Modeling Gene-Environment Interactions With Quasi-Natural Experiments.
- Authors
- Schmitz, Lauren; Conley, Dalton
- Year
- 2017
- Journal
- Journal of personality
- PMID
- 26340722
- DOI
- 10.1111/jopy.12227
This overview develops new empirical models that can effectively document Gene × Environment (G×E) interactions in observational data. Current G×E studies are often unable to support causal inference because they use endogenous measures of the environment or fail to adequately address the nonrandom distribution of genes across environments, confounding estimates. Comprehensive measures of genetic variation are incorporated into quasi-natural experimental designs to exploit exogenous environmental shocks or isolate variation in environmental exposure to avoid potential confounders. In addition, we offer insights from population genetics that improve upon extant approaches to address problems from population stratification. Together, these tools offer a powerful way forward for G×E research on the origin and development of social inequality across the life course.
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External
| Title | Authors | Journal | Year | Link |
|---|---|---|---|---|
| The Economics and Econometrics of Gene-Environment Interplay. | Biroli P et al. | — | 2026 | → |
| Neighborhood context, genetic influences, and life satisfaction: Evidence from the German twin family panel. | Harerimana NV et al. | — | 2025 | → |
| Raising the Floor? Genetic Influences on Educational Attainment Through the Lens of the Evolving Swedish Welfare State. | Pettersson O | — | 2025 | → |
| The role of gene-environment interaction in the formation of risk attitudes. | Groero J | — | 2024 | → |
| Association between genetic risk of alcohol consumption and alcohol-related morbidity and mortality under different alcohol policy conditions: Evidence from the Finnish alcohol price reduction of 2004. | Lahtinen H et al. | — | 2023 | → |
| The nature-nurture of academic achievement at the intersection between gender, family background, and school context. | Stienstra K et al. | — | 2023 | → |
| An in-laboratory stressor reveals unique genetic variation in child cortisol output. | Raffington L et al. | — | 2022 | → |
| Differential Relations of Parental Behavior to Children's Early Executive Function as a Function of Child Genotype: A Systematic Review. | Vrantsidis DM et al. | — | 2022 | → |
| From Genome-Wide to Environment-Wide: Capturing the Environome. | von Stumm S et al. | — | 2022 | → |
| How interactions between ADHD and schools affect educational achievement: a family-based genetically sensitive study. | Cheesman R et al. | — | 2022 | → |
| Schooling substantially improves intelligence, but neither lessens nor widens the impacts of socioeconomics and genetics. | Judd N et al. | — | 2022 | → |
| Gene-environment dependencies lead to collider bias in models with polygenic scores. | Akimova ET et al. | — | 2021 | → |
| "Reports of My Death Were Greatly Exaggerated": Behavior Genetics in the Postgenomic Era. | Harden KP | — | 2021 | → |
| The impact of late-career job loss and genetic risk on body mass index: Evidence from variance polygenic scores. | Schmitz LL et al. | — | 2021 | → |
| Education can reduce health differences related to genetic risk of obesity. | Barcellos SH et al. | — | 2018 | → |
| Education can Reduce Health Disparities Related to Genetic Risk of Obesity: Evidence from a British Reform | Barcellos SH et al. | — | 2018 | — |
| Post-GWAS in Psychiatric Genetics: A Developmental Perspective on the "Other" Next Steps. | Dick DM et al. | — | 2018 | → |
| The Biosocial Approach to Human Development, Behavior, and Health Across the Life Course. | Harris KM et al. | — | 2018 | → |
| The Effect of Vietnam-Era Conscription and Genetic Potential for Educational Attainment on Schooling Outcomes. | Schmitz LL et al. | — | 2017 | → |