Genetics and alcoholism among at-risk relatives II: interest and concerns about hypothetical genetic testing for alcoholism risk.
- Authors
- Gamm, Jennifer L; Nussbaum, Robert L; Bowles Biesecker, Barbara
- Year
- 2004
- Journal
- American journal of medical genetics. Part A
- PMID
- 15214006
- DOI
- 10.1002/ajmg.a.30003
One purpose of this study was to examine hypothetical interest in genetic predisposition testing for alcoholism among at-risk relatives. Qualitative interviews and several quantitative tools were administered to 27 individuals who had at least one first-degree relative affected by alcoholism. Data analysis revealed that participants' interest in genetic testing for susceptibility to alcoholism was moderate. Lower educational level and a stronger belief in 'others' influencing health were related to participants' having a stronger interest in genetic testing. Participants' concerns about future use of genetic testing ranged from doubts about its usefulness in affecting behavior to apprehension regarding detrimental societal effects such as breaches in confidentiality and fear of being labeled an 'alcoholic.' Younger age and stronger interest in genetic testing were associated with deterministic or fatalistic beliefs, while drinking behaviors, gender, and other demographics were not. Participants questioned the utility of this type of testing. Their interest in testing and concerns about its hypothetical use may prove important for at-risk relatives who may face decisions about genetic testing in the future. Data from this study can provide direction for researchers and health care providers as genetic testing for this and other behavioral conditions emerges. Scientists and the public should address the social concerns expressed by participants, including the fear of labeling. Also, we can begin to anticipate characteristics common in those who may have fatalistic responses, and who may possibly make adverse behavior choices, to results from alcoholism susceptibility testing.
No figures extracted from this document.
No chunks — full text not yet ingested.
No entities extracted from this document yet.
No uploaded files.
No citations found.
In this knowledge base
| Title | Year | PMID |
|---|---|---|
| Using genetic information from candidate gene and genome-wide association studies in risk prediction for alcohol dependence. | 2014 | 23362995 |
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| The impact of receiving polygenic risk scores for alcohol use disorder on psychological distress, risk perception, and intentions to reduce drinking. | Driver MN et al. | — | 2023 | → |
| Teenagers and Precision Psychiatry: A Window of Opportunity. | Sabatello M et al. | — | 2021 | → |
| Genetic feedback for psychiatric conditions: Where are we now and where are we going. | Driver MN et al. | — | 2020 | → |
| Beliefs and Preferences for Medical Research Among African-Americans. | Cain GE et al. | — | 2016 | → |
| Genetic testing for the susceptibility to alcohol dependence: interest and concerns in an African American population. | Scott DM et al. | — | 2014 | → |
| Using genetic information from candidate gene and genome-wide association studies in risk prediction for alcohol dependence. | Yan J et al. | — | 2014 | → |
| Perceptions about genetic testing for the susceptibility to alcohol dependence and other multifactorial diseases. | Marshall VJ et al. | — | 2012 | → |
| Association study of dopamine D2, D4 receptor gene, GABAA receptor beta subunit gene, serotonin transporter gene polymorphism with children of alcoholics in Korea: a preliminary study. | Namkoong K et al. | — | 2008 | → |
| Familial testicular cancer: interest in genetic testing among high-risk family members. | Peters JA et al. | — | 2006 | → |