Allelic association of human dopamine D2 receptor gene in alcoholism.
paper
Cited
Public
Unavailable
- Authors
- Blum, K; Noble, E P; Sheridan, P J; Montgomery, A; Ritchie, T; Jagadeeswaran, P; Nogami, H; Briggs, A H; Cohn, J B
- Year
- 1990
- Journal
- JAMA
- PMID
- 1969501
In a blinded experiment, we report the first allelic association of the dopamine D2 receptor gene in alcoholism. From 70 brain samples of alcoholics and nonalcoholics, DNA was digested with restriction endonucleases and probed with a clone that contained the entire 3' coding exon, the polyadenylation signal, and approximately 16.4 kilobases of noncoding 3' sequence of the human dopamine D2 receptor gene (lambda hD2G1). In the present samples, the presence of A1 allele of the dopamine D2 receptor gene correctly classified 77% of alcoholics, and its absence classified 72% of nonalcoholics. The polymorphic pattern of this receptor gene suggests that a gene that confers susceptibility to at least one form of alcoholism is located on the q22-q23 region of chromosome 11.
No figures extracted from this document.
No chunks β full text not yet ingested.
No entities extracted from this document yet.
No uploaded files.
Not in any collection.
No citations found.
In this knowledge base
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Dopamine receptor sensitivity, cocaine-induced behaviors, and Pavlovian conditioned approach in male rats. | Amissah NK et al. | β | 2026 | β |
| Relationship Between Problematic Alcohol Use and Various Psychiatric Disorders: A Genetically Informed Study. | Lawford B et al. | β | 2026 | β |
| Targeted Therapeutic Intervention for Problematic Alcohol Use, Comorbid Depressive Disorder, and Schizophrenia: Response to Lawford and Norrie. | Myung W et al. | β | 2026 | β |
| A Comprehensive 4-layered <i>In Silico</i> Pharmacogenomics Analysis of the Genetic Addiction Risk Severity (GARS) Test: Strong Genetic Evidence Supporting GARS as a Novel Personalized Pre-addiction Assessment Tool in the Opioid Crisis Era. | Sharafshah A et al. | β | 2025 | β |
| A GWAS Meta-meta-analysis and In-depth Silico Pharmacogenomic Investigations in Identification of APOE and Other Genes Associated with Pain, Anti-inflammatory, and Immunomodulating Agents in Opioid Use Disorder (OUD) Derived from 14.91 M Subjects. | Sharafshah A et al. | β | 2025 | β |
| Dopamine receptor sensitivity and Pavlovian conditioned approach | Amissah NK et al. | β | 2025 | β |
| Exploring dopamine as the master regulator of brain circuitry and mental health genome. | Blum K et al. | β | 2025 | β |
| Is It Scientifically Possible To 'Cure" Reward Deficiency Syndrome (RDS) Via Transplice Molecular Genetic Technology? | Blum K et al. | β | 2025 | β |
| Multi-Locus Pro-Dopaminergic Restoration of Reward Brain Circuitry in Reward Deficiency Rescinds Mono-Pharmaceutical Targeting. | Blum K et al. | β | 2025 | β |
| Neurospirituality Connectome - Role in Neurology and Reward Deficiency Syndrome (RDS). | Blum K et al. | β | 2025 | β |
| Opioid-Induced Hyperalgesia and Inflammaging in the Management of Spine Pain: The Case for Genetically Directed Dopamine Homeostasis. | Lewandrowski KU et al. | β | 2025 | β |
| Precision Genomics: A Reality Having Universal Impact in a New Era of Psychiatry - Lessons Learned, Past and Present. | Blum K et al. | β | 2025 | β |
| Targeting pro-dopaminergic agonism to attenuate depression in patients displaying genetic/epigenetic predisposition to hypodopaminergia. | Lewandrowski KU et al. | β | 2025 | β |
| Theorizing The Role of Gama Type Endorphins in Schizophrenia and Alcoholism: Promoting Genetic Testing and Attempts at Inducing "Dopamine Homeostasis". | Blum K et al. | β | 2025 | β |
| Addictive Behavior and Evolutionary Adaptation: Mitigated through Genetic Addiction Risk Severity Early Identification and Awareness Integration Theory. | Zeine F et al. | β | 2024 | β |
| ANKK1 Is a Wnt/PCP Scaffold Protein for Neural F-ACTIN Assembly. | DomΓnguez-Berzosa L et al. | β | 2024 | β |
| Evaluation of the Relationship Between Dopamine Receptor D2 Gene TaqIA1 Polymorphism and Alcohol Dependence Risk. | Kumar P et al. | β | 2024 | β |
| Evidence Based Clinical Analytics Supporting the Genetic Addiction Risk Severity (GARS) Assessment to Early Identify Probands in Preaddiction. | Blum K et al. | β | 2024 | β |
| Gene Interaction of Dopaminergic Synaptic Pathway Genes in Attention-Deficit Hyperactivity Disorder: a Case-Control Study in Chinese Children. | Zhong L et al. | β | 2024 | β |
| Identification of stress-induced epigenetic methylation onto dopamine D2 gene and neurological and behavioral consequences. | Blum K et al. | β | 2024 | β |
| Is There a Natural, Non-addictive, and Non-anti-reward, Safe, Gene-based Solution to Treat Reward Deficiency Syndrome? KB220 Variants vs GLP-1 Analogs. | Modestino EJ et al. | β | 2024 | β |
| Molecular and Environmental Determinants of Addictive Substances. | Lorek M et al. | β | 2024 | β |
| Solving the Global Opioid Crisis: Incorporating Genetic Addiction Risk Assessment with Personalized Dopaminergic Homeostatic Therapy and Awareness Integration Therapy. | Zeine F et al. | β | 2024 | β |
| Summary Document Research on RDS Anti-addiction Modeling: Annotated Bibliography. | Blum K et al. | β | 2024 | β |
| The association of genetic polymorphisms within the dopaminergic system with nicotine dependence: A narrative review. | Yang J et al. | β | 2024 | β |
| "Weeding out" violence? Translational perspectives on the neuropsychobiological links between cannabis and aggression. | Bortolato M et al. | β | 2024 | β |
| Are We Getting High Cause the Thrill is Gone? | Blum K et al. | β | 2023 | β |
| Dopaminergic dysfunction: Role for genetic & epigenetic testing in the new psychiatry. | Blum K et al. | β | 2023 | β |
| Epigenetic Effects of Psychoactive Drugs. | Ahmed R et al. | β | 2023 | β |
| Evidence for the <i>DRD2</i> Gene as a Determinant of Reward Deficiency Syndrome (RDS). | Blum K et al. | β | 2023 | β |
| Futuristic Exploration of Addiction Neuroscience in the Genomic Era. | Blum K et al. | β | 2023 | β |
| Invited Expert Opinion- Bioinformatic and Limitation Directives to Help Adopt Genetic Addiction Risk Screening and Identify Preaddictive Reward Dysregulation: Required Analytic Evidence to Induce Dopamine Homeostatsis. | Blum K et al. | β | 2023 | β |
| Neurogenetics and Epigenetics of Loneliness. | Bowirrat A et al. | β | 2023 | β |
| Reward Deficiency Syndrome Solution System (RDSSS) A Genetically Driven Putative Inducer of "Dopamine Homeostasis" as a Futuristic Alternative to Enhance Rehabilitation Instead of Incarceration. | Blum K et al. | β | 2023 | β |
| "TO BE OR NOT TO BE" GWAS Ends the Controversy about the DRD2 Gene as a Determinant of Reward Deficiency Syndrome (RDS). | Blum K et al. | β | 2023 | β |
| Association between DRD2/ANKK1 TaqIA Allele Status and Striatal Dopamine D2/3 Receptor Availability in Alcohol Use Disorder. | Spitta G et al. | β | 2022 | β |
| Atlas of type 2 dopamine receptors in the human brain: Age and sex dependent variability in a large PET cohort. | MalΓ©n T et al. | β | 2022 | β |
| Dopaminylation in Psychostimulant Use Disorder Protects Against Psychostimulant Seeking Behavior by Normalizing Nucleus Accumbens (NAc) Dopamine Expression. | Blum K et al. | β | 2022 | β |
| Frequency of the Dopamine Receptor D3 (rs6280) vs. Opioid Receptor Β΅1 (rs1799971) Polymorphic Risk Alleles in Patients with Opioid Use Disorder: A Preponderance of Dopaminergic Mechanisms? | GondrΓ©-Lewis MC et al. | β | 2022 | β |
| Future Newborns with Opioid-Induced Neonatal Abstinence Syndrome (NAS) Could Be Assessed with the Genetic Addiction Risk Severity (GARS) Test and Potentially Treated Using Precision Amino-Acid Enkephalinase Inhibition Therapy (KB220) as a Frontline Modality Instead of Potent Opioids. | Ceccanti M et al. | β | 2022 | β |
| Genetic Addiction Risk Severity Assessment Identifies Polymorphic Reward Genes as Antecedents to Reward Deficiency Syndrome (RDS) Hypodopaminergia's Effect on Addictive and Non-Addictive Behaviors in a Nuclear Family. | Dennen CA et al. | β | 2022 | β |
| <i>Ankk1</i> Loss of Function Disrupts Dopaminergic Pathways in Zebrafish. | Leggieri A et al. | β | 2022 | β |
| Olfactory regulation by dopamine and DRD2 receptor in the nose. | Zhou HQ et al. | β | 2022 | β |
| Overcoming reward deficiency syndrome by the induction of "dopamine homeostasis" instead of opioids for addiction: illusion or reality? | Blum K et al. | β | 2022 | β |
| Pharmacogenetics of Addiction Therapy. | Graham DP et al. | β | 2022 | β |
| Precision Behavioral Management (PBM) and Cognitive Control as a Potential Therapeutic and Prophylactic Modality for Reward Deficiency Syndrome (RDS): Is There Enough Evidence? | Madigan MA et al. | β | 2022 | β |
| Researching Mitigation of Alcohol Binge Drinking in Polydrug Abuse: KCNK13 and RASGRF2 Gene(s) Risk Polymorphisms Coupled with Genetic Addiction Risk Severity (GARS) Guiding Precision Pro-Dopamine Regulation. | Blum K et al. | β | 2022 | β |
| Reward Deficiency Syndrome (RDS) Surprisingly Is Evolutionary and Found Everywhere: Is It "Blowin' in the Wind"? | Blum K et al. | β | 2022 | β |
| Should Reward Deficiency Syndrome (RDS) Be Considered an Umbrella Disorder for Mental Illness and Associated Genetic and Epigenetic Induced Dysregulation of Brain Reward Circuitry? | Blum K et al. | β | 2022 | β |
| Statistical Validation of Risk Alleles in Genetic Addiction Risk Severity (GARS) Test: Early Identification of Risk for Alcohol Use Disorder (AUD) in 74,566 Case-Control Subjects. | Blum K et al. | β | 2022 | β |
| The Personality Traits and P300 of Offspring of Parents With Alcohol Dependence Differ Depending on Current Risky Drinking: A Preliminary Case-Control Study. | Qiu Y et al. | β | 2022 | β |
| A comprehensive in silico investigation into the nsSNPs of Drd2 gene predicts significant functional consequences in dopamine signaling and pharmacotherapy. | Lira SS et al. | β | 2021 | β |
| A Novel Precision Approach to Overcome the "Addiction Pandemic" by Incorporating Genetic Addiction Risk Severity (GARS) and Dopamine Homeostasis Restoration. | Blum K et al. | β | 2021 | β |
| A Review of DNA Risk Alleles to Determine Epigenetic Repair of mRNA Expression to Prove Therapeutic Effectiveness in Reward Deficiency Syndrome (RDS): Embracing "Precision Behavioral Management". | Blum K et al. | β | 2021 | β |
| Biochemical Correlates of Video Game Use: From Physiology to Pathology. A Narrative Review. | Carpita B et al. | β | 2021 | β |
| Can eastern wisdom resolve western epidemics? Traditional Chinese medicine therapies and the opioid crisis. | Efferth T et al. | β | 2021 | β |
| Cannabis-Induced Hypodopaminergic Anhedonia and Cognitive Decline in Humans: Embracing Putative Induction of Dopamine Homeostasis. | Blum K et al. | β | 2021 | β |
| Dopamine D2 receptor regulates cortical synaptic pruning in rodents. | Zhang YQ et al. | β | 2021 | β |
| Endorphinergic Enhancement Attenuation of Post-traumatic Stress Disorder (PTSD) <i>via</i> Activation of Neuro-immunological Function in the Face of a Viral Pandemic. | Blum K et al. | β | 2021 | β |
| Exploration of Epigenetic State Hyperdopaminergia (Surfeit) and Genetic Trait Hypodopaminergia (Deficit) During Adolescent Brain Development. | Blum K et al. | β | 2021 | β |
| Opioid and dopamine genes interact to predict precision naltrexone response in alcohol use disorder: Interpretation misfires. | Blum K et al. | β | 2021 | β |
| Reward Deficiency Syndrome (RDS): A Cytoarchitectural Common Neurobiological Trait of All Addictions. | Blum K et al. | β | 2021 | β |
| Translational and Molecular Cytoarchitectural Genetic Guided Therapy to Induce Dopamine Homeostatic Neuro-signaling in Reward Deficiency and Associated Drug and Behavioral Addiction Seeking: A 60 Year Sojourn the Future is Now. | Blum K et al. | β | 2021 | β |
| Ankyrin Repeat and Kinase Domain Containing 1 Gene, and Addiction Vulnerability. | Koeneke A et al. | β | 2020 | β |
| Biotechnical development of genetic addiction risk score (GARS) and selective evidence for inclusion of polymorphic allelic risk in substance use disorder (SUD). | Blum K et al. | β | 2020 | β |
| DSM-5 Maladaptive Personality Domains among Treatment-Seeking Individuals with Alcohol Use Disorder: The Role of Disinhibition and Negative Affectivity. | Cavicchioli M et al. | β | 2020 | β |
| Hypodopaminergia and "Precision Behavioral Management" (PBM): It is a Generational Family Affair. | Fried L et al. | β | 2020 | β |
| In Search of Reward Deficiency Syndrome (RDS)-free Controls: The "Holy Grail" in Genetic Addiction Risk Testing. | Blum K et al. | β | 2020 | β |
| Molecular neuro-biological and systemic health benefits of achieving dopamine homeostasis in the face of a catastrophic pandemic (COVID- 19): A mechanistic exploration. | Downs BW et al. | β | 2020 | β |
| Neurological correlates of brain reward circuitry linked to opioid use disorder (OUD): Do homo sapiens acquire or have a reward deficiency syndrome? | Gold MS et al. | β | 2020 | β |
| Neuropharmacological and Neurogenetic Correlates of Opioid Use Disorder (OUD) As a Function of Ethnicity: Relevance to Precision Addiction Medicine. | Abijo T et al. | β | 2020 | β |
| Polygenic and multi locus heritability of alcoholism: Novel therapeutic targets to overcome psychological deficits. | Blum K et al. | β | 2020 | β |
| Post-Developmental Roles of Notch Signaling in the Nervous System. | Salazar JL et al. | β | 2020 | β |
| Pre-clinical models of reward deficiency syndrome: A behavioral octopus. | GondrΓ©-Lewis MC et al. | β | 2020 | β |
| Transmodulation of Dopaminergic Signaling to Mitigate Hypodopminergia and Pharmaceutical Opioid-Induced Hyperalgesia. | Brewer R et al. | β | 2020 | β |
| Assessment of the Association of D2 Dopamine Receptor Gene and Reported Allele Frequencies With Alcohol Use Disorders: A Systematic Review and Meta-analysis. | Jung Y et al. | β | 2019 | β |
| Association between internet gaming addiction and leukocyte telomere length in Korean male adolescents. | Kim N et al. | β | 2019 | β |
| Axonal degeneration in Parkinson's disease - Basal ganglia circuitry and D2 receptor availability. | Pelzer EA et al. | β | 2019 | β |
| Can We Combat Reward Deficiency Behaviors (RDS) including Substance Use Disorder (SUD) through Genetic Risk Screening coupled with Precision Pro-Dopamine Regulation by Algorithmic matched Polymorphic Allelic Risks. | Blum K et al. | β | 2019 | β |
| Genetic and Environmental Risk Factors for Cannabis Use: Preliminary Results for the Role of Parental Care Perception. | Gerra MC et al. | β | 2019 | β |
| Molecular Imaging of Opioid and Dopamine Systems: Insights Into the Pharmacogenetics of Opioid Use Disorders. | Burns JA et al. | β | 2019 | β |
| Understanding the Scientific Basis of Post-traumatic Stress Disorder (PTSD): Precision Behavioral Management Overrides Stigmatization. | Blum K et al. | β | 2019 | β |
| Evaluation of association of DRD2 TaqIA and -141C InsDel polymorphisms with food intake and anthropometric data in children at the first stages of development. | Feistauer V et al. | β | 2018 | β |
| From genes to treatments: a systematic review of the pharmacogenetics in smoking cessation. | Salloum NC et al. | β | 2018 | β |
| Insurance Companies Fighting the Peer Review Empire without any Validity: the Case for Addiction and Pain Modalities in the face of an American Drug Epidemic. | Blum K et al. | β | 2018 | β |
| Introducing Precision Addiction Management of Reward Deficiency Syndrome, the Construct That Underpins All Addictive Behaviors. | Blum K et al. | β | 2018 | β |
| TAQ1A1 Allele of the DRD2 Gene Region Contribute to Shorter Survival Time in Alcohol Dependent Individuals When Controlling for the Influence of Age and Gender. A Follow-up Study of 18 Years. | Balldin J et al. | β | 2018 | β |
| Taq1A polymorphism and medication effects on inhibitory action control in Parkinson disease. | McDonell KE et al. | β | 2018 | β |
| The Benefits of Genetic Addiction Risk Score (GARS<sup>β’</sup>) Testing in Substance Use Disorder (SUD). | Blum K et al. | β | 2018 | β |
| The benefits of genetic addiction risk score (GARSβ’) and pro-dopamine regulation in combating suicide in the American Indian population. | Blum K et al. | β | 2018 | β |
| Trace Amines and Their Receptors. | Gainetdinov RR et al. | β | 2018 | β |
| Common Neurogenetic Diagnosis and Meso-Limbic Manipulation of Hypodopaminergic Function in Reward Deficiency Syndrome (RDS): Changing the Recovery Landscape. | Blum K et al. | β | 2017 | β |
| Coupling Genetic Addiction Risk Score (GARS) and Pro Dopamine Regulation (KB220) to Combat Substance Use Disorder (SUD). | Blum K et al. | β | 2017 | β |
| "Dopamine homeostasis" requires balanced polypharmacy: Issue with destructive, powerful dopamine agents to combat America's drug epidemic. | Blum K et al. | β | 2017 | β |
| DRD2: Bridging the Genome and Ingestive Behavior. | Sun X et al. | β | 2017 | β |
| Genetic Correlates of Spirituality/Religion and Depression: A Study in Offspring and Grandchildren at High and Low Familial Risk for Depression. | Anderson MR et al. | β | 2017 | β |
| GLOBAL OPIOID EPIDEMIC: DOOMED TO FAIL WITHOUT GENETICALLY BASED PRECISION ADDICTION MEDICINE (PAM<sup>β’</sup>): LESSONS LEARNED FROM AMERICA. | Blum K et al. | β | 2017 | β |
| Polymorphisms in dopaminergic system genes; association with criminal behavior and self-reported aggression in violent prison inmates from Pakistan. | Qadeer MI et al. | β | 2017 | β |
| Pro-Dopamine Regulator - (KB220) to Balance Brain Reward Circuitry in Reward Deficiency Syndrome (RDS). | Blum K et al. | β | 2017 | β |
| Relationship between family history of alcohol addiction, parents' education level, and smartphone problem use scale scores. | Beison A et al. | β | 2017 | β |
| Aberrant neural signatures of decision-making: Pathological gamblers display cortico-striatal hypersensitivity to extreme gambles. | Gelskov SV et al. | β | 2016 | β |
| Dopamine D2 gene expression interacts with environmental enrichment to impact lifespan and behavior. | Thanos PK et al. | β | 2016 | β |
| Fifty Years in the Development of a Glutaminergic-Dopaminergic Optimization Complex (KB220) to Balance Brain Reward Circuitry in Reward Deficiency Syndrome: A Pictorial. | Blum K et al. | β | 2016 | β |
| Genetic variation and dopamine D2 receptor availability: a systematic review and meta-analysis of human in vivo molecular imaging studies. | Gluskin BS et al. | β | 2016 | β |
| Hypothesizing Molecular Genetics of the Holocaust: Were Dopaminergic Genes Involved or Brain Wash? | Blum K et al. | β | 2016 | β |
| Novelty Seeking and Drug Addiction in Humans and Animals: From Behavior to Molecules. | Wingo T et al. | β | 2016 | β |
| Targeted exome sequencing for the identification of a protective variant against Internet gaming disorder at rs2229910 of neurotrophic tyrosine kinase receptor, type 3 (NTRK3): A pilot study. | Kim JY et al. | β | 2016 | β |
| The Addiction-Related Gene Ankk1 is Oppositely Regulated by D1R- and D2R-Like Dopamine Receptors. | Ponce G et al. | β | 2016 | β |
| THE BENEFITS OF CUSTOMIZED DNA DIRECTED NUTRITION TO BALANCE THE BRAIN REWARD CIRCUITRY AND REDUCE ADDICTIVE BEHAVIORS. | Blum K et al. | β | 2016 | β |
| Addiction pharmacogenetics: a systematic review of the genetic variation of the dopaminergic system. | Patriquin MA et al. | β | 2015 | β |
| A Shared Molecular and Genetic Basis for Food and Drug Addiction: Overcoming Hypodopaminergic Trait/State by Incorporating Dopamine Agonistic Therapy in Psychiatry. | Gold MS et al. | β | 2015 | β |
| Association study of the SLC6A3 VNTR (DAT) and DRD2/ANKK1 Taq1A polymorphisms with alcohol dependence in a population from northeastern Brazil. | Vasconcelos AC et al. | β | 2015 | β |
| Candidate gene-environment interaction research: reflections and recommendations. | Dick DM et al. | β | 2015 | β |
| Can Genetic Testing Provide Information to Develop Customized Nutrigenomic Solutions for Reward Deficiency Syndrome? | Blum K et al. | β | 2015 | β |
| Clinically Combating Reward Deficiency Syndrome (RDS) with Dopamine Agonist Therapy as a Paradigm Shift: Dopamine for Dinner? | Blum K et al. | β | 2015 | β |
| Clinically relevant genetic biomarkers from the brain in alcoholism with representation on high resolution chromosome ideograms. | Manzardo AM et al. | β | 2015 | β |
| Common single nucleotide variants underlying drug addiction: more than a decade of research. | BΓΌhler KM et al. | β | 2015 | β |
| Coupling Neurogenetics (GARSβ’) and a Nutrigenomic Based Dopaminergic Agonist to Treat Reward Deficiency Syndrome (RDS): Targeting Polymorphic Reward Genes for Carbohydrate Addiction Algorithms. | Blum K et al. | β | 2015 | β |
| Hypersexuality Addiction and Withdrawal: Phenomenology, Neurogenetics and Epigenetics. | Blum K et al. | β | 2015 | β |
| Hypersexuality Addiction and Withdrawal: Phenomenology, Neurogenetics and Epigenetics. | Blum K et al. | β | 2015 | β |
| Moderating Effects of Genetic Polymorphisms on Improvements in Cognitive Impairment in Breast Cancer Survivors Participating in a 6-Week Mindfulness-Based Stress Reduction Program. | Lengacher CA et al. | β | 2015 | β |
| Molecular Genetic Testing in Pain and Addiction: Facts, Fiction and Clinical Utility. | Blum K et al. | β | 2015 | β |
| Molecular Genetic Testing in Reward Deficiency Syndrome (RDS): Facts and Fiction. | Blum K et al. | β | 2015 | β |
| Neural correlates of taste and pleasantness evaluation in the metabolic syndrome. | Green E et al. | β | 2015 | β |
| Neurogenetics and gene therapy for reward deficiency syndrome: are we going to the Promised Land? | Blum K et al. | β | 2015 | β |
| Neuroscience of Internet Pornography Addiction: A Review and Update. | Love T et al. | β | 2015 | β |
| NIDA-Drug Addiction Treatment Outcome Study (DATOS) Relapse as a Function of Spirituality/Religiosity. | Schoenthaler SJ et al. | β | 2015 | β |
| Regulation of ethanol intake under chronic mild stress: roles of dopamine receptors and transporters. | Delis F et al. | β | 2015 | β |
| The Molecular Neurobiology of Twelve Steps Program & Fellowship: Connecting the Dots for Recovery. | Blum K et al. | β | 2015 | β |
| Updated findings of the association and functional studies of DRD2/ANKK1 variants with addictions. | Ma Y et al. | β | 2015 | β |
| Alcohol abuse and HIV infection: role of DRD2. | Agudelo M et al. | β | 2014 | β |
| Association of CREB1 gene polymorphism with drug seeking behaviour in eastern Indian addicts. | Pal A et al. | β | 2014 | β |
| Association of dopamine receptor D2 TaqI A polymorphism and cannabis use disorder in Lagos, Nigeria. | Adedeji OH et al. | β | 2014 | β |
| A variant in ANKK1 modulates acute subjective effects of cocaine: a preliminary study. | Spellicy CJ et al. | β | 2014 | β |
| Differential role of D1 and D2 receptors in the perifornical lateral hypothalamus in controlling ethanol drinking and food intake: possible interaction with local orexin neurons. | Chen YW et al. | β | 2014 | β |
| Dopamine and glucose, obesity, and reward deficiency syndrome. | Blum K et al. | β | 2014 | β |
| Genetic Addiction Risk Score (GARS): molecular neurogenetic evidence for predisposition to Reward Deficiency Syndrome (RDS). | Blum K et al. | β | 2014 | β |
| Genetics of alcohol dependence: a review of clinical studies. | Samochowiec J et al. | β | 2014 | β |
| Hatching the behavioral addiction egg: Reward Deficiency Solution System (RDSS)β’ as a function of dopaminergic neurogenetics and brain functional connectivity linking all addictions under a common rubric. | Blum K et al. | β | 2014 | β |
| Hypothesizing Darkness Induced Alcohol Intake Linked to Dopaminergic Regulation of Brain Function. | Blum K et al. | β | 2014 | β |
| Hypothesizing dopaminergic genetic antecedents in schizophrenia and substance seeking behavior. | Blum K et al. | β | 2014 | β |
| Low dopamine function in attention deficit/hyperactivity disorder: should genotyping signify early diagnosis in children? | Gold MS et al. | β | 2014 | β |
| Optogenetic and chemogenetic insights into the food addiction hypothesis. | Krashes MJ et al. | β | 2014 | β |
| Pharmacogenetics of addiction therapy. | Nielsen DA et al. | β | 2014 | β |
| Polymorphisms in genes encoding dopamine signalling pathway and risk of alcohol dependence: a systematic review. | Bhaskar LV et al. | β | 2014 | β |
| Practitioner review: A critical perspective on gene-environment interaction models--what impact should they have on clinical perceptions and practice? | MunafΓ² MR et al. | β | 2014 | β |
| The dopamine system and alcohol dependence. | Ma H et al. | β | 2014 | β |
| Variation of types of alcoholism: review and subtypes identified in Han Chinese. | Lee SY et al. | β | 2014 | β |
| A large-scale meta-analysis of the association between the ANKK1/DRD2 Taq1A polymorphism and alcohol dependence. | Wang F et al. | β | 2013 | β |
| ANKK1 and DRD2 pharmacogenetics of disulfiram treatment for cocaine abuse. | Spellicy CJ et al. | β | 2013 | β |
| Association between DRD2, 5-HTTLPR, and ALDH2 genes and specific personality traits in alcohol- and opiate-dependent patients. | Wang TY et al. | β | 2013 | β |
| Association of dopamine D2 receptor and leptin receptor genes with clinically severe obesity. | Carpenter CL et al. | β | 2013 | β |
| Association of dopamine receptor gene polymorphism and psychological personality traits in liability for opioid addiction. | MehiΔ-Basara N et al. | β | 2013 | β |
| Association study of DRD2 and MAOA genes with subtyped alcoholism comorbid with bipolar disorder in Han Chinese. | Hu MC et al. | β | 2013 | β |
| Declinol, a Complex Containing Kudzu, Bitter Herbs (Gentian, Tangerine Peel) and Bupleurum, Significantly Reduced Alcohol Use Disorders Identification Test (AUDIT) Scores in Moderate to Heavy Drinkers: A Pilot Study. | Kushner S et al. | β | 2013 | β |
| Dopamine Genetics and Function in Food and Substance Abuse. | Blum K et al. | β | 2013 | β |
| DRD2 and ANKK1 gene polymorphisms and alcohol dependence: a case-control study among a Mendelian population of East Asian ancestry. | Suraj Singh H et al. | β | 2013 | β |
| Fronto-striatal dysregulation in drug addiction and pathological gambling: Consistent inconsistencies? | Limbrick-Oldfield EH et al. | β | 2013 | β |
| Have We Hatched the Addiction Egg: Reward Deficiency Syndrome Solution Systemβ’ | Downs B et al. | β | 2013 | β |
| Multivariate analysis of dopaminergic gene variants as risk factors of heroin dependence. | Vereczkei A et al. | β | 2013 | β |
| Peter Riederer "70th birthday" neurobiological foundations of modern addiction treatment. | Jacob C | β | 2013 | β |
| Polymorphisms of genes in neurotransmitter systems were associated with alcohol use disorders in a Tibetan population. | Xu Y et al. | β | 2013 | β |
| Salsolinol modulation of dopamine neurons. | Xie G et al. | β | 2013 | β |
| The association between DRD2/ANKK1 and genetically informed measures of alcohol use and problems. | Meyers JL et al. | β | 2013 | β |
| Are Internet use and video-game-playing addictive behaviors? Biological, clinical and public health implications for youths and adults. | Yau YH et al. | β | 2012 | β |
| Bridging Animal and Human Models: Translating From (and to) Animal Genetics. | Barkley-Levenson AM et al. | β | 2012 | β |
| Convergence of genome-wide association and candidate gene studies for alcoholism. | Olfson E et al. | β | 2012 | β |
| Custom genotyping for substance addiction susceptibility genes in Jordanians of Arab descent. | Al-Eitan LN et al. | β | 2012 | β |
| DRD2/ANKK1 TaqIA and SLC6A3 VNTR polymorphisms in alcohol dependence: association and gene-gene interaction study in a population of Central Italy. | Mignini F et al. | β | 2012 | β |
| DRD2 C957T and TaqIA genotyping reveals gender effects and unique low-risk and high-risk genotypes in alcohol dependence. | Swagell CD et al. | β | 2012 | β |
| Influence of DRD2 and ANKK1 polymorphisms on the manifestation of withdrawal syndrome symptoms in alcohol addiction. | Grzywacz A et al. | β | 2012 | β |
| Interaction between ALDH2*1*1 and DRD2/ANKK1 TaqI A1A1 genes may be associated with antisocial personality disorder not co-morbid with alcoholism. | Lu RB et al. | β | 2012 | β |
| Intergenerational influences on early alcohol use: independence from the problem behavior pathway. | Kerr DC et al. | β | 2012 | β |
| Neurogenetic Impairments of Brain Reward Circuitry Links to Reward Deficiency Syndrome (RDS): Potential Nutrigenomic Induced Dopaminergic Activation. | Blum K et al. | β | 2012 | β |
| Neuropsychiatric Genetics of Happiness, Friendships, and Politics: Hypothesizing Homophily ("Birds of a Feather Flock Together") as a Function of Reward Gene Polymorphisms. | Blum K et al. | β | 2012 | β |
| Salsolinol facilitates glutamatergic transmission to dopamine neurons in the posterior ventral tegmental area of rats. | Xie G et al. | β | 2012 | β |
| Sex, drugs, and rock 'n' roll: hypothesizing common mesolimbic activation as a function of reward gene polymorphisms. | Blum K et al. | β | 2012 | β |
| The addictive brain: all roads lead to dopamine. | Blum K et al. | β | 2012 | β |
| The aldehyde dehydrogenase 2 gene is associated with heroin dependence. | Wang TY et al. | β | 2012 | β |
| Addiction and brain reward and antireward pathways. | Gardner EL | β | 2011 | β |
| A Nested Allele-Specific Multiplex Polymerase Chain Reaction Method for the Detection of DRD2 Polymorphisms. | Zahari Z et al. | β | 2011 | β |
| Generational association studies of dopaminergic genes in reward deficiency syndrome (RDS) subjects: selecting appropriate phenotypes for reward dependence behaviors. | Blum K et al. | β | 2011 | β |
| Neuro-chemical activation of brain reward meso-limbic circuitry is associated with relapse prevention and drug hunger: a hypothesis. | Blum K et al. | β | 2011 | β |
| Neurogenetics and clinical evidence for the putative activation of the brain reward circuitry by a neuroadaptagen: proposing an addiction candidate gene panel map. | Chen TJ et al. | β | 2011 | β |
| Neuro-Genetics of Reward Deficiency Syndrome (RDS) as the Root Cause of "Addiction Transfer": A New Phenomenon Common after Bariatric Surgery. | Blum K et al. | β | 2011 | β |
| PharmGKB summary: dopamine receptor D2. | Mi H et al. | β | 2011 | β |
| Potential programming of dopaminergic circuits by early life stress. | Rodrigues AJ et al. | β | 2011 | β |
| Reduced nucleus accumbens and caudate nucleus activation to a pleasant taste is associated with obesity in older adults. | Green E et al. | β | 2011 | β |
| The ANKK1 protein associated with addictions has nuclear and cytoplasmic localization and shows a differential response of Ala239Thr to apomorphine. | Garrido E et al. | β | 2011 | β |
| The association between the SLC6A3 VNTR 9-repeat allele and alcoholism-a meta-analysis. | Du Y et al. | β | 2011 | β |
| Acute intravenous synaptamine complex variant KB220β’ "normalizes" neurological dysregulation in patients during protracted abstinence from alcohol and opiates as observed using quantitative electroencephalographic and genetic analysis for reward polymorphisms: part 1, pilot study with 2 case reports. | Miller DK et al. | β | 2010 | β |
| Alcoholism and alternative splicing of candidate genes. | Sasabe T et al. | β | 2010 | β |
| An association analysis of circadian genes in anxiety disorders. | SipilΓ€ T et al. | β | 2010 | β |
| Cellular and mitochondrial effects of alcohol consumption. | Manzo-Avalos S et al. | β | 2010 | β |
| Complexity and accountability: the witches' brew of psychiatric genetics. | Arribas-Ayllon M et al. | β | 2010 | β |
| Differential patterns of alcohol consumption and dopamine-2 receptor binding in Wistar-Kyoto and Wistar rats. | Morganstern I et al. | β | 2010 | β |
| Dopamine D2 receptor genotype is associated with increased mortality at a 10-year follow-up of alcohol-dependent individuals. | Berggren U et al. | β | 2010 | β |
| Dopamine D2 receptor polymorphisms and susceptibility to alcohol dependence in Indian males: a preliminary study. | Prasad P et al. | β | 2010 | β |
| Epigenetics and biomarkers in the staging of neuropsychiatric disorders. | Archer T et al. | β | 2010 | β |
| Genetic polymorphisms in folate and alcohol metabolism and breast cancer risk: a case-control study in Thai women. | Sangrajrang S et al. | β | 2010 | β |
| Imaging the effects of genetic polymorphisms on radioligand binding in the living human brain: A review on genetic neuroreceptor imaging of monoaminergic systems in psychiatry. | Willeit M et al. | β | 2010 | β |
| Influence of DRD2 and ANKK1 genotypes on apomorphine-induced growth hormone (GH) response in alcohol-dependent patients. | Lucht M et al. | β | 2010 | β |
| Long-term effects of chronic khat use: impaired inhibitory control. | Colzato LS et al. | β | 2010 | β |
| Person-environment interaction in the prediction of alcohol abuse and alcohol dependence in adulthood. | Hill KG et al. | β | 2010 | β |
| Pharmacogenetics of drug dependence: role of gene variations in susceptibility and treatment. | Khokhar JY et al. | β | 2010 | β |
| Population-based case-control study of DRD2 gene polymorphisms and alcoholism. | Bhaskar LV et al. | β | 2010 | β |
| The ANKK1 gene associated with addictions is expressed in astroglial cells and upregulated by apomorphine. | Hoenicka J et al. | β | 2010 | β |
| The D2 dopamine receptor gene and nicotine dependence among bladder cancer patients and controls. | Clague J et al. | β | 2010 | β |
| The D2 dopamine receptor gene variant C957T affects human fear conditioning and aversive priming. | Huertas E et al. | β | 2010 | β |
| Waterpipe Smoking And The DRD2/ANKK1 Genotype. | Radwan GN et al. | β | 2010 | β |
| Association of the DRD2 gene Taq1A polymorphism and smoking behavior: a meta-analysis and new data. | MunafΓ² MR et al. | β | 2009 | β |
| Associations of the DRD2 TaqIA polymorphism with impulsivity and substance use: preliminary results from a clinical sample of adolescents. | Esposito-Smythers C et al. | β | 2009 | β |
| C957T polymorphism of dopamine D2 receptor gene affects striatal DRD2 in vivo availability by changing the receptor affinity. | Hirvonen MM et al. | β | 2009 | β |
| C957T polymorphism of the human dopamine D2 receptor gene predicts extrastriatal dopamine receptor availability in vivo. | Hirvonen MM et al. | β | 2009 | β |
| Candidate gene studies of ADHD: a meta-analytic review. | Gizer IR et al. | β | 2009 | β |
| Dopamine dysregulation syndrome: an overview of its epidemiology, mechanisms and management. | O'Sullivan SS et al. | β | 2009 | β |
| Effect of the TaqIA polymorphism on ethanol response in the brain. | London ED et al. | β | 2009 | β |
| Ethanol facilitates glutamatergic transmission to dopamine neurons in the ventral tegmental area. | Xiao C et al. | β | 2009 | β |
| Gender effect on association between DRD2 polymorphism and substance dependence in a Spanish sample. | LΓ³pez-CastromΓ‘n J et al. | β | 2009 | β |
| Gene-environment interactions across development: Exploring DRD2 genotype and prenatal smoking effects on self-regulation. | Wiebe SA et al. | β | 2009 | β |
| [Genetic factors of alcohol-dependence]. | Pinto E et al. | β | 2009 | β |
| Influences of polymorphic variants of DRD2 and SLC6A3 genes, and their combinations on smoking in Polish population. | Sieminska A et al. | β | 2009 | β |
| Neurogenetics of dopaminergic receptor supersensitivity in activation of brain reward circuitry and relapse: proposing "deprivation-amplification relapse therapy" (DART). | Blum K et al. | β | 2009 | β |
| Potential association of DRD2 and DAT1 genetic variation with heroin dependence. | Hou QF et al. | β | 2009 | β |
| Prediction of deleterious non-synonymous single nucleotide polymorphisms of genes related to ethanol-induced toxicity. | Wang LL et al. | β | 2009 | β |
| Recreational cocaine polydrug use impairs cognitive flexibility but not working memory. | Colzato LS et al. | β | 2009 | β |
| The ANKK1 kinase gene and psychiatric disorders. | Ponce G et al. | β | 2009 | β |
| Unraveling the molecular mechanisms of alcohol dependence. | Kalsi G et al. | β | 2009 | β |
| Approach to the genetics of alcoholism: a review based on pathophysiology. | KΓΆhnke MD | β | 2008 | β |
| Attention-deficit-hyperactivity disorder and reward deficiency syndrome. | Blum K et al. | β | 2008 | β |
| Cloninger's typology and treatment outcome in alcohol-dependent subjects during pharmacotherapy with naltrexone. | Kiefer F et al. | β | 2008 | β |
| Dopaminergic mutations: within-family association and linkage in multiplex alcohol dependence families. | Hill SY et al. | β | 2008 | β |
| DRD2 and ANKK1 genotype in alcohol-dependent patients with psychopathic traits: association and interaction study. | Ponce G et al. | β | 2008 | β |
| Drd2 expression in the high alcohol-preferring and low alcohol-preferring mice. | Bice PJ et al. | β | 2008 | β |
| EEG biofeedback as a treatment for substance use disorders: review, rating of efficacy, and recommendations for further research. | Sokhadze TM et al. | β | 2008 | β |
| Enhanced dopamine D2 receptor function in hypothalamus and corpus striatum: their role in liver, plasma and in vitro hepatocyte ALDH regulation in ethanol treated rats. | Akash KG et al. | β | 2008 | β |
| Identification of Quantitative Trait Loci and candidate genes influencing ethanol sensitivity in honey bees. | Ammons AD et al. | β | 2008 | β |
| Impulsivity as a vulnerability marker for substance-use disorders: review of findings from high-risk research, problem gamblers and genetic association studies. | Verdejo-GarcΓa A et al. | β | 2008 | β |
| LG839: anti-obesity effects and polymorphic gene correlates of reward deficiency syndrome. | Blum K et al. | β | 2008 | β |
| Meta-analysis of the association of the Taq1A polymorphism with the risk of alcohol dependency: a HuGE gene-disease association review. | Smith L et al. | β | 2008 | β |
| Nanomolar propofol stimulates glutamate transmission to dopamine neurons: a possible mechanism of abuse potential? | Li KY et al. | β | 2008 | β |
| The A1 allele of the D2 dopamine receptor gene region, alcohol expectancies and drinking refusal self-efficacy are associated with alcohol dependence severity. | Connor JP et al. | β | 2008 | β |
| The association between DRD2/ANKK1, 5-HTTLPR gene, and specific personality trait on antisocial alcoholism among Han Chinese in Taiwan. | Wu CY et al. | β | 2008 | β |
| The End of Behavioral Genetics? | McGue M | β | 2008 | β |
| The genetics of alcohol and other drug dependence. | Dick DM et al. | β | 2008 | β |
| Association in alcoholic patients between psychopathic traits and the additive effect of allelic forms of the CNR1 and FAAH endocannabinoid genes, and the 3' region of the DRD2 gene. | Hoenicka J et al. | β | 2007 | β |
| Bupropion efficacy for smoking cessation is influenced by the DRD2 Taq1A polymorphism: analysis of pooled data from two clinical trials. | David SP et al. | β | 2007 | β |
| Decreased dopamine D(2) receptor function in cerebral cortex and brain stem: their role in hepatic ALDH regulation in ethanol treated rats. | George AK et al. | β | 2007 | β |
| Dopamine genes and reward dependence in adolescents with excessive internet video game play. | Han DH et al. | β | 2007 | β |
| Family-based association analyses of alcohol dependence phenotypes across DRD2 and neighboring gene ANKK1. | Dick DM et al. | β | 2007 | β |
| Gene-lifecourse interaction for alcohol consumption in adolescence and young adulthood: five monoamine genes. | Guo G et al. | β | 2007 | β |
| Gene \Narcotic Attenuation Program attenuates substance use disorder, a clinical subtype of reward deficiency syndrome. | Chen TJ et al. | β | 2007 | β |
| Genetic and environmental factors in complex neurodevelopmental disorders. | van Loo KM et al. | β | 2007 | β |
| Genotrim, a DNA-customized nutrigenomic product, targets genetic factors of obesity: hypothesizing a dopamine-glucose correlation demonstrating reward deficiency syndrome (RDS). | Blum K et al. | β | 2007 | β |
| Manipulation of catechol-O-methyl-transferase (COMT) activity to influence the attenuation of substance seeking behavior, a subtype of Reward Deficiency Syndrome (RDS), is dependent upon gene polymorphisms: a hypothesis. | Blum K et al. | β | 2007 | β |
| Monoamine oxidase-A polymorphisms might modify the association between the dopamine D2 receptor gene and alcohol dependence. | Huang SY et al. | β | 2007 | β |
| Test of association between TaqIA A1 allele and alcohol use disorder phenotypes in a sample of adolescent patients with serious substance and behavioral problems. | Sakai JT et al. | β | 2007 | β |
| Association between the DRD2 A1 allele and response to methadone and buprenorphine maintenance treatments. | Barratt DT et al. | β | 2006 | β |
| Case-control studies in the genomic era: a clinician's guide. | Healy DG | β | 2006 | β |
| Impulsivity and sustained attention in pathological gamblers: influence of childhood ADHD history. | Rodriguez-Jimenez R et al. | β | 2006 | β |
| Neurotoxins and neurotoxicity mechanisms. An overview. | Segura-Aguilar J et al. | β | 2006 | β |
| The genetics of alcohol dependence. | Dick DM et al. | β | 2006 | β |
| The genetics of attention deficit hyperactivity disorder. | Waldman ID et al. | β | 2006 | β |
| The H-Wave small muscle fiber stimulator, a nonpharmacologic alternative for the treatment of chronic soft-tissue injury and neuropathic pain: an extended population observational study. | Blum K et al. | β | 2006 | β |
| The next challenge for psychiatric genetics: characterizing the risk associated with identified genes. | Dick DM et al. | β | 2006 | β |
| The TaqIA polymorphism linked to the DRD2 gene is related to lower attention and less inhibitory control in alcoholic patients. | RodrΓguez-JimΓ©nez R et al. | β | 2006 | β |
| Association between the DRD2 A1 allele and opium addiction in the Iranian population. | Shahmoradgoli Najafabadi M et al. | β | 2005 | β |
| Association study of dopamine D2 and D3 receptor gene polymorphisms with cocaine dependence. | Messas G et al. | β | 2005 | β |
| Clinical predictors of response to naltrexone in alcoholic patients: who benefits most from treatment with naltrexone? | Rubio G et al. | β | 2005 | β |
| [DNA polymorphisms and alcoholism]. | Pastor I et al. | β | 2005 | β |
| Ebrii gignunt ebrios--One drunkard begets another: the genetics of alcohol dependence. | Ball D | β | 2005 | β |
| Evolution of the DRD2 gene haplotype and its association with alcoholism in Mexican Americans. | Luo HR et al. | β | 2005 | β |
| Levels and circadian rhythmicity of plasma ACTH, cortisol, and beta-endorphin as a function of family history of alcoholism. | Gianoulakis C et al. | β | 2005 | β |
| Neurobiochemical and clinical aspects of craving in alcohol addiction: a review. | Addolorato G et al. | β | 2005 | β |
| Neurogenetic interactions and aberrant behavioral co-morbidity of attention deficit hyperactivity disorder (ADHD): dispelling myths. | Comings DE et al. | β | 2005 | β |
| Nicotine addiction through a neurogenomic prism: ethics, public health, and smoking. | Caron L et al. | β | 2005 | β |
| The A1 allele of the human D2 dopamine receptor gene is associated with increased activity of striatal L-amino acid decarboxylase in healthy subjects. | Laakso A et al. | β | 2005 | β |
| The association between the DRD2 TaqI A polymorphism and smoking cessation in response to acupuncture in Koreans. | Park HJ et al. | β | 2005 | β |
| Advances in molecular genetics and the prevention and treatment of substance misuse: Implications of association studies of the A1 allele of the D2 dopamine receptor gene. | Young RM et al. | β | 2004 | β |
| Alcohol-related expectancies are associated with the D2 dopamine receptor and GABAA receptor beta3 subunit genes. | Young RM et al. | β | 2004 | β |
| An assessment of transmission disequilibrium between quantitative measures of childhood problem behaviors and DRD2/Taql and DRD4/48bp-repeat polymorphisms. | Marino C et al. | β | 2004 | β |
| Dopamine and alcoholism: neurobiological basis of ethanol abuse. | Tupala E et al. | β | 2004 | β |
| Gene-environment interactions in mental disorders. | Tsuang MT et al. | β | 2004 | β |
| Gene-environment interplay in alcoholism and other substance abuse disorders: expressions of heritability and factors influencing vulnerability. | Palomo T et al. | β | 2004 | β |
| Genetic approaches to alcohol dependence. | Ball D | β | 2004 | β |
| IDRD2 TaqIA polymorphism is associated with urinary homovanillic acid levels in a sample of Spanish male alcoholic patients. | Ponce G et al. | β | 2004 | β |
| Pharmacogenetic studies of alcohol self-administration and withdrawal. | Crabbe JC et al. | β | 2004 | β |
| Polymorphisms of the dopamine D2 receptor, serotonin transporter, and GABA(A) receptor beta(3) subunit genes and alcoholism in Mexican-Americans. | Konishi T et al. | β | 2004 | β |
| Population stratification in the candidate gene study: fatal threat or red herring? | Hutchison KE et al. | β | 2004 | β |
| [The role of genetics in alcohol dependence]. | Messas GP et al. | β | 2004 | β |
| Approaches to identify genes for complex human diseases: lessons from Mendelian disorders. | Dean M | β | 2003 | β |
| Association of seven polymorphisms of the D2 dopamine receptor gene with brain receptor-binding characteristics. | Ritchie T et al. | β | 2003 | β |
| Candidate genes for alcohol dependence: a review of genetic evidence from human studies. | Dick DM et al. | β | 2003 | β |
| Dopamine D2 receptor binding, Drd2 expression and the number of dopamine neurons in the BXD recombinant inbred series: genetic relationships to alcohol and other drug associated phenotypes. | Hitzemann R et al. | β | 2003 | β |
| Dopamine D2 receptors and transporters in type 1 and 2 alcoholics measured with human whole hemisphere autoradiography. | Tupala E et al. | β | 2003 | β |
| Gender-specific molecular heterosis and association studies: dopamine D2 receptor gene and smoking. | Lee HS | β | 2003 | β |
| Genetic influences on smoking behavior and nicotine dependence: a review. | Yoshimasu K et al. | β | 2003 | β |
| Nonreplication in genetic association studies of obesity and diabetes research. | Redden DT et al. | β | 2003 | β |
| Psychopathology in the postgenomic era. | Plomin R et al. | β | 2003 | β |
| Spouses and unrelated friends of probands as controls for stroke genetics studies. | Worrall BB et al. | β | 2003 | β |
| The A1 allele of the DRD2 gene (TaqI A polymorphisms) is associated with antisocial personality in a sample of alcohol-dependent patients. | Ponce G et al. | β | 2003 | β |
| Toward a molecular architecture of personality. | Reif A et al. | β | 2003 | β |
| Association between smoking habits and dopamine receptor D2 taqI A A2 allele in Japanese males: a confirmatory study. | Hamajima N et al. | β | 2002 | β |
| D(2) dopamine receptor (DRD2) polymorphism is associated with severity of alcohol dependence. | Connor JP et al. | β | 2002 | β |
| Effects of alcohol detoxification on dopamine D2 receptors in alcoholics: a preliminary study. | Volkow ND et al. | β | 2002 | β |
| Effects of the interaction between genotype and environment. Research into the genetic epidemiology of alcohol dependence. | Heath AC et al. | β | 2002 | β |
| Experimental genetic approaches to addiction. | Laakso A et al. | β | 2002 | β |
| From Zebrafish to human: modular medical models. | Shin JT et al. | β | 2002 | β |
| Gender-specific molecular heterosis of dopamine D2 receptor gene (DRD2) for smoking in schizophrenia. | Lee HS et al. | β | 2002 | β |
| Male limited association of the dopamine receptor D2 gene TaqI a polymorphism and alcohol dependence. | Limosin F et al. | β | 2002 | β |
| No association between the dopamine D3 receptor gene and Korean alcohol dependence. | Lee MS et al. | β | 2002 | β |
| Potentially functional polymorphism in the promoter region of prodynorphin gene may be associated with protection against cocaine dependence or abuse. | Chen AC et al. | β | 2002 | β |
| Prevention and risk of adolescent substance abuse. The role of adolescents, families, and communities. | Kodjo CM et al. | β | 2002 | β |
| The heritability of alcohol abuse and dependence: a meta-analysis of behavior genetic research. | Walters GD | β | 2002 | β |
| The prevention of gambling problems in youth: a conceptual framework. | Dickson LM et al. | β | 2002 | β |
| Clinical and molecular genetics of ADHD and Tourette syndrome. Two related polygenic disorders. | Comings DE | β | 2001 | β |
| Dopamine D2 receptor gene (DRD2) is associated with alcoholism with conduct disorder. | Lu RB et al. | β | 2001 | β |
| Finding paradigms for the future of alcoholism research: an interdisciplinary perspective. | Meyer RE | β | 2001 | β |
| Genetic determinants of alcohol addiction and metabolism: a survey in Italy. | Pastorelli R et al. | β | 2001 | β |
| Genetic polymorphisms of the promoter region of dopamine D2 receptor and dopamine transporter genes and alcoholism among four aboriginal groups and Han Chinese in Taiwan. | Chen WJ et al. | β | 2001 | β |
| Genetic variations and polymorphisms of G protein-coupled receptors: functional and therapeutic implications. | Rana BK et al. | β | 2001 | β |
| Imaging neurochemical endophenotypes: promises and pitfalls. | Martinez D et al. | β | 2001 | β |
| Influence of the endogenous opioid system on high alcohol consumption and genetic predisposition to alcoholism. | Gianoulakis C | β | 2001 | β |
| No association between the dopamine d2 receptor taqi a1 allele and earlier age of onset of alcohol dependence according to different specified criteria. | Anghelescu I et al. | β | 2001 | β |
| Overexpression of dopamine D2 receptors reduces alcohol self-administration. | Thanos PK et al. | β | 2001 | β |
| P300 event-related potential amplitude as an endophenotype of alcoholism--evidence from the collaborative study on the genetics of alcoholism. | Hesselbrock V et al. | β | 2001 | β |
| Polymorphisms at the DRD2 locus in early-onset alcohol dependence in the Indian population. | Shaikh KJ et al. | β | 2001 | β |
| Population admixture: detection by Hardy-Weinberg test and its quantitative effects on linkage-disequilibrium methods for localizing genes underlying complex traits. | Deng HW et al. | β | 2001 | β |
| Alcoholism susceptibility loci: confirmation studies in a replicate sample and further mapping. | Foroud T et al. | β | 2000 | β |
| An allelic variation in the human prodynorphin gene promoter alters stimulus-induced expression. | Zimprich A et al. | β | 2000 | β |
| A note on a conditional-likelihood approach for family-based association studies of candidate genes. | Hsu L et al. | β | 2000 | β |
| Ascertainment of families for a linkage study of alcoholism. | Cook CC et al. | β | 2000 | β |
| Association of D2 dopamine receptor and alcohol dehydrogenase 2 genes with Polynesian alcoholics. | AmadΓ©o S et al. | β | 2000 | β |
| Biological phenotypes associated with individuals at high risk for developing alcohol-related disorders: Part 1. | Hill SY | β | 2000 | β |
| DNA. | Plomin R et al. | β | 2000 | β |
| Family-based study of DRD2 alleles in alcohol and drug dependence. | Blomqvist O et al. | β | 2000 | β |
| Functional variant in the DRD2 receptor promoter region and subtypes of alcoholism. | Parsian A et al. | β | 2000 | β |
| Genetics of alcohol withdrawal. | Schmidt LG et al. | β | 2000 | β |
| Genetic studies of substance abuse. | Vanyukov MM et al. | β | 2000 | β |
| Genome polymorphism and alcoholism. | Thome J et al. | β | 2000 | β |
| Haplotypes at the DRD2 locus and severe alcoholism. | Noble EP et al. | β | 2000 | β |
| Pharmacogenetics. Promise and potential in child and adolescent psychiatry. | Anderson GM et al. | β | 2000 | β |
| Pharmacogenomics and addiction to opiates. | Lichtermann D et al. | β | 2000 | β |
| Place, social exchange and health: proposed sociological framework. | Siegrist J | β | 2000 | β |
| Polymorphisms in dopamine receptors: what do they tell us? | Wong AH et al. | β | 2000 | β |
| The dopamine D2 receptor (DRD2) gene-a genetic risk factor in heavy smoking? | Batra A et al. | β | 2000 | β |
| The DRD2 gene and the risk for alcohol dependence in bipolar patients. | Gorwood P et al. | β | 2000 | β |
| The DRD2 gene in psychiatric and neurological disorders and its phenotypes. | Noble EP | β | 2000 | β |
| The TaqI A1 allele of the dopamine D2 receptor gene and alcoholism in Brazil: association and interaction with stress and harm avoidance on severity prediction. | Bau CH et al. | β | 2000 | β |
| Benefits and pitfalls encountered in psychiatric genetic association studies. | Malhotra AK et al. | β | 1999 | β |
| Effect of bromocriptine on acute ethanol tolerance in UChB rats. | Tampier L et al. | β | 1999 | β |
| Effects of L-type voltage-sensitive calcium channel modulators on the discriminative stimulus effects of ethanol in rats. | Green KL et al. | β | 1999 | β |
| Genetic studies of alcoholism and substance dependence. | Reich T et al. | β | 1999 | β |
| Genetic susceptibility to neurodevelopmental disorders. | Ryan SG | β | 1999 | β |
| Human dopamine D4 receptor allele genotyping by ultrathin agarose gel electrophoresis with To-Pro-3 complexation. | Szoke M et al. | β | 1999 | β |
| Individual risk factors for adolescent substance use. | Swadi H | β | 1999 | β |
| Joint multipoint linkage analysis of multivariate qualitative and quantitative traits. II. Alcoholism and event-related potentials. | Williams JT et al. | β | 1999 | β |
| Lack of an allelic association between polymorphisms of the dopamine D2 receptor gene and alcohol dependence in the German population. | Sander T et al. | β | 1999 | β |
| Linkage studies of D2 and D4 receptor genes and alcoholism. | Hill SY et al. | β | 1999 | β |
| No association between D2 dopamine receptor (DRD2) alleles or haplotypes and cocaine dependence or severity of cocaine dependence in European- and African-Americans. | Gelernter J et al. | β | 1999 | β |
| No association between D2 dopamine receptor (DRD2) "A" system alleles, or DRD2 haplotypes, and posttraumatic stress disorder. | Gelernter J et al. | β | 1999 | β |
| Polymorphism of dopamine D2 and D4 receptor genes and Slavic-surnamed alcoholic patients. | Ovchinnikov IV et al. | β | 1999 | β |
| A family-based analysis of the association of the dopamine D2 receptor (DRD2) with alcoholism. | Edenberg HJ et al. | β | 1998 | β |
| A functionally deficient DRD2 variant [Ser311Cys] is not linked to alcoholism and substance abuse. | Goldman D et al. | β | 1998 | β |
| Association analysis in an evolutionary context: cladistic analysis of the DRD2 locus to test for association with alcoholism. | Lobos EA et al. | β | 1998 | β |
| Association study between the -141C Ins/Del and TaqI A polymorphisms of the dopamine D2 receptor gene and alcoholism. | Ishiguro H et al. | β | 1998 | β |
| Biochemical and genetic studies of Caucasian subjects with ethanol-induced flushing reaction. | Ward RJ et al. | β | 1998 | β |
| Common quantitative trait loci for alcohol-related behaviors and CNS neurotensin measures: voluntary ethanol consumption. | Gehle VM et al. | β | 1998 | β |
| Comorbid migraine with aura, anxiety, and depression is associated with dopamine D2 receptor (DRD2) NcoI alleles. | Peroutka SJ et al. | β | 1998 | β |
| D2 and D4 dopamine receptor polymorphisms and personality. | Noble EP et al. | β | 1998 | β |
| D2 dopamine receptor and GABA(A) receptor beta3 subunit genes and alcoholism. | Noble EP et al. | β | 1998 | β |
| Genetic and environmental influences on human behavioral differences. | McGue M et al. | β | 1998 | β |
| Genetic association between reduced P300 amplitude and the DRD2 dopamine receptor A1 allele in children at high risk for alcoholism. | Hill SY et al. | β | 1998 | β |
| Issues and strategies in the genetic analysis of alcoholism and related addictive behaviors. | Schork NJ et al. | β | 1998 | β |
| Linkage of an alcoholism-related severity phenotype to chromosome 16. | Foroud T et al. | β | 1998 | β |
| Modification of alcohol withdrawal by the A9 allele of the dopamine transporter gene. | Schmidt LG et al. | β | 1998 | β |
| The D2 dopamine receptor gene: a review of association studies in alcoholism and phenotypes. | Noble EP | β | 1998 | β |
| The dopamine D2 receptor gene TaqI A polymorphism is not associated with Novelty Seeking, Harm Avoidance and Reward Dependence in healthy subjects. | de Brettes B et al. | β | 1998 | β |
| The genetics of alcoholism. | Goate AM et al. | β | 1998 | β |
| Why different rules are required for polygenic inheritance: lessons from studies of the DRD2 gene. | Comings DE | β | 1998 | β |
| 5-HT2C (HTR2C) serotonin receptor gene polymorphism associated with the human personality trait of reward dependence: interaction with dopamine D4 receptor (D4DR) and dopamine D3 receptor (D3DR) polymorphisms. | Ebstein RP et al. | β | 1997 | β |
| Allelic association of a dopamine transporter gene polymorphism in alcohol dependence with withdrawal seizures or delirium. | Sander T et al. | β | 1997 | β |
| Association between early-onset alcoholism and the dopamine D2 receptor gene. | Kono Y et al. | β | 1997 | β |
| Association of TaqI A polymorphism of dopamine D2 receptor gene and tardive dyskinesia in schizophrenia. | Chen CH et al. | β | 1997 | β |
| Association of the D2 dopamine receptor A1 allele with alcoholism: medical severity of alcoholism and type of controls. | Lawford BR et al. | β | 1997 | β |
| Dopamine D2 receptor gene and alcoholism among four aboriginal groups and Han in Taiwan. | Chen WJ et al. | β | 1997 | β |
| Enhancement of attention processing by Kantroll in healthy humans: a pilot study. | DeFrance JF et al. | β | 1997 | β |
| Finding disease genes. From cystic fibrosis to sarcoidosis. Thomas A. Neff Lecture. | Iannuzzi MC et al. | β | 1997 | β |
| Frequency of the A1/A2 alleles of the D2 dopamine receptor (DRD2) gene in a British, Caucasian control group screened to exclude alcoholism and heavy drinking. | Turner A et al. | β | 1997 | β |
| Genetic markers of alcohol abuse. | Ferguson RA et al. | β | 1997 | β |
| Linkage and association of a functional DRD2 variant [Ser311Cys] and DRD2 markers to alcoholism, substance abuse and schizophrenia in Southwestern American Indians. | Goldman D et al. | β | 1997 | β |
| Neuropsychological functioning in sons of active alcoholic, recovering alcoholic, and social drinking fathers. | Ozkaragoz T et al. | β | 1997 | β |
| The D2 dopamine receptor (DRD2) gene and family stress; interactive effects on cognitive functions in children. | Berman SM et al. | β | 1997 | β |
| The dopamine D4 receptor gene (DRD4) is not associated with alcoholism in three Taiwanese populations: six polymorphisms tested separately and as haplotypes. | Chang FM et al. | β | 1997 | β |
| The medical utility of genomics data in neuropsychiatry: mutational genetics versus association genetics. | Peroutka SJ | β | 1997 | β |
| A brief screening instrument for assessing parental alcoholism in college student populations. | Vail-Smith K et al. | β | 1996 | β |
| A genetic linkage study of the D2 dopamine receptor locus in heavy drinking and alcoholism. | Cook CC et al. | β | 1996 | β |
| Alcoholism and the dopaminergic system: a review. | Noble EP | β | 1996 | β |
| Association between alcoholism and the dopamine D4 receptor gene. | Muramatsu T et al. | β | 1996 | β |
| D2 dopamine receptor gene TaqI A1 and B1 restriction fragment length polymorphisms: enhanced frequencies in psychostimulant-preferring polysubstance abusers. | Persico AM et al. | β | 1996 | β |
| Direct analysis of candidate genes in impulsive behaviours. | Goldman D et al. | β | 1996 | β |
| Dopamine D2 receptor (DRD2) genotype differentiates intravenous drug abusers from alcoholics and non-abusers. | Foley PF et al. | β | 1996 | β |
| Dopamine D2 receptor gene polymorphisms and vulnerability to substance abuse in African Americans. | Berrettini WH et al. | β | 1996 | β |
| Individual and combined effects of ethanol and cocaine on intracellular signals and gene expression. | Torres G et al. | β | 1996 | β |
| Issues in genetic testing for susceptibility to alcoholism: lessons from Alzheimer's disease and Huntington's disease. | Quaid KA et al. | β | 1996 | β |
| Lack of allelic association of dopamine D1 and D2 (TaqIA) receptor gene polymorphisms with reduced dopaminergic sensitivity to alcoholism. | Heinz A et al. | β | 1996 | β |
| Lack of association between TaqI A1 allele of dopamine D2 receptor gene and alcohol-use disorders in atayal natives of Taiwan. | Chen CH et al. | β | 1996 | β |
| No association between alcoholism and multiple polymorphisms at the dopamine D2 receptor gene (DRD2) in three distinct Taiwanese populations. | Lu RB et al. | β | 1996 | β |
| No evidence of association between structural polymorphism at the dopamine D3 receptor locus and alcoholism in the Japanese. | Higuchi S et al. | β | 1996 | β |
| Reduced dopaminergic function in alcoholics is related to severe dependence. | Schmidt LG et al. | β | 1996 | β |
| Reduced fatty acid ethyl ester synthase activity in the white blood cells of alcoholics. | Gorski NP et al. | β | 1996 | β |
| Risk of alcoholism and parental history: gender differences and a possible reporting bias. | Crum RM et al. | β | 1996 | β |
| Substance use disorder exacerbates brain electrophysiological abnormalities in a psychiatrically-ill population. | Braverman ER et al. | β | 1996 | β |
| The biological, social and clinical bases of drug addiction: commentary and debate. | Altman J et al. | β | 1996 | β |
| The D2 dopamine receptor gene, addiction, and personality: clinical correlates in cocaine abusers. | Compton PA et al. | β | 1996 | β |
| The D2 dopamine receptor gene as a determinant of reward deficiency syndrome. | Blum K et al. | β | 1996 | β |
| Adolescent substance abuse. Risk factors and protective factors. | Patton LH | β | 1995 | β |
| Alcoholism among four aboriginal groups in Taiwan: high prevalences and their implications. | Cheng AT et al. | β | 1995 | β |
| Alcoholism: the role of different motivational systems. | Pihl RO et al. | β | 1995 | β |
| Altered brain sensitivity to ethanol in mice after MPTP treatment. | Yanai J et al. | β | 1995 | β |
| Altered striatal dopamine re-uptake site densities in habitually violent and non-violent alcoholics. | Tiihonen J et al. | β | 1995 | β |
| Association and linkage studies of the TAQI A1 allele at the dopamine D2 receptor gene in samples of female and male alcoholics. | Neiswanger K et al. | β | 1995 | β |
| Association of attention-deficit disorder and the dopamine transporter gene. | Cook EH et al. | β | 1995 | β |
| Dopamine D2 receptor gene (DRD2) haplotypes and the defense style questionnaire in substance abuse, Tourette syndrome, and controls. | Comings DE et al. | β | 1995 | β |
| Dopamine D2 receptor gene polymorphisms in Scandinavian chronic alcoholics: a reappraisal. | Blum K et al. | β | 1995 | β |
| DRD4 dopamine receptor genotype and CSF monoamine metabolites in Finnish alcoholics and controls. | Adamson MD et al. | β | 1995 | β |
| Genetic polymorphisms at the rat and murine loci coding for dopamine D2-like receptors. | Scott AW et al. | β | 1995 | β |
| Gene Variability and Vulnerability to Alcoholism. | Doria JJ | β | 1995 | β |
| Group similarities in beliefs concerning the causes of alcohol problems and the effectiveness of means of overcoming problem alcohol use. | Peralta CD et al. | β | 1995 | β |
| Identifying alcoholism vulnerability alleles. | Goldman D | β | 1995 | β |
| Low brain serotonin turnover rate (low CSF 5-HIAA) and impulsive violence. | Virkkunen M et al. | β | 1995 | β |
| Mapping genes for psychiatric disorders and behavioral traits. | McInnes LA et al. | β | 1995 | β |
| Medical disorders of alcoholism. | Lieber CS | β | 1995 | β |
| Molecular Biology. | Goate AM | β | 1995 | β |
| Neuroimaging in alcoholism: CT and MRI results and clinical correlates. | Mann K et al. | β | 1995 | β |
| Preliminary evidence for an association of a dinucleotide repeat polymorphism at the MAOA gene with early onset alcoholism/substance abuse. | Vanyukov MM et al. | β | 1995 | β |
| Reduced visuospatial performance in children with the D2 dopamine receptor A1 allele. | Berman SM et al. | β | 1995 | β |
| What can the DRD2/alcoholism story teach us about association studies in psychiatric genetics? | Neiswanger K et al. | β | 1995 | β |
| Alcoholism and cancer of the larynx: a case-control study in western Washington (United States). | Hedberg K et al. | β | 1994 | β |
| Alcoholism research. A cautionary genetic tale: the sobering story of D2. | Holden C | β | 1994 | β |
| Allele frequencies of the preproenkephalin A (PENK) gene CA repeat in Asians, African-Americans, and Caucasians: lack of evidence for different allele frequencies in alcoholics. | Chan RJ et al. | β | 1994 | β |
| Catecholamine metabolism and psychiatric or behavioral disorders. | Mallet J et al. | β | 1994 | β |
| D2 dopamine receptor gene and cigarette smoking: a reward gene? | Noble EP et al. | β | 1994 | β |
| Dopamine D2 receptor gene expression in rat lines selected for differences in voluntary alcohol consumption. | SyvΓ€lahti EK et al. | β | 1994 | β |
| Dopamine D2-receptor gene polymorphisms in Scandinavian chronic alcoholics. | Geijer T et al. | β | 1994 | β |
| Failure to find evidence for linkage or association between the dopamine D3 receptor gene and schizophrenia. | SabatΓ© O et al. | β | 1994 | β |
| Genetic animal models of alcohol and drug abuse. | Crabbe JC et al. | β | 1994 | β |
| Genetic aspects and risk factors in alcoholism and alcoholic liver disease. | Lumeng L et al. | β | 1994 | β |
| Genetic Aspects of Alcohol Use and Alcoholism in Women. | Svikis DS et al. | β | 1994 | β |
| Genetic association study in psychiatry: analytical evaluation and a recommendation. | Carey G | β | 1994 | β |
| Genetic factors in substance abuse based on studies of Tourette syndrome and ADHD probands and relatives. I. Drug abuse. | Comings DE | β | 1994 | β |
| Genetics of alcoholism: role of the endogenous opioid system. | Gianoulakis C et al. | β | 1994 | β |
| Genotypic differences in brain dopamine receptor function in the DBA/2J and C57BL/6J inbred mouse strains. | Ng GY et al. | β | 1994 | β |
| Human neuroscience at National Institute on Drug Abuse: implications for genetics research. | Gordon HW | β | 1994 | β |
| Monoamine oxidase and homovanillic acid in boys with predispositions to substance abuse. | Gabel S et al. | β | 1994 | β |
| Neurologic effects of alcoholism. | Diamond I et al. | β | 1994 | β |
| No allelic association between Parkinson's disease and dopamine D2, D3, and D4 receptor gene polymorphisms. | Nanko S et al. | β | 1994 | β |
| Prolonged P300 latency in children with the D2 dopamine receptor A1 allele. | Noble EP et al. | β | 1994 | β |
| Striatal D2 dopamine receptor binding characteristics in vivo in patients with alcohol dependence. | Hietala J et al. | β | 1994 | β |
| The D2 dopamine receptor gene and alcoholism: a genetic effect in the liability for alcoholism. | Cook CC et al. | β | 1994 | β |
| The dopamine D2 receptor gene: a genetic risk factor in substance abuse. | Comings DE et al. | β | 1994 | β |
| The Human Genome Project and eugenic concerns. | Garver KL et al. | β | 1994 | β |
| ADH and ALDH genotype profiles in Caucasians with alcohol-related problems and controls. | Gilder FJ et al. | β | 1993 | β |
| [Alcohol, sleep and biological rhythms]. | Aubin HJ et al. | β | 1993 | β |
| Allelic association of the D2 dopamine receptor gene with cocaine dependence. | Noble EP et al. | β | 1993 | β |
| A negative association of schizophrenia with an allele of the HLA DQB1 gene among African-Americans. | Nimgaonkar VL et al. | β | 1993 | β |
| Association between severity of alcoholism and the A1 allele of the dopamine D2 receptor gene TaqI A RFLP in Japanese. | Arinami T et al. | β | 1993 | β |
| Comorbid psychopathy is not associated with increased D2 dopamine receptor TaqI A or B gene marker frequencies in incarcerated substance abusers. | Smith SS et al. | β | 1993 | β |
| D2 dopamine receptor gene and alcoholism. | AmadΓ©o S et al. | β | 1993 | β |
| Densities of dopamine D2 receptors are reduced in CNS regions of alcohol-preferring P rats. | McBride WJ et al. | β | 1993 | β |
| Dopamine transporter gene polymorphisms are not associated with polysubstance abuse. | Persico AM et al. | β | 1993 | β |
| DRD2 dopamine receptor genotype, linkage disequilibrium, and alcoholism in American Indians and other populations. | Goldman D et al. | β | 1993 | β |
| Effects of chronic ethanol intake at a low dose on the rat brain dopaminergic system. | Lograno DE et al. | β | 1993 | β |
| Further neuroendocrine evidence for reduced D2 dopamine receptor function in alcoholism. | Balldin J et al. | β | 1993 | β |
| Genetic predisposition in alcoholism: association of the D2 dopamine receptor TaqI B1 RFLP with severe alcoholics. | Blum K et al. | β | 1993 | β |
| Lack of association between schizophrenia and alleles in the dopamine D3 receptor gene. | JΓΆnsson E et al. | β | 1993 | β |
| P3 in young boys as a predictor of adolescent substance use. | Berman SM et al. | β | 1993 | β |
| Platelets 3H 5-HT uptake in descendants from alcoholic patients: a potential risk factor for alcohol dependence? | Ernouf D et al. | β | 1993 | β |
| Population frequencies of the A1 allele at the dopamine D2 receptor locus. | Barr CL et al. | β | 1993 | β |
| Progress in psychiatry (1) | Michels R et al. | β | 1993 | β |
| Pseudoautosomal region in schizophrenia: sex concordance of the affected sibpairs and the association study with DNA markers. | Ishida T et al. | β | 1993 | β |
| Review of the putative association of dopamine D2 receptor and alcoholism: a meta-analysis. | Pato CN et al. | β | 1993 | β |
| Structures of dopamine receptors. | O'Dowd BF | β | 1993 | β |
| Substance abuse vulnerability and D2 receptor genes. | Uhl G et al. | β | 1993 | β |
| The activity-stress paradigm: possible mechanisms and applications. | Lambert KG | β | 1993 | β |
| The conflict between public health goals and the temperance mentality. | Peele S | β | 1993 | β |
| The D2 dopamine receptor gene and alcoholism: a tempest in a wine cup? | Baron M | β | 1993 | β |
| The D2 dopamine receptor gene: a review of association studies in alcoholism. | Noble EP | β | 1993 | β |
| The primary prevention of addiction in the physician. | Virshup B et al. | β | 1993 | β |
| Why there is no gene for alcoholism. | Devor EJ | β | 1993 | β |
| A gene for alcohol toxicity, not drinking behavior. | Goodman RM | β | 1992 | β |
| Alcoholism and substance abuse among selected southern Cheyenne Indians. | Brown GL et al. | β | 1992 | β |
| Alcoholism and the D2 receptor gene. | Cook BL et al. | β | 1992 | β |
| Alcohol use by children. | Castiglia PT | β | 1992 | β |
| An anti-peptide antibody that recognizes the dopamine D2 receptor from bovine striatum. | Plug MJ et al. | β | 1992 | β |
| A possible genetic association between PROP-tasting and alcoholism. | Pelchat ML et al. | β | 1992 | β |
| Comparison of the expression, transcription and genomic organization of D2 dopamine receptors in outbred and inbred strains of rat. | Luedtke RR et al. | β | 1992 | β |
| D2 dopamine receptor genotype and cerebrospinal fluid homovanillic acid, 5-hydroxyindoleacetic acid and 3-methoxy-4-hydroxyphenylglycol in alcoholics in Finland and the United States. | Goldman D et al. | β | 1992 | β |
| D2 or not D2? | Karp RW | β | 1992 | β |
| Delineation of genetic predisposition to multifactorial disease: a general approach on the threshold of feasibility. | Sobell JL et al. | β | 1992 | β |
| Eugenics, euthanasia and genocide. | Garver KL et al. | β | 1992 | β |
| Exclusion of close linkage of bipolar disorder to dopamine D1 and D2 receptor gene markers. | Mitchell P et al. | β | 1992 | β |
| Genetic aspects of dopamine receptor binding in the mouse and rat brain: an overview. | Vadasz C et al. | β | 1992 | β |
| Lack of association between an RFLP near the D2 dopamine receptor gene and severe alcoholism. | Turner E et al. | β | 1992 | β |
| Mapping psychiatric disease genes: impact of new molecular strategies. | Gilliam TC | β | 1992 | β |
| Medicobiological and genetic studies on alcoholism. Role of metabolic variation and ethnicity on drinking habits, alcohol abuse and alcohol-related mortality. | Agarwal DP et al. | β | 1992 | β |
| Neuroendocrine evidence for reduced dopamine receptor sensitivity in alcoholism. | Balldin JI et al. | β | 1992 | β |
| New insights into activation of the steroid hormone receptor superfamily. | Power RF et al. | β | 1992 | β |
| Patterns of alcoholism inheritance. | Dinwiddie SH | β | 1992 | β |
| Religion and the human genome. | Cole-Turner R | β | 1992 | β |
| Screening and diagnosis of alcoholism in the primary care setting. | Bradley KA | β | 1992 | β |
| Structure and linkage of the D2 dopamine receptor and neural cell adhesion molecule genes on human chromosome 11q23. | Eubanks JH et al. | β | 1992 | β |
| The genetic analysis of human behavior: a new era? | Billings PR et al. | β | 1992 | β |
| Why alcoholism is not a disease. | Heather N | β | 1992 | β |
| Alcohol and aldehyde dehydrogenase genotypes and alcoholism in Chinese men. | Thomasson HR et al. | β | 1991 | β |
| Alcohol use in pregnancy. | Pietrantoni M et al. | β | 1991 | β |
| Analysis of the structure and expression of the human dopamine D2A receptor gene. | Gandelman KY et al. | β | 1991 | β |
| An examination of recent suicides in remote Australia: further information from the Kimberley. | Hunter EM | β | 1991 | β |
| Association of the A1 allele of the D2 dopamine receptor gene with severe alcoholism. | Blum K et al. | β | 1991 | β |
| Clinical and genetic relationships between autism-pervasive developmental disorder and Tourette syndrome: a study of 19 cases. | Comings DE et al. | β | 1991 | β |
| Detection and characterization of additional DNA polymorphisms in the dopamine D2 receptor gene. | Hauge XY et al. | β | 1991 | β |
| Differences and similarities in development of drinking behavior between alcoholic offspring of alcoholics and alcoholic offspring of non-alcoholics. | Alford GS et al. | β | 1991 | β |
| Direct sequencing of the dopamine D2 receptor (DRD2) in schizophrenics reveals three polymorphisms but no structural change in the receptor. | Sarkar G et al. | β | 1991 | β |
| Genetic epidemiology in child psychiatric nursing. Tourette's Syndrome as a model. | Scahill L et al. | β | 1991 | β |
| Genetic linkage analysis and homology relationships of genes located on human chromosome 11q. | Charmley P et al. | β | 1991 | β |
| Identifying genes determining trait differences in behavior and drug response: a comment on 'Quantitative trait loci and psychopharmacology'. | Goldman D et al. | β | 1991 | β |
| Integrated genetic databases in the study of neuropsychiatric diseases: inborn errors of cerebral metabolic pathways? | Jaworski M et al. | β | 1991 | β |
| Medicalizing the drug war. | Fishbein DH | β | 1991 | β |
| Probing the complex genetics of alcoholism. | Holden C | β | 1991 | β |
| Psychopathology and treatment of 30,344 twins in Sweden. II. Heritability estimates of psychiatric diagnosis and treatment in 12,884 twin pairs. | Allgulander C et al. | β | 1991 | β |
| Quantitative trait loci and psychopharmacology. | Plomin R et al. | β | 1991 | β |
| Substance abuse disorders: a psychiatric priority. Group for the Advancement of Psychiatry Committee on Alcoholism and the Addictions. | β | β | 1991 | β |
| Substance use and misuse in childhood and adolescence. | Farrell M et al. | β | 1991 | β |
| Teaching about the human genome project. | Baumiller RC | β | 1991 | β |
| The familial transmission of alcoholism. | Marshall EJ et al. | β | 1991 | β |
| The molecular biology of addictive drugs. | Mackler SA et al. | β | 1991 | β |
| Classically conditioned ethanol stimulus control of a motor behavior. | Silverman PB | β | 1990 | β |
| The use of benzodiazepines in the workplace. | Roy-Byrne PP et al. | β | 1990 | β |
| This and that: genetics, statistics and common sense. | Max B | β | 1990 | β |