P300 deficits in adults with attention deficit hyperactivity disorder: a meta-analysis.
paper
Cited
Public
Unavailable
- Authors
- Szuromi, B; Czobor, P; Komlósi, S; Bitter, I
- Year
- 2011
- Journal
- Psychological medicine
- PMID
- 20961477
- DOI
- 10.1017/S0033291710001996
BACKGROUND: The P300 (P3) event-related potential (ERP) component, a possible endophenotype for attention deficit hyperactivity disorder (ADHD), has been widely examined in children, but received little attention in adults. Our objective was to conduct a meta-analysis of P3 studies in adults with ADHD. METHOD: We searched the Medline and PsycINFO databases for controlled studies examining both adult ADHD and matched healthy controls. Six relevant publications were identified for the meta-analysis, which had comparable data across studies with regard to the amplitude of ERP components related to target detection (P3, P3b). Pooled effect size (ES) for P3 amplitude as well as the association of the ES with age and gender were investigated using meta-regression. RESULTS: Comparing the ADHD group versus controls, the pooled effect size for a decrease in P3 amplitude was in the medium range (Cohen's d=-0.55, p=0.0006). Additionally, meta-regression revealed that decrease in P3 amplitude significantly varied with the mean age of ADHD patients (p=0.0087), with a gradual increasing of the difference at higher ages. Results also showed a significant association between the ES and gender, indicating a more pronounced reduction of P3 amplitude in the ADHD group versus controls when females were predominantly represented in the sample. CONCLUSIONS: To our knowledge, this is the first meta-analysis of P3 characteristics in adults with ADHD. It reveals a significantly decreased P3 amplitude during target detection. Our result that the reduction in P3 amplitude increases with age is interpreted in a neurodevelopmental context.
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| Insufficient cognitive resources allocation with compensatory sensory enhancement in children with attention difficulties. | Zhang S et al. | — | 2026 | → |
| The effects of transcranial random noise stimulation on excitation/inhibition balance in ADHD. | Dakwar-Kawar O et al. | — | 2026 | → |
| Age and sex, but not depression or anxiety, predict P3 amplitude during adolescence. | Korom M et al. | — | 2025 | → |
| Beyond childhood: Understanding ADHD in adults. | Hulsey B et al. | — | 2025 | → |
| Clinical response to a single-dose methylphenidate challenge is indicative of treatment response at two months in adults with ADHD. | Parlatini V et al. | — | 2025 | → |
| Impact of visual distractors in virtual reality environments on sustained attention behavioral performance and EEG characteristics. | Ai X et al. | — | 2025 | → |
| Increasing Health Literacy on ADHD: A Cross-Disciplinary Integrative Review Examining the Impact of ADHD on Brain Maturation, Composition and Function and Cognitive Processes Across the Life Course. | Brown LE et al. | — | 2025 | → |
| Methylphenidate and P300 in attention deficit hyperactivity disorder: A systematic review and meta-analysis. | C R Barroso B et al. | — | 2025 | → |
| Modulating cortical excitability and cortical arousal by pupil self-regulation. | Weijs ML et al. | — | 2025 | → |
| P300-based brain-computer interface for communication in assistive technology centres: influence of users' profile on BCI access. | Galiotta V et al. | — | 2025 | → |
| Sustained attention in attention-deficit subjects and the impact of binaural beat stimulation evaluated by behavior and EEG. | Alves-Castro G et al. | — | 2025 | → |
| Aligning Event-Related Potentials with Transcranial Alternating Current Stimulation for Modulation-a Review. | Boetzel C et al. | — | 2024 | → |
| EEG Biomarkers for Autism: Rational, Support, and the Qualification Process. | Hudac CM et al. | — | 2024 | → |
| Neurophysiological measures and correlates of cognitive load in attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD) and dyslexia: A scoping review and research recommendations. | Le Cunff AL et al. | — | 2024 | → |
| Unsupervised Characterization of Prediction Error Markers in Unisensory and Multisensory Streams Reveal the Spatiotemporal Hierarchy of Cortical Information Processing. | Ghosh P et al. | — | 2024 | → |
| Visual placebo and nocebo effects. | Piedimonte A et al. | — | 2024 | → |
| Where do neurodevelopmental conditions fit in transdiagnostic psychiatric frameworks? Incorporating a new neurodevelopmental spectrum. | Michelini G et al. | — | 2024 | → |
| Anodal transcranial direct current stimulation (tDCS) over the left dorsolateral prefrontal cortex improves attentional control in chronically stressed adults. | Liu Y et al. | — | 2023 | → |
| Auditory attention measured by EEG in neurological populations: systematic review of literature and meta-analysis. | Vanbilsen N et al. | — | 2023 | → |
| Dissociable default-mode subnetworks subserve childhood attention and cognitive flexibility: Evidence from deep learning and stereotactic electroencephalography. | Warsi NM et al. | — | 2023 | → |
| Does the Number of Stimuli Influence the Formation of the Endogenous Components of the Event-Related Auditory Evoked Potentials? | Oliveira YM et al. | — | 2023 | → |
| Electrophysiological underpinnings of dysfunctional inhibitory control in adults with attention-deficit/hyperactivity disorder: evidence for reduced NoGo anteriorization. | Papp S et al. | — | 2023 | → |
| Multimodal Virtual Reality-Based Assessment of Adult ADHD: A Feasibility Study in Healthy Subjects. | Wiebe A et al. | — | 2023 | → |
| Neurophysiology of perceptual decision-making and its alterations in attention-deficit hyperactivity disorder (ADHD) | Biabani M et al. | — | 2023 | — |
| P300 Modulation <i>via</i> Transcranial Alternating Current Stimulation in Adult Attention-Deficit/Hyperactivity Disorder: A Crossover Study. | Kannen K et al. | — | 2022 | → |
| What Has Been Learned from Using EEG Methods in Research of ADHD? | McLoughlin G et al. | — | 2022 | → |
| A randomized-controlled neurofeedback trial in adult attention-deficit/hyperactivity disorder. | Barth B et al. | — | 2021 | → |
| Biomarker support for ADHD diagnosis based on Event Related Potentials and scores from an attention test. | Häger LA et al. | — | 2021 | → |
| Brain Network Analysis of EEG Recordings Can Be Used to Assess Cognitive Function in Teenagers With 15q13.3 Microdeletion Syndrome. | Stern T et al. | — | 2021 | → |
| EEG Resting-State and Event-Related Potentials as Markers of Learning Success in Older Adults Following Second Language Training: A Pilot Study. | Kliesch M et al. | — | 2021 | → |
| Electrophysiological correlates of improved executive function following EEG neurofeedback in adult attention deficit hyperactivity disorder. | Deiber MP et al. | — | 2021 | → |
| Electrophysiological modulation of sensory and attentional processes during mind wandering in attention-deficit/hyperactivity disorder. | Bozhilova N et al. | — | 2021 | → |
| P300 Event-Related Potentials Mediate the Relationship Between Child Physical Abuse and Externalizing Behavior. | Cui N et al. | — | 2021 | → |
| Altered proactive control in adults with ADHD: Evidence from event-related potentials during cued task switching. | Sidlauskaite J et al. | — | 2020 | → |
| A multicenter effectiveness trial of QEEG-informed neurofeedback in ADHD: Replication and treatment prediction. | Krepel N et al. | — | 2020 | → |
| Attentional Processes in Children With Attentional Problems or Reading Difficulties as Revealed Using Brain Event-Related Potentials and Their Source Localization. | Santhana Gopalan PR et al. | — | 2020 | → |
| Behavioral and Electrophysiological Correlates of Performance Monitoring and Development in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder. | Liu Y et al. | — | 2020 | → |
| Comparison between conventional and HD-tDCS of the right inferior frontal gyrus in children and adolescents with ADHD. | Breitling C et al. | — | 2020 | → |
| Economical Assessment of Working Memory and Response Inhibition in ADHD Using a Combined <i>n</i>-back/Nogo Paradigm: An ERP Study. | Breitling-Ziegler C et al. | — | 2020 | → |
| Effects of Transcranial Direct Current Stimulation (tDCS) in the Normalization of Brain Activation in Patients with Neuropsychiatric Disorders: A Systematic Review of Neurophysiological and Neuroimaging Studies. | Chan MMY et al. | — | 2020 | → |
| Electrophysiological correlates of spontaneous mind wandering in attention-deficit/hyperactivity disorder. | Bozhilova N et al. | — | 2020 | → |
| ERP indices of an orientation-dependent recognition of the human body schema. | Orlandi A et al. | — | 2020 | → |
| Evidence accumulation during perceptual decisions in humans varies as a function of dorsal frontoparietal organization. | Brosnan MB et al. | — | 2020 | → |
| In Quest of Pathognomonic/Endophenotypic Markers of Attention Deficit Hyperactivity Disorder (ADHD): Potential of EEG-Based Frequency Analysis and ERPs to Better Detect, Prevent and Manage ADHD. | Miranda P et al. | — | 2020 | → |
| Neurocognitive mechanisms underlying working memory encoding and retrieval in Attention-Deficit/Hyperactivity Disorder. | Ortega R et al. | — | 2020 | → |
| Patients with mutations of the Thyroid hormone beta-receptor show an ADHD-like phenotype for performance monitoring: an electrophysiological study. | Uter J et al. | — | 2020 | → |
| The Effect of Tactile Training on Sustained Attention in Young Adults. | Luo Y et al. | — | 2020 | → |
| The Effect of Transcutaneous Auricular Vagal Nerve Stimulation (taVNS) on P3 Event-Related Potentials during a Bayesian Oddball Task. | Warren CV et al. | — | 2020 | → |
| Transcranial Alternating Current Stimulation (tACS) as a Tool to Modulate P300 Amplitude in Attention Deficit Hyperactivity Disorder (ADHD): Preliminary Findings. | Dallmer-Zerbe I et al. | — | 2020 | → |
| Altered Auditory P300 Performance in Parents with Attention Deficit Hyperactivity Disorder Offspring. | Chi MH et al. | — | 2019 | → |
| Decreased resting gamma activity in adult attention deficit/hyperactivity disorder. | Tombor L et al. | — | 2019 | → |
| Overlaps and distinctions between attention deficit/hyperactivity disorder and autism spectrum disorder in young adulthood: Systematic review and guiding framework for EEG-imaging research. | Lau-Zhu A et al. | — | 2019 | → |
| P300 amplitude and latency reflect arithmetic skill: An ERP study of the problem size effect. | Dickson DS et al. | — | 2019 | → |
| Sensory Gating Capacity and Attentional Function in Adults With ADHD: A Preliminary Neurophysiological and Neuropsychological Study. | Micoulaud-Franchi JA et al. | — | 2019 | → |
| tDCS to the left DLPFC modulates cognitive and physiological correlates of executive function in a state-dependent manner. | Dubreuil-Vall L et al. | — | 2019 | → |
| Antisocial behaviour and psychopathy: Uncovering the externalizing link in the P3 modulation. | Pasion R et al. | — | 2018 | → |
| Audio-Visual Spatiotemporal Perceptual Training Enhances the P300 Component in Healthy Older Adults. | Yang W et al. | — | 2018 | → |
| Availability of dopamine transporters and auditory P300 abnormalities in adults with attention-deficit hyperactivity disorder: preliminary results. | Chu CL et al. | — | 2018 | → |
| Event-Related-Potential (ERP) Correlates of Performance Monitoring in Adults With Attention-Deficit Hyperactivity Disorder (ADHD). | Marquardt L et al. | — | 2018 | → |
| Identification of neurophysiological biotypes in attention deficit hyperactivity disorder. | Barth B et al. | — | 2018 | → |
| Shared and Disorder-Specific Event-Related Brain Oscillatory Markers of Attentional Dysfunction in ADHD and Bipolar Disorder. | Michelini G et al. | — | 2018 | → |
| An electrophysiological investigation of reinforcement effects in attention deficit/hyperactivity disorder: Dissociating cue sensitivity from down-stream effects on target engagement and performance. | Chronaki G et al. | — | 2017 | → |
| Genetic correlates of the development of theta event related oscillations in adolescents and young adults. | Chorlian DB et al. | — | 2017 | → |
| Neurophysiological Correlates of Attentional Fluctuation in Attention-Deficit/Hyperactivity Disorder. | Cheung CHM et al. | — | 2017 | → |
| Attention-related EEG markers in adult ADHD. | Hasler R et al. | — | 2016 | → |
| Deficient interference control during working memory updating in adults with ADHD: An event-related potential study. | Stroux D et al. | — | 2016 | → |
| EEG correlates of visual short-term memory as neuro-cognitive endophenotypes of ADHD. | Wiegand I et al. | — | 2016 | → |
| ERP Correlates of Proactive and Reactive Cognitive Control in Treatment-Naïve Adult ADHD. | Grane VA et al. | — | 2016 | → |
| Neurofeedback Therapy for Enhancing Visual Attention: State-of-the-Art and Challenges. | Ordikhani-Seyedlar M et al. | — | 2016 | → |
| Gender modulates the development of theta event related oscillations in adolescents and young adults. | Chorlian DB et al. | — | 2015 | → |
| How does reactivity to frustrative non-reward increase risk for externalizing symptoms? | Gatzke-Kopp LM et al. | — | 2015 | → |
| Adult ADHD and working memory: neural evidence of impaired encoding. | Kim S et al. | — | 2014 | → |
| Effortful control and executive attention in typical and atypical development: an event-related potential study. | Samyn V et al. | — | 2014 | → |
| Heritability and molecular-genetic basis of the P3 event-related brain potential: a genome-wide association study. | Malone SM et al. | — | 2014 | → |
| P3 and provoked aggressive behavior. | Fanning JR et al. | — | 2014 | → |
| Use of EEG to diagnose ADHD. | Lenartowicz A et al. | — | 2014 | → |
| Attention-deficit hyperactivity disorder reduces automatic attention in young adults. | Sable JJ et al. | — | 2013 | → |
| COMT x DRD4 epistasis impacts prefrontal cortex function underlying response control. | Heinzel S et al. | — | 2013 | → |
| Consensus paper of the WFSBP task force on biological markers: biological markers for alcoholism. | Hashimoto E et al. | — | 2013 | → |
| Electrophysiological indices of error monitoring in juvenile and adult attention deficit hyperactivity disorder (ADHD)--a meta-analytic appraisal. | Geburek AJ et al. | — | 2013 | → |
| Electrophysiological indices of response inhibition in a Go/NoGo task predict self-control in a social context. | Nash K et al. | — | 2013 | → |
| Alterations in neural processing and psychopathology in children raised in institutions. | Slopen N et al. | — | 2012 | → |
| Assessment of post-excitatory long-interval cortical inhibition in adult attention-deficit/hyperactivity disorder. | Retz W et al. | — | 2012 | → |
| Multiple Electrophysiological Markers of Visual-Attentional Processing in a Novel Task Directed toward Clinical Use. | Bolduc-Teasdale J et al. | — | 2012 | → |
| The neurobiology and genetics of Attention-Deficit/Hyperactivity Disorder (ADHD): what every clinician should know. | Cortese S | — | 2012 | → |
| Electrophysiological markers of genetic risk for attention deficit hyperactivity disorder. | Tye C et al. | — | 2011 | → |
| Pupillometry and P3 index the locus coeruleus-noradrenergic arousal function in humans. | Murphy PR et al. | — | 2011 | → |