The effects of ethanol on EEG activity in males at risk for alcoholism.
- Authors
- Cohen, H L; Porjesz, B; Begleiter, H
- Year
- 1993
- Journal
- Electroencephalography and clinical neurophysiology
- PMID
- 7686471
- DOI
- 10.1016/0013-4694(93)90132-f
The present investigation examined the effects of placebo (P), low dose (LD) and high dose (HD) ethanol on EEG activity in two groups of males. One group consisted of individuals at high risk for the development of alcoholism (HR, N = 21) while the other consisted of matched, low risk (LR, N = 21) controls. Only one condition (P, LD or HD) was presented each day and condition order was randomized. For each subject, both blood alcohol level(s) (BAL) measured via breathalyzer and EEG activity, using the entire 10/20 international system, were recorded prior to and at intervals of 35, 70, 105 and 140 min after P, LD or HD administration. The Fast Fourier Transform (FFT) was used to calculate power spectral densities (PSD). Measures of relative area under the power spectral curve were obtained for each of the following frequency bands: slow alpha (SA, 7.5-10 Hz), fast alpha (FA, 10.5-13.0 Hz), slow beta (SB, 13.5-19.5 Hz) and fast beta (FB, 20-26 Hz) at electrodes: F3, F4, C3, C4, P3, P4, O1 and O2. The results of repeated measures MANOVA conducted on the normalized values of relative areas revealed that at each electrode examined, ethanol elicited significant changes only in SA activity. Risk group differences in SA activity were observed only at electrodes F3, F4 and P4. These differences were the consequence of differential ethanol effects rather than differences in baseline SA levels.(ABSTRACT TRUNCATED AT 250 WORDS)
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| Understanding alcohol use disorders with neuroelectrophysiology. | Rangaswamy M et al. | — | 2014 | → |
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| Gene-environment interplay in alcoholism and other substance abuse disorders: expressions of heritability and factors influencing vulnerability. | Palomo T et al. | — | 2004 | → |
| Age-dependent changes in electroencephalographic responses to alcohol consumption in subjects with aldehyde dehydrogenase-2 genetic variations. | Nishimura FT et al. | — | 2003 | → |
| Alcoholism risk and the P300 event-related brain potential: modality, task, and gender effects. | Reese C et al. | — | 2003 | → |
| N-methyl-D-aspartate glutamate receptors and alcoholism: reward, dependence, treatment, and vulnerability. | Krystal JH et al. | — | 2003 | → |
| Hormonally regulated alpha(4)beta(2)delta GABA(A) receptors are a target for alcohol. | Sundstrom-Poromaa I et al. | — | 2002 | → |
| Mismatch negativity in subjects at high risk for alcoholism. | Zhang XL et al. | — | 2001 | → |
| Prolonged neurophysiological effects of cumulative wine drinking. | Ilan AB et al. | — | 2001 | → |
| Visual p3 in female alcoholics. | Prabhu VR et al. | — | 2001 | → |
| Biological phenotypes associated with individuals at high risk for developing alcohol-related disorders: Part 1. | Hill SY | — | 2000 | → |
| Children of alcoholics: an update. | Lieberman DZ | — | 2000 | → |
| Genetics of the risk for alcoholism. | Schuckit MA | — | 2000 | → |
| A twin study of genetic influences on the acute adaptation of the EEG to alcohol. | O'Connor S et al. | — | 1999 | → |
| Electroencephalographic responses to alcohol challenge in Native American Mission Indians. | Ehlers CL et al. | — | 1999 | → |
| P300, alcoholism heritability, and stimulus modality. | Polich J et al. | — | 1999 | → |
| Reduced EEG alpha power in the male and female offspring of alcoholics. | Finn PR et al. | — | 1999 | → |
| The contribution of electrophysiology to knowledge of the acute and chronic effects of ethanol. | Little HJ | — | 1999 | → |
| What is inherited in the predisposition toward alcoholism? A proposed model. | Begleiter H et al. | — | 1999 | → |
| Effects of ethanol on temporal recovery of auditory-evoked potentials in individuals at risk for alcoholism. | Cohen HL et al. | — | 1998 | → |
| Individual differences in the biphasic effects of ethanol. | Holdstock L et al. | — | 1998 | → |
| Genetic markers of alcohol abuse. | Ferguson RA et al. | — | 1997 | → |
| Physiological responses in sons of alcoholics. | Finn PR et al. | — | 1997 | → |
| Alcohol effects on the heritability of EEG spectral power. | Sorbel J et al. | — | 1996 | → |
| Temporal recovery of auditory evoked potentials in individuals at risk for alcoholism. | Cohen HL et al. | — | 1996 | → |
| Genetic Influences Affecting Alcohol Use Among Asians. | Wall TL et al. | — | 1995 | → |
| Comparison of innate EEG parameters in rat lines selected for ethanol preference. | Morzorati S et al. | — | 1994 | → |