Comparability of naevus counts between and within examiners, and comparison with computer image analysis.
- Authors
- Aitken, J F; Green, A; Eldridge, A; Green, L; Pfitzner, J; Battistutta, D; Martin, N G
- Year
- 1994
- Journal
- British journal of cancer
- PMID
- 8123478
- DOI
- 10.1038/bjc.1994.88
- PMCID
- PMC1968854
In the course of an investigation of melanocytic naevus development in Queensland, Australia, whole-body naevus counts of 66 adolescents were performed separately by two nurse examiners on two occasions on average 4 weeks apart. There was good agreement between the two examiners for counts of total naevi on the whole body (intra-class correlation coefficient = 0.96) and at selected subsites (face, neck, back, upper arms, lower arms). Agreement was lower when raised naevi only were counted (0.83). Intra-examiner repeatability was high for both nurses, particularly for the more experienced examiner (intra-class correlation coefficients = 0.98 and 0.91 for total naevi on the whole body), and was consistently better when all naevi were counted rather than naevi of a particular size. Independent counts of naevi on the back using a computer imaging technique were reproducible (intra-class correlation coefficient = 0.92), but showed only moderate agreement with counts by the nurse examiners. Overall, these results demonstrate high comparability of naevus counts between and within similarly trained examiners. They do not support the common practice in epidemiological studies of restricting counts to naevi larger than 2 mm, or of counting raised naevi only.
No figures extracted from this document.
No chunks β full text not yet ingested.
No entities extracted from this document yet.
No uploaded files.
In this knowledge base
| Title | Year | PMID |
|---|---|---|
| Meta-analysis of genome-wide association studies for personality. | 2012 | 21173776 |
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| A common genetic influence on human intensity ratings of sugars and high-potency sweeteners. | Hwang LD et al. | β | 2015 | β |
| Associations between depression and anxiety symptoms and retinal vessel caliber in adolescents and young adults. | Meier MH et al. | β | 2014 | β |
| Meta-analysis of genome-wide association studies for personality. | de Moor MH et al. | β | 2012 | β |
| A genome-wide scan for naevus count: linkage to CDKN2A and to other chromosome regions. | Zhu G et al. | β | 2007 | β |
| Heritability and genetic covariation of sensitivity to PROP, SOA, quinine HCl, and caffeine. | Hansen JL et al. | β | 2006 | β |
| Development and reliability of a brief skin cancer risk assessment tool. | Glanz K et al. | β | 2003 | β |
| Evolution of melanocytic nevi on the faces and necks of adolescents: a 4 y longitudinal study. | Siskind V et al. | β | 2002 | β |
| Genetic influence on the variance in P3 amplitude and latency. | Wright MJ et al. | β | 2001 | β |
| Shared and unique environmental factors determine the ecology of methanogens in humans and rats. | Florin TH et al. | β | 2000 | β |
| Twin study of adolescent genetic susceptibility to mosquito bites using ordinal and comparative rating data. | Kirk KM et al. | β | 2000 | β |
| A major quantitative-trait locus for mole density is linked to the familial melanoma gene CDKN2A: a maximum-likelihood combined linkage and association analysis in twins and their sibs. | Zhu G et al. | β | 1999 | β |
| Genetic and environmental contributions to size, color, shape, and other characteristics of melanocytic naevi in a sample of adolescent twins. | McGregor B et al. | β | 1999 | β |
| Maternal and child constitutional factors and the frequency of melanocytic naevi in children. | Graham A et al. | β | 1999 | β |
| Ultraviolet radiation, melanocytic naevi and their dose-response relationship. | Nguyen TD et al. | β | 1997 | β |
| Reliability of computer image analysis of pigmented skin lesions of Australian adolescents. | Aitken JF et al. | β | 1996 | β |