STAR: ultrafast universal RNA-seq aligner.
- Authors
- Dobin, Alexander; Davis, Carrie A; Schlesinger, Felix; Drenkow, Jorg; Zaleski, Chris; Jha, Sonali; Batut, Philippe; Chaisson, Mark; Gingeras, Thomas R
- Year
- 2013
- Journal
- Bioinformatics (Oxford, England)
- PMID
- 23104886
- DOI
- 10.1093/bioinformatics/bts635
- PMCID
- PMC3530905
MOTIVATION: Accurate alignment of high-throughput RNA-seq data is a challenging and yet unsolved problem because of the non-contiguous transcript structure, relatively short read lengths and constantly increasing throughput of the sequencing technologies. Currently available RNA-seq aligners suffer from high mapping error rates, low mapping speed, read length limitation and mapping biases. RESULTS: To align our large (>80 billon reads) ENCODE Transcriptome RNA-seq dataset, we developed the Spliced Transcripts Alignment to a Reference (STAR) software based on a previously undescribed RNA-seq alignment algorithm that uses sequential maximum mappable seed search in uncompressed suffix arrays followed by seed clustering and stitching procedure. STAR outperforms other aligners by a factor of >50 in mapping speed, aligning to the human genome 550 million 2 Γ 76 bp paired-end reads per hour on a modest 12-core server, while at the same time improving alignment sensitivity and precision. In addition to unbiased de novo detection of canonical junctions, STAR can discover non-canonical splices and chimeric (fusion) transcripts, and is also capable of mapping full-length RNA sequences. Using Roche 454 sequencing of reverse transcription polymerase chain reaction amplicons, we experimentally validated 1960 novel intergenic splice junctions with an 80-90% success rate, corroborating the high precision of the STAR mapping strategy. AVAILABILITY AND IMPLEMENTATION: STAR is implemented as a standalone C++ code. STAR is free open source software distributed under GPLv3 license and can be downloaded from http://code.google.com/p/rna-star/.
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| Brachiopod genome unveils the evolution of BMP signalling in bilaterian body patterning. | Lewin TD et al. | β | 2026 | β |
| Brain Acid-Soluble Protein 1 (BASP1) maintains germinal centers by regulating germinal center B cell survival. | Roberts S et al. | β | 2026 | β |
| Brain aging mediates region-specific transcriptomic alterations. | Alharbi AB | β | 2026 | β |
| Brain Pericytes and Wnt/Ξ²-Catenin Signaling Induce Functional Blood-Brain Barrier Phenotype in Human iPSC-Derived Model. | Nogueira Pinto H et al. | β | 2026 | β |
| BRD2 bridges TFIID and MOF-H4K16ac-containing nucleosomes to promote transcriptional initiation. | Zheng B et al. | β | 2026 | β |
| BRD4 promotes endodermal cell fate during mammalian lung development. | Wen H et al. | β | 2026 | β |
| Breast Cancer Reveals Latent <i>BMPR2</i>-Related Susceptibility to Pulmonary Hypertension. | Toro V et al. | β | 2026 | β |
| Breeding for climate adaptation: genetic variation and genomic selection for drought response in Scots pine. | Chaudhary R et al. | β | 2026 | β |
| Brief pulses of high-level fluid shear stress enhance metastatic potential and rapidly alter the metabolism of cancer cells. | Pope AN et al. | β | 2026 | β |
| BRRIAR lncRNA alters breast cancer risk by modulating interferon signaling in cis and in trans. | Sivakumaran H et al. | β | 2026 | β |
| Bulk and single-cell transcriptomic brain data identify overlapping processes and cell-types with human AUD and mammalian models of alcohol use. | Huggett SB et al. | β | 2026 | β |
| Cancer evolution and multi-omic profile of relapsed colorectal liver metastases after treatment. | TomΓ‘s L et al. | β | 2026 | β |
| Candidate genes underlying hypomelanistic morphs in squamate reptiles. | Beaudier P et al. | β | 2026 | β |
| CAR-adapted PIK3CD base editing enhances T cell anti-tumor potency. | Bucher P et al. | β | 2026 | β |
| Carbon source-induced changes in the transcriptional landscape of Novacetimonas hansenii. | Akhoon BA et al. | β | 2026 | β |
| Carbon starvation induces coincident capsule and cell wall remodeling in <i>Cryptococcus neoformans</i>. | Bedford E et al. | β | 2026 | β |
| Cardiac fibroblast anisotropy is determined by YAP-dependent cellular contractility and ECM production. | Pereira-Sousa D et al. | β | 2026 | β |
| CAR Intrinsic Design Pre-Shapes Transcriptional and Metabolic Networks in CAR T Cells. | Agac Cobanoglu D et al. | β | 2026 | β |
| CAR-T cells with the CD38<sup>-</sup>CD73<sup>-</sup>Tim-3<sup>-</sup>HLA-DR<sup>+</sup> phenotype predict the efficacy of tisagenlecleucel as a treatment for B cell precursor ALL. | Mikami T et al. | β | 2026 | β |
| Cascading functional water balance traits enhance wheat grain yield under terminal drought. | Sadeh R et al. | β | 2026 | β |
| Caspase-3/7 deficiency results in enhanced intestinal inflammation and reduced tumorigenesis. | Xie W et al. | β | 2026 | β |
| CaspaseΒ 5c amplifies Wnt via APC cleavage to promote intestinal homeostasis. | Jia B et al. | β | 2026 | β |
| CBP-IDRs regulate acetylation and gene expression. | Gelder KL et al. | β | 2026 | β |
| CDK9 Inhibition with enitociclib reveals influence on HERV and LINE RNA abundances in whole blood, T-, and B-Cell lines. | Dopkins N et al. | β | 2026 | β |
| CEBPB-Regulated Gastric Cell Plasticity Promotes Liver Metastasis of Gastric Cancer. | Zuo Z et al. | β | 2026 | β |
| Cell cycle follows 'pause and play' mechanism in salt and cold stress recovery in diverse plant species. | Hazelwood OS et al. | β | 2026 | β |
| CellPolaris: Transfer Learning for Gene Regulatory Network Construction to Guide Cell State Transitions. | Feng G et al. | β | 2026 | β |
| Cell type-specific epigenetic regulatory circuitry of coronary artery disease loci. | Hecker D et al. | β | 2026 | β |
| Cell-type-targeted mitochondrial transplantation rescues cell degeneration. | Ayupov T et al. | β | 2026 | β |
| Cellular fitness is determined by ribosomal protein S12-mediated release of a truncated Xrp1. | Kakemura B et al. | β | 2026 | β |
| Cellular quiescence uncouples the proteome from the transcriptome in neural stem cells. | Rossi A et al. | β | 2026 | β |
| Cellular responses to prolonged non-thermal plasma exposure in Schizosaccharomyces pombe. | Petkova M et al. | β | 2026 | β |
| CFAP20 salvages arrested RNAPII from the path of co-directional replisomes. | Uruci S et al. | β | 2026 | β |
| Chamber-specific chromatin architecture guides functional interpretation of disease-associated Cis-regulatory elements in human cardiomyocytes. | Haydar S et al. | β | 2026 | β |
| Changes in transposable elements expression in male and female mice liver throughout aging. | Hernandez-Rojas B et al. | β | 2026 | β |
| Characterisation of Bespoke Patient-Derived In Vitro Models of Ewing Sarcoma. | Roundhill EA et al. | β | 2026 | β |
| Characterization, immune cell phenotyping and differential gene expression analysis of brain metastases and primary breast cancer samples. | Gassner FJ et al. | β | 2026 | β |
| Characterization of Transcriptional, Epigenetic, and Phenotypic Plasticity and Discovery of Biomarkers in Acute and Chronic Murine Schistosomiasis Infection. | CorrΓͺa SAP et al. | β | 2026 | β |
| Characterizing breed-shared and breed-specific genetic regulatory effects of gene expression across three pig breeds. | Li X et al. | β | 2026 | β |
| Characterizing the circular RNA landscape in phloem sap of Brassica napus. | LΓΌhmann KL et al. | β | 2026 | β |
| Characterizing the metabolomes of microglia, astrocytes and neurons in ageing and Alzheimer's brains. | Yu J et al. | β | 2026 | β |
| Charting the expression landscape of human long non-coding RNAs across diverse biological contexts with LncExpDB 2.0. | Qi Y et al. | β | 2026 | β |
| Chemical cues from Agrilus biguttatus beetle larvae trigger proliferation and putative virulence gene expression of the tree pathogen Brenneria goodwinii. | Cambon MC et al. | β | 2026 | β |
| Chemically guided single-cell transcriptomics reveals sulfotransferase-mediated scaffold remodeling in securinine biosynthesis. | Choung S et al. | β | 2026 | β |
| Chemoproteomic profiling reveals histone H4 dopaminylation inhibiting cell growth. | Zhang Y et al. | β | 2026 | β |
| Chimeric brain models to study human glial-neuronal and macroglial-microglial interactions. | Jin M et al. | β | 2026 | β |
| Chitinase-3-like protein 1 depletion in glioma cells alters tumor microenvironment and normalizes neovasculature in human glioma xenografts. | Cyranowski S et al. | β | 2026 | β |
| Choroid plexus inflammation in bipolar disorder. | Figueroa Velez D et al. | β | 2026 | β |
| Chromatin accessibility landscapes define stromal cell identities across tissues. | Nooranikhojasteh A et al. | β | 2026 | β |
| Chromatin remodeler BAF maintains HBV cccDNA transcriptional competence and represents a therapeutic target. | Huang D et al. | β | 2026 | β |
| Chromatin spatial analysis by METALoci unveils sex-determining 3D regulatory hubs. | Mota-GΓ³mez I et al. | β | 2026 | β |
| Chromatin state dynamics during the Plasmodium falciparum intraerythrocytic development cycle. | Brown AS et al. | β | 2026 | β |
| Chromosome-level genome assembly and transcriptome analysis of the Ural owl, Strix uralensis Pallas, 1771. | Winter S et al. | β | 2026 | β |
| Chromosome-scale genome and lncRNA annotation of the Orange Baboon Tarantula (Pterinochilus murinus). | Zhang Y et al. | β | 2026 | β |
| Chromosome-scale genome assembly and characterization of Saccharomycopsis schoenii, a necrotrophic predatory yeast. | Kriti D et al. | β | 2026 | β |
| Chromosome-scale genome assembly of Malcolmia littorea using long-read sequencing and single-pollen genotyping technologies. | Shirasawa K et al. | β | 2026 | β |
| Chromosome-scale Genome Assembly of the Most Abundant Ectomycorrhizal Fungus Cenococcum Geophilum Reveals Massive TE Expansion and RIP Defense Mechanism. | Dauphin B et al. | β | 2026 | β |
| Chronic alcohol consumption sex-dependently affects IL-6 modulation of GABAergic synapses in the central amygdala of rhesus macaques. | Bajo M et al. | β | 2026 | β |
| Chronic enteritis triggered by diet westernization is driven by epithelial ATG16L1-mediated autophagy. | Mayr L et al. | β | 2026 | β |
| Chronic fatigue syndrome induced by environmental toxic exposure: Effects of polyhexamethyleneguanidine phosphate exposure on mitochondrial function and neural health. | Yang HS et al. | β | 2026 | β |
| Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2-EZH2-Mediated Microtubule Destabilization. | Yin J et al. | β | 2026 | β |
| Circadian gene expression in adolescents: Associations with concurrent circadian disruption and subsequent changes in cardiometabolic risk measures. | Su D et al. | β | 2026 | β |
| CircRNA-encoded protein fine-tunes ROS homeostasis and engages conserved JAK-STAT antiviral defenses in <i>Drosophila</i>. | Guo D et al. | β | 2026 | β |
| Circulating tumor DNA accelerates diagnosis and treatment guidance for metastatic uveal melanoma with hepatic lesions not amenable to biopsy. | Kissinger CR et al. | β | 2026 | β |
| Cis-regulatory architecture downstream of FLOWERING LOCUS T underlies quantitative control of flowering in Arabidopsis thaliana. | Zhou HR et al. | β | 2026 | β |
| Cis-regulatory evolution of Wnt family genes contributes to a morphological difference between silkworm species. | Tomihara K et al. | β | 2026 | β |
| c-JUN enhances CRISPR knockin anti-B7-H3 CAR T cell function in small cell lung cancer and thoracic SMARCA4-deficient undifferentiated tumors. | Balke-Want H et al. | β | 2026 | β |
| Cleavage and Polyadenylation Specificity Factor Subunit 5 Regulates Pulmonary Artery Smooth Muscle Expansion and Hypoxic Response. | Collum SD et al. | β | 2026 | β |
| Cleavage of mRNAs by a minority of pachytene piRNAs improves sperm fitness. | Cecchini K et al. | β | 2026 | β |
| Clinical and Molecular Differences of Hypertensive Disorders During Pregnancy. | Horii M et al. | β | 2026 | β |
| Clinically advanced NLRP3 inhibitor modulates microglial transcriptome and alleviates Ξ±-synuclein-induced progression of parkinsonism. | Luque M et al. | β | 2026 | β |
| CLOCK-catalyzed histone H3K37 glutarylation suppresses H3K36 trimethylation pathways in glioblastoma. | Wang Y et al. | β | 2026 | β |
| Clonal dynamics shaped by diverse drug-tolerant persister states in melanoma resistance. | Li H et al. | β | 2026 | β |
| Coastal and inland American alligators (Alligator mississippiensis) diverge along physiological axes in response to a salinity gradient. | Konvalina JD et al. | β | 2026 | β |
| Colloid-patterned surfaces distinguish malignant mechanophenotypes. | Zemmour C et al. | β | 2026 | β |
| Combined effects of incubation temperature and lipopolysaccharide exposure on immune response modulation in the quail gut. | ConceiΓ§Γ£o JDS et al. | β | 2026 | β |
| Combined inhibition of FACT and BET disrupts transcription to suppress tumor growth in mouse models of diffuse midline glioma. | Holliday H et al. | β | 2026 | β |
| Commensal microbe-derived butyrate enhances T follicular helper cell function to boost mucosal vaccine efficacy. | Ko H et al. | β | 2026 | β |
| Common tissue-specific expressions and regulatory factors of c-KIT isoforms with and without GNNK and GNSK sequences across five mammals. | Goto R et al. | β | 2026 | β |
| Community benchmarking and evaluation of human unannotated microprotein detection by mass spectrometry based proteomics. | Wacholder A et al. | β | 2026 | β |
| Comparative analysis of spatial expression patterns of ectopic olfactory receptors. | Pokharel E et al. | β | 2026 | β |
| Comparative gene annotation and orthology assignments across 301 species of Drosophilidae. | Dhakad P et al. | β | 2026 | β |
| Comparative Genomic and Transcriptomic Analysis Reveals Why Paenarthrobacter Strains Are Specialists in the Degradation of the Fungicide Iprodione. | Michelioudakis V et al. | β | 2026 | β |
| Comparative Genomics Analysis of Three Species of Root-Lesion Nematodes, <i>Pratylenchus</i> spp., Suggests an Intricate Evolutionary Origin of Effector Genes. | Ste-Croix DT et al. | β | 2026 | β |
| Comparative multi-omic analysis reveals conserved and derived mechanisms of fin and limb regeneration. | F Sousa J et al. | β | 2026 | β |
| Comparative transcriptomic analysis of embryonic stem cells across mammalian species. | Fang Y et al. | β | 2026 | β |
| Comparative transcriptomic insights into ticks infected by alongshan and tick-borne encephalitis viruses. | Ebert CL et al. | β | 2026 | β |
| Comparative transcriptomics reveal the common anteroposterior molecular blueprint of adult bilaterian guts. | Vianello SD et al. | β | 2026 | β |
| Complementary Multiomics Integration Approaches Feature a Likely Role for Salicylic Acid Biology in Accelerating Kiwiberry (<i>Actinidia arguta</i>) Fruit Development. | GΓΌnther CS et al. | β | 2026 | β |
| Composite SMG5-SMG6 PIN domain formation is essential for NMD. | Kurscheidt K et al. | β | 2026 | β |
| Comprehensive mapping of RNA modification dynamics and crosstalk via deep learning and nanopore direct RNA-sequencing. | Dong H et al. | β | 2026 | β |
| Comprehensive spatial and immune profiling of metastatic mismatch repair-deficient colorectal cancer reveals response to immunotherapy. | Park I et al. | β | 2026 | β |
| Comprehensive Transcriptome Profiling of Sporadic Medullary Thyroid Carcinomas. | Palumbo D et al. | β | 2026 | β |
| Comprehensive transcriptomic analysis reveals canonical and novel pathways modulated by nanoceria in mammalian retinal degeneration. | Donato L et al. | β | 2026 | β |
| Comprehensive transcriptomics and proteomics analysis of neointima formation in human saphenous vein: implications for bypass graft disease. | Kim DS et al. | β | 2026 | β |
| Computational identification of novel therapeutic candidates for Streptococcus pyogenes and influenza A coinfections through transcriptomic-based drug repositioning. | Strey K et al. | β | 2026 | β |
| CONSTANS-LIKE 5 facilitates flower opening and scent biosynthesis in Solanaceae. | Choi Y et al. | β | 2026 | β |
| Contaminating plasmid sequences and disrupted vector genomes in the liver following adeno-associated virus gene therapy. | Buddle S et al. | β | 2026 | β |
| Context-specific expression quantitative trait loci dynamics uncover genetic pleiotropy in schizophrenia. | Ye L et al. | β | 2026 | β |
| Control of airway basal stem cell-mediated lung repair by TGF-Ξ² signaling. | Zou T et al. | β | 2026 | β |
| Control of retrotransposon-driven activation of the interferon response by the double-stranded RNA binding protein DGCR8. | GΓ‘zquez-GutiΓ©rrez A et al. | β | 2026 | β |
| Coordinated gene family evolution shapes the genome of dimorphic Mucorales. | Tahiri G et al. | β | 2026 | β |
| Coordinated molecular and physiological adaptations enable activity at sub-freezing temperatures in the snow fly Chionea alexandriana. | Capek M et al. | β | 2026 | β |
| Cortactin Suppresses mTOR-Dependent Senescence in Circulating Tumor Cells. | Hu J et al. | β | 2026 | β |
| Cosmopolitan Gene Families With Known Functions Are Hotspots for the Evolution of Novel Genes in Stony Corals. | Stephens TG et al. | β | 2026 | β |
| Co-transcriptional splicing changes combine with reduced productive transcription initiation for cold-induced repression of FLC. | Maple R et al. | β | 2026 | β |
| Counteracting FOX proteins epigenetically control the herpesvirus lytic-latent balance. | Xiang Y et al. | β | 2026 | β |
| Covalent inhibitor design confers activity against both GDP- and GTP-bound forms of KRAS G12C. | Condakes ML et al. | β | 2026 | β |
| Creating a new oilseed crop, pennycress, by combining key domestication traits using CRISPR genome editing. | Gautam B et al. | β | 2026 | β |
| CRISPR-based functional analysis of chicken IRF9 reveals distinct modulation of dsRNA stimulated innate immune pathways. | Schmidt GE et al. | β | 2026 | β |
| CRISPR-induced knockouts reveal a dual role for the soybean NFR5Ξ± gene in symbiotic nitrogen fixation and root hair development. | Niazian M et al. | β | 2026 | β |
| CRISPR knockout screens reveal genes and pathways essential for neuronal differentiation and implicate PEDS1 in neurodevelopment. | Amelan A et al. | β | 2026 | β |
| CRISPR screen of human pancreatic cancer xenografts identifies a KLF5 proliferation vulnerability through epigenetic modifiers NCAPD2 and MTHFD1. | Maeda M et al. | β | 2026 | β |
| CRISPR screens in the context of immune selection identify CHD1 and MAP3K7 as mediators of cancer immunotherapy resistance. | Watterson A et al. | β | 2026 | β |
| Cross-Species Analysis of Transcriptomic Response to Alpha-Herpesvirus Infection in Human, Bovine and Equine Cells. | Schmitz M et al. | β | 2026 | β |
| CSRefiner: a lightweight framework for fine-tuning cell segmentation models with small datasets. | Shi C et al. | β | 2026 | β |
| C-Terminal Truncation and Fusion Partner Determine Oncogenicity of FGFR3. | Yemelyanenko J et al. | β | 2026 | β |
| Curcumin-based benzothiazepane analogues exhibit selective anti-cancer activity in HCT-116 cells via precipitated particle formation and internalisation. | De Munck J et al. | β | 2026 | β |
| Cutaneous human papillomavirus E6 impairs the cGAS-STING pathway. | Brooke G et al. | β | 2026 | β |
| CXCR6+ T cells promote apoptosis and necroptosis in proximal tubules during AKI-to-CKD transition. | Li X et al. | β | 2026 | β |
| Cytoarchitectural multi-depot profiling reveals immune-metabolic crosstalk in human colon-associated adipose tissue. | Jalkanen J et al. | β | 2026 | β |
| Cytoplasmic mRNA decay by the antiviral nuclease RNase L promotes transcriptional repression. | Mao X et al. | β | 2026 | β |
| Cytosine methylation contributes to the fitness of <i>Caulobacter</i> cells naturally expressing a Vsr-like protein. | Matthey N et al. | β | 2026 | β |
| Data-driven design of LNA-blockers for efficient contaminant removal in Ribo-Seq libraries. | Ricciardi DA et al. | β | 2026 | β |
| DCMiC: a double-cylinder micro-chamber platform for high-throughput drug screening and modeling of microenvironmental resistance in Ewing sarcoma. | Lee J et al. | β | 2026 | β |
| Deciphering the interaction between osteosarcoma and mesenchymal stem cells in a 3D bone-mimetic co-culture model. | Bassi G et al. | β | 2026 | β |
| Deciphering the Role of Cancer Stem Cells in Breast Cancer Brain Colonization Using a Novel Patient-Derived Model. | Faletti S et al. | β | 2026 | β |
| Decoding cytokine networks in ulcerative colitis to identify pathogenic mechanisms and therapeutic targets. | Olbei M et al. | β | 2026 | β |
| Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth. | Jiang H et al. | β | 2026 | β |
| Decoding the heterogeneity of human undifferentiated spermatogonia reveals RAS-dependent regulation of stem cell fate. | Capponi C et al. | β | 2026 | β |
| Decoding the interconnected splicing patterns of hepatitis B virus and host using large language and deep learning models. | Lim CS et al. | β | 2026 | β |
| Decoding the molecular logic of rapidly evolving ZAD zinc finger proteins in <i>Drosophila</i>. | Saito R et al. | β | 2026 | β |
| Deep Sequence Characterization of Tomato Spotted Wilt Virus in Cultivated and Wild-Derived Allotetraploid Peanuts in Georgia, U.S.A. | Maharjan N et al. | β | 2026 | β |
| Defective Trophoblast Differentiation, Endothelial Dysfunction, and Immune Dysregulation in Preeclampsia Coalesce on a Placental VGLL3-Centered Gene Network. | Plazyo O et al. | β | 2026 | β |
| Deficiency of <i>ZC3HC1</i> Modulates Vascular Smooth Muscle Cell Phenotype and Increases Neointima Formation. | Aherrahrou R et al. | β | 2026 | β |
| Defining subcellular synovial responses in TMJ osteoarthritis onset via mechanical stress and articular disk derangement models. | Shibusaka K et al. | β | 2026 | β |
| Delayed transcriptional response of Daphnia pulex to thermal stress. | Backenstose NJC et al. | β | 2026 | β |
| Delineation of the heterogeneity underlying genomic instability in hereditary breast cancers reveals four disease subtypes. | Kim S et al. | β | 2026 | β |
| De Novo Gene Transcription of Connexin Mediates Cytoplasmic Fluid Exchange and Flocking Transitions in Physiological and Cancerous Epithelial Systems. | Abdo H et al. | β | 2026 | β |
| De novo genome assembly of Ansell's mole-rat (Fukomys anselli). | Bekavac M et al. | β | 2026 | β |
| Deoxynivalenol disrupts male mice reproduction through gut-testis axis dysregulation and metabolic alterations. | Dong PY et al. | β | 2026 | β |
| Derepression of a single microRNA target causes female infertility in mice. | Stefano J et al. | β | 2026 | β |
| Designing 5' UTR sequences improves the capacity of mRNA therapeutics in preclinical models of aging and obesity. | Yoon S et al. | β | 2026 | β |
| Designing RNA sequencing experiments: A practical guide to reproducible gene expression analysis. | Antoszewski K et al. | β | 2026 | β |
| Detection of alternative splicing: deep sequencing or deep learning? | Hackl LM et al. | β | 2026 | β |
| Developmental convergence and divergence in human stem cell models of autism. | Gordon A et al. | β | 2026 | β |
| Developmental plasticity enables an intestinal tapeworm to adapt to dietary stress. | JirkΕ― M et al. | β | 2026 | β |
| Development and characterization of an inducible Tensin1 deficient transgenic murine model. | Bernau K et al. | β | 2026 | β |
| Development and characterization of immortalized mouse intestinal epithelial cell lines. | Zhou JY et al. | β | 2026 | β |
| Development of a DUX4-targeting antibody oligonucleotide conjugate as a therapy for FSHD. | Malecova B et al. | β | 2026 | β |
| Development of a Flex-Seq SNP panel for raspberry (Rubus idaeus L.) and validation through linkage map construction and identification of QTL for several traits of agronomic importance to raspberry breeding. | Davik J et al. | β | 2026 | β |
| Development of genomic resources and assays for immune repertoire profiling in Syrian hamsters. | Adams N et al. | β | 2026 | β |
| Development of low-cost electrical stimulation device to promote hiPSC-CM differentiation and functionality. | Kalkunte N et al. | β | 2026 | β |
| Diagnostic potential of cryptic exon-derived peptides in serum extracellular vesicles for sporadic amyotrophic lateral sclerosis. | Takahashi K et al. | β | 2026 | β |
| Diel transcriptional dynamics of a marine sponge and its microbiome in a natural environment. | RamΓrez GA et al. | β | 2026 | β |
| Diet and temperature interactively impact brown adipose tissue gene regulation controlled by DNA methylation. | Hagemann T et al. | β | 2026 | β |
| Dietary sulfur amino acid restriction elicits a cold-like transcriptional response in inguinal but not epididymal white adipose tissue of male mice. | Ruppert PMM et al. | β | 2026 | β |
| Differential downstream signaling in microglia lacking Alzheimer's-related TREM2 or its adaptor TYROBP/DAP12. | Farias Quipildor GE et al. | β | 2026 | β |
| Differential expression of proanthocyanidin-related candidate genes in contrasting seed coat colors of Chilean common bean landraces under deficit irrigation. | RodrΓguez-Alvarez Y et al. | β | 2026 | β |
| Differential roles of the type I and II secretion systems for the intracellular ABC141 Acinetobacter baumannii infection, which elicits an atypical hypoxia response in endothelial cells. | Debruyne C et al. | β | 2026 | β |
| Differential transcriptomic and circadian regulation across giant kelp blades based on relative tissue age. | Chandra MI et al. | β | 2026 | β |
| Differential transcriptomic modulation by histone deacetylase inhibitor SAHA in LUAD and LUSC. | Wang F et al. | β | 2026 | β |
| Dilated cardiomyopathy-associated RNA-binding motif protein 20 regulates long pre-mRNAs in neurons. | Di Bartolomei G et al. | β | 2026 | β |
| Diploid hepatocytes resist acetaminophen-induced liver injury through suppressed JNK signaling. | Wilson SR et al. | β | 2026 | β |
| Directed differentiation of functional corticospinal-like neurons from endogenous SOX6+/NG2+ cortical progenitors. | Ozkan A et al. | β | 2026 | β |
| DIS3 mutations enhance AID-driven translocations during B-cell activation, promoting transformation to multiple myeloma. | KuliΕski TM et al. | β | 2026 | β |
| Discovery of an ITK and TRK kinase inhibitor for the potential topical treatment of atopic dermatitis. | Duffen JL et al. | β | 2026 | β |
| Discovery of kidney disease targets using multimodal human podocyte injury models. | Barreto AD et al. | β | 2026 | β |
| Disease tolerance and infection pathogenesis age-related tradeoffs in mice. | Sanchez KK et al. | β | 2026 | β |
| Dissecting genetic and immune drivers of heterogeneous responses to neoadjuvant immunochemotherapy in gastric cancer. | Zhao Q et al. | β | 2026 | β |
| Dissecting PGE<sub>2</sub>-driven inhibition of T cell activation using single-cell multi-omic and inflammatory bowel disease genetic association analysis. | Xu Z et al. | β | 2026 | β |
| Dissecting the development of bovine testicular tissue using spatial transcriptomics. | Jin H et al. | β | 2026 | β |
| Dissecting the genetic basis of climatic adaptation in wild relatives (Malus baccata) for climate-resilient apple breeding. | Su Y et al. | β | 2026 | β |
| Dissecting the homeodomain <i>MAT</i> locus and engineering novel tripolar and bipolar mating systems in <i>Cryptococcus amylolentus</i>. | Xiong L et al. | β | 2026 | β |
| Dissecting the immunosuppressive microenvironment of LAMA3β+βmalignant cells and SPP1β+βmacrophages in esophageal squamous cell carcinoma using single-cell and spatial transcriptomics. | Hong K et al. | β | 2026 | β |
| Distinct blood transcriptomic profiling underlying asthma establishment and exacerbation. | Wu B et al. | β | 2026 | β |
| Distinct by Design: Unraveling the Unique Clinical and Transcriptomic Identity of Juvenile Scleromyositis Overlap Compared to Juvenile Systemic Sclerosis and Juvenile Dermatomyositis: Implications for Care and Pathogenesis. | Robinson AD et al. | β | 2026 | β |
| Distinct regulatory elements of SLC6A14 expression contribute to modification of cystic fibrosis phenotypes. | Esmaeili M et al. | β | 2026 | β |
| Distinct roles for SETΞ± and SETΞ² in early cell fate decisions. | Lim PSL et al. | β | 2026 | β |
| Distinct steps of nuclear maturation of human pre-60S complexes require the activity of GTPases including GNL3L. | ThomΓ© CC et al. | β | 2026 | β |
| Distinct sympathetic projections to brown fat regulate thermogenesis and glucose tolerance. | Neri D et al. | β | 2026 | β |
| Divergent immune strategies of Colorado potato beetle larvae against the entomopathogenic fungi Metarhizium robertsii and Beauveria bassiana: A comparative transcriptomic analysis. | Kryukov V et al. | β | 2026 | β |
| Divergent stem cell mechanisms govern the primary body axis and appendage regeneration in the axolotl. | Wang L et al. | β | 2026 | β |
| Divergent Transcriptional Architectures Beyond Core CAM Genes in Facultative and Constitutive CAM Species in Tillandsia L. | Groot-Crego C et al. | β | 2026 | β |
| Divergent tumor immunity determined by bacteria-cancer cell engagement. | Yao B et al. | β | 2026 | β |
| Diving Deeper Into Mechanisms of Acrylamide-Induced Toxicity: RNA Sequencing Reveals Transcriptomic Alteration and Retrotransposon Expression in Drosophila melanogaster. | Farodoye OM et al. | β | 2026 | β |
| DNA methylation reflects tissue and caste identity but not parasitism-induced changes in a social insect. | Blasi G et al. | β | 2026 | β |
| Domain-specific mechanisms of YAP1 variants in ocular coloboma revealed by in-vitro and organoid studies. | Silvano S et al. | β | 2026 | β |
| Dominance modifiers at the Arabidopsis self-incompatibility locus retain proto-miRNA features and act through non-canonical pathways. | A Batista R et al. | β | 2026 | β |
| DoTT-ML: Condition-aware detection of transcriptional readthrough from RNA-seq with optional ML-based prioritization. | Levin M et al. | β | 2026 | β |
| Drug screening on tumor organoids exposes therapeutic vulnerabilities of meningiomas to HDAC1/2i panobinostat. | Jungwirth G et al. | β | 2026 | β |
| Dual transcriptional analysis provides insights into the replicative niche of <i>P. salmonis</i> and the host response during infection. | Aravena P et al. | β | 2026 | β |
| Dynamic allele usage of X-linked genes ameliorates neurodevelopmental disease phenotypes in brain organoids. | Bertin M et al. | β | 2026 | β |
| Dynamic and cell-type specific transcriptional reprogramming underlies the floral transition in the maize shoot apical meristem. | Dong L et al. | β | 2026 | β |
| Dynamic and extensive A-to-I RNA recoding in immunoglobulin shapes myeloid neoplasm transcriptome. | Cao Q et al. | β | 2026 | β |
| Dynamic and Ongoing De Novo L1 Retrotransposition Contributes to Genome Plasticity and Intrapatient Heterogeneity in Ovarian Cancer. | Pradhan B et al. | β | 2026 | β |
| Dynamic changes in circulating microRNAs during oral glucose tolerance testing support their potential as diagnostic and monitoring biomarkers in cystic fibrosis-related diabetes. | Westholm E et al. | β | 2026 | β |
| Dynamic chromatin regulatory programs of sucrose and citric acid metabolism during fruit ripening in Citrus. | Song X et al. | β | 2026 | β |
| Dynamic feedback control of oncogenic tyrosine kinase signaling in acute leukemia. | Lee J et al. | β | 2026 | β |
| Dysregulation of human corneal miRNAs and their cognate targets in Fusarium spp. keratitis and its implication in disease progression. | Dinesh S et al. | β | 2026 | β |
| E7<sub>11-19</sub> placement and orientation dictate CD8<sup>+</sup> T cell response in structurally defined spherical nucleic acid vaccines. | Hwang J et al. | β | 2026 | β |
| Early IKKΞ²-Dependent Anabolic Signature Governs Vascular Smooth Muscle Cells Fate and Abdominal Aortic Aneurysm Development. | Doyon P et al. | β | 2026 | β |
| Early innate immune response to highly pathogenic avian influenza and functional characterisation of the chicken IRF1 promoter. | Smith AJ et al. | β | 2026 | β |
| EcDNA-borne structural variants drive oncogenic fusion transcript amplification. | Yi H et al. | β | 2026 | β |
| Effect of alendronate on survival and bone properties in Nothobranchius furzeri: insights from a model of accelerated aging. | Butylina M et al. | β | 2026 | β |
| Effect of antibody-dependent enhancement on the development of the offspring of mice infected by Zika virus: Analysis of the brain transcriptome. | Azevedo LMS et al. | β | 2026 | β |
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| Efficient LAMA1 Gene Activation by Epigenome Editing as a Therapeutic Approach for LAMA2-CMD. | Qin Y et al. | β | 2026 | β |
| EIF5A Couples Translational Control With Transcriptional Reprogramming Through Chromocenter Reorganization During Spermiogenesis. | Cai Y et al. | β | 2026 | β |
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| Electrophilic compound screening identifies GPX4-dependent ferroptosis as a senescence vulnerability. | D'Ambrosio M et al. | β | 2026 | β |
| Electrophysiological development and functional plasticity in dissociated human cerebral organoids across multiple cell lines. | Pavlinek A et al. | β | 2026 | β |
| Electrostatic properties of disordered regions control transcription factor search and pioneer activity. | Sakong S et al. | β | 2026 | β |
| Elucidation of gene clusters underlying withanolide biosynthesis in ashwagandha through yeast metabolic engineering. | Reynolds EE et al. | β | 2026 | β |
| Embigin is involved in the regulation of early mouse kidney development. | Talvi S et al. | β | 2026 | β |
| Embryonic Hormetic Priming Modulates Later-Life Thermal Tolerance. | Lugue K et al. | β | 2026 | β |
| Emergence of high-metastatic potentials and prediction of recurrence and metastasis. | Srinivasan A et al. | β | 2026 | β |
| Empiric azithromycin alters the upper respiratory microbiome and resistome without anti-inflammatory benefit in COVID-19. | Glascock A et al. | β | 2026 | β |
| Endogenous promoter G-quadruplexes scaffold apurinic/apyrimidinic endonuclease (APE1) to drive gene expression. | Chen Y et al. | β | 2026 | β |
| Endogenous retroviruses synthesize heterologous chimeric RNAs to reinforce human early embryo development. | Xiang Y et al. | β | 2026 | β |
| Endometrial cortisol level and its relationship with psychological stress, molecular tissue changes, and clinical outcomes in infertile women. | Marti-Garcia D et al. | β | 2026 | β |
| Endothelial <i>Adgrl2</i> Expression and Alternative Splicing Controls the Cerebrovasculature. | King A et al. | β | 2026 | β |
| Endothelial stem cells of the retinal vasculature reside in the optic nerve. | Sakimoto S et al. | β | 2026 | β |
| Engineered T cell therapy for the treatment of cardiac fibrosis during chronic phase of myocarditis. | Hua X et al. | β | 2026 | β |
| Enhanced myelination potential of human mature oligodendrocytes by TNF and IFNG combination. | Mohammadnia A et al. | β | 2026 | β |
| Enhancing gene therapy vectors manufacturing: CEBPA as a master regulator of rAAV biogenesis. | Moura F et al. | β | 2026 | β |
| Enoyl-CoA hydratase genes underlie natural variation of lactones in cultivated and wild strawberries. | Porter M et al. | β | 2026 | β |
| Enteral Feeding With Omega-3 Polyunsaturated Fatty Acids Mitigates Liver Injury Following Massive Intestinal Resection. | Phelps HM et al. | β | 2026 | β |
| Enterobacter sp. SA187 boosts high-affinity nitrate transporters expression, ethylene signaling, and plant growth under low nitrate. | Ilyas A et al. | β | 2026 | β |
| Entrectinib attenuates LPS-induced neuroinflammation by inhibiting JNK, p38, and AKT pathways and ameliorates cognitive impairment. | Woo H et al. | β | 2026 | β |
| Enzyme-enhanced RNA isolation from biofilm-producing bacteria. | Felton SM et al. | β | 2026 | β |
| Epigenetic alterations of AKT1 orchestrate a metabolic reprogramming in advanced lipedema: translational insights from an integrated multi-omics study. | Santella B et al. | β | 2026 | β |
| Epigenetic and Transcriptional Programs Define Osteosarcoma Subtypes and Establish Targetable Vulnerabilities. | LΓ³pez-Fuentes E et al. | β | 2026 | β |
| Epigenetic context defines the transcriptional activity of canonical and noncanonical NF-ΞΊB signaling in pancreatic cancer. | Aggrey-Fynn JE et al. | β | 2026 | β |
| Epigenetic dysregulation of IRF9 drives excessive interferon signaling in COPD. | Llamazares-Prada M et al. | β | 2026 | β |
| Epigenetic memory of colitis promotes tumour growth. | Nagaraja S et al. | β | 2026 | β |
| Epigenetic profiling of hematopoietic stem cells from male mice identifies KDR and PU.1 as regulators of aging transcriptome and caloric restriction response. | Zong L et al. | β | 2026 | β |
| Epigenomic subtypes of late-onset Alzheimer's disease reveal distinct microglial signatures. | Laroche VT et al. | β | 2026 | β |
| Epigenomic, transcriptomic, and proteomic characterization of breast cancer cell line reference samples. | Nepal C et al. | β | 2026 | β |
| Epithelial-mesenchymal plasticity and immunosuppression in canine carcinomas reveals cross-species upregulation of CD109. | Bakhle K et al. | β | 2026 | β |
| Equine endometrial organoids preserve tissue structure and cycle-stage transcriptional identityβ . | Verstraete MH et al. | β | 2026 | β |
| Ergosterol suppresses NLRP3 inflammasome-mediated inflammatory responses through Bmal1. | Nguyen PL et al. | β | 2026 | β |
| Escherichia coli promotes colorectal cancer metastasis by maintaining enhancer-promoter loops through releasing neutrophil extracellular traps. | Pan B et al. | β | 2026 | β |
| Estropausal gut microbiota transplant improves measures of ovarian function in adult mice. | Kim M et al. | β | 2026 | β |
| Eukan: a fully automated nuclear genome annotation pipeline for less studied and divergent eukaryotes. | Sarrasin M et al. | β | 2026 | β |
| Evidence of an allostatic response by intestinal tissues following induction of joint inflammation. | Moran MM et al. | β | 2026 | β |
| Evolutionary Dynamics of Dosage Compensation and Sex-biased Gene Expression in Morabine Grasshopper Vandiemenella viatica. | Jayaprasad S et al. | β | 2026 | β |
| Evolutionary Dynamics of Gene Expression During Thermal Adaptation in Drosophila subobscura. | Antunes MA et al. | β | 2026 | β |
| Evolutionary transcriptomics unveils rapid changes of gene expression patterns in flowering plants. | Schuster C et al. | β | 2026 | β |
| Evolution of Plasticity in Response to Ethanol Between Recently Separated Populations of <i>D. melanogaster</i> With Different Ecological Histories. | Boateng-Sarfo G et al. | β | 2026 | β |
| Excitation-contraction coupling, cardiomyocyte electrophysiology, and transcriptome profiles in two HFpEF murine models: etiology and sex-dependent differences. | Hegyi B et al. | β | 2026 | β |
| Exclusion of Notch from the contact site during efferocytosis restricts anticancer immunity. | Li Z et al. | β | 2026 | β |
| Expanding the human proteome with microproteins and peptideins. | Deutsch EW et al. | β | 2026 | β |
| Expansion of the geranylgeranyl pyrophosphate synthase gene family underlies the evolution of terpenoid biosynthesis in termites. | HorΓ‘Δek N et al. | β | 2026 | β |
| Exploratory RNA Sequencing Reveals Systemic Metabolic Dysregulation in Alzheimer's Disease: Insights from a Diverse Latin American Cohort. | Villegas-Trujillo LM et al. | β | 2026 | β |
| Exploring leaf variegation in Arabidopsis yellow variegated2 by single-cell RNA sequencing. | Chai X et al. | β | 2026 | β |
| Expression heterosis in the abaca (Musa textilis NΓ©e) BC<sub>2</sub> hybrid, Dioscoro 1. | Ereful NC et al. | β | 2026 | β |
| Expression of endogenous retroviral elements is associated with extracellular matrix remodeling in prostate cancer. | Williams EC et al. | β | 2026 | β |
| Expression, regulation, and multifaceted molecular and biological functions of sirtuin 6 in the porcine endometrium during early pregnancy. | Szymanska M et al. | β | 2026 | β |
| Extensive enhancer crosstalk controls PPARG2 activation during adipogenesis. | Cetnarowska A et al. | β | 2026 | β |
| EZH2 directs HER2+ breast cancer progression through the modulation of epithelial plasticity. | Liu L et al. | β | 2026 | β |
| Faecalibacterium prausnitzii, depleted in the Parkinson's disease microbiome, improves motor deficits in Ξ±-synuclein overexpressing mice. | Moiseyenko A et al. | β | 2026 | β |
| Febrile temperature activates the innate immune response by promoting aberrant influenza A virus RNA synthesis. | Bisht K et al. | β | 2026 | β |
| Feed-forward loops by NR5A2 ensure robust gene activation during pre-implantation development. | Kobayashi W et al. | β | 2026 | β |
| Female-Biased VSMC GRNs Predict MYH9 as Regulator of Fibrous Plaque Phenotype. | Perry RN et al. | β | 2026 | β |
| Female-biased vulnerability to transgenerational impact of paternal early-life stress. | Ishikawa I et al. | β | 2026 | β |
| Female sex is a risk factor for exacerbated lipid peroxidation and disease in murine retinitis pigmentosa. | VainionpÀÀ K et al. | β | 2026 | β |
| Ferroptotic tumor cells reprogram tumor-associated macrophage antigen presentation to enhance the efficacy of immune checkpoint blockade. | Sun JL et al. | β | 2026 | β |
| FLASH radiotherapy preserves systemic and tissue homeostasis while maintaining antitumor efficacy. | Furini G et al. | β | 2026 | β |
| FOXM1 expression is induced by the brain microenvironment and supports CRC brain metastatic adaptation. | Khair F et al. | β | 2026 | β |
| Foxp3 and BATF cooperatively direct cis-regulatory programs and gene expression for effector Treg cell differentiation. | Murakami R et al. | β | 2026 | β |
| From Adam's rib: the Siberian moth's female W chromosome is derived from its Z counterpart. | Shipova AA et al. | β | 2026 | β |
| From omics to enhanced fungal virulence: overexpression of a putative secreted protein improves Beauveria bassiana biocontrol potential against the insect pest Piezodorus guildinii. | Oberti H et al. | β | 2026 | β |
| Functional and molecular characterization of equine intestinal organoids across media conditions and intestinal segments. | Richardson LM et al. | β | 2026 | β |
| Functional dissection of complex trait variants at single-nucleotide resolution. | Siraj L et al. | β | 2026 | β |
| Functional genomic analysis of non-canonical DNA regulatory elements of the aryl hydrocarbon receptor. | Shahriar S et al. | β | 2026 | β |
| Functional genomic profiling of schizophrenia-associated genes reveals key microglial regulators. | Horng JE et al. | β | 2026 | β |
| Functional germline variants together with somatic mutations alter the integrity of cancer hallmark regulatory networks. | Dai J et al. | β | 2026 | β |
| Functional implications of polygenic risk for schizophrenia in human neurons. | Michael Deans PJ et al. | β | 2026 | β |
| GABA enhances broad bean aluminum tolerance via reducing uptake and reinforcing lignin and (iso)flavonoid synthesis. | Tang H et al. | β | 2026 | β |
| Gain and loss of gene function shaped the nickel hyperaccumulation trait in Noccaea caerulescens. | Belloeil C et al. | β | 2026 | β |
| Gender-specific perspectives in schizophrenia: Recent advances and future directions. | Ansari SA et al. | β | 2026 | β |
| Gene expression analysis reveals distinct PHB depolymerization mechanisms and broader involvement of the PHB cycle in Rhodospirillum rubrum growing on acetate and fructose. | Fleuriot-Blitman H et al. | β | 2026 | β |
| Gene expression differentiation is consistent with local adaptation across an elevational gradient in Drummond's rockcress (Boechera stricta). | Tisinai SL et al. | β | 2026 | β |
| Generation of a comprehensive epigenomic atlas in clear cell renal cell carcinoma informs kidney cancer progression and heritability. | Abou Alaiwi S et al. | β | 2026 | β |
| Generation of human pineal gland organoids with melatonin production for disease modeling. | Kiral FR et al. | β | 2026 | β |
| Genetically encoded fluorescent reporters to visualize Ξ±-synuclein pathology in live brain. | Zhang L et al. | β | 2026 | β |
| Genetic alternative splicing regulation mapping of cartilage and synovium reveals tissue-specific mechanisms of joint-related traits. | Tian W et al. | β | 2026 | β |
| Genetic control of non-coding RNAs in the human brain and their implications for complex traits. | Chen L et al. | β | 2026 | β |
| Genetic disruption of leucine rich repeat transmembrane protein 4 like 1 induces a pro-social behavioural phenotype in zebrafish. | Hillman C et al. | β | 2026 | β |
| Genetic diversity of Collaborative Cross mice implicates FFAR3 as a target for ILC2 anti-inflammatory reprogramming. | Rusznak M et al. | β | 2026 | β |
| Genetic landscape of pediatric acute myeloid leukemia in Taiwan. | Cheng Z et al. | β | 2026 | β |
| Genetic loss of CHD1 regulates distinct histone post-translational modifications in the development of castration-resistant prostate cancer. | Purohit TA et al. | β | 2026 | β |
| Genetic mapping identifies Homer1 as a developmental modifier of attention. | Gershon Z et al. | β | 2026 | β |
| Genetic regulation of fatty acid content in adipose tissue. | Yan X et al. | β | 2026 | β |
| Genetic switch between unicellularity and multicellularity in marine yeasts. | Kurita G et al. | β | 2026 | β |
| Genetic transformation of rice (Oryza sativa L.) plants with the Hsp101 genomic fragment containing the coding sequence and its natural, heat-inducible promoter produced transgenics with enhanced heat tolerance. | Khungar L et al. | β | 2026 | β |
| Genetic variation shapes the chromatin accessibility landscape and transcriptional responses in mouse adipose tissue. | Mononen J et al. | β | 2026 | β |
| Genome report: de novo genome assembly of the greater Bermuda land snail, Poecilozonites bermudensis (Mollusca: Gastropoda), confirms ancestral genome duplication. | Winingear S et al. | β | 2026 | β |
| Genome sequence of the ornamental plant Digitalis purpurea reveals the molecular basis of flower color and morphology variation. | Horz JM et al. | β | 2026 | β |
| Genome-Wide Characterization of Four Gastropod Species Ionotropic Receptors Reveals Diet-Linked Evolutionary Patterns of Functional Divergence. | Wang G et al. | β | 2026 | β |
| Genome-wide identification and expression pattern analysis of pseudogenes in <i>Strobilanthes cusia</i> (Nees) Kuntze. | Lin Z et al. | β | 2026 | β |
| Genome-wide identification of HXK gene families in cucumber and watermelon: CsHXK1 and ClHXK6 play key roles in responding to multiple stresses. | Gao J et al. | β | 2026 | β |
| Genome-wide identification of the ATL gene family and their expression analysis in sweetpotato and its two diploid relatives. | Liu R et al. | β | 2026 | β |
| Genomic analysis reveals convergent signatures of selection for milk traits in sheep and goats. | Akhatayeva Z et al. | β | 2026 | β |
| Genomic and phenotypic insight into <i>Clostridioides difficile</i> RT027 isolates from China reveals diverse virulence associated with clinical symptoms. | Wang W et al. | β | 2026 | β |
| Genomic approaches to accelerate American chestnut restoration. | Westbrook JW et al. | β | 2026 | β |
| Genomic biomarkers of immunotherapy plus chemotherapy in patients with advanced NSCLC: Insights from the phase 3 ORIENT-11 study. | Liao J et al. | β | 2026 | β |
| Genomic language model mitigates chimera artifacts in nanopore direct RNA sequencing. | Li Y et al. | β | 2026 | β |
| Genomic profiling of active vitamin D colonic responses in African- and European-Americans identifies an ancestry-related regulatory variant of POLB. | Witonsky D et al. | β | 2026 | β |
| Genotype-driven variations in lncRNA expression underlie predisposition to high-grade serous ovarian cancer. | Lu M et al. | β | 2026 | β |
| Genotype-stratified adjunctive dexamethasone for tuberculous meningitis in HIV-negative adults: a randomized controlled phase 3 trial. | Donovan J et al. | β | 2026 | β |
| Germline fate determination by a single ARGONAUTE protein in <i>Ectocarpus</i>. | Bukhanets V et al. | β | 2026 | β |
| Giant chromosomes of a tiny plant-the complete telomere-to-telomere genome assembly of the simple thalloid liverwort Apopellia endiviifolia (Jungermanniopsida, Marchantiophyta). | SzabliΕska-Piernik J et al. | β | 2026 | β |
| Gli3R-mediated inhibition of hedgehog signaling alters the embryonic transcriptome in zebrafish. | Moyer AJ et al. | β | 2026 | β |
| GLIS3, a novel regulator of eicosanoid gene expression and metabolism in normal kidney and polycystic kidney disease. | Srivastava C et al. | β | 2026 | β |
| Global atlas of enhancer-promoter interactome in cotton genome revealed by profiling RNA-RNA spatial interactions. | Wen M et al. | β | 2026 | β |
| Global loss of metabolic responsiveness and elevated enzyme in leptin deficient obese mice during starvation. | Li D et al. | β | 2026 | β |
| Global RNA expression analysis of patient samples identified potential diagnostic biomarkers specific for peritoneal, ovarian and deep endometriosis. | LisΓ‘ Z et al. | β | 2026 | β |
| Global stabilization of the transcriptome in mitotic cells. | Khalizeva E et al. | β | 2026 | β |
| Glucocorticoid-dependence and independence of the circadian liver transcriptome. | Maidstone RJ et al. | β | 2026 | β |
| Glucose-dependent spatial and temporal modulation of oligodendrocyte progenitor cell proliferation via ACLY-regulated histone acetylation. | Sauma S et al. | β | 2026 | β |
| GLYATL1 is associated with metabolic and epigenetic changes and with endocrine resistance in luminal breast cancer. | MΓΌller J et al. | β | 2026 | β |
| Glycogen and lactate metabolism in mouse fetal Sertoli cells sustain the germ line. | Estermann MA et al. | β | 2026 | β |
| G-quadruplex structures are transcriptional regulatory hubs of super-enhancers. | Huang H et al. | β | 2026 | β |
| Grapevines Pretreated with Biocontrol Bacteria Have an Altered Transcriptional Response to <i>Xylella fastidiosa</i> and a Reduction in Pierce's Disease Severity. | Deyett E et al. | β | 2026 | β |
| Gut microbiome-derived propionate reprograms alveolar macrophages metabolically and regulates lung injury responses in mice. | Maruyama D et al. | β | 2026 | β |
| Gut microbiota modulation of regulatory DNA elements revealed by massively parallel functional characterization. | Zaratiana C et al. | β | 2026 | β |
| H4K16 acylations destabilize chromatin architecture and facilitate transcriptional response during metabolic perturbations. | Nitsch S et al. | β | 2026 | β |
| Haploid Mutation Mapping Identifies a Homoeologous Non-Reciprocal Translocation Linked to Reduced Fibre and Enhanced Protein in Brassica napus. | Kirzinger MW et al. | β | 2026 | β |
| Haplotype-resolved chromosome-level genome assembly of creeping bentgrass, Agrostis stolonifera. | Robbins MD et al. | β | 2026 | β |
| Haplotype-resolved genome assembly of Musella lasiocarpa reveals the critical role of structural variations in chromosomal and genome evolution. | Liu Q et al. | β | 2026 | β |
| HASTY-dependent miRNA cell-to-cell movement is required for systemic pathogen resistance in Arabidopsis. | Musso M et al. | β | 2026 | β |
| HDAC Inhibition Reshapes Splicing of Synaptic Plasticity-Related Genes and Neural Network Dynamics. | Beletskiy AP et al. | β | 2026 | β |
| Heart oedema in freshly hatched larvae of Eurasian perch is associated with multi-tissue gene dysregulation. | Debernardis R et al. | β | 2026 | β |
| Heme limitation induces LHR2, an essential gene for Leishmania pathogenesis. | Juez-Castillo G et al. | β | 2026 | β |
| Hepatocyte TIA1 constrains metabolic steatohepatitis by translationally suppressing Srebf1 mRNA in stress granules. | Liu R et al. | β | 2026 | β |
| Heritability and Transcriptional Impact of JAK3, STAT5A and STAT6 Variants in a Tyrolean Family. | Lee HK et al. | β | 2026 | β |
| Heritable changes in chromatin contacts associated with transgenerational susceptibility to diet-induced insulin dysregulation and obesity. | Chang RC et al. | β | 2026 | β |
| Heterogeneity and prognostic significance of mast cell subsets in the tumor microenvironment of prostate cancer. | Fang R et al. | β | 2026 | β |
| Heterologous prime-boost immunization of AAV-based neoantigen cancer vaccine induces anti-tumor immunity to inhibit tumor growth and relapse. | Huang CH et al. | β | 2026 | β |
| Heterozygous <i>ADAR</i> mutant mice exhibit RNA sensing-dependent neuroinflammation and phenotypes associated with Aicardi-GoutiΓ¨res syndrome. | Guo X et al. | β | 2026 | β |
| Hh and EGFR-Ras signaling promote distinct steps of tumor progression in the Drosophila follicle epithelium. | AnschΓΌtz S et al. | β | 2026 | β |
| HIF-2Ξ± expression is controlled by the progesterone receptor and regulates hCG-induced gene expression in granulosa cells during ovulation in mice. | Roennfeldt AE et al. | β | 2026 | β |
| HiFi long-read RNA sequencing enhances clinical diagnostics in rare disorders. | Jaramillo Oquendo C et al. | β | 2026 | β |
| HIF sustain a transcriptional regulatory circuit of EPAS1 expression in renal clear cell carcinoma. | Naas S et al. | β | 2026 | β |
| High-altitude hypoxia drives dentate gyrus neuronal vulnerability through an IL1Ξ±-astrocyte-SLC1A2 pathway. | Zhang Y et al. | β | 2026 | β |
| High-content screening of organoids reveals the mechanisms of human pancreas acinar specification. | Keshara R et al. | β | 2026 | β |
| High-depth RNA-seq data to investigate gene regulation mediated by phase-variable DNA methyltransferases in serogroup B <i>Neisseria meningitidis</i>. | Ascari A et al. | β | 2026 | β |
| High prevalence of tomato brown rugose fruit virus in domestic wastewater as a potential viral indicator for treatment systems. | Li L et al. | β | 2026 | β |
| High-quality genome and transcriptome analyses under temperature stress reveal heat shock protein-centric adaptive enhancement mechanisms in Taiwanese loach. | Wang G et al. | β | 2026 | β |
| High-Resolution Laser Microdissection to Investigate Transcriptional States in Formalin-Fixed Paraffin-Embedded Samples. | Di Chiaro P et al. | β | 2026 | β |
| High-throughput single-cell DNA methylation and chromatin accessibility co-profiling with SpliCOOL-seq. | Shen Q et al. | β | 2026 | β |
| High-throughput single-cell omics using semipermeable capsules. | Baronas D et al. | β | 2026 | β |
| Histone acetylation-dependent clustering of BRD2 instructs transcription dynamics. | Erdogdu NU et al. | β | 2026 | β |
| Histone methyl-transferase G9a inhibition boosts the efficacy of immune checkpoint inhibitors in experimental hepatocellular carcinoma. | Adan-Villaescusa E et al. | β | 2026 | β |
| Histone modification cross-talk and protein complex diversification confer plasticity to Polycomb repression. | Bonnet J et al. | β | 2026 | β |
| Histone variant H2BE controls activity-dependent gene expression and homeostatic scaling. | Feierman ER et al. | β | 2026 | β |
| HIV transgenic mouse monocytes display increased <i>in vivo</i> migration across the blood-brain barrier associated with increased expression of genes associated with mononuclear leukocyte movement. | Sydenstricker A et al. | β | 2026 | β |
| HLA export by melanoma cells decoys cytotoxic T cells to promote immune evasion. | Chemla Y et al. | β | 2026 | β |
| hnRNPM cooperates with BCAS2 to modulate alternative splicing during oocyte development. | Zhou S et al. | β | 2026 | β |
| Homeodomain protein Sxi1Ξ± independently controls cell-cell fusion and gene expression during sexual reproduction in Cryptococcus deneoformans. | Huang J et al. | β | 2026 | β |
| Host microenvironment in potato-Phytophthora infestans interaction revealed by single-cell spatiotemporal transcriptome. | Li Y et al. | β | 2026 | β |
| HOXA10 drives immune evasion in early lung adenocarcinoma by recruiting immunosuppressive macrophages via NF-ΞΊB/CCL2 signaling. | Ma J et al. | β | 2026 | β |
| HP1Ξ² and H3K9me3 Regulate Olfactory Receptor Choice and Transcriptional Identity. | Escamilla-Del-Arenal M et al. | β | 2026 | β |
| Human Left Ventricle circRNA-miRNA-mRNA Network Analyses Reveal a Novel Proangiogenic Role for circNPHP1 Under Ischemic Conditions. | Anwar M et al. | β | 2026 | β |
| Human milk oligosaccharides modulate inflammatory responses and lipid metabolism in a human intestinal organoid model. | Slater E et al. | β | 2026 | β |
| Human neuromuscular organoids mimic cancer-induced muscle cachexia. | Chiolerio P et al. | β | 2026 | β |
| Human neuronal differentiation under AΞ² exposure: a single-cell transcriptomic and epigenomic dataset. | Blanco-Luquin I et al. | β | 2026 | β |
| Human TET2-Mutant Clonal Hematopoiesis Expansion Is Driven by Distinct Inflammatory Signaling Responses in Stem Cells Versus Myeloid Progeny. | Huerga Encabo H et al. | β | 2026 | β |
| Hybrid genome and enzyme characterization uncover novel glycosyltransferases associated with benzylisoquinoline alkaloid chemodiversity in lotus. | Zhao H et al. | β | 2026 | β |
| Hypoxia-inducible factor 1 protects neurons from Sarm1-mediated neurodegeneration. | Meraner P et al. | β | 2026 | β |
| Hypoxia leads to reduced mito-nuclear gene expression and increased mtDNA transcriptional pausing in human cells. | Shtolz N et al. | β | 2026 | β |
| Identification and Characterization of sQTLs and eQTLs Associated with Growth Traits in Yellow-Feathered Broilers. | Chen G et al. | β | 2026 | β |
| Identification and Sequence Characterization of Semi-extractable RNAs. | Zeng C et al. | β | 2026 | β |
| Identification of ADAR1i-124: The first effective A-to-I RNA editing inhibitor with promising cancer therapeutic potential. | Minakuchi M et al. | β | 2026 | β |
| Identification of cis-regulatory elements provides insights into tissue-specific gene regulation in the sheep genome. | Xie S et al. | β | 2026 | β |
| Identification of miRNA biomarkers and development of predictive signatures for early detection and prognosis in cervical precancer and cancer. | Onyenobi E et al. | β | 2026 | β |
| Identification of novel biomarkers and therapeutic targets for type II ketosis in dairy cows through metabolomics and snRNA-Seq. | Feng X et al. | β | 2026 | β |
| Identification of novel DNA sequence motifs that modulate transcription in T cells. | Knoetze N et al. | β | 2026 | β |
| Identification of serine acetyltransferase (SAT) gene family and SAT2-mediated stress tolerance in cucumber, watermelon and melon. | Fan Z et al. | β | 2026 | β |
| Identification of small molecule inhibitors targeting FGFR through molecular docking-based screening. | Hou W et al. | β | 2026 | β |
| Identification of suicide brain transcriptomic signatures using meta-analysis of multiple cohorts. | Sokolov AV et al. | β | 2026 | β |
| Identifying and Visualizing Novel Small Open Reading Frames (sORFs) Via Ribo-Seq, Transcriptome Assembly, and ggRibo. | Wu HL et al. | β | 2026 | β |
| IDH-mutant gliomas arise from glial progenitor cells harboring the initial driver mutation. | Park JW et al. | β | 2026 | β |
| IFDlong: a model-based isoform and fusion detector for accurate annotation and quantification of long-read RNA-seq data. | Wang W et al. | β | 2026 | β |
| IFNΞ³-dependent metabolic reprogramming restrains an immature, pro-metastatic lymphatic state in melanoma. | Karakousi T et al. | β | 2026 | β |
| IFNΞ³-induced memory in human macrophages is sustained by the durability of cytokine signaling itself. | Gorin A et al. | β | 2026 | β |
| IFNΞ³ shapes macrophage inflammatory responses by STAT1 isoform-specific epigenetic and transcriptional mechanisms. | Akagha MJ et al. | β | 2026 | β |
| IgD from atypical-like memory B cells and plasma cells targets commensal and environmental antigens. | TachΓ³-PiΓ±ot R et al. | β | 2026 | β |
| IGFBP3 repression driven by inflammation links air pollution to placental and developmental defects. | Singh S et al. | β | 2026 | β |
| IL-17-mediated antifungal immunity restricts Candida albicans pathogenicity in the oral cavity. | FrΓ³is-Martins R et al. | β | 2026 | β |
| IL-18 metabolically reprograms CAR-expressing natural killer T cells and enhances their antitumor activity. | BarragΓ‘n Bravo GA et al. | β | 2026 | β |
| IL-1 delineates squalene-based adjuvant efficacy and reactogenicity in a cell-type-specific manner. | Yoshioka Y et al. | β | 2026 | β |
| IL-1Ξ² modulates inflammatory response of human bone marrow-derived MSCs and neutrophil recruitment in vitro via NF-kB-associated signaling. | Hassaan N et al. | β | 2026 | β |
| Image-based epigenetic profiling with deep learning and high-speed super-resolution microscopy. | Wang Y et al. | β | 2026 | β |
| Imagin: An Integrase-Like Gene Conserved Across Malacostracan Crustaceans Derived From a Ginger1 DNA Transposon. | Hao L et al. | β | 2026 | β |
| Immortalization and characterization of Schwann cell lines derived from NF1-associated cutaneous neurofibromas. | Li H et al. | β | 2026 | β |
| Immune checkpoint inhibitor-induced myocarditis is dependent on CD8 T cell-derived TNF and TNFR2 signaling. | Warrick KA et al. | β | 2026 | β |
| Immune gene diversity and STING1 variants in shaping cancer immunity across different genetic ancestry populations. | Hu X et al. | β | 2026 | β |
| Immune-microbiome coordination defines interferon setpoints in healthy humans. | Babdor J et al. | β | 2026 | β |
| Immune responses of Bos indicus versus Bos taurus cattle towards Bluetongue virus or Schmallenberg virus differ significantly. | DΓ©moulins T et al. | β | 2026 | β |
| Immunometabolic determinants of long-term response in leukemia patients receiving CD19 CAR T cell therapy. | Goldberg L et al. | β | 2026 | β |
| Immuno-metabolic dysregulation in type 2 diabetes is associated with altered neutrophil functional plasticity, mitochondrial dysfunction, and compromised responses in sepsis. | Ganesh K et al. | β | 2026 | β |
| Immunometabolic resistors of aging in long-lived golden spiny mice. | Kim HH et al. | β | 2026 | β |
| ImmuSeeker: deep mining of immune-related gene family signatures through lineage reconstruction. | Jiang L et al. | β | 2026 | β |
| Impact of Copper on the Physiology and Transcriptome of Methylosinus Trichosporium OB3b Grown on Either Methane or Methanol. | Peng P et al. | β | 2026 | β |
| Impaired adrenergic regulation of Kv channels underlies LC hyperactivity and early-onset sleep disruption in AD-like amyloidogenic mice. | Zhang YC et al. | β | 2026 | β |
| Impaired hepatic metabolism in Hereditary Fructose Intolerance confers fructose-independent risk for steatosis and hypertriglyceridemia. | Fulham MA et al. | β | 2026 | β |
| Improved, annotated reference genome for the highly polyphagous moth Hyphantria cunea (Fall webworm). | Maguire W et al. | β | 2026 | β |
| Incorporating genomic and transcriptomic effects in joint linear and non-linear structural models for predicting complex traits in pigs. | Vourlaki IT et al. | β | 2026 | β |
| Incorporation of genome-bound cellular proteins into HIV-1 particles regulates viral infection. | Garcia-Moreno M et al. | β | 2026 | β |
| Increased atherosclerosis and expression of inflammarafts in macrophage foam cells in AIBP-deficient mice. | Li S et al. | β | 2026 | β |
| Independent control of neurogenesis and dorsoventral patterning by NKX2-2. | Jang S et al. | β | 2026 | β |
| Individualized mRNA vaccines evoke durable T cell immunity in adjuvant TNBC. | Sahin U et al. | β | 2026 | β |
| Inducible Costimulator and Its Ligand Promote Proliferation and Migration of Tumor Cells in Cutaneous T-Cell Lymphoma. | Oka K et al. | β | 2026 | β |
| Inducible, split base editors for in vivo cancer functional genomics. | Ren D et al. | β | 2026 | β |
| Inferring Gene Networks from High-Throughput Transcriptomes. | Navarro-PayΓ‘ D et al. | β | 2026 | β |
| Inhibiting stearoyl-CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response. | Wilson A et al. | β | 2026 | β |
| Inhibition of Cxcr4 chemokine receptor signaling improves habituation learning in a zebrafish model of neurofibromatosis. | Miller AH et al. | β | 2026 | β |
| Inhibition or interference? Revisiting allelopathy through the effects of Triadica sebifera on Chrysanthemum seticuspe as a model system. | Sheng Z et al. | β | 2026 | β |
| In mouse and in vitro models, bowel preparation promotes pathogen colonization, translocation, and exacerbation of inflammation. | Clayton CA et al. | β | 2026 | β |
| Innate antiviral and immune functions associated with the HIV reservoir decay after anti-PD-1 therapy. | Talla A et al. | β | 2026 | β |
| Innate lymphoid cells activated by the cytokine TL1A link colitis to emergency granulopoiesis and the recruitment of tumor-promoting neutrophils. | Pires S et al. | β | 2026 | β |
| Innate type 2 lymphocytes trigger an inflammatory switch in alveolar macrophages. | Verwaerde S et al. | β | 2026 | β |
| Insertional activity of human Alu and L1 retrotransposons is associated with DNA repair pathways and genome instability in cancer. | Suntsova M et al. | β | 2026 | β |
| Insights into tea tree oil-mediated transcriptome modulation in Rosa hybrida. | Lopez-Jimenez J et al. | β | 2026 | β |
| In situ multi-modal characterization of pancreatic cancer reveals tumor cell identity as a defining factor of the surrounding microenvironment. | Lyubetskaya A et al. | β | 2026 | β |
| Insulin signaling engages divergent transcriptional mechanisms in neural and metabolic tissues. | Jain R et al. | β | 2026 | β |
| Integrated Analysis of Cross-Link-Ligation Data for the Detection of RNA 2D/3D Structures and Interactions In Vivo. | Lee WH et al. | β | 2026 | β |
| Integrated analysis of GWAS and molQTLs reveals cell-specific genetic variants in the porcine immune system. | Yang J et al. | β | 2026 | β |
| Integrated fetal testicular transcriptomic and epigenomic profiles during maternal nutrient restriction with dietary melatonin intervention. | El Daous H et al. | β | 2026 | β |
| Integrated Genomic and Transcriptomic Study Reveals <i>MAPK11</i> and <i>PER1</i> as Important Obesity Susceptibility Genes in a High-Risk Hispanic/Latino Population. | Kim D et al. | β | 2026 | β |
| Integrated Multi-Omic Analysis Reveals KDM5B as a Regulator of Microglial Reactivity to Immunomodulatory Stimuli. | Wohlfahrt J et al. | β | 2026 | β |
| Integrated Multi-Omics Analysis Provides Insights into the Rhizosphere Microbial Dynamics in Soybean-<i>Fusarium virguliforme</i> Interaction. | Tamrakar K et al. | β | 2026 | β |
| Integrated Single-Cell analysis Reveals molecular correlation of maternal-to-zygotic transition between human and pig embryo. | Fan J et al. | β | 2026 | β |
| Integrated transcriptomic analysis reveals metabolic remodeling and gene expression networks related to human 8-cell-stage embryo-like cells. | Paloviita P et al. | β | 2026 | β |
| Integrated transcriptomic and methylome analysis reveals retinoic acid pathway activation after decitabine treatment in EBV-associated gastric cancer. | Preston-Alp S et al. | β | 2026 | β |
| Integrated transcriptomic landscape of medulloblastoma and ependymoma reveals novel tumor subtype-specific biology. | Arora S et al. | β | 2026 | β |
| Integrated transcriptomic, translatomic, and physiological analyses reveal molecular mechanisms of chromium stress response in Chlamydomonas reinhardtii. | Zhang B et al. | β | 2026 | β |
| Integrated Volatile Metabolome and Transcriptome Analysis Provides Insights into Floral Aroma Biosynthesis in Waterlilies (<i>Nymphaea</i> L.). | Su Q et al. | β | 2026 | β |
| Integrating natural and engineered genetic variations to decode regulatory influence on blood traits. | Tardaguila M et al. | β | 2026 | β |
| Integration of bulk RNA-seq pipeline metrics for assessing low-quality samples. | Hamilton S et al. | β | 2026 | β |
| Integration of imaging-based and sequencing-based spatial omics mapping on the same tissue section via DBiTplus. | Enninful A et al. | β | 2026 | β |
| Integrative Analysis of Alternative Splicing Regulation Reveals Genetic and RBP-Mediated Mechanisms in Endometriosis Pathogenesis. | Wang Z et al. | β | 2026 | β |
| Integrative analysis of quantitative trait loci of alternative polyadenylation and GWAS highlights key regulators of milk production and immune traits in Holstein. | Tao X et al. | β | 2026 | β |
| Integrative chromosome-scale genome analysis of cupuassu provides insights into witches' broom disease resistance and expands genomic resources for Theobroma. | de Abreu VAC et al. | β | 2026 | β |
| Integrative epigenomic landscape of Alzheimer's Disease brains reveals oligodendrocyte molecular perturbations associated with tau. | Oatman SR et al. | β | 2026 | β |
| Integrative genome-wide association study and transcriptomic analysis to identify candidate genes and pathways for heterophil and lymphocyte traits in white-feathered broilers. | Zheng J et al. | β | 2026 | β |
| Integrative genomic, phylogenetic, and transcriptomic analyses reveal temperature-responsive transient receptor potential (TRP) genes in Pacific abalone Haliotis discus hannai. | Kim MA et al. | β | 2026 | β |
| Integrative genomics elucidates the evolutionary, temporal, and developmental origins of a hydrocephalus risk gene. | Hale AT et al. | β | 2026 | β |
| Integrative Molecular Analysis Reveals Determinants of Clinical Outcomes in <i>TP53</i>-Mutated Diffuse Large B-Cell Lymphoma. | Uppal M et al. | β | 2026 | β |
| Integrative Multi-Omics Analysis Reveals Molecular Signatures of Recurrence in Paired Primary and Recurrent High-Grade Serous Ovarian Cancer. | Kim MA et al. | β | 2026 | β |
| Integrative Multiomics and Drug Sensitivity Profiling Reveal Potential Biomarkers and Therapeutic Strategies in Pediatric Solid Tumors. | ElHarouni D et al. | β | 2026 | β |
| Integrative profiling of transcriptome and H3K27ac modification reveals changes associated with BCG-induced trained immunity in bovine immune cells. | Samuel BER et al. | β | 2026 | β |
| Integrative proteogenomic analysis provides molecular insights and clinical significance in gallbladder cancer. | Fu Z et al. | β | 2026 | β |
| Integrative Transcriptomic and Systems Biology Analyses Identify <i>TCB1</i> as a Calcium-Responsive Gene in <i>Cryptococcus neoformans</i>. | Tavanti AG et al. | β | 2026 | β |
| Integrins mediate symbiont-specific uptake in cnidarian larvae. | Jones VAS et al. | β | 2026 | β |
| Interleukin-4 changes the transcriptome, ECM-associated components and function of mare endometrial fibroblast: Insights from healthy and fibrotic cells. | WΓ³jtowicz A et al. | β | 2026 | β |
| Internalization of Exogenous Myelin by Oligodendroglia Promotes Lineage Progression. | PeirΓ³-Moreno C et al. | β | 2026 | β |
| Intestinal epithelial TLR5 signaling promotes barrier-supportive macrophages. | Tsai MT et al. | β | 2026 | β |
| Intracranial mesenchymal tumor, FET::CREB fusion-positive: An integrative analysis of 81 cases. | Rajan S et al. | β | 2026 | β |
| Introducing Cellular Senescence in Human Induced Pluripotent Stem Cells and Differentiated Neural Lineage for Modeling of Age-Associated Diseases. | Neherin K et al. | β | 2026 | β |
| Investigating the Mechanism of Astragalus mongholicus-Mediated Treatment of Silicosis in Mice from the Perspective of Alternative Splicing. | Zhang Y et al. | β | 2026 | β |
| Investigating the Molecular Mechanisms of the Anticancer Effects of Eugenol and Cinnamaldehyde Against Colorectal Cancer (CRC) Cells In Vitro. | Bernacchi A et al. | β | 2026 | β |
| Investigating the oncogenic role of aberrant EZH2 in hepatoblastoma. | Glaser K et al. | β | 2026 | β |
| Investigating uncharacterised genes in Saccharomyces cerevisiae using robot scientists. | BjurstrΓΆm EY et al. | β | 2026 | β |
| Investigation of gene stability in equine luteal tissue during mid-diestrus phase and early pregnancy - Research Article. | Ramsaran LN et al. | β | 2026 | β |
| In vivo dual RNA-Seq uncovers key effectors of epithelial barrier disruption by an extracellular pathogen. | Giraud-Gatineau A et al. | β | 2026 | β |
| Involvement of the FGF8/FGF Receptor Signaling Pathway in the Maintenance and Progression of Fusion-Positive Rhabdomyosarcoma. | Boudjadi S et al. | β | 2026 | β |
| iPepGen: a modular, immunopeptidogenomic analysis pipeline for discovery, verification, and prioritization of cancer peptide neoantigen candidates. | Mehta S et al. | β | 2026 | β |
| iPSC-induced multilineage liver organoids, small intestinal organoids and brain organoids sustain pangenotype hepatitis E virus propagation. | Liu F et al. | β | 2026 | β |
| IRF1 is a context-dependent homeostatic gatekeeper of basal immunity and antiviral readiness. | Zoler E et al. | β | 2026 | β |
| <i>RIN3</i> mutations impairing binding of the Alzheimer's disease-associated protein BIN1 lead to RAB5 hyperactivation and endosomal pathology. | Maaser-Hecker AK et al. | β | 2026 | β |
| Isoflurane and Surgical Stress Disrupt Fatty Acid and Carbon Metabolism, Leading to Cardiomyopathy in Aged Mice. | Yang WW et al. | β | 2026 | β |
| <i>VILMIR</i> is a <i>trans</i>-acting long noncoding RNA that enhances the host interferon response in human epithelial cells. | John K et al. | β | 2026 | β |
| Kar4 acts as a Ste12 regulator in Saccharomyces cerevisiae, promoting Ste12 binding to a specific DNA motif genome-wide. | Rogers JV et al. | β | 2026 | β |
| Ketogenic diet dampens excitatory neurotransmission by shrinking synaptic vesicle pools. | Stunault MI et al. | β | 2026 | β |
| Kidney Volume and Molecular Processes are Dynamic in ADPKD. | Tug A et al. | β | 2026 | β |
| KLHDC3 deficiency in mice reveals essential roles in development, survival, and adiposity via the DesCEND ubiquitin pathway. | Buco PAV et al. | β | 2026 | β |
| Klotho in the kidney distal convolution regulates urinary Klotho excretion and kidney calcium reabsorption, but not phosphate homeostasis. | Bourqui L et al. | β | 2026 | β |
| KORE-Map 1.1: Korean medicine omics resource extension map on transcriptome data of dyspepsia herbal medicine. | Seo EH et al. | β | 2026 | β |
| KRAS mutated lung adenocarcinoma responds to pan-ERBB and Aurora kinase inhibitors. | Uras IZ et al. | β | 2026 | β |
| Lack of MDA5 delays hematopoietic aging by modulating inflammaging and proteostasis in mice. | Bergo V et al. | β | 2026 | β |
| Lack of synergy between AR-targeted therapies and PARP inhibitors in homologous recombination-proficient prostate cancer. | Traphagen NA et al. | β | 2026 | β |
| Laminar patterning transcription factors orchestrate spatial metabolite partitioning in Capsicum fruit. | Han J et al. | β | 2026 | β |
| Lasting bone marrow defects imprinted by hyperglycemia shape the immunological characteristics of differentiated M1 and M2 macrophages. | Lee IG et al. | β | 2026 | β |
| LBR and LAP2 mediate heterochromatin tethering to the nuclear periphery to preserve genome homeostasis. | Lewis R et al. | β | 2026 | β |
| Lessons learned from manual curation of thousands of gene models in the nematode Pristionchus pacificus. | RΓΆdelsperger C et al. | β | 2026 | β |
| Leveraging Single-Cell Technologies to Advance Understanding of Myocardial Disease. | Gardner RS et al. | β | 2026 | β |
| Life History and Smoltification Shape Genomic Signatures of Thermal Tolerance in Chinook Salmon. | Metzger DCH et al. | β | 2026 | β |
| Limitations of serial cloning in mammals. | Wakayama S et al. | β | 2026 | β |
| LINC01929 mediates breast cancer immunosuppression and is an immunotherapy target. | Venkatesh J et al. | β | 2026 | β |
| LINE-1 retrotransposition modulates metabolic stress and promotes cuproptosis resistance in lung squamous cell carcinoma by disrupting mitochondrial membrane homeostasis. | Zhang R et al. | β | 2026 | β |
| Lipid Droplet-Driven Ribosome Collisions Trigger ZAKΞ±-p38 Signaling to Accelerate Testicular Aging. | Xu Y et al. | β | 2026 | β |
| Lipid metabolism transcriptomic signature of defective erythropoiesis in Diamond Blackfan anemia syndrome. | Deng K et al. | β | 2026 | β |
| Liquid Crystal Monomers Released from LCD Displays Accumulate in Endangered Marine Cetaceans Triggering Health Concerns. | Tao D et al. | β | 2026 | β |
| Liver-specific delivery of MDM2 antisense oligonucleotides counteracts diet-induced metabolic-dysfunction-associated steatotic liver diseases. | Hoque MM et al. | β | 2026 | β |
| LncRNA-splicing factor condensates regulate hypoxia-responsive pre-mRNA processing near nuclear speckles. | Song YJ et al. | β | 2026 | β |
| Long COVID involves activation of proinflammatory and immune exhaustion pathways. | Aid M et al. | β | 2026 | β |
| Longitudinal Peripheral Blood Transcriptomics Reveal Novel Signatures During Cardiac Allograft Rejection. | Ghazal R et al. | β | 2026 | β |
| Long-Read Sequencing Reveals Cell- and State-Specific Alternative Splicing in 293T and A549 Cell Transcriptomes. | Li X et al. | β | 2026 | β |
| Long-term culture of germ-free zebrafish using gamma-irradiated feeds. | Okyere L et al. | β | 2026 | β |
| Loss-of-function allele of the soybean flowering/maturation gene TOF11 increases free amino acid content at the edamame stage and improves eating quality. | Shioya N et al. | β | 2026 | β |
| Loss of SETDB1-mediated H3K9me3 in human neural progenitor cells leads to transcriptional activation of L1 retrotransposons. | Karlsson O et al. | β | 2026 | β |
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| Low, non-psychedelic doses of psilocybin as a novel treatment for MASLD, obesity and type 2 diabetes via 5-HT2B receptor-dependent mechanisms. | Colognesi M et al. | β | 2026 | β |
| <i>ATG</i> gene duplication in vertebrates: evolutionary divergence and its functional implications. | Zhang S et al. | β | 2026 | β |
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| <i>MALAT1</i> regulates human macrophage metabolism by interacting with HADHB. | Liu Y et al. | β | 2026 | β |
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| m6AConquer: a consistently quantified and orthogonally validated database for the N6-methyladenosine (m6A) epitranscriptome. | Zhao X et al. | β | 2026 | β |
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| Medicinal cannabis plant extract (NTI164) modifies epigenetic, ribosomal, and immune pathways in paediatric acute-onset neuropsychiatric syndrome. | Keating BA et al. | β | 2026 | β |
| Mediterranean Versus Western Diet Effects on Obesity Phenotypes and Adipose Tissue Transcriptional Profiles in Female Monkeys. | Abusheikha AJ et al. | β | 2026 | β |
| Membrane remodelling mediates lipopeptide-induced immunity in Arabidopsis. | Gilliard G et al. | β | 2026 | β |
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| Mesenchymal stromal cell therapy restores intestinal integrity and attentuates inflammation in a preterm piglet model of necrotizing enterocolitis. | Lee J et al. | β | 2026 | β |
| Mesothelin promotes acute myeloid leukemia progression through LYN-dependent signaling. | Faust JR et al. | β | 2026 | β |
| Met32 governs transcriptional control of sulfur metabolic flexibility and resistance to reactive sulfur species in the human fungal pathogen <i>Candida albicans</i>. | Menon ACT et al. | β | 2026 | β |
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| Metabolic reprogramming regulates histone lactylation during zebrafish caudal fin regeneration. | Borbinha J et al. | β | 2026 | β |
| Metabolic resistance of the tiger mosquito to pyrethroid insecticides in La RΓ©union Island likely results from local adaptation. | Bacot T et al. | β | 2026 | β |
| Metabolome and Transcriptome Profiling of Chicory Roots Provide Insights Into Laticifer Development and Specialized Metabolism. | Vahabi K et al. | β | 2026 | β |
| Metformin inhibits nuclear egress of chromatin fragments in senescence and aging. | Kumazawa T et al. | β | 2026 | β |
| Methionine and choline deficiency rewires transcriptional programs to recapitulate molecular features of human MASH. | You W et al. | β | 2026 | β |
| METTL14-mediated RNA m<sup>6</sup>A modifications of TET1 and TET2 in duck myoblast differentiation. | Liu J et al. | β | 2026 | β |
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| METTL3-based epitranscriptomic editing screening identifies functional m<sup>6</sup>A sites in cancers. | Xu X et al. | β | 2026 | β |
| MEX3A Modulates PPARΞ³ Pathway Activity and Colorectal Cancer Growth. | Silva AR et al. | β | 2026 | β |
| Microbiome by transcriptome interactions triggered by a switch to an alternative diet in Nellore cattle. | Fernandes AC et al. | β | 2026 | β |
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| Microglia cause HIV-induced transcriptional and metabolic changes in human neural organoids. | Capendale PE et al. | β | 2026 | β |
| Microglia-independent rAAV-induced inflammation causes persistent ocular immune dysregulation rescued by S1P receptor modulation. | Langer PM et al. | β | 2026 | β |
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| Mining Differentially Expressed Genes in the Marine Free-Living Flatworm <i>Macrostomum lignano</i> Under Aneuploidy-Driven Ploidy Changes. | Zadesenets KS et al. | β | 2026 | β |
| miR-302 regulates pancreatic progenitor pool and pancreatic size. | Yang ZZ et al. | β | 2026 | β |
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| Mitochondrial remodeling in skeletal muscle underlies exercise-induced reversal of age-associated functional decline in mice and humans. | GarcΓa-DomΓnguez E et al. | β | 2026 | β |
| Mitochondrial transfer from immune to tumor cells enables lymph node metastasis. | Terasaki A et al. | β | 2026 | β |
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| M<sup>5</sup>C-driven stabilization of SERPINB5 promotes cervical cancer progression and chemotherapy resistance. | Liu J et al. | β | 2026 | β |
| m<sup>6</sup>A reader Ythdf proteins control retrotransposon B2 repeat expression and safeguard early embryo development. | Su R et al. | β | 2026 | β |
| Modeling human enterovirus A71 infection using an intestinal microphysiological system. | Futatsusako H et al. | β | 2026 | β |
| Modest rescue of RBFOX1 splicing function attenuates Huntington's disease features. | Lozano-MuΓ±oz D et al. | β | 2026 | β |
| Modulating alternative splicing of <i>MECP2</i> is a potential therapeutic strategy for Rett syndrome. | Tirumala HP et al. | β | 2026 | β |
| Modulation of striatal cAMP levels: A key pathway in the treatment of hyperkinetic movement disorders. | Yuan R et al. | β | 2026 | β |
| Modulation of the leaf transcriptome of Quercus robur by specialist and generalist herbivorous insects. | Mader M et al. | β | 2026 | β |
| Molecular and cellular processes disrupted in the early postnatal Down syndrome prefrontal cortex. | Risgaard RD et al. | β | 2026 | β |
| Molecular and Clinical Analyses of Gene Fusions Identify Therapeutic Targets in Paired Primary and Metastatic Breast Cancer from the AURORA Program (BIG 14-01). | Biagioni C et al. | β | 2026 | β |
| Molecular genotype-phenotype correlation in ACTB- and ACTG1-related non-muscle actinopathies. | Di Donato N et al. | β | 2026 | β |
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| Molecular QTL are enriched for structural variants in a cattle long-read cohort. | Mapel XM et al. | β | 2026 | β |
| Molecular Responses to Temperature Changes Across Timescales in the Madagascar Ground Gecko (Paroedura picta). | Sakamoto F et al. | β | 2026 | β |
| Molecular risk markers define risk of relapse in myeloid leukemia of Down syndrome beyond measurable residual disease. | Berman JN et al. | β | 2026 | β |
| Molecular Signatures of Peripheral and Central Dental Pulp Subpopulations in Response to Streptococcus mutans: A Bulk RNA-Seq Analysis. | Pohl S et al. | β | 2026 | β |
| Monkeypox virus replication and host response in vaginal and ectocervical epithelial cells. | Mariotti D et al. | β | 2026 | β |
| Monocyte-derived IL-10 drives sex differences in pain duration. | Sim J et al. | β | 2026 | β |
| Mosaic gastruloids reveal a temporal restriction for developmental cell competition. | Frenster JD et al. | β | 2026 | β |
| Mouse Trophoblast Stem Cells Are Deficient in TNFΞ±-Activated NFΞΊB Signaling Pathway and Inflammatory Response. | Bae Y et al. | β | 2026 | β |
| MPXV RNA-seq data provide evidence for protection of viral transcripts from APOBEC3 editing. | Lyskova AO et al. | β | 2026 | β |
| Multidimensional immune profiling uncovers biphasic peripheral T-cell dynamics after chemoradiation in patients with locally advanced head and neck cancer. | Lecoester B et al. | β | 2026 | β |
| Multidimensional mapping of stimulation-responsive regulatory elements and candidate causal variants in T cell activation. | Wang Z et al. | β | 2026 | β |
| Multidimensional transcriptome dataset for systematic evaluation of Jakyakgamcho-tang-induced cell signatures. | Baek SJ et al. | β | 2026 | β |
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| Multi-layered molecular profiling informs the diagnosis and targeted therapy of desmoplastic small round cell tumor. | Renner M et al. | β | 2026 | β |
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| Multimodal profiling of pancreatic cancer reveals a TIMP-1-dominated secretory profile determining pro-tumor immunoinstruction in human cancers. | FrΓ€drich J et al. | β | 2026 | β |
| Multimodal survival analysis of glioblastoma using whole-slide histopathology, gene expression, clinical variables and language-model-derived mutation features. | Wang T et al. | β | 2026 | β |
| Multiomic analysis of ART-interruption cohorts identifies cell-extrinsic and -intrinsic mechanisms driving lymphocyte-mediated control of HIV rebound. | Ma T et al. | β | 2026 | β |
| Multi-omic analysis of human PHACTR1 signaling networks. | Wolhuter K et al. | β | 2026 | β |
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| Multi-omics analysis of pediatric short bowel syndrome induced intestinal failure and associated liver disease: Association with gut microbial deviations. | Mutanen A et al. | β | 2026 | β |
| Multi-omics analysis reveals ER stress as a main feature in two endothelial cell models of N-linked congenital disorders of glycosylation. | Driesen K et al. | β | 2026 | β |
| Multiomics and deep learning dissect regulatory syntax in human development. | Liu BB et al. | β | 2026 | β |
| Multi-omics identifies oxidative stress, prothrombotic pathways, and lactoperoxidase variants as key factors in COVID-19 severity. | Cappadona C et al. | β | 2026 | β |
| Multi-omics reveals key molecular and cellular features of advanced small cell lung cancers associated with distinct therapeutic opportunities. | Nones K et al. | β | 2026 | β |
| Multiorgan Molecular Landscape of Severe COVID-19 Revealed by Consensus Gene Signatures and RAB8B Targeting. | Avila JP et al. | β | 2026 | β |
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| Multi-tissue transcriptomic aging atlas reveals predictive aging biomarkers in the killifish. | Costa EK et al. | β | 2026 | β |
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| Mutant ribosomal protein RPS15 drives B cell malignancy through oxidative stress and genomic instability. | Gutierrez C et al. | β | 2026 | β |
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| MYB100-GA20ox3 Module Promotes Flowering by Activating Gibberellin Pathway in Brassica napus. | Chang W et al. | β | 2026 | β |
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| MYC-bound enhancer RNAs in cis regulate gene transcription and tumorigenesis. | Li S et al. | β | 2026 | β |
| Myelin antigen capture in the CNS by B cells expressing EBV latent membrane protein 1 leads to demyelinating lesion formation. | Kim H et al. | β | 2026 | β |
| Myeloid immune checkpoint blockade overcomes antibiotic resistance in bone infection by enhancing efferocytosis and suppressing MSC PANoptosis. | Qu Y et al. | β | 2026 | β |
| Myoglobin Affects Tissue-Specific Transcriptome, Heart Regeneration and Whole Animal Metabolic Rates. | Hejlesen R et al. | β | 2026 | β |
| MYRF controls mesothelium specification, signaling, and plasticity in lung development. | Luna G et al. | β | 2026 | β |
| NAD<sup>+</sup> controls circadian rhythmicity during cardiac aging. | Carpenter BJ et al. | β | 2026 | β |
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| Necroptosis in both tumour and stromal compartments determines responsiveness to immunogenic cell death-based immunotherapy. | Fernando W et al. | β | 2026 | β |
| Neighborhood opportunity and cellular senescence in a national sample of U.S. adults. | Rodrigues M et al. | β | 2026 | β |
| Neoadjuvant ipilimumab plus nivolumab in melanoma: 5-year survival and biomarker analysis from the phase 2 PRADO-trial. | Hoeijmakers LL et al. | β | 2026 | β |
| Neoadjuvant modified FOLFIRINOX plus nivolumab in borderline-resectable pancreatic ductal adenocarcinoma: a pilot phase 1 trial. | Wainberg ZA et al. | β | 2026 | β |
| Neoadjuvant palbociclib and endocrine therapy versus chemotherapy in ERβ+β/HER2- breast cancer: a randomized phase II trial. | Matikas A et al. | β | 2026 | β |
| NeoPrecis: enhancing immunotherapy response prediction through integration of qualified immunogenicity and clonality-aware neoantigen landscapes. | Lee KH et al. | β | 2026 | β |
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| Neural crest cell-derived DKK1 and NEDD4 modulate Wnt signalling in theΒ second heart field to orchestrate outflow tract development. | Wiszniak S et al. | β | 2026 | β |
| Neurofibromin 1 (<i>NF1</i>) Splicing Mutation c.61-2A>G: From Aberrant mRNA Processing to Therapeutic Implications In Silico. | Blazyte A et al. | β | 2026 | β |
| Neuroimmune regulation of inflammation: RNA-Seq study of somatostatin-6 effects in gilthead seabream (Sparus aurata) skin and brain. | Campos-SΓ‘nchez JC et al. | β | 2026 | β |
| Neutralizing hepatic apolipoprotein E enhances aged bone fracture healing. | Huang M et al. | β | 2026 | β |
| Newly Identified Transcriptomic Biomarkers and Gene Signature of Pathological Complete Response to Induction Chemoimmunotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma. | Zhou JG et al. | β | 2026 | β |
| NF-ΞΊB and STAT3 signaling uniquely stratify survival in female glioblastoma patients. | Wong JP et al. | β | 2026 | β |
| Nintedanib Lacks Efficacy in a Spirometry-Confirmed and Bleomycin-Induced Mouse Model of Idiopathic Pulmonary Fibrosis. | Bousamaki J et al. | β | 2026 | β |
| NNMT inhibition counteracts tubular senescence and fibrosis in early stages of chronic kidney disease. | Chanvillard L et al. | β | 2026 | β |
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| Nonsense-mediated mRNA decay safeguards telomeres in pluripotent stem cells. | Markiewicz-Potoczny M et al. | β | 2026 | β |
| Novel Cell Cycle Inhibitors Decrease Primary and Metastatic Breast Cancer Growth In Vivo. | Maqbool MS et al. | β | 2026 | β |
| Novel nucleoside analogs exhibit potent intracellular and <i>in vivo</i> activities against <i>Mycobacterium avium</i>. | Park H-S et al. | β | 2026 | β |
| Novel Syngeneic Cell Lines for Studying High-Risk BRAFV600E-Driven Colorectal Cancer In Vivo. | Traichel J et al. | β | 2026 | β |
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| NRF2-COX2-PGE 2 axis drives immune cold tumors and predicts resistance to combination immunotherapy in hepatocellular carcinoma. | Yamamoto S et al. | β | 2026 | β |
| NRF2 deficit prevents pathologic Tau seeding and spreading in an induced tauopathy mouse model. | LΓ³pez-Sampere Y et al. | β | 2026 | β |
| NRF2 upregulation by CDDO-Me protects AC16 human cardiomyocytes against doxorubicin-induced toxicity. | Roberts JA et al. | β | 2026 | β |
| NSMF modulates replication stress to facilitate colorectal cancer progression. | Shin KJ et al. | β | 2026 | β |
| Nuclear import of malaria RNA rewires splicing in host immune cells. | Abou Karam P et al. | β | 2026 | β |
| Oculocutaneous albinism variants in 28 consanguineous families and functional classification of a pathogenic deep intron variant in TYR. | Farooq M et al. | β | 2026 | β |
| Omics-aided design genome editing strategy for challenging human immortalized cell models. | Mendoza-Garcia P et al. | β | 2026 | β |
| omnideconv: a unifying framework for using and benchmarking single-cell-informed deconvolution of bulk RNA-seq data. | Dietrich A et al. | β | 2026 | β |
| OncoDB 2.0: a comprehensive platform for integrated pan-cancer omics analysis. | Cho M et al. | β | 2026 | β |
| Oncogenic epigenetic factor EP300 is a potential therapeutic target for bladder carcinoma. | Zhang Q et al. | β | 2026 | β |
| Optics-free spatial genomics for mapping mammalian brain aging by IRISeq. | Abdulraouf A et al. | β | 2026 | β |
| Optimizing Chloride Fertilization Enhances Kiwifruit (<i>Actinidia</i> spp.) Photosynthetic, Carbon-Nitrogen Metabolic, and Antioxidant Physiological Characteristics. | Fan X et al. | β | 2026 | β |
| Optimizing muscle satellite cell sources for cultured meat: anatomical origin influences cellular properties and quality attributes. | Lee J et al. | β | 2026 | β |
| Optimizing Single-Cell Long-Read Sequencing for Enhanced Isoform Detection in Pancreatic Islets. | Hansen MS et al. | β | 2026 | β |
| OsCLSY4 modulates epigenomic patterns and grain size in rice. | Zhang R et al. | β | 2026 | β |
| OTX2 inhibits human pluripotent stem cell reprogramming toward 8-cell-like and morula-like states. | Kong X et al. | β | 2026 | β |
| Overexpression of the maize 9-lipoxygenase gene LOX4 confers resistance to Fusarium verticillioides via the oxylipin- and jasmonic acid-mediated pathways. | Ottaviani L et al. | β | 2026 | β |
| P2X7 receptor or TNAP genetic blockade prevents the reduction of neuronal CTCF detected in tauopathy. | Aivar P et al. | β | 2026 | β |
| p38 MAPK orchestrates cross-tissue potassium homeostasis for survival. | Huang R et al. | β | 2026 | β |
| p53 increases phospholipid headgroup scavenging in senescence. | Yashinskie JJ et al. | β | 2026 | β |
| Pain Hypersensitivity in a Mouse Model of Marfan Syndrome. | Kordikowski R et al. | β | 2026 | β |
| Pan-cancer inference and validation of hypermorphic, hypomorphic and neomorphic mutations. | Tagore S et al. | β | 2026 | β |
| Paneth cell SIRT1 deficiency increases intestinal stress resistance by modulating the gut microbiota. | Garcia-Peterson LM et al. | β | 2026 | β |
| Pangenome analysis of nine soybean cyst nematode genomes reveals hidden variation contributing to diversity and adaptation. | Santos LBD et al. | β | 2026 | β |
| Pangenome analysis reveals families of ubiquitin-ligase adaptors as key genomic divergence drivers that lead to hybrid incompatibility. | Xie D et al. | β | 2026 | β |
| Pangenomic Approach for the Identification and Functional Characterization of Active GASA Antimicrobial Genes in Citrus Rootstocks for Resistance Breeding Against Bacterial Pathogens. | Bekier FN et al. | β | 2026 | β |
| PARANOiD: Pipeline for Automated Read ANalysis of iCLIP Data. | Barth P et al. | β | 2026 | β |
| Parathyroid Hormone Contributes to Pulmonary Hypertension in Hypoxic Conditions. | Joki Y et al. | β | 2026 | β |
| PARP1 suppression drives ROS resistance in aneuploid cancer cells. | Cheng P et al. | β | 2026 | β |
| Partial embryo loss caused by disruption of the placental hormone CTRP6 coincides with dNK cell abnormalities during pregnancy. | Fan H et al. | β | 2026 | β |
| Pathogenetic mechanisms of muscle-specific ribosomes in dilated cardiomyopathy. | Murphy MR et al. | β | 2026 | β |
| Pathway-specific canalization and plasticity of gene expression during <i>C</i>. <i>elegans</i> dauer development. | Corchado JC et al. | β | 2026 | β |
| Patient-derived kidney organoids recapitulate ADPKD and facilitate the identification of Rho pathway inhibitors as candidate therapeutics. | Guo L et al. | β | 2026 | β |
| Patient-derived lung organoids from bronchoalveolar lavage capture epithelial heterogeneity and disease biology in bronchopulmonary dysplasia. | Sonti S et al. | β | 2026 | β |
| Pattern separation memory requires Cerebellin 4 - Neogenin 1 signaling at dentate gyrus synapses. | Liakath-Ali K et al. | β | 2026 | β |
| PCB 153 Modulates Genes Involved in Proteasome and Neurodegeneration-Related Pathways in Differentiated SH-SY5Y Cells: A Transcriptomic Study. | Minuti A et al. | β | 2026 | β |
| PCBP1 regulates alternative splicing of AARS2 in congenital cardiomyopathy. | Lu YW et al. | β | 2026 | β |
| PCLIPtools: a robust framework for identifying RNA-protein interaction sites from PAR-CLIP experiments. | Polash AH et al. | β | 2026 | β |
| Percentage of CD56<sup>+</sup> monocytes at neutrophil engraftment is associated with the incidence of acute graft-versus-host disease. | Hashimoto K et al. | β | 2026 | β |
| Performance evaluation and methods comparison of transcriptomic-based approaches for the characterization of wastewater treatment effluent. | Biales AD et al. | β | 2026 | β |
| Pericytes are organ-specific regulators of tissue morphogenesis. | Rasouli SJ et al. | β | 2026 | β |
| Perinatal BPAF Exposure Reprograms Offspring's Immune-Metabolic Axis: A Multi-Omics Investigation of Intergenerational Hepatotoxicity. | Bai S et al. | β | 2026 | β |
| Perinatal infection elicits clonally restricted T follicular helper cell responses that drive antibody-mediated viral control. | Martin K et al. | β | 2026 | β |
| Peripheral immune-inducer dendritic cells drive early-life allergic inflammation. | Xing Y et al. | β | 2026 | β |
| Persistent viral control status is associated with enhanced innate immune responses in people with HIV-1. | C Dos Santos J et al. | β | 2026 | β |
| PFAS Alter Thyroid Histology and Cellular Signaling <i>In Vitro</i> and <i>In Vivo</i>. | Hartmann HA et al. | β | 2026 | β |
| PFOS and PFOA exposure induces liver injury and sex-dependent immune effects in C57BL/6 mice. | Blais A et al. | β | 2026 | β |
| Pharmacological transglutaminase 2 inhibition enhances temozolomide response in patient-derived glioblastoma tumorspheres. | Hong JP et al. | β | 2026 | β |
| Phase separation of Rht8-derived RNHL1 integrates ethylene and gibberellin signaling to regulate wheat internode elongation. | Dong C et al. | β | 2026 | β |
| PHIP suppresses NuRD to enable the growth of SWI/SNF-mutant cancers. | Malone HA et al. | β | 2026 | β |
| Photorespiration is linked to DNA methylation by formate as a one-carbon source. | Hankofer V et al. | β | 2026 | β |
| Phylotranscriptomics and genome size evolution in Leucaena (Fabaceae): Paleotetraploid genomic stability overshadows diploidization and environmental effects. | Abair A et al. | β | 2026 | β |
| Physiochemical and transcriptional reprogramming of mild salinity mediated modulation of Steviol Glycoside biosynthesis in Stevia rebaudiana Bertoni. | Sharma S et al. | β | 2026 | β |
| Physiological Changes and Transposition of Insertion Sequences in the <i>dps</i>-Double-Knockout Mutant of <i>Deinococcus geothermalis</i>. | Park Y et al. | β | 2026 | β |
| Pichia pastoris RNA-Sequencing and Data Analysis. | Krappinger JC et al. | β | 2026 | β |
| PIWIL1 activates the R2TP-TELO2-mTORC1 axis independently of piRNA to promote TOP mRNA translation in gastric cancer. | Fan T et al. | β | 2026 | β |
| PKM2-DNMT3A-SMAD2 Axis Regulates Cell Proliferation via Histone Lactylation in Breast Cancer. | Sabu A et al. | β | 2026 | β |
| PlantscRNAdb 4.0: Improved marker identification and annotation under a cell-type uniformity for plants. | Zheng D et al. | β | 2026 | β |
| Plasma extracellular vesicle sampling from glioblastoma demonstrates a small RNA signature indicative of disease and identifies lncRNA <i>RPPH1</i> as a biomarker. | Ho Han J et al. | β | 2026 | β |
| Platelet Secretome Drives Mitogenic and TGF-Ξ² Responses in Gingival Fibroblasts. | Panahipour L et al. | β | 2026 | β |
| PolyAseqTrap: a universal tool for genome-wide identification and quantification of polyadenylation sites from different 3' end sequencing data. | Ye W et al. | β | 2026 | β |
| Polychlorinated biphenyl 153 alters the intestinal epithelial cell transcriptome. | Ham H et al. | β | 2026 | β |
| Polydopamine-Based Antioxidant Countermeasures Against Spaceflight-Induced Neurodegeneration. | Carmignani A et al. | β | 2026 | β |
| Polysome Profiling: A Method for Global and Targeted Analysis of mRNA Translation. | Fabbri L et al. | β | 2026 | β |
| Polystyrene nanoplastics modulate neurite length in a size-specific manner. | GΓ³rovΓ‘ V et al. | β | 2026 | β |
| Population-specific transcriptomics of Pacific oyster after exposure to a highly pathogenic, globally distributed virus. | Calla B et al. | β | 2026 | β |
| Position effect variegation (PEV) as an aging clock: visualization of age-dependent loss of heterochromatin and longevity associated with enhanced heterochromatin. | Tedeschi S et al. | β | 2026 | β |
| Post-thaw storage of sperm as a tool towards revealing paternal-effect-associated genes in Eurasian perch, Perca fluviatilis. | Panda A et al. | β | 2026 | β |
| Posttranscriptional reprogramming controls MASLD progression through chronic ER stress adaptation. | Belloc E et al. | β | 2026 | β |
| Post traumatic response of coelomocytes in the common sea star Echinastersepositus. | Pagliara P et al. | β | 2026 | β |
| Prdm16 Amplifies Notch Signaling and Suppresses Venous Lineage Specification to Prevent Arteriovenous Malformations During Vascular Development. | Van Wauwe J et al. | β | 2026 | β |
| Precise, minimally evolved adenine base editors generated through mutation reversion analysis. | Evanoff M et al. | β | 2026 | β |
| Preclinical Evaluation of the Efficacy of the Cyclin-Dependent Kinase Inhibitor Ribociclib in Combination with Letrozole against Patient-Derived Glioblastoma Cells. | Gadgil SN et al. | β | 2026 | β |
| Precursors of sea star wasting: immune and microbial disruption during initial disease outbreak in southeast Alaska. | McCracken AR et al. | β | 2026 | β |
| Predicting trajectories of illness using RNA velocity of whole blood. | Dunican C et al. | β | 2026 | β |
| Prenatal exposure to particulate matter impairs offspring behavior via hippocampal NMDA receptor reduction: an in vivo and ex vivo study. | Eom Y et al. | β | 2026 | β |
| Preterm Birth Increases Susceptibility to Hyperglycemia-Induced Kidney Injury With Sex-Specific Differences in Structural and Molecular Responses. | Dailey RK et al. | β | 2026 | β |
| Prevention of Cholestatic Liver Disease Through BCL6-FXR Enterohepatic Crosstalk. | Fruzyna E et al. | β | 2026 | β |
| Priestia megaterium reduces hydrogen sulfide level in swine manure potentially through an assimilatory mechanism and microbiota modulation. | Kim SH et al. | β | 2026 | β |
| Priming plants to withstand drought tolerance: Systemic responses of tomato plants mediated by a root-residing fungal endophyte. | Feka M et al. | β | 2026 | β |
| Prior high fiber intake impinges on the cellular responses of mesenteric adipose and intestinal tissues to subsequent high fat feeding. | Peng Z et al. | β | 2026 | β |
| Probiotic Lactobacillus rhamnosus mitigates PBC-like features in Mcpip1-deficient mice via modulation of gut-liver crosstalk. | Trzos K et al. | β | 2026 | β |
| Profiling active RNA polymerase II transcription start sites from total RNA by capped small RNA sequencing (csRNA-seq). | Meyer MK et al. | β | 2026 | β |
| Profiling the epigenomic landscape of late embryonic and adult mouse hind limb muscles. | Queeno SR et al. | β | 2026 | β |
| Profiling the host defense responses against <i>Candida auris</i> in a reliable <i>Drosophila melanogaster</i> infection model. | Li J et al. | β | 2026 | β |
| Progress and challenges in profiling protein-RNA and protein-associated RNA-RNA interactions. | Song Z et al. | β | 2026 | β |
| Proinflammatory CD20<sup>+</sup>CD3<sup>+</sup> T cells as a potential driver of macrophage reprogramming in rheumatoid arthritis. | Jiang S et al. | β | 2026 | β |
| Prolonged duration induces divergent transcriptomic responses to manganese, distinct from concentration effects, in an SH-SY5Y neurotoxicity model. | Tang X et al. | β | 2026 | β |
| Prostate Cancer: Dissecting Novel Immunosuppressive Mechanisms Through Context-Specific Transcriptomic Programs and MDSC Cells. | Reyes Martinez P et al. | β | 2026 | β |
| Proteostasis failure and mitochondrial dysfunction contribute to chromosomal instability-induced microcephaly. | GonzΓ‘lez-Blanco A et al. | β | 2026 | β |
| Proteostasis sustains T cell differentiation potential and tumor-infiltrating lymphocyte function. | Scharping NE et al. | β | 2026 | β |
| Protocols to evaluate mutant specificity of an oncogene-targeting siRNA using orthogonal in vitro and in vivo approaches. | Stanland LJ et al. | β | 2026 | β |
| PTBP1 supports mouse spermatogenesis by facilitating cytoskeletal organization through the mTORC2-PKCΞ± pathway in Sertoli cells. | Ozawa M et al. | β | 2026 | β |
| PTPN11-related Noonan syndrome predisposes to multifocal low-grade CNS tumors harboring FGFR1 variants. | Kohanbash G et al. | β | 2026 | β |
| PTUPB improves cognitive function in Alzheimer's disease associated with enhancing cerebral vascular myogenic response and attenuating vascular remodeling. | Morgan GC et al. | β | 2026 | β |
| Pulmonary surfactant protein D reduces lung cancer progression associated with decreased IL-4/STAT6 signaling. | Mohammadi A et al. | β | 2026 | β |
| Purification and Transcriptomic Characterization of Hypertrophied Hepatic Stellate Cells From CDAHFD Mouse Liver. | Heckmann M et al. | β | 2026 | β |
| Quantification and transcriptome profiling reveal abundant, dynamic and translatable dephospho-CoA-capped RNAs. | Hu H et al. | β | 2026 | β |
| Quantitatively controlled and measured-traumatic brain injury impairs adult neurogenesis and alters neuropathological signatures in mice. | Yang S et al. | β | 2026 | β |
| Quemliclustat and chemotherapy with or without zimberelimab in metastatic pancreatic adenocarcinoma: a randomized phase 1 trial. | Wainberg ZA et al. | β | 2026 | β |
| RABEP1 regulates neutrophil migration via endosomal recycling and actin polymerization. | Kim DH et al. | β | 2026 | β |
| Radiotherapy plus neoadjuvant and concomitant IL-13RΞ±2-directed immunotoxin therapy for diffuse intrinsic pontine glioma. | Rechberger JS et al. | β | 2026 | β |
| Radiotherapy synergizes with an inducible AAV-based immunotherapy platform to program local and systemic antitumor immunity. | Marco S et al. | β | 2026 | β |
| Rapamycin Reverses the Hepatic Response to Diet-Induced Metabolic Stress That Is Amplified by Aging. | Havas A et al. | β | 2026 | β |
| Rapid Decentralized Prostate Cancer Risk Stratification by Portable Liquid Biopsy Analysis within a Clinical Biosensor Validation Framework. | Koo KM et al. | β | 2026 | β |
| Rapid disassembly and Piwi-independent reassembly of <i>Drosophila</i> piRNA cluster heterochromatin following acute heat shock. | Rice NP et al. | β | 2026 | β |
| Rapid mid-Cretaceous diversification of squid and cuttlefish preceded radiation into coastal niches. | Sanchez G et al. | β | 2026 | β |
| Rare Cancer Explorer 1.0Β (RaCE 1.0): a dedicated database and analytical platform focused on rare cancers. | Chen Y et al. | β | 2026 | β |
| RAS/MEK/PI3K pathway inhibition augments response to CD40 agonism by targeting CD11b<sup>+</sup> Bregs thereby overcoming melanoma PD1-resistance. | Yan C et al. | β | 2026 | β |
| Ready for battle: histone modifications shape rice intergenerational memory to protect against nematode attack. | Atighi MR et al. | β | 2026 | β |
| Rebalancing NTRK2 isoforms promotes vascular regeneration in bronchopulmonary dysplasia. | Zhang Y et al. | β | 2026 | β |
| Recapitulating patient-to-patient colorectal cancer tumor heterogeneity using patient-derived xenograft cells in an engineered tissue model. | Hassani I et al. | β | 2026 | β |
| Reconstitution of sex determination and the testicular niche using mouse pluripotent stem cells. | Yoshino T et al. | β | 2026 | β |
| Reconstruction of T cell infiltration in an osteosarcoma PDX-organoid interactive biobank for personalized immunotherapy. | Sun W et al. | β | 2026 | β |
| Reduced cortico-muscular output is associated with intrinsic hypoexcitability and reduced persistent inward currents in motor cortex neurons of TDP-43<sup>Q331K</sup> ALS mice. | Viteri JA et al. | β | 2026 | β |
| Reduced cyclin D3 expression in erythroid cells protects against malaria. | Marini MG et al. | β | 2026 | β |
| Reduced LOXL3 Expression Disrupts Microtubule Acetylation and Drives TP53-Dependent Cell Fate in Glioblastoma. | Laurentino TS et al. | β | 2026 | β |
| Reduced osteogenic factors and early osteoblast senescence in SOD1(G93A) ALS mouse model. | Γzkan B et al. | β | 2026 | β |
| Reduction of RAD23A extends lifespan and mitigates pathology in a mouse model of TDP-43 proteinopathy. | Guo X et al. | β | 2026 | β |
| Reference-free discovery with barcoded single-cell sequencing. | Dehghannasiri R et al. | β | 2026 | β |
| Regional and Cell-Type-Specific Activation of YAP/TAZ Underlies Glial Responses in LPS-Induced Neuroinflammation. | Kwon TW et al. | β | 2026 | β |
| Regulation of tRNA expression during the social cycle of the amoeba Dictyostelium discoideum. | Valdivia DI et al. | β | 2026 | β |
| Reliable detection of Host-Microbe Signatures in cancer using PRISM. | Ghaddar B et al. | β | 2026 | β |
| Replicate avian hybrid zones reveal the progression of genetic and trait introgression through time. | CastaΓ±o MI et al. | β | 2026 | β |
| Replication stress-inducing ELF3 upregulation promotes BRCA1-deficient breast tumorigenesis in luminal progenitors. | Zhou J et al. | β | 2026 | β |
| Repurposing public sarcoma multi-omics for neoantigen discovery. | Mantas P et al. | β | 2026 | β |
| Resource Availability Modulates Gene Expression Across Life Stages in a Migratory Butterfly. | Shipilina D et al. | β | 2026 | β |
| Response of <i>Candida albicans</i> white and opaque cells to phagocytosis by macrophages suggests that opaque cells are "pre-adapted". | Lohse MB et al. | β | 2026 | β |
| Restoring RCAN1 dosage mitigates sleep and EEG abnormalities in a Down syndrome model. | Cain P et al. | β | 2026 | β |
| Rewriting endogenous human transcripts with dual CRISPR-guided 3' trans-splicing. | Chandrasekaran SS et al. | β | 2026 | β |
| RHD6LA regulates root hair responses to both symbionts and commensals. | Tedeschi F et al. | β | 2026 | β |
| RHOT Proteins Link Mitochondrial Motility to Cardiomyocyte Sarcomere Maturation. | Froese N et al. | β | 2026 | β |
| R-loop editing by DNA cytosine deaminase APOBEC3B modulates the activity of oestrogen receptor enhancers. | Zhang C et al. | β | 2026 | β |
| RM2Target v2.0: an updated database for the target genes of writers, erasers, and readers of RNA modifications. | Bao X et al. | β | 2026 | β |
| RNA-binding protein LARP6 coordinates hepatic stellate cell activation and liver fibrosis. | Kim HY et al. | β | 2026 | β |
| RNA cargo profiling of muscle extracellular vesicles identifies candidate biomarkers of disease activity and muscle degeneration in FSHD. | Ragozzino E et al. | β | 2026 | β |
| RNA-coupled CRISPR screens reveal ZNF207 as a regulator of LMNA aberrant splicing in progeria. | Behera AK et al. | β | 2026 | β |
| RNA editing for the treatment of alpha-1 antitrypsin deficiency. | Monian P et al. | β | 2026 | β |
| RNA N6-methyladenosine (m6A) regulates cell cycle progression in diffuse midline glioma (DMG) and confers sensitivity to FTO inhibition. | Ross SE et al. | β | 2026 | β |
| RNA-SeqEZPZ: a point-and-click pipeline for comprehensive transcriptomics analysis with interactive visualizations. | Taslim C et al. | β | 2026 | β |
| RNA-Seq of Cultured Peripheral Blood Lymphocytes Improves Identification of Cryptic Splicing Defects in Rare Disease Diagnostics. | Ren J et al. | β | 2026 | β |
| RNA-Seq reveals flight-induced changes in cerebellar transcriptomic profiles of racing pigeons. | Stefaniuk-Szmukier M et al. | β | 2026 | β |
| RNA Sequencing of Sepsis Patients Informs Tests to Quickly Diagnose Pathogens and Resistance. | Monaghan SF et al. | β | 2026 | β |
| RNA sequencing reveals differential expression of circular RNAs in human small cell lung cancer. | Saxena V et al. | β | 2026 | β |
| Roles of THBS2<sup>+</sup> fibroblasts in malignant transformation of colorectal polyp to cancer. | Han Q et al. | β | 2026 | β |
| RSRC2 is a novel RNA-binding protein that safeguards mitotic fidelity by interacting with the lncRNA C1QTNF1-AS1. | Babaei P et al. | β | 2026 | β |
| RXR Gamma Enables Oligodendrocyte Differentiation by Suppressing Sonic Hedgehog Signaling. | Baldassarro VA et al. | β | 2026 | β |
| S1P-S1PR1 signaling impairs CD8<sup>+</sup> T cell metabolism and effector function in tumors. | Basak D et al. | β | 2026 | β |
| Safety and activity of RO7300490, a bispecific CD40 agonist targeted to fibroblast activation protein, in patients with advanced solid tumors: a single-arm, multicenter, first-in-human, phase 1 trial. | Melero I et al. | β | 2026 | β |
| SASdb: a comprehensive database for sex-biased alternative splicing profiles in human tissues. | Chen X et al. | β | 2026 | β |
| saseR: juggling offsets unlocks RNA-seq tools for fast and scalable differential usage, aberrant splicing and expression retrieval. | Segers A et al. | β | 2026 | β |
| Schlafen 5 is an intracellular immune checkpoint and controls IFN responses in pancreatic ductal adenocarcinoma. | Fischietti M et al. | β | 2026 | β |
| Screening of ester-forming and hydrolyzing enzymes linked to pheromone production in Ips typographus (Linnaeus, 1758). | StrΓ‘dal J et al. | β | 2026 | β |
| SEdb 3.0: a comprehensive super-enhancer database across multiple species. | Song S et al. | β | 2026 | β |
| Selective inhibition of ALDH1A3 impedes breast cancer growth and metastasis by blocking ALDH1A3-driven transcriptional programs. | MacLean MR et al. | β | 2026 | β |
| Selective vulnerability of the aging cholinergic system to amyloid pathology revealed by induced APP overexpression. | Xie K et al. | β | 2026 | β |
| Selenomethionine mitigation of methylmercury-induced epigenetic and transcriptomic alterations in rainbow trout brain: A toxicogenomic survey. | Bidon M et al. | β | 2026 | β |
| Semiautomated Monitoring of Longitudinal Microbial Metabolic Dynamics: A Study Case for Lignin Degradation. | GuimarΓ£es Ferreira JV et al. | β | 2026 | β |
| Senescent-Like Myofibers Contribute to Anti-Regenerative Cytokine Signaling in Duchenne Muscular Dystrophy. | Ikeda M et al. | β | 2026 | β |
| Sensitive CAR T cells redefine targetable CD70 expression in solid tumors. | Hanina SA et al. | β | 2026 | β |
| Separate transcription and splicing gene networks are linked and coordinated by the pRb-E2F pathway. | Carr SM et al. | β | 2026 | β |
| SeqExpressionAnalyser: An R Package for Automated End-to-End RNA-Seq Analysis From Reads to Differential Expression. | Esskhayry S et al. | β | 2026 | β |
| Sequence and chemical specificity define the functional landscape of intrinsically disordered regions. | Langstein-Skora I et al. | β | 2026 | β |
| Sequence-dependent splicing dysregulation drives therapy resistance in pediatric AML. | Huang Y et al. | β | 2026 | β |
| Sequential transcriptional waves and NF-ΞΊB-driven chromatin remodeling direct drug-induced dedifferentiation in cancer. | Su Y et al. | β | 2026 | β |
| Serum from patients with acetylcholine receptor antibody-positive myasthenia gravis triggers pathogenic changes in human myotube cells. | Tanaka K et al. | β | 2026 | β |
| Serum Response Factor (SRF) promotes actin cytoskeletal organization in adipocytes to support adaptive hypertrophic expansion and tissue remodeling during obesity in mice. | So J et al. | β | 2026 | β |
| SETD2 methyltransferase activity promotes correct transcription initiation and termination. | KopczyΕska M et al. | β | 2026 | β |
| SETDB1 enables development beyond cleavage stages by extinguishing the MERVL-driven two-cell totipotency transcriptional program in the mouse embryo. | Zeng TB et al. | β | 2026 | β |
| SETDB1 modulates neuroinflammation in the mouse cortex by regulating neuronal P2rx7 expression. | Zhu Y et al. | β | 2026 | β |
| Sex-biased Expression of Genes and Transposable Elements in Hybrids from Drosophila mojavensis and Drosophila arizonae. | SimΓ£o MC et al. | β | 2026 | β |
| Sex-specific hypothalamic PVN transcriptomic signatures of blood pressure autonomic regulation and neuroinflammation in hypertension. | Duque VJ et al. | β | 2026 | β |
| SFPQ directs histone H3.3 deposition to R-loops in DNA repeats to protect genome stability. | Ferrando A et al. | β | 2026 | β |
| "SHANK3 deficiency alters early progenitor dynamics and reveals shared pathways with neurodegeneration". | Varella-Branco E et al. | β | 2026 | β |
| Shared PRAME epitopes are T-cell targets in NUT carcinoma. | Jensen JL et al. | β | 2026 | β |
| Shear stress-induced Piezo1 activates CD99L2 to facilitate the initiation of blood circulation. | Lu J et al. | β | 2026 | β |
| Short-term caloric restriction partially reprograms immune and microbial networks during acute DSS-induced colitis. | Hechter DTD et al. | β | 2026 | β |
| Signatures of Radiation-Induced Stress and Putative Selection on Immune Targets in Chornobyl Wolves. | Love CN et al. | β | 2026 | β |
| Silencing of the Metabolic Gene HKDC1 Is Associated With Aging and Neurodegeneration in Mice and Humans. | Farooq Z et al. | β | 2026 | β |
| Single amino-acid differences define H2B variants and modify chromatin accessibility to induce EMT in breast cancer. | Dhahri H et al. | β | 2026 | β |
| Single Cell Analysis of Human Heart Failure With Preserved Ejection Fraction. | Hahn VS et al. | β | 2026 | β |
| Single-cell analysis of signalling and transcriptional responses to type I interferons. | Rigby RE et al. | β | 2026 | β |
| Single-cell and spatial transcriptomic profiling of cardiac fibroblasts following myocardial infarction. | HernΓ‘ndez SC et al. | β | 2026 | β |
| Single-cell atlas of hepatitis C virus inoculated tree shrew liver reveals immune activation, metabolic reprogramming, and persistent inflammation. | Yu D et al. | β | 2026 | β |
| Single-cell epigenetic profiling reveals a tumor-intrinsic interferon response program in ccRCC tied to poor prognosis and <i>BAP1</i> loss. | Camp SY et al. | β | 2026 | β |
| Single-cell eQTL mapping reveals cell-type-specific genetic regulation in lung cancer. | Fu Y et al. | β | 2026 | β |
| Single-cell exon deletion profiling reveals splicing events that shape gene expression and cell state dynamics. | Kumari B et al. | β | 2026 | β |
| Single-cell integration and multi-modal profiling reveals phenotypes and spatial organization of neutrophils in colorectal cancer. | Marteau V et al. | β | 2026 | β |
| Single-cell-resolved transcriptional dynamics of human subcutaneous adipose tissue during lifestyle- and bariatric surgery-induced weight loss. | Loft A et al. | β | 2026 | β |
| Single-cell RNA-seq reveals cellular dynamics and emergency hematopoiesis in banana shrimp Penaeus merguiensis hemocytes upon Yellow Head Virus infection. | Koiwai K et al. | β | 2026 | β |
| Single-cell screens identify ADAM12 as a fibroblast checkpoint impeding anti-tumor immunity. | Li J et al. | β | 2026 | β |
| Single-Cell Sequencing Reveals the Immunosuppressive Trajectory in the Tumor Microenvironment of Human Giant Cell Tumor of Bone. | Liu Y et al. | β | 2026 | β |
| Single-cell transcriptome defines cell-type repertoire of adult Daphnia magna. | Krishnan I et al. | β | 2026 | β |
| Single-Cell Transcriptomic Analysis of Macaque LGN Neurons Reveals Novel Subpopulations. | Sun SH et al. | β | 2026 | β |
| Single-Cell transcriptomic analysis reveals distinct cellular and molecular signatures of human oral mucosa and skin. | Shi Y et al. | β | 2026 | β |
| Single-cell transcriptomic resources for tracing neurogenesis and cell fate specification in sea urchin embryos. | Tsuyuzaki K et al. | β | 2026 | β |
| Single-cell transcriptomics reveals targeted modulation of inflammatory repertoire by SOCE blockers. | Stephanou A et al. | β | 2026 | β |
| Single-Cell Triomics Analysis of Tumor Cells Infiltrating Patient-Derived Breast Cancer Scaffolds. | Filges S et al. | β | 2026 | β |
| Single-Nucleus Multi-Omics Reveals Hypoxia-Driven Angiogenic Programs and Their Epigenetic Control in Sinonasal Squamous Cell Carcinoma. | You C et al. | β | 2026 | β |
| Skin tape strips identify age-specific immune, metabolic, and barrier dysregulation signatures in children, adolescents, and adults with allergic asthma. | Liu D et al. | β | 2026 | β |
| SLC7A5 regulates B cell metabolism and plasma cell differentiation independent of leucine transport. | Tao AY et al. | β | 2026 | β |
| Slow RNAPII elongation enhances naive pluripotency rewiring while maintaining high replication fork speed. | MartΓn-VΓrgala S et al. | β | 2026 | β |
| Small molecule splicing modulators that disrupt O-GlcNAc homeostasis. | Cheng SS et al. | β | 2026 | β |
| Small RNA sequencing identifies serum tDR-1:34-Gly-GCC tiRNA levels as a biomarker for survival in amyotrophic lateral sclerosis. | Demaegd KC et al. | β | 2026 | β |
| SMG1:SMG8:SMG9-complex integrity supports efficient execution of nonsense-mediated mRNA decay. | Kueckelmann S et al. | β | 2026 | β |
| Soluble CD83 Accelerates Wound Healing and Attenuates Inflammatory Responses Induced by Chronic Wound Fluid in a Human 3D in Vitro Wound Healing Model. | Hollard C et al. | β | 2026 | β |
| Somatic mosaicism in ALS and FTD identifies focal mutations associated with widespread degeneration. | Zhou Z et al. | β | 2026 | β |
| Somatic mutations distinguish melanocyte subpopulations in human skin. | Tandukar B et al. | β | 2026 | β |
| Soybean RNA polymerases IV and V repress defense response genes and plant immunity. | Wang X et al. | β | 2026 | β |
| Spatial gene expression analysis reveals drivers of extremely early lymph node metastasis in breast cancer. | Nagasawa S et al. | β | 2026 | β |
| Spatially-guided metabolomics profiling of metabolic regions in human tumor tissues. | Lee JJ et al. | β | 2026 | β |
| Spatial Multiomic Analyses Reveal Carcinogenic Pathways in End-Stage Renal Disease. | Takahashi J et al. | β | 2026 | β |
| Spatial multi-omics unveils the monoclonal origin, neuroendocrine plasticity, and microenvironment niches in combined small-cell lung cancer. | Wang Z et al. | β | 2026 | β |
| Spatiotemporal coordination of Slit-Robo repulsion and neurturin-GfrΞ± attraction guides multipolar migration during retinal lamination. | LehtimΓ€ki JI et al. | β | 2026 | β |
| Spatiotemporal molecular profiling of macrophage-fibroblast crosstalk defines checkpoints orchestrating onset and resolution of inflammation. | Weishaupt K et al. | β | 2026 | β |
| Species-specific chromatin architecture and neurogenesis mediated by a human enhancer. | Mosti F et al. | β | 2026 | β |
| Spleen Transcriptome of Nonhuman Primates Exposed to High Doses of Total- or Partial-Body Radiation: Comparisons with Jejunum and Lung. | Vellichirammal NN et al. | β | 2026 | β |
| SpliceHarmonization: an integrated method for identifying RNA splicing events in therapeutics for splicing modulation. | Chen Y et al. | β | 2026 | β |
| Splicing regulation and intron evolution in the short-intron ciliate model of endosymbiosis Paramecium bursaria. | Nguyen TNG et al. | β | 2026 | β |
| SportsXbiodata: A web platform for integrative analysis of exercise-induced gene and protein expression. | Li Z et al. | β | 2026 | β |
| STAT3 mediates an inflammation-induced microbial defense response and regulates pathogen control and clearance by macrophages. | Patel B et al. | β | 2026 | β |
| STAT3 SH2 Domain Aspartic Acid 661 Mutations Activate Immune Gene Programs. | Lee HK et al. | β | 2026 | β |
| Stc1-expressing myofibroblasts are a developmentally distinct lineage cleared through apoptosis in the neonatal lung. | Snitow ME et al. | β | 2026 | β |
| Stem cell control in the lung by an autocrine injury-activated Igf complex. | Zhang Y et al. | β | 2026 | β |
| Stenotrophomonas promotes gastrointestinal tumor progression via STING degradation in tumour cells and mitigated immune response. | Feng H et al. | β | 2026 | β |
| STING activation induces cytotoxic and immune responses in meningiomas via inflammatory cell death pathways. | Youngblood MW et al. | β | 2026 | β |
| Strawberry atlas: <i>Fragaria vesca</i> gene expression atlas for strawberry genomics. | Odagiri M et al. | β | 2026 | β |
| Stress and light spectral quality influence the transcriptome ofΒ a tomato crop on the International Space Station. | Dixit AR et al. | β | 2026 | β |
| Stress controls heterochromatin inheritance via histone H3 ubiquitylation. | Bhatt B et al. | β | 2026 | β |
| Stress-Programmed Immune Niches Fuel TNFR2+ Treg Activation and Drive Neoadjuvant Chemotherapy Resistance in Breast Cancer. | Shao Z et al. | β | 2026 | β |
| Striatal Dysregulation of Angpt2 and Circadian Gene Expression in a Rotenone Rat Model of Parkinson's Disease. | Al Saeedy DY et al. | β | 2026 | β |
| Structural genomics sheds light on protein functions and remote homologs across the insect tree of life. | Wu W et al. | β | 2026 | β |
| Structural insights into cellobiose dehydrogenases of a non-lignocellulolytic fungus and their transcriptional dynamics across different nutritional modes. | Kruhler N et al. | β | 2026 | β |
| Structural variation drives enhancer hijacking via 3D genome disruption in ccRCC. | Dong Y et al. | β | 2026 | β |
| Structure of the MIWI endoribonuclease bound to pachytene piRNAs from mouse testes. | Raad N et al. | β | 2026 | β |
| Stuxnet balances mitochondria homeostasis by regulating uhg5 and parkin. | Zhao X et al. | β | 2026 | β |
| Succinate supplementation ameliorates musculoskeletal defects caused by PLOD3 mutations in a BCARD syndrome model. | Choudhary D et al. | β | 2026 | β |
| SWI/SNF complexes modulate gene expression and the development of physical dependence to ethanol. | Mathies LD et al. | β | 2026 | β |
| Synaptic effects of interleukin-6 on human iPSC-derived dopaminergic neurons. | Huang Y et al. | β | 2026 | β |
| Synergies revealed: RNA-seq study of <i>C. acetobutylicum</i> and <i>C. carboxidivorans</i> co-cultured in the presence of conductive materials. | Feliu-Paradeda L et al. | β | 2026 | β |
| Synergistic intragenic epigenetic deregulation by IDH2 and SRSF2 mutations causes mis-splicing of key transcriptional regulators. | Telonis AG et al. | β | 2026 | β |
| Synergy between regulatory elements can render cohesin dispensable for distal enhancer function. | Hansen KL et al. | β | 2026 | β |
| Systematic evaluation of TCGA tumor microbiota reveals context-dependent reliability. | Ma C et al. | β | 2026 | β |
| Systemic lupus pregnancies are characterized by an intrinsic pro-inflammatory monocyte transcriptome, driven by an aberrant miRNA signature. | Scherlinger M et al. | β | 2026 | β |
| TaAGL6-B1 identified as a candidate gene for the dominant awn-inhibitor locus B2 in wheat. | Mizuno N et al. | β | 2026 | β |
| Talimogene laherparepvec and atezolizumab in HER2-negative breast cancer following neoadjuvant chemotherapy: a window-of-opportunity phase II trial (SOLTI-1503 PROMETEO). | Pascual T et al. | β | 2026 | β |
| Targeted Inhibition of CBP/p300-NCOA3 Interactions with an Ξ±-Methylated Peptide. | Silvestri A et al. | β | 2026 | β |
| Targeting CDK12/13 Drives Mitotic Arrest to Overcome Resistance to KRASG12C Inhibitors. | Stern YE et al. | β | 2026 | β |
| Targeting glycerophospholipid biosynthesis overcomes chemoresistance driven by SLFN11 loss in Ewing sarcoma. | Chakraborty K et al. | β | 2026 | β |
| Targeting NHEJ activates STING signaling through MYC degradation to boost antitumor immunity in SCLC. | Chakraborty S et al. | β | 2026 | β |
| Targeting noncanonical nuclear factor kappa B signalling in CYLD cutaneous syndrome by selective inhibition of IΞΊB kinase alpha. | Hodgson K et al. | β | 2026 | β |
| Targeting PLK1 Reduces MMP10 to Enhance Radiosensitivity in HPV- Head and Neck Cancer. | Korns J et al. | β | 2026 | β |
| Targeting super-enhancer-driven MAB21L2 suppresses neuroblastoma growth and migration. | Chen Y et al. | β | 2026 | β |
| Targeting the lung innate pathways during tuberculosis can improve vaccine-induced protection via Th17 responses in diversity outbred mice. | Ahmed M et al. | β | 2026 | β |
| Targeting Ξ²-catenin degradation with GSK3Ξ² inhibitors induces cell death in acute lymphoblastic leukemia. | Cosgun KN et al. | β | 2026 | β |
| TBL1X/TBL1XR1 govern Ξ²-cell identity through a PAX6-containing gene regulatory network. | Walth-Hummel AA et al. | β | 2026 | β |
| TCPGdb: A Comprehensive T-cell Perturbation Genomics Database for the Identification of Critical T-cell Regulators. | Dong C et al. | β | 2026 | β |
| TDP-43 dysfunction compromises UPF1-dependent mRNA metabolism in ALS. | Alessandrini F et al. | β | 2026 | β |
| TEAD-independent mechanisms of YAP function in cardiomyocyte cell cycle reentry. | Xie B et al. | β | 2026 | β |
| TEffectBayes: a nextflow pipeline for exploring the potential effect of transposable elements in gene regulatory network with multi-omic Bayesian network model. | Kutlu NK et al. | β | 2026 | β |
| Temporal constraints on enhancer usage shape the regulation of limb gene transcription. | Rouco R et al. | β | 2026 | β |
| Temporal dynamics of collateral RNA cleavage by LbuCas13a in human cells. | Bot JF et al. | β | 2026 | β |
| Temporal multiomics gene expression data across human embryonic stem cell-derived polyhormonal cell differentiation. | Keskin A et al. | β | 2026 | β |
| TENT-5 polyadenylates and regulates male-specific transcripts in Caenorhabditis elegans. | Mackiewicz Z et al. | β | 2026 | β |
| TE-SCALE: a comprehensive database for exploring transposable element expression across human cancers at single-cell resolution. | Meng X et al. | β | 2026 | β |
| Tet2 deficiency alters CD4+ T cell function and promotes T cell lymphoma with a TFH cell immunophenotype. | Heavican-Foral TB et al. | β | 2026 | β |
| TET2 loss enhances early response to inflammation in primitive and committed myeloid cells. | Jenkins MT et al. | β | 2026 | β |
| T follicular helper cells transiently unlock a plasticity state in germinal centre B cells during the humoral immune response. | Scourzic L et al. | β | 2026 | β |
| TGF-Ξ²3 promotes trophoblast development in sheep embryos via ACSS2-dependent permissive lipid metabolismβ . | Boffa F et al. | β | 2026 | β |
| TGF-Ξ² mediates epigenetic control of innate antiviral responses and SIV reservoir size. | Ghneim K et al. | β | 2026 | β |
| TGFΞ² signaling promotes cell cycle progression and resistance to the CDK4/6 inhibitor palbociclib through SOX4 transcriptional modulation in breast cancer cells. | Ali MM et al. | β | 2026 | β |
| The 1000 Chinese Pangenome empowers medical and population genetics. | Wang Y et al. | β | 2026 | β |
| The Aging Microenvironment Is a Determinant of Immune Exclusion and Metastatic Fate in Pancreatic Cancer. | Gupta P et al. | β | 2026 | β |
| The Allogeneic FAP-CAR-IL15 iNKT Therapy MiNK-215 Remodels the Tumor Stroma to Enhance Antitumor Immunity. | Chantzoura E et al. | β | 2026 | β |
| The birth, death, and evolutionary compensation of uORFs in Drosophila. | Xu M et al. | β | 2026 | β |
| The bladder cancer m<sup>6</sup>A landscape is defined by global methylation dilution and focal 3'-UTR hypermethylation. | Koch J et al. | β | 2026 | β |
| The C3-C3aR axis drives rotenone-induced cognitive damage via synaptic engulfment, dark microglia and PANoptosis. | Liu J et al. | β | 2026 | β |
| The cell cycle-regulated cytoplasmic kinase, TgCRCK1, is required for efficient propagation of human protozoan pathogen, <i>Toxoplasma gondii</i>. | Ali DH et al. | β | 2026 | β |
| The changing landscape of gene expression analysis. | Zhao Q et al. | β | 2026 | β |
| The Chromosome-Scale Genome Assembly of the Redlip Blenny, Ophioblennius macclurei (Blenniidae). | Kulikov N et al. | β | 2026 | β |
| The clinical significance of the Mediterranean fever gene MEFV variants in Castleman disease. | Du Y et al. | β | 2026 | β |
| The consensus molecular subtypes of esophageal squamous cell carcinoma. | Cui H et al. | β | 2026 | β |
| The CXCL10/CXCR3 axis is essential for sustaining immunological dormancy in triple-negative breast cancer. | Yilmaz A et al. | β | 2026 | β |
| The cyclin dependent kinase (CDK)7 inhibitor BS-181 inhibits pathogenic Cryptococcus species, causing G<sub>2</sub>/M arrest and a splicing defect. | Sethiya P et al. | β | 2026 | β |
| The cytoskeleton contributes to abnormal genome-lamina interactions in LMNA-deficient cardiomyocytes. | Shen KM et al. | β | 2026 | β |
| The dorsal aortic compartment is a developmental source of brown adipose tissue in mice. | Heider S et al. | β | 2026 | β |
| The dynamic landscape and conserved regulation of the m6Am and m6A methylomes during the human and mouse oocyte-to-embryo transition. | Su R et al. | β | 2026 | β |
| The effect of cold ischemia time on hypoxia, EMT, and apoptosis pathways in normal colon mucosa. | Duzowska K et al. | β | 2026 | β |
| The E-Protein Daughterless Regulates Olfactory Learning of Adult <i>Drosophila melanogaster</i>. | Tamberg L et al. | β | 2026 | β |
| The evolution of gene regulation in mammalian cerebellum development. | Sarropoulos I et al. | β | 2026 | β |
| The exon junction complex coordinates the cotranscriptional inclusion of blocks of neighboring exons. | Bergfort A et al. | β | 2026 | β |
| The functional landscape of alternative splicing in hematopoietic lineage commitment. | Hu X et al. | β | 2026 | β |
| The fungal pathogen Rhizoctonia solani AG-8 has 2 nuclear haplotypes that differ in abundance. | Sperschneider J et al. | β | 2026 | β |
| 'The genome assemblies of the Tui chub, Siphateles bicolor, and Arroyo Chub, Gila orcuttii'. | Baker HK et al. | β | 2026 | β |
| The genome of the medicinal plant Uncaria rhynchophylla provides new insights into monoterpenoid indole alkaloid metabolism and its molecular regulatory mechanism. | Mu D et al. | β | 2026 | β |
| The Golden Lancehead Genome Reveals Distinct Selective Processes Acting on Venom Genes of an Island Endemic Snake. | Nachtigall PG et al. | β | 2026 | β |
| The H3K36me3 methyltransferase SETD2 contributes to PAF1C interactions with RNA Pol II and is required for neuronal differentiation. | Ambrosi C et al. | β | 2026 | β |
| The identification of RNA splicing aberrations and their potential regulatory network in Chinese non-small cell lung cancer. | Yan Y et al. | β | 2026 | β |
| The Interferon-miR-146a-5p-Stat1/Nrf2 Pathway Mediates LRRK2-R1441G-induced M1 over M2 Microglia Activation. | Lin L et al. | β | 2026 | β |
| The interplay between the marine diazotroph <i>Vibrio diazotrophicus</i> and its prophage shapes both biofilm structure and nitrogen release. | Mahoudeau L et al. | β | 2026 | β |
| The Interplay of Light Signaling and SlAN1 Expression in Regulating Anthocyanin Accumulation in Fruit Tissues of Purple Tomatoes. | Dos Reis GL et al. | β | 2026 | β |
| The Knowledge Connector decision support system for multiomics-based precision oncology. | HΓΌbschmann D et al. | β | 2026 | β |
| The Landscape of CEACAM5 Expression by Immunohistochemistry in NSCLC. | Hsu YR et al. | β | 2026 | β |
| The long noncoding RNA lnc13 restrains inflammatory responses to maintain oral tolerance to gluten. | Yang-Fischer R et al. | β | 2026 | β |
| The <i>Pseudomonas aeruginosa</i> Cpx system provides a cyclic-di-GMP independent link between cell envelope stress and surface sensing. | O'Malley MR et al. | β | 2026 | β |
| The melon gene CmVTE7 coordinates vitamin E accumulation and heat stress tolerance. | Hu S et al. | β | 2026 | β |
| The Microbiota Shapes Central Nervous System Myelination in Early Life. | Lynch CMK et al. | β | 2026 | β |
| The miRNAome of the honey bee parasite, Varroa destructor, shows sex-specific expression of miRNA clusters across life stages. | McKee RC et al. | β | 2026 | β |
| The nuclear cap-binding complex regulates subcellular RNA processing and surveillance of coding and noncoding RNAs. | Ganguly DR et al. | β | 2026 | β |
| The nuclear cap-binding complex safeguards stress-resistant protein synthesis and proliferation of stem cells. | Oh S et al. | β | 2026 | β |
| The origin of hepatocellular carcinoma depends on metabolic zonation. | Guo J et al. | β | 2026 | β |
| The PagDMG6341-PagWD40-PagPOLD4 Module Coordinates Base Excision Repair in '84K' Poplar (PopulusΒ albaβΓβP. glandulosa). | Ling A et al. | β | 2026 | β |
| The paracrine TAC1-TACR1 signaling promotes endothelial senescence and metastatic progression in neuroblastoma. | Liu X et al. | β | 2026 | β |
| The paradoxical protective effect of chronic stress on advanced Alzheimer's disease pathology. | Shor Y et al. | β | 2026 | β |
| The PIDDosome controls cardiomyocyte polyploidization during postnatal heart development. | Leone M et al. | β | 2026 | β |
| The poplar pathogen <i>Sphaerulina musiva</i> has a dynamic genome architecture marked by chromosomal inversions and changes in transposable element abundance. | Zaccaron AZ et al. | β | 2026 | β |
| The pos-1 3' untranslated region governs germline specification and proliferation to ensure reproductive robustness. | Varderesian HV et al. | β | 2026 | β |
| The proteomic landscape and temporal dynamics of human and mouse gastruloid development. | Garge RK et al. | β | 2026 | β |
| Therapeutic Effects of Noninvasive Electrical Stimulation in Combination Transplantation of Human Adipose-Derived Stem Cells-Derived Dopaminergic Neuron on the Monkey Model of Parkinson's Disease. | Huang C et al. | β | 2026 | β |
| Therapeutic efficacy, biomarker signatures, and translatability of semaglutide in the liver biopsy-confirmed GAN DIO-MASH mouse model. | Kristensen JB et al. | β | 2026 | β |
| Therapeutic efficacy of dendritic cell vaccination in a novel syngeneic mouse model of diffuse hemispheric glioma, H3 G34-mutant. | Owens GC et al. | β | 2026 | β |
| Therapeutic synergies that overcome carboplatin resistance in triple-negative breast cancer. | Altman JE et al. | β | 2026 | β |
| theRNA: a curated knowledgebase of functional RNA therapeutics spanning diverse modalities and disease applications. | Zhou Y et al. | β | 2026 | β |
| The role of low-complexity repeats in RNA-RNA interactions and a deep learning framework for duplex prediction. | Setti A et al. | β | 2026 | β |
| The Role of Sphingolipids in Myocardial Recovery Mediated by Mechanical Unloading and Circulatory Support. | Hamouche R et al. | β | 2026 | β |
| The salicylic acid receptor NPR1 mediates the polyubiquitination and degradation of the transcription factors ABF3/4 to inhibit drought resistance. | Huang C et al. | β | 2026 | β |
| The stem cell atlas of lung adenocarcinoma: A stemness blueprint for prognosis and immunotherapy success. | Yin J et al. | β | 2026 | β |
| The striatal heterogeneous nuclear ribonucleoprotein H1 mRNA targetome associated with methamphetamine administration and behavior. | Ruan QT et al. | β | 2026 | β |
| The transcriptional repressor Fli1 inhibits proteostasis during nutrient stress to limit NK cell persistence in solid tumors. | Ji JH et al. | β | 2026 | β |
| The transcriptional repressor Ssn6 modulates phase separation to regulate fungal gene expression. | Dowell MA et al. | β | 2026 | β |
| The TRIP12's intrinsically disordered region induces chromatin condensates and interferes with nuclear processes. | Vargas C et al. | β | 2026 | β |
| The two-step purification method ViREn identifies a single NSUN6-mediated 5-methylcytosine modification promoting dengue virus RNA genome turnover. | Wu CC et al. | β | 2026 | β |
| The ubiquitin ligase KLHL6 drives resistance to CD8<sup>+</sup> T cell dysfunction. | Cheng H et al. | β | 2026 | β |
| The visual system of the longest-living vertebrate, the Greenland shark. | Fogg LG et al. | β | 2026 | β |
| The WAK/WAKL gene family in Phaseolus vulgaris: genomic characterization and expression under Colletotrichum lindemuthianum infection. | Ferreira GC et al. | β | 2026 | β |
| Three-dimensional genome reorganization foreshadows zygotic genome activation in Drosophila. | Maziak N et al. | β | 2026 | β |
| Time-Dependent Glucocorticoid-Induced Transcriptomic Changes in Human Trabecular Meshwork and Schlemm's Canal Cells. | Mehrotra S et al. | β | 2026 | β |
| Timeβresolved multi-omic analysis of paclitaxel exposure in human iPSCβderived sensory neurons unveils mechanisms of chemotherapyβinduced peripheral neuropathy. | Schinke C et al. | β | 2026 | β |
| Time-resolved transcriptome analysis reveals molecular signatures of Fusarium proliferatum DSM106835-induced sudden decline syndrome in date palm (Phoenix dactylifera L.). | Purayil GP et al. | β | 2026 | β |
| Tissue and Sex-Specific Transcriptomic Signatures Underlying Aggression behavior of Chinese Mitten Crab (Eriocheir sinensis). | Hou J et al. | β | 2026 | β |
| Tissue-specific differences of gene expression variance in mutation accumulation lines of mice. | LΓ³pez-Cortegano E et al. | β | 2026 | β |
| Tolerability and Feasibility of Minimally Invasive Canine Skin Sampling: Excellent Tolerability Meets Transcriptomic Challenges. | Herrmann I et al. | β | 2026 | β |
| Tools and tactics for studying alternative splicing. | Sousa-LuΓs R et al. | β | 2026 | β |
| TORC2 coordinates MBF-dependent transcription and restrains oxidative stress responses during DNA replication stress in fission yeast. | Cohen A et al. | β | 2026 | β |
| Total RNA-seq as a Tool to Study DMD Splicing and Transcriptional Dynamics. | Dunn DM et al. | β | 2026 | β |
| TOX drives CD4<sup>+</sup> T<sub>H</sub>1 effector function, antitumor immunity and autoimmune pathology. | Naizir B et al. | β | 2026 | β |
| Toxic effects of nanoplastics on a model of dog aortic cells. | Basini G et al. | β | 2026 | β |
| Transcriptional Adaptations to Muscle Loading in a Murine Model of Achilles Tendinopathy. | Easley DC et al. | β | 2026 | β |
| Transcriptional plasticity of stromal cells amplifies their differentiation efficiency in vitro. | Jamil AJM et al. | β | 2026 | β |
| Transcriptional Profiling of Cumulus Cells From FLI-Matured Porcine Oocytes Identifies Junctional Genes as Key Components in Oocyte Maturation. | Green CL et al. | β | 2026 | β |
| Transcriptional Response of Durum Wheat During Interaction with <i>Debaryomyces hansenii</i> and <i>Fusarium graminearum</i>. | Pluskota WE et al. | β | 2026 | β |
| Transcriptional responses to proteotoxic stressors are profoundly diverse and tissue-specific. | Rabenius A et al. | β | 2026 | β |
| Transcriptional stratification of necrotizing enterocolitis identifies distinct disease subtypes. | Lee J et al. | β | 2026 | β |
| Transcription and potential functions of a novel <i>XIST</i> isoform in male peripheral glia. | O'Leary KS et al. | β | 2026 | β |
| Transcription elongation can be sufficient, but is not necessary, to advance replication timing. | Vouzas AE et al. | β | 2026 | β |
| Transcription factor NFYA directs male meiotic entry by regulating accessible chromatin at meiotic promoters in mice. | SΓ€flund M et al. | β | 2026 | β |
| Transcription termination counteracts DNA damage after WEE1 inhibition. | Landsverk HB et al. | β | 2026 | β |
| Transcriptome Analysis of Adipose Tissues from Five Sheep Breeds Reveals Key Genes Involved in Fat Deposition. | Yu Y et al. | β | 2026 | β |
| Transcriptome analysis of patients with loss-of-function POGZ variants in four unrelated Chinese families. | Wu Y et al. | β | 2026 | β |
| Transcriptome analysis reveals KRAS as a crucial regulator of ovarian follicle development in Wuding chickens. | Zhu W et al. | β | 2026 | β |
| Transcriptome- and Epigenome-Wide Association Studies of Tic Spectrum Disorder in Discordant Monozygotic Twins. | Dalsberg J et al. | β | 2026 | β |
| Transcriptome-based high-frequency recurrence index predicts frequent recurrence in non-muscle-invasive bladder cancer after Bacillus Calmette-GuΓ©rin therapy. | Baek SW et al. | β | 2026 | β |
| Transcriptome changes in circulating immune cells of critical COVID-19 patients predict a specific metabolic and epigenetic imprint. | Virga F et al. | β | 2026 | β |
| Transcriptome profiling indicates varied gene responses to Pasteurella multocida mutant infections in cattle. | Ma H et al. | β | 2026 | β |
| Transcriptome-Proteome Analysis of Human Naive and Memory B Cell Subsets Reveals Isotype and Subclass-Specific Phenotypes. | Koers J et al. | β | 2026 | β |
| Transcriptome sequencing and weighted correlation network analysis reveal the molecular mechanism of growth variation in highly resistant transgenic double Bt poplar. | He Z et al. | β | 2026 | β |
| Transcriptome-wide analysis of genes associated with collagen III in human skin. | Chen M et al. | β | 2026 | β |
| Transcriptome wide evidence of interspecies differences in the regulation of photoprotection between chilling-tolerant and -sensitive mangrove species. | Short AW et al. | β | 2026 | β |
| Transcriptomic analyses reveal regulatory plasticity and metabolic reprogramming underlying genotype-specific microspore embryogenesis in wheat. | Yuan HY et al. | β | 2026 | β |
| Transcriptomic analysis of BPA alternative chemicals in primary human mammary epithelial cells. | Matteo G et al. | β | 2026 | β |
| Transcriptomic Analysis of Early Fruit Development in Micro-Tom Tomato Reveals Conserved and Cultivar-Specific Mechanisms. | Ferreira PB et al. | β | 2026 | β |
| Transcriptomic analysis of non-model Drosophilidae reveals novel AMP candidates. | Dhakad P et al. | β | 2026 | β |
| Transcriptomic analysis of preimplantation mouse embryos exposed to nanoplastics using RNA sequencing. | You HJ et al. | β | 2026 | β |
| Transcriptomic Analysis of the Amygdala in Subjects with Schizophrenia, Bipolar Disorder and Major Depressive Disorder Reveals Differentially Altered Metabolic Pathways. | Zhang X et al. | β | 2026 | β |
| Transcriptomic analysis reveals a crucial role of the yolk sac during Avian Pathogenic Escherichia coli infection in chicken embryos. | Wang J et al. | β | 2026 | β |
| Transcriptomic analysis reveals functional compartmentalization of the digestive tract in Urechis unicinctus. | Ryu KB et al. | β | 2026 | β |
| Transcriptomic and metabolomic changes associated with the induction and initiation of juice sacs in citrus fruit. | Assili S et al. | β | 2026 | β |
| Transcriptomic and phenotypic convergence of neurodevelopmental disorder risk genes in vitro and in vivo. | Fernandez Garcia M et al. | β | 2026 | β |
| Transcriptomic Insights into Endophytic Fungus-Mediated Enhancement of Root Growth and Stress Resistance in <i>Phoebe bournei</i>. | Chen Z et al. | β | 2026 | β |
| Transcriptomic Insights Into the Effect of LuxP-Targeting DNA Aptamer Developed by Ni-NTA SELEX in Pathogenic Vibrio spp. | Yusof NAM et al. | β | 2026 | β |
| Transcriptomic insights into unisexual flower development in Cannabis sativa: conserved MADS-box networks and divergent developmental programs. | Lavie O et al. | β | 2026 | β |
| Transcriptomic landscape of transposable elements reveals <i>LTR7</i>-<i>PLAAT4</i> as a potential oncogene and therapeutic target in pancreatic adenocarcinoma. | Shi M et al. | β | 2026 | β |
| Transcriptomic landscapes of the endometrium of dairy cows with clinical or subclinical endometritis. | Xie L et al. | β | 2026 | β |
| Transcriptomic plasticity in hybrid schistosomes can contribute to their zoonotic potential. | Luviano Aparicio N et al. | β | 2026 | β |
| Transcriptomic profiling of co-cultured cancer-host cells identifies hypoxia as a driver of the skeletal muscle cell's anti-proliferative effect on cancer cells. | Aunan A et al. | β | 2026 | β |
| Transient hypoxia followed by progressive reoxygenation is required for muscle repair. | QuΓ©tin M et al. | β | 2026 | β |
| Transition From Land to Sea: Comparative Genomics Illuminates the Adaptive Evolution of the Intertidal Spider. | Li F et al. | β | 2026 | β |
| Transposable element-gene chimera cartography, origination and role in enhancing transcriptome plasticity. | Cheon Y et al. | β | 2026 | β |
| Transposable elements as drivers of genome evolution in Drosophila virilis. | Rezvykh AP et al. | β | 2026 | β |
| Transposable elements contribute to the evolution of host shift-related genes in cactophilic <i>Drosophila</i> species. | Siqueira de Oliveira D et al. | β | 2026 | β |
| Trans-Splicing Enhances Processivity of RNA Polymerase II and Suppresses Polyadenylation Signals. | Soldatova IV et al. | β | 2026 | β |
| Treatment resistance to platinum-based chemotherapy in lung and ovarian cancer is driven by a targetable TGFΞ² senescent secretome. | GonzΓ‘lez-Gualda E et al. | β | 2026 | β |
| TRH can stimulate the release of two POMC-derived pituitary hormones, ACTH and MSH, in medaka. | Yamakawa M et al. | β | 2026 | β |
| Trisomy 21 Drives ADARB1 Overexpression and Premature RNA Recoding in the Developing Fetal Brain. | Breen MS et al. | β | 2026 | β |
| TRPM3 mediates spontaneous pain and mechanical allodynia in a mouse model of chronic orofacial neuropathy. | Deseure K et al. | β | 2026 | β |
| TSniffer: unbiased de novo identification of RNA editing sites and quantification of editing activity in RNA-seq data. | Herrmann M et al. | β | 2026 | β |
| Tumor DNA methylation subtypes predict immunotherapy outcomes in pleural mesothelioma patients in the NIBIT-EPI-MESO study. | CalabrΓ² L et al. | β | 2026 | β |
| Tumor ecosystem and microbiome features associated with efficacy and resistance to avelumab plus chemoradiotherapy in head and neck cancer. | Riaz N et al. | β | 2026 | β |
| Tumor-localized CD40 agonism with MP0317, a FAP x CD40 DARPin, reprograms the tumor microenvironment in patients with advanced solid tumors: an open-label, nonrandomized, dose-escalation phase 1 study. | Steeghs N et al. | β | 2026 | β |
| Tumor-reactive TCRs within exhausted TILs reveal cancer type-specific immune landscapes in renal cell carcinoma. | Komahashi M et al. | β | 2026 | β |
| Tumor-suppressive role of miR-216b impacts cell cycle regulation in high-grade glioma. | Lang A et al. | β | 2026 | β |
| Two independent origins of XY sex chromosomes in Asparagus. | Bentz PC et al. | β | 2026 | β |
| Two LEAFY homologues regulate floral patterning and development without affecting flowering time in kiwifruit. | Peng Y et al. | β | 2026 | β |
| Type I interferon-dependent and -independent signaling underlie autoantibody production in a murine lupus model. | Levine JS et al. | β | 2026 | β |
| umite: fast quantification of Smart-seq3 libraries with improved UMI retrieval. | Foerster LC et al. | β | 2026 | β |
| UnanchoredΒ K63-linkedΒ polyubiquitinΒ chains: a novel second messenger involved inΒ G protein-coupled receptors early signaling events. | Doyon P et al. | β | 2026 | β |
| Uncovering the genome evolutionary dynamics of the Mediterranean endemic palm Chamaerops humilis. | Labella-Ortega M et al. | β | 2026 | β |
| Unique territorial and compartmental organization of chromosomes in the holocentric silkworm. | Gil J et al. | β | 2026 | β |
| Unmasking FCGR2B as a high-grade serous ovarian cancer specific marker of immune suppression and tumor progression through multi-omics mining. | Zhou J et al. | β | 2026 | β |
| Unraveling CD8 lineage decisions reveals that functionally distinct CD8<sup>+</sup> T cells are selected by different MHC-I thymic peptides. | Shinzawa M et al. | β | 2026 | β |
| Unraveling molecular thermotolerance mechanisms in the wild rice species Oryza australiensis. | Lima-Melo Y et al. | β | 2026 | β |
| Unraveling small non-coding RNAs with a significant post-transcriptional impact on breast cancer cell signaling, using a combinational sequencing approach. | Katsaraki K et al. | β | 2026 | β |
| Unraveling the arsenite response mechanisms in the facultative anaerobe Aromatoleum sp. CIB. | Alonso-Fernandes E et al. | β | 2026 | β |
| Unravelling the molecular mechanisms of vegetative-to-reproductive transition in Cynara cardunculus by RNA-Seq analysis. | Paulino A et al. | β | 2026 | β |
| Unravelling the progression of the zebrafish primary body axis with reconstructed spatiotemporal transcriptomics. | Dong Y et al. | β | 2026 | β |
| Unveiling Functional Long-Range RNA Structures via RIC-seq Analysis. | Margasyuk S et al. | β | 2026 | β |
| Unveiling ribosomal dysfunction and impaired signaling pathways in the cortical region of 5xFAD mice. | Agrawal K et al. | β | 2026 | β |
| Uptake of polystyrene nanoplastics by cumulus-oocyte complexes impairs oocyte and embryo development. | Yang J et al. | β | 2026 | β |
| Using transcriptomic data to improve the prediction of immunity traits in pigs. | JovΓ©-JuncΓ T et al. | β | 2026 | β |
| Utilisation of Machine Learning Approaches Improves RNA-Seq Transcriptome Analyses in Alzheimer's Disease Brain. | Cheng Y et al. | β | 2026 | β |
| VAMP7-dependent late endosomal secretion of ER and mitochondrial proteins impacts the tumor microenvironment and macrophage engagement. | Vats S et al. | β | 2026 | β |
| Variable A-type lamin expression in Merkel cell carcinoma cell lines and its association with nuclear integrity. | Stiekema M et al. | β | 2026 | β |
| Variant U1 snRNAs contribute to cell cycle and differentiation control of human iPS cells. | Zhu Y et al. | β | 2026 | β |
| Variation in guide RNA library representation results in gene effect score bias in genome-wide CRISPR screens. | Metz P et al. | β | 2026 | β |
| Vernalization attenuates age-dependent decline of glucosinolates in cabbage (Brassica oleracea ssp. capitata) through coordinated transcriptomic and metabolomic reprogramming. | Moon H et al. | β | 2026 | β |
| Vertebrate-wide transcriptomic screening identifies immune cell-specific expression of the conserved OR-ΞΊ gene. | Nishiura K et al. | β | 2026 | β |
| Vertical RAS pathway inhibition in pancreatic cancer drives therapeutically exploitable mitochondrial alterations. | Hafner P et al. | β | 2026 | β |
| Violence-Related Distress, Nasal Epithelial Gene Expression, and T17-High Asthma in Youth. | Yue M et al. | β | 2026 | β |
| VΞ³1 Ξ³Ξ΄ T cells steer airway macrophages toward a profibrotic response in an autochthonous lung cancer mouse model. | Raffo-Iraolagoitia XL et al. | β | 2026 | β |
| When RNA goes off script: ensuring transcript fidelity in transgene expression. | Anderson R et al. | β | 2026 | β |
| Whole blood gene expression to assess disease severity of omicron-associated acute encephalitis and croup in children: A transcriptomic and immune profiling study. | Huang CW et al. | β | 2026 | β |
| Whole blood transcriptional signatures of age and survival identified in long life family and integrative longevity omics studies. | Li M et al. | β | 2026 | β |
| Whole-Body Knockout of the AhR (Aryl Hydrocarbon Receptor) Ameliorates Atherosclerosis Due to Altered Lipid Metabolism-Brief Report. | Huchzermeier R et al. | β | 2026 | β |
| Whole genome analysis of toxic Papilionidae butterflies utilizing aristolochic acid, Pachliopta aristolochiae, and Byasa alcinous. | Komata S et al. | β | 2026 | β |
| Whole-transcriptome identification of deleterious variants in candidate genes linked to bovine paratuberculosis. | Badia-BringuΓ© G et al. | β | 2026 | β |
| Widespread intron retention and exon skipping characterise alternative splicing changes in a C. elegans model of spinal muscular atrophy. | Rashid S et al. | β | 2026 | β |
| YAP1 Enhances Mesenchymal-Type Gene Expression in Human Adrenergic-Type Neuroblastoma Cells. | Ludwig M et al. | β | 2026 | β |
| YAP Induces a Prorenewal Metabolic State in Cardiomyocytes. | Liu L et al. | β | 2026 | β |
| YAP/TAZ-VGLL3 governs adipocyte fate via epigenetic reprogramming of PPARΞ³ and its target enhancers. | Seol T et al. | β | 2026 | β |
| ZAP targets aberrant mRNA transcripts encoding proteins with defective signal peptides for degradation. | Shah A et al. | β | 2026 | β |
| ZFP57 is a regulator of postnatal growth and life-long health. | Hanin G et al. | β | 2026 | β |
| ZIKV envelope protein is a strong blocker of early directional differentiation in the neural lineage. | Ma ZH et al. | β | 2026 | β |
| Zooming into rearranged genome: applying pipeline of cytological, genomic, and transcriptomic methods for structural variant interpretation. | Gridina M et al. | β | 2026 | β |
| Ξ²1,4-galactosyltransferase III drives retinoblastoma invasion via activation of integrin-FAK axis. | Tang J et al. | β | 2026 | β |
| Ξ³Ξ΄ T cell-derived IL-4 initiates CD8<sup>+</sup> T cell immunity. | Le S et al. | β | 2026 | β |
| ΞNp73 isoform defines a TP53-mutant-like poor-risk subgroup of acute myeloid leukemia. | Pereira-Martins DA et al. | β | 2026 | β |
| 1,24,25(OH)<sub>3</sub>D<sub>3</sub> is a fully active catabolite of vitamin D in keratinocytes. | DomΕΌalski P et al. | β | 2025 | β |
| AAV-delivered engineered suppressor tRNA rescues visual function in mice with an inherited retinal disease. | Ren C et al. | β | 2025 | β |
| A chromosome-level genome assembly for the brown sea cucumber from the GalΓ‘pagos Islands, Isostichopus fuscus. | Ortiz-Pachar JD et al. | β | 2025 | β |
| Activation of FCGR2A enhances the antitumor efficacy of hPSC-derived CAR-M. | Yang X et al. | β | 2025 | β |
| A defined bacterial consortium and spatial transcriptomics highlight the complex interaction between <i>Campylobacter jejuni</i> and the murine intestine. | Chitre S et al. | β | 2025 | β |
| A diet-induced obese and diabetic host phenotype reduces mosquito ZIKV infections and remodels gut metabolism. | Menezes A et al. | β | 2025 | β |
| A human iPSC-based neural spheroid platform for modelling glioblastoma infiltration using high-content imaging. | Tsang VSK et al. | β | 2025 | β |
| Airway transcriptome networks for ozone and PM<sub>2.5</sub> exposure reveal distinct key drivers for children with asthma. | Chun Y et al. | β | 2025 | β |
| Alternative splicing patterns in genetic subtypes of diffuse large B-cell lymphoma. | An S et al. | β | 2025 | β |
| A lung specific escape of intravascular metastatic breast cancer cells from cytotoxic T cell killing. | Kizner M et al. | β | 2025 | β |
| A metabolism-chromatin axis promotes differential ribosomal RNA transcription in the human malaria parasite. | Couble JE et al. | β | 2025 | β |
| A multi-omics analysis of human fibroblasts overexpressing an Alu transposon reveals widespread disruptions in aging-associated pathways. | Bravo JI et al. | β | 2025 | β |
| Analysis of a near telomere-to-telomere genome of Phellodendron amurense reveals insights into berberine biosynthesis. | Chen S et al. | β | 2025 | β |
| Analyzing the effects of benzodiazepines on the virulence and biofilm formation of Pseudomonas aeruginosa. | BarcelΓ³ IM et al. | β | 2025 | β |
| An epigenetic repressor TRIM66 dictates monogenic olfactory receptor expression, neural activity, and olfactory behavior. | Bao H et al. | β | 2025 | β |
| A novel accessible in vitro model of proliferative vitreoretinal diseases shows facilitated epithelial mesenchymal transition through aquaporin-1. | Datlibagi A et al. | β | 2025 | β |
| Anti-cancer activity of propolis extracts from stingless bees of Brunei Darussalam. | Lim BY et al. | β | 2025 | β |
| Antisense transcription can induce expression memory via stable promoter repression. | Mutzel V et al. | β | 2025 | β |
| A platelet transcriptomic signature of thromboinflammation predicts cardiovascular risk. | Beitzen-Heineke A et al. | β | 2025 | β |
| A practical framework for predicting splicing single nucleotide variants in exome sequencing. | Utsuno Y et al. | β | 2025 | β |
| A single-cell atlas of RNA alternative splicing in the glioma-immune ecosystem. | Song X et al. | β | 2025 | β |
| ASPEN: Robust detection of allelic dynamics in single cell RNA-seq. | Petrova V et al. | β | 2025 | β |
| A systematic scoring system to optimise the testing of neurotherapeutics in models of perinatal brain injury, with an applied case study of human umbilical-cord MSC. | Bokobza C et al. | β | 2025 | β |
| Benchmarking Software for DDA-PASEF Immunopeptidomics. | Chen Y et al. | β | 2025 | β |
| Capsular polysaccharide of Mycoplasma mycoides subsp. capri contributes to phenotypic diversity promoting distinctive immune responses. | Yimthin T et al. | β | 2025 | β |
| Carbonic Anhydrase 3 Overexpression Modulates Signalling Pathways Associated with Cellular Stress Resilience and Proteostasis. | Yu Y et al. | β | 2025 | β |
| Cardiometabolic and molecular adaptations to 6-month intermittent fasting in middle-aged men and women with overweight: secondary outcomes of a randomized controlled trial. | Barve RA et al. | β | 2025 | β |
| CDK4/6 inhibition reprograms the breast cancer immunopeptidome via Rb-dependent chromatin and transcriptomic remodeling. | Minati R et al. | β | 2025 | β |
| Cellular reprogramming of H3K27M pediatric high-grade glioma to neuron-like state. | Uthamacumaran A et al. | β | 2025 | β |
| Chromosome level genome assembly of tea tussock moth, Euproctis pseudoconspersa. | Zhang K et al. | β | 2025 | β |
| Chromosome-level genome of Proserpinaca palustris reveals key KNOX genes related to heterophylly formation. | Dong Y et al. | β | 2025 | β |
| Collision-induced ribosome degradation driven by ribosome competition and translational perturbations. | Li S et al. | β | 2025 | β |
| Combined Vacuum and Ascorbic Acid Treatment Enhances Texture and Antioxidant Capacity in Fresh-Cut Potatoes: Transcriptomic Elucidation of Glutathione Metabolism Mechanisms. | Fang R et al. | β | 2025 | β |
| Comparative TSS-seq analysis among natural variations of <i>Arabidopsis</i> reveals the genetic stability of genic and nongenic promoters. | Sugekawa K et al. | β | 2025 | β |
| Comprehensive pathogen diagnostics in wild fish populations using blood-based molecular strategies: an Atlantic herring case study. | Caza F et al. | β | 2025 | β |
| Concurrent PIK3CA mutant promotes cachexia through inflammatory signaling in EGFR mutant lung cancer. | Yue M et al. | β | 2025 | β |
| Conserved HSFA1-dependent chromatin dynamics drive heat stress responses in plants. | Yen MJ et al. | β | 2025 | β |
| Consuming your colors: carotenoid and retinol availability affects expression of color related genes in the mimic poison frog (Ranitomeya imitator). | Rubio AO et al. | β | 2025 | β |
| Control of 3' splice site selection in <i>S. cerevisiae</i> by a highly conserved amino acid within the Prp8 Ξ±-finger domain. | Liu Y et al. | β | 2025 | β |
| Cooperation between architectural C2H2 proteins in CP190 recruitment to Drosophila regulatory elements. | Maksimenko O et al. | β | 2025 | β |
| c-Rel drives pancreatic cancer metastasis through fibronectin-integrin signaling-induced isolation stress resistance and EMT. | BakΔ±rdΓΆΔen D et al. | β | 2025 | β |
| Crosstalk between H3K4me3 and oxidative stress is a potential target for the improvement of ART-derived embryos. | Zhang C et al. | β | 2025 | β |
| Crosstalk between the ribosome quality control-associated E3 ubiquitin ligases LTN1 and RNF10. | Huang Y et al. | β | 2025 | β |
| DEC1 regulates human Ξ² cell functional maturation and circadian rhythm. | Preza S et al. | β | 2025 | β |
| Decoding molecular signatures and identifying therapeutic targets in triple-negative breast cancer subtypes using omics and network analysis. | Sanyal D et al. | β | 2025 | β |
| Deletion of Ptpn2 in B cells promotes autoimmunity via TLR and JAK/STAT signaling. | Alexander BN et al. | β | 2025 | β |
| Design of precision therapeutics for a CKD risk allele by targeting Shroom3-Rock interaction. | Reghuvaran A et al. | β | 2025 | β |
| Detection of Expressed <i>Otx</i> mRNA Isoforms in Sea Urchins by Mapping NGS Reads to Single-Gene/Transcript Sequences. | Maiorova MA et al. | β | 2025 | β |
| Determinants of sensitivity to HER2-targeted antibody drug conjugates in urothelial cancer. | Chen Z et al. | β | 2025 | β |
| Developmental dynamic transcriptomics reveals multiple effectors and transcription factors critical for Ditylenchus destructor parasitism. | Chen Y et al. | β | 2025 | β |
| Diet-Driven Microglial Activation: Region-Specific Neuroinflammation in the Mouse Brain. | Plantera L et al. | β | 2025 | β |
| Differential effects on tumor progression by APOBEC3A, APOBEC3B, and APOBEC3H Haplotype I in a breast cancer mouse xenograft model. | Granadillo RodrΓguez M et al. | β | 2025 | β |
| Dissecting the functional roles of CTCF and CTCF-s in human embryonic stem cells. | Zhong H et al. | β | 2025 | β |
| Divergent immune responses to commensal bacteria bearing distinct motility signatures. | Duck LW et al. | β | 2025 | β |
| D-lactic acid inhibits Candida albicans associated with vulvovaginal candidiasis: in vitro and in vivo effects and underlying mechanisms. | Xia T et al. | β | 2025 | β |
| DOCK10 Regulates Insulin Hypersecretion in Insulinoma and Serves as a Diagnostic and Therapeutic Target. | Katsuda H et al. | β | 2025 | β |
| Double stranded RNA sensing is silenced during early embryonic development. | Witteveldt J et al. | β | 2025 | β |
| Effect of creep-feeding supplementation during the pre-weaning phase on gene co-expression in Longissimus thoracis muscle of F1 Angus x Nellore calves at weaning. | Reolon HG et al. | β | 2025 | β |
| Effects of Environmental Salinity on the Regulation of Trace Metals and Associated Transporters in the Euryhaline Tilapia (Oreochromis mossambicus). | Cao K et al. | β | 2025 | β |
| Egr1 is a sex-dependent regulator of neuronal chromatin, structural plasticity, and behaviour. | Rocks D et al. | β | 2025 | β |
| Enhancing Cryopreservation Efficiency in <i>Populus davidiana</i> Γ <i>P. tremuloides</i> Shoot Tips: Optimization of Vitrification Protocols and Mechanistic Insights into Flavonoid-Mediated Stress Adaptation. | Yang P et al. | β | 2025 | β |
| Epidermal cell fusion promotes the transition from an embryonic to a larval transcriptome in C. elegans. | Funk OH et al. | β | 2025 | β |
| Epigenetic and transcriptomic alterations precede amyloidosis in the Alzheimer's disease App<sup>NL-G-F</sup> knock-in mouse model. | Okhovat M et al. | β | 2025 | β |
| Epithelial WNT secretion drives niche escape of developing gastric cancer. | Lee J et al. | β | 2025 | β |
| Epstein-Barr Virus Promotes Gastric Cancer Progression by Modulating m6A-Dependent YTHDF1-TSC22D1 Axis. | An YR et al. | β | 2025 | β |
| Establishment and maintenance of NRT2.1 inter-individual variability in plants. | Lecuyer C et al. | β | 2025 | β |
| Excess prenatal folic acid supplementation alters cortical DNA methylation and gene expression networks. | Haghani V et al. | β | 2025 | β |
| Expression of antibody-drug conjugate targets in post-mortem samples of breast cancer metastases and normal tissue. | Borremans K et al. | β | 2025 | β |
| Functional Expansion of the Skin Microbiome: A Pantothenate-Producing <i>Rothia</i> Strain Confers Anti-Inflammatory and Photoaging-Protective Effects. | Kim HB et al. | β | 2025 | β |
| Functionally diversified Caenorhabditis elegans BiP orthologs control body growth, reproduction, stress resistance, aging, and autophagy. | Urban ND et al. | β | 2025 | β |
| Fusions4U: a resource of validated and annotated gene fusions in 328 cancer cell lines. | Alamshahi A et al. | β | 2025 | β |
| Gap-Free T2T assemblies of Micropterus salmoides identify a Y-Linked SV hotspot underlying sexual dimorphism. | Liu S et al. | β | 2025 | β |
| Gene expression differences in Bemisia tabaci following acquisition of an Old World begomovirus. | Lahey Z et al. | β | 2025 | β |
| Genomic alterations linked to recurrence risk in high-grade serous ovarian cancer revealed by deep targeted sequencing. | Park YH et al. | β | 2025 | β |
| Global remodeling of ADP-ribosylation by PARP1 suppresses influenza A virus infection. | Zhang Z et al. | β | 2025 | β |
| GPR88 promotes neurite outgrowth of sensory neurons via activation of G<sub>i/o</sub>. | Γn D et al. | β | 2025 | β |
| H2AK119ub dynamics control hair follicle stem cell quiescence. | Flora P et al. | β | 2025 | β |
| H3K36 Methylation as a Guardian of Epigenome Integrity. | Padilla R et al. | β | 2025 | β |
| Heat-induced transcriptional activation of LTR retrotransposons in the regenerative flatworm Macrostomum lignano. | Ustyantsev K et al. | β | 2025 | β |
| Heterogeneity of the intestinal mononuclear phagocyte compartment in health and inflammatory bowel disease. | Fenton TM et al. | β | 2025 | β |
| High-Fidelity and Cost-Effective Engineering of SARS-CoV-2. | Olguin-Nava M et al. | β | 2025 | β |
| HIV-induced sialoglycans on infected CD4+ T cells promote immune evasion from myeloid cell-mediated killing. | Singh S et al. | β | 2025 | β |
| Host-resistance in <i>Allium</i> genotypes against pantaphos producing <i>Pantoea ananatis</i>. | Myers BK et al. | β | 2025 | β |
| Identification of DNA methylation based prognostic subtype and signature in epithelial ovarian cancer. | Zhou J et al. | β | 2025 | β |
| Identification of food deprivation in salmonids using gill biomarkers. | Bugg WS et al. | β | 2025 | β |
| IL-17A is increased in diabetic wounds and impairs keratinocyte function via histone demethylase JMJD3. | Moon JY et al. | β | 2025 | β |
| Improved reannotations of Aegilops umbellulata (PI 554389) genome and transcriptomics data provide candidates for leaf rust resistance for wheat improvement. | Singh J et al. | β | 2025 | β |
| Industrialization of 3D hiPSC-cardiac microtissues for high-throughput cardiac safety and drug discovery screening. | de Korte T et al. | β | 2025 | β |
| Inheritance of DNA Methylation Patterns and Its Role in Modulating Allelic Expression in <i>Camellia</i> F<sub>1</sub> Hybrids. | Zhang M et al. | β | 2025 | β |
| Integrated single-cell and bulk transcriptomic analysis reveals shared pathogenesis and prognostic biomarkers in breast and thyroid cancers. | Shen B et al. | β | 2025 | β |
| Integrated stress response inhibition prolongs the lifespan of a Pelizaeus-Merzbacher disease mouse model by increasing oligodendrocyte survival. | Chen Y et al. | β | 2025 | β |
| Integrating Multi-omics Analysis to Decipher the Genetic Basis of Heterosis in Xieyou9308. | Lin F et al. | β | 2025 | β |
| Integration of single-cell and bulk transcriptomics uncovers CHST6 as a shared pathogenic driver in idiopathic pulmonary fibrosis and lung cancer. | Mao S et al. | β | 2025 | β |
| Integrative analysis of morphological, transcriptomic, and metabolomic approaches to uncover the function of flavonoids in the salt stress response of <i>Alhagi camelorum</i>. | Tang G et al. | β | 2025 | β |
| Integrative Transcriptomic and Perturbagen Analyses Reveal Sex-Specific Molecular Signatures Across Glioma Subtypes. | Rami Reddy MVSR et al. | β | 2025 | β |
| INTS1 is required for maintaining accurate transcriptional integrity and behavior in zebrafish. | Confino S et al. | β | 2025 | β |
| Investigating the transcriptional fingerprints of cocultured <i>Saccharomyces cerevisiae</i> and <i>Lachancea thermotolerans</i> in a model wine environment. | Asmus JJ et al. | β | 2025 | β |
| Lack of caspase 8 directs neuronal progenitor-like reprogramming and small cell lung cancer progression. | Androulidaki A et al. | β | 2025 | β |
| Left ventricular transcriptome and extracellular vesicle-derived miRNAs in porcine donation after circulatory death (DCD) hearts undergoing prolonged working mode ex situ perfusion. | Wang F et al. | β | 2025 | β |
| Leukemia-expanded splenic CD81+ erythroblasts potentiate disease progression in mice by reshaping leukemic cell metabolism. | Li Y et al. | β | 2025 | β |
| Lifestyles shape genome size and gene content in fungal pathogens. | Fijarczyk A et al. | β | 2025 | β |
| LINE-1 retrotransposition in a mouse TDP-43 model of neurodegeneration marks motor cortex neurons for cell-intrinsic and cell non-autonomous programmed cell death. | Korada S et al. | β | 2025 | β |
| Lipid scavenging by the Lyme disease spirochete Borrelia burgdorferi. | Gwynne PJ et al. | β | 2025 | β |
| LncRNA CISTR-ACT regulates cell size in human and mouse by guiding FOSL2. | Kiriakopulos K et al. | β | 2025 | β |
| Longitudinal gene expression analysis in COVID-19 sepsis highlights dynamic immune, cellular, and metabolic dysfunction in high severity patients. | An AY et al. | β | 2025 | β |
| Long-term evaluation of human iPSC-derived cartilage for repairing chondral defects. | Lu Y et al. | β | 2025 | β |
| Low dose IFNΞ³ remodels enhancer landscape to potentiate mesenchymal stromal cell activation. | Lin J et al. | β | 2025 | β |
| Mechanisms of resistance to trastuzumab deruxtecan in breast cancer elucidated by multi-omic molecular profiling. | Sledge GW et al. | β | 2025 | β |
| Metabolic profiling of therapy-induced senescent cancer cells via TPEF, MALDI-MS, and RNA-sequencing. | Ghislanzoni S et al. | β | 2025 | β |
| Microbiome analysis of 940 lung cancers in never-smokers reveals lack of clinically relevant associations. | McElderry JP et al. | β | 2025 | β |
| Miniature inverted repeat transposable elements in the genome of sugar beet and their impact on gene expression. | MoraΕska E et al. | β | 2025 | β |
| Modulation of the Apolipoprotein M/S1PR4 Pathway Reduces Podocyte Lipid Overload in Alport Syndrome via Distinct Autophagy and Efflux Mechanisms. | Tolerico M et al. | β | 2025 | β |
| Molecular and immune determinants of response in locally advanced deficient DNA mismatch repair/microsatellite instability-high gastric or gastroesophageal junction adenocarcinoma treated with neoadjuvant chemoimmunotherapy. | Yu P et al. | β | 2025 | β |
| Molecular architecture of mesoderm cells across early to middle stage of human embryo development at single-cell resolution. | Zhang W et al. | β | 2025 | β |
| Molecular Effects of Glucose on <i>MIR503HG</i>-Regulated Genes in Triple-Negative Breast Cancer. | Reid VA et al. | β | 2025 | β |
| Molecular effects of indoor tanning. | Gerami P et al. | β | 2025 | β |
| Molecular insights in HIV-associated cardiac dysfunction. | Valero-MuΓ±oz M et al. | β | 2025 | β |
| Multi-omic analysis of hepatocellular carcinoma reveals aberrant cis-regulatory changes and dysregulated retrotransposons with prognostic potential. | Cheng CCY et al. | β | 2025 | β |
| Multi-omics analysis of early reperfused ischemic heart reveals ERRΞ²/Ξ³ activation protects against acute myocardial infarction injury. | Gao Y et al. | β | 2025 | β |
| Multi-omics analysis reveals the effects of prenatal nutrition on carcass-related tissues in beef cattle. | Polizel GHG et al. | β | 2025 | β |
| Multi-omics-guided characterization of neoantigens improves patient stratification and potentiates combinatorial immunotherapy in glioma. | Ma Y et al. | β | 2025 | β |
| Multi-omics integration identifies diverse transcripts and chromatin accessibility profiles in Monopterus albus gonads. | Li Y et al. | β | 2025 | β |
| NAC controls nascent chain fate through tunnel sensing and chaperone action. | Lee JH et al. | β | 2025 | β |
| Near T2T haplotype-resolved genomes of cacao (Theobroma cacao) variety CCN51. | Tan H et al. | β | 2025 | β |
| NeoGuider: neoepitope prediction using advanced feature engineering. | Zhao X et al. | β | 2025 | β |
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| Noncanonical association of EZH2 with E2F1 promotes tumor proliferation through chromatin remodeling. | Yoo M et al. | β | 2025 | β |
| Non-hematopoietic erythropoietin splice variant is produced in the diseased human brain and confers neuroprotection. | Hartung T et al. | β | 2025 | β |
| Novel mutations in the RECQL4 gene affect its helicase functions, interactions with the BLM helicase and chemotherapeutics-induced cell death. | Kaczmarczyk A et al. | β | 2025 | β |
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| OmniNeo: a multi-omics pipeline incorporating proteomics and AI selection for neoantigen optimization in tumor immunotherapy. | Lu M et al. | β | 2025 | β |
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| PepQueryMHC: rapid and comprehensive tumor antigen prioritization from immunopeptidomics data. | Choi S et al. | β | 2025 | β |
| Periovulatory neurohormone dynamics reveal an association between secretoneurin and GnRH across the mouse estrous cycle. | Lu C et al. | β | 2025 | β |
| Polymorphism-driven transcriptomic changes in anthelmintic metabolism pathways of Anisakis simplex s.s. L3 larvae. | MaΕΊdziarz M et al. | β | 2025 | β |
| Protocol for evaluating RNA-protein associations in mammalian cells with RIP-seq and RIP-qPCR. | Trotman JB et al. | β | 2025 | β |
| RNA Sequencing Addresses a 5' UTR Variant Leading to X-Linked Agammaglobulinemia and Broader Immune Dysregulation. | Xu K et al. | β | 2025 | β |
| RNA transcripts in salivary extracellular vesicle cargo isolated from aged populations. | Wen S et al. | β | 2025 | β |
| Scarless circular mRNA-based CAR-T cell therapy elicits superior antitumor efficacy. | Hu Q et al. | β | 2025 | β |
| SF3B1K700E mutation in human embryonic stem cells causes aberrant expression of immune-related genes. | Dastpak M et al. | β | 2025 | β |
| SGSS05-NS3, a covalent SETD8 inhibitor that activates p53 pathway in neuroblastoma. | Liu Z et al. | β | 2025 | β |
| Signal Transducer and Activator of Transcription (STAT) Proteins Regulate Mucosal-Associated Invariant T (MAIT) Cell Function. | Cheng OJ et al. | β | 2025 | β |
| Single-cell dynamics of genome-nucleolus interactions captured by nucleolar laser microdissection (NoLMseq). | Walavalkar K et al. | β | 2025 | β |
| Single-cell RNA-seq reveals a key role for <i>Vibrio cholerae</i> Mak toxins in <i>Tetrahymena pyriformis</i> killing and bacterial survival. | Moon JM et al. | β | 2025 | β |
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| Synthetic lethality from the combination of a histone methyltransferase SUV39H2 inhibitor and a poly (ADP-ribose) polymerase inhibitor for uterine leiomyosarcoma. | Toyohara Y et al. | β | 2025 | β |
| Synthetic messenger RNA vaccines and transcriptomic dysregulation: Evidence from new-onset adverse events and cancers post-vaccination. | Von Ranke NL et al. | β | 2025 | β |
| Systems-Level Integration of Multi-Omics Identifies Genetic Modifiers of TANGO2 Deficiency Disorder. | Airoldi M et al. | β | 2025 | β |
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| Targeting ATR offers multifaceted treatment strategies involving RAD51-mediated compensatory DNA repair in bladder cancer. | Pannhausen J et al. | β | 2025 | β |
| Targeting the tumor cell-intrinsic ITGB2 axis inhibits melanoma progression. | Rasbach E et al. | β | 2025 | β |
| Temporal transcriptomic profiling reveals distinct age-associated gene expression signatures in gonads under reduced insulin/IGF-1 signaling in Caenorhabditis elegans. | Kaushik N et al. | β | 2025 | β |
| The C1QTNF6-MX2 Antiviral Axis Inhibits Porcine Circovirus Type 2 Replication in Porcine Macrophages. | Chen X et al. | β | 2025 | β |
| The Drosophila G protein-coupled receptor, GulpR, is essential for lipid mobilization in response to nutrient-limitation. | Barraza D et al. | β | 2025 | β |
| The functional regulation of protein composite nanofibers on human astrocyte for neural regeneration | Yao L et al. | β | 2025 | β |
| The Health for Life in Singapore (HELIOS) Study: delivering precision medicine research for Asian populations. | Wang X et al. | β | 2025 | β |
| The hegemonic EWSR1::ETS oncoprotein overrules core regulatory circuitry principles in Ewing sarcoma. | Grossetete S et al. | β | 2025 | β |
| The innate immune IMD pathway is a key regulator of gut microbiome and metabolic homeostasis in the black tiger shrimp (Penaeus monodon). | Supungul P et al. | β | 2025 | β |
| The ion transport, GPCR, and RTK toolkit expression in the human cerebrovascular endothelial cell line, hCMEC/D3: an Omics perspective. | Scarpellino G et al. | β | 2025 | β |
| The molecular cartography of malignant and benign sebaceous tumours. | Ferreira I et al. | β | 2025 | β |
| The Neuropeptide Neuroparsin-A Regulates the Establishment of Dominance Hierarchy in Bumblebees. | Wang H et al. | β | 2025 | β |
| The Olive Phenolic <i>S</i>-(-)-Oleocanthal as a Novel Intervention for Neuroendocrine Prostate Cancers: Therapeutic and Molecular Insights. | Tarun MTI et al. | β | 2025 | β |
| The Olive Phenolic <i>S</i>-(-)-Hydroxyoleocanthal Attenuates Neuroendocrine Prostate Cancer via Modulation of EPHA3-Centered Oncogenic Network. | Tarun MTI et al. | β | 2025 | β |
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| Transcriptomic analysis reveals light quality response and systemic nutrient allocation under monochromatic light environments in Nicotiana tabacum. | Du J et al. | β | 2025 | β |
| Transcriptomic Characterization of North Queensland Hepatocellular Carcinoma. | Gillman R et al. | β | 2025 | β |
| Transcriptomic Profiling Reveals Biphasic Regulatory Instability and Late-Stage Proteostatic Decline in Aging Mouse Oocytese. | Dinh PTN et al. | β | 2025 | β |
| Transposable Elements Regulate Tail Development and Fat Deposition in Sheep Fetuses. | Liang Q et al. | β | 2025 | β |
| Traumatic brain injury and post-injury sleep fragmentation differentially alter the microglial transcriptome. | Taylor MA et al. | β | 2025 | β |
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| Uncovering the genetic architecture of ME/CFS: a precision approach reveals impact of rare monogenic variation. | Birch CL et al. | β | 2025 | β |
| Unfolding of RNA secondary structure impairs RNA stability to fine-tune phosphate starvation responses in rice roots. | Jin Q et al. | β | 2025 | β |
| UniSplicer: A deep-learning framework for accurate splice-site prediction and splice-altering mutation detection across diverse taxa. | Hong C et al. | β | 2025 | β |
| Unmasking inflammation in juvenile dermatomyositis: myokine profiles of patients and bioengineered human muscle. | Covert LT et al. | β | 2025 | β |
| Unravelling TPX2-centered co-expression networks as key drivers of aggressive prostate cancer. | Sheibani-Tezerji R et al. | β | 2025 | β |
| Unsupervised machine learning integrates genomic variants and EMR to unravel mechanisms of brain hemorrhage and epilepsy as early indicators of Alzheimer's in down syndrome. | Liu Y et al. | β | 2025 | β |
| Unveiling the cellular and molecular mechanisms of diabetic retinopathy with human retinal organoids. | PoleΕ‘ovskΓ‘ L et al. | β | 2025 | β |
| USPPAR is a cost-effective, scalable, and highly sensitive single-cell RNA sequencing workflow compatible with diverse specimens. | Hsueh YW et al. | β | 2025 | β |
| Warmer temperature accelerates senescence by modifying the aging-dependent changes in the mosquito transcriptome, altering immunity, metabolism, and DNA repair. | Martin LE et al. | β | 2025 | β |
| Whole body regeneration deploys a rewired embryonic gene regulatory network logic. | Andreoni-Pham R et al. | β | 2025 | β |
| Whole genome circRNA profiling of <i>Withania somnifera</i> in human neuroblastoma SK-N-SH cells. | Bhaskar A et al. | β | 2025 | β |
| Wilson's disease-associated gut dysbiosis: novel insights into microbial functional alterations, virulence changes, and resistance markers. | Wei T et al. | β | 2025 | β |
| Wolbachia enhances ovarian development in the rice planthopper Laodelphax striatellus through elevated energy production. | Niu YD et al. | β | 2025 | β |