Association of low-voltage alpha EEG with a subtype of alcohol use disorders.
paper
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- Authors
- Enoch, M A; White, K V; Harris, C R; Robin, R W; Ross, J; Rohrbaugh, J W; Goldman, D
- Year
- 1999
- Journal
- Alcoholism, clinical and experimental research
- PMID
- 10470973
BACKGROUND: Neurophysiological traits may identify more homogeneous subgroups of alcoholics. Such discoveries could yield information regarding pathophysiological development, leading to more specific preventive measures and treatments. In an earlier study of 127 individuals, 59 of whom were unrelated, we found that a heritable resting Electroencephalographic (EEG) phenotype, i.e., the low-voltage alpha (LVA) trait, was associated with alcohol use disorders and anxiety disorders. METHODS: We evaluated these findings using an independent, similarly established, dataset of 120 subjects. We also extended the study to a larger set of 149 unrelated individuals from a total sample of 247 subjects for whom psychiatric diagnoses and resting EEG phenotypes were available. Blind-rated psychiatric diagnoses were formulated according to DSM-III-R criteria. RESULTS: In the replication sample, the LVA trait was again more common among subjects with anxiety disorders than among those without. In the total group of unrelated individuals, alcoholics were significantly (3 times) more likely to show the LVA trait than were nonalcoholics. Again, individuals with anxiety disorders were significantly (3 times) more likely to exhibit the LVA trait than were those without anxiety disorders. Of 11 unrelated alcoholics with anxiety disorders, seven showed the LVA trait. It was specifically the LVA trait and not low-amplitude alpha activity that was associated with alcohol use disorders. CONCLUSIONS: The results of this replication study and the analysis of the total sample of unrelated individuals support an association between LVA EEG and the subtype of alcohol use disorders associated with anxiety disorders. The LVA phenotype may be a vulnerability factor for alcohol use disorders and anxiety disorders.
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|---|---|---|---|---|
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| Alterations of Functional Connectivity During the Resting State and Their Associations With Visual Memory in College Students Who Binge Drink. | Kim BM et al. | β | 2020 | β |
| Addiction and stress: An allostatic view. | Koob GF et al. | β | 2019 | β |
| CR-19-0950: Event-related responses to alcohol-related stimuli in Mexican-American young adults: Relation to age, gender, comorbidity and "dark side" symptoms. | Ehlers CL et al. | β | 2019 | β |
| Multivariate Analyses Reveal Biological Components Related to Neuronal Signaling and Immunity Mediating Electroencephalograms Abnormalities in Alcohol-Dependent Individuals from the Collaborative Study on the Genetics of Alcoholism Cohort. | Meda SA et al. | β | 2019 | β |
| Evaluation of Alcohol Preference and Drinking in msP Rats Bearing a <i>Crhr1</i> Promoter Polymorphism. | Logrip ML et al. | β | 2018 | β |
| Pattern recognition of spectral entropy features for detection of alcoholic and control visual ERP's in multichannel EEGs. | Padma Shri TK et al. | β | 2017 | β |
| Whole genome sequence association and ancestry-informed polygenic profile of EEG alpha in a Native American population. | Peng Q et al. | β | 2017 | β |
| An Update on CRF Mechanisms Underlying Alcohol Use Disorders and Dependence. | Quadros IM et al. | β | 2016 | β |
| Advances in Electrophysiological Research. | Kamarajan C et al. | β | 2015 | β |
| Low voltage alpha EEG phenotype is associated with reduced amplitudes of alpha event-related oscillations, increased cortical phase synchrony, and a low level of response to alcohol. | Ehlers CL et al. | β | 2015 | β |
| Corticotropin releasing factor: a key role in the neurobiology of addiction. | Zorrilla EP et al. | β | 2014 | β |
| Genetic psychophysiology: advances, problems, and future directions. | Anokhin AP | β | 2014 | β |
| Heritability and molecular-genetic basis of resting EEG activity: a genome-wide association study. | Malone SM et al. | β | 2014 | β |
| Sex differences in alcohol-related neurobehavioral consequences. | Nixon SJ et al. | β | 2014 | β |
| The Correlation between Electroencephalography Amplitude and Interictal Abnormalities: Audit study. | Al-Rawas SF et al. | β | 2014 | β |
| Understanding alcohol use disorders with neuroelectrophysiology. | Rangaswamy M et al. | β | 2014 | β |
| Behavioral, biological, and chemical perspectives on targeting CRF(1) receptor antagonists to treat alcoholism. | Zorrilla EP et al. | β | 2013 | β |
| Alcoholism-related alterations in spectrum, coherence, and phase synchrony of topical electroencephalogram. | Tcheslavski GV et al. | β | 2012 | β |
| EEG spectral phenotypes: heritability and association with marijuana and alcohol dependence in an American Indian community study. | Ehlers CL et al. | β | 2010 | β |
| Genome-wide association identifies candidate genes that influence the human electroencephalogram. | Hodgkinson CA et al. | β | 2010 | β |
| Quantitative EEG in patients with alcohol-related seizures. | Sand T et al. | β | 2010 | β |
| Chronic alcoholism: insights from neurophysiology. | Campanella S et al. | β | 2009 | β |
| HTR3B is associated with alcoholism with antisocial behavior and alpha EEG power--an intermediate phenotype for alcoholism and co-morbid behaviors. | Ducci F et al. | β | 2009 | β |
| A review of brain oscillations in cognitive disorders and the role of neurotransmitters. | BaΕar E et al. | β | 2008 | β |
| Common genetic origins for EEG, alcoholism and anxiety: the role of CRH-BP. | Enoch MA et al. | β | 2008 | β |
| EEG of chronic marijuana users during abstinence: relationship to years of marijuana use, cerebral blood flow and thyroid function. | Herning RI et al. | β | 2008 | β |
| EEG-vigilance differences between patients with borderline personality disorder, patients with obsessive-compulsive disorder and healthy controls. | Hegerl U et al. | β | 2008 | β |
| Neurophysiological and genetic distinctions between pure and comorbid anxiety disorders. | Enoch MA et al. | β | 2008 | β |
| P3 components of the event-related potential and marijuana dependence in Southwest California Indians. | Ehlers CL et al. | β | 2008 | β |
| Transdermal nicotine administration and the electroencephalographic activity of substance abusers in treatment. | Ceballos NA et al. | β | 2008 | β |
| Uncovering genes for cognitive (dys)function and predisposition for alcoholism spectrum disorders: a review of human brain oscillations as effective endophenotypes. | Rangaswamy M et al. | β | 2008 | β |
| Association of EEG alpha variants and alpha power with alcohol dependence in Mexican American young adults. | Ehlers CL et al. | β | 2007 | β |
| Electrophysiological responses to affective stimuli in Mexican Americans: Relationship to alcohol dependence and personality traits. | Criado JR et al. | β | 2007 | β |
| GABAA receptors in the thalamus: alpha4 subunit expression and alcohol sensitivity. | Jia F et al. | β | 2007 | β |
| Clinical correlates of quantitative EEG alterations in alcoholic patients. | Coutin-Churchman P et al. | β | 2006 | β |
| Genetics of human brain oscillations. | Begleiter H et al. | β | 2006 | β |
| Using the brain P300 response to identify novel phenotypes reflecting genetic vulnerability for adolescent substance misuse. | Yoon HH et al. | β | 2006 | β |
| BDNF variation and mood disorders: a novel functional promoter polymorphism and Val66Met are associated with anxiety but have opposing effects. | Jiang X et al. | β | 2005 | β |
| Effects of alcohol on spontaneous neuronal oscillations: a combined magnetoencephalography and electroencephalography study. | Nikulin VV et al. | β | 2005 | β |
| The utility of neurophysiological markers in the study of alcoholism. | Porjesz B et al. | β | 2005 | β |
| EEG alpha variants and alpha power in Hispanic American and white non-Hispanic American young adults with a family history of alcohol dependence. | Ehlers CL et al. | β | 2004 | β |
| Age-dependent changes in electroencephalographic responses to alcohol consumption in subjects with aldehyde dehydrogenase-2 genetic variations. | Nishimura FT et al. | β | 2003 | β |
| Alcoholism and human electrophysiology. | Porjesz B et al. | β | 2003 | β |
| Association analysis of exonic variants of the GABA(B)-receptor gene and alpha electroencephalogram voltage in normal subjects and alcohol-dependent patients. | Winterer G et al. | β | 2003 | β |
| EEG and ERP profiles in the high alcohol preferring (HAP) and low alcohol preferring (LAP) mice: relationship to ethanol preference. | Slawecki CJ et al. | β | 2003 | β |
| EEG deficits in chronic marijuana abusers during monitored abstinence: preliminary findings. | Herning RI et al. | β | 2003 | β |
| EEG low-voltage alpha and alpha power in African American young adults: relation to family history of alcoholism. | Ehlers CL et al. | β | 2003 | β |
| EEG phenotype in alcoholism: increased coherence in the depressive subtype. | Winterer G et al. | β | 2003 | β |
| Genetic origins of anxiety in women: a role for a functional catechol-O-methyltransferase polymorphism. | Enoch MA et al. | β | 2003 | β |
| Genetics of alcoholism using intermediate phenotypes. | Enoch MA et al. | β | 2003 | β |
| Pharmacogenomics of alcohol response and addiction. | Enoch MA | β | 2003 | β |
| Clinical utility of EEG in alcohol-related seizures. | Sand T et al. | β | 2002 | β |
| Alcohol use disorders and anxiety disorders: relation to the P300 event-related potential. | Enoch MA et al. | β | 2001 | β |
| EEG asymmetry: relationship to mood and risk for alcoholism in Mission Indian youth. | Ehlers CL et al. | β | 2001 | β |
| Effects of age and parental history of alcoholism on EEG findings in mission Indian children and adolescents. | Ehlers CL et al. | β | 2001 | β |
| The genetics of alcoholism and alcohol abuse. | Enoch MA et al. | β | 2001 | β |
| Visual P3 findings in Mission Indian youth: relationship to family history of alcohol dependence and behavioral problems. | Ehlers CL et al. | β | 2001 | β |