Resting state cortical connectivity reflected in EEG coherence in individuals with autism.
paper
Cited
Public
Unavailable
- Authors
- Murias, Michael; Webb, Sara J; Greenson, Jessica; Dawson, Geraldine
- Year
- 2007
- Journal
- Biological psychiatry
- PMID
- 17336944
- DOI
- 10.1016/j.biopsych.2006.11.012
- PMCID
- PMC2001237
BACKGROUND: Theoretical conceptions of autism spectrum disorder (ASD) and experimental studies of cerebral blood flow suggest abnormalities in connections among distributed neural systems in ASD. METHODS: Functional connectivity was assessed with electroencephalographic coherence between pairs of electrodes in a high-density electrode array in narrow frequency bands among 18 adults with ASD and 18 control adults in an eyes closed resting state. RESULTS: In the theta (3-6 Hz) frequency range, locally elevated coherence was evident for the ASD group, especially within left hemisphere frontal and temporal regions. In the lower alpha range (8-10 Hz), globally reduced coherence was evident for the ASD group within frontal regions and between frontal and all other scalp regions. The ASD group exhibited significantly greater relative power between 3 and 6 Hz and 13-17 Hz and significantly less relative power between 9 and 10 Hz. CONCLUSIONS: Robust patterns of over- and under-connectivity are apparent at distinct spatial and temporal scales in ASD subjects in the eyes closed resting state.
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| Title | Year | PMID |
|---|---|---|
| Association of Polygenic Liability for Alcohol Dependence and EEG Connectivity in Adolescence and Young Adulthood. | 2019 | 31627376 |
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