Preresponse cues reduce the impairing effects of alcohol on the execution and suppression of responses.
- Authors
- Marczinski, Cecile A; Fillmore, Mark T
- Year
- 2003
- Journal
- Experimental and clinical psychopharmacology
- PMID
- 12622349
- DOI
- 10.1037//1064-1297.11.1.110
The present study examined the effects of alcohol on the ability to execute and inhibit behavior in a context in which preliminary information signaled the likelihood that a response should be executed or suppressed. Social drinkers (N = 12) performed a cued go/no-go task that required quick responses to go targets and suppression of responses to no-go targets. Performance was tested under 3 doses of alcohol: 0.65 g/kg, 0.45 g/kg, and 0.0 g/kg (placebo). Alcohol had no effect on inhibition and execution when cues correctly signaled these actions. By contrast, alcohol impaired inhibition and execution in a dose-dependent manner when cues incorrectly signaled actions. These findings are consistent with a resource limitation account of alcohol impairment.
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