Effects of acute social stress on alcohol consumption in healthy subjects.
paper
Cited
Public
Unavailable
- Authors
- de Wit, Harriet; Söderpalm, Anna H V; Nikolayev, Lilia; Young, Elizabeth
- Year
- 2003
- Journal
- Alcoholism, clinical and experimental research
- PMID
- 12966321
- DOI
- 10.1097/01.ALC.0000081617.37539.D6
BACKGROUND: There has been renewed interest in interactions between stress and use of drugs and alcohol. Although there is evidence that stress increases drug use in human drug users and in laboratory animals, the processes by which stress affects drug-motivated behavior are not understood. Here we examined the effects of an acute social stressor (performing a mental arithmetic task in front of an audience) on consumption of ethanol or placebo beverages in healthy social drinkers. METHODS: Thirty-seven men and women, ages 21-35, were randomly assigned to a placebo (n = 15) or ethanol group (n = 22). Subjects participated in two sessions, one with stress (Trier Social Stress Test) the other without stress. In each session, immediately after the stress or no-stress period, subjects consumed the first dose (placebo or 0.3 g/kg of ethanol for men or 0.2 g/kg for women). Then, subjects were allowed to choose up to six more beverages (0.1 g/kg each for the ethanol group or placebo beverages for the placebo group). Measures included percentage of beverage consumed, salivary cortisol level, heart rate, blood pressure, and subjective ratings of mood and drug effect. RESULTS: Subjects in both the placebo and ethanol groups consumed significantly more of their beverages after stress, compared to no stress. Stress increased anxiety, uneasiness, and produced some stimulant-like effects and, in the ethanol group, it dampened some of the acute subjective effects of ethanol. The direct physiologic and mood effects of the stress were fairly short-lived. CONCLUSIONS: It is concluded that acute stress may produce a modest increase in alcohol consumption in healthy, nonproblem social drinkers but that this increase is not directly related to the pharmacological effects of the drug. Nonpharmacological factors may include expectancies, thirst, or nonspecific facilitation of ongoing behaviors.
No figures extracted from this document.
No chunks — full text not yet ingested.
No entities extracted from this document yet.
No uploaded files.
Not in any collection.
No citations found.
In this knowledge base
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| How people decide to consume (more) alcohol when feeling stressed. | Dora J et al. | — | 2026 | → |
| Investigating key latent factors influencing alcohol consumption among the tribal male adolescents in Dooars region, West Bengal. | Das P et al. | — | 2026 | → |
| A systematic review with meta-analysis on the relation between acute stress, alcohol consumption and cortisol levels in individuals with a personal, familial or no alcohol use disorder. | Weckesser LJ et al. | — | 2025 | → |
| Excess after stress-A three-study validation of the salzburg stress drinking scale as a new tool to measure the stress-drinking relationship. | Reichenberger J et al. | — | 2024 | → |
| Reciprocal relations between acute interpersonal negative life events and acute alcohol use: An examination of the 24 h preceding suicide attempts among hospitalized patients. | Saulnier KG et al. | — | 2024 | → |
| Stress-Induced Sensitization of Insula Activation Predicts Alcohol Craving and Alcohol Use in Alcohol Use Disorder. | Bach P et al. | — | 2024 | → |
| The importance of community engagement in experimental stress and substance use research with marginalized groups: Lessons from research with sexual and gender minority populations. | Fahey KML et al. | — | 2024 | → |
| Differential Momentary Reports of Stress and Affect Associated With Alcohol Consumption in Middle-Aged Versus Younger Adults. | Peterson-Sockwell H et al. | — | 2023 | → |
| Role of social context in addiction etiology and recovery. | Strickland JC et al. | — | 2023 | → |
| Stress-related neuropeptide systems as targets for treatment of alcohol addiction: A clinical perspective. | Heilig M | — | 2023 | → |
| The daily association between affect and alcohol use: A meta-analysis of individual participant data. | Dora J et al. | — | 2023 | → |
| Childhood neglect is associated with low affect and high stress in habitual alcohol drinkers. | Peterson H et al. | — | 2022 | → |
| Effects of stress, alcohol prime dose, and sex on ad libitum drinking. | Patock-Peckham JA et al. | — | 2022 | → |
| Risky health behaviors during the COVID-19 pandemic: Evidence from the expenditures on alcohol, non-alcoholic beverages, and tobacco products. | Acharya B et al. | — | 2022 | → |
| The impact of alcohol priming on craving and motivation to drink: a meta-analysis. | Halsall L et al. | — | 2022 | → |
| What is behind the lifestyle risk factors for head and neck cancer? | Iftikhar A et al. | — | 2022 | → |
| Improving Stress Management and Sleep Hygiene in Intelligent Homes. | Leonidis A et al. | — | 2021 | → |
| Interoception and alcohol: Mechanisms, networks, and implications. | Lovelock DF et al. | — | 2021 | → |
| Mood and Changes in Alcohol Consumption in Young Adults during COVID-19 Lockdown: A Model Explaining Associations with Perceived Immune Fitness and Experiencing COVID-19 Symptoms. | Merlo A et al. | — | 2021 | → |
| Stress-induced escalation of alcohol self-administration, anxiety-like behavior, and elevated amygdala Avp expression in a susceptible subpopulation of rats. | Barchiesi R et al. | — | 2021 | → |
| Translational opportunities in animal and human models to study alcohol use disorder. | Nieto SJ et al. | — | 2021 | → |
| An examination of the extent to which mood and context are associated with real-time alcohol consumption. | Monk RL et al. | — | 2020 | → |
| Efficacy of a complex smartphone application for reducing hazardous alcohol consumption: Study protocol for a randomized controlled trial with analysis of in-app user behavior in relation to outcome. | File D et al. | — | 2020 | → |
| Examining the Relationship Between Self-Reported Drinking and In-Laboratory Drinking and Craving: Is There Concordance? | DeMartini KS et al. | — | 2020 | → |
| Craving, cortisol and behavioral alcohol motivation responses to stress and alcohol cue contexts and discrete cues in binge and non-binge drinkers. | Blaine SK et al. | — | 2019 | → |
| Effects of conditioned social fear on ethanol drinking and vice-versa in male mice. | Kornhuber J et al. | — | 2019 | → |
| Hypermethylation of Proopiomelanocortin and Period 2 Genes in Blood Are Associated with Greater Subjective and Behavioral Motivation for Alcohol in Humans. | Gangisetty O et al. | — | 2019 | → |
| Real-time social stress response and subsequent alcohol use initiation among female adolescents. | Cloutier RM et al. | — | 2019 | → |
| Convergent Neuronal Plasticity and Metaplasticity Mechanisms of Stress, Nicotine, and Alcohol. | Ostroumov A et al. | — | 2018 | → |
| Excluded, then inebriated: A preliminary investigation into the role of ostracism on alcohol consumption. | Bacon AK et al. | — | 2018 | → |
| Stress responding in cannabis smokers as a function of trauma exposure, sex, and relapse in the human laboratory. | Chao T et al. | — | 2018 | → |
| Stress vulnerability and alcohol use and consequences: From human laboratory studies to clinical outcomes. | Ramchandani VA et al. | — | 2018 | → |
| The effect of laboratory manipulations of negative affect on alcohol craving and use: A meta-analysis. | Bresin K et al. | — | 2018 | → |
| Understanding Postdisaster Substance Use and Psychological Distress Using Concepts from the Self-Medication Hypothesis and Social Cognitive Theory. | Alexander AC et al. | — | 2018 | → |
| Hypothalamic-Pituitary-Adrenal Reactivity to Acute Stress: an Investigation into the Roles of Perceived Stress and Family Resources. | Obasi EM et al. | — | 2017 | → |
| Acute stress increases ad-libitum alcohol consumption in heavy drinkers, but not through impaired inhibitory control. | McGrath E et al. | — | 2016 | → |
| Concomitant stress potentiates the preference for, and consumption of, ethanol induced by chronic pre-exposure to ethanol. | Morais-Silva G et al. | — | 2016 | → |
| Experimental psychopathology paradigms for alcohol use disorders: Applications for translational research. | Bujarski S et al. | — | 2016 | → |
| High cortisol responders to stress show increased sedation to alcohol compared to low cortisol responders: An alcohol dose-response study. | Brkic S et al. | — | 2016 | → |
| Acute stress increases voluntary consumption of alcohol in undergraduates. | Magrys SA et al. | — | 2015 | → |
| Methods for inducing alcohol craving in individuals with co-morbid alcohol dependence and posttraumatic stress disorder: behavioral and physiological outcomes. | Kwako LE et al. | — | 2015 | → |
| Alcohol intoxication alters cognitive skills mediated by frontal and temporal brain regions. | Magrys SA et al. | — | 2014 | → |
| A social-attributional analysis of alcohol response. | Fairbairn CE et al. | — | 2014 | → |
| Coping motives for drinking affect stress reactivity but not alcohol consumption in a clinical laboratory setting. | Thomas SE et al. | — | 2014 | → |
| Effects of stress and dietary tryptophan enhancement on craving for alcohol in binge and non-binge heavy drinkers. | Nesic J et al. | — | 2014 | → |
| How do we 'learn' addiction? Risk factors and mechanisms getting addicted to alcohol. | Hägele C et al. | — | 2014 | → |
| Stress and alcohol interactions: animal studies and clinical significance. | Spanagel R et al. | — | 2014 | → |
| Stress-related alcohol consumption in heavy drinkers correlates with expression of miR-10a, miR-21, and components of the TAR-RNA-binding protein-associated complex. | Beech RD et al. | — | 2014 | → |
| Does stress increase imitation of drinking behavior? An experimental study in a (semi-)naturalistic context. | Larsen H et al. | — | 2013 | → |
| Increased anxiety, voluntary alcohol consumption and ethanol-induced place preference in mice following chronic psychosocial stress. | Bahi A | — | 2013 | → |
| Yohimbine increases opioid-seeking behavior in heroin-dependent, buprenorphine-maintained individuals. | Greenwald MK et al. | — | 2013 | → |
| Clinical laboratory stressors used to study alcohol-stress relationships. | Thomas S et al. | — | 2012 | → |
| Human laboratory paradigms in alcohol research. | Plebani JG et al. | — | 2012 | → |
| Solitary versus social drinking: an experimental study on effects of social exposures on in situ alcohol consumption. | Kuendig H et al. | — | 2012 | → |
| Stress modulation of drug self-administration: implications for addiction comorbidity with post-traumatic stress disorder. | Logrip ML et al. | — | 2012 | → |
| The effects of repeated corticosterone exposure on the interoceptive effects of alcohol in rats. | Besheer J et al. | — | 2012 | → |
| An acute psychosocial stressor increases drinking in non-treatment-seeking alcoholics. | Thomas SE et al. | — | 2011 | → |
| Anxiety Psychopathology and Alcohol Use among Adolescents: A Critical Review of the Empirical Literature and Recommendations for Future Research. | Blumenthal H et al. | — | 2011 | → |
| Bidirectional interactions between acute psychosocial stress and acute intravenous alcohol in healthy men. | Childs E et al. | — | 2011 | → |
| Effects of stress on alcohol drinking: a review of animal studies. | Becker HC et al. | — | 2011 | → |
| Stress and consumption of alcohol in humans with a Type 1 family history of alcoholism in an experimental laboratory setting. | Gordh AH et al. | — | 2011 | → |
| Stress-induced and cue-induced craving for alcohol in heavy drinkers: Preliminary evidence of genetic moderation by the OPRM1 and CRH-BP genes. | Ray LA | — | 2011 | → |
| The enduring influence of drinking motives on alcohol consumption after fateful trauma. | Beseler CL et al. | — | 2011 | → |
| Alcohol self-administration in rats: Modulation by temporal parameters related to repeated mild social defeat stress. | Caldwell EE et al. | — | 2010 | → |
| Human hypothalamus-pituitary-adrenal axis responses to acute psychosocial stress in laboratory settings. | Foley P et al. | — | 2010 | → |
| Preference conditioning in healthy individuals: correlates with hazardous drinking. | Balodis IM et al. | — | 2010 | → |
| Single-nucleotide polymorphisms in corticotropin releasing hormone receptor 1 gene (CRHR1) are associated with quantitative trait of event-related potential and alcohol dependence. | Chen AC et al. | — | 2010 | → |
| The importance of glucocorticoids in alcohol dependence and neurotoxicity. | Rose AK et al. | — | 2010 | → |
| Offspring of parents with an alcohol use disorder prefer higher levels of brain alcohol exposure in experiments involving computer-assisted self-infusion of ethanol (CASE). | Zimmermann US et al. | — | 2009 | → |
| Sex differences in drug-related stress-system changes: implications for treatment in substance-abusing women. | Fox HC et al. | — | 2009 | → |
| Development and pilot validation of computer-assisted self-infusion of ethanol (CASE): a new method to study alcohol self-administration in humans. | Zimmermann US et al. | — | 2008 | → |
| Stimulant alcohol effects prime within session drinking behavior. | Corbin WR et al. | — | 2008 | → |
| Chronic swim stress alters sensitivity to acute behavioral effects of ethanol in mice. | Boyce-Rustay JM et al. | — | 2007 | → |
| How gene-stress-behavior interactions can promote adolescent alcohol use: the roles of predrinking allostatic load and childhood behavior disorders. | Zimmermann US et al. | — | 2007 | → |
| Stress-induced and alcohol cue-induced craving in recently abstinent alcohol-dependent individuals. | Fox HC et al. | — | 2007 | → |
| Gender specific effects of a mild stressor on alcohol cue reactivity in heavy social drinkers. | Nesic J et al. | — | 2006 | → |
| Genetic association of the human corticotropin releasing hormone receptor 1 (CRHR1) with binge drinking and alcohol intake patterns in two independent samples. | Treutlein J et al. | — | 2006 | → |
| Responses to the Trier Social Stress Test (TSST) in single versus grouped participants. | Childs E et al. | — | 2006 | → |
| Relationships among ventral striatal dopamine release, cortisol secretion, and subjective responses to amphetamine. | Oswald LM et al. | — | 2005 | → |
| The search for the neurobiological basis of vulnerability to drug abuse: using microarrays to investigate the role of stress and individual differences. | Kabbaj M et al. | — | 2004 | → |