Understanding Psychopathology: Melding Behavior Genetics, Personality, and Quantitative Psychology to Develop an Empirically Based Model.
- Authors
- Krueger, Robert F; Markon, Kristian E
- Year
- 2006
- Journal
- Current directions in psychological science
- PMID
- 18392116
- DOI
- 10.1111/j.0963-7214.2006.00418.x
- PMCID
- PMC2288576
Research on psychopathology is at a historical crossroads. New technologies offer the promise of lasting advances in our understanding of the causes of human psychological suffering. Making the best use of these technologies, however, requires an empirically accurate model of psychopathology. Much current research is framed by the model of psychopathology portrayed in current versions of the Diagnostic and Statistical Manual of Mental Disorders (DSM; American Psychiatric Association, 2000). Although the modern DSMs have been fundamental in advancing psychopathology research, recent research also challenges some assumptions made in the DSM-for example, the assumption that all forms of psychopathology are well conceived of as discrete categories. Psychological science has a critical role to play in working through the implications of this research and the challenges it presents. In particular, behavior-genetic, personality, and quantitative-psychological research perspectives can be melded to inform the development of an empirically based model of psychopathology that would constitute an evolution of the DSM.
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| Measurement Invariance of the Pathological Narcissism Inventory and Multimethod Examination of Narcissistic Presentations in Community and Clinical Samples. | Di Pierro R et al. | β | 2023 | β |
| Psychopathology in children: The transdiagnostic contribution of affiliative capacity and inhibitory control. | Palumbo IM et al. | β | 2023 | β |
| Differentiation and comorbidity of bipolar disorder and attention deficit and hyperactivity disorder in children, adolescents, and adults: A clinical and nosological perspective. | Comparelli A et al. | β | 2022 | β |
| Evaluating the validity of animal models of mental disorder: from modeling syndromes to modeling endophenotypes. | van den Berg H | β | 2022 | β |
| Infant Effortful Control Mediates Relations Between Nondirective Parenting and Internalising-Related Child Behaviours in an Autism-Enriched Infant Cohort. | Smith CG et al. | β | 2022 | β |
| Internalizing problems are associated with initiation and past 30-Day use of flavored tobacco products. | Ganz O et al. | β | 2022 | β |
| Suicidal behaviour prediction models using machine learning techniques: A systematic review. | Nordin N et al. | β | 2022 | β |
| Assessment of the structured clinical interview (SCID) for DSM-5 for somatic symptom disorder in general hospital outpatient clinics in China. | Jiang Y et al. | β | 2021 | β |
| Dispositional Negative Emotionality in Childhood and Adolescence Predicts Structural Variation in the Amygdala and Caudal Anterior Cingulate During Early Adulthood: Theoretically and Empirically Based Tests. | Lahey BB et al. | β | 2021 | β |
| Just a phase? Mapping the transition of behavioural problems from childhood to adolescence. | Bathelt J et al. | β | 2021 | β |
| Modeling endophenotypes of suicidal behavior in animals. | Roy B et al. | β | 2021 | β |
| Personality network neuroscience: Promises and challenges on the way toward a unifying framework of individual variability. | Hilger K et al. | β | 2021 | β |
| DSM-5 Level 1 cross-cutting measure in an online sample: evaluating its latent dimensionality and utility detecting nonspecific psychological distress. | Lace JW et al. | β | 2020 | β |
| Receptivity to Tobacco Advertising among Young Adults with Internalizing Problems: Findings from the Population Assessment of Tobacco and Health Study. | Ganz O et al. | β | 2020 | β |
| Research Review: Do parent ratings of infant negative emotionality and self-regulation predict psychopathology in childhood and adolescence? A systematic review and meta-analysis of prospective longitudinal studies. | Kostyrka-Allchorne K et al. | β | 2020 | β |
| Steps Towards a Unified Theory of Psychopathology: The Phase Space of Meaning Model. | Venuleo C et al. | β | 2020 | β |
| The association between general childhood psychopathology and adolescent suicide attempt and self-harm: A prospective, population-based twin study. | O'Reilly LM et al. | β | 2020 | β |
| Associations Between Anxious and Depressive Symptoms and the Recognition of Vocal Socioemotional Expressions in Youth. | Morningstar M et al. | β | 2019 | β |
| Internalizing Profiles of Homeless Adults: Investigating Links Between Perceived Ostracism and Need-Threat. | Van Zalk N et al. | β | 2019 | β |
| Reliability and validity of an internalizing symptom scale based on the adolescent and adult Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA). | Acion L et al. | β | 2019 | β |
| The Narcissism Spectrum Model: A Synthetic View of Narcissistic Personality. | Krizan Z et al. | β | 2018 | β |
| Which Psychopathological Syndromes Could Be Associated with the Risk of Suicide among Substance Users? | Masferrer L et al. | β | 2018 | β |
| A hierarchical causal taxonomy of psychopathology across the life span. | Lahey BB et al. | β | 2017 | β |
| Coping, emotion regulation, and psychopathology in childhood and adolescence: A meta-analysis and narrative review. | Compas BE et al. | β | 2017 | β |
| Facebook usage on smartphones and gray matter volume of the nucleus accumbens. | Montag C et al. | β | 2017 | β |
| Pathways into psychopathology: Modeling the effects of trait emotional intelligence, mindfulness, and irrational beliefs in a clinical sample. | Petrides KV et al. | β | 2017 | β |
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| The Association of Externalizing and Internalizing Problems with Indicators of Intelligence in a Sample of At-Risk Children | Kavish N et al. | β | 2017 | β |
| Using Patterns of Genetic Association to Elucidate Shared Genetic Etiologies Across Psychiatric Disorders. | Cho SB et al. | β | 2017 | β |
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| Disentangling depression and anxiety in relation to neuroticism, extraversion, suicide, and self-harm among adult psychiatric inpatients with serious mental illness. | Subica AM et al. | β | 2016 | β |
| Network analysis of depression and anxiety symptom relationships in a psychiatric sample. | Beard C et al. | β | 2016 | β |
| Posttraumatic Stress Disorder, Hostile Cognitions, and Aggression in Iraq/Afghanistan Era Veterans. | Van Voorhees EE et al. | β | 2016 | β |
| White matter correlates of psychosis-linked traits support continuity between personality and psychopathology. | Grazioplene RG et al. | β | 2016 | β |
| Abnormal reward functioning across substance use disorders and major depressive disorder: Considering reward as a transdiagnostic mechanism. | Baskin-Sommers AR et al. | β | 2015 | β |
| The Relationship Between Psychopathology and a Hierarchical Model of Normal Personality Traits: Evidence From a Psychiatric Patient Sample. | Uliaszek AA et al. | β | 2015 | β |
| Transdiagnostic dimensions of anxiety: Neural mechanisms, executive functions, and new directions. | Sharp PB et al. | β | 2015 | β |
| A new approach to researching the etiology of cannabis use disorder: integrating transmissible and nontransmissible risk within a developmental framework. | Tarter R et al. | β | 2014 | β |
| Empathy as a "risky strength": a multilevel examination of empathy and risk for internalizing disorders. | Tone EB et al. | β | 2014 | β |
| Identical genetic influences underpin behavior problems in adolescence and basic traits of personality. | Lewis GJ et al. | β | 2014 | β |
| Personality assessment inventory internalizing and externalizing structure in veterans with posttraumatic stress disorder: associations with aggression. | Van Voorhees EE et al. | β | 2014 | β |
| The joint structure of major depression, anxiety disorders, and trait negative affect. | Carvalho HW et al. | β | 2014 | β |
| The prevalence of workaholism: a survey study in a nationally representative sample of Norwegian employees. | Andreassen CS et al. | β | 2014 | β |
| Do dopamine gene variants and prenatal smoking interactively predict youth externalizing behavior? | O'Brien TC et al. | β | 2013 | β |
| The role of negative emotionality and impulsivity in depressive/anxiety disorders and alcohol dependence. | Boschloo L et al. | β | 2013 | β |
| Annual research review: phenotypic and causal structure of conduct disorder in the broader context of prevalent forms of psychopathology. | Lahey BB et al. | β | 2012 | β |
| Characteristics of subjects with comorbidity of symptoms of generalized anxiety and major depressive disorders and the corresponding threshold and subthreshold conditions in an Arab general population sample. | Ohaeri JU et al. | β | 2012 | β |
| Diagnostic construct validity of MMPI-2 Restructured Form (MMPI-2-RF) scale scores. | Sellbom M et al. | β | 2012 | β |
| Dimensionality, hierarchical structure, age generalizability, and criterion validity of the GAIN's Behavioral Complexity Scale. | Conrad KJ et al. | β | 2012 | β |
| Future directions in vulnerability to depression among youth: integrating risk factors and processes across multiple levels of analysis. | Hankin BL | β | 2012 | β |
| Intuition, Affect, and Peculiar Beliefs. | Boden MT et al. | β | 2012 | β |
| Is there a general factor of prevalent psychopathology during adulthood? | Lahey BB et al. | β | 2012 | β |
| An experience-sampling study of depressive symptoms and their social context. | Brown LH et al. | β | 2011 | β |
| Development of lifetime comorbidity in the World Health Organization world mental health surveys. | Kessler RC et al. | β | 2011 | β |
| Higher-order genetic and environmental structure of prevalent forms of child and adolescent psychopathology. | Lahey BB et al. | β | 2011 | β |
| Integrating theory-driven and empirically-derived models of personality development and psychopathology: a proposal for DSM V. | Luyten P et al. | β | 2011 | β |
| McLean-Harvard International First-Episode Project: two-year stability of ICD-10 diagnoses in 500 first-episode psychotic disorder patients. | Salvatore P et al. | β | 2011 | β |
| The effects of latent variables in the development of comorbidity among common mental disorders. | Kessler RC et al. | β | 2011 | β |
| The role of latent internalizing and externalizing predispositions in accounting for the development of comorbidity among common mental disorders. | Kessler RC et al. | β | 2011 | β |
| Comorbidity: a network perspective. | Cramer AO et al. | β | 2010 | β |
| Consilient research approaches in studying gene x environment interactions in alcohol research. | Sher KJ et al. | β | 2010 | β |
| Corumination, interpersonal stress generation, and internalizing symptoms: accumulating effects and transactional influences in a multiwave study of adolescents. | Hankin BL et al. | β | 2010 | β |
| McLean-Harvard International First-Episode Project: two-year stability of DSM-IV diagnoses in 500 first-episode psychotic disorder patients. | Salvatore P et al. | β | 2009 | β |
| Predictors of alcohol use prior to deployment in National Guard Soldiers. | Ferrier-Auerbach AG et al. | β | 2009 | β |
| The bright side of being blue: depression as an adaptation for analyzing complex problems. | Andrews PW et al. | β | 2009 | β |
| The structure of common mental disorders: a replication study in a community sample of adolescents and young adults. | Beesdo-Baum K et al. | β | 2009 | β |
| The structure of mental disorders re-examined: is it developmentally stable and robust against additions? | Wittchen HU et al. | β | 2009 | β |
| The Violence Proneness Scale of the DUSI-R predicts adverse outcomes associated with substance abuse. | Kirisci L et al. | β | 2009 | β |
| Advancing psychology as a bio-behavioral science. | Carr JE | β | 2008 | β |
| Cognitive vulnerability-stress model of depression during adolescence: investigating depressive symptom specificity in a multi-wave prospective study. | Hankin BL | β | 2008 | β |
| Recovery and replication of internalizing and externalizing dimensions within the personality assessment inventory. | Ruiz MA et al. | β | 2008 | β |