Effects of acute and repeated restraint stress on endocannabinoid content in the amygdala, ventral striatum, and medial prefrontal cortex in mice.
paper
Cited
Public
Unavailable
- Authors
- Rademacher, David J; Meier, Sarah E; Shi, Leyu; Ho, W-S Vanessa; Jarrahian, Abbas; Hillard, Cecilia J
- Year
- 2008
- Journal
- Neuropharmacology
- PMID
- 17675104
- DOI
- 10.1016/j.neuropharm.2007.06.012
Endocannabinoid signaling has been implicated in habituation to repeated stress. The hypothesis that repeated exposures to stress alters endocannabinoid signaling in the limbic circuit was tested by restraining male mice for 30 min/day for 1, 7, or 10 days and measuring brain endocannabinoid content. Amygdalar N-arachidonylethanolamine was decreased after 1, 7, and 10 restraint episodes; 2-arachidonylglycerol was increased after the 10th restraint. A similar pattern occurred in the medial prefrontal cortex (mPFC): N-arachidonylethanolamine was decreased after the 7th and 10th restraints and 2-arachidonylglycerol was increased after the 10th restraint. In the ventral striatum, the pattern reversed: N-arachidonylethanolamine was increased after the 10th restraint and 2-arachidonylglycerol was decreased after the 7th restraint. Palmitoylethanolamide contents changed in parallel with N-arachidonylethanolamine in the amygdala and ventral striatum. A single restraint episode did not affect the activity of fatty acid amide hydrolase (FAAH) in any of the brain regions examined. After the 10th restraint, both V(max) and K(m) for N-arachidonylethanolamine were increased in the mPFC; while only the V(max) was increased in the amygdala. On the other hand, the V(max) of FAAH was decreased in ventral striatum after the 10th restraint. After the 10th restraint, the maximum velocity for 2-oleoylglycerol hydrolysis was increased in mPFC; no other changes in 2-oleoylglycerol hydrolysis occurred. Repeated exposure to restraint produced no changes in CB(1) receptor density in any of the areas examined. These studies are consistent with the hypothesis that stress exposure alters endocannabinoid signaling in the brain and that alterations in endocannabinoid signaling occur during habituation to stress.
No figures extracted from this document.
No chunks — full text not yet ingested.
No entities extracted from this document yet.
No uploaded files.
Not in any collection.
No citations found.
In this knowledge base
External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| Electroacupuncture alleviates chronic stress-induced anxiety via excitatory neuron CB1 receptor-dependent suppression of GR/SGK1 signaling in the mPFC. | Hu XF et al. | — | 2026 | → |
| Selective upregulation of fatty acid-binding protein 5 within the basolateral amygdala blunts stress-induced reinstatement of cocaine-seeking behavior in mice. | Roeder N et al. | — | 2026 | → |
| CB<sub>1</sub> receptor signaling: Linking neuroplasticity, neuronal types, and mental health outcomes. | Gao Q et al. | — | 2025 | → |
| Developing a functional non-animal CNS stress model utilizing long-term potentiation with human iPSC-cortical neurons to evaluate therapeutics. | Autar K et al. | — | 2025 | → |
| Effects of pharmacological inhibition of fatty acid amide hydrolase on corticosterone release: a systematic review of preclinical studies. | Pereira CF et al. | — | 2025 | → |
| Fatty acid-binding protein 7 gene deletion promotes decreases in brain cannabinoid type 1 receptor binding. | Lu H et al. | — | 2025 | → |
| Emotional comorbidities in epilepsy result from seizure-induced corticosterone activity. | Gom RC et al. | — | 2024 | → |
| The Effects of Acute Stress on Evoked-cortical Connectivity through Wide-field Optical Mapping of Neural and Hemodynamic Signals. | Kim H et al. | — | 2024 | → |
| The endocannabinoid system is involved in the anxiety-like behavior induced by dual-frequency 2.65/0.8 GHz electromagnetic radiation in mice. | Xue T et al. | — | 2024 | → |
| Therapeutic-like activity of cannabidiolic acid methyl ester in the MK-801 mouse model of schizophrenia: Role for cannabinoid CB1 and serotonin-1A receptors. | Richardson B et al. | — | 2024 | → |
| Disruption of tonic endocannabinoid signalling triggers cellular, behavioural and neuroendocrine responses consistent with a stress response. | Petrie GN et al. | — | 2023 | → |
| Dual Cannabinoid and Orexin Regulation of Anhedonic Behaviour Caused by Prolonged Restraint Stress. | Kim HJJ et al. | — | 2023 | → |
| Endocannabinoid 2-Arachidonoylglycerol Levels in the Anterior Cingulate Cortex, Caudate Putamen, Nucleus Accumbens, and Piriform Cortex Were Upregulated by Chronic Restraint Stress. | Zhai Q et al. | — | 2023 | → |
| Endocannabinoid System and Exogenous Cannabinoids in Depression and Anxiety: A Review. | Hasbi A et al. | — | 2023 | → |
| Metabolic and Transcriptomic Signatures of the Acute Psychological Stress Response in the Mouse Brain. | Lee H et al. | — | 2023 | → |
| Reward enhances resilience to chronic social defeat stress in mice: Neural ECs and mGluR5 mechanism <i>via</i> neuroprotection in VTA and DRN. | Shi P et al. | — | 2023 | → |
| Ventral hippocampal diacylglycerol lipase-alpha deletion decreases avoidance behaviors and alters excitation-inhibition balance. | Kondev V et al. | — | 2023 | → |
| A common genetic variant in fatty acid amide hydrolase is linked to alterations in fear extinction neural circuitry in a racially diverse, nonclinical sample of adults. | Zabik NL et al. | — | 2022 | → |
| Disruption of Tonic Endocannabinoid Signaling Triggers the Generation of a Stress Response | Petrie GN et al. | — | 2022 | — |
| Lipid endocannabinoids in energy metabolism, stress and developmental programming. | Almeida MM et al. | — | 2022 | → |
| Molecular Alterations of the Endocannabinoid System in Psychiatric Disorders. | Navarro D et al. | — | 2022 | → |
| Sex and stressor modality influence acute stress-induced dynamic changes in corticolimbic endocannabinoid levels in adult Sprague Dawley rats. | Vecchiarelli HA et al. | — | 2022 | → |
| Targeting the cannabinoid system to counteract the deleterious effects of stress in Alzheimer's disease. | Shade RD et al. | — | 2022 | → |
| The cannabinoid receptor-1 gene interacts with stressful life events to increase the risk for problematic alcohol use. | Bornscheuer L et al. | — | 2022 | → |
| The Endocannabinoid 2-Arachidonoylglycerol Bidirectionally Modulates Acute and Protracted Effects of Predator Odor Exposure. | Kondev V et al. | — | 2022 | → |
| The endocannabinoid system in social anxiety disorder: from pathophysiology to novel therapeutics. | Ahmed M et al. | — | 2022 | → |
| Amygdalar endocannabinoids are affected by predator odor stress in a sex-specific manner and modulate acoustic startle reactivity in female rats. | Albrechet-Souza L et al. | — | 2021 | → |
| Association of the Fatty Acid Amide Hydrolase C385A Polymorphism With Alcohol Use Severity and Coping Motives in Heavy-Drinking Youth. | Best LM et al. | — | 2021 | → |
| Cannabinoid receptor 1 signalling modulates stress susceptibility and microglial responses to chronic social defeat stress. | Beins EC et al. | — | 2021 | → |
| Cannabis use and posttraumatic stress disorder comorbidity: Epidemiology, biology and the potential for novel treatment approaches. | Kondev V et al. | — | 2021 | → |
| CB1 receptors in corticotropin-releasing factor neurons selectively control the acoustic startle response in male mice. | Ruat J et al. | — | 2021 | → |
| Endocannabinoids, cannabinoids and the regulation of anxiety. | Petrie GN et al. | — | 2021 | → |
| The endocannabinoid system in the amygdala and modulation of fear. | Gunduz-Cinar O | — | 2021 | → |
| The role of endocannabinoid system and TRPV1 receptors in the antidepressant and anxiolytic effects of dipyrone in chronic unpredictable mild stress in mice. | Topuz RD et al. | — | 2021 | → |
| Transcranial direct current stimulation (tDCS) produce anti-anxiety response in acute stress exposure rats via activation of amygdala CB1R. | Fang G et al. | — | 2021 | → |
| Traumatic Stress, Chronic Ethanol Exposure, or the Combination, Alter Cannabinoid System Components in Reward and Limbic Regions of the Mouse Brain. | Piggott VM et al. | — | 2021 | → |
| Cannabinoids as therapeutics for PTSD. | Sbarski B et al. | — | 2020 | → |
| Chronic Psychosocial Stress Causes Increased Anxiety-Like Behavior and Alters Endocannabinoid Levels in the Brain of C57Bl/6J Mice. | Bouter Y et al. | — | 2020 | → |
| Endocannabinoid Signaling Collapse Mediates Stress-Induced Amygdalo-Cortical Strengthening. | Marcus DJ et al. | — | 2020 | → |
| Excitation-Inhibition Imbalance Leads to Alteration of Neuronal Coherence and Neurovascular Coupling under Acute Stress. | Han K et al. | — | 2020 | → |
| Hippocampal 2-Arachidonoyl Glycerol Signaling Regulates Time-of-Day- and Stress-Dependent Effects on Rat Short-Term Memory. | Santori A et al. | — | 2020 | → |
| Protective effects of elevated anandamide on stress and fear-related behaviors: translational evidence from humans and mice. | Mayo LM et al. | — | 2020 | → |
| The role of catecholamines in modulating responses to stress: Sex-specific patterns, implications, and therapeutic potential for post-traumatic stress disorder and opiate withdrawal. | Ross JA et al. | — | 2020 | → |
| Animal models of post-traumatic stress disorder and novel treatment targets. | Aspesi D et al. | — | 2019 | → |
| Cannabinoid Actions on Neural Stem Cells: Implications for Pathophysiology. | Rodrigues RS et al. | — | 2019 | → |
| Endocannabinoids and Fear-Related Behavior in Mice Selectively Bred for High or Low Alcohol Preference. | Kirchhoff AM et al. | — | 2019 | → |
| Ethanol-induced alterations in endocannabinoids and relevant neurotransmitters in the nucleus accumbens of fatty acid amide hydrolase knockout mice. | Pavón FJ et al. | — | 2019 | → |
| Non-Genetic Factors in Schizophrenia. | Stilo SA et al. | — | 2019 | → |
| Stress-Induced Alterations of Norepinephrine Release in the Bed Nucleus of the Stria Terminalis of Mice. | Schmidt KT et al. | — | 2019 | → |
| Upregulation of Anandamide Hydrolysis in the Basolateral Complex of Amygdala Reduces Fear Memory Expression and Indices of Stress and Anxiety. | Morena M et al. | — | 2019 | → |
| Chronic treatment with URB597 ameliorates post-stress symptoms in a rat model of PTSD. | Fidelman S et al. | — | 2018 | → |
| Endocannabinoid system, stress and HPA axis. | Micale V et al. | — | 2018 | → |
| Exploiting the Multifaceted Effects of Cannabinoids on Mood to Boost Their Therapeutic Use Against Anxiety and Depression. | Stampanoni Bassi M et al. | — | 2018 | → |
| Integrating Endocannabinoid Signaling and Cannabinoids into the Biology and Treatment of Posttraumatic Stress Disorder. | Hill MN et al. | — | 2018 | → |
| Prefrontal endocannabinoids, stress controllability and resilience: A hypothesis. | Worley NB et al. | — | 2018 | → |
| Restraint stress in lactating mice alters the levels of sulfur-containing amino acids in milk. | Nishigawa T et al. | — | 2018 | → |
| Role of endocannabinoids in the hippocampus and amygdala in emotional memory and plasticity. | Segev A et al. | — | 2018 | → |
| Aging rather than stress strongly influences amino acid metabolisms in the brain and genital organs of female mice. | Kodaira M et al. | — | 2017 | → |
| Endocannabinoid dysregulation in cognitive and stress-related brain regions in the Nrg1 mouse model of schizophrenia. | Clarke DJ et al. | — | 2017 | → |
| Endocannabinoids: Effectors of glucocorticoid signaling. | Balsevich G et al. | — | 2017 | → |
| Endocannabinoid signaling and memory dynamics: A synaptic perspective. | Drumond A et al. | — | 2017 | → |
| Endocannabinoid signalling modulates susceptibility to traumatic stress exposure. | Bluett RJ et al. | — | 2017 | → |
| Functional Redundancy Between Canonical Endocannabinoid Signaling Systems in the Modulation of Anxiety. | Bedse G et al. | — | 2017 | → |
| Pharmacological inhibition of FAAH activity in rodents: A promising pharmacological approach for psychological-cardiac comorbidity? | Carnevali L et al. | — | 2017 | → |
| Role of beta-catenin and endocannabinoids in the nucleus accumbens in extinction in rats exposed to shock and reminders. | Korem N et al. | — | 2017 | → |
| Seeing through the smoke: Human and animal studies of cannabis use and endocannabinoid signalling in corticolimbic networks. | Silveira MM et al. | — | 2017 | → |
| Stress, Anxiety, and Immunomodulation: A Pharmacological Analysis. | Ray A et al. | — | 2017 | → |
| Synaptic functions of endocannabinoid signaling in health and disease. | Araque A et al. | — | 2017 | → |
| The cannabinoid system and pain. | Woodhams SG et al. | — | 2017 | → |
| The effects of cannabinoid receptors activation and glucocorticoid receptors deactivation in the amygdala and hippocampus on the consolidation of a traumatic event. | Shoshan N et al. | — | 2017 | → |
| The effects of enhancing endocannabinoid signaling and blocking corticotrophin releasing factor receptor in the amygdala and hippocampus on the consolidation of a stressful event. | Aisenberg N et al. | — | 2017 | → |
| The Endocannabinoid System and Anxiety. | Lisboa SF et al. | — | 2017 | → |
| The endocannabinoid system as a target for novel anxiolytic drugs. | Patel S et al. | — | 2017 | → |
| Abnormalities in neuroendocrine stress response in psychosis: the role of endocannabinoids. | Appiah-Kusi E et al. | — | 2016 | → |
| Cannabinoids and Glucocorticoids in the Basolateral Amygdala Modulate Hippocampal-Accumbens Plasticity After Stress. | Segev A et al. | — | 2016 | → |
| Cannabinoids reverse the effects of early stress on neurocognitive performance in adulthood. | Alteba S et al. | — | 2016 | → |
| CB1 receptor antagonism blocks stress-potentiated reinstatement of cocaine seeking in rats. | McReynolds JR et al. | — | 2016 | → |
| Components of the cannabinoid system in the dorsal periaqueductal gray are related to resting heart rate. | Dean C et al. | — | 2016 | → |
| Emotional arousal state influences the ability of amygdalar endocannabinoid signaling to modulate anxiety. | Morena M et al. | — | 2016 | → |
| Endocannabinoid Signaling and the Hypothalamic-Pituitary-Adrenal Axis. | Hillard CJ et al. | — | 2016 | → |
| Evaluation of response to restraint stress by salivary corticosterone levels in adult male mice. | Nohara M et al. | — | 2016 | → |
| Exercise as an adjunctive treatment for cannabis use disorder. | Brellenthin AG et al. | — | 2016 | → |
| Interactions Between Anandamide and Corticotropin-Releasing Factor Signaling Modulate Human Amygdala Function and Risk for Anxiety Disorders: An Imaging Genetics Strategy for Modeling Molecular Interactions. | Demers CH et al. | — | 2016 | → |
| Neurobiological Interactions Between Stress and the Endocannabinoid System. | Morena M et al. | — | 2016 | → |
| Reductions in circulating endocannabinoid 2-arachidonoylglycerol levels in healthy human subjects exposed to chronic stressors. | Yi B et al. | — | 2016 | → |
| Role of hypothalamic cannabinoid receptors in post-stroke depression in rats. | Wang S et al. | — | 2016 | → |
| Sex differences in hippocampal response to endocannabinoids after exposure to severe stress. | Zer-Aviv TM et al. | — | 2016 | → |
| Social Stress and Psychosis Risk: Common Neurochemical Substrates? | Mizrahi R | — | 2016 | → |
| Sustained glucocorticoid exposure recruits cortico-limbic CRH signaling to modulate endocannabinoid function. | Gray JM et al. | — | 2016 | → |
| CB1 receptors modulate affective behaviour induced by neuropathic pain. | Rácz I et al. | — | 2015 | → |
| Corticotropin-releasing hormone drives anandamide hydrolysis in the amygdala to promote anxiety. | Gray JM et al. | — | 2015 | → |
| Endocannabinoid Regulation of Neuroendocrine Systems. | Tasker JG et al. | — | 2015 | → |
| Hypothalamic-Pituitary--Adrenal Axis-Feedback Control. | Keller-Wood M | — | 2015 | → |
| Monoacylglycerol lipase (MGLL) polymorphism rs604300 interacts with childhood adversity to predict cannabis dependence symptoms and amygdala habituation: Evidence from an endocannabinoid system-level analysis. | Carey CE et al. | — | 2015 | → |
| RasGRF1 regulates the hypothalamic-pituitary-adrenal axis specifically in early-adolescent female mice. | Uzturk BG et al. | — | 2015 | → |
| The Role of the Brain's Endocannabinoid System in Pain and Its Modulation by Stress. | Corcoran L et al. | — | 2015 | → |
| Training-Associated Emotional Arousal Shapes Endocannabinoid Modulation of Spatial Memory Retrieval in Rats. | Morena M et al. | — | 2015 | → |
| Translational evidence for a role of endocannabinoids in the etiology and treatment of posttraumatic stress disorder. | Neumeister A et al. | — | 2015 | → |
| A critical role for prefrontocortical endocannabinoid signaling in the regulation of stress and emotional behavior. | McLaughlin RJ et al. | — | 2014 | → |
| Cannabinoid receptor activation prevents the effects of chronic mild stress on emotional learning and LTP in a rat model of depression. | Segev A et al. | — | 2014 | → |
| Cannabinoids prevent the effects of a footshock followed by situational reminders on emotional processing. | Korem N et al. | — | 2014 | → |
| Central anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation. | Bluett RJ et al. | — | 2014 | → |
| Endocannabinoid signaling in the etiology and treatment of major depressive illness. | Hillard CJ et al. | — | 2014 | → |
| Ganaxolone improves behavioral deficits in a mouse model of post-traumatic stress disorder. | Pinna G et al. | — | 2014 | → |
| Impact of stress on prefrontal glutamatergic, monoaminergic and cannabinoid systems. | Lapiz-Bluhm MD | — | 2014 | → |
| Stress-induced dopamine response in subjects at clinical high risk for schizophrenia with and without concurrent cannabis use. | Mizrahi R et al. | — | 2014 | → |
| Stress regulates endocannabinoid-CB1 receptor signaling. | Hillard CJ | — | 2014 | → |
| The endocannabinoid system modulates stress, emotionality, and inflammation. | Crowe MS et al. | — | 2014 | → |
| Amygdala FAAH and anandamide: mediating protection and recovery from stress. | Gunduz-Cinar O et al. | — | 2013 | → |
| Cannabinoids ameliorate impairments induced by chronic stress to synaptic plasticity and short-term memory. | Abush H et al. | — | 2013 | → |
| Cannabinoids and glucocorticoids modulate emotional memory after stress. | Akirav I | — | 2013 | → |
| Diagnostic value of concentration profiles of glucocorticosteroids and endocannabinoids in hair. | Krumbholz A et al. | — | 2013 | → |
| Disruption of fatty acid amide hydrolase activity prevents the effects of chronic stress on anxiety and amygdalar microstructure. | Hill MN et al. | — | 2013 | → |
| Effects of endocannabinoid and endovanilloid systems on aversive memory extinction. | Laricchiuta D et al. | — | 2013 | → |
| Emotional, endocrine and brain anandamide response to social challenge in infant male rats. | Marco EM et al. | — | 2013 | → |
| Neonatal tryptophan depletion and corticosterone supplementation modify emotional responses in adult male mice. | Zoratto F et al. | — | 2013 | → |
| Not all stress is equal: CREB is not necessary for restraint stress reinstatement of cocaine-conditioned reward. | Briand LA et al. | — | 2013 | → |
| Recent progress in understanding the pathophysiology of post-traumatic stress disorder: implications for targeted pharmacological treatment. | Bailey CR et al. | — | 2013 | → |
| Translational evidence for the involvement of the endocannabinoid system in stress-related psychiatric illnesses. | Hill MN et al. | — | 2013 | → |
| Upregulation of CB₁ receptor binding in the ventromedial prefrontal cortex promotes proactive stress-coping strategies following chronic stress exposure. | McLaughlin RJ et al. | — | 2013 | → |
| Acute restraint stress enhances hippocampal endocannabinoid function via glucocorticoid receptor activation. | Wang M et al. | — | 2012 | → |
| Acute stress increases circulating anandamide and other N-acylethanolamines in healthy humans. | Dlugos A et al. | — | 2012 | → |
| Antagonism of cannabinoid 1 receptors reverses the anxiety-like behavior induced by central injections of corticotropin-releasing factor and cocaine withdrawal. | Kupferschmidt DA et al. | — | 2012 | → |
| Cannabinoid receptor involvement in stress-induced cocaine reinstatement: potential interaction with noradrenergic pathways. | Vaughn LK et al. | — | 2012 | → |
| Cannabinoid receptor type 1 antagonism significantly modulates basal and loud noise induced neural and hypothalamic-pituitary-adrenal axis responses in male Sprague-Dawley rats. | Newsom RJ et al. | — | 2012 | → |
| Cannabinoids prevent the development of behavioral and endocrine alterations in a rat model of intense stress. | Ganon-Elazar E et al. | — | 2012 | → |
| Chronic, noninvasive glucocorticoid administration suppresses limbic endocannabinoid signaling in mice. | Bowles NP et al. | — | 2012 | → |
| Endocannabinoid signaling, glucocorticoid-mediated negative feedback, and regulation of the hypothalamic-pituitary-adrenal axis. | Hill MN et al. | — | 2012 | → |
| Endocannabinoid signaling in the amygdala: anatomy, synaptic signaling, behavior, and adaptations to stress. | Ramikie TS et al. | — | 2012 | → |
| Genetic dissection of the role of cannabinoid type-1 receptors in the emotional consequences of repeated social stress in mice. | Dubreucq S et al. | — | 2012 | → |
| Mitigation of post-traumatic stress symptoms by Cannabis resin: a review of the clinical and neurobiological evidence. | Passie T et al. | — | 2012 | → |
| Neural responses to threat and reward interact to predict stress-related problem drinking: A novel protective role of the amygdala. | Nikolova YS et al. | — | 2012 | → |
| Neuroanatomical substrates involved in cannabinoid modulation of defensive responses. | Moreira FA et al. | — | 2012 | → |
| Neuronal populations mediating the effects of endocannabinoids on stress and emotionality. | Häring M et al. | — | 2012 | → |
| Prenatal stress and peripubertal stimulation of the endocannabinoid system differentially regulate emotional responses and brain metabolism in mice. | Macrì S et al. | — | 2012 | → |
| Swim stress differentially affects limbic contents of 2-arachidonoylglycerol and 2-oleoylglycerol. | Roberts CJ et al. | — | 2012 | → |
| The endocannabinoid system in anxiety, fear memory and habituation. | Ruehle S et al. | — | 2012 | → |
| Cb1 receptor-mediated signaling emerges as a novel lead to evidence-based treatment development for stress-related psychopathology. | Bailey CR et al. | — | 2011 | → |
| Chronic restraint stress impairs endocannabinoid mediated suppression of GABAergic signaling in the hippocampus of adult male rats. | Hu W et al. | — | 2011 | → |
| Corticosterone mediates reciprocal changes in CB 1 and TRPV1 receptors in primary sensory neurons in the chronically stressed rat. | Hong S et al. | — | 2011 | → |
| Endocannabinoid influence in drug reinforcement, dependence and addiction-related behaviors. | Serrano A et al. | — | 2011 | → |
| Endocannabinoid-mediated synaptic plasticity and addiction-related behavior. | Sidhpura N et al. | — | 2011 | → |
| Endocannabinoids and stress. | Riebe CJ et al. | — | 2011 | → |
| Enhancement of endocannabinoid signaling with JZL184, an inhibitor of the 2-arachidonoylglycerol hydrolyzing enzyme monoacylglycerol lipase, produces anxiolytic effects under conditions of high environmental aversiveness in rats. | Sciolino NR et al. | — | 2011 | → |
| Pre-training anandamide infusion within the basolateral amygdala impairs plus-maze discriminative avoidance task in rats. | Munguba H et al. | — | 2011 | → |
| Putative role of endocannabinoid signaling in the etiology of depression and actions of antidepressants. | Gorzalka BB et al. | — | 2011 | → |
| Reversible gating of endocannabinoid plasticity in the amygdala by chronic stress: a potential role for monoacylglycerol lipase inhibition in the prevention of stress-induced behavioral adaptation. | Sumislawski JJ et al. | — | 2011 | → |
| Short-term adaptation of conditioned fear responses through endocannabinoid signaling in the central amygdala. | Kamprath K et al. | — | 2011 | → |
| Social encounter with a novel partner in adolescent rats: activation of the central endocannabinoid system. | Marco EM et al. | — | 2011 | → |
| Endocannabinoid-mediated modulation of stress responses: physiological and pathophysiological significance. | Finn DP | — | 2010 | → |
| Functional interactions between stress and the endocannabinoid system: from synaptic signaling to behavioral output. | Hill MN et al. | — | 2010 | → |
| Involvement of the endocannabinoid system in the neurobehavioural effects of stress and glucocorticoids. | Hill MN et al. | — | 2010 | → |
| Social isolation and chronic handling alter endocannabinoid signaling and behavioral reactivity to context in adult rats. | Sciolino NR et al. | — | 2010 | → |
| The effects of infusions of CART 55-102 into the basolateral amygdala on amphetamine-induced conditioned place preference in rats. | Rademacher DJ et al. | — | 2010 | → |
| Adaptations of striatal endocannabinoid system during stress. | Rossi S et al. | — | 2009 | → |
| Chronic ethanol treatment potentiates ethanol-induced increases in interstitial nucleus accumbens endocannabinoid levels in rats. | Alvarez-Jaimes L et al. | — | 2009 | → |
| Endocannabinoids in the rat basolateral amygdala enhance memory consolidation and enable glucocorticoid modulation of memory. | Campolongo P et al. | — | 2009 | → |
| Endocannabinoids mediate acute fear adaptation via glutamatergic neurons independently of corticotropin-releasing hormone signaling. | Kamprath K et al. | — | 2009 | → |
| Integration of endocannabinoid signaling into the neural network regulating stress-induced activation of the hypothalamic-pituitary-adrenal axis. | Gorzalka BB et al. | — | 2009 | → |
| Repeated homotypic stress elevates 2-arachidonoylglycerol levels and enhances short-term endocannabinoid signaling at inhibitory synapses in basolateral amygdala. | Patel S et al. | — | 2009 | → |
| Role of endocannabinoid signaling in anxiety and depression. | Patel S et al. | — | 2009 | → |
| Suppression of amygdalar endocannabinoid signaling by stress contributes to activation of the hypothalamic-pituitary-adrenal axis. | Hill MN et al. | — | 2009 | → |
| Adaptations in endocannabinoid signaling in response to repeated homotypic stress: a novel mechanism for stress habituation. | Patel S et al. | — | 2008 | → |
| Chronic psychoemotional stress impairs cannabinoid-receptor-mediated control of GABA transmission in the striatum. | Rossi S et al. | — | 2008 | → |
| Regulation of endocannabinoid signaling by stress: implications for stress-related affective disorders. | Gorzalka BB et al. | — | 2008 | → |
| Targeting the endocannabinoid system: to enhance or reduce? | Di Marzo V | — | 2008 | → |
| The endocannabinoid system in obesity and type 2 diabetes. | Di Marzo V | — | 2008 | → |
| Inhibition of 2-arachidonoylglycerol catabolism modulates vasoconstriction of rat middle cerebral artery by the thromboxane mimetic, U-46619. | Hillard CJ et al. | — | 2007 | → |