Sex and gender-related differences in alcohol use and its consequences: Contemporary knowledge and future research considerations.
paper
Cited
Public
Unavailable
- Authors
- Erol, Almila; Karpyak, Victor M
- Year
- 2015
- Journal
- Drug and alcohol dependence
- PMID
- 26371405
- DOI
- 10.1016/j.drugalcdep.2015.08.023
AIMS: To review the contemporary evidence reflecting male/female differences in alcohol use and its consequences along with the biological (sex-related) and psycho-socio-cultural (gender-related) factors associated with those differences. METHODS: MEDLINE, PubMed, Web of Science, SCOPUS, PsycINFO, and CINAHL databases were searched for relevant publications, which were subsequently screened for the presence/absence of pre-specified criteria for high quality evidence. RESULTS: Compared to men, more women are lifetime abstainers, drink less, and are less likely to engage in problem drinking, develop alcohol-related disorders or alcohol withdrawal symptoms. However, women drinking excessively develop more medical problems. Biological (sex-related) factors, including differences in alcohol pharmacokinetics as well as its effect on brain function and the levels of sex hormones may contribute to some of those differences. In addition, differences in alcohol effects on behavior may also be driven by psycho-socio-cultural (gender-related) factors. This is evident by variation in the magnitude of differences in alcohol use between countries, decreasing difference in the rates of alcohol consumption in recent generations and other findings. Evidence indicates that both sex and gender-related factors are interacting with alcohol use in complex manner, which differentially impacts the risk for development of the behavioral or medical problems and alcohol use disorders in men and women. CONCLUSIONS: Discovery of the mechanisms underlying biological (sex-related) as well as psycho-socio-cultural (gender-related) differences in alcohol use and related disorders is needed for development of personalized recommendations for prevention and treatment of alcohol use disorders and related problems in men and women.
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|---|---|---|
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| Gender as Potential Moderator of Associations Among Trauma Exposure, Posttraumatic Stress Disorder Symptoms, and Alcohol Use Disorder Symptoms in Young Adults. | Bremer-Landau JD et al. | β | 2019 | β |
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| Gender Specific Differences in Prevalence and Risk Factors for Gastro-Esophageal Reflux Disease. | Kim SY et al. | β | 2019 | β |
| Hazardous Alcohol Consumption and the Risk of Hearing Impairment in Adults Based on the Korean National Health and Nutrition Survey: A Retrospective Study. | Park JA et al. | β | 2019 | β |
| Heavy Drinking among Women Receiving Intensive Motivational Interviewing: 6-Month Outcomes. | Polcin DL et al. | β | 2019 | β |
| Heterogeneity in the Co-occurrence of Substance Use and Posttraumatic Stress Disorder: A Latent Class Analysis Approach. | Contractor AA et al. | β | 2019 | β |
| Impact of Sex and ADHD Status on Psychiatric Comorbidity in Treatment-Seeking Alcoholics. | Reyes MM et al. | β | 2019 | β |
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| Longitudinal Findings from a Randomized Clinical Trial of Varenicline for Alcohol Use Disorder with Comorbid Cigarette Smoking. | Bold KW et al. | β | 2019 | β |
| Mood Disorders and Severity of Addiction in Alcohol-Dependent Patients Could Be Mediated by Sex Differences. | Palma-Γlvarez RF et al. | β | 2019 | β |
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| Patient Sex in the Setting of Liver Transplant in Alcoholic Liver Disease. | Legaz I et al. | β | 2019 | β |
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| Sex- and Age-Related Differences in the Contribution of Ultrasound-Measured Visceral and Subcutaneous Abdominal Fat to Fatty Liver Index in Overweight and Obese Caucasian Adults. | Leone A et al. | β | 2019 | β |
| Sex difference in IgE sensitization associated with alcohol consumption in the general population. | Roh D et al. | β | 2019 | β |
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| Sex-specific association of depressive disorder and transient emotional states with alcohol consumption in male and female alcoholics. | Karpyak VM et al. | β | 2019 | β |
| Sex-specific ultrasonic vocalization patterns and alcohol consumption in high alcohol-drinking (HAD-1) rats. | Mittal N et al. | β | 2019 | β |
| Shifting Age of Peak Binge Drinking Prevalence: Historical Changes in Normative Trajectories Among Young Adults Aged 18 to 30. | Patrick ME et al. | β | 2019 | β |
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| Swiping right: Alcohol, online dating, and sexual hookups in postcollege women. | Wilhite ER et al. | β | 2019 | β |
| "..that warm feeling that [alcohol] gave me was what I interpreted love would feel like.." Lived experience of excessive alcohol use and care proceedings by mothers in the family justice system in the UK. | Boreham M et al. | β | 2019 | β |
| The Association Between Type of Sexual Assault and Post-Assault Alcohol Misuse Is Moderated by Avoidance Among Recipients of a Sexual Assault Medical Forensic Examination. | Hahn CK et al. | β | 2019 | β |
| The P300 in alcohol use disorder: A meta-analysis and meta-regression. | Hamidovic A et al. | β | 2019 | β |
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| Alcohol Consumption and Binge Drinking Among Young Adults Aged 20-30 Years in Lisbon, Portugal. | Moutinho LSM et al. | β | 2018 | β |
| Alcohol intake, ADH1B and ADH1C genotypes, and the risk of colorectal cancer by sex and subsite in the Netherlands Cohort Study. | Offermans NSM et al. | β | 2018 | β |
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| Commentary on Livingston et al. (2018): Change in gender ratios, what do they signify? | Bratberg GH et al. | β | 2018 | β |
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| Differences in alcohol consumption and drinking patterns in Ghanaians in Europe and Africa: The RODAM Study. | Addo J et al. | β | 2018 | β |
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| Ethanol-induced cognitive dysfunction is associated with alterations in the mammalian target of rapamycin signalling pathway in the hippocampus of male mice. | Xing Y et al. | β | 2018 | β |
| Ethnic Drinking Culture, Acculturation, and Enculturation in Relation to Alcohol Drinking Behavior Among Marriage-Based Male Immigrants in Taiwan. | Chen HH et al. | β | 2018 | β |
| Feminine Discrepancy Stress and Psychosocial Maladjustment Among Adolescent Girls. | Reidy DE et al. | β | 2018 | β |
| Frequent solitary drinking mediates the associations between negative affect and harmful drinking in emerging adults. | Bilevicius E et al. | β | 2018 | β |
| Fruit and Vegetable Consumption among Immigrants in Portugal: A Nationwide Cross-Sectional Study. | Costa L et al. | β | 2018 | β |
| Gender differences among Veterans with alcohol use disorder nationally in the Veterans Health Administration. | Kalpakci A et al. | β | 2018 | β |
| Gender Differences in Anxiety and Depression before and after Alcohol Detoxification: Anxiety and Depression as Gender-Related Predictors of Relapse. | Oliva F et al. | β | 2018 | β |
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| Gender-related differences in addiction: a review of human studies. | Zakiniaeiz Y et al. | β | 2018 | β |
| Gender-Specific Effects of Selection for Drinking in the Dark on the Network Roles of Coding and Noncoding RNAs. | Iancu OD et al. | β | 2018 | β |
| Identification of heavy drinking in the 10-item AUDIT: Results from a prospective study among 18-21years old non-dependent German males. | Kuitunen-Paul S et al. | β | 2018 | β |
| Lycium barbarum Polysaccharide Supplementation Improves Alcoholic Liver Injury in Female Mice by Inhibiting Stearoyl-CoA Desaturase 1. | Wang F et al. | β | 2018 | β |
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| Microglial IL-1Ξ² progressively increases with duration of alcohol consumption. | Pradier B et al. | β | 2018 | β |
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| Sex as a biological variable: Drug use and abuse. | Riley AL et al. | β | 2018 | β |
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| Studying Sex Differences in Animal Models of Addiction: An Emphasis on Alcohol-Related Behaviors. | Hilderbrand ER et al. | β | 2018 | β |
| The Association Between Alcohol Consumption, Lifetime Alcohol Use Disorder, and Psychiatric Distress Among Male and Female Veterans. | Wilson SM et al. | β | 2018 | β |
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| Utilizing an Evidence-Based Alcohol Screening Tool for Identification of Alcohol Misuse. | Miller LB et al. | β | 2018 | β |
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| Alcohol-Related Blackouts, Negative Alcohol-Related Consequences, and Motivations for Drinking Reported by Newly Matriculating Transgender College Students. | Tupler LA et al. | β | 2017 | β |
| Alcohol use from adolescence through early adulthood: an assessment of measurement invariance by age and gender. | Fish JN et al. | β | 2017 | β |
| Alcohol vapor exposure differentially impacts mesocorticolimbic cytokine expression in a sex-, region-, and duration-specific manner. | Baxter-Potter LN et al. | β | 2017 | β |
| Alignment of adherence and risk for HIV acquisition in a demonstration project of pre-exposure prophylaxis among HIV serodiscordant couples in Kenya and Uganda: a prospective analysis of prevention-effective adherence. | Haberer JE et al. | β | 2017 | β |
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| Prevalence of Polysubstance Abuse and Dual Diagnosis in Patients Admitted to Alcohol Rehabilitation Units for Alcohol-Related Problems in Italy: Changes in 15 Years. | Zambon A et al. | β | 2017 | β |
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| Sex differences in the interacting roles of impulsivity and positive alcohol expectancy in problem drinking: A structural brain imaging study. | Ide JS et al. | β | 2017 | β |
| The Effect of Computerized Physician Order Entry Template Modifications on the Administration of High-Risk Medications in Older Adults in the Emergency Department. | Kim M et al. | β | 2017 | β |
| Adolescent Women Induce Lower Blood Alcohol Levels Than Men in a Laboratory Alcohol Self-Administration Experiment. | JΓΌnger E et al. | β | 2016 | β |
| Alcohol use predicts elevation in inflammatory marker soluble CD14 in men living with HIV. | Monnig MA et al. | β | 2016 | β |
| Disability pension due to common mental disorders and subsequent suicidal behaviour: a population-based prospective cohort study. | Rahman SG et al. | β | 2016 | β |
| Epidemiology, Evolution, and Long-Term Survival of Alcoholic Cirrhosis Patients Submitted to Liver Transplantation in Southeastern Spain. | Legaz I et al. | β | 2016 | β |
| Overactivation of the Pupillary Response to Emotional Information in Short- and Long-Term Alcohol Abstinent Patients. | Claisse C et al. | β | 2016 | β |
| Sex differences in alcohol consumption and alterations in nucleus accumbens endocannabinoid mRNA in alcohol-dependent rats. | Henricks AM et al. | β | 2016 | β |
| Sex differences in substance use disorders: focus on side effects. | Agabio R et al. | β | 2016 | β |
| Sex differences in the relationship between heavy alcohol use, inhibition and performance monitoring: Disconnect between behavioural and brain functional measures. | Smith JL et al. | β | 2016 | β |
| Taking the First Full Drink: Epidemiological Evidence on Male-Female Differences in the United States. | Cheng HG et al. | β | 2016 | β |