection Based on Liquid Biopsy: A Survey. | Liu L et al. | โ | 2021 | โ |
| Metal-Organic Framework Hybrids Aid Metabolic Profiling for Colorectal Cancer. | Li X et al. | โ | 2021 | โ |
| MET somatic activating mutations are responsible for lymphovenous malformation and can be identified using cell-free DNA next generation sequencing liquid biopsy. | Palmieri M et al. | โ | 2021 | โ |
| Microfluidic-Based Exosome Analysis for Liquid Biopsy. | Lin B et al. | โ | 2021 | โ |
| Microfluidic Chip-Based Cancer Diagnosis and Prediction of Relapse by Detecting Circulating Tumor Cells and Circulating Cancer Stem Cells. | Cho HY et al. | โ | 2021 | โ |
| Monitoring HOTTIP levels on extracellular vesicles for predicting recurrence in surgical non-small cell lung cancer patients. | Han B et al. | โ | 2021 | โ |
| Multiple adsorption properties of aptamers on metal-organic frameworks for nucleic acid assay. | Xie X et al. | โ | 2021 | โ |
| Mutational landscape of plasma cell-free DNA identifies molecular features associated with therapeutic response in patients with colon cancer. A pilot study. | Cervena K et al. | โ | 2021 | โ |
| NAD<sup>+</sup> Metabolism Maintains Inducible PD-L1 Expression to Drive Tumor Immune Evasion. | Lv H et al. | โ | 2021 | โ |
| Nanomaterial Complexes Enriched With Natural Compounds Used in Cancer Therapies: A Perspective for Clinical Application. | Saavedra-Leos MZ et al. | โ | 2021 | โ |
| Non-invasive detection of biliary tract cancer by low-coverage whole genome sequencing from plasma cell-free DNA: A prospective cohort study. | Wang X et al. | โ | 2021 | โ |
| Noninvasive Detection of Hepatocellular Carcinoma with Circulating Tumor DNA Featuresย and ฮฑ-Fetoprotein. | Meng Z et al. | โ | 2021 | โ |
| Novel omics technology driving translational research in precision oncology. | Basu A et al. | โ | 2021 | โ |
| Optimization of Preanalytical Variables for cfDNA Processing and Detection of ctDNA in Archival Plasma Samples. | Nesic M et al. | โ | 2021 | โ |
| Peripheral Blood Genetic Biomarkers for the Early Diagnosis of Hepatocellular Carcinoma. | Song T et al. | โ | 2021 | โ |
| Plasma Cell-Free DNA Genotyping: From an Emerging Concept to a Standard-of-Care Tool in Metastatic Non-Small Cell Lung Cancer. | Gray J et al. | โ | 2021 | โ |
| Plasma KRAS mutations predict the early recurrence after surgical resection of pancreatic cancer. | Ako S et al. | โ | 2021 | โ |
| Postoperative circulating tumor DNA as markers of recurrence risk in stages II to III colorectal cancer. | Chen G et al. | โ | 2021 | โ |
| Postoperative Circulating Tumor DNA Can Predict High Risk Patients with Colorectal Cancer Based on Next-Generation Sequencing. | Lee CS et al. | โ | 2021 | โ |
| Precision Medicine for Colorectal Cancer with Liquid Biopsy and Immunotherapy. | Nagayama S et al. | โ | 2021 | โ |
| Prognosis of metastasis based on age and serum analytes after follow-up of non-metastatic lung cancer patients. | Balla MMS et al. | โ | 2021 | โ |
| Prognostic Significance of Blood-Based Multi-cancer Detection in Plasma Cell-Free DNA. | Chen X et al. | โ | 2021 | โ |
| Progress on the role of extrachromosomal DNA in tumor pathogenesis and evolution. | Xing J et al. | โ | 2021 | โ |
| Quest for Pan-Cancer Diagnosis/Prognosis Ends with HrC Test Measuring Oct4A in Peripheral Blood. | Tripathi V et al. | โ | 2021 | โ |
| Rapid and sensitive identification of pleural and peritoneal infections by droplet digital PCR. | Zhou F et al. | โ | 2021 | โ |
| Rapid kinetic fingerprinting of single nucleic acid molecules by a FRET-based dynamic nanosensor. | Khanna K et al. | โ | 2021 | โ |
| Rational Development of Liquid Biopsy Analysis in Renal Cell Carcinoma. | Glennon KI et al. | โ | 2021 | โ |
| Real-World Analysis of the <i>EGFR</i> Mutation Test in Tissue and Plasma Samples from Non-Small Cell Lung Cancer. | Lee H et al. | โ | 2021 | โ |
| Recent Advances in the Label-Free Characterization of Exosomes for Cancer Liquid Biopsy: From Scattering and Spectroscopy to Nanoindentation and Nanodevices. | Di Santo R et al. | โ | 2021 | โ |
| Recent developments in cancer research: Expectations for a new remedy. | Ando K et al. | โ | 2021 | โ |
| Reliability of BRAF mutation detection using plasma sample: A systematic review and meta-analysis | Ye P et al. | โ | 2021 | โ |
| Retrieval of vector integration sites from cell-free DNA. | Cesana D et al. | โ | 2021 | โ |
| Role of Long Non-Coding RNA LINC00641 in Cancer. | Han X et al. | โ | 2021 | โ |
| Sandwich-type detection of nucleic acids by bioorthogonal SERS probes. | Ota R et al. | โ | 2021 | โ |
| Sensitive Quantification of Cell-Free Tumor DNA for Early Detection of Recurrence in Colorectal Cancer. | Stasik S et al. | โ | 2021 | โ |
| Serum Extracellular Vesicle-Derived circHIPK3 and circSMARCA5 Are Two Novel Diagnostic Biomarkers for Glioblastoma Multiforme. | Stella M et al. | โ | 2021 | โ |
| Serum lnc34a is a potential prediction biomarker for bone metastasis in hepatocellular carcinoma patients. | Zhang L et al. | โ | 2021 | โ |
| Signatures Beyond Oncogenic Mutations in Cell-Free DNA Sequencing for Non-Invasive, Early Detection of Cancer. | De S | โ | 2021 | โ |
| Small extracellular vesicles in cancer. | Abhange K et al. | โ | 2021 | โ |
| Sputum-Based Tumor Fluid Biopsy: Isolation and High-Throughput Single-Cell Analysis of Exfoliated Tumor Cells for Lung Cancer Diagnosis. | Si H et al. | โ | 2021 | โ |
| Structural and mechanical characteristics of exosomes from osteosarcoma cells explored by 3D-atomic force microscopy. | Yurtsever A et al. | โ | 2021 | โ |
| The association between RAPSN methylation in peripheral blood and breast cancer in the Chinese population. | Lei S et al. | โ | 2021 | โ |
| The Clinical Application of Circulating Tumor Cells and DNAs as Prognostic and Predictive Biomarkers in Gastrointestinal Cancer. | Memarpour S et al. | โ | 2021 | โ |
| The Emerging Role of Liquid Biopsy in Gastric Cancer. | Lengyel CG et al. | โ | 2021 | โ |
| The Landscape of Actionable Genomic Alterations by Next-Generation Sequencing in Tumor Tissue Versus Circulating Tumor DNA in Chinese Patients With Non-Small Cell Lung Cancer. | Cai J et al. | โ | 2021 | โ |
| The Liquid Biopsy for Lung Cancer: State of the Art, Limitations and Future Developments. | Di Capua D et al. | โ | 2021 | โ |
| The prognostic value of longitudinal circulating tumor DNA profiling during osimertinib treatment. | Ma S et al. | โ | 2021 | โ |
| The Role of Exosomes in the Pathophysiology of Chronic Rhinosinusitis. | Mueller SK | โ | 2021 | โ |
| The role of molecular heterogeneity targeting resistance mechanisms to lung cancer therapies. | Attili I et al. | โ | 2021 | โ |
| Tumor-derived exosomal microRNA-106b-5p activates EMT-cancer cell and M2-subtype TAM interaction to facilitate CRC metastasis. | Yang C et al. | โ | 2021 | โ |
| Two-Step Competitive Hybridization Assay: A Method for Analyzing Cancer-Related microRNA Embedded in Extracellular Vesicles. | Saha S et al. | โ | 2021 | โ |
| Ultrasensitive circulating tumor DNA analysis enables precision medicine: experimental workflow considerations. | Andersson D et al. | โ | 2021 | โ |
| Using cfRNA as a tool to evaluate clinical treatment outcomes in patients with metastatic lung cancers and other tumors. | Raez LE et al. | โ | 2021 | โ |
| Voxelated three-dimensional miniature magnetic soft machines via multimaterial heterogeneous assembly. | Zhang J et al. | โ | 2021 | โ |
| What Is Known about Theragnostic Strategies in Colorectal Cancer. | Parisi A et al. | โ | 2021 | โ |
| Whole genome sequencing of low input circulating cell-free DNA obtained from normal human subjects. | Foley JF et al. | โ | 2021 | โ |
| 10-Plex Digital Polymerase Chain Reaction with Four-Color Melting Curve Analysis for Simultaneous <i>KRAS</i> and <i>BRAF</i> Genotyping. | Nakagawa T et al. | โ | 2020 | โ |
| 5hmC-MIQuant: Ultrasensitive Quantitative Detection of 5-Hydroxymethylcytosine in Low-Input Cell-Free DNA Samples. | Yuan F et al. | โ | 2020 | โ |
| 5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic and predictive biomarkers for coronary artery disease. | Dong C et al. | โ | 2020 | โ |
| A biocomposite-based rapid sampling assay for circulating cell-free DNA in liquid biopsy samples from human cancers. | Koo B et al. | โ | 2020 | โ |
| A circulating tumor cell-based digital assay for the detection of EGFR T790M mutation in advanced non-small cell lung cancer. | Wang J et al. | โ | 2020 | โ |
| A Distinctive microRNA (miRNA) Signature in the Blood of Colorectal Cancer (CRC) Patients at Surgery. | Gasparello J et al. | โ | 2020 | โ |
| Advances in the Detection Technologies and Clinical Applications of Circulating Tumor DNA in Metastatic Breast Cancer. | Liao H et al. | โ | 2020 | โ |
| A Multianalyte Panel Consisting of Extracellular Vesicle miRNAs and mRNAs, cfDNA, and CA19-9 Shows Utility for Diagnosis and Staging of Pancreatic Ductal Adenocarcinoma. | Yang Z et al. | โ | 2020 | โ |
| A multicenter real-world study of tumor-derived DNA from pleural effusion supernatant in genomic profiling of advanced lung cancer. | Jin S et al. | โ | 2020 | โ |
| Analytical performance evaluation of a commercial next generation sequencing liquid biopsy platform using plasma ctDNA, reference standards, and synthetic serial dilution samples derived from normal plasma. | Verma S et al. | โ | 2020 | โ |
| A novel device to capture circulating tumor cells: Quantification and molecular analysis in lung cancer patients. | Cheng Y et al. | โ | 2020 | โ |
| A Simple and Fast Assay Based on Carboxyfluorescein-Loaded Liposome for Quantitative DNA Detection. | Sforzi J et al. | โ | 2020 | โ |
| A Targeted Gene Panel for Circulating Tumor DNA Sequencing in Neuroblastoma. | Cimmino F et al. | โ | 2020 | โ |
| Biobanking in Molecular Biomarker Research for the Early Detection of Cancer. | Lommen K et al. | โ | 2020 | โ |
| Bioconjugated gold nanoparticles as an efficient colorimetric sensor for cancer diagnostics. | Akshaya K et al. | โ | 2020 | โ |
| Biomolecular Sensing at the Interface between Chiral Metasurfaces and Hyperbolic Metamaterials. | Palermo G et al. | โ | 2020 | โ |
| Blood-based <i>RAS</i> mutation testing: concordance with tissue-based <i>RAS</i> testing and mutational changes on progression. | Germetaki T et al. | โ | 2020 | โ |
| Cell-free DNA for genomic profiling and minimal residual disease monitoring in Myeloma- are we there yet? | Thakral D et al. | โ | 2020 | โ |
| Cell-free DNA next-generation sequencing liquid biopsy as a new revolutionary approach for arteriovenous malformation. | Palmieri M et al. | โ | 2020 | โ |
| Cell-free DNA promotes malignant transformation in non-tumor cells. | Souza AG et al. | โ | 2020 | โ |
| Circulating cell-free DNA variables as marker of ovarian cancer patients: A pilot study. | Stamenkovic S et al. | โ | 2020 | โ |
| Circulating miR34a levels as a potential biomarker in the follow-up of Ewing sarcoma. | Sciandra M et al. | โ | 2020 | โ |
| Circulating Tumor Cells as a Biomarker to Assist Molecular Diagnosis for Early Stage Non-Small Cell Lung Cancer. | He Y et al. | โ | 2020 | โ |
| Circulating Tumor DNA as a Novel Biomarker Optimizing Chemotherapy for Colorectal Cancer. | Osumi H et al. | โ | 2020 | โ |
| Circulating tumor DNA clearance predicts prognosis across treatment regimen in a large real-world longitudinally monitored advanced non-small cell lung cancer cohort. | Song Y et al. | โ | 2020 | โ |
| Circulating Tumor DNA in Biliary Tract Cancer: Current Evidence and Future Perspectives. | Rizzo A et al. | โ | 2020 | โ |
| Circulating tumor DNA: Where are we now? A mini review of the literature. | Galarza Fortuna GM et al. | โ | 2020 | โ |
| Circulating tumor-specific DNA: a stony road to clinical utility. | Thomsen CB et al. | โ | 2020 | โ |
| Circulating tumour-derived KRAS mutations in pancreatic cancer cases are predominantly carried by very short fragments of cell-free DNA. | Zvereva M et al. | โ | 2020 | โ |
| Clinical Applications of Cerebrospinal Fluid Circulating Tumor DNA as a Liquid Biopsy for Central Nervous System Tumors. | Yan W et al. | โ | 2020 | โ |
| Clinical Features of Patients with an Epidermal Growth Factor Receptor T790M Mutation Detected in Circulating Tumor DNA. | Ikushima H et al. | โ | 2020 | โ |
| Colorectal Adenomas-Genetics and Searching for New Molecular Screening Biomarkers. | Siskova A et al. | โ | 2020 | โ |
| Comparison of EML4-ALK fusion gene positive rate in different detection methods and samples of non-small cell lung cancer. | Lu S et al. | โ | 2020 | โ |
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| Concordance of Genomic Alterations between Circulating Tumor DNA and Matched Tumor Tissue in Chinese Patients with Breast Cancer. | Xu B et al. | โ | 2020 | โ |
| Concordance of Genomic Alterations by Next-Generation Sequencing in Tumor Tissue versus Cell-Free DNA in Stage I-IV Non-Small Cell Lung Cancer. | Jiang J et al. | โ | 2020 | โ |
| CRISPR-dCas9 powered impedimetric biosensor for label-free detection of circulating tumor DNAs. | Uygun ZO et al. | โ | 2020 | โ |
| Critical Review: digital resolution biomolecular sensing for diagnostics and life science research. | Huang Q et al. | โ | 2020 | โ |
| ctDNA as a cancer biomarker: A broad overview. | Pessoa LS et al. | โ | 2020 | โ |
| Current and future applications of liquid biopsy in nonsmall cell lung cancer from early to advanced stages. | Guibert N et al. | โ | 2020 | โ |
| Current Status of Circulating Tumor DNA Liquid Biopsy in Pancreatic Cancer. | Grunvald MW et al. | โ | 2020 | โ |
| Detection of epidermal growth factor receptor mutations in exhaled breath condensate using droplet digital polymerase chain reaction. | Nishii K et al. | โ | 2020 | โ |
| Detection of <i>EGFR</i> Mutations in Plasma Cell-Free Tumor DNA of TKI-Treated Advanced-NSCLC Patients by Three Methodologies: Scorpion-ARMS, PNAClamp, and Digital PCR. | Siggillino A et al. | โ | 2020 | โ |
| Developments in predictive biomarkers for hepatocellular carcinoma therapy. | Casadei-Gardini A et al. | โ | 2020 | โ |
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| Direct kinetic fingerprinting and digital counting of single protein molecules. | Chatterjee T et al. | โ | 2020 | โ |
| Direct plasmonic detection of circulating RAS mutated DNA in colorectal cancer patients. | D'Agata R et al. | โ | 2020 | โ |
| Dissecting Molecular Features of Gliomas: Genetic Loci and Validated Biomarkers. | Arcella A et al. | โ | 2020 | โ |
| DNA methylation-driven EMT is a common mechanism of resistance to various therapeutic agents in cancer. | Galle E et al. | โ | 2020 | โ |
| Donor-specific cell-free DNA as a biomarker in liver transplantation: A review. | McClure T et al. | โ | 2020 | โ |
| Establishment and application of a method of next generation sequencing of 285 genes in lung cancer based on Ion-Proton platform. | Chen Y et al. | โ | 2020 | โ |
| Evaluating the diagnostic accuracy of a ctDNA methylation classifier for incidental lung nodules: protocol for a prospective, observational, and multicenter clinical trial of 10,560 cases. | Liang W et al. | โ | 2020 | โ |
| Evaluation of a Liquid Biopsy Protocol using Ultra-Deep Massive Parallel Sequencing for Detecting and Quantifying Circulation Tumor DNA in Colorectal Cancer Patients. | Nguyen HT et al. | โ | 2020 | โ |
| Facile fluorescent aptasensor using aggregation-induced emission luminogens for exosomal proteins profiling towards liquid biopsy. | Li B et al. | โ | 2020 | โ |
| Feasibility of methylated ctDNA detection in plasma samples of oropharyngeal squamous cell carcinoma patients. | de Jesus LM et al. | โ | 2020 | โ |
| Ferritin Light Chain (FTL) competes with long noncoding RNA Linc00467 for miR-133b binding site to regulate chemoresistance and metastasis of colorectal cancer. | Li Z et al. | โ | 2020 | โ |
| Finding new cancer epigenetic and genetic biomarkers from cell-free DNA by combining SALP-seq and machine learning. | Liu S et al. | โ | 2020 | โ |
| Frequency of S492R mutations in the epidermal growth factor receptor: analysis of plasma DNA from patients with metastatic colorectal cancer treated with panitumumab or cetuximab monotherapy. | Price T et al. | โ | 2020 | โ |
| Future directions and management of liquid biopsy in non-small cell lung cancer. | Cossu AM et al. | โ | 2020 | โ |
| Genetic alterations in B cell lymphoma subtypes as potential biomarkers for noninvasive diagnosis, prognosis, therapy, and disease monitoring. | Esmeray E et al. | โ | 2020 | โ |
| Genetic biomarkers to guide poly(ADP-ribose) polymeraseย inhibitor precision treatment of prostate cancer. | Varnai R et al. | โ | 2020 | โ |
| Genetic Markers in Lung Cancer Diagnosis: A Review. | Wadowska K et al. | โ | 2020 | โ |
| Hepatocellular carcinoma: old friends and new tricks. | Kim E et al. | โ | 2020 | โ |
| High-metastatic cancer cells derived exosomal miR92a-3p promotes epithelial-mesenchymal transition and metastasis of low-metastatic cancer cells by regulating PTEN/Akt pathway in hepatocellular carcinoma. | Yang B et al. | โ | 2020 | โ |
| Hybrid Nanoplasmonic Porous Biomaterial Scaffold for Liquid Biopsy Diagnostics Using Extracellular Vesicles. | Rojalin T et al. | โ | 2020 | โ |
| Identification of Human Secretome and Membrane Proteome-Based Cancer Biomarkers Utilizing Bioinformatics. | Rehman AU et al. | โ | 2020 | โ |
| Identifying circulating miRNA biomarkers for early diagnosis and monitoring of lung cancer. | Zhang YH et al. | โ | 2020 | โ |
| Induction of apoptosis increases sensitivity to detect cancer mutations in plasma. | Marques JF et al. | โ | 2020 | โ |
| Integrated epigenetic biomarkers in circulating cell-free DNA as a robust classifier for pancreatic cancer. | Cao F et al. | โ | 2020 | โ |
| Isolation and mutational assessment of pancreatic cancer extracellular vesicles using a microfluidic platform. | Kamyabi N et al. | โ | 2020 | โ |
| Is tissue still the issue in detecting molecular alterations in lung cancer? | Liam CK et al. | โ | 2020 | โ |
| Latency and interval therapy affect the evolution in metastatic colorectal cancer. | Nikbakht H et al. | โ | 2020 | โ |
| Levels of Extracellular Vesicles in Pulmonary and Peripheral Blood Correlate with Stages of Lung Cancer Patients. | Choi BH et al. | โ | 2020 | โ |
| Leveraging locus-specific epigenetic heterogeneity to improve the performance of blood-based DNA methylation biomarkers. | Miller BF et al. | โ | 2020 | โ |
| Liquid Biopsy: A Biomarker-Driven Tool towards Precision Oncology. | Yee NS | โ | 2020 | โ |
| Liquid biopsy and tumor heterogeneity in metastatic solid tumors: the potentiality of blood samples. | Russano M et al. | โ | 2020 | โ |
| [Liquid biopsy-aย possible key player in immuno-oncology]. | Wallesch M et al. | โ | 2020 | โ |
| Liquid Biopsy as a Tool Exploring in Real-Time Both Genomic Perturbation and Resistance to EGFR Antagonists in Colorectal Cancer. | Internรฒ V et al. | โ | 2020 | โ |
| Liquid biopsy in ovarian cancer: Catching the silent killer before it strikes. | Feeney L et al. | โ | 2020 | โ |
| Liquid Biopsy is Instrumental for 3PM Dimensional Solutions in Cancer Management. | Liskova A et al. | โ | 2020 | โ |
| Liquid Biopsy: The Unique Test for Chasing the Genetics of Solid Tumors. | Aghamir SMK et al. | โ | 2020 | โ |
| Liquid biopsy using extracellular vesicle-derived DNA in lung adenocarcinoma. | Kim IA et al. | โ | 2020 | โ |
| Low expression of Talin1 is associated with advanced pathological features in colorectal cancer patients. | Vafaei S et al. | โ | 2020 | โ |
| MASS SPECTROMETRY-BASED PERSONALIZED DRUG THERAPY. | Cui JJ et al. | โ | 2020 | โ |
| Metabolite profiling of human blood by surface-enhanced Raman spectroscopy for surgery assessment and tumor screening in breast cancer. | Lin D et al. | โ | 2020 | โ |
| Modular affinity-labeling of the cytosine demethylation base elements in DNA. | Wang F et al. | โ | 2020 | โ |
| Molecular signature comprising 11 platelet-genes enables accurate blood-based diagnosis of NSCLC. | Goswami C et al. | โ | 2020 | โ |
| Multiplex-invasive reaction-assisted qPCR for quantitatively detecting the abundance of EGFR exon 19 deletions in cfDNA. | Tang Y et al. | โ | 2020 | โ |
| Multiprobe Assay for Clinical <i>SEPT9</i> Methylation Based on the Carbon Dot-Modified Liquid-Exfoliated Graphene Field Effect Transistor with a Potential to Present a Methylation Panorama. | Dong D et al. | โ | 2020 | โ |
| Nanotechnology Strategies for the Analysis of Circulating Tumor DNA: A Review. | Chen X et al. | โ | 2020 | โ |
| New Insights into Diffuse Large B-Cell Lymphoma Pathobiology. | Solimando AG et al. | โ | 2020 | โ |
| Next Generation Sequencing-Based Profiling of Cell Free DNA in Patients with Advanced Non-Small Cell Lung Cancer: Advantages and Pitfalls. | Esposito Abate R et al. | โ | 2020 | โ |
| Noninvasive characterization of Alzheimer's disease by circulating, cell-free messenger RNA next-generation sequencing. | Toden S et al. | โ | 2020 | โ |
| Non-invasive detection of EGFR mutations by cell-free loop-mediated isothermal amplification (CF-LAMP). | Arjuna S et al. | โ | 2020 | โ |
| Optimal treatment strategy for metastatic melanoma patients harboring <i>BRAF-V600</i> mutations. | Giunta EF et al. | โ | 2020 | โ |
| Plasma circulating tumor DNA assessment reveals <i>KMT2D</i> as a potential poor prognostic factor in extranodal NK/T-cell lymphoma. | Li Q et al. | โ | 2020 | โ |
| Plasma Level of Circular RNA hsa_circ_0000190 Correlates with Tumor Progression and Poor Treatment Response in Advanced Lung Cancers. | Luo YH et al. | โ | 2020 | โ |
| Plasma Predictive Features in Treating EGFR-Mutated Non-Small Cell Lung Cancer. | Steendam CMJ et al. | โ | 2020 | โ |
| Potential theranostics of circulating tumor cells and tumor-derived exosomes application in colorectal cancer. | Vafaei S et al. | โ | 2020 | โ |
| Preanalytical variables that affect the outcome of cell-free DNA measurements. | Ungerer V et al. | โ | 2020 | โ |
| Precision cell-free DNA extraction for liquid biopsy by integrated microfluidics. | Lee H et al. | โ | 2020 | โ |
| Precision medicine for gastrointestinal cancer: Recent progress and future perspective. | Matsuoka T et al. | โ | 2020 | โ |
| Precision Medicine for NSCLC in the Era of Immunotherapy: New Biomarkers to Select the Most Suitable Treatment or the Most Suitable Patient. | Rossi G et al. | โ | 2020 | โ |
| Predictive value of exosomes and their cargo in drug response/resistance of breast cancer patients. | Schwarzenbach H et al. | โ | 2020 | โ |
| Prognostic value of circulating tumor DNA in pancreatic cancer: a systematic review and meta-analysis. | Fang Z et al. | โ | 2020 | โ |
| Prognostic Value of Serum NPY Hypermethylation in Neoadjuvant Chemoradiotherapy for Rectal Cancer: Secondary Analysis of a Randomized Trial. | Appelt AL et al. | โ | 2020 | โ |
| Recent Advances in Droplet Microfluidics. | Ding Y et al. | โ | 2020 | โ |
| Salivary biomarkers for cancer diagnosis: a meta-analysis. | Rapado-Gonzรกlez ร et al. | โ | 2020 | โ |
| Sample collection for laboratory-based study of the nasal airway and sinuses: a research compendium. | Massey CJ et al. | โ | 2020 | โ |
| Sensor-Integrated Microfluidic Approaches for Liquid Biopsies Applications in Early Detection of Cancer. | Sierra J et al. | โ | 2020 | โ |
| Simultaneous Isolation of Circulating Nucleic Acids and EV-Associated Protein Biomarkers From Unprocessed Plasma Using an AC Electrokinetics-Based Platform. | Hinestrosa JP et al. | โ | 2020 | โ |
| Single-molecule analysis of nucleic acid biomarkers - A review. | Gilboa T et al. | โ | 2020 | โ |
| Single-molecule detection of cancer mutations using a novel PCR-LDR-qPCR assay. | Ruiz C et al. | โ | 2020 | โ |
| SinoDuplex: An Improved Duplex Sequencing Approach to Detect Low-frequency Variants in Plasma cfDNA Samples. | Ren Y et al. | โ | 2020 | โ |
| Somatic copy number aberrations in metastatic patients: The promise of liquid biopsies. | Baldacchino S et al. | โ | 2020 | โ |
| Strand displacement-triggered G-quadruplex/rolling circle amplification strategy for the ultra-sensitive electrochemical sensing of exosomal microRNAs. | Tang X et al. | โ | 2020 | โ |
| Strategic Combinations to Prevent and Overcome Resistance to Targeted Therapies in Oncology. | Gumusay O et al. | โ | 2020 | โ |
| Targeted Sequencing of Genomic Repeat Regions Detects Circulating Cell-freeย Echinococcus DNA. | Wan Z et al. | โ | 2020 | โ |
| The Current State of Molecular Testing in the BRAF-Mutated Melanoma Landscape. | Vanni I et al. | โ | 2020 | โ |
| The Liquid Biopsy in the Management of Colorectal Cancer: An Overview. | Vacante M et al. | โ | 2020 | โ |
| The Translational Potential of Electrochemical DNA-Based Liquid Biopsy. | Miranda-Castro R et al. | โ | 2020 | โ |
| Toward Systems Pathology for PTEN Diagnostics. | Haddadi N et al. | โ | 2020 | โ |
| Tumor-Educated Platelet RNA for the Detection and (Pseudo)progression Monitoring of Glioblastoma. | Sol N et al. | โ | 2020 | โ |
| Ultra-Deep Massive Parallel Sequencing of Plasma Cell-Free DNA Enables Large-Scale Profiling of Driver Mutations in Vietnamese Patients With Advanced Non-Small Cell Lung Cancer. | Tran LS et al. | โ | 2020 | โ |
| Ultrasensitive melanoma biomarker detection using a microchip SERS immunoassay with anisotropic Au-Ag alloy nanoboxes. | Kumar AR et al. | โ | 2020 | โ |
| Ultrasensitive Multiplex Detection of Single Nucleotide Polymorphisms Based on Short-Chain Hybridization Combined with Online Preconcentration of Capillary Electrophoresis. | Zhou QY et al. | โ | 2020 | โ |
| Understanding EGFR heterogeneity in lung cancer. | Passaro A et al. | โ | 2020 | โ |
| Using gold nanoparticles to detect single-nucleotide polymorphisms: toward liquid biopsy. | Iglesias MS et al. | โ | 2020 | โ |
| Utility of circulating tumor cells and DNA in the management of advanced colorectal cancer. | Pan X et al. | โ | 2020 | โ |
| Utility of urinary ctDNA to monitoring minimal residual disease in early breast cancer patients. | Guan G et al. | โ | 2020 | โ |
| What animals can teach us about evolution, the human genome, and human disease. | Lindblad-Toh K | โ | 2020 | โ |
| Adjunctive Use of Circulating Tumor DNA Testing in Detecting Pancreas Cancer Recurrence. | Soyano AE et al. | โ | 2019 | โ |
| A guide to nucleic acid detection by single-molecule kinetic fingerprinting. | Johnson-Buck A et al. | โ | 2019 | โ |
| An Acoustic Droplet-Induced Enzyme Responsive Platform for the Capture and On-Demand Release of Single Circulating Tumor Cells. | Wei X et al. | โ | 2019 | โ |
| Analysis of circulating non-coding RNAs in a non-invasive and cost-effective manner. | Wang YM et al. | โ | 2019 | โ |
| A new primer construction technique that effectively increases amplification of rare mutant templates in samples. | Huang JK et al. | โ | 2019 | โ |
| An Optimized Workflow to Evaluate Estrogen Receptor Gene Mutations in Small Amounts of Cell-Free DNA. | Vitale SR et al. | โ | 2019 | โ |
| A novel ratiometric SERS biosensor with one Raman probe for ultrasensitive microRNA detection based on DNA hydrogel amplification. | He Y et al. | โ | 2019 | โ |
| An ultrasensitive test for profiling circulating tumor DNA using integrated comprehensive droplet digital detection. | Ou CY et al. | โ | 2019 | โ |
| A Phase II Trial of Osimertinib in the Second-Line Treatment of Non-small Cell Lung Cancer with the EGFR T790M Mutation, Detected from Circulating Tumor DNA: LiquidLung-O-Cohort 2. | Park CK et al. | โ | 2019 | โ |
| A plasma metabolite panel as biomarkers for early primary breast cancer detection. | Yuan B et al. | โ | 2019 | โ |
| Application of plasma circulating cell-free DNA detection to the molecular diagnosis of hepatocellular carcinoma. | He G et al. | โ | 2019 | โ |
| Applying circulating tumor DNA methylation in the diagnosis of lung cancer. | Li L et al. | โ | 2019 | โ |
| A Snapshot of The Tumor Microenvironment in Colorectal Cancer: The Liquid Biopsy. | Herrera M et al. | โ | 2019 | โ |
| Association Between Liquid Biopsy and Prognosis of Gastric Cancer Patients: A Systematic Review and Meta-Analysis. | Gao Y et al. | โ | 2019 | โ |
| A Systematic Investigation of the Malignant Functions and Diagnostic Potential of the Cancer Secretome. | Robinson JL et al. | โ | 2019 | โ |
| Bioinformatics Analysis for Circulating Cell-Free DNA in Cancer. | Huang CC et al. | โ | 2019 | โ |
| Bio-Inspired NanoVilli Chips for Enhanced Capture of Tumor-Derived Extracellular Vesicles: Toward Non-Invasive Detection of Gene Alterations in Non-Small Cell Lung Cancer. | Dong J et al. | โ | 2019 | โ |
| Blood Collection and Cell-Free DNA Isolation Methods Influence the Sensitivity of Liquid Biopsy Analysis for Colorectal Cancer Detection. | Bartรกk BK et al. | โ | 2019 | โ |
| Cancer immunoediting and resistance to T cell-based immunotherapy. | O'Donnell JS et al. | โ | 2019 | โ |
| Can liquid biopsy-guided <i>EGFR</i>-targeted therapy be a surrogate for the tissue-based standard approach? | Oh IJ | โ | 2019 | โ |
| Cell-free circulating tumor DNA in patients with high-grade glioma as diagnostic biomarker - A guide to future directive. | Ahmed KI et al. | โ | 2019 | โ |
| Cell-free DNA as a biomarker in diffuse large B-cell lymphoma: A systematic review. | Arzuaga-Mendez J et al. | โ | 2019 | โ |
| Cell-Free DNA Methylation Profiling Analysis-Technologies and Bioinformatics. | Huang J et al. | โ | 2019 | โ |
| Circulating free tumor DNA in non-small cell lung cancer (NSCLC): clinical application and future perspectives. | Herbreteau G et al. | โ | 2019 | โ |
| Circulating tumor cells in precision oncology: clinical applications in liquid biopsy and 3D organoid model. | Yang C et al. | โ | 2019 | โ |
| Circulating Tumor Cells in Renal Cell Carcinoma: Recent Findings and Future Challenges. | Santoni M et al. | โ | 2019 | โ |
| Circulating Tumor Cells: State-of-the-art Update on Technologies and Clinical Applications. | Yap K et al. | โ | 2019 | โ |
| Circulating tumor DNA analyses predict progressive disease and indicate trastuzumab-resistant mechanism in advanced gastric cancer. | Wang Y et al. | โ | 2019 | โ |
| Circulating tumor DNA detection: A potential tool for colorectal cancer management. | Li H et al. | โ | 2019 | โ |
| Circulating tumor DNA dynamics using patient-customized assays are associated with outcome in neoadjuvantly treated breast cancer. | Butler TM et al. | โ | 2019 | โ |
| Circulating Tumour Cells in Predictive Molecular Pathology: Focus on Drug-Sensitive Assays and 3D Culture. | Pallante P et al. | โ | 2019 | โ |
| Clinical Application of Next-Generation Sequencing as A Liquid Biopsy Technique in Advanced Colorectal Cancer: A Trick or A Treat? | Kastrisiou M et al. | โ | 2019 | โ |
| Clinical applications of liquid biopsies for early lung cancer detection. | Zheng H et al. | โ | 2019 | โ |
| Clinical feasibility of NGS liquid biopsy analysis in NSCLC patients. | Papadopoulou E et al. | โ | 2019 | โ |
| Clinical relevance of circulating molecules in cancer: focus on gastrointestinal stromal tumors. | Ravegnini G et al. | โ | 2019 | โ |
| Clinical relevance of circulating tumor DNA assessed through deep sequencing in patients with metastatic colorectal cancer. | Osumi H et al. | โ | 2019 | โ |
| Clinical utility of circulating tumor DNA for colorectal cancer. | Osumi H et al. | โ | 2019 | โ |
| Common molecular markers between circulating tumor cells and blood exosomes in colorectal cancer: a systematic and analytical review. | Vafaei S et al. | โ | 2019 | โ |
| Comparison of Roche Cell-Free DNA collection Tubes <sup><i>ยฎ</i></sup> to Streck Cell-Free DNA BCT <sup><i>ยฎ</i></sup> s for sample stability using healthy volunteers. | Parackal S et al. | โ | 2019 | โ |
| Comparison of the Clinical Sensitivity of the Idylla Platform and the OncoBEAM RAS CRC Assay for KRAS Mutation Detection in Liquid Biopsy Samples. | Vivancos A et al. | โ | 2019 | โ |
| Completing the genetic spectrum influencing coronary artery disease: from germline to somatic variation. | Patel AP et al. | โ | 2019 | โ |
| Comprehensive analysis of genomic alterations detected by next-generation sequencing-based tissue and circulating tumor DNA assays in Chinese patients with non-small cell lung cancer. | Yang H et al. | โ | 2019 | โ |
| Comprehensive Evaluation of the Factors Affecting Plasma Circulating Cell-Free DNA Levels and Their Application in Diagnosing Nonsmall Cell Lung Cancer. | Chen Z et al. | โ | 2019 | โ |
| Covalent chemistry on nanostructured substrates enables noninvasive quantification of gene rearrangements in circulating tumor cells. | Dong J et al. | โ | 2019 | โ |
| Current and Future Trends on Diagnosis and Prognosis of Glioblastoma: From Molecular Biology to Proteomics. | Silantyev AS et al. | โ | 2019 | โ |
| Decoding genetic and epigenetic information embedded in cell free DNA with adapted SALP-seq. | Wu J et al. | โ | 2019 | โ |
| Detection of AR-V7 in Liquid Biopsies of Castrate Resistant Prostate Cancer Patients: A Comparison of AR-V7 Analysis in Circulating Tumor Cells, Circulating Tumor RNA and Exosomes. | Nimir M et al. | โ | 2019 | โ |
| Detection of Circulating Tumor DNA with a Single-Molecule Sequencing Analysis Validated for Targeted and Immunotherapy Selection. | Atkins A et al. | โ | 2019 | โ |
| Detection of KRAS mutations in plasma cell-free DNA of colorectal cancer patients and comparison with cancer panel data for tissue samples of the same cancers. | Min S et al. | โ | 2019 | โ |
| Detection of microRNA using a polydopamine mediated bimetallic SERS substrate and aย re-circulated enzymatic amplification system. | Jiang N et al. | โ | 2019 | โ |
| Disease prediction by cell-free DNA methylation. | Feng H et al. | โ | 2019 | โ |
| Drainage of Tumor-Derived DNA into Sentinel Lymph Nodes in Breast Cancer Patients. | Miyamura Y et al. | โ | 2019 | โ |
| Early change in circulating tumor DNA as a potential predictor of response to chemotherapy in patients with metastatic colorectal cancer. | Osumi H et al. | โ | 2019 | โ |
| Early detection and monitoring of cancer in liquid biopsy: advances and challenges. | Xue VW et al. | โ | 2019 | โ |
| Emerging Nanotechnologies for Liquid Biopsy: The Detection of Circulating Tumor Cells and Extracellular Vesicles. | Li W et al. | โ | 2019 | โ |
| Epigenetic Biomarkers in Cell-Free DNA and Applications in Liquid Biopsy. | Gai W et al. | โ | 2019 | โ |
| Essential updates 2017/2018: Recent topics in the treatment and research of gastric cancer in Japan. | Komatsu S et al. | โ | 2019 | โ |
| Evaluation of serum exosomal LncRNA-based biomarker panel for diagnosis and recurrence prediction of bladder cancer. | Zhang S et al. | โ | 2019 | โ |
| eVIDENCE: a practical variant filtering for low-frequency variants detection in cell-free DNA. | Mizuno K et al. | โ | 2019 | โ |
| Evolving Clinical Utility of Liquid Biopsy in Gastrointestinal Cancers. | Jacobson RA et al. | โ | 2019 | โ |
| Exosomes: Isolation, Analysis, and Applications in Cancer Detection and Therapy. | Bu H et al. | โ | 2019 | โ |
| Exosome-specific tumor diagnosis via biomedical analysis of exosome-containing microRNA biomarkers. | Fan Z et al. | โ | 2019 | โ |
| Failed immune responses across multiple pathologies share pan-tumor and circulating lymphocytic targets. | Monette A et al. | โ | 2019 | โ |
| FGB and FGG derived from plasma exosomes as potential biomarkers to distinguish benign from malignant pulmonary nodules. | Kuang M et al. | โ | 2019 | โ |
| Genome-Wide Plasma Cell-Free DNA Methylation Profiling Identifies Potential Biomarkers for Lung Cancer. | Xu W et al. | โ | 2019 | โ |
| Genomic analysis of pancreatic juice DNA assesses malignant risk of intraductal papillary mucinous neoplasm of pancreas. | Mateos RN et al. | โ | 2019 | โ |
| Genomic profile of urine has high diagnostic sensitivity compared to cytology in non-invasive urothelial bladder cancer. | Hirotsu Y et al. | โ | 2019 | โ |
| Glycans as Biomarkers in Prostate Cancer. | Scott E et al. | โ | 2019 | โ |
| Graphene Oxide-Based Biosensors for Liquid Biopsies in Cancer Diagnosis. | Chen SL et al. | โ | 2019 | โ |
| Harnessing the Microbiome for Pancreatic Cancer Immunotherapy. | Vitiello GA et al. | โ | 2019 | โ |
| Highlighting the uniqueness in dielectrophoretic enrichment of circulating tumor cells. | S Iliescu F et al. | โ | 2019 | โ |
| HIV Detection via a Carbon Nanotube RNA Sensor. | Harvey JD et al. | โ | 2019 | โ |
| How liquid biopsies can change clinical practice in oncology. | Siravegna G et al. | โ | 2019 | โ |
| Hydrogel-Coated Microneedle Arrays for Minimally Invasive Sampling and Sensing of Specific Circulating Nucleic Acids from Skin Interstitial Fluid. | Al Sulaiman D et al. | โ | 2019 | โ |
| Identification of non-invasive biomarkers for chronic atrophic gastritis from serum exosomal microRNAs. | Liu H et al. | โ | 2019 | โ |
| Immunosignature Screening for Multiple Cancer Subtypes Based on Expression Rule. | Chen L et al. | โ | 2019 | โ |
| Investigation of Preanalytical Variables Impacting Pathogen Cell-Free DNA in Blood and Urine. | Murugesan K et al. | โ | 2019 | โ |
| IQN path ASBL report from the first European cfDNA consensus meeting: expert opinion on the minimal requirements for clinical ctDNA testing. | Deans ZC et al. | โ | 2019 | โ |
| Isolation and Retrieval of Extracellular Vesicles for Liquid Biopsy of Malignant Ground-Glass Opacity. | Mao W et al. | โ | 2019 | โ |
| Label-free liquid biopsy based on blood circulating DNA detection using SERS-based nanotechnology for nasopharyngeal cancer screening. | Lin D et al. | โ | 2019 | โ |
| Large-scale Circulating microRNA Profiling for the Liquid Biopsy of Prostate Cancer. | Urabe F et al. | โ | 2019 | โ |
| Leukobiopsy - A Possible New Liquid Biopsy Platform for Detecting Oncogenic Mutations. | Chennakrishnaiah S et al. | โ | 2019 | โ |
| Life and death of circulating cell-free DNA. | Kustanovich A et al. | โ | 2019 | โ |
| Liquid biopsies in myeloid malignancies. | Abdulmawjood B et al. | โ | 2019 | โ |
| Liquid biopsies in pancreatic cancer. | Kamyabi N et al. | โ | 2019 | โ |
| Liquid Biopsy and Lung Cancer. | Pisapia P et al. | โ | 2019 | โ |
| Liquid Biopsy as a Minimally Invasive Source of Thyroid Cancer Genetic and Epigenetic Alterations. | Khatami F et al. | โ | 2019 | โ |
| Liquid Biopsy as a Tool for Differentiation of Leiomyomas and Sarcomas of Corpus Uteri. | Dvorskรก D et al. | โ | 2019 | โ |
| Liquid Biopsy as Surrogate for Tissue for Molecular Profiling in Pancreatic Cancer: A Meta-Analysis Towards Precision Medicine. | Luchini C et al. | โ | 2019 | โ |
| Liquid Biopsy beyond Circulating Tumor Cells and Cell-Free DNA. | Junqueira-Neto S et al. | โ | 2019 | โ |
| Liquid biopsy challenge and hope in colorectal cancer. | Burz C et al. | โ | 2019 | โ |
| Liquid biopsy for detection of EGFR T790M mutation in nonsmall cell lung cancer: An experience of proficiency testing in Taiwan. | Ho HL et al. | โ | 2019 | โ |
| [Liquid biopsy in colorectal cancer : An overview of ctDNA analysis in tumour diagnostics]. | Haupts A et al. | โ | 2019 | โ |
| Liquid biopsy in combination with solid-state electrochemical sensors and nucleic acid amplification. | Tabata M et al. | โ | 2019 | โ |
| Liquid biopsy in head and neck squamous cell carcinoma: Prognostic significance of circulating tumor cells and circulating tumor DNA. A systematic review. | Lauritano D et al. | โ | 2019 | โ |
| Liquid biopsy in hepatocellular carcinoma: circulating tumor cells and circulating tumor DNA. | Ye Q et al. | โ | 2019 | โ |
| Liquid Biopsy in Solid Malignancy. | Scarlotta M et al. | โ | 2019 | โ |
| [Liquid biopsy in tumor diagnostics : Applications, perspectives, and limitations of the "cancer liquidome"]. | Lehmann U et al. | โ | 2019 | โ |
| Liquid biopsy: miRNA as a potential biomarker in oral cancer. | Mazumder S et al. | โ | 2019 | โ |
| Low-pass Whole-genome Sequencing of Circulating Cell-free DNA Demonstrates Dynamic Changes in Genomic Copy Number in a Squamous Lung Cancer Clinical Cohort. | Chen X et al. | โ | 2019 | โ |
| Macrofluidic Device for Preparative Concentration Based on Epitachophoresis. | Foret F et al. | โ | 2019 | โ |
| Maximum allele frequency observed in plasma: A potential indicator of liquid biopsy sensitivity. | Tang Y et al. | โ | 2019 | โ |
| Media Coverage of the Benefits and Harms of Testing the Healthy: a protocol for a descriptive study. | O'Keeffe M et al. | โ | 2019 | โ |
| MicroRNA-204-5p: A novel candidate urinary biomarker of Xp11.2 translocation renal cell carcinoma. | Kurahashi R et al. | โ | 2019 | โ |
| MicroRNA-338-5p reverses chemoresistance and inhibits invasion of esophageal squamous cell carcinoma cells by targeting Id-1. | Han L et al. | โ | 2019 | โ |
| Mitochondrial protein enriched extracellular vesicles discovered in human melanoma tissues can be detected in patient plasma. | Jang SC et al. | โ | 2019 | โ |
| Molecular and clinical analysis of Chinese patients with anaplastic lymphoma kinase (ALK)-rearranged non-small cell lung cancer. | Zhou X et al. | โ | 2019 | โ |
| Molecular subtyping of colorectal cancer: Recent progress, new challenges and emerging opportunities. | Wang W et al. | โ | 2019 | โ |
| Monitoring circulating tumor DNA by analyzing personalized cancer-specific rearrangements to detect recurrence in gastric cancer. | Kim YW et al. | โ | 2019 | โ |
| Multilayer microfluidic array for highly efficient sample loading and digital melt analysis of DNA methylation. | O'Keefe CM et al. | โ | 2019 | โ |
| Nanotechnology in Radiation Oncology. | Sun B et al. | โ | 2019 | โ |
| Next-generation sequencing in liquid biopsy: cancer screening and early detection. | Chen M et al. | โ | 2019 | โ |
| Noninvasive exosomal proteomic biosignatures, including cystatin SN, peroxiredoxin-5, and glycoprotein VI, accurately predict chronic rhinosinusitis with nasal polyps. | Mueller SK et al. | โ | 2019 | โ |
| Noninvasive molecular diagnosis of craniopharyngioma with MRI-based radiomics approach. | Chen X et al. | โ | 2019 | โ |
| Optimisation of robust singleplex and multiplex droplet digital PCR assays for high confidence mutation detection in circulating tumour DNA. | Rowlands V et al. | โ | 2019 | โ |
| Origami-paper-based device for microvesicle/exosome preconcentration and isolation. | Kim H et al. | โ | 2019 | โ |
| Parallel serial assessment of somatic mutation and methylation profile from circulating tumor DNA predicts treatment response and impending disease progression in osimertinib-treated lung adenocarcinoma patients. | Xia S et al. | โ | 2019 | โ |
| Perspectives on the expansion of human precision oncology and genomic approaches to sea turtle fibropapillomatosis. | Duffy DJ et al. | โ | 2019 | โ |
| Plasma cell-free DNA integrity: a potential biomarker to monitor the response of breast cancer to neoadjuvant chemotherapy. | Wang W et al. | โ | 2019 | โ |
| Plasma Cell-Free DNA Testing of Patients With EGFR Mutant Non-Small-Cell Lung Cancer: Droplet Digital PCR Versus Next-Generation Sequencing Compared With Tissue-Based Results. | Steendam CMJ et al. | โ | 2019 | โ |
| Plasma free DNA: Evaluation of temperature-associated storage effects observed for Roche Cell-Free DNA collection tubes. | Enko D et al. | โ | 2019 | โ |
| Potential Utility of Liquid Biopsy as a Diagnostic and Prognostic Tool for the Assessment of Solid Tumors: Implications in the Precision Oncology. | Mathai RA et al. | โ | 2019 | โ |
| Precision Medicine Tools to Guide Therapy and Monitor Response to Treatment in a HER-2+ Gastric Cancer Patient: Case Report. | Aguilar-Mahecha A et al. | โ | 2019 | โ |
| Prevalence of T790M mutation among TKI-therapy resistant Lebanese lung cancer patients based on liquid biopsy analysis: a first report from a major tertiary care center. | Assi H et al. | โ | 2019 | โ |
| Proteomic Analysis of Extracellular Vesicles for Cancer Diagnostics. | Wu AY et al. | โ | 2019 | โ |
| Questionnaire survey on patient awareness of invasive rebiopsy in advanced non-small cell lung cancer. | Fukui T et al. | โ | 2019 | โ |
| Recent advances in microfluidic methods in cancer liquid biopsy. | Iliescu FS et al. | โ | 2019 | โ |
| Role of liver biopsy in hepatocellular carcinoma. | Di Tommaso L et al. | โ | 2019 | โ |
| Roles of Extracellular HSPs as Biomarkers in Immune Surveillance and Immune Evasion. | Taha EA et al. | โ | 2019 | โ |
| Self-Seeding Microwells to Isolate and Assess the Viability of Single Circulating Tumor Cells. | Andree KC et al. | โ | 2019 | โ |
| Sensing of circulating cancer biomarkers with metal nanoparticles. | Pallares RM et al. | โ | 2019 | โ |
| SiNPle: Fast and Sensitive Variant Calling for Deep Sequencing Data. | Ferretti L et al. | โ | 2019 | โ |
| Surface Plasmon Resonance for Biomarker Detection: Advances in Non-invasive Cancer Diagnosis. | Bellassai N et al. | โ | 2019 | โ |
| Targeting EZH2 for glioma therapy with a novel nanoparticle-siRNA complex. | Wang X et al. | โ | 2019 | โ |
| Technical and Regulatory Considerations for Taking Liquid Biopsy to the Clinic: Validation of the JAX PlasmaMonitor<sup>TM</sup> Assay. | Sisson BA et al. | โ | 2019 | โ |
| The diagnostic accuracy of circulating free DNA for the detection of KRAS mutation status in colorectal cancer: A meta-analysis. | Xie W et al. | โ | 2019 | โ |
| The emerging role of cell-free DNA as a molecular marker for cancer management. | Bronkhorst AJ et al. | โ | 2019 | โ |
| The evolving role of receptors as predictive biomarkers for metastatic breast cancer. | Martรญnez-Pรฉrez C et al. | โ | 2019 | โ |
| The interplay of circulating tumor DNA and chromatin modification, therapeutic resistance, and metastasis. | Zhang L et al. | โ | 2019 | โ |
| Thermal Liquid Biopsy (TLB): A Predictive Score Derived from Serum Thermograms as a Clinical Tool for Screening Lung Cancer Patients. | Rodrigo A et al. | โ | 2019 | โ |
| The road map of cancer precision medicine with the innovation of advanced cancer detection technology and personalized immunotherapy. | Low SK et al. | โ | 2019 | โ |
| The use of cell free DNA in the diagnosis of HCC. | Banini BA et al. | โ | 2019 | โ |
| TOP-GAN: Stain-free cancer cell classification using deep learning with a small training set. | Rubin M et al. | โ | 2019 | โ |
| Toward Personalized Cancer Treatment: From Diagnostics to Therapy Monitoring in Miniaturized Electrohydrodynamic Systems. | Khondakar KR et al. | โ | 2019 | โ |
| Towards Circulating-Tumor DNA-Based Precision Medicine. | Hironaka-Mitsuhashi A et al. | โ | 2019 | โ |
| Treatment According to Molecular Profiling in Relapsed/Refractory Cancer Patients: A Review Focusing on Latest Profiling Studies. | Zimmer K et al. | โ | 2019 | โ |
| Tumor-derived extracellular vesicles: reliable tools for Cancer diagnosis and clinical applications. | Rahbarghazi R et al. | โ | 2019 | โ |
| Tumor-specific genetic aberrations in cell-free DNA of gastroesophageal cancer patients. | Koldby KM et al. | โ | 2019 | โ |
| Ultra-deep massively parallel sequencing with unique molecular identifier tagging achieves comparable performance to droplet digital PCR for detection and quantification of circulating tumor DNA from lung cancer patients. | Tran LS et al. | โ | 2019 | โ |
| Ultrasensitive Detection of Circulating Tumor DNA in Lymphoma via Targeted Hybridization Capture and Deep Sequencing of Barcoded Libraries. | Alcaide M et al. | โ | 2019 | โ |
| Unique genomic profiles obtained from cerebrospinal fluid cell-free DNA of non-small cell lung cancer patients with leptomeningeal metastases. | Ying S et al. | โ | 2019 | โ |
| Urine-Based Liquid Biopsy for Nonurological Cancers. | Jain S et al. | โ | 2019 | โ |
| Validation of Cell-Free DNA Collection Tubes for Determination of EGFR Mutation Status in Liquid Biopsy from NSCLC Patients. | Sesรฉ M et al. | โ | 2019 | โ |
| Why the Gold Standard Approach by Mammography Demands Extension by Multiomics? Application of Liquid Biopsy miRNA Profiles to Breast Cancer Disease Management. | Zubor P et al. | โ | 2019 | โ |
| A comparison of QuantStudioโข 3D Digital PCR and ARMS-PCR for measuring plasma EGFR T790M mutations of NSCLC patients. | Feng Q et al. | โ | 2018 | โ |
| A dual biomarker detection platform for quantitating circulating tumor DNA (ctDNA). | Cai C et al. | โ | 2018 | โ |
| Advancements in microfluidic technologies for isolation and early detection of circulating cancer-related biomarkers. | Rana A et al. | โ | 2018 | โ |
| A fast sample processing strategy for large-scale profiling of human urine phosphoproteome by mass spectrometry. | Zhao X et al. | โ | 2018 | โ |
| An update on liquid biopsy analysis for diagnostic and monitoring applications in non-small cell lung cancer. | Mayo-de-Las-Casas C et al. | โ | 2018 | โ |
| A pilot study of ultra-deep targeted sequencing of plasma DNA identifies driver mutations in hepatocellular carcinoma. | Labgaa I et al. | โ | 2018 | โ |
| Application and optimization of minimally invasive cell-free DNA techniques in oncogenomics. | Kumar M et al. | โ | 2018 | โ |
| Application of liquid biopsy in bone and soft tissue sarcomas: Present and future. | Li X et al. | โ | 2018 | โ |
| A single digital droplet PCR assay to detect multiple <i>KIT</i> exon 11 mutations in tumor and plasma from patients with gastrointestinal stromal tumors. | Boonstra PA et al. | โ | 2018 | โ |
| Association between clinical characteristics and the diagnostic accuracy of circulating single-molecule amplification and resequencing technology on detection epidermal growth factor receptor mutation status in plasma of lung adenocarcinoma. | Shi C et al. | โ | 2018 | โ |
| A versatile label-free electrochemical biosensor for circulating tumor DNA based on dual enzyme assisted multiple amplification strategy. | Wang HF et al. | โ | 2018 | โ |
| Benefit of everolimus as a monotherapy for a refractory breast cancer patient bearing multiple genetic mutations in the PI3K/AKT/mTOR signaling pathway. | Shi Y et al. | โ | 2018 | โ |
| Biotinylated amplicon sequencing: A method for preserving DNA samples of limited quantity. | Cravero K et al. | โ | 2018 | โ |
| Blood-Based Cancer Biomarkers in Liquid Biopsy: A Promising Non-Invasive Alternative to Tissue Biopsy. | Marrugo-Ramรญrez J et al. | โ | 2018 | โ |
| Case report: Whole exome sequencing of circulating cell-free tumor DNA in a follicular thyroid carcinoma patient with lung and bone metastases. | Song J et al. | โ | 2018 | โ |
| Cell-Cycle and DNA-Damage Response Pathway Is Involved in Leptomeningeal Metastasis of Non-Small Cell Lung Cancer. | Fan Y et al. | โ | 2018 | โ |
| Cell-Free eccDNAs: A New Type of Nucleic Acid Component for Liquid Biopsy? | Zhu J et al. | โ | 2018 | โ |
| Centrifugation-free extraction of circulating nucleic acids using immiscible liquid under vacuum pressure. | Lee H et al. | โ | 2018 | โ |
| Characterization and diagnostic application of genomic <i>NPM-ALK</i> fusion sequences in anaplastic large-cell lymphoma. | Krumbholz M et al. | โ | 2018 | โ |
| Characterization of Factors Affecting the Detection Limit of EGFR p.T790M in Circulating Tumor DNA. | Fahoum I et al. | โ | 2018 | โ |
| Circulating Cell-Free DNA and Colorectal Cancer: A Systematic Review. | Vymetalkova V et al. | โ | 2018 | โ |
| Circulating cell-free DNA of methylated insulin-like growth factor-binding protein 7 predicts a poor prognosis in hepatitis B virus-associated hepatocellular carcinoma after hepatectomy. | Li F et al. | โ | 2018 | โ |
| Circulating cell-free plasma tumour DNA shows a higher incidence of <i>EGFR</i> mutations in patients with extrathoracic disease progression. | Seki Y et al. | โ | 2018 | โ |
| Circulating HER-2 mRNA in the peripheral blood as a potential diagnostic and prognostic biomarker in females with breast cancer. | Wu Y et al. | โ | 2018 | โ |
| Circulating tumoral DNA: Preanalytical validation and quality control in a diagnostic laboratory. | Nikolaev S et al. | โ | 2018 | โ |
| Circulating tumor cells: Screening and monitoring of oral cancers. | Chowdhury R et al. | โ | 2018 | โ |
| Circulating tumor DNA analysis in patients with EGFR mutant lung cancer. | Nanjo S et al. | โ | 2018 | โ |
| Circulating tumor DNA as a liquid biopsy in plasma cell dyscrasias. | Gerber B et al. | โ | 2018 | โ |
| Circulating tumor DNA (ctDNA) in the era of personalized cancer therapy. | Khatami F et al. | โ | 2018 | โ |
| Circulating Tumor DNA for Early Cancer Detection. | Fiala C et al. | โ | 2018 | โ |
| Circulating tumor DNA in blood: Future genomic biomarkers for cancer detection. | Sumbal S et al. | โ | 2018 | โ |
| Circulating tumor DNA in patients with colorectal adenomas: assessment of detectability and genetic heterogeneity. | Myint NNM et al. | โ | 2018 | โ |
| Clinical significance of BRAF<sup>V600E</sup> mutation in circulating tumor DNA in Chinese patients with melanoma. | Tang H et al. | โ | 2018 | โ |
| Colorectal cancer early methylation alterations affect the crosstalk between cell and surrounding environment, tracing a biomarker signature specific for this tumor. | Fadda A et al. | โ | 2018 | โ |
| Combination Approach for Detecting Different Types of Alterations in Circulating Tumor DNA in Leiomyosarcoma. | Przybyl J et al. | โ | 2018 | โ |
| Correlation between circulating cell-free PIK3CA tumor DNA levels and treatment response in patients with PIK3CA-mutated metastatic breast cancer. | Kodahl AR et al. | โ | 2018 | โ |
| dCas9-mediated Nanoelectrokinetic Direct Detection of Target Gene for Liquid Biopsy. | Lee H et al. | โ | 2018 | โ |
| Decoding colorectal cancer epigenomics. | El Bairi K et al. | โ | 2018 | โ |
| Detection of circulating tumor DNA in patients with osteosarcoma. | Barris DM et al. | โ | 2018 | โ |
| Detection of EGFR mutations in plasma circulating tumour DNA as a selection criterion for first-line gefitinib treatment in patients with advanced lung adenocarcinoma (BENEFIT): a phase 2, single-arm, multicentre clinical trial. | Wang Z et al. | โ | 2018 | โ |
| Detection of EGFR Variants in Plasma: A Multilaboratory Comparison of a Real-Time PCR EGFR Mutation Test in Europe. | Keppens C et al. | โ | 2018 | โ |
| Detection of epidermal growth factor receptor mutations in circulating tumor DNA: reviewing BENEFIT clinical trial. | Malapelle U et al. | โ | 2018 | โ |
| Developing Ultrasensitive Library-Aliquot-Based Droplet Digital PCR for Detecting T790M in Plasma-Circulating Tumor DNA of Non-small-Cell-Lung-Cancer Patients. | Yang K et al. | โ | 2018 | โ |
| Diagnostic value of peripheral blood immune profiling in colorectal cancer. | Choi J et al. | โ | 2018 | โ |
| Discovery of methylated circulating DNA biomarkers for comprehensive non-invasive monitoring of treatment response in metastatic colorectal cancer. | Barault L et al. | โ | 2018 | โ |
| Droplet-based digital PCR and next generation sequencing for monitoring circulating tumor DNA: a cancer diagnostic perspective. | Postel M et al. | โ | 2018 | โ |
| Droplet microfluidics for high-sensitivity and high-throughput detection and screening of disease biomarkers. | Kaushik AM et al. | โ | 2018 | โ |
| Exosome-Based Detection of <i>EGFR</i> T790M in Plasma from Non-Small Cell Lung Cancer Patients. | Castellanos-Rizaldos E et al. | โ | 2018 | โ |
| Exosome function in aerodigestive mucosa. | Mueller SK et al. | โ | 2018 | โ |
| Exosomes and chronic rhinosinusitis. | Mueller SK | โ | 2018 | โ |
| Extending Circulating Tumor DNA Analysis to Ultralow Abundance Mutations: Techniques and Challenges. | Rodda AE et al. | โ | 2018 | โ |
| Facile profiling of molecular heterogeneity by microfluidic digital melt. | O'Keefe CM et al. | โ | 2018 | โ |
| Filtration based assessment of CTCs and CellSearchยฎ based assessment are both powerful predictors of prognosis for metastatic breast cancer patients. | Huebner H et al. | โ | 2018 | โ |
| Genomic alterations in plasma DNA from patients with metastasized prostate cancer receiving abiraterone or enzalutamide. | Belic J et al. | โ | 2018 | โ |
| Genomic Profiling and Metabolic Homeostasis in Primary Liver Cancers. | Gingold JA et al. | โ | 2018 | โ |
| HER2 copy number of circulating tumour DNA functions as a biomarker to predict and monitor trastuzumab efficacy in advanced gastric cancer. | Wang H et al. | โ | 2018 | โ |
| High-density single cell mRNA sequencing to characterize circulating tumor cells in hepatocellular carcinoma. | D'Avola D et al. | โ | 2018 | โ |
| Highly Efficient Exosome Isolation and Protein Analysis by an Integrated Nanomaterial-Based Platform. | Fang X et al. | โ | 2018 | โ |
| Highly multiplexed proteomic analysis reveals significant tissue and exosomal coagulation pathway derangement in chronic rhinosinusitis with nasal polyps. | Mueller SK et al. | โ | 2018 | โ |
| High Serum Level of Soluble Programmed Death Ligand 1 is Associated With a Poor Prognosis in Hodgkin Lymphoma. | Guo X et al. | โ | 2018 | โ |
| HOTAIR contributes to cell proliferation and metastasis of cervical cancer via targetting <i>miR-23b</i>/MAPK1 axis. | Li Q et al. | โ | 2018 | โ |
| Incorporating blood-based liquid biopsy information into cancer staging: time for a TNMB system? | Yang M et al. | โ | 2018 | โ |
| In situ, amplification-free double-stranded mutation detection at 60 copies/ml with thousand-fold wild type in urine. | Kirimli C et al. | โ | 2018 | โ |
| Integration of biomimicry and nanotechnology for significantly improved detection of circulating tumor cells (CTCs). | Myung JH et al. | โ | 2018 | โ |
| International pilot external quality assessment scheme for analysis and reporting of circulating tumour DNA. | Keppens C et al. | โ | 2018 | โ |
| Investigation of appropriate pre-analytical procedure for circulating free DNA from liquid biopsy. | Sato A et al. | โ | 2018 | โ |
| In vitro diagnosis of DNA methylation biomarkers with digital PCR in breast tumors. | Cui X et al. | โ | 2018 | โ |
| Latest development of liquid biopsy. | Cheung AH et al. | โ | 2018 | โ |
| Liquid biopsies for hepatocellular carcinoma. | Su YH et al. | โ | 2018 | โ |
| Liquid biopsies for management of pancreatic cancer. | Samandari M et al. | โ | 2018 | โ |
| Liquid biopsy: a new source of candidate biomarkers in amyotrophic lateral sclerosis. | Mendioroz M et al. | โ | 2018 | โ |
| Liquid Biopsy Biomarkers in Bladder Cancer: A Current Need for Patient Diagnosis and Monitoring. | Lodewijk I et al. | โ | 2018 | โ |
| Liquid biopsy for early stage lung cancer. | Liang W et al. | โ | 2018 | โ |
| Liquid biopsy in pancreatic cancer: the beginning of a new era. | Yadav DK et al. | โ | 2018 | โ |
| Liquid Biopsy in Tumor Genetic Diagnosis. | Jung A et al. | โ | 2018 | โ |
| Liquid biopsy of cancer: a multimodal diagnostic tool in clinical oncology. | Palmirotta R et al. | โ | 2018 | โ |
| LncRNAs and <i>EGFRvIII</i> sequestered in TEPs enable blood-based NSCLC diagnosis. | Luo CL et al. | โ | 2018 | โ |
| Machine learning to detect signatures of disease in liquid biopsies - a user's guide. | Ko J et al. | โ | 2018 | โ |
| Mapping of genomic EGFRvIII deletions in glioblastoma: insight into rearrangement mechanisms and biomarker development. | Koga T et al. | โ | 2018 | โ |
| Mechanisms of Resistance to Target Therapies in Non-small Cell Lung Cancer. | Facchinetti F et al. | โ | 2018 | โ |
| Microfluidic approaches for cell-based molecular diagnosis. | Lee DJ et al. | โ | 2018 | โ |
| Modularized Extracellular Vesicles: The Dawn of Prospective Personalized and Precision Medicine. | Tao SC et al. | โ | 2018 | โ |
| Molecular assessment of circulating exosomes toward liquid biopsy diagnosis of Ewing sarcoma family of tumors. | Zhang P et al. | โ | 2018 | โ |
| Monitoring circulating tumor DNA revealed dynamic changes in <i>KRAS</i> status in patients with metastatic colorectal cancer. | Takayama Y et al. | โ | 2018 | โ |
| Multiplex real-time PCR assay combined with rolling circle amplification (MPRP) using universal primers for non-invasive detection of tumor-related mutations. | Gong J et al. | โ | 2018 | โ |
| Mutational monitoring of EGFR T790M in cfDNA for clinical outcome prediction in EGFR-mutant lung adenocarcinoma. | Su KY et al. | โ | 2018 | โ |
| Mutation Detection in Tumor-Derived Cell Free DNA Anticipates Progression in a Patient With Metastatic Colorectal Cancer. | de Figueiredo Barros BD et al. | โ | 2018 | โ |
| Noninvasive Biomarkers of Colorectal Cancer: Role in Diagnosis and Personalised Treatment Perspectives. | Pellino G et al. | โ | 2018 | โ |
| Noninvasive Glioblastoma Testing: Multimodal Approach to Monitoring and Predicting Treatment Response. | Verduin M et al. | โ | 2018 | โ |
| Novel molecular insights and new therapeutic strategies in osteosarcoma. | Otoukesh B et al. | โ | 2018 | โ |
| Pancreatic Cancer Diagnosis and Management: Has the Time Come to Prick the Bubble? | Moutinho-Ribeiro P et al. | โ | 2018 | โ |
| Paper-Based Strips for the Electrochemical Detection of Single and Double Stranded DNA. | Cinti S et al. | โ | 2018 | โ |
| Parallel profiling of cancer cells and proteins using a graphene oxide functionalized ac-EHD SERS immunoassay. | Reza KK et al. | โ | 2018 | โ |
| Personalized genomic analysis based on circulating tumor cells of extra-skeletal Ewing sarcoma of the uterus: A case report of a 16-year-old Korean female. | Lee SY et al. | โ | 2018 | โ |
| Potential Management of Circulating Tumor DNA as a Biomarker in Triple-Negative Breast Cancer. | Shang M et al. | โ | 2018 | โ |
| Potential of quantitative SEPT9 and SHOX2 methylation in plasmatic circulating cell-free DNA as auxiliary staging parameter in colorectal cancer: a prospective observational cohort study. | Bergheim J et al. | โ | 2018 | โ |
| Practical issues of biomarker-assisted targeted therapy in precision medicine and immuno-oncology era. | Lee DH | โ | 2018 | โ |
| Pre- and Postoperative Chemotherapy in Localized Extremity Soft Tissue Sarcoma: A European Organization for Research and Treatment of Cancer Expert Survey. | Rothermundt C et al. | โ | 2018 | โ |
| Predicting cancer cell invasion by single-cell physical phenotyping. | Nyberg KD et al. | โ | 2018 | โ |
| Principles of DNA methylation and their implications for biology and medicine. | Dor Y et al. | โ | 2018 | โ |
| Progress and challenges of sequencing and analyzing circulating tumor cells. | Zhu Z et al. | โ | 2018 | โ |
| RAS testing of liquid biopsy correlates with the outcome of metastatic colorectal cancer patients treated with first-line FOLFIRI plus cetuximab in the CAPRI-GOIM trial. | Normanno N et al. | โ | 2018 | โ |
| Recent Progress in Isolation and Detection of Extracellular Vesicles for Cancer Diagnostics. | Wang W et al. | โ | 2018 | โ |
| Reprint of: Circulating cell-free DNA mutation patterns in early and late stage colon and pancreatic cancer. | Vietsch EE et al. | โ | 2018 | โ |
| Review: Microfluidics technologies for blood-based cancer liquid biopsies. | Sun Y et al. | โ | 2018 | โ |
| Secondary Germline Finding in Liquid Biopsy of a Deceased Patient; Case Report and Review of the Literature. | Veyseh M et al. | โ | 2018 | โ |
| Serum circulating cell free DNA as potential diagnostic and prognostic biomarker in non small cell lung cancer. | Soliman SE et al. | โ | 2018 | โ |
| Systems biology primer: the basic methods and approaches. | Tavassoly I et al. | โ | 2018 | โ |
| Targeted deep sequencing of circulating tumor DNA in metastatic pancreatic cancer. | Berger AW et al. | โ | 2018 | โ |
| Temporal patterns of circulating cell-free DNA (cfDNA) in a newborn piglet model of perinatal asphyxia. | Manueldas S et al. | โ | 2018 | โ |
| The characteristics of ctDNA reveal the high complexity in matching the corresponding tumor tissues. | Yang N et al. | โ | 2018 | โ |
| The clinical characteristics and prognostic analysis of Chinese advanced NSCLC patients based on circulating tumor DNA sequencing. | Rao C et al. | โ | 2018 | โ |
| The Clinical Impact of Comprehensive Genomic Testing of Circulating Cell-Free DNA in Advanced Lung Cancer. | Laufer-Geva S et al. | โ | 2018 | โ |
| The dawn of the liquid biopsy in the fight against cancer. | Domรญnguez-Vigil IG et al. | โ | 2018 | โ |
| The liquid biopsy in the management of colorectal cancer patients: Current applications and future scenarios. | Normanno N et al. | โ | 2018 | โ |
| The presence of tumor extrachomosomal circular DNA (ecDNA) as a component of liquid biopsy in blood. | Khatami F et al. | โ | 2018 | โ |
| The reality of complexity: concomitant genomic alterations in patients with <i>EGFR</i> mutations. | Cardona AF et al. | โ | 2018 | โ |
| The role of plasma miRNAs in the diagnosis of pulmonary nodules. | Xi KX et al. | โ | 2018 | โ |
| The Significance of Liquid Biopsy in Pancreatic Cancer. | Qi ZH et al. | โ | 2018 | โ |
| The Use of Microfluidic Technology for Cancer Applications and Liquid Biopsy. | Kulasinghe A et al. | โ | 2018 | โ |
| The Utility of Liquid Biopsy in Central Nervous System Malignancies. | Nevel KS et al. | โ | 2018 | โ |
| TNER: a novel background error suppression method for mutation detection in circulating tumor DNA. | Deng S et al. | โ | 2018 | โ |
| Transvaginal fast-scanning optical-resolution photoacoustic endoscopy. | Qu Y et al. | โ | 2018 | โ |
| Tumor-derived microRNAs induce myeloid suppressor cells and predict immunotherapy resistance in melanoma. | Huber V et al. | โ | 2018 | โ |
| Tumor-specific methylations in circulating cell-free DNA as clinically applicable markers with potential to substitute mutational analyses. | Andersen RF | โ | 2018 | โ |
| Ultrasensitive quantification of tumor mRNAs in extracellular vesicles with an integrated microfluidic digital analysis chip. | Zhang P et al. | โ | 2018 | โ |
| Unfavorable Pathology, Tissue Biomarkers and Genomic Tests With Clinical Implications in Prostate Cancer Management. | Nguyen JK et al. | โ | 2018 | โ |
| Unmasking molecular profiles of bladder cancer. | Piao XM et al. | โ | 2018 | โ |
| Update on the types and usage of liquid biopsies in the clinical setting: a systematic review. | Arneth B | โ | 2018 | โ |
| Validation and comparison of two NGS assays for the detection of EGFR T790M resistance mutation in liquid biopsies of NSCLC patients. | Vollbrecht C et al. | โ | 2018 | โ |
| Accuracy and clinical influence of plasma EGFR mutation detection in management of advanced lung adenocarcinoma. | Ma M et al. | โ | 2017 | โ |
| An improved digital polymerase chain reaction protocol to capture low-copy KRAS mutations in plasma cell-free DNA by resolving 'subsampling' issues. | Ono Y et al. | โ | 2017 | โ |
| Application of liquid biopsy in precision medicine: opportunities and challenges. | Wang J et al. | โ | 2017 | โ |
| Assessment of circulating copy number variant detection for cancer screening. | Molparia B et al. | โ | 2017 | โ |
| [Association of RAS mutations in circulating cell-free DNA in the plasma with clinicopathological features of colorectal cancer]. | Wu J et al. | โ | 2017 | โ |
| Biomarkers for early diagnosis, prognosis, prediction, and recurrence monitoring of non-small cell lung cancer. | Tang Y et al. | โ | 2017 | โ |
| Cell free DNA analysis by SiRe<sup>ยฎ</sup> next generation sequencing panel in non small cell lung cancer patients: focus on basal setting. | Pisapia P et al. | โ | 2017 | โ |
| Cell-free DNA: Treasure trove for cancer medicine. | Taniฤ M et al. | โ | 2017 | โ |
| Cell-free mitochondrial DNA copy number variation in head and neck squamous cell carcinoma: A study of non-invasive biomarker from Northeast India. | Kumar M et al. | โ | 2017 | โ |
| Characterization and Separation of Cancer Cells with a Wicking Fiber Device. | Tabbaa SM et al. | โ | 2017 | โ |
| Chromosome 1q21.3 amplification is a trackable biomarker and actionable target for breast cancer recurrence. | Goh JY et al. | โ | 2017 | โ |
| Circular RNA maps paving the road to biomarker development? | Gรถrlach A et al. | โ | 2017 | โ |
| Circulating cell-free DNA mutation patterns in early and late stage colon and pancreatic cancer. | Vietsch EE et al. | โ | 2017 | โ |
| Circulating tumor cells and CDX models as a tool for preclinical drug development. | Lallo A et al. | โ | 2017 | โ |
| Circulating tumor DNA shows variable clonal response of breast cancer during neoadjuvant chemotherapy. | Kim JY et al. | โ | 2017 | โ |
| Colorectal adenoma and cancer detection based on altered methylation pattern of SFRP1, SFRP2, SDC2, and PRIMA1 in plasma samples. | Bartรกk BK et al. | โ | 2017 | โ |
| Combination of antibody-coated, physical-based microfluidic chip with wave-shaped arrays for isolating circulating tumor cells. | Chen H et al. | โ | 2017 | โ |
| Comparison of quantification algorithms for circulating cell-free DNA methylation biomarkers in blood plasma from cancer patients. | de Vos L et al. | โ | 2017 | โ |
| Conventional real-time PCR-based detection of T790M using tumor tissue or blood in patients with EGFR TKI-resistant NSCLC. | Wu YL et al. | โ | 2017 | โ |
| Current and Emerging Applications of Droplet Digital PCR in Oncology. | Olmedillas-Lรณpez S et al. | โ | 2017 | โ |
| Detection of genetic alterations in cfDNA as a possible strategy to monitor the neoplastic progression of Barrett's esophagus. | Rumiato E et al. | โ | 2017 | โ |
| Detection of Rare Mutations in CtDNA Using Next Generation Sequencing. | Lv X et al. | โ | 2017 | โ |
| Distribution of circulating tumor DNA in lung cancer: analysis of the primary lung and bone marrow along with the pulmonary venous and peripheral blood. | Goto T et al. | โ | 2017 | โ |
| EGFR G796D mutation mediates resistance to osimertinib. | Zheng D et al. | โ | 2017 | โ |
| Establishing PNB-qPCR for quantifying minimal ctDNA concentrations during tumour resection. | Ehlert T et al. | โ | 2017 | โ |
| Evaluation of digital PCR for detecting low-level EGFR mutations in advanced lung adenocarcinoma patients: a cross-platform comparison study. | Gu J et al. | โ | 2017 | โ |
| Evaluation of pre-analytical conditions and comparison of the performance of several digital PCR assays for the detection of major <i>EGFR</i> mutations in circulating DNA from non-small cell lung cancers: the CIRCAN_0 study. | Garcia J et al. | โ | 2017 | โ |
| Fibrosis imaging: Current concepts and future directions. | Baues M et al. | โ | 2017 | โ |
| Further the liquid biopsy: Gathering pieces of the puzzle of genometastasis theory. | Garcรญa-Casas A et al. | โ | 2017 | โ |
| Genomic approaches to accelerate cancer interception. | Beane J et al. | โ | 2017 | โ |
| Identification of non-invasive miRNAs biomarkers for prostate cancer by deep sequencing analysis of urinary exosomes. | Rodrรญguez M et al. | โ | 2017 | โ |
| Landscape of somatic mutations in different subtypes of advanced breast cancer with circulating tumor DNA analysis. | Yi Z et al. | โ | 2017 | โ |
| Liquid biopsy in non-small cell lung cancer: a key role in the future of personalized medicine? | Pi C et al. | โ | 2017 | โ |
| Liquid biopsy in patients with hepatocellular carcinoma: Circulating tumor cells and cell-free nucleic acids. | Okajima W et al. | โ | 2017 | โ |
| Molecular Analysis of Circulating Cell-Free DNA from Lung Cancer Patients in Routine Laboratory Practice: A Cross-Platform Comparison of Three Different Molecular Methods for Mutation Detection. | Bartels S et al. | โ | 2017 | โ |
| Nanoparticles-Emerging Potential for Managing Leukemia and Lymphoma. | Vinhas R et al. | โ | 2017 | โ |
| Next-generation sequencing of circulating tumor DNA to predict recurrence in triple-negative breast cancer patients with residual disease after neoadjuvant chemotherapy. | Chen YH et al. | โ | 2017 | โ |
| Non-invasive diagnostic platforms in management of non-small cell lung cancer: opportunities and challenges. | Velcheti V et al. | โ | 2017 | โ |
| Peptide Nucleic Acid-Based Biosensors for Cancer Diagnosis. | D'Agata R et al. | โ | 2017 | โ |
| Personalized and precision medicine: integrating genomics into treatment decisions in gastrointestinal malignancies. | Au TH et al. | โ | 2017 | โ |
| Poly(3,4-ethylenedioxythiophene)-Based Nanofiber Mats as an Organic Bioelectronic Platform for Programming Multiple Capture/Release Cycles of Circulating Tumor Cells. | Yu CC et al. | โ | 2017 | โ |
| Prospective Feasibility Study for Using Cell-Free Circulating Tumor DNA-Guided Therapy in Refractory Metastatic Solid Cancers: An Interim Analysis. | Kim ST et al. | โ | 2017 | โ |
| Quantification of plasma EGFR mutations in patients with lung cancers: Comparison of the performance of ARMS-Plus and droplet digital PCR. | Wang L et al. | โ | 2017 | โ |
| Radiotherapy Dosing for Locally Advanced Non-Small Cell Lung Carcinoma: "MTD" or "ALARA"? | Ohri N | โ | 2017 | โ |
| RareVar: A Framework for Detecting Low-Frequency Single-Nucleotide Variants. | Hao Y et al. | โ | 2017 | โ |
| Reduced circulating microRNA-203 predicts poor prognosis for glioblastoma. | Chen J et al. | โ | 2017 | โ |
| Routine clinical use of circulating tumor cells for diagnosis of mutations and chromosomal rearrangements in non-small cell lung cancer-ready for prime-time? | Pailler E et al. | โ | 2017 | โ |
| Sample types applied for molecular diagnosis of therapeutic management of advanced non-small cell lung cancer in the precision medicine. | Han Y et al. | โ | 2017 | โ |
| Synthetic Circulating Cell-free DNA as Quality Control Materials for Somatic Mutation Detection in Liquid Biopsy for Cancer. | Zhang R et al. | โ | 2017 | โ |
| Targeted error-suppressed quantification of circulating tumor DNA using semi-degenerate barcoded adapters and biotinylated baits. | Alcaide M et al. | โ | 2017 | โ |
| The evidence base for circulating tumour DNA blood-based biomarkers for the early detection of cancer: a systematic mapping review. | Cree IA et al. | โ | 2017 | โ |
| [Tumour sequencing: Evolutions and revolutions]. | Piton N et al. | โ | 2017 | โ |
| Tyrosine kinase inhibitor sensitive PDGFRฮ mutations in GIST: Two cases and review of the literature. | Boonstra PA et al. | โ | 2017 | โ |
| Whole exome sequencing for determination of tumor mutation load in liquid biopsy from advanced cancer patients. | Koeppel F et al. | โ | 2017 | โ |