Error rate and outcome predictability affect neural activation in prefrontal cortex and anterior cingulate during decision-making.
paper
Cited
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- Authors
- Paulus, Martin P; Hozack, Nikki; Frank, Lawrence; Brown, Gregory G
- Year
- 2002
- Journal
- NeuroImage
- PMID
- 11906224
- DOI
- 10.1006/nimg.2001.1031
Decision-making in the presence of uncertainty is a complex process that involves both affective and cognitive factors. Both error rate and predictability have been implicated in the process of response selection during decision-making. This study examined the hypothesis that the rate of errors during decision-making differentially affects the activation in prefrontal and cingulate cortex. BOLD echo-planar signal intensity was obtained during a two-choice prediction task across 90-s blocks with 20, 50, or 80% error rates. This study yielded three main findings. First, at chance level error rates, activation of the right dorsolateral (BA 9, 46), inferior prefrontal (BA 44), and precuneus (BA 7) during the two-choice prediction task replicated the finding previously reported. Second, premotor (BA 6) and parahippocampal (BA 36) areas were relatively more active at high error rates, and dorsolateral (BA 9, 46) and inferior prefrontal cortex (BA 44) as well as parietal (BA 40) and cingulate cortex (BA 25, 32) were more active during low error rates. Third, the relationship between the frequency of the dominant strategy underlying decision-making (win-stay/lose-shift) and the activation in the dorsolateral prefrontal cortex and the anterior cingulate was dependent on error rate or outcome predictability. These results support the hypothesis that error rates and predictability affect the activation patterns in the neural systems underlying decision-making because these structures maintain a representation of the reinforcement history for the available response alternatives to select an "optimal strategy."
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| Impulse Control Disorders in Parkinson's Disease: Epidemiology, Pathogenesis and Therapeutic Strategies. | Zhang JF et al. | — | 2021 | → |
| Phenotypes of reinforcement sensitivity as predictors of the response to acute antidepressant treatment in rats. | Noworyta K et al. | — | 2021 | → |
| Cooperation and Social Rules Emerging From the Principle of Surprise Minimization. | Hartwig M et al. | — | 2020 | → |
| Probing relationships between reinforcement learning and simple behavioral strategies to understand probabilistic reward learning. | Iyer ES et al. | — | 2020 | → |
| Using Transcranial Magnetic Stimulation to Test a Network Model of Perceptual Decision Making in the Human Brain. | Luber B et al. | — | 2020 | → |
| Neural reward response to substance-free activity images in opiate use disorder patients with depressive symptoms. | Yi JY et al. | — | 2019 | → |
| Reward Prediction Error Signaling during Reinforcement Learning in Social Anxiety Disorder is altered by Social Observation | Becker MPI et al. | — | 2019 | — |
| A neural biomarker, the error-related negativity, predicts the first onset of generalized anxiety disorder in a large sample of adolescent females. | Meyer A et al. | — | 2018 | → |
| Separate Neural Networks for Gains and Losses in Intertemporal Choice. | Zhang YY et al. | — | 2018 | → |
| Translational Assessments of Reward and Anhedonia: A Tribute to Athina Markou. | Der-Avakian A et al. | — | 2018 | → |
| A neural network that links brain function, white-matter structure and risky behavior. | Kohno M et al. | — | 2017 | → |
| Boys vs. girls: Gender differences in the neural development of trust and reciprocity depend on social context. | Lemmers-Jansen ILJ et al. | — | 2017 | → |
| Insular and cingulate attenuation during decision making is associated with future transition to stimulant use disorder. | Stewart JL et al. | — | 2017 | → |
| Only-child and non-only-child exhibit differences in creativity and agreeableness: evidence from behavioral and anatomical structural studies. | Yang J et al. | — | 2017 | → |
| QEEG-based neural correlates of decision making in a well-trained eight year-old chess player. | Alipour A et al. | — | 2017 | → |
| Reversal learning strategy in adolescence is associated with prefrontal cortex activation. | Boehme R et al. | — | 2017 | → |
| Uncertainty and stress: Why it causes diseases and how it is mastered by the brain. | Peters A et al. | — | 2017 | → |
| Cortical thickness changes in patients with Parkinson's disease and impulse control disorders. | Tessitore A et al. | — | 2016 | → |
| Repeated transcranial direct current stimulation reduces food craving in Wistar rats. | Macedo IC et al. | — | 2016 | → |
| Trait "pessimism" is associated with increased sensitivity to negative feedback in rats. | Rygula R et al. | — | 2016 | → |
| Attenuated Neural Processing of Risk in Young Adults at Risk for Stimulant Dependence. | Reske M et al. | — | 2015 | → |
| Semantic brain areas are involved in gesture comprehension: An electrical neuroimaging study. | Proverbio AM et al. | — | 2015 | → |
| Medial frontal cortex and anterior insula are less sensitive to outcome predictability when monetary stakes are higher. | Stern ER et al. | — | 2014 | → |
| Modelling cognitive affective biases in major depressive disorder using rodents. | Hales CA et al. | — | 2014 | → |
| Neurophysiology of performance monitoring and adaptive behavior. | Ullsperger M et al. | — | 2014 | → |
| Altered frontocingulate activation during aversive interoceptive processing in young adults transitioning to problem stimulant use. | Stewart JL et al. | — | 2013 | → |
| Increased error-related brain activity in six-year-old children with clinical anxiety. | Meyer A et al. | — | 2013 | → |
| Neural correlates of the divergence of instrumental probability distributions. | Liljeholm M et al. | — | 2013 | → |
| Relations among EEG-alpha asymmetry, BIS/BAS, and dispositional optimism. | De Pascalis V et al. | — | 2013 | → |
| Stress modulates reinforcement learning in younger and older adults. | Lighthall NR et al. | — | 2013 | → |
| Deep brain stimulation of nucleus accumbens region in alcoholism affects reward processing. | Heldmann M et al. | — | 2012 | → |
| Different varieties of uncertainty in human decision-making. | Bland AR et al. | — | 2012 | → |
| Frontopolar cortical inefficiency may underpin reward and working memory dysfunction in bipolar disorder. | Jogia J et al. | — | 2012 | → |
| Strategic control in decision-making under uncertainty. | Venkatraman V et al. | — | 2012 | → |
| The development of the error-related negativity (ERN) and its relationship with anxiety: evidence from 8 to 13 year-olds. | Meyer A et al. | — | 2012 | → |
| Medial prefrontal cortex predicts and evaluates the timing of action outcomes. | Forster SE et al. | — | 2011 | → |
| Prefrontal cortex and drug abuse vulnerability: translation to prevention and treatment interventions. | Perry JL et al. | — | 2011 | → |
| The neural substrate and functional integration of uncertainty in decision making: an information theory approach. | Goñi J et al. | — | 2011 | → |
| Uncertainty and cognitive control. | Mushtaq F et al. | — | 2011 | → |
| Abnormal strategies during visual discrimination reversal learning in ephrin-A2(-/-) mice. | Arnall S et al. | — | 2010 | → |
| Dysfunctional reward processing in male alcoholics: an ERP study during a gambling task. | Kamarajan C et al. | — | 2010 | → |
| Error effects in anterior cingulate cortex reverse when error likelihood is high. | Jessup RK et al. | — | 2010 | → |
| From bad to worse: striatal coding of the relative value of painful decisions. | Brooks AM et al. | — | 2010 | → |
| Neuronal and cognitive plasticity: a neurocognitive framework for ameliorating cognitive aging. | Greenwood PM et al. | — | 2010 | → |
| Psychopathy, frustration, and reactive aggression: the role of ventromedial prefrontal cortex. | Blair RJ | — | 2010 | → |
| Serotonin modulates sensitivity to reward and negative feedback in a probabilistic reversal learning task in rats. | Bari A et al. | — | 2010 | → |
| The development of performance-monitoring function in the posterior medial frontal cortex. | Fitzgerald KD et al. | — | 2010 | → |
| Development of anterior cingulate functional connectivity from late childhood to early adulthood. | Kelly AM et al. | — | 2009 | → |
| Judgment in Older Adults with Normal Cognition, Cognitive Complaints, MCI, and Mild AD: Relation to Regional Frontal Gray Matter. | Rabin LA et al. | — | 2009 | → |
| Neural mechanism of intertemporal choice: from discounting future gains to future losses. | Xu L et al. | — | 2009 | → |
| Resolving response, decision, and strategic control: evidence for a functional topography in dorsomedial prefrontal cortex. | Venkatraman V et al. | — | 2009 | → |
| The effects of fetal alcohol syndrome on response execution and inhibition: an event-related potential study. | Burden MJ et al. | — | 2009 | → |
| When is an error not a prediction error? An electrophysiological investigation. | Holroyd CB et al. | — | 2009 | → |
| Reduced behavioral and neural activation in stimulant users to different error rates during decision making. | Paulus MP et al. | — | 2008 | → |
| Adults with autism show increased sensitivity to outcomes at low error rates during decision-making. | Minassian A et al. | — | 2007 | → |
| Cortical representation of verb processing in sentence comprehension: number of complements, subcategorization, and thematic frames. | Shetreet E et al. | — | 2007 | → |
| Dissociable but inter-related systems of cognitive control and reward during decision making: evidence from pupillometry and event-related fMRI. | Satterthwaite TD et al. | — | 2007 | → |
| Dynamics of oscillatory activity during auditory decision making. | Kaiser J et al. | — | 2007 | → |
| Dysfunctions of medial and lateral orbitofrontal cortex in psychopathy. | Blair RJ | — | 2007 | → |
| EEG-informed fMRI reveals spatiotemporal characteristics of perceptual decision making. | Philiastides MG et al. | — | 2007 | → |
| Impulsivity, neural deficits, and the addictions: the "oops" factor in relapse. | Adinoff B et al. | — | 2007 | → |
| Probabilistic reversal learning impairments in schizophrenia: further evidence of orbitofrontal dysfunction. | Waltz JA et al. | — | 2007 | → |
| Risk prediction and aversion by anterior cingulate cortex. | Brown JW et al. | — | 2007 | → |
| The influences of task difficulty and response correctness on neural systems supporting fluid reasoning. | Kalbfleisch ML et al. | — | 2007 | → |
| Time-frequency intracranial source localization of feedback-related EEG activity in hypothesis testing. | Papo D et al. | — | 2007 | → |
| Alcohol attentional bias: drinking salience or cognitive impairment? | Fadardi JS et al. | — | 2006 | → |
| A neural representation of categorization uncertainty in the human brain. | Grinband J et al. | — | 2006 | → |
| An fMRI examination of developmental differences in the neural correlates of uncertainty and decision-making. | Krain AL et al. | — | 2006 | → |
| Behavioral, but not reward, risk modulates activation of prefrontal, parietal, and insular cortices. | Huettel SA | — | 2006 | → |
| Distinct neural mechanisms of risk and ambiguity: a meta-analysis of decision-making. | Krain AL et al. | — | 2006 | → |
| Increased error-related negativity (ERN) in childhood anxiety disorders: ERP and source localization. | Ladouceur CD et al. | — | 2006 | → |
| Neural correlates of developmental differences in risk estimation and feedback processing. | van Leijenhorst L et al. | — | 2006 | → |
| Neural correlates of spatial working memory in humans: a functional magnetic resonance imaging study comparing visual and tactile processes. | Ricciardi E et al. | — | 2006 | → |
| Neural representation of task difficulty and decision making during perceptual categorization: a timing diagram. | Philiastides MG et al. | — | 2006 | → |
| Neural signatures of economic preferences for risk and ambiguity. | Huettel SA et al. | — | 2006 | → |
| Odor identification accuracy declines following 24 h of sleep deprivation. | Killgore WD et al. | — | 2006 | → |
| Social and emotional functions in three patients with medial frontal lobe damage including the anterior cingulate cortex. | Baird A et al. | — | 2006 | → |
| The neural basis of social tactics: An fMRI study. | Fukui H et al. | — | 2006 | → |
| Anterior cingulate activity during error and autonomic response. | Critchley HD et al. | — | 2005 | → |
| Maturation of action monitoring from adolescence to adulthood: an ERP study. | Hogan AM et al. | — | 2005 | → |
| Risky decision making and the anterior cingulate cortex in abstinent drug abusers and nonusers. | Fishbein DH et al. | — | 2005 | → |
| A functional neuroimaging study of motivation and executive function. | Taylor SF et al. | — | 2004 | → |
| Anterior cingulate activation in high trait anxious subjects is related to altered error processing during decision making. | Paulus MP et al. | — | 2004 | → |
| Anterior cingulate dysfunction during choice anticipation in schizophrenia. | Quintana J et al. | — | 2004 | → |
| Complex decision-making in early childhood. | Garon N et al. | — | 2004 | → |
| Distinct portions of anterior cingulate cortex and medial prefrontal cortex are activated by reward processing in separable phases of decision-making cognition. | Rogers RD et al. | — | 2004 | → |
| Neurocognitive mechanisms of cognitive control: the role of prefrontal cortex in action selection, response inhibition, performance monitoring, and reward-based learning. | Ridderinkhof KR et al. | — | 2004 | → |
| Parametric study of accuracy and response time in schizophrenic persons making visual or auditory discriminations. | Holcomb HH et al. | — | 2004 | → |
| PET study of brain maintenance of verbal creative activity. | Bechtereva NP et al. | — | 2004 | → |
| Practice, learning, and the likelihood of making an error: how task experience shapes physiological response in patients with schizophrenia. | Holcomb HH | — | 2004 | → |
| The relevance of behavioural measures for functional-imaging studies of cognition. | Wilkinson D et al. | — | 2004 | → |
| Why am I unsure? Internal and external attributions of uncertainty dissociated by fMRI. | Volz KG et al. | — | 2004 | → |
| Decision making by methamphetamine-dependent subjects is associated with error-rate-independent decrease in prefrontal and parietal activation. | Paulus MP et al. | — | 2003 | → |
| Error-rate-related caudate and parietal cortex activation during decision making. | Verney SP et al. | — | 2003 | → |
| Predicting events of varying probability: uncertainty investigated by fMRI. | Volz KG et al. | — | 2003 | → |
| Schizophrenia subjects show intact success-related neural activation but impaired uncertainty processing during decision-making. | Paulus MP et al. | — | 2003 | → |