A comparison of methods to test mediation and other intervening variable effects.
- Authors
- MacKinnon, David P; Lockwood, Chondra M; Hoffman, Jeanne M; West, Stephen G; Sheets, Virgil
- Year
- 2002
- Journal
- Psychological methods
- PMID
- 11928892
- DOI
- 10.1037/1082-989x.7.1.83
- PMCID
- PMC2819363
A Monte Carlo study compared 14 methods to test the statistical significance of the intervening variable effect. An intervening variable (mediator) transmits the effect of an independent variable to a dependent variable. The commonly used R. M. Baron and D. A. Kenny (1986) approach has low statistical power. Two methods based on the distribution of the product and 2 difference-in-coefficients methods have the most accurate Type I error rates and greatest statistical power except in 1 important case in which Type I error rates are too high. The best balance of Type I error and statistical power across all cases is the test of the joint significance of the two effects comprising the intervening variable effect.
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| Implementation Quality of an Early Childhood Parenting Program in Colombia and Child Development. | Bernal R et al. | — | 2023 | → |
| Implications of built and social environments on the academic success among African American youth: testing Strong African American Families intervention effects on parental academic racial socialization. | Murry VM et al. | — | 2023 | → |
| Increased coping motives during the COVID-19 pandemic widen cannabis disparities between sexual minoritized and nonminoritized young adults: A bimonthly assessment of data preceding and spanning the pandemic. | McCabe CJ et al. | — | 2023 | → |
| Inefficiency in Delivery of General Surgery to Black Patients: A National Inpatient Sample Study. | Bliton JN | — | 2023 | → |
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| Medical Mistrust Mediates the Relationship Between Nonconsensual Intersex Surgery and Healthcare Avoidance Among Intersex Adults. | Wang JC et al. | — | 2023 | → |
| Mendelian randomization evidence for the causal effects of socio-economic inequality on human longevity among Europeans. | Ye CJ et al. | — | 2023 | → |
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| Methods for mediation analysis with high-dimensional DNA methylation data: Possible choices and comparisons. | Clark-Boucher D et al. | — | 2023 | → |
| Micronutrients and socio-demographic factors were major predictors of anaemia among the Ethiopian population. | Belay A et al. | — | 2023 | → |
| Mindfulness and Sex Education for Sexual Interest/Arousal Disorder: Mediators and Moderators of Treatment Outcome. | Brotto LA et al. | — | 2023 | → |
| Moderation modelling of COVID-19 digital health literacy and sense of coherence across subjective social class and age among university students in Ghana. | Amoako I et al. | — | 2023 | → |
| Mood Disorders and Aggressive Traits Mediate Effects of Reported Childhood Adversity on Suicide Attempt Risk. | Rabbany JM et al. | — | 2023 | → |
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| Nomophobia and smartphone addiction amidst COVID-19 home confinement: the parallel mediating role of digital gaming and social media tools usage across secondary school students. | Aydin MK et al. | — | 2023 | → |
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| Optimizing digital health technologies to improve therapeutic skill use and acquisition alongside enhanced cognitive-behavior therapy for binge-spectrum eating disorders: Protocol for a randomized controlled trial. | Juarascio AS et al. | — | 2023 | → |
| Pathways from maternal depression to child resilience: Socioeconomic, family, and individual factors in the 2004 Pelotas (Brazil) birth cohort. | Maruyama JM et al. | — | 2023 | → |
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| Personal and Interpersonal Factors Moderate the Relation Between Human-Made Trauma and Hypertension: A Path Analysis Approach. | Bapolisi AM et al. | — | 2023 | → |
| PhyloMed: a phylogeny-based test of mediation effect in microbiome. | Hong Q et al. | — | 2023 | → |
| Positive Impact, Creativity, and Innovative Behavior at Work: The Mediating Role of Basic Needs Satisfaction. | Papachristopoulos K et al. | — | 2023 | → |
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| Predictors of cancer screening behavior of the working population in China based on the information-motivation-behavioral skills model. | Wang Z et al. | — | 2023 | → |
| Preliteracy Skills Mediate the Relation Between Early Speech Sound Production and Subsequent Reading Outcomes. | Mues M et al. | — | 2023 | → |
| Prospective Predictors of Blood Pressure Among African American Men Living with HIV. | Kelly TA et al. | — | 2023 | → |
| Psychological capital and perceived supervisor social support as mediating roles between role stress and work engagement among Chinese clinical nursing teachers: a cross-sectional study. | Sun X et al. | — | 2023 | → |
| Racialized Health Inequities: Quantifying Socioeconomic and Stress Pathways Using Moderated Mediation. | Brown TH et al. | — | 2023 | → |
| Rationale and design of a multisite randomized clinical trial examining an integrated behavioral treatment for veterans with co-occurring chronic pain and opioid use disorder: The pain and opioids integrated treatment in veterans (POSITIVE) trial. | Vowles KE et al. | — | 2023 | → |
| Reducing dietary intake of added sugars could affect the nutritional adequacy of vitamin A in adolescents: the Costa Rica case. | Monge-Rojas R et al. | — | 2023 | → |
| Reducing suicide risk in parentally bereaved youth through promoting effective parenting: testing a developmental cascade model. | Zhang N et al. | — | 2023 | → |
| Relation between white matter integrity, perfusion, and processing speed in early-stage schizophrenia. | Chen F et al. | — | 2023 | → |
| Relationship between perceptions of recurrence risk and depression state among first-episode ischemic stroke patients in rural areas: The mediating role of coping style. | Liu X et al. | — | 2023 | → |
| Relationship between Type D personality and adverse health outcomes in people with type 2 diabetes: The parallel mediating roles of diabetes distress and social isolation. | Lee EH et al. | — | 2023 | → |
| Resilience of infertile families undergoing in vitro fertilization: An application of the double ABC-X model. | Wang JY et al. | — | 2023 | → |
| Respect Your Elders: Generativity and Life Satisfaction in Caregiving Grandparents. | Scott RK et al. | — | 2023 | → |
| Role of positive emotion regulation strategies in the association between childhood trauma and posttraumatic stress disorder among trauma-exposed individuals who use substances. | Kiefer R et al. | — | 2023 | → |
| Self-Controlled Perspective: Nurses' Perceived Social Undermining and Knowledge-Sharing Behavior in Public Hospitals. | Ali M et al. | — | 2023 | → |
| Self-Efficacy as Moderator and Mediator Between Medication Beliefs and Adherence in Elderly Patients with Type 2 Diabetes. | Wu J et al. | — | 2023 | → |
| Self-Identity Matters: An Extended Theory of Planned Behavior to Decode Tourists' Waste Sorting Intentions. | Cao J et al. | — | 2023 | → |
| SGLT2 inhibition, circulating metabolites, and atrial fibrillation: a Mendelian randomization study. | Li J et al. | — | 2023 | → |
| Sharing digital self-monitoring data with others to enhance long-term weight loss: A randomized controlled trial. | Miller NA et al. | — | 2023 | → |
| Socioeconomic disparities in sleep duration are associated with cortical thickness in children. | Hansen M et al. | — | 2023 | → |
| Socio-economic status, psychosocial factors, health behaviours and incidence of dental caries in 12-year-old children living in deprived communities in Manaus, Brazil. | Costa LR et al. | — | 2023 | → |
| Stigma towards patients with mental illness: An online survey of United States nurses. | Kolb K et al. | — | 2023 | → |
| Strengthened social ties in disasters: Threat-awe encourages interdependent worldviews via powerlessness. | Takano R et al. | — | 2023 | → |
| Temporal Associations Between Depression and Hostility in the Context of a Divorce Intervention. | Øverup CS et al. | — | 2023 | → |
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| The Effect of Dads Matter-HV on Father Engagement in Home Visiting Services. | Bellamy JL et al. | — | 2023 | → |
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| The impact of life stress, psychological resources, and proactive behaviors on quality of life among people living with HIV. | Nguyen AL et al. | — | 2023 | → |
| The Influence of Social Media Interactions and Behaviors on Depressive Symptoms Among Sexual and Gender Minority Young Adults in the United States: Protocol for a Mixed Methods Longitudinal Study. | Escobar-Viera C et al. | — | 2023 | → |
| The integrated common-sense model of illness self-regulation: predicting healthy eating, exercise behaviors, and health among individuals at risk of metabolic syndrome. | Zhang H et al. | — | 2023 | → |
| The intergenerational effects of paternal incarceration on children's social and psychological well-being from early childhood to adolescence. | Del Toro J et al. | — | 2023 | → |
| The intervening role of anxiety symptoms in associations between Self-Regulation and prosocial behaviors in U.S. Latino/a college students. | Maiya S et al. | — | 2023 | → |
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| The mediating role of health literacy between the presence of chronic disease and psychological distress among older persons in Xi'an city of China. | Guo K et al. | — | 2023 | → |
| The Prospective Effects of Caregiver Parenting on Behavioral Health Outcomes for Children with Incarcerated Parents: a Family Resilience Perspective. | Berkel C et al. | — | 2023 | → |
| The Relationship between Trait Impulsivity and Everyday Executive Functions among Patients with Type 2 Diabetes Mellitus: The Mediating Effect of Negative Emotions. | Liu N et al. | — | 2023 | → |
| The relationships between stress, coping strategies, and quality of life among gynecologic cancer survivors. | Yeh YC et al. | — | 2023 | → |
| The Role of Emotion Dysregulation in the Association Between Substance Use Stigma and Depressive Symptoms Among Trauma-Exposed, Substance-Using Individuals. | Wang K et al. | — | 2023 | → |
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| The Role of Novelty Satisfaction in Distance Physical Education During the COVID-19 Pandemic: A Self-Determination Theory Perspective. | Hsu WT et al. | — | 2023 | → |
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| The Structural Relationship Between Teacher Support and Willingness to Communicate: The Mediation of L2 Anxiety and the Moderation of Growth Language Mindset. | Hejazi SY et al. | — | 2023 | → |
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| Between Personality Traits and Postpartum Depression: The Mediated Role of Maternal Self-Efficacy. | Han L et al. | — | 2022 | → |
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| Cannabis use and sexual risk among MSM who drink: Understanding why more frequent cannabis users may engage in higher rates of condomless sex. | Bustamante MJ et al. | — | 2022 | → |
| Caregivers' Self-Compassion and Bereaved Children's Adjustment: Testing Caregivers' Mental Health and Parenting as Mediators. | Zhang N et al. | — | 2022 | → |
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| Contingency management and cognitive behavior therapy for smoking cessation among veterans with posttraumatic stress disorder: Design and methodology of a randomized clinical trial. | Wells SY et al. | — | 2022 | → |
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| COVID-19 pandemic stresses and relationships in college students. | Gallegos MI et al. | — | 2022 | → |
| COVID-19 Vaccination in China: Adverse Effects and Its Impact on Health Care Working Decisions on Booster Dose. | Luo C et al. | — | 2022 | → |
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| Disentangling Independent and Mediated Causal Relationships Between Blood Metabolites, Cognitive Factors, and Alzheimer's Disease. | Lord J et al. | — | 2022 | → |
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| Effects of Mindful Emotion Regulation on Parents' Loneliness and Social Support: A Longitudinal Study During the COVID-19 Pandemic in the United States. | Zhang N et al. | — | 2022 | → |
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| Employee Engagement and Innovative Work Behavior Among Chinese Millennials: Mediating and Moderating Role of Work-Life Balance and Psychological Empowerment. | Ali H et al. | — | 2022 | → |
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| Examining the role of problematic drug use in the relationship between discrimination and sleep disturbance in transgender and nonbinary individuals. | Belloir JA et al. | — | 2022 | → |
| Exploring the association between birthweight and breast cancer using summary statistics from a perspective of genetic correlation, mediation, and causality. | Zhang M et al. | — | 2022 | → |
| Exploring the Impact and Path of Environmental Protection Tax on Different Air Pollutant Emissions. | Liu W et al. | — | 2022 | → |
| Exploring the relationships between team leader's conflict management styles and team passion: From the emotional perspective. | Yin J et al. | — | 2022 | → |
| Exploring the value of organizational support, engagement, and psychological wellbeing in the volunteer context. | Dekel G et al. | — | 2022 | → |
| Factors associated with intention to uptake pneumococcal vaccines among Chinese elderly aged 60 years and older during the early stage of COVID-19 pandemic. | Zhou M et al. | — | 2022 | → |
| Gender Scripts and Female Sexual Functioning: The Role of Sexual Pressure and Sexual Subjectivity. | Scappini A et al. | — | 2022 | → |
| GMEPS: a fast and efficient likelihood approach for genome-wide mediation analysis under extreme phenotype sequencing. | Liyanage JSS et al. | — | 2022 | → |
| Heterogeneous environmental regulations and green economic efficiency in China: the mediating role of industrial structure. | Wang G et al. | — | 2022 | → |
| Household air pollution and childhood stunting in China: A prospective cohort study. | Yao M et al. | — | 2022 | → |
| How do compulsory citizenship behaviors affect moral disengagement in organizations? Significance of anger toward the organization during the COVID-19 pandemic. | Yildiz B et al. | — | 2022 | → |
| How Does Media Use Promote the Purchase of Private Medical Insurance? A Moderated Mediation Model. | Shi H et al. | — | 2022 | → |
| How Media Use Influences the Fertility Intentions Among Chinese Women of Reproductive Age: A Perspective of Social Trust. | Ning C et al. | — | 2022 | → |
| How Medical Staff Alleviates Job Burnout through Sports Involvement: The Mediating Roles of Health Anxiety and Self-Efficacy. | Chen X et al. | — | 2022 | → |
| How Mindfulness Affects Life Satisfaction: Based on the Mindfulness-to-Meaning Theory. | Li X et al. | — | 2022 | → |
| Identifying pleiotropic genes for complex phenotypes with summary statistics from a perspective of composite null hypothesis testing. | Wang T et al. | — | 2022 | → |
| <i>In vivo</i> Experience With NRT to Increase Adherence and Smoking Abstinence Among Individuals in the Criminal Legal System: Study Protocol for a Randomized Clinical Trial. | Hawes ES et al. | — | 2022 | → |
| Impacts of Physical Exercise and Media Use on the Physical and Mental Health of People with Obesity: Based on the CGSS 2017 Survey. | Wang H et al. | — | 2022 | → |
| Implementing a mHealth intervention to increase colorectal cancer screening among high-risk cancer survivors treated with radiotherapy in the Childhood Cancer Survivor Study (CCSS). | Henderson TO et al. | — | 2022 | → |
| Improving diabetic patients' adherence to treatment and prevention of cardiovascular disease (Office Guidelines Applied to Practice-IMPACT Study)-a cluster randomized controlled effectiveness trial. | Olomu A et al. | — | 2022 | → |
| Improving well-being for individuals with persistent pain after surgery for breast cancer, lobular carcinoma in situ, or ductal carcinoma in situ: A randomized clinical trial. | Stalls JM et al. | — | 2022 | → |
| Impulsiveness indirectly affects suicidal ideation through depression and simultaneously moderates the indirect effect: A moderated mediation path model. | Zhang J et al. | — | 2022 | → |
| Increasing socioeconomically disadvantaged patients' engagement in breast cancer surgery decision-making through a shared decision-making intervention (A231701CD): protocol for a cluster randomised clinical trial. | Schumacher JR et al. | — | 2022 | → |
| Industrial Coagglomeration, Green Innovation, and Manufacturing Carbon Emissions: Coagglomeration's Dynamic Evolution Perspective. | Zhang L et al. | — | 2022 | → |
| Infant DNA methylation: an early indicator of intergenerational trauma? | Moore SR et al. | — | 2022 | → |
| Influence of positive and negative affect on self-management among patients with early chronic kidney disease during the COVID-19 pandemic: The mediating and suppressing effect of ego depletion. | Cui Y et al. | — | 2022 | → |
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| Interconnectedness Is Associated with a Greater Sense of Civic Duty and Collective Action Participation through Transcendental Awareness and Compassion during COVID-19. | Mak WWS et al. | — | 2022 | → |
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| Investigating the relationship between working time characteristics on musculoskeletal symptoms: a cross sectional study. | Garza JL et al. | — | 2022 | → |
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| Mediators of socioeconomic inequalities in preterm birth: a systematic review. | McHale P et al. | — | 2022 | → |
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| The additive effect of late-life depression and olfactory dysfunction on the risk of dementia was mediated by hypersynchronization of the hippocampus/fusiform gyrus. | Chen B et al. | — | 2021 | → |
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| The Functional Polymorphism of <i>DDAH2</i> rs9267551 Is an Independent Determinant of Arterial Stiffness. | Averta C et al. | — | 2021 | → |
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| The Mediating Effect of Positive Illness Cognitions on Experiential Avoidance and Quality of Life in Breast Cancer Patients. | Han J et al. | — | 2021 | → |
| The mediating effect of skeletal muscle index on the relationship between menarcheal age and bone mineral density in premenopausal women by race/ethnicity. | Ning H et al. | — | 2021 | → |
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| Trickle-Down Effects of Entrepreneurial Bricolage and Business Model Innovation on Employee Creativity: Evidence From Entrepreneurial Internet Firms in China. | Hou F et al. | — | 2021 | → |
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| A comparison of meta-methods for synthesizing indirect effects. | van Zundert CHJ et al. | — | 2020 | → |
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| Law-breaking, fairness, and generalized trust: The mediating role of trust in institutions. | Lo Iacono S | — | 2019 | → |
| Mediating Effect Of The Motivation For Medication Use On Disease Management And Medication Adherence Among Community-Dwelling Patients With Schizophrenia. | Hsieh WL et al. | — | 2019 | → |
| Neighborhood walkability and 12-year changes in cardio-metabolic risk: the mediating role of physical activity. | Chandrabose M et al. | — | 2019 | → |
| Occupational Health and Safety and Turnover Intention in the Ghanaian Power Industry: The Mediating Effect of Organizational Commitment. | Liu S et al. | — | 2019 | → |
| Personality Traits and Career Role Enactment: Career Role Preferences as a Mediator. | de Jong N et al. | — | 2019 | → |
| Psychological Capital and University Students' Entrepreneurial Intention in China: Mediation Effect of Entrepreneurial Capitals. | Zhao J et al. | — | 2019 | → |
| Public service motivation as a mediator of the relationship between job stress and presenteeism: a cross-sectional study from Chinese public hospitals. | Deng J et al. | — | 2019 | → |
| Reorganization of 3D genome structure may contribute to gene regulatory evolution in primates. | Eres IE et al. | — | 2019 | → |
| Self-Efficacy to Limit Drinking Mediates the Association between Attitudes and Alcohol-Related Outcomes. | DiBello AM et al. | — | 2019 | → |
| Self-Regulation in Early and Middle Childhood as a Precursor to Social Adjustment Among Low-Income, Ethnic Minority Children. | Li-Grining CP et al. | — | 2019 | → |
| Sex Differences in the Effect of Nucleus Accumbens Volume on Adolescent Drinking: The Mediating Role of Sensation Seeking in the NCANDA Sample. | Morales AM et al. | — | 2019 | → |
| Sleep SAAF: a responsive parenting intervention to prevent excessive weight gain and obesity among African American infants. | Lavner JA et al. | — | 2019 | → |
| Subjective Emotional Well-Being, Emotional Intelligence, and Mood of Gifted vs. Unidentified Students: A Relationship Model. | Casino-García AM et al. | — | 2019 | → |
| Testing Mediators of Youth Intervention Outcomes Using Single-Case Experimental Designs. | Geuke GGM et al. | — | 2019 | → |
| The importance of assigning responsibility during evaluation in order to increase student satisfaction from physical education classes: A structural equation model. | Leyton Román M et al. | — | 2019 | → |
| The ReThink study: a 3-arm parallel randomized trial of cognitive bias modification, with and without adherence promotion, for adolescent anxiety disorder: trial design and protocol. | Reetz S et al. | — | 2019 | → |
| The role of gender in the associations among posttraumatic stress disorder symptom, severity, difficulties regulating emotions, and alcohol misuse. | Goncharenko S et al. | — | 2019 | → |
| Trauma in the Kashmir Valley and the mediating effect of stressors of daily life on symptoms of posttraumatic stress disorder, depression and anxiety. | Housen T et al. | — | 2019 | → |
| Type C Personality and Depression Among Newly Diagnosed Breast Cancer Patients: The Mediating Role of Sense of Coherence. | Wei M et al. | — | 2019 | → |
| What are the Implications of Excessive Internet Searches for Medical Information by Orthopaedic Patients? | Blackburn J et al. | — | 2019 | → |