Depression, chronic diseases, and decrements in health: results from the World Health Surveys.
paper
Cited
Public
Unavailable
- Authors
- Moussavi, Saba; Chatterji, Somnath; Verdes, Emese; Tandon, Ajay; Patel, Vikram; Ustun, Bedirhan
- Year
- 2007
- Journal
- Lancet (London, England)
- PMID
- 17826170
- DOI
- 10.1016/S0140-6736(07)61415-9
BACKGROUND: Depression is an important public-health problem, and one of the leading causes of disease burden worldwide. Depression is often comorbid with other chronic diseases and can worsen their associated health outcomes. Few studies have explored the effect of depression, alone or as a comorbidity, on overall health status. METHODS: The WHO World Health Survey (WHS) studied adults aged 18 years and older to obtain data for health, health-related outcomes, and their determinants. Prevalence of depression in respondents based on ICD-10 criteria was estimated. Prevalence values for four chronic physical diseases--angina, arthritis, asthma, and diabetes--were also estimated using algorithms derived via a Diagnostic Item Probability Study. Mean health scores were constructed using factor analysis and compared across different disease states and demographic variables. The relation of these disease states to mean health scores was determined through regression modelling. FINDINGS: Observations were available for 245 404 participants from 60 countries in all regions of the world. Overall, 1-year prevalence for ICD-10 depressive episode alone was 3.2% (95% CI 3.0-3.5); for angina 4.5% (4.3-4.8); for arthritis 4.1% (3.8-4.3); for asthma 3.3% (2.9-3.6); and for diabetes 2.0% (1.8-2.2). An average of between 9.3% and 23.0% of participants with one or more chronic physical disease had comorbid depression. This result was significantly higher than the likelihood of having depression in the absence of a chronic physical disease (p<0.0001). After adjustment for socioeconomic factors and health conditions, depression had the largest effect on worsening mean health scores compared with the other chronic conditions. Consistently across countries and different demographic characteristics, respondents with depression comorbid with one or more chronic diseases had the worst health scores of all the disease states. INTERPRETATION: Depression produces the greatest decrement in health compared with the chronic diseases angina, arthritis, asthma, and diabetes. The comorbid state of depression incrementally worsens health compared with depression alone, with any of the chronic diseases alone, and with any combination of chronic diseases without depression. These results indicate the urgency of addressing depression as a public-health priority to reduce disease burden and disability, and to improve the overall health of populations.
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| Human Immunodeficiency Virus (HIV) Treatment With Antiretroviral Therapy Mitigates the High Risk of Mental Health Disorders Associated With HIV Infection in the US Population. | Ba DM et al. | β | 2023 | β |
| Identifying the Bridge Between Anxiety Response to COVID-19 and Depression Symptoms in General Population: A Network Analysis. | Cha EJ et al. | β | 2023 | β |
| Impact of nonalcoholic fatty liver disease-related metabolic state on depression. | Ntona S et al. | β | 2023 | β |
| Improving integrated depression and non-communicable disease care in Malawi through engaged leadership and supportive implementation climate. | Sansbury GM et al. | β | 2023 | β |
| Individual and community experiences and the use of language in understanding diabetes and depression in rural Kenya. | Lloyd CE et al. | β | 2023 | β |
| Insular-associated causal network of structural covariance evaluating progressive gray matter changes in major depressive disorder. | Lu F et al. | β | 2023 | β |
| Intestinal activating transcription factor 4 regulates stress-related behavioral alterations via paraventricular thalamus in male mice. | Yuan F et al. | β | 2023 | β |
| Is the combination of depression symptoms and multimorbidity associated with the increase of the prevalence of functional disabilities in Brazilian older adults? A cross-sectional study. | da Rosa PPS et al. | β | 2023 | β |
| Ketamine's rapid antidepressant effects are mediated by Ca<sup>2+</sup>-permeable AMPA receptors. | Zaytseva A et al. | β | 2023 | β |
| Longitudinal Trajectories of Depressive Symptoms Among Patients With Knee Osteoarthritis: The Role of Pain Intensity. | Yan Z et al. | β | 2023 | β |
| Long-term Effects of a Collaborative Care Model on Metabolic Outcomes and Depressive Symptoms: 36-Month Outcomes from the INDEPENDENT Intervention. | Suvada K et al. | β | 2023 | β |
| Long-term life satisfaction in ageing women with work disability due to mental and musculoskeletal disorders. | Heikkinen J et al. | β | 2023 | β |
| Mendelian randomization study on the causal effects of systemic lupus erythematosus on major depressive disorder. | Li W et al. | β | 2023 | β |
| Mental health challenges and digital platform opportunities in patients and families affected by pediatric neuromuscular diseases - experiences from Switzerland. | Gruebner O et al. | β | 2023 | β |
| Mental health conditions in people affected by filarial lymphoedema in Malawi: prevalence, associated risk factors and the impact of an enhanced self-care intervention. | Barrett C et al. | β | 2023 | β |
| Milk kefir drink may not reduce depression in patients with non-alcoholic fatty liver disease: secondary outcome analysis of a randomized, single-blinded, controlled clinical trial. | Mohsenpour MA et al. | β | 2023 | β |
| Morning salivary dehydroepiandrosterone (DHEA) qualifies as the only neuroendocrine biomarker separating depressed patients with and without prior history of depression: An HPA axis challenge study. | Agorastos A et al. | β | 2023 | β |
| Neighborhood Effect on Elderly Depression in Republic of Korea. | Hwang JH et al. | β | 2023 | β |
| Objective and Subjective Sleep Measures Are Related to Suicidal Ideation and Are Transdiagnostic Features of Major Depressive Disorder and Social Anxiety Disorder. | Klumpp H et al. | β | 2023 | β |
| "Our Job is to be so Temporary": Designing Digital Tools that Meet the Needs of Care Managers and their Patients with Mental Health Concerns. | Kornfield R et al. | β | 2023 | β |
| People with Diabetes Have Poorer Self-Rated Health (SRH) and Diabetes Moderates the Association between Age and SRH. | Kang W et al. | β | 2023 | β |
| Physical multimorbidity, suicidal ideation, and suicide attempts among adults aged β₯50Β years from low- and middle-income countries. | Smith L et al. | β | 2023 | β |
| Point prevalence and sex-specific associated factors of depression in Latvian general population. | Vinogradova VV et al. | β | 2023 | β |
| Predictors of residual low back pain in patients with osteoporotic vertebral fractures following percutaneous kyphoplasty. | Yu H et al. | β | 2023 | β |
| Prevalence and determinants of depression among patients with Type 2 diabetes mellitus attending family medicine clinics in Qatar. | Ismail M et al. | β | 2023 | β |
| Prevalence and risk factors of depressive symptoms in children and adolescents with juvenile idiopathic arthritis. | Roemer J et al. | β | 2023 | β |
| Prevalence of depression and anxiety in older people in low- and middle- income countries in Africa, Asia and South America: A systematic review and meta-analysis. | Edwards N et al. | β | 2023 | β |
| Prevalence of depression and association with all-cause and cardiovascular mortality among individuals with type 2 diabetes: a cohort study based on NHANES 2005-2018 data. | Feng Z et al. | β | 2023 | β |
| Prevalence of depression, anxiety and suicidal ideas and associated factors, in particular sensory impairments, in a population of Bashkortostan in Russia. | Bikbov MM et al. | β | 2023 | β |
| Primary care patients' experiences of video consultations for depression and anxiety: a qualitative interview study embedded in a randomized feasibility trial. | Haun MW et al. | β | 2023 | β |
| Primary care utilisation, adherence to guideline-based pharmacotherapy and continuity of care in primary care patients with chronic diseases and multimorbidity - a cross-sectional study. | Maun A et al. | β | 2023 | β |
| Psychiatric Illnesses, Somatic Complaints, and Treatments in a Tertiary Care Hospital in Khyber Pakhtunkhwa, Pakistan: A Cross-Sectional Study. | Wazir MNK et al. | β | 2023 | β |
| Psychological benefits of the COVID-19 vaccination: A Bangladeshi comparative study. | Nur MI et al. | β | 2023 | β |
| Psychological Determinants of Vaccination Readiness against COVID-19 and Seasonal Influenza of the Chronically Ill in Primary Care in Germany-A Cross-Sectional Survey. | Sanftenberg L et al. | β | 2023 | β |
| Psychological factors associated with instrumental activities of daily living disability in older adults with moderate to severe knee osteoarthritis. | Nanjo K et al. | β | 2023 | β |
| Psychotherapy for comorbid depression and somatic disorders: a systematic review and meta-analysis. | Miguel C et al. | β | 2023 | β |
| Quantification of the Effect of Vitamin E Intake on Depressive Symptoms in United States Adults Using Restricted Cubic Splines. | Huang AA et al. | β | 2023 | β |
| Reduced social risk-taking in depression. | Follett D et al. | β | 2023 | β |
| Relationship between Mediterranean diet and depression in South Korea: the Korea National Health and Nutrition Examination Survey. | Hwang YG et al. | β | 2023 | β |
| Reliability and aspects of validity of the Swedish version of self-efficacy for exercise scale for patients with chronic pain. | DahlbΓ€ck A et al. | β | 2023 | β |
| RNA methylations in depression, from pathological mechanism to therapeutic potential. | Li C et al. | β | 2023 | β |
| Role of BDNF-TrkB signaling in the antidepressant-like actions of loganin, the main active compound of Corni Fructus. | Gong M et al. | β | 2023 | β |
| Rural-Urban disparities in self-reported physical/mental multimorbidity: A cross-sectional study of self-reported mental health and physical health among working age adults in the U.S. | Rhubart D et al. | β | 2023 | β |
| Screening and identification of key biomarkers of depression using bioinformatics. | Kong X et al. | β | 2023 | β |
| Self-reported perceived stress, depression, and generalized anxiety disorder among Kathak dancers and physically active non-dancers of North India. | Kulshreshtha M et al. | β | 2023 | β |
| Sertraline versus escitalopram in South Asians with moderate to severe major depressive disorder: (SOUTH-DEP) a double-blind, parallel, randomized controlled trial. | Raza S et al. | β | 2023 | β |
| Severity and Factors Associated with Depressive Symptoms Among Type 2 Diabetic Patients in Vietnam. | Nguyen KT et al. | β | 2023 | β |
| Single-Nucleotide Polymorphisms in Genes Maintaining the Stability of Mitochondrial DNA Affect the Occurrence, Onset, Severity and Treatment of Major Depressive Disorder. | Czarny P et al. | β | 2023 | β |
| Strengthening integrated depression services within routine primary health care using the RE-AIM framework in South Africa. | Petersen I et al. | β | 2023 | β |
| Successful ingredients of effective Collaborative Care programs in low- and middle-income countries: A rapid review. | Whitfield J et al. | β | 2023 | β |
| The amygdala connectivity with depression and suicide ideation with suicide behavior: A meta-analysis of structural MRI, resting-state fMRI and task fMRI. | Nawaz H et al. | β | 2023 | β |
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| The Association of a Geographically Wide Social Media Network on Depression: County-Level Ecological Analysis. | Beauchamp AM et al. | β | 2023 | β |
| The association of vitamin D deficiency, age and depression in US adults: a cross-sectional analysis. | Mo H et al. | β | 2023 | β |
| The effective on intradermal acupuncture based on changes in biological specificity of acupoints for major depressive disorder: study protocol of a prospective, multicenter, randomized, controlled trial. | Tu M et al. | β | 2023 | β |
| The effects of a magic-based intervention on self-esteem, depressive symptoms, and quality of life among community-dwelling older adults: a randomised controlled trial. | Wang WL et al. | β | 2023 | β |
| The feasibility of a Community Mental Health Education and Detection (CMED) tool in South Africa. | Grant M et al. | β | 2023 | β |
| The genetic basis of major depressive disorder. | Flint J | β | 2023 | β |
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| The relationship between fatigue, sleep quality, resilience, and the risk of postpartum depression: an emphasis on maternal mental health. | Baattaiah BA et al. | β | 2023 | β |
| The Relationship between Job Satisfaction and Depressive Symptoms among Chinese Adults Aged 35-60 Years: The Mediating Role of Subjective Well-Being and Life Satisfaction. | Liu Y et al. | β | 2023 | β |
| To be happy and behave in a healthier way. A longitudinal study about gender differences in the older population. | MartΓn-MarΓa N et al. | β | 2023 | β |
| Transparency and completeness of reporting of depression screening tool accuracy studies: A meta-research review of adherence to the Standards for Reporting of Diagnostic Accuracy Studies statement. | Nassar EL et al. | β | 2023 | β |
| Treatable traits and challenges in the clinical management of non-tuberculous mycobacteria lung disease in people with cystic fibrosis. | Gramegna A et al. | β | 2023 | β |
| Treating depression in clinical practice: new insights on the multidisciplinary use of trazodone. | Albert U et al. | β | 2023 | β |
| Understanding health behavior change by motivation and reward mechanisms: a review of the literature. | Michaelsen MM et al. | β | 2023 | β |
| Understanding Mental Health Status of Syrian Refugee and Jordanian Women: Novel Insights from a Comparative Study. | Atrooz F et al. | β | 2023 | β |
| Understanding the impacts of the COVID-19 pandemic on the care experiences of people with mental-physical multimorbidity: protocol for a mixed methods study. | Menear M et al. | β | 2023 | β |
| Unrecognised depression among older people: a cross-sectional study from Norwegian general practice. | Kvalbein-Olsen LC et al. | β | 2023 | β |
| Web-Based Self-Compassion Training to Improve the Well-Being of Youth With Chronic Medical Conditions: Randomized Controlled Trial. | Finlay-Jones AL et al. | β | 2023 | β |
| We need to talk: The urgent conversation on chronic pain, mental health, prescribing patterns and the opioid crisis. | Battaglia M et al. | β | 2023 | β |
| A Chronic Inflammatory Inductive Condition in the Nursing Profession: A Scoping Review. | Vitale E | β | 2022 | β |
| A collaborative care package for depression comorbid with chronic physical conditions in South Africa. | Petersen I et al. | β | 2022 | β |
| A Concept Analysis of Illness Intrusiveness in Chronic Disease: Application of the Hybrid Model Method. | Do Y et al. | β | 2022 | β |
| ACO Participation Associated With Decreased Spending For Medicare Beneficiaries With Serious Mental Illness. | Figueroa JF et al. | β | 2022 | β |
| Ageing workers' mental health during COVID-19: a multilevel observational study on the association with the work environment, perceived workplace safety and individual factors. | Rinsky-Halivni L et al. | β | 2022 | β |
| Agomelatine Changed the Expression and Methylation Status of Inflammatory Genes in Blood and Brain Structures of Male Wistar Rats after Chronic Mild Stress Procedure. | Bialek K et al. | β | 2022 | β |
| A history of depression in patients attending a chronic pain management clinic in South Africa: A retrospective chart review. | van Vreede JJ et al. | β | 2022 | β |
| Air pollution and individuals' mental well-being in the adult population in United Kingdom: A spatial-temporal longitudinal study and the moderating effect of ethnicity. | Abed Al Ahad M et al. | β | 2022 | β |
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| A methodological note on the CYP-guides randomized controlled trial for the treatment of major depression. | Sideridis G et al. | β | 2022 | β |
| Anxiety/Depression Predominance in Liaison-Psychiatry Users of a South-East Mexico Tertiary Hospital. | GΓ³mez-de-Regil L et al. | β | 2022 | β |
| Anxiety Screening among the General Population of Latvia and Associated Factors. | Vinogradova VV et al. | β | 2022 | β |
| Are cancer patients with high depressive symptom levels able to manage these symptoms without professional care? The role of coping and social support. | Bickel EA et al. | β | 2022 | β |
| Are non-face-to-face interactions an effective strategy for maintaining mental and physical health? | Katayama O et al. | β | 2022 | β |
| Association between Agility, Health-Related Quality of Life, Depression, and Anthropometric Variables in Physically Active Older Adult Women with Depression. | GalΓ‘n-Arroyo C et al. | β | 2022 | β |
| Association between chronic physical conditions and depressive symptoms among hospital workers in a national medical institution designated for COVID-19 in Japan. | Fukunaga A et al. | β | 2022 | β |
| Association between the CLOCK gene polymorphism and depressive symptom mediated by sleep quality among non-clinical Chinese Han population. | Li Y et al. | β | 2022 | β |
| Association between the domestic use of solid cooking fuel and increased prevalence of depression and cognitive impairment in a big developing country: A large-scale population-based study. | Jin Y et al. | β | 2022 | β |
| Association of longitudinal changes in quality of life with comorbidities and exacerbations in patients with severe asthma. | Matsumoto-Sasaki M et al. | β | 2022 | β |
| Associations Between Consumption of Different Vegetable Types and Depressive Symptoms in Japanese Workers: A Cross-Sectional Study. | Gong Q et al. | β | 2022 | β |
| Associations between depression and cognition, mild cognitive impairment and dementia in persons with diabetes mellitus: A systematic review and meta-analysis. | Chow YY et al. | β | 2022 | β |
| Associations of Antidepressants With Atrial Fibrillation and Ventricular Arrhythmias: A Systematic Review and Meta-Analysis. | Cao Y et al. | β | 2022 | β |
| Associations of self-reported vision impairment with depression symptoms among middle-aged and older Chinese. | Yang Y et al. | β | 2022 | β |
| A systematic review of the rates of depression in autistic children and adolescents without intellectual disability. | Stewart TM et al. | β | 2022 | β |
| Behavioral alterations, brain oxidative stress, and elevated levels of corticosterone associated with a pressure injury model in male mice. | Aquino GA et al. | β | 2022 | β |
| Botany, traditional uses, phytochemistry and pharmacological activity of Crataegus pinnatifida (Chinese hawthorn): a review. | Zhang SY et al. | β | 2022 | β |
| Building Emotional Awareness and Mental Health (BEAM): study protocol for a phase III randomized controlled trial of the BEAM app-based program for mothers of children 18-36 months. | Xie EB et al. | β | 2022 | β |
| Burden of mental distress in the United States is associated with delayed medical visits and missed prescription refills during the COVID-19 pandemic. | Jalan M et al. | β | 2022 | β |
| C1q deletion exacerbates stress-induced learned helplessness behavior and induces neuroinflammation in mice. | Madeshiya AK et al. | β | 2022 | β |
| Chronic disease and depression among the elderly in China: the mediating role of instrumental activities of daily living and the moderating role of area of residence. | Yuan J et al. | β | 2022 | β |
| Chronic inflammation as a potential mediator between phthalate exposure and depressive symptoms. | Bao C et al. | β | 2022 | β |
| Combinational Regularity Analysis (CORA) - a new method for uncovering complex causation in medical and health research. | Thiem A et al. | β | 2022 | β |
| Combined HTR1A/1B methylation and human functional connectome to recognize patients with MDD. | Xu Z et al. | β | 2022 | β |
| Combined repetitive transcranial magnetic stimulation and medication treatment for depression is associated with serum amyloid a level: Evidence from naturalistic clinical practice. | Xu Y et al. | β | 2022 | β |
| Comorbidity of mental and musculoskeletal disorders in ageing women: A data linkage study using national registries. | Heikkinen J et al. | β | 2022 | β |
| Comparison of the Center for Epidemiologic Studies Depression Scale and other tools to screen depression in patients with chronic disease. | Park SH | β | 2022 | β |
| Constituents of fine particulate matter and asthma in 6 low- and middle-income countries. | Wang X et al. | β | 2022 | β |
| Cross-Sectional Associations between Living and Built Environments and Depression Symptoms among Chinese Older Adults. | Hou F et al. | β | 2022 | β |
| Cross sectional study of depression, anxiety and quality of life in glaucoma patients at a tertiary centre in North Kerala. | Ajith BS et al. | β | 2022 | β |
| Decreased modular segregation of the frontal-parietal network in major depressive disorder. | Lan Z et al. | β | 2022 | β |
| Depression and food insecurity among patients with rheumatoid arthritis in NHANES. | Cai Q et al. | β | 2022 | β |
| Depression, Anxiety, Perceived Stress and Family Support in COVID-19 Patients. | Hosseini Largani M et al. | β | 2022 | β |
| Depression compromises antiviral innate immunity via the AVP-AHI1-Tyk2 axis. | Zhang HG et al. | β | 2022 | β |
| Depression in Urban Omani Adults with Type 2 Diabetes: A cross-sectional study. | Alsumry SH et al. | β | 2022 | β |
| Depression symptoms, HIV testing, linkage to ART, and viral suppression among women in a high HIV burden district in KwaZulu-Natal, South Africa: A cross-sectional household study. | Govender K et al. | β | 2022 | β |
| Depressive Symptoms and Suicidal Thoughts in Restless Legs Syndrome. | Chenini S et al. | β | 2022 | β |
| Design Strategies, Chemistry and Therapeutic Insights of Multi-target Directed Ligands as Antidepressant Agents. | Singh K et al. | β | 2022 | β |
| Design, Synthesis, and Biological Activity of Chalcone Analogs Containing 4-Phenylquinolin and Benzohydrazide. | Tan QW et al. | β | 2022 | β |
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| Determining the association between different living arrangements and depressive symptoms among over-65-year-old people: The moderating role of outdoor activities. | Xu R et al. | β | 2022 | β |
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| Dietary Zinc Intake Affects the Association Between Dietary Vitamin A and Depression: A Cross-Sectional Study. | Hu B et al. | β | 2022 | β |
| Differential effects of lipopolysaccharide on cognition, corticosterone and cytokines in socially-housed vs isolated male rats. | Russell B et al. | β | 2022 | β |
| Digital and Mobile Health Technology in Collaborative Behavioral Health Care: Scoping Review. | Moon K et al. | β | 2022 | β |
| Digital Health Interventions for Depression and Anxiety Among People With Chronic Conditions: Scoping Review. | Shah A et al. | β | 2022 | β |
| Do Recent Experiences of Sexual Violence and Co-Occurring Depression and Anxiety Symptoms Predict Poorer Functioning One Year Later During the Transition to Young Adulthood? | Davis JP et al. | β | 2022 | β |
| Dose effect of psilocybin on primary and secondary depression: a preliminary systematic review and meta-analysis. | Li NX et al. | β | 2022 | β |
| Drug-Associated Parosmia: New Perspectives from the WHO Safety Database. | Merino D et al. | β | 2022 | β |
| Dysfunctional Heteroreceptor Complexes as Novel Targets for the Treatment of Major Depressive and Anxiety Disorders. | PΓ©rez de la Mora M et al. | β | 2022 | β |
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| Effect of a Behavioural Intervention for Adoption and Maintenance of a Physically Active Lifestyle on Psychological Well-Being and Quality of Life in Patients with Type 2 Diabetes: The IDES_2 Randomized Clinical Trial. | Nicolucci A et al. | β | 2022 | β |
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| Evaluating effects of the structural reform of outpatient psychotherapy for patients with mental disorders in Germany: comparing patients with and without comorbid chronic physical condition - rationale and study protocol of the ES-RiP project. | Kampling H et al. | β | 2022 | β |
| Evaluation of a Stepped Care Approach to Manage Depression and Diabetes Distress in Patients with Type 1 Diabetes and Type 2 Diabetes: Results of a Randomized Controlled Trial (ECCE HOMO Study). | Schmitt A et al. | β | 2022 | β |
| Exploring the relationship between depression and different multimorbidity patterns among older people covered by long-term care insurance in Shanghai, China. | Li C et al. | β | 2022 | β |
| Food Insecurity Is Associated with Mental-Physical Comorbidities among U.S. Adults: NHANES 2013 to 2016. | O'Neal LJ et al. | β | 2022 | β |
| From Weight Bias Internalization to Health-Related Quality of Life: Self-esteem and Psychopathology in Pre-bariatric Surgery Patients. | Liu X et al. | β | 2022 | β |
| Gender Difference in Fear and Anxiety about and Perceived Susceptibility to COVID-19 in the Third Wave of Pandemic among the Japanese General Population: A Nationwide Web-Based Cross-Sectional Survey. | Sasaki R et al. | β | 2022 | β |
| Ginsenosides in central nervous system diseases: Pharmacological actions, mechanisms, and therapeutics. | Lu J et al. | β | 2022 | β |
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| Greater Social Functioning Associated With Lower Depressive Symptomatology Among Black Belt African Americans Enrolled in the Southeastern Collaboration to Improve Blood Pressure Control Study. | Finch AJ et al. | β | 2022 | β |
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| High Yielding Continuous-Flow Synthesis of Norketamine. | Hernando MV et al. | β | 2022 | β |
| Histological, immunohistochemical and radiographic evaluation of Amitriptyline administration on the periodontium of albino rats (An experimental study). | Hassan R et al. | β | 2022 | β |
| <i>Lactobacillus paracasei</i> CCFM1229 and <i>Lactobacillus rhamnosus</i> CCFM1228 Alleviated Depression- and Anxiety-Related Symptoms of Chronic Stress-Induced Depression in Mice by Regulating Xanthine Oxidase Activity in the Brain. | Xu M et al. | β | 2022 | β |
| Impact of malnutrition and frailty on mortality and major amputation in patients with CLTI. | Karim AM et al. | β | 2022 | β |
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| Intervention for Treating Depression in Parents of Children with Intellectual Disability of Down's Syndrome: A Sample of Nigerian Parents. | Ede MO et al. | β | 2022 | β |
| Investigating the impact of a chronic disease self-management programme on depression and quality of life scores in an Irish sample. | Campbell D et al. | β | 2022 | β |
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| Is there a relationship between morphological and functional platelet changes and depressive disorder? | Tagliarini C et al. | β | 2022 | β |
| "It's what makes us unique": Indigenous Australian perspectives on genetics research to improve comorbid mental and chronic disease outcomes. | Nasir BF et al. | β | 2022 | β |
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| Mind the gap: Identifying training needs of community health workers to address mental health in U.S. Latino communities during and beyond the COVID-19 pandemic. | Garcini LM et al. | β | 2022 | β |
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