Electrophysiological indices predict resumption of drinking in sober alcoholics.
- Authors
- Glenn, S W; Sinha, R; Parsons, O A
- Year
- 1993
- Journal
- Alcohol (Fayetteville, N.Y.)
- PMID
- 8442897
- DOI
- 10.1016/0741-8329(93)90086-4
Eighty-nine alcoholics and 54 nonalcoholic controls were tested on measures of late component event-related potentials (ERPs) using a visual "oddball" stimulus task. The alcoholics had just completed inpatient alcoholism treatment programs and were 21-45 days sober. Approximately 13 months later, subjects returned for retesting; alcoholics were classified as resumers or abstainers based on thier drinking patterns during the interest interval. Using the ERP measures from the initial testing session, alcoholics differed significantly from controls in the multivariate analysis and on P300 amplitude (P3A). Resumer alcoholics showed significantly longer N200 latencies (N2L) than abstainer alcoholics. Discriminant function analyses predicting resumer/abstainer status from N2L, P3A and N1A indicated a 63% prediction rate, chi 2 = 5.67, p < 0.02. Addition of N2L to previously tested psychological and social predictor variables indicated an increase in the amount of variance explained. The results support a biopsychosocial model for understanding and predicting relapse in chronic alcoholics.
No figures extracted from this document.
No chunks — full text not yet ingested.
No entities extracted from this document yet.
No uploaded files.
No citations found.
In this knowledge base
| Title | Year | PMID |
|---|---|---|
| Understanding alcohol use disorders with neuroelectrophysiology. | 2014 | 25307587 |
| Event-Related Potentials and Cognitive Function in Alcoholism. | 1995 | 31798064 |
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| 12 h Abstinence-Induced ERP Changes in Young Smokers: Electrophysiological Evidence From a Go/NoGo Study. | Liu C et al. | — | 2019 | → |
| Cognitive training as a component of treatment of alcohol use disorder: A review. | Nixon SJ et al. | — | 2019 | → |
| A review on EEG-based methods for screening and diagnosing alcohol use disorder. | Mumtaz W et al. | — | 2018 | → |
| Context-Specific Inhibition is Related to Craving in Alcohol Use Disorders: A Dangerous Imbalance. | Stein M et al. | — | 2018 | → |
| Event-Related Potentials as Biomarkers of Behavior Change Mechanisms in Substance Use Disorder Treatment. | Houston RJ et al. | — | 2018 | → |
| Understanding alcohol use disorders with neuroelectrophysiology. | Rangaswamy M et al. | — | 2014 | → |
| P300 during response inhibition is associated with ad-lib alcohol consumption in social drinkers. | Jones A et al. | — | 2013 | → |
| How does emotional context modulate response inhibition in alexithymia: electrophysiological evidence from an ERP study. | Zhang L et al. | — | 2012 | → |
| The P300 event-related brain potential as a neurobiological endophenotype for substance use disorders: a meta-analytic investigation. | Euser AS et al. | — | 2012 | → |
| A roadmap for the development and validation of event-related potential biomarkers in schizophrenia research. | Luck SJ et al. | — | 2011 | → |
| Neuroimaging for drug addiction and related behaviors. | Parvaz MA et al. | — | 2011 | → |
| P3a amplitude predicts successful treatment program completion in substance-dependent individuals. | Anderson NE et al. | — | 2011 | → |
| Sleep disturbance as a universal risk factor for relapse in addictions to psychoactive substances. | Brower KJ et al. | — | 2010 | → |
| Association between Val66Met brain-derived neurotrophic factor (BDNF) gene polymorphism and post-treatment relapse in alcohol dependence. | Wojnar M et al. | — | 2009 | → |
| The relationship of N2 and P3 to inhibitory processing of social drinkers in a Go/NoGo task. | Oddy BW et al. | — | 2009 | → |
| Alcohol-related ERP changes recorded from different modalities: a topographic analysis. | Cohen HL et al. | — | 2002 | → |
| [The p300 cognitive event-related potential. II. Individual variability and clinical application in psychopathology]. | Hansenne M | — | 2000 | → |
| Electrophysiology in neuropsychiatric research: a network perspective. | Winterer G et al. | — | 1999 | → |
| Visual P3a in male alcoholics and controls. | Rodriguez Holguin S et al. | — | 1999 | → |
| Visual P3a in male subjects at high risk for alcoholism. | Rodríguez Holguín S et al. | — | 1999 | → |
| Genetic basis of event-related potentials and their relationship to alcoholism and alcohol use. | Porjesz B et al. | — | 1998 | → |
| Neurocognitive deficits in alcoholics and social drinkers: a continuum? | Parsons OA | — | 1998 | → |
| Quantitative EEG (QEEG) predicts relapse in patients with chronic alcoholism and points to a frontally pronounced cerebral disturbance. | Winterer G et al. | — | 1998 | → |
| ERP responses to target and nontarget visual stimuli in alcoholics from VA and community treatment programs. | Glenn SW et al. | — | 1996 | → |
| Event-Related Potentials and Cognitive Function in Alcoholism. | Porjesz B et al. | — | 1995 | → |
| Nonspecific abnormalities in psychiatry: do they reflect an ordered pathway of brain dysfunction? | Tracy JI | — | 1995 | → |
| Assessment of recovery of electrophysiological and neuropsychological functions in chronic alcoholics. | Glenn S et al. | — | 1994 | → |
| Neuropsychological measures and event-related potentials in alcoholics: interrelationships, long-term reliabilities, and prediction of resumption of drinking. | Parsons OA | — | 1994 | → |