Ancestry and disease in the age of genomic medicine.
paper
Cited
Public
Unavailable
- Authors
- Rotimi, Charles N; Jorde, Lynn B
- Year
- 2010
- Journal
- The New England journal of medicine
- PMID
- 20942671
- DOI
- 10.1056/NEJMra0911564
No figures extracted from this document.
No chunks — full text not yet ingested.
No entities extracted from this document yet.
No uploaded files.
Not in any collection.
No citations found.
In this knowledge base
| Title | Year | PMID |
|---|---|---|
| Smoking and genetic risk variation across populations of European, Asian, and African American ancestry--a meta-analysis of chromosome 15q25. | 2012 | 22539395 |
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Fractured FRAX: Nurses' role in reckoning with racism in international osteoporosis fracture risk calculations. | Mariano MA et al. | — | 2025 | → |
| Gene variants associated with skin barrier dysfunction in atopic dermatitis: a systematic review and meta-analysis. | Cordeiro PL et al. | — | 2025 | → |
| GenTIGS: a database empowering research and clinical insights on rare genetic disorders with an Indian perspective. | Rashid I et al. | — | 2025 | → |
| Is pharmacogenetics being racialized? An investigation into the reinscription of racial beliefs in modern biomedicine. | Steimle L et al. | — | 2025 | → |
| Subcontinental Genetic Diversity in the <i>All of Us</i> Research Program: Implications for Biomedical Research | Gouveia MH et al. | — | 2025 | — |
| Subcontinental genetic variation in the All of Us Research Program: Implications for biomedical research. | Gouveia MH et al. | — | 2025 | → |
| Frequent gene mutations and the correlations with clinicopathological features in clear cell renal cell carcinoma: preliminary study based on Chinese population and TCGA database. | Zhao Q et al. | — | 2024 | → |
| Genetic Diversity Landscape in African Population: A Review of Implications for Personalized and Precision Medicine. | Sibomana O | — | 2024 | → |
| Inferring ancestry with the hierarchical soft clustering approach tangleGen. | Burger KE et al. | — | 2024 | → |
| The relationship between metabolite mediated immune regulatory imbalance and the occurrence of malignant tumors of bone and articular cartilage: a Mendelian randomization study. | Long K et al. | — | 2024 | → |
| Toward Equitable Kidney Function Estimation in Critical Care Practice: Guidance From the Society of Critical Care Medicine's Diversity, Equity, and Inclusion in Renal Clinical Practice Task Force. | Miano TA et al. | — | 2024 | → |
| Vascular Endothelial Growth Factor and Ischemic Stroke Risk: A Mendelian Randomization Study. | Zhang X et al. | — | 2024 | → |
| 2022 ASHG presidential address-One human race: Billions of genomes. | Rotimi CN | — | 2023 | → |
| Clinical presentation of MEN 2A in index vs. non-index patients. | Machens A et al. | — | 2023 | → |
| Evolutionary Genetics and Admixture in African Populations. | Pfennig A et al. | — | 2023 | → |
| Genes, environment, and African ancestry in cardiometabolic disorders. | Doumatey AP et al. | — | 2023 | → |
| Population designations in biomedical research: Limitations and perspectives. | Gombault C et al. | — | 2023 | → |
| Racial Difference in Efficacy of Golimumab in Ulcerative Colitis. | Greywoode R et al. | — | 2023 | → |
| Reconstruction of the personal information from human genome reads in gut metagenome sequencing data. | Tomofuji Y et al. | — | 2023 | → |
| Skin Phototype and Disease: A Comprehensive Genetic Approach to Pigmentary Traits Pleiotropy Using PRS in the GCAT Cohort. | Farré X et al. | — | 2023 | → |
| Unappreciated subcontinental admixture in Europeans and European Americans and implications for genetic epidemiology studies. | Gouveia MH et al. | — | 2023 | → |
| An evaluation of race-based representation among men participating in clinical trials for prostate cancer and erectile dysfunction. | Saltzman RG et al. | — | 2022 | → |
| An Idealized Clinicogenomic Registry to Engage Underrepresented Populations Using Innovative Technology. | Silva P et al. | — | 2022 | → |
| Association of the rs4646994 in <i>ACE</i> gene with susceptibility to tuberculosis in a region of the Brazilian Amazon. | Porchera DCRF et al. | — | 2022 | → |
| Cardiologists' Perspectives on BiDil and the Use of Race in Drug Prescribing. | Callier SL et al. | — | 2022 | → |
| New insights on the role of human leukocyte antigen complex in primary biliary cholangitis. | Mulinacci G et al. | — | 2022 | → |
| Personalized HLA typing leads to the discovery of novel HLA alleles and tumor-specific HLA variants. | Anzar I et al. | — | 2022 | → |
| Racial Disparities in Glaucoma: From Epidemiology to Pathophysiology. | Siegfried CJ et al. | — | 2022 | → |
| Trabecular Meshwork Mitochondrial Function and Oxidative Stress: Clues to Racial Disparities of Glaucoma. | Wu H et al. | — | 2022 | → |
| Comprehensive classification of anatomical variants of the main biliary ducts. | Janssen BV et al. | — | 2021 | → |
| Demographic representation in clinical trials for cell-based therapy. | Saltzman RG et al. | — | 2021 | → |
| Disparities in Mental Health and Well-Being Among Black and Latinx Patients With Kidney Disease. | Eneanya ND et al. | — | 2021 | → |
| Misrepresenting Race - The Role of Medical Schools in Propagating Physician Bias. | Amutah C et al. | — | 2021 | → |
| Tackling Diversity in Prostate Cancer Clinical Trials: A Report From the Diversity Working Group of the IRONMAN Registry. | McKay RR et al. | — | 2021 | → |
| The Role of Genetic Ancestry as a Risk Factor for Primary Open-angle Glaucoma in African Americans. | Cole BS et al. | — | 2021 | → |
| Evaluating the promise of inclusion of African ancestry populations in genomics. | Bentley AR et al. | — | 2020 | → |
| Genetic variants of mineral metabolism in health and disease. | Robinson-Cohen C | — | 2020 | → |
| High-depth African genomes inform human migration and health. | Choudhury A et al. | — | 2020 | → |
| Race, Ancestry, and Vitamin D Metabolism: The Multi-Ethnic Study of Atherosclerosis. | Hsu S et al. | — | 2020 | → |
| Role of Genetic Ancestry in 1,002 Brazilian Colorectal Cancer Patients From Barretos Cancer Hospital. | Durães RO et al. | — | 2020 | → |
| Age, sex, and setting in the etiology of stroke study (ASSESS): Study design and protocol. | Azarpazhooh MR et al. | — | 2019 | → |
| Cardiologists' Perspectives on Race-Based Drug Labels and Prescribing Within the Context of Treating Heart Failure. | Callier SL et al. | — | 2019 | → |
| Genes, Roommates, and Residence Halls: A Multidimensional Study of the Role of Peer Drinking on College Students' Alcohol Use. | Smith RL et al. | — | 2019 | → |
| Global science meets ethnic diversity: Ian McGonigle interviews GenomeAsia100K Scientific Chairman Stephan Schuster. | McGonigle I et al. | — | 2019 | → |
| The Emergence of Genomic Research in Africa and New Frameworks for Equity in Biomedical Research. | Bentley AR et al. | — | 2019 | → |
| The Genetics of Polycystic Ovary Syndrome: An Overview of Candidate Gene Systematic Reviews and Genome-Wide Association Studies. | Hiam D et al. | — | 2019 | → |
| The Use of Racial Categories in Precision Medicine Research. | Callier SL | — | 2019 | → |
| Genomics and Precision Medicine: Implications for Critical Care. | Kessler C | — | 2018 | → |
| Genotype-specific progression of hereditary medullary thyroid cancer. | Machens A et al. | — | 2018 | → |
| In the Era of Precision Medicine and Big Data, Who Is Normal? | Manrai AK et al. | — | 2018 | → |
| Investigating Black-White disparities in gynecologic oncology: Theories, conceptual models, and applications. | Doll KM | — | 2018 | → |
| SAGE: a comprehensive resource of genetic variants integrating South Asian whole genomes and exomes. | Hariprakash JM et al. | — | 2018 | → |
| The expression of neurological soft signs in two African populations with first-episode schizophrenia. | Ojagbemi A et al. | — | 2018 | → |
| Advancing stroke genomic research in the age of Trans-Omics big data science: Emerging priorities and opportunities. | Owolabi M et al. | — | 2017 | → |
| Diversity and inclusion in genomic research: why the uneven progress? | Bentley AR et al. | — | 2017 | → |
| Genome-Wide Association Studies of Chemotherapeutic Toxicities: Genomics of Inequality. | Mapes B et al. | — | 2017 | → |
| Genotypic and Phenotypic Heterogeneity-Hurdles and Opportunities in the Quest for Hypertension-Related Genes. | Kotchen TA | — | 2017 | → |
| Health regulatory communications of well-established safety-related pharmacogenomics associations in six developed countries: an evaluation of alignment. | Tan-Koi WC et al. | — | 2017 | → |
| MixFit: Methodology for Computing Ancestry-Related Genetic Scores at the Individual Level and Its Application to the Estonian and Finnish Population Studies. | Haller T et al. | — | 2017 | → |
| Pharmacogenomic implications of the evolutionary history of infectious diseases in Africa. | Baker JL et al. | — | 2017 | → |
| Population effect model identifies gene expression predictors of survival outcomes in lung adenocarcinoma for both Caucasian and Asian patients. | Cai G et al. | — | 2017 | → |
| Subtypes of Native American ancestry and leading causes of death: Mapuche ancestry-specific associations with gallbladder cancer risk in Chile. | Lorenzo Bermejo J et al. | — | 2017 | → |
| The genomic landscape of African populations in health and disease. | Rotimi CN et al. | — | 2017 | → |
| Admixture into and within sub-Saharan Africa. | Busby GB et al. | — | 2016 | → |
| Genetic African Ancestry and Markers of Mineral Metabolism in CKD. | Gutiérrez OM et al. | — | 2016 | → |
| H3ABioNet, a sustainable pan-African bioinformatics network for human heredity and health in Africa. | Mulder NJ et al. | — | 2016 | → |
| Nature versus Nurture: Does Genetic Ancestry Alter the Effect of Air Pollution in Children with Asthma? | Sack CS et al. | — | 2016 | → |
| Recent Advances in the Molecular Genetics of Familial Hypertrophic Cardiomyopathy in South Asian Descendants. | Kraker J et al. | — | 2016 | → |
| Social Determinants of Racial Disparities in CKD. | Norton JM et al. | — | 2016 | → |
| Type 2 Diabetes Genetic Predisposition, Obesity, and All-Cause Mortality Risk in the U.S.: A Multiethnic Analysis. | Leong A et al. | — | 2016 | → |
| A reconsideration of the role of self-identified races in epidemiology and biomedical research. | Lorusso L et al. | — | 2015 | → |
| A Single Nucleotide Polymorphism in Catalase Is Strongly Associated with Ovarian Cancer Survival. | Belotte J et al. | — | 2015 | → |
| Clinical and pharmacogenomic implications of genetic variation in a Southern Ethiopian population. | Tekola-Ayele F et al. | — | 2015 | → |
| Contribution of TIMP4 rs3755724 polymorphism to susceptibility to focal epilepsy in Malaysian Chinese. | Haerian BS et al. | — | 2015 | → |
| Demographics of clinical trials participants in pivotal clinical trials for new molecular entity drugs and biologics approved by FDA From 2010 to 2012. | Eshera N et al. | — | 2015 | → |
| First genome-wide association study in an Australian aboriginal population provides insights into genetic risk factors for body mass index and type 2 diabetes. | Anderson D et al. | — | 2015 | → |
| Genome-wide association studies in Africans and African Americans: expanding the framework of the genomics of human traits and disease. | Peprah E et al. | — | 2015 | → |
| Impact of ethnicity on progress of glycaemic control in 131,935 newly diagnosed patients with type 2 diabetes: a nationwide observational study from the Swedish National Diabetes Register. | Rawshani A et al. | — | 2015 | → |
| Racial/ethnic differences in drug disposition and response: review of recently approved drugs. | Ramamoorthy A et al. | — | 2015 | → |
| Self-reported race/ethnicity in the age of genomic research: its potential impact on understanding health disparities. | Mersha TB et al. | — | 2015 | → |
| Stroke genomics in people of African ancestry: charting new paths. | Akinyemi RO et al. | — | 2015 | → |
| Translational Genomics in Low- and Middle-Income Countries: Opportunities and Challenges. | Tekola-Ayele F et al. | — | 2015 | → |
| Accounting for linkage disequilibrium in association analysis of diverse populations. | Charles BA et al. | — | 2014 | → |
| Assessing the quality of studies supporting genetic susceptibility and outcomes of ARDS. | Acosta-Herrera M et al. | — | 2014 | → |
| BiDil in the Clinic: An Interdisciplinary Investigation of Physicians' Prescription Patterns of a Race-Based Therapy. | Maglo KN et al. | — | 2014 | → |
| Creating policy frameworks for public health genomics to benefit developing countries. | Pang T et al. | — | 2014 | → |
| Discussing race-related limitations of genomic testing for colon cancer risk: implications for education and counseling. | Butrick MN et al. | — | 2014 | → |
| Genomic data-sharing: what will be our legacy? | Callier S et al. | — | 2014 | → |
| Medical genetics teaching in Iranian medical schools, especially Ahvaz, south of Iran. | Bijanzadeh M | — | 2014 | → |
| Personalized medicine, availability, and group disparity: an inquiry into how physicians perceive and rate the elements and barriers of personalized medicine. | Petersen KE et al. | — | 2014 | → |
| Pharmacogenomics, ancestry and clinical decision making for global populations. | Ramos E et al. | — | 2014 | → |
| Physicians' knowledge, beliefs, and use of race and human genetic variation: new measures and insights. | Bonham VL et al. | — | 2014 | → |
| Recruitment of Yoruba families from Nigeria for genetic research: experience from a multisite keloid study. | Olaitan PB et al. | — | 2014 | → |
| Transcriptome sequencing of Chinese and Caucasian population identifies ethnic-associated differential transcript abundance of heterogeneous nuclear ribonucleoprotein K (hnRNPK). | Li JW et al. | — | 2014 | → |
| Translating biotechnology to knowledge-based innovation, peace, and development? Deploy a Science Peace Corps--an open letter to world leaders. | Hekim N et al. | — | 2014 | → |
| African American race but not genome-wide ancestry is negatively associated with atrial fibrillation among postmenopausal women in the Women's Health Initiative. | Perez MV et al. | — | 2013 | → |
| Ethical and legal implications of whole genome and whole exome sequencing in African populations. | Wright GE et al. | — | 2013 | → |
| Africa: continent of genome contrasts with implications for biomedical research and health. | Ramsay M | — | 2012 | → |
| African ancestry, early life exposures, and respiratory morbidity in early childhood. | Kumar R et al. | — | 2012 | → |
| Behavior, nutrition and lifestyle in a comprehensive health and disease paradigm: skills and knowledge for a predictive, preventive and personalized medicine. | Trovato GM | — | 2012 | → |
| Genetic variants associated with predisposition to prostate cancer and potential clinical implications. | Goh CL et al. | — | 2012 | → |
| Human genomic disease variants: a neutral evolutionary explanation. | Dudley JT et al. | — | 2012 | → |
| Impaired fasting glucose, ancestry and waist-to-height ratio: main predictors of incident diagnosed diabetes in the Canary Islands. | de León AC et al. | — | 2012 | → |
| Lymphoblastoid cell lines in pharmacogenomic discovery and clinical translation. | Wheeler HE et al. | — | 2012 | → |
| Multi-ethnic reference values for spirometry for the 3-95-yr age range: the global lung function 2012 equations. | Quanjer PH et al. | — | 2012 | → |
| Neurobehavioral assessment in forensic practice. | Woods GW et al. | — | 2012 | → |
| Pituitary tumors in patients with MEN1 syndrome. | Syro LV et al. | — | 2012 | → |
| Role of epigenetics in cancer health disparities. | Mohammed SI et al. | — | 2012 | → |
| Smoking and genetic risk variation across populations of European, Asian, and African American ancestry--a meta-analysis of chromosome 15q25. | Chen LS et al. | — | 2012 | → |
| The genetics of coronary artery disease. | Roberts R et al. | — | 2012 | → |
| [To get rid of "Caucasians". Race and ethnicity in the medical literature]. | Cathébras P | — | 2012 | → |
| Type 2 diabetes risk alleles demonstrate extreme directional differentiation among human populations, compared to other diseases. | Chen R et al. | — | 2012 | → |
| Why personalized medicine will fail if we stay the course. | Ramos E et al. | — | 2012 | → |
| Absence of APOL1 risk variants protects against HIV-associated nephropathy in the Ethiopian population. | Behar DM et al. | — | 2011 | → |
| Association of 8q24.21 loci with the risk of colorectal cancer: a systematic review and meta-analysis. | Haerian MS et al. | — | 2011 | → |
| Awareness of direct-to-consumer genetic tests and use of genetic tests among Puerto Rican adults, 2009. | Ortiz AP et al. | — | 2011 | → |
| Charting a course for genomic medicine from base pairs to bedside. | Green ED et al. | — | 2011 | → |
| Genetic variants of TSLP and asthma in an admixed urban population. | Liu M et al. | — | 2011 | → |
| Genome-wide association studies and susceptibility to infectious diseases. | Newport MJ et al. | — | 2011 | → |
| Genome-wide local ancestry approach identifies genes and variants associated with chemotherapeutic susceptibility in African Americans. | Wheeler HE et al. | — | 2011 | → |
| Health aspects of the pre-departure phase of migration. | Gushulak BD et al. | — | 2011 | → |
| Lack of association of ABCB1 and PXR polymorphisms with response to treatment in epilepsy. | Haerian BS et al. | — | 2011 | → |
| Lack of association of ABCB1 haplotypes on five loci with response to treatment in epilepsy. | Haerian BS et al. | — | 2011 | → |
| Mapping of disease-associated variants in admixed populations. | Shriner D et al. | — | 2011 | → |
| Pharmacogenomic Research in South Africa: Lessons Learned and Future Opportunities in the Rainbow Nation. | Warnich L et al. | — | 2011 | → |
| Pharmacogenomics and adverse drug reactions: the case of statins. | Giorgi MA et al. | — | 2011 | → |
| Publics and vaccinomics: beyond public understanding of science. | Einsiedel EF | — | 2011 | → |
| Race, ancestry, and development of food-allergen sensitization in early childhood. | Kumar R et al. | — | 2011 | → |
| Recent insights into racial differences in bone and mineral metabolism. | Gutiérrez OM | — | 2011 | → |
| [Role of histone modifications in differentiation and effector function of CD8 T cells: update review including genome-wide analysis]. | Araki Y | — | 2011 | → |
| The impact of genetic variability on liver disease in the Hispanic/Latin-American population. | Lau-Corona D et al. | — | 2011 | → |
| The link between mitochondrial DNA hypervariable segment I heteroplasmy and ageing among genetically unrelated Latvians. | Pliss L et al. | — | 2011 | → |
| The relationship between polymorphisms on chromosome 9p21 and age of onset of coronary heart disease in black and white women. | Beckie TM et al. | — | 2011 | → |
| Whole-genome resequencing in pharmacogenomics: moving away from past disparities to globally representative applications. | Drögemöller BI et al. | — | 2011 | → |
| Disease-associated alleles in genome-wide association studies are enriched for derived low frequency alleles relative to HapMap and neutral expectations. | Lachance J | — | 2010 | → |