Paternal alcoholism predicts the occurrence but not the remission of alcoholic drinking: a 40-year follow-up.
- Authors
- Knop, J; Penick, E C; Nickel, E J; Mednick, S A; Jensen, P; Manzardo, A M; Gabrielli, W F
- Year
- 2007
- Journal
- Acta psychiatrica Scandinavica
- PMID
- 17919158
- DOI
- 10.1111/j.1600-0447.2007.01015.x
OBJECTIVE: To test the effects of father's alcoholism on the development and remission from alcoholic drinking by age 40. METHOD: Subjects were selected from a Danish birth cohort that included 223 sons of alcoholic fathers (high risk; HR) and 106 matched controls (low risk; LR). Clinical examinations were performed at age 40 (n = 202) by a psychiatrist using structured interviews and DSM-III-R diagnostic criteria. RESULTS: HR subjects were significantly more likely than LR subjects to develop alcohol dependence (31% vs. 16%), but not alcohol abuse (17% vs. 15%). More subjects with alcohol abuse were in remission at age 40 than subjects with alcohol dependence. Risk did not predict remission from either alcohol abuse or alcohol dependence. CONCLUSION: Familial influences may play a stronger role in the development of alcoholism than in the remission or recovery from alcoholism.
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