A navigator for human genome epidemiology.
paper
Cited
Public
Unavailable
- Authors
- Yu, Wei; Gwinn, Marta; Clyne, Melinda; Yesupriya, Ajay; Khoury, Muin J
- Year
- 2008
- Journal
- Nature genetics
- PMID
- 18227866
- DOI
- 10.1038/ng0208-124
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| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Copy Number Variation in Asthma: An Integrative Review. | Garcia FM et al. | β | 2025 | β |
| DNA Methylation Biomarkers Predict Offspring Metabolic Risk From Mothers With Hyperglycemia in Pregnancy. | Assaf J et al. | β | 2025 | β |
| High-throughput transcriptome analysis reveals a developmental increase in Acvr1c which mediates epigenetic repression of the gene encoding the pubertal brake, Makorin ring finger protein 3. | Shalev D et al. | β | 2025 | β |
| NDDRF 2.0: An update and expansion of risk factor knowledge base for personalized prevention of neurodegenerative diseases. | Bi C et al. | β | 2025 | β |
| Advances in Parkinson's disease research - A computational network pharmacological approach. | Akki AJ et al. | β | 2024 | β |
| A Network and Pathway Analysis of Genes Associated With Atrial Fibrillation. | Zeng M et al. | β | 2024 | β |
| Bioinformatics Prediction for Network-Based Integrative Multi-Omics Expression Data Analysis in Hirschsprung Disease. | Lucena-Padros H et al. | β | 2024 | β |
| From bench to in silico and backwards: What have we done on genetics of recurrent pregnancy loss and implantation failure and where should we go next? | Gomes FG et al. | β | 2024 | β |
| Identification of Potentially Repurposable Drugs for Lewy Body Dementia Using a Network-Based Approach. | Manoj M et al. | β | 2024 | β |
| Innovative target mining stratagems to navigate drug repurposing endeavours. | Saravanan KS et al. | β | 2024 | β |
| Modeling Path Importance for Effective Alzheimer's Disease Drug Repurposing. | Xiang S et al. | β | 2024 | β |
| Network Medicine: A Potential Approach for Virtual Drug Screening. | Ma M et al. | β | 2024 | β |
| Bioinformatic approach for repurposing immunomodulatory drugs for lepromatous leprosy. | Espitia GJ et al. | β | 2023 | β |
| A comprehensive review of artificial intelligence and network based approaches to drug repurposing in Covid-19. | Ahmed F et al. | β | 2022 | β |
| Analysis of SOD1 and C9orf72 mutations in patients with amyotrophic lateral sclerosis in Antioquia, Colombia | Jaramillo J et al. | β | 2022 | β |
| Benchmark data set for breast cancer associated genes. | Raj S et al. | β | 2022 | β |
| DNA methylation as a potential mediator of the association between prenatal tobacco and alcohol exposure and child neurodevelopment in a South African birth cohort. | Abrishamcar S et al. | β | 2022 | β |
| Exploration of the System-Level Mechanisms of the Herbal Drug FDY003 for Pancreatic Cancer Treatment: A Network Pharmacological Investigation. | Lee HS et al. | β | 2022 | β |
| Identification of Potential Repurposable Drugs in Alzheimer's Disease Exploiting a Bioinformatics Analysis. | Fiscon G et al. | β | 2022 | β |
| Investigation of Anti-Liver Cancer Activity of the Herbal Drug FDY003 Using Network Pharmacology. | Lee HS et al. | β | 2022 | β |
| Jiawei Runjing Decoction Improves Spermatogenesis of Cryptozoospermia With Varicocele by Regulating the Testicular Microenvironment: Two-Center Prospective Cohort Study. | Liu H et al. | β | 2022 | β |
| A Network Pharmacology Study on the Molecular Mechanisms of FDY003 for Breast Cancer Treatment. | Lee HS et al. | β | 2021 | β |
| Approaches for network based drug discovery. | Jayachandran P et al. | β | 2021 | β |
| A unique neurogenomic state emerges after aggressive confrontations in males of the fish Betta splendens. | Vu TD et al. | β | 2021 | β |
| Differential Associations of SLCO Transporters with Prostate Cancer Aggressiveness between African Americans and European Americans. | Tang L et al. | β | 2021 | β |
| DNA methylation and noncoding RNA in OA: Recent findings and methodological advances. | Izda V et al. | β | 2021 | β |
| Emerging Molecular Dependencies of Mutant EGFR-Driven Non-Small Cell Lung Cancer. | Farnsworth DA et al. | β | 2021 | β |
| Exploring complex and heterogeneous correlations on hypergraph for the prediction of drug-target interactions. | Ruan D et al. | β | 2021 | β |
| Genetic Variants in <i>COX2</i> and <i>ALOX</i> Genes and Breast Cancer Risk in White and Black Women. | Mongiovi JM et al. | β | 2021 | β |
| Network module-based drug repositioning for pulmonary arterial hypertension. | Wang RS et al. | β | 2021 | β |
| Prediction of Synergistic Drug Combinations for Prostate Cancer by Transcriptomic and Network Characteristics. | Li S et al. | β | 2021 | β |
| SAveRUNNER: A network-based algorithm for drug repurposing and its application to COVID-19. | Fiscon G et al. | β | 2021 | β |
| Uncovering the Anti-Lung-Cancer Mechanisms of the Herbal Drug FDY2004 by Network Pharmacology. | Lee HS et al. | β | 2021 | β |
| An Investigation of the Molecular Mechanisms Underlying the Analgesic Effect of Jakyak-Gamcho Decoction: A Network Pharmacology Study. | Lee HS et al. | β | 2020 | β |
| Discovery of inflammatory bowel disease-associated miRNAs using a novel bipartite clustering approach. | Altaf-Ul-Amin M et al. | β | 2020 | β |
| Epidemiology and Genetics of Preserved Ratio Impaired SpiroMetry (PRISm): An Analysis of UK Biobank | Higbee D et al. | β | 2020 | β |
| Epidemiology, genetic epidemiology and Mendelian randomisation: more need than ever to attend to detail. | Sheehan NA et al. | β | 2020 | β |
| Lung Development Genes and Adult Lung Function. | Portas L et al. | β | 2020 | β |
| Network Pharmacology-Based Investigation of the System-Level Molecular Mechanisms of the Hematopoietic Activity of Samul-Tang, a Traditional Korean Herbal Formula. | Lee HS et al. | β | 2020 | β |
| Target identification among known drugs by deep learning from heterogeneous networks. | Zeng X et al. | β | 2020 | β |
| The genetic risk for hypertension is lower among the Hungarian Roma population compared to the general population. | SoltΓ©sz B et al. | β | 2020 | β |
| A network-based approach to uncover microRNA-mediated disease comorbidities and potential pathobiological implications. | Jin S et al. | β | 2019 | β |
| A Novel Computational Model for Predicting microRNA-Disease Associations Based on Heterogeneous Graph Convolutional Networks. | Li C et al. | β | 2019 | β |
| Comorbidity of asthma and hypertension may be mediated by shared genetic dysregulation and drug side effects. | Zolotareva O et al. | β | 2019 | β |
| Conformational Dynamics and Allosteric Regulation Landscapes of Germline PTEN Mutations Associated with Autism Compared to Those Associated with Cancer. | Smith IN et al. | β | 2019 | β |
| Fine-mapping of 98 obesity loci in Mexican children. | Liu HY et al. | β | 2019 | β |
| <i>In silico</i> Identification and Mechanism Exploration of Hepatotoxic Ingredients in Traditional Chinese Medicine. | Wu Q et al. | β | 2019 | β |
| Integrative transcriptome imputation reveals tissue-specific and shared biological mechanisms mediating susceptibility to complex traits. | Zhang W et al. | β | 2019 | β |
| Prediction of the allergic mechanism of haptens via a reaction-substructure-compound-target-pathway network system. | Di P et al. | β | 2019 | β |
| Shared Genetic Etiology of Hwabyung (Anger Syndrome) and Somatization Symptoms in South Korean Adolescent and Young Adult Twins. | Hur YM et al. | β | 2019 | β |
| The interaction effect of angiogenesis and endothelial dysfunction-related gene variants increases the susceptibility of recurrent pregnancy loss. | Trifonova EA et al. | β | 2019 | β |
| Tracking human genes along the translational continuum. | Lee K et al. | β | 2019 | β |
| A Computational Systems Pharmacology Approach to Investigate Molecular Mechanisms of Herbal Formula Tian-Ma-Gou-Teng-Yin for Treatment of Alzheimer's Disease. | Wang T et al. | β | 2018 | β |
| Age at puberty and risk of asthma: A Mendelian randomisation study. | Minelli C et al. | β | 2018 | β |
| A Network-Biology Informed Computational Drug Repositioning Strategy to Target Disease Risk Trajectories and Comorbidities of Peripheral Artery Disease. | Shameer K et al. | β | 2018 | β |
| An integrative network-based approach to identify novel disease genes and pathways: a case study in the context of inflammatory bowel disease. | Eguchi R et al. | β | 2018 | β |
| A personalized, multiomics approach identifies genes involved in cardiac hypertrophy and heart failure. | Santolini M et al. | β | 2018 | β |
| At the Crossroads Between Neurodegeneration and Cancer: A Review of Overlapping Biology and Its Implications. | Houck AL et al. | β | 2018 | β |
| Genome-wide association studies of albuminuria: towards genetic stratification in diabetes? | Pattaro C | β | 2018 | β |
| Network-based approach to prediction and population-based validation of in silico drug repurposing. | Cheng F et al. | β | 2018 | β |
| Network-Based Methods for Prediction of Drug-Target Interactions. | Wu Z et al. | β | 2018 | β |
| Repurposing sertraline sensitizes non-small cell lung cancer cells to erlotinib by inducing autophagy. | Jiang X et al. | β | 2018 | β |
| Systematic analyses of drugs and disease indications in RepurposeDB reveal pharmacological, biological and epidemiological factors influencing drug repositioning. | Shameer K et al. | β | 2018 | β |
| Transactions Between Substance Use Intervention, the Oxytocin Receptor (OXTR) Gene, and Peer Substance Use Predicting Youth Alcohol Use. | Cleveland HH et al. | β | 2018 | β |
| Association between age at menarche and cardiovascular disease: A systematic review on risk and potential mechanisms. | Luijken J et al. | β | 2017 | β |
| Casting the critical regions in nucleotide binding oligomerization domain 2 protein: a signature mediated structural dynamics approach. | Raghuraman P et al. | β | 2017 | β |
| Cervical Carcinogenesis and Immune Response Gene Polymorphisms: A Review. | Mehta AM et al. | β | 2017 | β |
| Genetic contribution to lipid levels in early life based on 158 loci validated in adults: the FAMILY study. | Christie S et al. | β | 2017 | β |
| Genetic Polymorphisms of Hemostatic Factors and Thrombotic Risk in Non <i>BCR</i>-<i>ABL</i> Myeloproliferative Neoplasms: A Pilot Study. | DambrauskienΔ R et al. | β | 2017 | β |
| Genetic variants involved in oxidative stress, base excision repair, DNA methylation, and folate metabolism pathways influence myeloid neoplasias susceptibility and prognosis. | GonΓ§alves AC et al. | β | 2017 | β |
| Genome-wide association study of sepsis in extremely premature infants. | Srinivasan L et al. | β | 2017 | β |
| Insights into the molecular mechanisms of Polygonum multiflorum Thunb-induced liver injury: a computational systems toxicology approach. | Wang YY et al. | β | 2017 | β |
| In silico search for modifier genes associated with pancreatic and liver disease in Cystic Fibrosis. | TrouvΓ© P et al. | β | 2017 | β |
| LiverWiki: a wiki-based database for human liver. | Chen T et al. | β | 2017 | β |
| Polymorphism of the <i>ADRB2</i> Rs1042713 Gene is not Associated with Spontaneous Preterm Birth: Analyses in a Slovenian Sample and Meta Analysis. | A P et al. | β | 2017 | β |
| Quantitative and Systems Pharmacology. 1. In Silico Prediction of Drug-Target Interactions of Natural Products Enables New Targeted Cancer Therapy. | Fang J et al. | β | 2017 | β |
| SNPPhenA: a corpus for extracting ranked associations of single-nucleotide polymorphisms and phenotypes from literature. | Bokharaeian B et al. | β | 2017 | β |
| The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog). | MacArthur J et al. | β | 2017 | β |
| A knowledge base for tracking the impact of genomics on population health. | Yu W et al. | β | 2016 | β |
| Allele Frequencies of the Single Nucleotide Polymorphisms Related to the Body Burden of Heavy Metals in the Korean Population and Their Ethnic Differences. | Eom SY et al. | β | 2016 | β |
| Association between Age and the 7 Repeat Allele of the Dopamine D4 Receptor Gene. | Szekely A et al. | β | 2016 | β |
| Association of Forced Vital Capacity with the Developmental Gene NCOR2. | Minelli C et al. | β | 2016 | β |
| Association of Vitamin D Receptor Polymorphism with Susceptibility to Symptomatic Pertussis. | Han WG et al. | β | 2016 | β |
| A web resource for mining HLA associations with adverse drug reactions: HLA-ADR. | Ghattaoraya GS et al. | β | 2016 | β |
| Beyond accuracy: creating interoperable and scalable text-mining web services. | Wei CH et al. | β | 2016 | β |
| Deep resequencing of 131 Crohn's disease associated genes in pooled DNA confirmed three reported variants and identified eight novel variants. | Hong SN et al. | β | 2016 | β |
| Evolutionary triangulation: informing genetic association studies with evolutionary evidence. | Huang M et al. | β | 2016 | β |
| Explaining the disease phenotype of intergenic SNP through predicted long range regulation. | Chen J et al. | β | 2016 | β |
| Gene-set activity toolbox (GAT): A platform for microarray-based cancer diagnosis using an integrative gene-set analysis approach. | Engchuan W et al. | β | 2016 | β |
| Genome-Wide DNA Methylation Study Identifies Significant Epigenomic Changes in Osteoarthritic Subchondral Bone and Similarity to Overlying Cartilage. | Jeffries MA et al. | β | 2016 | β |
| Genome-Wide Methylation Study Identifies an IL-13-induced Epigenetic Signature in Asthmatic Airways. | Nicodemus-Johnson J et al. | β | 2016 | β |
| Genome-wide prediction and functional characterization of the genetic basis of autism spectrum disorder. | Krishnan A et al. | β | 2016 | β |
| Genomic Test Results and the Courtroom: The Roles of Experts and Expert Testimony. | Ramos E et al. | β | 2016 | β |
| GWASdb v2: an update database for human genetic variants identified by genome-wide association studies. | Li MJ et al. | β | 2016 | β |
| In silico dissection of miRNA targetome polymorphisms and their role in regulating miRNA-mediated gene expression in esophageal cancer. | Nariman-Saleh-Fam Z et al. | β | 2016 | β |
| In silico prediction of chemical mechanism of action via an improved network-based inference method. | Wu Z et al. | β | 2016 | β |
| Linkage and association analysis of circulating vitamin D and parathyroid hormone identifies novel loci in Alaska Native Yup'ik people. | Aslibekyan S et al. | β | 2016 | β |
| Network Analysis of Human Genes Influencing Susceptibility to Mycobacterial Infections. | Lipner EM et al. | β | 2016 | β |
| Semantics based approach for analyzing disease-target associations. | Kaalia R et al. | β | 2016 | β |
| Single-cell RNA sequencing identifies diverse roles of epithelial cells in idiopathic pulmonary fibrosis. | Xu Y et al. | β | 2016 | β |
| The harmonizome: a collection of processed datasets gathered to serve and mine knowledge about genes and proteins. | Rouillard AD et al. | β | 2016 | β |
| The landscape of copy number variations in Finnish families with autism spectrum disorders. | Kanduri C et al. | β | 2016 | β |
| ADHD & Pharmacotherapy: Past, Present and Future: A Review of the Changing Landscape of Drug Therapy for Attention Deficit Hyperactivity Disorder. | Connolly JJ et al. | β | 2015 | β |
| AMPK/HuR-Driven IL-20 Post-Transcriptional Regulation in Psoriatic Skin. | Garcin G et al. | β | 2015 | β |
| A systematic appraisal of field synopses in genetic epidemiology: a HuGE review. | Belbasis L et al. | β | 2015 | β |
| Chinese Herbal Preparation Xuebijing Potently Inhibits Inflammasome Activation in Hepatocytes and Ameliorates Mouse Liver Ischemia-Reperfusion Injury. | Liu X et al. | β | 2015 | β |
| Clinically relevant genetic biomarkers from the brain in alcoholism with representation on high resolution chromosome ideograms. | Manzardo AM et al. | β | 2015 | β |
| Decreased plasma levels of neureglin-1 in drug naΓ―ve patients and chronic patients with schizophrenia. | Wang R et al. | β | 2015 | β |
| Discovering transnosological molecular basis of human brain diseases using biclustering analysis of integrated gene expression data. | Cha K et al. | β | 2015 | β |
| Drosophila and Caenorhabditis elegans as Discovery Platforms for Genes Involved in Human Alcohol Use Disorder. | Grotewiel M et al. | β | 2015 | β |
| Epigenetic regulation in biopsychosocial pathways. | Litzelman K et al. | β | 2015 | β |
| Forward Individualized Medicine from Personal Genomes to Interactomes. | Zhang X et al. | β | 2015 | β |
| FXR antagonism of NSAIDs contributes to drug-induced liver injury identified by systems pharmacology approach. | Lu W et al. | β | 2015 | β |
| Genetic variants in one-carbon metabolism genes and breast cancer risk in European American and African American women. | Gong Z et al. | β | 2015 | β |
| Germline oncopharmacogenetics, a promising field in cancer therapy. | Pesenti C et al. | β | 2015 | β |
| Linkage and association analysis of obesity traits reveals novel loci and interactions with dietary n-3 fatty acids in an Alaska Native (Yup'ik) population. | Vaughan LK et al. | β | 2015 | β |
| Protective effect of Daming capsule against chronic cerebral ischemia. | Song X et al. | β | 2015 | β |
| The Human Genome Project, and recent advances in personalized genomics. | Wilson BJ et al. | β | 2015 | β |
| VaDE: a manually curated database of reproducible associations between various traits and human genomic polymorphisms. | Nagai Y et al. | β | 2015 | β |
| A literature search tool for intelligent extraction of disease-associated genes. | Jung JY et al. | β | 2014 | β |
| Assessing the quality of studies supporting genetic susceptibility and outcomes of ARDS. | Acosta-Herrera M et al. | β | 2014 | β |
| Assessment of osteoarthritis candidate genes in a meta-analysis of nine genome-wide association studies. | Rodriguez-Fontenla C et al. | β | 2014 | β |
| A whole genome SNP genotyping by DNA microarray and candidate gene association study for kidney stone disease. | Rungroj N et al. | β | 2014 | β |
| Bayesian systems-based genetic association analysis with effect strength estimation and omic wide interpretation: a case study in rheumatoid arthritis. | HullΓ‘m G et al. | β | 2014 | β |
| Cellular dissection of psoriasis for transcriptome analyses and the post-GWAS era. | Swindell WR et al. | β | 2014 | β |
| Cytokine and cytokine receptor genes of the adaptive immune response are differentially associated with breast cancer risk in American women of African and European ancestry. | Quan L et al. | β | 2014 | β |
| Dietary iron, iron homeostatic gene polymorphisms and the risk of advanced colorectal adenoma and cancer. | Ruder EH et al. | β | 2014 | β |
| Editorial: Updated guidance on human genome epidemiology (HuGE) reviews and meta-analyses of genetic associations. | Gwinn M et al. | β | 2014 | β |
| FLAGS, frequently mutated genes in public exomes. | Shyr C et al. | β | 2014 | β |
| Genetic polymorphisms in oxidative stress-related genes are associated with outcomes following treatment for aggressive B-cell non-Hodgkin lymphoma. | Gustafson HL et al. | β | 2014 | β |
| Genetic risk assessment for cardiovascular disease with seven genes associated with plasma C-reactive protein concentrations in Asian populations. | Hong EP et al. | β | 2014 | β |
| Genome-wide polygenic scoring for a 14-year long-term average depression phenotype. | Chang SC et al. | β | 2014 | β |
| Host genetics and parasitic infections. | Mangano VD et al. | β | 2014 | β |
| IGENT: efficient entropy based algorithm for genome-wide gene-gene interaction analysis. | Kwon MS et al. | β | 2014 | β |
| Insights into pathophysiology of dystropy through the analysis of gene networks: an example of bronchial asthma and tuberculosis. | Bragina EY et al. | β | 2014 | β |
| Integrating genetics and social science: genetic risk scores. | Belsky DW et al. | β | 2014 | β |
| Integrative clinical transcriptomics analyses for new therapeutic intervention strategies: a psoriasis case study. | Qu XA et al. | β | 2014 | β |
| KRLMM: an adaptive genotype calling method for common and low frequency variants. | Liu R et al. | β | 2014 | β |
| Large-scale modeling of condition-specific gene regulatory networks by information integration and inference. | Ellwanger DC et al. | β | 2014 | β |
| Linking polymorphic p53 response elements with gene expression in airway epithelial cells of smokers and cancer risk. | Wang X et al. | β | 2014 | β |
| Maternal genotype and severe preeclampsia: a HuGE review. | Fong FM et al. | β | 2014 | β |
| microPIR2: a comprehensive database for human-mouse comparative study of microRNA-promoter interactions. | Piriyapongsa J et al. | β | 2014 | β |
| MicroRNA and noncoding RNA-related data sources. | Arrigo P | β | 2014 | β |
| Multi-omic landscape of rheumatoid arthritis: re-evaluation of drug adverse effects. | Tieri P et al. | β | 2014 | β |
| Multiplex sequencing of pooled mitochondrial genomes-a crucial step toward biodiversity analysis using mito-metagenomics. | Tang M et al. | β | 2014 | β |
| Network-based association of hypoxia-responsive genes with cardiovascular diseases. | Wang RS et al. | β | 2014 | β |
| Network signatures link hepatic effects of anti-diabetic interventions with systemic disease parameters. | Kelder T et al. | β | 2014 | β |
| Neurodevelopmental disorders associated with dosage imbalance of ZBTB20 correlate with the morbidity spectrum of ZBTB20 candidate target genes. | Rasmussen MB et al. | β | 2014 | β |
| Pharmacogenomic assessment of cisplatin-based chemotherapy outcomes in ovarian cancer. | Khrunin AV et al. | β | 2014 | β |
| Single-Nucleotide Polymorphisms Within MicroRNAs Sequences and Their 3' UTR Target Sites May Regulate Gene Expression in Gastrointestinal Tract Cancers. | Saadatian Z et al. | β | 2014 | β |
| Study of five novel non-synonymous polymorphisms in human brain-expressed genes in a Colombian sample. | Ojeda DA et al. | β | 2014 | β |
| Text mining in cancer gene and pathway prioritization. | Luo Y et al. | β | 2014 | β |
| The 5-HTTLPR polymorphism, early and recent life stress, and cognitive endophenotypes of depression. | Kruijt AW et al. | β | 2014 | β |
| Variants of estrogen-related genes and breast cancer risk in European and African American women. | Quan L et al. | β | 2014 | β |
| A common variant highly associated with plasma VEGFA levels also contributes to the variation of both LDL-C and HDL-C. | Stathopoulou MG et al. | β | 2013 | β |
| A database for curating the associations between killer cell immunoglobulin-like receptors and diseases in worldwide populations. | Takeshita LY et al. | β | 2013 | β |
| Assessment of systematic effects of methodological characteristics on candidate genetic associations. | Aljasir B et al. | β | 2013 | β |
| Association between three genetic variants of the Perilipin Gene (PLIN) and glucose metabolism: results from a replication study among Chinese adults and a meta-analysis. | Yu D et al. | β | 2013 | β |
| Associations of ATR and CHEK1 single nucleotide polymorphisms with breast cancer. | Lin WY et al. | β | 2013 | β |
| Development and evaluation of a genetic risk score for obesity. | Belsky DW et al. | β | 2013 | β |
| Evidence for novel genetic loci associated with metabolic traits in Yup'ik people. | Aslibekyan S et al. | β | 2013 | β |
| Functional CYP1A1 genetic variants, alone and in combination with smoking, contribute to development of head and neck cancers. | Liu L et al. | β | 2013 | β |
| Gene-environment interactions in cancer epidemiology: a National Cancer Institute Think Tank report. | Hutter CM et al. | β | 2013 | β |
| Genetics and heritability of cervical spondylotic myelopathy and ossification of the posterior longitudinal ligament: results of a systematic review. | Wilson JR et al. | β | 2013 | β |
| Genetic variants and the risk of gestational diabetes mellitus: a systematic review. | Zhang C et al. | β | 2013 | β |
| Genome-wide association study meta-analysis reveals transethnic replication of mean arterial and pulse pressure loci. | Kelly TN et al. | β | 2013 | β |
| Haplotype structure enables prioritization of common markers and candidate genes in autism spectrum disorder. | Vardarajan BN et al. | β | 2013 | β |
| High trans-ethnic replicability of GWAS results implies common causal variants. | Marigorta UM et al. | β | 2013 | β |
| Identification of genetic associations of SP110/MYBBP1A/RELA with pulmonary tuberculosis in the Chinese Han population. | Cai L et al. | β | 2013 | β |
| Importance of different types of prior knowledge in selecting genome-wide findings for follow-up. | Minelli C et al. | β | 2013 | β |
| Innate immunity pathways and breast cancer Risk in African American and European-American women in the Women's Circle of Health Study (WCHS). | Gong Z et al. | β | 2013 | β |
| Insights into TREM2 biology by network analysis of human brain gene expression data. | Forabosco P et al. | β | 2013 | β |
| Large numbers of genetic variants considered to be pathogenic are common in asymptomatic individuals. | Cassa CA et al. | β | 2013 | β |
| LiverAtlas: a unique integrated knowledge database for systems-level research of liver and hepatic disease. | Zhang Y et al. | β | 2013 | β |
| MNS16A tandem repeats minisatellite of human telomerase gene and cancer risk: a meta-analysis. | Xia X et al. | β | 2013 | β |
| Modernizing the systematic review process to inform comparative effectiveness: tools and methods. | Wallace BC et al. | β | 2013 | β |
| Multi-dimensional prioritization of dental caries candidate genes and its enriched dense network modules. | Wang Q et al. | β | 2013 | β |
| PriVar: a toolkit for prioritizing SNVs and indels from next-generation sequencing data. | Zhang L et al. | β | 2013 | β |
| Progress and future aspects in genetics of human hypertension. | Zhao Q et al. | β | 2013 | β |
| Prophylactic vaccination with adjuvant monophosphoryl lipid a prevents Th2-mediated murine asthmatic responses. | Wu CJ et al. | β | 2013 | β |
| PUMA: a unified framework for penalized multiple regression analysis of GWAS data. | Hoffman GE et al. | β | 2013 | β |
| RAvariome: a genetic risk variants database for rheumatoid arthritis based on assessment of reproducibility between or within human populations. | Nagai Y et al. | β | 2013 | β |
| The geometric increase in meta-analyses from China in the genomic era. | Ioannidis JP et al. | β | 2013 | β |
| Three multiplex snapshot assays for SNP genotyping in candidate innate immune genes. | Esteves LM et al. | β | 2013 | β |
| Translational potential into health care of basic genomic and genetic findings for human immunodeficiency virus, Chlamydia trachomatis, and human papilloma virus. | Malogajski J et al. | β | 2013 | β |
| Use of genomic panels to determine risk of developing type 2 diabetes in the general population: a targeted evidence-based review. | Palomaki GE et al. | β | 2013 | β |
| Ablation of serum response factor in dopaminergic neurons exacerbates susceptibility towards MPTP-induced oxidative stress. | Rieker C et al. | β | 2012 | β |
| ALFRED: an allele frequency resource for research and teaching. | Rajeevan H et al. | β | 2012 | β |
| Analysis of association between common SNPs in ErbB4 and bipolar affective disorder, major depressive disorder and schizophrenia in the Han Chinese population. | Chen P et al. | β | 2012 | β |
| A public resource facilitating clinical use of genomes. | Ball MP et al. | β | 2012 | β |
| Association between IL6 -174G/C and cancer: A meta-analysis of 105,482 individuals. | Liu RY et al. | β | 2012 | β |
| Autworks: a cross-disease network biology application for Autism and related disorders. | Nelson TH et al. | β | 2012 | β |
| A vector space model approach to identify genetically related diseases. | Sarkar IN | β | 2012 | β |
| Convergence of genome-wide association and candidate gene studies for alcoholism. | Olfson E et al. | β | 2012 | β |
| FGFR2 is associated with bipolar disorder: a large-scale case-control study of three psychiatric disorders in the Chinese Han population. | Wang T et al. | β | 2012 | β |
| Gene-environment interactions in asthma and allergic diseases: challenges and perspectives. | Kauffmann F et al. | β | 2012 | β |
| GWASdb: a database for human genetic variants identified by genome-wide association studies. | Li MJ et al. | β | 2012 | β |
| iLOCi: a SNP interaction prioritization technique for detecting epistasis in genome-wide association studies. | Piriyapongsa J et al. | β | 2012 | β |
| Inherited variation at chromosome 12p13.33, including RAD52, influences the risk of squamous cell lung carcinoma. | Shi J et al. | β | 2012 | β |
| Knowledge integration at the center of genomic medicine. | Khoury MJ et al. | β | 2012 | β |
| MK4MDD: a multi-level knowledge base and analysis platform for major depressive disorder. | Guo L et al. | β | 2012 | β |
| Network-based SNP meta-analysis identifies joint and disjoint genetic features across common human diseases. | Arnold M et al. | β | 2012 | β |
| Network graph analysis of gene-gene interactions in genome-wide association study data. | Lee S et al. | β | 2012 | β |
| Shared ancestral susceptibility to colorectal cancer and other nutrition related diseases. | Huhn S et al. | β | 2012 | β |
| The functional MDM2 T309G genetic variant but not P53 Arg72Pro polymorphism is associated with risk of sarcomas: a meta-analysis. | Cai X et al. | β | 2012 | β |
| The genetic epidemiology of idiopathic scoliosis. | Gorman KF et al. | β | 2012 | β |
| Toward modernizing the systematic review pipeline in genetics: efficient updating via data mining. | Wallace BC et al. | β | 2012 | β |
| Trends in population-based studies of human genetics in infectious diseases. | Rowell JL et al. | β | 2012 | β |
| A kinesin-1 binding motif in vaccinia virus that is widespread throughout the human genome. | Dodding MP et al. | β | 2011 | β |
| A meta-analysis of Th2 pathway genetic variants and risk for allergic rhinitis. | Bunyavanich S et al. | β | 2011 | β |
| Assessing and managing risk when sharing aggregate genetic variant data. | Craig DW et al. | β | 2011 | β |
| Cancer GAMAdb: database of cancer genetic associations from meta-analyses and genome-wide association studies. | Schully SD et al. | β | 2011 | β |
| Cardiovascular diseases and genome-wide association studies. | Ndiaye NC et al. | β | 2011 | β |
| Common SNPs in CSF2RB are associated with major depression and schizophrenia in the Chinese Han population. | Chen P et al. | β | 2011 | β |
| Comparing genotyping algorithms for Illumina's Infinium whole-genome SNP BeadChips. | Ritchie ME et al. | β | 2011 | β |
| Comprehensive field synopsis and systematic meta-analyses of genetic association studies in cutaneous melanoma. | Chatzinasiou F et al. | β | 2011 | β |
| Design and coverage of high throughput genotyping arrays optimized for individuals of East Asian, African American, and Latino race/ethnicity using imputation and a novel hybrid SNP selection algorithm. | Hoffmann TJ et al. | β | 2011 | β |
| Evaluation of the global association between cholesterol-associated polymorphisms and Alzheimer's disease suggests a role for rs3846662 and HMGCR splicing in disease risk. | Simmons CR et al. | β | 2011 | β |
| FDA workshop on emerging infectious diseases: evaluating emerging infectious diseases (EIDs) for transfusion safety. | Atreya C et al. | β | 2011 | β |
| Genetic epidemiology with a capital E, ten years after. | Khoury MJ et al. | β | 2011 | β |
| Genetics of complex respiratory diseases: implications for pathophysiology and pharmacology studies. | Obeidat M et al. | β | 2011 | β |
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| The factor XII -4C>T variant and risk of common thrombotic disorders: A HuGE review and meta-analysis of evidence from observational studies. | Johnson CY et al. | β | 2011 | β |
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| Replication of past candidate loci for common diseases and phenotypes in 100 genome-wide association studies. | Siontis KC et al. | β | 2010 | β |
| Saliva-derived DNA performs well in large-scale, high-density single-nucleotide polymorphism microarray studies. | Bahlo M et al. | β | 2010 | β |
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| Invited commentary: genes, environment, and hybrid vigor. | Gwinn M et al. | β | 2009 | β |
| Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand. | Evangelou E et al. | β | 2009 | β |
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| The need for genetic variant naming standards in published abstracts of human genetic association studies. | Yu W et al. | β | 2009 | β |
| The Scientific Foundation for personal genomics: recommendations from a National Institutes of Health-Centers for Disease Control and Prevention multidisciplinary workshop. | Khoury MJ et al. | β | 2009 | β |
| The UCSC Genome Browser Database: update 2009. | Kuhn RM et al. | β | 2009 | β |
| The Val/Met functional polymorphism in COMT confers susceptibility to bipolar disorder: evidence from an association study and a meta-analysis. | Zhang Z et al. | β | 2009 | β |
| A quality assessment of genetic association studies supporting susceptibility and outcome in acute lung injury. | Flores C et al. | β | 2008 | β |
| Contemporary epidemiology of renal cell cancer. | Chow WH et al. | β | 2008 | β |
| GAPscreener: an automatic tool for screening human genetic association literature in PubMed using the support vector machine technique. | Yu W et al. | β | 2008 | β |
| Gene Prospector: an evidence gateway for evaluating potential susceptibility genes and interacting risk factors for human diseases. | Yu W et al. | β | 2008 | β |
| HuGE Watch: tracking trends and patterns of published studies of genetic association and human genome epidemiology in near-real time. | Yu W et al. | β | 2008 | β |
| Public health genomics approach to type 2 diabetes. | Khoury MJ et al. | β | 2008 | β |
| The continued need to synthesize the results of genetic associations across multiple studies. | Yesupriya A et al. | β | 2008 | β |
| Tilting at quixotic trait loci (QTL): an evolutionary perspective on genetic causation. | Weiss KM | β | 2008 | β |