Extinction circuits for fear and addiction overlap in prefrontal cortex.
paper
Cited
Public
Unavailable
- Authors
- Peters, Jamie; Kalivas, Peter W; Quirk, Gregory J
- Year
- 2009
- Journal
- Learning & memory (Cold Spring Harbor, N.Y.)
- PMID
- 19380710
- DOI
- 10.1101/lm.1041309
- PMCID
- PMC4527308
Extinction is a form of inhibitory learning that suppresses a previously conditioned response. Both fear and drug seeking are conditioned responses that can lead to maladaptive behavior when expressed inappropriately, manifesting as anxiety disorders and addiction, respectively. Recent evidence indicates that the medial prefrontal cortex (mPFC) is critical for the extinction of both fear and drug-seeking behaviors. Moreover, a dorsal-ventral distinction is apparent within the mPFC, such that the prelimbic (PL-mPFC) cortex drives the expression of fear and drug seeking, whereas the infralimbic (IL-mPFC) cortex suppresses these behaviors after extinction. For conditioned fear, the dorsal-ventral dichotomy is accomplished via divergent projections to different subregions of the amygdala, whereas for drug seeking, it is accomplished via divergent projections to the subregions of the nucleus accumbens. Given that the mPFC represents a common node in the extinction circuit for these behaviors, treatments that target this region may help alleviate symptoms of both anxiety and addictive disorders by enhancing extinction memory.
No figures extracted from this document.
No chunks β full text not yet ingested.
No entities extracted from this document yet.
No uploaded files.
Not in any collection.
No citations found.
In this knowledge base
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| A prefrontal cortex-nucleus accumbens circuit attenuates cocaine-conditioned place preference memories. | Wu X et al. | β | 2026 | β |
| Attenuating trauma- and cocaine-related intrusions by blocking memory reconsolidation with minocycline: protocol for a transdiagnostic randomized controlled trial. | Dietiker L et al. | β | 2026 | β |
| Backward conditioning reveals flexibility in infralimbic cortex inhibitory memories. | Lingawi NW et al. | β | 2026 | β |
| Functional interaction between orexin/CRF and orexin/dynorphin transmission in the infralimbic cortex modulates the stress-induced reinstatement of alcohol-seeking behavior in male and female Wistar rats. | Flores-Ramirez FJ et al. | β | 2026 | β |
| Histone Deacetylase 5 in Prelimbic Prefrontal Cortex Limits Context-Associated Cocaine Seeking. | Barry SM et al. | β | 2026 | β |
| Interoceptive Exposure Impacts Food-Cue Extinction in Adolescents With Low-Weight Eating Disorders: A Functional Magnetic Resonance Imaging Study. | Schulz KP et al. | β | 2026 | β |
| Medial prefrontal Cortex, dopamine and glutamate modulation in regulating Reward-Seeking and frustration responses. | de Oliveira Lima CA et al. | β | 2026 | β |
| Activation of infralimbic cortex neurons projecting to the nucleus accumbens shell suppresses discriminative stimulus-triggered relapse to cocaine seeking in rats. | Algallal HE et al. | β | 2025 | β |
| Adolescent vulnerability to methamphetamine: Dose-related escalation of self-administration and cue extinction deficits. | Luikinga SJ et al. | β | 2025 | β |
| Associations of CO<sub>2</sub> reactivity and orexin activity with extinction memory to fear and reward cues: results from a large sample of male rats across multiple studies. | Raskin M et al. | β | 2025 | β |
| Biomolecular correlates of incubated sucrose-seeking within ventromedial prefrontal cortex are sex- and subregion-selective. | Cano FJ et al. | β | 2025 | β |
| Combined stress and alcohol exposure: Synergistic effects on alcohol-seeking behaviors and neuroinflammation. | Wills LJ et al. | β | 2025 | β |
| Dopamine D<sub>3</sub> receptor blockade accelerates the extinction of opioid withdrawal-induced drug-seeking behaviours and alters microglia in dopaminoceptive nuclei. | Franco-GarcΓa A et al. | β | 2025 | β |
| Extinction of Heroin Seeking Does Not Require the Infralimbic Cortex or Its Projections to the Nucleus Accumbens Shell or Amygdala. | McGregor MS et al. | β | 2025 | β |
| Impaired Cognitive Flexibility With Preserved Learning in an Amyloid Precursor Protein Knock-In Mouse Model of Amyloidopathy. | Dumont JR et al. | β | 2025 | β |
| Neuronal ensembles formed rapidly in the prelimbic cortex mediate initial and maintained cocaine-seeking behavior in male and female rats. | Sortman BW et al. | β | 2025 | β |
| Pathway-specific regulation of amphetamine-induced conditioned place preference by chemogenetic modulation of basolateral amygdala projections to prelimbic cortex and nucleus accumbens subregions. | Han J et al. | β | 2025 | β |
| Prefrontal and Subcortical c-Fos Mapping of Reward Responses across Competitive and Social Contexts. | De Paula Cunha Almeida C et al. | β | 2025 | β |
| Progesterone and allopregnanolone facilitate excitatory synaptic transmission in the infralimbic cortex via activation of membrane progesterone receptors. | Rahaei N et al. | β | 2025 | β |
| Targeting VMPFC-amygdala circuit with TMS in substance use disorder: A mechanistic framework. | Soleimani G et al. | β | 2025 | β |
| Tracking conditioned fear in pair-housed mice using deep learning and real-time cue delivery. | Smith HC et al. | β | 2025 | β |
| Transcriptional characterization of cocaine withdrawal versus extinction within nucleus accumbens in male rats. | MartΓnez-Rivera FJ et al. | β | 2025 | β |
| Vagus nerve stimulation modulates cocaine seeking induced synaptic plasticity in reward related brain circuits. | Arezoomandan R et al. | β | 2025 | β |
| Bad habits-good goals? Meta-analysis and translation of the habit construct to alcoholism. | Giannone F et al. | β | 2024 | β |
| Chronic ethanol exposure produces long-lasting, subregion-specific physiological adaptations in RMTg-projecting mPFC neurons. | Przybysz KR et al. | β | 2024 | β |
| Dissociable dorsal medial prefrontal cortex ensembles are necessary for cocaine seeking and fear conditioning in mice. | Liu S et al. | β | 2024 | β |
| Effects of MC-100093 on Ethanol Drinking and the Expression of Astrocytic Glutamate Transporters in the Mesocorticolimbic Brain Regions of Male and Female Alcohol-Preferring Rats. | Alotaibi A et al. | β | 2024 | β |
| Environmental Enrichment during Abstinence Reduces Oxycodone Seeking and c-Fos Expression in a Subpopulation of Medial Prefrontal Cortex Neurons. | Glaeser B et al. | β | 2024 | β |
| Large-scale coupling of prefrontal activity patterns as a mechanism for cognitive control in health and disease: evidence from rodent models. | NegrΓ³n-Oyarzo I et al. | β | 2024 | β |
| Molecular mechanisms underlying sex and treatment-dependent differences in an animal model of cue-exposure therapy for cocaine relapse prevention. | Peterson L et al. | β | 2024 | β |
| Neuroanatomical Substrates of Circuit-Specific Cholinergic Modulation across the Primate Anterior Cingulate Cortex. | Tsolias A et al. | β | 2024 | β |
| Novel psychoplastogen DM506 reduces cue-induced heroin-seeking and inhibits tonic GABA currents in the Prelimbic Cortex. | Looschen K et al. | β | 2024 | β |
| Perineuronal Nets in the CNS: Architects of Memory and Potential Therapeutic Target in Neuropsychiatric Disorders. | Li X et al. | β | 2024 | β |
| Prefrontal cortex neurons encode ambient light intensity differentially across regions and layers. | Zangen E et al. | β | 2024 | β |
| Sex differences in neuronal activation in the cortex and midbrain during quinine-adulterated alcohol intake. | Arnold ME et al. | β | 2024 | β |
| The mouse dorsal peduncular cortex encodes fear memory. | Campos-Cardoso R et al. | β | 2024 | β |
| Vagus Nerve Stimulation (VNS) Modulates Synaptic Plasticity in the Infralimbic Cortex via Trk-B Receptor Activation to Reduce Drug-Seeking in Male Rats. | Driskill CM et al. | β | 2024 | β |
| Abstinence from Escalation of Cocaine Intake Changes the microRNA Landscape in the Cortico-Accumbal Pathway. | Kumaresan V et al. | β | 2023 | β |
| Altered neuronal activity in the ventromedial prefrontal cortex drives nicotine intake escalation. | Abarkan M et al. | β | 2023 | β |
| A new circuit underlying the renewal of appetitive Pavlovian responses: Commentary on Brown and Chaudhri (2022). | Valyear MD et al. | β | 2023 | β |
| Chronic restraint stress increases sensitivity to punishment during cocaine self-administration via a dopamine D<sub>1</sub>-like receptor-mediated mechanism in prelimbic medial prefrontal cortex. | Ball KT et al. | β | 2023 | β |
| CO<sub>2</sub> reactivity is associated with individual differences in appetitive extinction memory. | Raskin M et al. | β | 2023 | β |
| Estradiol and progesterone in female reward-learning, addiction, and therapeutic interventions. | Hilz EN et al. | β | 2023 | β |
| Frontopolar multifocal transcranial direct current stimulation reduces conditioned fear reactivity during extinction training: A pilot randomized controlled trial. | Adams TG et al. | β | 2023 | β |
| HCN-Channel-Dependent Hyperexcitability of the Layer V Pyramidal Neurons in IL-mPFC Contributes to Fentanyl-Induced Hyperalgesia in Male Rats. | Wang X et al. | β | 2023 | β |
| Histochemical mapping of the duration of action of photobiomodulation on cytochrome c oxidase in the rat brain. | Wade ZS et al. | β | 2023 | β |
| Infralimbic Projections to the Nucleus Accumbens Shell and Amygdala Regulate the Encoding of Cocaine Extinction Learning. | Nett KE et al. | β | 2023 | β |
| Inhibitory and excitatory alcohol-seeking cues distinct roles in behavior, neurochemistry, and mesolimbic pathway in alcohol preferring (P) rats. | Hauser SR et al. | β | 2023 | β |
| Involvement of cortical input to the rostromedial tegmental nucleus in aversion to foot shock. | Glover EJ et al. | β | 2023 | β |
| Learning processes in relapse to alcohol use: lessons from animal models. | Valyear MD et al. | β | 2023 | β |
| Neural correlates of recall and extinction in a rat model of appetitive Pavlovian conditioning. | Brown A et al. | β | 2023 | β |
| Optogenetic stimulation of infralimbic cortex projections to the paraventricular thalamus attenuates context-induced renewal. | Brown A et al. | β | 2023 | β |
| Prelimbic and infralimbic medial prefrontal cortex neuron activity signals cocaine seeking variables across multiple timescales. | Moorman DE et al. | β | 2023 | β |
| Reduced Expression of the Htr2a, Grin1, and Bdnf Genes and Cognitive Inflexibility in a Model of High Compulsive Rats. | Prados-Pardo Γ et al. | β | 2023 | β |
| Role of Piriform Cortex and Its Afferent Projections in Relapse to Fentanyl Seeking after Food Choice-Induced Voluntary Abstinence. | Claypool SM et al. | β | 2023 | β |
| Selective ablation of VIP interneurons in the rodent prefrontal cortex results in increased impulsivity. | Hatter JA et al. | β | 2023 | β |
| Sex differences in mouse infralimbic cortex projections to the nucleus accumbens shell. | Johnson CS et al. | β | 2023 | β |
| Sex differences in neuronal activation during aversion-resistant alcohol consumption. | Arnold ME et al. | β | 2023 | β |
| Subunit-selective PI3-kinase control of action strategies in the medial prefrontal cortex. | Davies RA et al. | β | 2023 | β |
| The Effects of the Inhalant Toluene on Cognitive Function and Behavioral Flexibility: A Review of Recent Findings. | Woodward JJ et al. | β | 2023 | β |
| The interaction of membrane estradiol receptors and metabotropic glutamate receptors in adaptive and maladaptive estradiol-mediated motivated behaviors in females. | Johnson CS et al. | β | 2023 | β |
| Top-down circuitry from the anterior insular cortex to VTA dopamine neurons modulates reward-related memory. | HernΓ‘ndez-Ortiz E et al. | β | 2023 | β |
| Transcranial Magnetic Stimulation as a Tool to Promote Smoking Cessation and Decrease Drug and Alcohol Use. | Harmelech T et al. | β | 2023 | β |
| Use of experimental medicine approaches for the development of novel psychiatric treatments based on orexin receptor modulation. | Beckenstrom AC et al. | β | 2023 | β |
| Adolescence alcohol exposure impairs fear extinction and alters medial prefrontal cortex plasticity. | Lawson K et al. | β | 2022 | β |
| Age-related differences in the effect of chronic alcohol on cognition and the brain: a systematic review. | Kuhns L et al. | β | 2022 | β |
| An opioid-gated thalamoaccumbal circuit for the suppression of reward seeking in mice. | Vollmer KM et al. | β | 2022 | β |
| Brain Network Allostasis after Chronic Alcohol Drinking Is Characterized by Functional Dedifferentiation and Narrowing. | PΓ©rez-RamΓrez Γ et al. | β | 2022 | β |
| Brief Environmental Enrichment exposure enhances contextual-induced sucrose-seeking with and without memory reactivation in rats. | Pintori N et al. | β | 2022 | β |
| Comparison of prefrontal cortex sucrose seeking ensembles engaged in multiple seeking sessions: Context is key. | Jessen K et al. | β | 2022 | β |
| Compensatory Role of Insulin in the Extinction but Not Reinstatement of Morphine-Induced Conditioned Place Preference in the Streptozotocin-Induced Diabetic Rats. | Chizari A et al. | β | 2022 | β |
| Cortico-Striatal Control over Adaptive Goal-Directed Responding Elicited by Cues Signaling Sucrose Reward or Punishment. | Hamel L et al. | β | 2022 | β |
| Corticostriatal Suppression of Appetitive Pavlovian Conditioned Responding. | Villaruel FR et al. | β | 2022 | β |
| Deep Brain Stimulation for Addictive Disorders-Where Are We Now? | Yuen J et al. | β | 2022 | β |
| Dynamic ΞΈ Frequency Coordination within and between the Prefrontal Cortex-Hippocampus Circuit during Learning of a Spatial Avoidance Task. | Dickson CR et al. | β | 2022 | β |
| Efferent and afferent connections of supratrigeminal neurons conveying orofacial muscle proprioception in rats. | Yoshida A et al. | β | 2022 | β |
| Hippocampal and amygdalar increased BDNF expression in the extinction of opioid-induced place preference. | Lloret-Torres ME et al. | β | 2022 | β |
| Impairments in Fear Extinction Memory and Basolateral Amygdala Plasticity in the TgF344-AD Rat Model of Alzheimer's Disease Are Distinct from Nonpathological Aging. | Hernandez CM et al. | β | 2022 | β |
| Plexin-A1 expression in the inhibitory neurons of infralimbic cortex regulates the specificity of fear memory in male mice. | Cheng X et al. | β | 2022 | β |
| Prelimbic Ensembles Mediate Cocaine Seeking After Behavioral Acquisition and Once Rats Are Well-Trained. | Sortman BW et al. | β | 2022 | β |
| Profiling prefrontal cortex protein expression in rats exhibiting an incubation of cocaine craving following short-access self-administration procedures. | Huerta Sanchez LL et al. | β | 2022 | β |
| Repetitive Transcranial Magnetic Stimulation inΒ Alcohol Dependence: A Randomized, Double-Blind, Sham-Controlled Proof-of-Concept Trial Targeting the Medial Prefrontal andΒ Anterior Cingulate Cortices. | Harel M et al. | β | 2022 | β |
| Sex differences in the effect of chronic delivery of the buprenorphine analogue BU08028 on heroin relapse and choice in a rat model of opioid maintenance. | Bossert JM et al. | β | 2022 | β |
| Sex differences in the medial prefrontal cortical glutamate system. | Knouse MC et al. | β | 2022 | β |
| Structural, functional, and behavioral significance of sex and gonadal hormones in the basolateral amygdala: A review of preclinical literature. | Price ME et al. | β | 2022 | β |
| The rodent medial prefrontal cortex and associated circuits in orchestrating adaptive behavior under variable demands. | Howland JG et al. | β | 2022 | β |
| Transcranial direct current stimulation targeting the medial prefrontal cortex modulates functional connectivity and enhances safety learning in obsessive-compulsive disorder: Results from two pilot studies. | Adams TG et al. | β | 2022 | β |
| Traumatic Stress-Induced Vulnerability to Addiction: Critical Role of the Dynorphin/Kappa Opioid Receptor System. | Leconte C et al. | β | 2022 | β |
| When the front fails, the rear wins. Cerebellar correlates of prefrontal dysfunction in cocaine-induced memory in male rats. | Guarque-Chabrera J et al. | β | 2022 | β |
| Where Actions Meet Outcomes: Medial Prefrontal Cortex, Central Thalamus, and the Basal Ganglia. | Mair RG et al. | β | 2022 | β |
| A common limiter circuit for opioid choice and relapse identified in a rodent addiction model. | Heinsbroek JA et al. | β | 2021 | β |
| Acute vagus nerve stimulation enhances reversal learning in rats. | Altidor LK et al. | β | 2021 | β |
| A sex-dependent role for the prelimbic cortex in impulsive action both before and following early cocaine abstinence. | Moschak TM et al. | β | 2021 | β |
| A Synaptic Framework for the Persistence of Memory Engrams. | Rao-Ruiz P et al. | β | 2021 | β |
| Aversive stimuli bias corticothalamic responses to motivationally significant cues. | Lucantonio F et al. | β | 2021 | β |
| BDNF Protein and BDNF mRNA Expression of the Medial Prefrontal Cortex, Amygdala, and Hippocampus during Situational Reminder in the PTSD Animal Model. | Chang SH et al. | β | 2021 | β |
| BEHAVIORAL AND NEUROBIOLOGICAL MECHANISMS OF PAVLOVIAN AND INSTRUMENTAL EXTINCTION LEARNING. | Bouton ME et al. | β | 2021 | β |
| Berberine Facilitates Extinction and Prevents the Return of Fear. | Huang S et al. | β | 2021 | β |
| Brain reward circuitry: The overlapping neurobiology of trauma and substance use disorders. | Michaels TI et al. | β | 2021 | β |
| Circuit selectivity in drug versus natural reward seeking behaviors. | Nall RW et al. | β | 2021 | β |
| Deep TMS H7 Coil: Features, Applications & Future. | Harmelech T et al. | β | 2021 | β |
| Dissociable control of ΞΌ-opioid-driven hyperphagia vs. food impulsivity across subregions of medial prefrontal, orbitofrontal, and insular cortex. | Giacomini JL et al. | β | 2021 | β |
| Dissociable roles of the nucleus accumbens core and shell subregions in the expression and extinction of conditioned fear. | Dutta S et al. | β | 2021 | β |
| Downregulation of Synaptotagmin 1 in the Prelimbic Cortex Drives Alcohol-Associated Behaviors in Rats. | Barbier E et al. | β | 2021 | β |
| Early Life Stress and Risks for Opioid Misuse: Review of Data Supporting Neurobiological Underpinnings. | Oswald LM et al. | β | 2021 | β |
| Engineering Safer Psychedelics for Treating Addiction. | Peters J et al. | β | 2021 | β |
| Examination of neuroinflammatory cytokine interleukin-1 beta expression in the medial prefrontal cortex, amygdala, and hippocampus for the paradoxical effects of reward and aversion induced by morphine. | Wang YC et al. | β | 2021 | β |
| Exposure to Running Wheels Prevents Ethanol Rewarding Effects: The Role of CREB and Deacetylases SIRT-1 and SIRT-2 in the Nucleus Accumbens and Prefrontal Cortex. | ContΓ³ MB et al. | β | 2021 | β |
| Extinction and drug-induced reinstatement of cocaine seeking following self-administration or conditioned place preference in adolescent and adult rats. | Guerin AA et al. | β | 2021 | β |
| Extinction blunts paraventricular thalamic contributions to heroin relapse. | Giannotti G et al. | β | 2021 | β |
| Fear conditioning and extinction in alcohol dependence: Evidence for abnormal amygdala reactivity. | Muench C et al. | β | 2021 | β |
| Fos-expressing neuronal ensemble in rat ventromedial prefrontal cortex encodes cocaine seeking but not food seeking in rats. | Kane L et al. | β | 2021 | β |
| Granulocyte-Colony Stimulating Factor Reduces Cocaine-Seeking and Downregulates Glutamatergic Synaptic Proteins in Medial Prefrontal Cortex. | Hofford RS et al. | β | 2021 | β |
| Impact of Acute and Persistent Excitation of Prelimbic Pyramidal Neurons on Motor Activity and Trace Fear Learning. | Rose TR et al. | β | 2021 | β |
| Inactivation of the infralimbic cortex decreases discriminative stimulus-controlled relapse to cocaine seeking in rats. | Madangopal R et al. | β | 2021 | β |
| Infralimbic cortex functioning across motivated behaviors: Can the differences be reconciled? | Nett KE et al. | β | 2021 | β |
| Integration of value and action in medial prefrontal neural systems. | Kaminska B et al. | β | 2021 | β |
| Medial prefrontal cortical control of reward- and aversion-based behavioral output: Bottom-up modulation. | Pastor V et al. | β | 2021 | β |
| Methamphetamine and Modulation Functionality of the Prelimbic Cortex for Developing a Possible Treatment of Alzheimer's Disease in an Animal Model. | Shyu BC et al. | β | 2021 | β |
| Neuroimaging reveals functionally distinct neuronal networks associated with high-level alcohol consumption in two genetic rat models. | PallarΓ©s V et al. | β | 2021 | β |
| Opioid-induced structural and functional plasticity of medium-spiny neurons in the nucleus accumbens. | Thompson BL et al. | β | 2021 | β |
| Preclinical evidence to support repurposing everolimus for craving reduction during protracted drug withdrawal. | Chiu AS et al. | β | 2021 | β |
| Prefrontal cortex nicotinic receptor inhibition by methyllycaconitine impaired cocaine-associated memory acquisition and retrieval. | Pastor V et al. | β | 2021 | β |
| Prefrontal inhibition drives formation and dynamic expression of probabilistic Pavlovian fear conditioning. | Yan R et al. | β | 2021 | β |
| Prefrontal-Limbic Connectivity in Depressive Behavior: Sex as a Critical Factor. | Moschak TM | β | 2021 | β |
| Prelimbic cortical projections to rostromedial tegmental nucleus play a suppressive role in cue-induced reinstatement of cocaine seeking. | Cruz AM et al. | β | 2021 | β |
| Psychedelics and Other Psychoplastogens for Treating Mental Illness. | Vargas MV et al. | β | 2021 | β |
| The learning of prospective and retrospective cognitive maps within neural circuits. | K Namboodiri VM et al. | β | 2021 | β |
| The mouse prefrontal cortex: Unity in diversity. | Le Merre P et al. | β | 2021 | β |
| The neural, behavioral, and epidemiological underpinnings of comorbid alcohol use disorder and post-traumatic stress disorder. | Carlson HN et al. | β | 2021 | β |
| The Neurotransmitter Receptor Architecture of the Mouse Olfactory System. | Lothmann K et al. | β | 2021 | β |
| The role of the serotonin transporter in prefrontal cortex glutamatergic signaling following short- and long-access cocaine self-administration. | Caffino L et al. | β | 2021 | β |
| Valence processing in the PFC: Reconciling circuit-level and systems-level views. | Coley AA et al. | β | 2021 | β |
| A Computational Model Integrating Multiple Phenomena on Cued Fear Conditioning, Extinction, and Reinstatement. | Mattera A et al. | β | 2020 | β |
| A Critical Role of Basolateral Amygdala-to-Nucleus Accumbens Projection inΒ Sleep Regulation of Reward Seeking. | Wang Y et al. | β | 2020 | β |
| Acute ovarian hormone treatment in freely cycling female rats regulates distinct aspects of heroin seeking. | Vazquez M et al. | β | 2020 | β |
| Angelman Syndrome: From Mouse Models to Therapy. | Rotaru DC et al. | β | 2020 | β |
| Basolateral Amygdala but Not Medial Prefrontal Cortex Contributes to Chronic Fluoxetine Treatments for PTSD Symptoms in Mice. | Yu YH et al. | β | 2020 | β |
| Chronic Ethanol Differentially Modulates Glutamate Release from Dorsal and Ventral Prefrontal Cortical Inputs onto Rat Basolateral Amygdala Principal Neurons. | McGinnis MM et al. | β | 2020 | β |
| Cue-elicited functional connectivity of the periaqueductal gray and tonic cocaine craving. | Zhang S et al. | β | 2020 | β |
| Different Multidimensional Representations across the Amygdalo-Prefrontal Network during an Approach-Avoidance Task. | Kyriazi P et al. | β | 2020 | β |
| Dopamine Axon Targeting in the Nucleus Accumbens in Adolescence Requires Netrin-1. | Cuesta S et al. | β | 2020 | β |
| Effects of TRPV1 Activation by Capsaicin and Endogenous N-Arachidonoyl Taurine on Synaptic Transmission in the Prefrontal Cortex. | Zhang M et al. | β | 2020 | β |
| Exposure therapy vs lifestyle intervention to reduce food cue reactivity and binge eating in obesity: A pilot study. | Schyns G et al. | β | 2020 | β |
| Extinction of cue-evoked food-seeking recruits a GABAergic interneuron ensemble in the dorsal medial prefrontal cortex of mice. | Brebner LS et al. | β | 2020 | β |
| From Isolated Emotional Memories to Their Competition During Conflict. | Bravo-Rivera C et al. | β | 2020 | β |
| Improving translation of animal models of addiction and relapse by reverse translation. | Venniro M et al. | β | 2020 | β |
| Interactions between prelimbic cortex and basolateral amygdala contribute to morphine-induced conditioned taste aversion in conditioning and extinction. | Huang ACW et al. | β | 2020 | β |
| Lasting reduction of nicotine-seeking behavior by chronic N-acetylcysteine during experimental cue-exposure therapy. | Moro F et al. | β | 2020 | β |
| Mechanisms of Shared Vulnerability to Post-traumatic Stress Disorder and Substance Use Disorders. | MarΓa-RΓos CE et al. | β | 2020 | β |
| Modulation of intrinsic excitability as a function of learning within the fear conditioning circuit. | Yousuf H et al. | β | 2020 | β |
| Modulation of Poly ADP Ribose Polymerase (PARP) Levels and Activity by Alcohol Binge-Like Drinking in Male Mice. | Vallerini GP et al. | β | 2020 | β |
| Neural circuits linking sleep and addiction: Animal models to understand why select individuals are more vulnerable to substance use disorders after sleep deprivation. | Ahrens AM et al. | β | 2020 | β |
| nNOS-expressing neurons in the vmPFC transform pPVT-derived chronic pain signals into anxiety behaviors. | Liang HY et al. | β | 2020 | β |
| Opposing Regulation of Cocaine Seeking by Glutamate and GABA Neurons in the Ventral Pallidum. | Heinsbroek JA et al. | β | 2020 | β |
| Pharmacological Inactivation of Medial Prefrontal Cortex Does Not Support Dichotomous "Go/Stop" Roles for Dorsal and Ventral Subdivisions in Natural Reward Seeking in Rats. | Carney RSE | β | 2020 | β |
| Prefrontal cortical and nucleus accumbens contributions to discriminative conditioned suppression of reward-seeking. | Piantadosi PT et al. | β | 2020 | β |
| Prefrontal Regulation of Punished Ethanol Self-administration. | Halladay LR et al. | β | 2020 | β |
| Role of mPFC and nucleus accumbens circuitry in modulation of a nicotine plus alcohol compound drug state. | Randall PA et al. | β | 2020 | β |
| The anterior insular cortex in the rat exerts an inhibitory influence over the loss of control of heroin intake and subsequent propensity to relapse. | Joshi DD et al. | β | 2020 | β |
| The infralimbic cortex and mGlu5 mediate the effects of chronic intermittent ethanol exposure on fear learning and memory. | Smiley CE et al. | β | 2020 | β |
| The reinforcing effects of ethanol within the prelimbic cortex and ethanol drinking: Involvement of local dopamine D<sub>2</sub> receptor-mediated neurotransmission. | Engleman EA et al. | β | 2020 | β |
| The role of catecholamines in modulating responses to stress: Sex-specific patterns, implications, and therapeutic potential for post-traumatic stress disorder and opiate withdrawal. | Ross JA et al. | β | 2020 | β |
| Transgenic Analyses of Homer2 Function Within Nucleus Accumbens Subregions in the Regulation of Methamphetamine Reward and Reinforcement in Mice. | Brown CN et al. | β | 2020 | β |
| Vulnerability to diet-induced obesity is associated with greater food priming-induced reinstatement of palatable food seeking. | Bodnar H et al. | β | 2020 | β |
| Who worries about specific phobias? - A population-based study of risk factors. | Coelho CM et al. | β | 2020 | β |
| Alternation in dopamine D<sub>2</sub>-like and metabotropic glutamate type 5 receptor density caused by differing housing conditions during abstinence from cocaine self-administration in rats. | Frankowska M et al. | β | 2019 | β |
| Amphetamine-induced Conditioned Place Preference and Changes in mGlu1/5 Receptor Expression and Signaling in the Rat Medial Prefrontal Cortex. | Mao LM et al. | β | 2019 | β |
| A natural antisense to brain-derived neurotrophic factor impairs extinction of drug seeking | Youngson NA et al. | β | 2019 | β |
| Anti-relapse neurons in the infralimbic cortex of rats drive relapse-suppression by drug omission cues. | Laque A et al. | β | 2019 | β |
| Appetitive to aversive counter-conditioning as intervention to reduce reinstatement of reward-seeking behavior: the role of the serotonin transporter. | Karel P et al. | β | 2019 | β |
| Attenuation of cocaine seeking in rats via enhancement of infralimbic cortical activity using stable step-function opsins. | MΓΌller Ewald VA et al. | β | 2019 | β |
| Brain and Cognition for Addiction Medicine: From Prevention to Recovery Neural Substrates for Treatment of Psychostimulant-Induced Cognitive Deficits. | D'Souza MS | β | 2019 | β |
| Chemogenetic stimulation of the infralimbic cortex reverses alcohol-induced fear memory overgeneralization. | Scarlata MJ et al. | β | 2019 | β |
| Cocaine treatment before pregnancy differentially affects the anxiety and brain glucose metabolism of lactating rats if performed during adulthood or adolescence. | Delgado H et al. | β | 2019 | β |
| Common neurocircuitry mediating drug and fear relapse in preclinical models. | Goode TD et al. | β | 2019 | β |
| Conserved features of anterior cingulate networks support observational learning across species. | Burgos-Robles A et al. | β | 2019 | β |
| Cue Exposure Therapy for Alcohol Use Disorders: What Can Be Learned from Exposure Therapy for Anxiety Disorders? | Byrne SP et al. | β | 2019 | β |
| Development of working memory in the male adolescent rat. | Kirschmann EK et al. | β | 2019 | β |
| Differential Effects of Dorsal and Ventral Medial Prefrontal Cortex Inactivation during Natural Reward Seeking, Extinction, and Cue-Induced Reinstatement. | Caballero JP et al. | β | 2019 | β |
| Diminished Fear Extinction in Adolescents Is Associated With an Altered Somatostatin Interneuron-Mediated Inhibition in the Infralimbic Cortex. | Koppensteiner P et al. | β | 2019 | β |
| Dorsomedial prefrontal cortex neurons encode nicotine-cue associations. | Struik RF et al. | β | 2019 | β |
| Efficacy of Invasive and Non-Invasive Brain Modulation Interventions for Addiction. | Luigjes J et al. | β | 2019 | β |
| Extinction training following cocaine or MDMA self-administration produces discrete changes in D<sub>2</sub>-like and mGlu<sub>5</sub> receptor density in the rat brain. | Frankowska M et al. | β | 2019 | β |
| Image-guided cranial irradiation-induced ablation of dentate gyrus neurogenesis impairs extinction of recent morphine reward memories. | Rivera PD et al. | β | 2019 | β |
| Integrative analysis of shared genetic pathogenesis by autism spectrum disorder and obsessive-compulsive disorder. | Liu D et al. | β | 2019 | β |
| Interactions between neural decision-making circuits predict long-term dietary treatment success in obesity. | Weygandt M et al. | β | 2019 | β |
| In vivo electrophysiological recordings of the effects of antidepressant drugs. | Fitzgerald PJ et al. | β | 2019 | β |
| Involvement of neural substrates in reward and aversion to methamphetamine addiction: Testing the reward comparison hypothesis and the paradoxical effect hypothesis of abused drugs. | He ABH et al. | β | 2019 | β |
| Lack of experience-dependent intrinsic plasticity in the adolescent infralimbic medial prefrontal cortex. | Koppensteiner P et al. | β | 2019 | β |
| Modulating Dopamine Signaling and Behavior with Chemogenetics: Concepts, Progress, and Challenges. | Runegaard AH et al. | β | 2019 | β |
| Neural mechanisms of extinguishing drug and pleasant cue associations in human addiction: role of the VMPFC. | Konova AB et al. | β | 2019 | β |
| Neuroplasticity transcript profile of the ventral striatum in the extinction of opioid-induced conditioned place preference. | MartΓnez-Rivera FJ et al. | β | 2019 | β |
| NMDA receptor subunits change in the prefrontal cortex of pure-opioid and multi-drug abusers: a post-mortem study. | Daneshparvar H et al. | β | 2019 | β |
| Nucleus Accumbens Shell Orexin-1 Receptors Are Critical Mediators of Binge Intake in Excessive-Drinking Individuals. | Lei K et al. | β | 2019 | β |
| Opposing roles for amygdala and vmPFC in the return of appetitive conditioned responses in humans. | Ebrahimi C et al. | β | 2019 | β |
| Prefrontal circuit organization for executive control. | Kamigaki T | β | 2019 | β |
| Prefrontal circuits signaling active avoidanceΒ retrieval and extinction. | MartΓnez-Rivera FJ et al. | β | 2019 | β |
| Prelimbic and infralimbic cortical inactivations attenuate contextually driven discriminative responding for reward. | Riaz S et al. | β | 2019 | β |
| Rapid reacquisition of contextual fear following extinction in mice: effects of amount of extinction, acute ethanol withdrawal, and ethanol intoxication. | Williams AR et al. | β | 2019 | β |
| Reduced Glutamate in the Medial Prefrontal Cortex Is Associated With Emotional and Cognitive Dysregulation in People With Chronic Pain. | Naylor B et al. | β | 2019 | β |
| Regulation of HDAC1 and HDAC2 during consolidation and extinction of fear memory. | Siddiqui SA et al. | β | 2019 | β |
| Repeated blast model of mild traumatic brain injury alters oxycodone self-administration and drug seeking. | Nawarawong NN et al. | β | 2019 | β |
| Role of prefrontal cortex in the extinction of drug memories. | Zhang WH et al. | β | 2019 | β |
| Separate vmPFC Ensembles Control Cocaine Self-Administration Versus Extinction in Rats. | Warren BL et al. | β | 2019 | β |
| Severe seizures as a side effect of deep brain stimulation in the dorsal peduncular cortex in a rat model of depression. | Roet M et al. | β | 2019 | β |
| Sign-tracking behavior is difficult to extinguish and resistant to multiple cognitive enhancers. | Fitzpatrick CJ et al. | β | 2019 | β |
| Single-Prolonged Stress Impairs Prefrontal Cortex Control of Amygdala and Striatum in Rats. | Piggott VM et al. | β | 2019 | β |
| Subregion-specific Protective Effects of Fluoxetine and Clozapine on Parvalbumin Expression in Medial Prefrontal Cortex of Chronically Isolated Rats. | TodoroviΔ N et al. | β | 2019 | β |
| The DNA modification N6-methyl-2'-deoxyadenosine (m6dA) drives activity-induced gene expression and is required for fear extinction. | Li X et al. | β | 2019 | β |
| The emerging neuroscience of appetitive and drug cue extinction in humans. | Konova AB et al. | β | 2019 | β |
| The role of stress in drug addiction. An integrative review. | Ruisoto P et al. | β | 2019 | β |
| The Sigma-1 Receptor: When Adaptive Regulation of Cell Electrical Activity Contributes to Stimulant Addiction and Cancer. | Soriani O et al. | β | 2019 | β |
| Trauma-associated anterior cingulate connectivity during reward learning predicts affective and anxiety states in young adults. | Eckstrand KL et al. | β | 2019 | β |
| Vagus nerve stimulation during extinction learning reduces conditioned place preference and context-induced reinstatement ofΒ cocaine seeking. | Childs JE et al. | β | 2019 | β |
| Altering gain of the infralimbic-to-accumbens shell circuit alters economically dissociable decision-making algorithms. | Sweis BM et al. | β | 2018 | β |
| Behavioral and neural mechanisms underlying habitual and compulsive drug seeking. | Smith RJ et al. | β | 2018 | β |
| Behavioral and neurobiological mechanisms of punishment: implications for psychiatric disorders. | Jean-Richard-Dit-Bressel P et al. | β | 2018 | β |
| Beyond simple tests of value: measuring addiction as a heterogeneous disease of computation-specific valuation processes. | Sweis BM et al. | β | 2018 | β |
| bFGF expression is differentially regulated by cocaine seeking versus extinction in learning-related brain regions. | Doncheck EM et al. | β | 2018 | β |
| Cell-Type-Specific Contributions of Medial Prefrontal Neurons to Flexible Behaviors. | Nakayama H et al. | β | 2018 | β |
| Change in emotional self-concept following socio-cognitive training relates to structural plasticity of the prefrontal cortex. | Lumma AL et al. | β | 2018 | β |
| Chasing the addicted engram: identifying functional alterations in Fos-expressing neuronal ensembles that mediate drug-related learned behavior. | Whitaker LR et al. | β | 2018 | β |
| Chemogenetic Excitation of Accumbens-Projecting Infralimbic Cortical Neurons Blocks Toluene-Induced Conditioned Place Preference. | Wayman WN et al. | β | 2018 | β |
| Choice for Drug or Natural Reward Engages Largely Overlapping Neuronal Ensembles in the Infralimbic Prefrontal Cortex. | Pfarr S et al. | β | 2018 | β |
| Chronic restraint stress during withdrawal increases vulnerability to drug priming-induced cocaine seeking via a dopamine D1-like receptor-mediated mechanism. | Ball KT et al. | β | 2018 | β |
| Comparison of the Role of D1- and D2-Like Receptors in the CA1 Region of the Hippocampus in the Reinstatement Induced by a Subthreshold Dose of Morphine and Forced Swim Stress in Extinguished Morphine-CPP in Rats. | Nazari-Serenjeh F et al. | β | 2018 | β |
| Contributions of medial prefrontal cortex to decision making involving risk of punishment. | Orsini CA et al. | β | 2018 | β |
| Crayfish Learning: Addiction and the Ganglionic Brain. | van Staaden MJ et al. | β | 2018 | β |
| Cued fear memory generalization increases over time. | Pollack GA et al. | β | 2018 | β |
| d-Cycloserine enhanced extinction of cocaine-induced conditioned place preference is attenuated in serotonin transporter knockout rats. | Karel P et al. | β | 2018 | β |
| Diminishing fear: Optogenetic approach toward understanding neural circuits of fear control. | Luchkina NV et al. | β | 2018 | β |
| Divergent prefrontal dopaminergic mechanisms mediate drug- and fear-associated cue extinction during adolescence versus adulthood. | Zbukvic IC et al. | β | 2018 | β |
| Effects of Cannabinoid Drugs on Aversive or Rewarding Drug-Associated Memory Extinction and Reconsolidation. | Stern CAJ et al. | β | 2018 | β |
| Effects of Mild Blast Traumatic Brain Injury on Cognitive- and Addiction-Related Behaviors. | Muelbl MJ et al. | β | 2018 | β |
| Emerging role for the medial prefrontal cortex in alcohol-seeking behaviors. | Klenowski PM | β | 2018 | β |
| Enhanced Operant Extinction and Prefrontal Excitability in a Mouse Model of Angelman Syndrome. | Sidorov MS et al. | β | 2018 | β |
| Exposure to the Abused Inhalant Toluene Alters Medial Prefrontal Cortex Physiology. | Wayman WN et al. | β | 2018 | β |
| How expectations influence pain. | Fields HL | β | 2018 | β |
| Infralimbic cortex is required for learning alternatives to prelimbic promoted associations through reciprocal connectivity. | Mukherjee A et al. | β | 2018 | β |
| Interplay of prefrontal cortex and amygdala during extinction of drug seeking. | Oliva V et al. | β | 2018 | β |
| Kinase interest you in treating incubated cocaine-craving? A hypothetical model for treatment intervention during protracted withdrawal from cocaine. | Szumlinski KK et al. | β | 2018 | β |
| Modeling cocaine relapse in rodents: Behavioral considerations and circuit mechanisms. | Farrell MR et al. | β | 2018 | β |
| Morphological and functional evidence of increased excitatory signaling in the prelimbic cortex during ethanol withdrawal. | Varodayan FP et al. | β | 2018 | β |
| Neural Correlates of Compulsive Alcohol Seeking in Heavy Drinkers. | Grodin EN et al. | β | 2018 | β |
| Neural systems mediating the inhibition of cocaine-seeking behaviors. | Muller Ewald VA et al. | β | 2018 | β |
| Phosphorylation of calcium/calmodulin-dependent protein kinase II in the rat dorsal medial prefrontal cortex is associated with alcohol-induced cognitive inflexibility. | Natividad LA et al. | β | 2018 | β |
| Self-efficacy modulates the neural correlates of craving in male smokers and ex-smokers: an fMRI study. | Ono M et al. | β | 2018 | β |
| The Multifaceted Role of the Ventromedial Prefrontal Cortex in Emotion, Decision Making, Social Cognition, and Psychopathology. | Hiser J et al. | β | 2018 | β |
| Thiamine tetrahydrofurfuryl disulfide promotes voluntary activity through dopaminergic activation in the medial prefrontal cortex. | Saiki M et al. | β | 2018 | β |
| Trace Fear Conditioning: Procedure for Assessing Complex Hippocampal Function in Mice. | Sharma V et al. | β | 2018 | β |
| Traumatic Stress Produces Distinct Activations of GABAergic and Glutamatergic Neurons in Amygdala. | Fang Q et al. | β | 2018 | β |
| Ventral pallidal encoding of reward-seeking behavior depends on the underlying associative structure. | Richard JM et al. | β | 2018 | β |
| Viral strategies for targeting cortical circuits that control cocaine-taking and cocaine-seeking in rodents. | Garcia AF et al. | β | 2018 | β |
| Ξ²-Arrestin-biased Ξ²-adrenergic signaling promotes extinction learning of cocaine reward memory. | Huang B et al. | β | 2018 | β |
| Activation of type 4 dopaminergic receptors in the prelimbic area of medial prefrontal cortex is necessary for the expression of innate fear behavior. | Vergara MD et al. | β | 2017 | β |
| Addictive neurons. | Kodirov SA | β | 2017 | β |
| A Decade of Orexin/Hypocretin and Addiction: Where Are We Now? | James MH et al. | β | 2017 | β |
| Age-dependent expression of Nav1.9 channels in medial prefrontal cortex pyramidal neurons in rats. | Gawlak M et al. | β | 2017 | β |
| Aripiprazole Facilitates Extinction of Conditioned Fear in Adolescent Rats. | Ganella DE et al. | β | 2017 | β |
| Cannabidiol regulation of emotion and emotional memory processing: relevance for treating anxiety-related and substance abuse disorders. | Lee JLC et al. | β | 2017 | β |
| Circadian Rhythms and Substance Abuse: Chronobiological Considerations for the Treatment of Addiction. | Webb IC | β | 2017 | β |
| Combining D-cycloserine with appetitive extinction learning modulates amygdala activity during recall. | Ebrahimi C et al. | β | 2017 | β |
| Cortical and amygdalar neuronal ensembles in alcohol seeking, drinking and withdrawal. | George O et al. | β | 2017 | β |
| Deep brain stimulation of the nucleus accumbens core but not shell reduces motivational components of heroin taking and seeking in rats. | Schippers MC et al. | β | 2017 | β |
| Deficits in the extinction of ethanol-seeking behavior following chronic intermittent ethanol exposure are attenuated with positive allosteric modulation of mGlu5. | Gass JT et al. | β | 2017 | β |
| Disorganized Amygdala Networks in Conduct-Disordered Juvenile Offenders With Callous-Unemotional Traits. | Aghajani M et al. | β | 2017 | β |
| Dissociable Role of Corticotropin Releasing Hormone Receptor Subtype 1 on Dopaminergic and D1 Dopaminoceptive Neurons in Cocaine Seeking Behavior. | Bernardi RE et al. | β | 2017 | β |
| Distinct roles for the deacetylase domain of HDAC3 in the hippocampus and medial prefrontal cortex in the formation and extinction of memory. | Alaghband Y et al. | β | 2017 | β |
| DNA Methylation Profiling of Human Prefrontal Cortex Neurons in Heroin Users Shows Significant Difference between Genomic Contexts of Hyper- and Hypomethylation and a Younger Epigenetic Age. | Kozlenkov A et al. | β | 2017 | β |
| Extinction of Contextual Cocaine Memories Requires Ca<sub>v</sub>1.2 within D1R-Expressing Cells and Recruits Hippocampal Ca<sub>v</sub>1.2-Dependent Signaling Mechanisms. | Burgdorf CE et al. | β | 2017 | β |
| Glutamate and Brain Glutaminases in Drug Addiction. | MΓ‘rquez J et al. | β | 2017 | β |
| Habitual Behavior Is Mediated by a Shift in Response-Outcome Encoding by Infralimbic Cortex. | Barker JM et al. | β | 2017 | β |
| How contexts promote and prevent relapse to drug seeking. | Khoo SY et al. | β | 2017 | β |
| Inactivation of the Prelimbic Cortex Impairs the Context-Induced Reinstatement of Ethanol Seeking. | Palombo P et al. | β | 2017 | β |
| Individual differences in fear extinction and anxiety-like behavior. | King G et al. | β | 2017 | β |
| Integration of contextual cues into memory depends on "prefrontal" N-methyl-D-aspartate receptors. | Starosta S et al. | β | 2017 | β |
| Intermittent Ethanol during Adolescence Leads to Lasting Behavioral Changes in Adulthood and Alters Gene Expression and Histone Methylation in the PFC. | Wolstenholme JT et al. | β | 2017 | β |
| Intra-accumbal Cannabinoid Agonist Attenuated Reinstatement but not Extinction Period of Morphine-Induced Conditioned Place Preference; Evidence for Different Characteristics of Extinction Period and Reinstatement. | Khaleghzadeh-Ahangar H et al. | β | 2017 | β |
| Neural responses to negative outcomes predict success in community-based substance use treatment. | Forster SE et al. | β | 2017 | β |
| Neuroanatomical Substrates of Rodent Social Behavior: The Medial Prefrontal Cortex and Its Projection Patterns. | Ko J | β | 2017 | β |
| Neurobiology of comorbid post-traumatic stress disorder and alcohol-use disorder. | Gilpin NW et al. | β | 2017 | β |
| PERK signalling pathway mediates single prolonged stress-induced dysfunction of medial prefrontal cortex neurons. | Wen L et al. | β | 2017 | β |
| Post-Learning Sleep Transiently Boosts Context Specific Operant Extinction Memory. | Borquez M et al. | β | 2017 | β |
| Prefrontal Cortex K<sub>Ca</sub>2 Channels Regulate mGlu<sub>5</sub>-Dependent Plasticity and Extinction of Alcohol-Seeking Behavior. | Cannady R et al. | β | 2017 | β |
| Prefrontal Dopaminergic Mechanisms of Extinction in Adolescence Compared to Adulthood in Rats. | Zbukvic IC et al. | β | 2017 | β |
| Regulation and function of MeCP2 Ser421 phosphorylation in U50488-induced conditioned place aversion in mice. | Zannas AS et al. | β | 2017 | β |
| Regulation of Alcohol Extinction and Cue-Induced Reinstatement by Specific Projections among Medial Prefrontal Cortex, Nucleus Accumbens, and Basolateral Amygdala. | Keistler CR et al. | β | 2017 | β |
| Reprogramming of mPFC transcriptome and function in alcohol dependence. | Heilig M et al. | β | 2017 | β |
| RETRACTED: Exploring the mechanism by which accumbal deep brain stimulation attenuates morphine-induced reinstatement through manganese-enhanced MRI and pharmacological intervention. | Zhang L et al. | β | 2017 | β |
| Role of dopamine projections from ventral tegmental area to nucleus accumbens and medial prefrontal cortex in reinforcement behaviors assessed using optogenetic manipulation. | Han X et al. | β | 2017 | β |
| Role of TAAR1 within the Subregions of the Mesocorticolimbic Dopaminergic System in Cocaine-Seeking Behavior. | Liu JF et al. | β | 2017 | β |
| Single Prazosin Infusion in Prelimbic Cortex Fosters Extinction of Amphetamine-Induced Conditioned Place Preference. | Latagliata EC et al. | β | 2017 | β |
| Stable immediate early gene expression patterns in medial prefrontal cortex and striatum after long-term cocaine self-administration. | Gao P et al. | β | 2017 | β |
| Successful pharmacotherapy for the treatment of severe feeding aversion with mechanistic insights from cross-species neuronal remodeling. | Sharp WG et al. | β | 2017 | β |
| Synaptic Regulation of a Thalamocortical Circuit Controls Depression-Related Behavior. | Miller OH et al. | β | 2017 | β |
| Transgenic autoinhibition of p21-activated kinase exacerbates synaptic impairments and fronto-dependent behavioral deficits in an animal model of Alzheimer's disease. | Bories C et al. | β | 2017 | β |
| Vagus nerve stimulation reduces cocaine seeking and alters plasticity in the extinction network. | Childs JE et al. | β | 2017 | β |
| Ventral, but not dorsal, hippocampus inactivation impairs reward memory expression and retrieval in contexts defined by proximal cues. | Riaz S et al. | β | 2017 | β |
| WHEN SCIENTIFIC PARADIGMS LEAD TO TUNNEL VISION: LESSONS FROM THE STUDY OF FEAR. | ParΓ© D et al. | β | 2017 | β |
| Abnormal functional architecture of amygdala-centered networks in adolescent posttraumatic stress disorder. | Aghajani M et al. | β | 2016 | β |
| A Dynamic Bayesian Model for Characterizing Cross-Neuronal Interactions During Decision-Making. | Zhou B et al. | β | 2016 | β |
| A GABAergic Projection from the Centromedial Nuclei of the Amygdala to Ventromedial Prefrontal Cortex Modulates Reward Behavior. | Seo DO et al. | β | 2016 | β |
| Altered behavior and neural activity in conspecific cagemates co-housed with mouse models of brain disorders. | Yang H et al. | β | 2016 | β |
| Altered consolidation of extinction-like inhibitory learning in genotype-specific dysfunctional coping fostered by chronic stress in mice. | Campus P et al. | β | 2016 | β |
| Bidirectional modulation of anxiety-related and social behaviors by amygdala projections to the medial prefrontal cortex. | Felix-Ortiz AC et al. | β | 2016 | β |
| Bidirectional Modulation of Extinction of Drug Seeking by Deep Brain Stimulation of the Ventral Striatum. | MartΓnez-Rivera FJ et al. | β | 2016 | β |
| Biologically based neural circuit modelling for the study of fear learning and extinction. | Nair SS et al. | β | 2016 | β |
| Caught in the Net: Perineuronal Nets and Addiction. | Slaker M et al. | β | 2016 | β |
| Chemogenetic Activation of an Extinction Neural Circuit Reduces Cue-Induced Reinstatement of Cocaine Seeking. | Augur IF et al. | β | 2016 | β |
| Cocaine Self-Administration Elevates GluN2B within dmPFC Mediating Heightened Cue-Elicited Operant Responding. | Szumlinski KK et al. | β | 2016 | β |
| Compulsivity in obsessive-compulsive disorder and addictions. | Figee M et al. | β | 2016 | β |
| Cortico-Basal Ganglia Circuit Function in Psychiatric Disease. | Gunaydin LA et al. | β | 2016 | β |
| Distinct Fos-Expressing Neuronal Ensembles in the Ventromedial Prefrontal Cortex Mediate Food Reward and Extinction Memories. | Warren BL et al. | β | 2016 | β |
| Effects of Trace Amine-associated Receptor 1 Agonists on the Expression, Reconsolidation, and Extinction of Cocaine Reward Memory. | Liu JF et al. | β | 2016 | β |
| GABA-Mediated Inactivation of Medial Prefrontal and Agranular Insular Cortex in the Rat: Contrasting Effects on Hunger- and Palatability-Driven Feeding. | Baldo BA et al. | β | 2016 | β |
| Going and stopping: Dichotomies in behavioral control by the prefrontal cortex. | Gourley SL et al. | β | 2016 | β |
| Hyperresponsiveness of the Neural Fear Network During Fear Conditioning and Extinction Learning in Male Cocaine Users. | Kaag AM et al. | β | 2016 | β |
| Impaired Functional Connectivity in the Prefrontal Cortex: A Mechanism for Chronic Stress-Induced Neuropsychiatric Disorders. | NegrΓ³n-Oyarzo I et al. | β | 2016 | β |
| Lateral, not medial, prefrontal cortex contributes to punishment and aversive instrumental learning. | Jean-Richard-Dit-Bressel P et al. | β | 2016 | β |
| Local Control of Extracellular Dopamine Levels in the Medial Nucleus Accumbens by a Glutamatergic Projection from the Infralimbic Cortex. | Quiroz C et al. | β | 2016 | β |
| Minocycline attenuates interferon-Ξ±-induced impairments in rat fear extinction. | Bi Q et al. | β | 2016 | β |
| Neuroscience of learning and memory for addiction medicine: from habit formation to memory reconsolidation. | Torregrossa MM et al. | β | 2016 | β |
| Nonmuscle myosin IIB as a therapeutic target for the prevention of relapse to methamphetamine use. | Young EJ et al. | β | 2016 | β |
| Norepinephrine in prelimbic cortex delays extinction of amphetamine-induced conditioned place preference. | Latagliata EC et al. | β | 2016 | β |
| NPY+-, but not PV+- GABAergic neurons mediated long-range inhibition from infra- to prelimbic cortex. | Saffari R et al. | β | 2016 | β |
| Orexin-1 receptor signalling in the prelimbic cortex and ventral tegmental area regulates cue-induced reinstatement of ethanol-seeking in iP rats. | Brown RM et al. | β | 2016 | β |
| Orexin/hypocretin receptor 1 signaling mediates Pavlovian cue-food conditioning and extinction. | Keefer SE et al. | β | 2016 | β |
| Pharmacological reduction of adult hippocampal neurogenesis modifies functional brain circuits in mice exposed to a cocaine conditioned place preference paradigm. | Castilla-Ortega E et al. | β | 2016 | β |
| Prefrontal cortical BDNF: A regulatory key in cocaine- and food-reinforced behaviors. | Pitts EG et al. | β | 2016 | β |
| Regulation of the Hypothalamic-Pituitary-Adrenocortical Stress Response. | Herman JP et al. | β | 2016 | β |
| Resveratrol fails to affect cocaine conditioned place preference behavior, but alleviates anxiety-like behaviors in cocaine withdrawn rats. | Hu P et al. | β | 2016 | β |
| Role of Dopamine 2 Receptor in Impaired Drug-Cue Extinction in Adolescent Rats. | Zbukvic IC et al. | β | 2016 | β |
| Selective Control of Fear Expression by Optogenetic Manipulation of Infralimbic Cortex after Extinction. | Kim HS et al. | β | 2016 | β |
| Specific Targeting of the Basolateral Amygdala to Projectionally Defined Pyramidal Neurons in Prelimbic and Infralimbic Cortex. | Cheriyan J et al. | β | 2016 | β |
| Systematic Review on Post-Traumatic Stress Disorder Among Survivors of the Wenchuan Earthquake. | Hong C et al. | β | 2016 | β |
| The metabotropic glutamate 5 receptor is necessary for extinction of cocaine-associated cues. | Perry CJ et al. | β | 2016 | β |
| The neurocircuitry of remote cued fear memory. | Bergstrom HC | β | 2016 | β |
| The Nucleus Accumbens: Mechanisms of Addiction across Drug Classes Reflect the Importance of Glutamate Homeostasis. | Scofield MD et al. | β | 2016 | β |
| The role of working memory and declarative memory in trace conditioning. | Connor DA et al. | β | 2016 | β |
| Trait Anxiety Modulates Brain Activity during Performance of Verbal Fluency Tasks. | Gawda B et al. | β | 2016 | β |
| Traumatic stress causes distinctive effects on fear circuit catecholamines and the fear extinction profile in a rodent model of posttraumatic stress disorder. | Lin CC et al. | β | 2016 | β |
| Using model systems to understand errant plasticity mechanisms in psychiatric disorders. | Averbeck BB et al. | β | 2016 | β |
| Ventral medial prefrontal cortex (vmPFC) as a target of the dorsolateral prefrontal modulation by transcranial direct current stimulation (tDCS) in drug addiction. | Nakamura-Palacios EM et al. | β | 2016 | β |
| Ventral Pallidum Neurons Encode Incentive Value and Promote Cue-Elicited Instrumental Actions. | Richard JM et al. | β | 2016 | β |
| Viewpoints: Dialogues on the functional role of the ventromedial prefrontal cortex. | Delgado MR et al. | β | 2016 | β |
| Amphetamine in adolescence disrupts the development of medial prefrontal cortex dopamine connectivity in a DCC-dependent manner. | Reynolds LM et al. | β | 2015 | β |
| Amphetamine sensitization is accompanied by an increase in prelimbic cortex activity. | Aguilar-Rivera MI et al. | β | 2015 | β |
| Anisomycin in the medial prefrontal cortex reduces reconsolidation of cocaine-associated memories in the rat self-administration model. | Sorg BA et al. | β | 2015 | β |
| Blocking NMDA-receptors in the pigeon's "prefrontal" caudal nidopallium impairs appetitive extinction learning in a sign-tracking paradigm. | Lengersdorf D et al. | β | 2015 | β |
| Brain activation induced by voluntary alcohol and saccharin drinking in rats assessed with manganese-enhanced magnetic resonance imaging. | Dudek M et al. | β | 2015 | β |
| Brain-derived neurotrophic factor and addiction: Pathological versus therapeutic effects on drug seeking. | Barker JM et al. | β | 2015 | β |
| Cocaine self-administration enhances excitatory responses of pyramidal neurons in the rat medial prefrontal cortex to human immunodeficiency virus-1 Tat. | Wayman WN et al. | β | 2015 | β |
| Commonalities and Distinctions Among Mechanisms of Addiction to Alcohol and Other Drugs. | Ozburn AR et al. | β | 2015 | β |
| Context-controlled nicotine-induced changes in the labeling of serotonin (5-HT)2A and 5-HT2C receptors in the rat brain. | Zaniewska M et al. | β | 2015 | β |
| Context-induced reinstatement of methamphetamine seeking is associated with unique molecular alterations in Fos-expressing dorsolateral striatum neurons. | Rubio FJ et al. | β | 2015 | β |
| Control Over Stress Accelerates Extinction of Drug Seeking Via Prefrontal Cortical Activation. | Baratta MV et al. | β | 2015 | β |
| Cortical consequences of HIV-1 Tat exposure in rats are enhanced by chronic cocaine. | Wayman WN et al. | β | 2015 | β |
| Corticolimbic catecholamines in stress: a computational model of the appraisal of controllability. | Fiore VG et al. | β | 2015 | β |
| Corticostriatal circuitry and habitual ethanol seeking. | Barker JM et al. | β | 2015 | β |
| Differential roles of medial prefrontal subregions in the regulation of drug seeking. | Moorman DE et al. | β | 2015 | β |
| Dissociation of the Role of Infralimbic Cortex in Learning and Consolidation of Extinction of Recent and Remote Aversion Memory. | Awad W et al. | β | 2015 | β |
| Dorsal medial prefrontal cortex (MPFC) circuitry in rodent models of cocaine use: implications for drug addiction therapies. | Jasinska AJ et al. | β | 2015 | β |
| Epigenetics and memory: causes, consequences and treatments for post-traumatic stress disorder and addiction. | Pizzimenti CL et al. | β | 2015 | β |
| Extinction and reinstatement to cocaine-associated cues in male and female juvenile rats and the role of D1 dopamine receptor. | Brenhouse HC et al. | β | 2015 | β |
| Gender effects in alcohol dependence: an fMRI pilot study examining affective processing. | Padula CB et al. | β | 2015 | β |
| Inactivating the infralimbic but not prelimbic medial prefrontal cortex facilitates the extinction of appetitive Pavlovian conditioning in Long-Evans rats. | Mendoza J et al. | β | 2015 | β |
| Increased prefrontal cortex neurogranin enhances plasticity and extinction learning. | Zhong L et al. | β | 2015 | β |
| Infralimbic prefrontal cortex interacts with nucleus accumbens shell to unmask expression of outcome-selective Pavlovian-to-instrumental transfer. | Keistler C et al. | β | 2015 | β |
| Investigating the phenomenological matrix of mindfulness-related practices from a neurocognitive perspective. | Lutz A et al. | β | 2015 | β |
| Long-range GABAergic neurons in the prefrontal cortex modulate behavior. | Bravo-Rivera C et al. | β | 2015 | β |
| Losing Control: Excessive Alcohol Seeking after Selective Inactivation of Cue-Responsive Neurons in the Infralimbic Cortex. | Pfarr S et al. | β | 2015 | β |
| Methylphenidate and atomoxetine inhibit social play behavior through prefrontal and subcortical limbic mechanisms in rats. | Achterberg EJ et al. | β | 2015 | β |
| Monoacylglycerol lipase (MGLL) polymorphism rs604300 interacts with childhood adversity to predict cannabis dependence symptoms and amygdala habituation: Evidence from an endocannabinoid system-level analysis. | Carey CE et al. | β | 2015 | β |
| Neural mechanisms regulating different forms of risk-related decision-making: Insights from animal models. | Orsini CA et al. | β | 2015 | β |
| Neuronal Circuits for Fear Expression and Recovery: Recent Advances and Potential Therapeutic Strategies. | Dejean C et al. | β | 2015 | β |
| On and Off switches in the brain. | Moustafa AA | β | 2015 | β |
| Pharmacological disruption of maladaptive memory. | Taylor JR et al. | β | 2015 | β |
| Prefrontal neurons encode context-based response execution and inhibition in reward seeking and extinction. | Moorman DE et al. | β | 2015 | β |
| Removal of perineuronal nets in the medial prefrontal cortex impairs the acquisition and reconsolidation of a cocaine-induced conditioned place preference memory. | Slaker M et al. | β | 2015 | β |
| Role of corticostriatal circuits in context-induced reinstatement of drug seeking. | Marchant NJ et al. | β | 2015 | β |
| Role of the ventral tegmental area in methamphetamine extinction: AMPA receptor-mediated neuroplasticity. | Chen HT et al. | β | 2015 | β |
| Sufficiency of Mesolimbic Dopamine Neuron Stimulation for the Progression to Addiction. | Pascoli V et al. | β | 2015 | β |
| The central amygdala as an integrative hub for anxiety and alcohol use disorders. | Gilpin NW et al. | β | 2015 | β |
| The influence of acute stress on the regulation of conditioned fear. | Raio CM et al. | β | 2015 | β |
| The Role of the Medial Prefrontal Cortex in the Conditioning and Extinction of Fear. | Giustino TF et al. | β | 2015 | β |
| Vagus Nerve Stimulation as a Tool to Induce Plasticity in Pathways Relevant for Extinction Learning. | Childs JE et al. | β | 2015 | β |
| Activation of prefrontal cortical parvalbumin interneurons facilitates extinction of reward-seeking behavior. | Sparta DR et al. | β | 2014 | β |
| Adolescent alcohol exposure reduces behavioral flexibility, promotes disinhibition, and increases resistance to extinction of ethanol self-administration in adulthood. | Gass JT et al. | β | 2014 | β |
| Amygdala and bed nucleus of the stria terminalis circuitry: Implications for addiction-related behaviors. | Stamatakis AM et al. | β | 2014 | β |
| At the crossroads: the intersection of substance use disorders, anxiety disorders, and posttraumatic stress disorder. | Ruglass LM et al. | β | 2014 | β |
| A unifying model of the role of the infralimbic cortex in extinction and habits. | Barker JM et al. | β | 2014 | β |
| BDNF-TrkB receptor regulation of distributed adult neural plasticity, memory formation, and psychiatric disorders. | Andero R et al. | β | 2014 | β |
| Behavioral and neurobiological mechanisms of extinction in Pavlovian and instrumental learning. | Todd TP et al. | β | 2014 | β |
| Bidirectional effects of inhibiting or potentiating NMDA receptors on extinction after cocaine self-administration in rats. | Hafenbreidel M et al. | β | 2014 | β |
| Biological substrates of addiction. | Joffe ME et al. | β | 2014 | β |
| Blockade of mGluR5 in the nucleus accumbens shell but not core attenuates heroin seeking behavior in rats. | Lou ZZ et al. | β | 2014 | β |
| Bridging the interval: theory and neurobiology of trace conditioning. | Raybuck JD et al. | β | 2014 | β |
| CB1 augments mGluR5 function in medial prefrontal cortical neurons to inhibit amygdala hyperactivity in an arthritis pain model. | Ji G et al. | β | 2014 | β |
| Cortico-amygdala coupling as a marker of early relapse risk in cocaine-addicted individuals. | McHugh MJ et al. | β | 2014 | β |
| Corticosteroid-endocannabinoid loop supports decrease of fear-conditioned response in rats. | Bitencourt RM et al. | β | 2014 | β |
| Depletion of perineuronal nets in the amygdala to enhance the erasure of drug memories. | Xue YX et al. | β | 2014 | β |
| Dopamine and extinction: a convergence of theory with fear and reward circuitry. | Abraham AD et al. | β | 2014 | β |
| Dorsal hippocampus inactivation impairs spontaneous recovery of Pavlovian magazine approach responding in rats. | Campese VD et al. | β | 2014 | β |
| Enhancement of extinction learning attenuates ethanol-seeking behavior and alters plasticity in the prefrontal cortex. | Gass JT et al. | β | 2014 | β |
| Epigenetic and pharmacological regulation of 5HT3 receptors controls compulsive ethanol seeking in mice. | Barker JM et al. | β | 2014 | β |
| Error-related functional connectivity of the thalamus in cocaine dependence. | Zhang S et al. | β | 2014 | β |
| Excitotoxic lesions of the infralimbic, but not prelimbic cortex facilitate reversal of appetitive discriminative context conditioning: the role of the infralimbic cortex in context generalization. | Ashwell R et al. | β | 2014 | β |
| From non-pharmacological treatments for post-traumatic stress disorder to novel therapeutic targets. | Hendriksen H et al. | β | 2014 | β |
| Goal-directed learning and obsessive-compulsive disorder. | Gillan CM et al. | β | 2014 | β |
| Hippocampal neurogenesis protects against cocaine-primed relapse. | Deschaux O et al. | β | 2014 | β |
| Histone-mediated epigenetics in addiction. | Hitchcock LN et al. | β | 2014 | β |
| Impaired adrenergic-mediated plasticity of prefrontal cortical glutamate synapses in rats with developmental disruption of the ventral hippocampus. | Bhardwaj SK et al. | β | 2014 | β |
| Inactivation of the prelimbic rather than infralimbic cortex impairs acquisition and expression of formalin-induced conditioned place avoidance. | Jiang ZC et al. | β | 2014 | β |
| Investigating habits: strategies, technologies and models. | Smith KS et al. | β | 2014 | β |
| Learned stressor resistance requires extracellular signal-regulated kinase in the prefrontal cortex. | Christianson JP et al. | β | 2014 | β |
| Medial prefrontal cortex inactivation attenuates the diurnal rhythm in amphetamine reward. | Baltazar RM et al. | β | 2014 | β |
| Modulating fear extinction memory by manipulating SK potassium channels in the infralimbic cortex. | Criado-Marrero M et al. | β | 2014 | β |
| Modulation of defensive behavior by Transient Receptor Potential Vanilloid Type-1 (TRPV1) channels. | Aguiar DC et al. | β | 2014 | β |
| Nicotine self-administration induces CB1-dependent LTP in the bed nucleus of the stria terminalis. | Reisiger AR et al. | β | 2014 | β |
| Okadaic acid blocks the effects of 5-aza-2-deoxycytidine on consolidation, acquisition and retrieval of morphine-induced place preference in rats. | Zhang JJ et al. | β | 2014 | β |
| Olfactory systems and neural circuits that modulate predator odor fear. | Takahashi LK | β | 2014 | β |
| Optogenetic dissection of amygdala functioning. | Lalumiere RT | β | 2014 | β |
| Optogenetic dissection of medial prefrontal cortex circuitry. | Riga D et al. | β | 2014 | β |
| Orbitofrontal cortical neurons encode expectation-driven initiation of reward-seeking. | Moorman DE et al. | β | 2014 | β |
| Oxytocin in the medial prefrontal cortex regulates maternal care, maternal aggression and anxiety during the postpartum period. | Sabihi S et al. | β | 2014 | β |
| Oxytocin's role in anxiety: a critical appraisal. | MacDonald K et al. | β | 2014 | β |
| Postnatal day 2 to 11 constitutes a 5-HT-sensitive period impacting adult mPFC function. | Rebello TJ et al. | β | 2014 | β |
| Probing NMDA receptor GluN2A and GluN2B subunit expression and distribution in cortical neurons. | Balsara RD et al. | β | 2014 | β |
| Projections from the dorsal peduncular cortex to the trigeminal subnucleus caudalis (medullary dorsal horn) and other lower brainstem areas in rats. | Akhter F et al. | β | 2014 | β |
| Psychological and neural mechanisms of experimental extinction: a selective review. | Delamater AR et al. | β | 2014 | β |
| Rapid, transient synaptic plasticity in addiction. | Gipson CD et al. | β | 2014 | β |
| Reinforcing and neural activating effects of norharmane, a non-nicotine tobacco constituent, alone and in combination with nicotine. | Arnold MM et al. | β | 2014 | β |
| Retrieval-induced NMDA receptor-dependent Arc expression in two models of cocaine-cue memory. | Alaghband Y et al. | β | 2014 | β |
| Social housing conditions influence morphine dependence and the extinction of morphine place preference in adolescent mice. | Bates ML et al. | β | 2014 | β |
| The effects of acute stress exposure on striatal activity during Pavlovian conditioning with monetary gains and losses. | Lewis AH et al. | β | 2014 | β |
| The learning of fear extinction. | Furini C et al. | β | 2014 | β |
| The neural correlates of regulating positive and negative emotions in medication-free major depression. | Greening SG et al. | β | 2014 | β |
| The role of ventral and dorsal striatum mGluR5 in relapse to cocaine-seeking and extinction learning. | Knackstedt LA et al. | β | 2014 | β |
| Time-dependent effects of prazosin on the development of methamphetamine conditioned hyperactivity and context-specific sensitization in mice. | White AO et al. | β | 2014 | β |
| Transient inactivation of the pigeon hippocampus or the nidopallium caudolaterale during extinction learning impairs extinction retrieval in an appetitive conditioning paradigm. | Lengersdorf D et al. | β | 2014 | β |
| A causal link between prediction errors, dopamine neurons and learning. | Steinberg EE et al. | β | 2013 | β |
| A dual operator view of habitual behavior reflecting cortical and striatal dynamics. | Smith KS et al. | β | 2013 | β |
| Alterations in expression and phosphorylation of GluA1 receptors following cocaine-cue extinction learning. | Nic Dhonnchadha BΓ et al. | β | 2013 | β |
| A randomized, placebo-controlled laboratory study of the effects of D-cycloserine on craving in cocaine-dependent individuals. | Price KL et al. | β | 2013 | β |
| Are AMPA receptor positive allosteric modulators potential pharmacotherapeutics for addiction? | Watterson LR et al. | β | 2013 | β |
| A role for the prefrontal cortex in heroin-seeking after forced abstinence by adult male rats but not adolescents. | Doherty JM et al. | β | 2013 | β |
| Comorbidities and continuities as ontogenic processes: toward a developmental spectrum model of externalizing psychopathology. | Beauchaine TP et al. | β | 2013 | β |
| Comparison of the MK-801-induced increase in non-rewarded appetitive responding with dopamine agonists and locomotor activity in rats. | Davis-MacNevin PL et al. | β | 2013 | β |
| Cortical activation of accumbens hyperpolarization-active NMDARs mediates aversion-resistant alcohol intake. | Seif T et al. | β | 2013 | β |
| dcc orchestrates the development of the prefrontal cortex during adolescence and is altered in psychiatric patients. | Manitt C et al. | β | 2013 | β |
| Differential roles of the prefrontal cortical subregions and basolateral amygdala in compulsive cocaine seeking and relapse after voluntary abstinence in rats. | Pelloux Y et al. | β | 2013 | β |
| Effect of D-cycloserine in conjunction with fear extinction training on extracellular signal-regulated kinase activation in the medial prefrontal cortex and amygdala in rat. | Gupta SC et al. | β | 2013 | β |
| Impaired memory and reduced sensitivity to the circadian period lengthening effects of methamphetamine in mice selected for high methamphetamine consumption. | Olsen RH et al. | β | 2013 | β |
| Inhibition of glycine transporter-1 reduces cue-induced nicotine-seeking, but does not promote extinction of conditioned nicotine cue responding in the rat. | Cervo L et al. | β | 2013 | β |
| Lack of increased immediate early gene expression in rats reinstating cocaine-seeking behavior to discrete sensory cues. | Riedy MD et al. | β | 2013 | β |
| Learning to forget: manipulating extinction and reconsolidation processes to treat addiction. | Torregrossa MM et al. | β | 2013 | β |
| Let's get physical: a contemporary review of the anxiolytic effects of exercise for anxiety and its disorders. | Asmundson GJ et al. | β | 2013 | β |
| Molecular mechanisms mediating a deficit in recall of fear extinction in adult mice exposed to cocaine in utero. | Kabir ZD et al. | β | 2013 | β |
| Neural mechanisms of pain and alcohol dependence. | Apkarian AV et al. | β | 2013 | β |
| Neurobiological dissociation of retrieval and reconsolidation of cocaine-associated memory. | Otis JM et al. | β | 2013 | β |
| Olanzapine treatment of adolescent rats alters adult reward behaviour and nucleus accumbens function. | Vinish M et al. | β | 2013 | β |
| Olanzapine treatment of adolescent rats causes enduring specific memory impairments and alters cortical development and function. | Milstein JA et al. | β | 2013 | β |
| Prefrontal cortex modulates desire and dread generated by nucleus accumbens glutamate disruption. | Richard JM et al. | β | 2013 | β |
| Prefrontal cortical kappa-opioid receptor modulation of local neurotransmission and conditioned place aversion. | Tejeda HA et al. | β | 2013 | β |
| Prefrontal synaptic markers of cocaine addiction-like behavior in rats. | Kasanetz F et al. | β | 2013 | β |
| Recent developments in animal models of drug relapse. | Marchant NJ et al. | β | 2013 | β |
| Rescuing cocaine-induced prefrontal cortex hypoactivity prevents compulsive cocaine seeking. | Chen BT et al. | β | 2013 | β |
| Role of medial prefrontal cortex Narp in the extinction of morphine conditioned place preference. | Blouin AM et al. | β | 2013 | β |
| Role of orexin/hypocretin in conditioned sucrose-seeking in rats. | Cason AM et al. | β | 2013 | β |
| Social play behavior in adolescent rats is mediated by functional activity in medial prefrontal cortex and striatum. | van Kerkhof LW et al. | β | 2013 | β |
| Substituting a long-acting dopamine uptake inhibitor for cocaine prevents relapse to cocaine seeking. | VelΓ‘zquez-SΓ‘nchez C et al. | β | 2013 | β |
| Synaptic plasticity in depression: molecular, cellular and functional correlates. | Marsden WN | β | 2013 | β |
| Targeting cocaine versus heroin memories: divergent roles within ventromedial prefrontal cortex. | Peters J et al. | β | 2013 | β |
| The Plasticity of Extinction: Contribution of the Prefrontal Cortex in Treating Addiction through Inhibitory Learning. | Gass JT et al. | β | 2013 | β |
| The reinstatement model of drug relapse: recent neurobiological findings, emerging research topics, and translational research. | Bossert JM et al. | β | 2013 | β |
| The role of medial prefrontal cortex in extinction and reinstatement of alcohol-seeking in rats. | Willcocks AL et al. | β | 2013 | β |
| The touchscreen operant platform for assessing executive function in rats and mice. | Mar AC et al. | β | 2013 | β |
| Using optogenetics to study habits. | Smith KS et al. | β | 2013 | β |
| Ventromedial prefrontal cortex pyramidal cells have a temporal dynamic role in recall and extinction of cocaine-associated memory. | Van den Oever MC et al. | β | 2013 | β |
| Activation and role of the medial prefrontal cortex (mPFC) in extinction of ethanol-induced associative learning in mice. | Groblewski PA et al. | β | 2012 | β |
| A memory retrieval-extinction procedure to prevent drug craving and relapse. | Xue YX et al. | β | 2012 | β |
| Brain activation during fear conditioning in humans depends on genetic variations related to functioning of the hypothalamic-pituitary-adrenal axis: first evidence from two independent subsamples. | Ridder S et al. | β | 2012 | β |
| Common liability to addiction and "gateway hypothesis": theoretical, empirical and evolutionary perspective. | Vanyukov MM et al. | β | 2012 | β |
| Comparison of the MK-801-induced appetitive extinction deficit with pressing for reward and associated pERK1/2 staining in prefrontal cortex and nucleus accumbens. | Holahan MR et al. | β | 2012 | β |
| Context, emotion, and the strategic pursuit of goals: interactions among multiple brain systems controlling motivated behavior. | Gruber AJ et al. | β | 2012 | β |
| Cue exposure and response prevention with heavy smokers: a laboratory-based randomised placebo-controlled trial examining the effects of D-cycloserine on cue reactivity and attentional bias. | Kamboj SK et al. | β | 2012 | β |
| Differential involvement of prelimbic and infralimbic medial prefrontal cortex in discrete cue-induced reinstatement of 3,4-methylenedioxymethamphetamine (MDMA; ecstasy) seeking in rats. | Ball KT et al. | β | 2012 | β |
| Eating in eating disorders. | Treasure J et al. | β | 2012 | β |
| Enhanced extinction of cocaine seeking in brain-derived neurotrophic factor Val66Met knock-in mice. | Briand LA et al. | β | 2012 | β |
| Extinction of aversive memories associated with morphine withdrawal requires ERK-mediated epigenetic regulation of brain-derived neurotrophic factor transcription in the rat ventromedial prefrontal cortex. | Wang WS et al. | β | 2012 | β |
| Facilitated extinction of morphine conditioned place preference with Tat-GluA2(3Y) interference peptide. | Dias C et al. | β | 2012 | β |
| Functional anatomy of ventromedial prefrontal cortex: implications for mood and anxiety disorders. | Myers-Schulz B et al. | β | 2012 | β |
| Inactivation of the basolateral amygdala during opiate reward learning disinhibits prelimbic cortical neurons and modulates associative memory extinction. | Sun N et al. | β | 2012 | β |
| Inhibiting glycine transporter-1 facilitates cocaine-cue extinction and attenuates reacquisition of cocaine-seeking behavior. | Nic Dhonnchadha BΓ et al. | β | 2012 | β |
| Methylphenidate enhances extinction of contextual fear. | Abraham AD et al. | β | 2012 | β |
| Multiple sites of extinction for a single learned response. | Kalmbach BE et al. | β | 2012 | β |
| Neural circuit competition in cocaine-seeking: roles of the infralimbic cortex and nucleus accumbens shell. | LaLumiere RT et al. | β | 2012 | β |
| Neurocircuitry for modeling drug effects. | Noori HR et al. | β | 2012 | β |
| Norepinephrine and dopamine modulate impulsivity on the five-choice serial reaction time task through opponent actions in the shell and core sub-regions of the nucleus accumbens. | Economidou D et al. | β | 2012 | β |
| Prazosin differentially affects extinction of cocaine conditioned place preference on the basis of dose and initial preference. | Bernardi RE et al. | β | 2012 | β |
| Prelimbic BDNF and TrkB signaling regulates consolidation of both appetitive and aversive emotional learning. | Choi DC et al. | β | 2012 | β |
| PTSD and gene variants: new pathways and new thinking. | Skelton K et al. | β | 2012 | β |
| Reversible online control of habitual behavior by optogenetic perturbation of medial prefrontal cortex. | Smith KS et al. | β | 2012 | β |
| Role of projections from ventral medial prefrontal cortex to nucleus accumbens shell in context-induced reinstatement of heroin seeking. | Bossert JM et al. | β | 2012 | β |
| Sources of inputs to the anterior and posterior aspects of the paraventricular nucleus of the thalamus. | Li S et al. | β | 2012 | β |
| The BDNF Val66Met polymorphism impairs synaptic transmission and plasticity in the infralimbic medial prefrontal cortex. | Pattwell SS et al. | β | 2012 | β |
| The hypothalamus and the neurobiology of drug seeking. | Marchant NJ et al. | β | 2012 | β |
| The role of medial prefrontal cortex in memory and decision making. | Euston DR et al. | β | 2012 | β |
| The synaptic pathology of drug addiction. | Van den Oever MC et al. | β | 2012 | β |
| Ventromedial prefrontal-subcortical systems and the generation of affective meaning. | Roy M et al. | β | 2012 | β |
| Withdrawal-associated increases and decreases in functional neural connectivity associated with altered emotional regulation in alcoholism. | O'Daly OG et al. | β | 2012 | β |
| Aberrant learning and memory in addiction. | Torregrossa MM et al. | β | 2011 | β |
| Animal models of neuropsychiatric disorders. | Fernando AB et al. | β | 2011 | β |
| Chronic stress modulation of prefrontal cortical NMDA receptor expression disrupts limbic structure-prefrontal cortex interaction. | Lee YA et al. | β | 2011 | β |
| Craving, context and the cortex. | George O et al. | β | 2011 | β |
| Damage of GABAergic neurons in the medial septum impairs spatial working memory and extinction of active avoidance: effects on proactive interference. | Pang KC et al. | β | 2011 | β |
| Dissociations between medial prefrontal cortical subregions in the modulation of learning and action. | Maddux JM et al. | β | 2011 | β |
| Dorsal-ventral distinction of chronic stress-induced electrophysiological alterations in the rat medial prefrontal cortex. | Lee YA et al. | β | 2011 | β |
| Effects of elevation of brain magnesium on fear conditioning, fear extinction, and synaptic plasticity in the infralimbic prefrontal cortex and lateral amygdala. | Abumaria N et al. | β | 2011 | β |
| Environmental enrichment confers stress resiliency to social defeat through an infralimbic cortex-dependent neuroanatomical pathway. | Lehmann ML et al. | β | 2011 | β |
| Extinction of drug seeking. | Millan EZ et al. | β | 2011 | β |
| From reactive to proactive and selective control: developing a richer model for stopping inappropriate responses. | Aron AR | β | 2011 | β |
| Glutamate receptors in extinction and extinction-based therapies for psychiatric illness. | Myers KM et al. | β | 2011 | β |
| Glutamatergic neuroplasticity in cocaine addiction. | Uys JD et al. | β | 2011 | β |
| Glutamatergic plasticity in medial prefrontal cortex and ventral tegmental area following extended-access cocaine self-administration. | Ghasemzadeh MB et al. | β | 2011 | β |
| Identification of kalirin-7 as a potential post-synaptic density signaling hub. | Kiraly DD et al. | β | 2011 | β |
| Inactivation of the infralimbic prefrontal cortex in rats reduces the influence of inappropriate habitual responding in a response-conflict task. | Haddon JE et al. | β | 2011 | β |
| mGluR5 positive allosteric modulation enhances extinction learning following cocaine self-administration. | Cleva RM et al. | β | 2011 | β |
| Opiate versus psychostimulant addiction: the differences do matter. | Badiani A et al. | β | 2011 | β |
| Periaqueductal gray c-Fos expression varies relative to the method of conditioned taste aversion extinction employed. | Mickley GA et al. | β | 2011 | β |
| Pharmacological enhancement of drug cue extinction learning: translational challenges. | Kantak KM et al. | β | 2011 | β |
| PKMΞΆ maintains drug reward and aversion memory in the basolateral amygdala and extinction memory in the infralimbic cortex. | He YY et al. | β | 2011 | β |
| Psychosocial stress is associated with in vivo dopamine release in human ventromedial prefrontal cortex: a positron emission tomography study using [ΒΉβΈF]fallypride. | Lataster J et al. | β | 2011 | β |
| Reward-related behavioral paradigms for addiction research in the mouse: performance of common inbred strains. | Lederle L et al. | β | 2011 | β |
| The mGluR5 Positive Allosteric Modulator CDPPB Does Not Alter Extinction or Contextual Reinstatement of Methamphetamine-Seeking Behavior in Rats. | Widholm JJ et al. | β | 2011 | β |
| The nexus between decision making and emotion regulation: a review of convergent neurocognitive substrates. | Mitchell DG | β | 2011 | β |
| The role of the medial prefrontal cortex in innate fear regulation in infants, juveniles, and adolescents. | Chan T et al. | β | 2011 | β |
| The role of the ventromedial prefrontal cortex in memory consolidation. | Nieuwenhuis IL et al. | β | 2011 | β |
| The use of cognitive enhancers in animal models of fear extinction. | Kaplan GB et al. | β | 2011 | β |
| Treatment of addiction and anxiety using extinction approaches: neural mechanisms and their treatment implications. | Kaplan GB et al. | β | 2011 | β |
| Ventral medial prefrontal cortex neuronal ensembles mediate context-induced relapse to heroin. | Bossert JM et al. | β | 2011 | β |
| A role for alpha-adrenergic receptors in extinction of conditioned fear and cocaine conditioned place preference. | Bernardi RE et al. | β | 2010 | β |
| Chronic nicotine exposure produces lateralized, age-dependent dendritic remodeling in the rodent basolateral amygdala. | Bergstrom HC et al. | β | 2010 | β |
| Dopamine-mediated MK-801-induced elevation in food-based extinction responding in rats and associated changes in region-specific phosphorylated ERK. | Holahan MR et al. | β | 2010 | β |
| Enhancing the salience of dullness: behavioral and pharmacological strategies to facilitate extinction of drug-cue associations in adolescent rats. | Brenhouse HC et al. | β | 2010 | β |
| Erasing fear memories with extinction training. | Quirk GJ et al. | β | 2010 | β |
| Extinction of drug- and withdrawal-paired cues in animal models: relevance to the treatment of addiction. | Myers KM et al. | β | 2010 | β |
| Extinction of drug cue reactivity in methamphetamine-dependent individuals. | Price KL et al. | β | 2010 | β |
| Extinction training after cocaine self-administration induces glutamatergic plasticity to inhibit cocaine seeking. | Knackstedt LA et al. | β | 2010 | β |
| Extracellular matrix plasticity and GABAergic inhibition of prefrontal cortex pyramidal cells facilitates relapse to heroin seeking. | Van den Oever MC et al. | β | 2010 | β |
| Glutamatergic targets for enhancing extinction learning in drug addiction. | Cleva RM et al. | β | 2010 | β |
| How the neurocircuitry and genetics of fear inhibition may inform our understanding of PTSD. | Jovanovic T et al. | β | 2010 | β |
| Impairment of contextual conditioned fear extinction after microinjection of alpha-1-adrenergic blocker prazosin into the medial prefrontal cortex. | Do-Monte FH et al. | β | 2010 | β |
| Inhibition of actin polymerization prevents cocaine-induced changes in spine morphology in the nucleus accumbens. | Toda S et al. | β | 2010 | β |
| Medial prefrontal cortex activity can disrupt the expression of stress response habituation. | Weinberg MS et al. | β | 2010 | β |
| Noradrenergic modulation of extinction learning and exposure therapy. | Mueller D et al. | β | 2010 | β |
| Overlapping neural systems mediating extinction, reversal and regulation of fear. | Schiller D et al. | β | 2010 | β |
| Reacquisition of heroin and cocaine place preference involves a memory consolidation process sensitive to systemic and intra-ventral tegmental area naloxone. | Sticht M et al. | β | 2010 | β |
| Role of the prefrontal cortex and nucleus accumbens in reinstating methamphetamine seeking. | Rocha A et al. | β | 2010 | β |
| Stimulation of medial prefrontal cortex serotonin 2C (5-HT(2C)) receptors attenuates cocaine-seeking behavior. | Pentkowski NS et al. | β | 2010 | β |
| Stress-induced obesity and the emotional nervous system. | Dallman MF | β | 2010 | β |
| The infralimbic cortex regulates the consolidation of extinction after cocaine self-administration. | LaLumiere RT et al. | β | 2010 | β |
| Trait and neurobiological correlates of individual differences in dream recall and dream content. | Blagrove M et al. | β | 2010 | β |
| When the medial prefrontal cortex fails: implications for extinction and posttraumatic stress disorder treatment. | Groblewski PA et al. | β | 2010 | β |
| Role of the bed nucleus of the stria terminalis in the control of ventral tegmental area dopamine neurons. | Jalabert M et al. | β | 2009 | β |