The molecular hallmarks of epigenetic control.
paper
Cited
Public
Unavailable
- Authors
- Allis, C David; Jenuwein, Thomas
- Year
- 2016
- Journal
- Nature reviews. Genetics
- PMID
- 27346641
- DOI
- 10.1038/nrg.2016.59
Over the past 20 years, breakthrough discoveries of chromatin-modifying enzymes and associated mechanisms that alter chromatin in response to physiological or pathological signals have transformed our knowledge of epigenetics from a collection of curious biological phenomena to a functionally dissected research field. Here, we provide a personal perspective on the development of epigenetics, from its historical origins to what we define as 'the modern era of epigenetic research'. We primarily highlight key molecular mechanisms of and conceptual advances in epigenetic control that have changed our understanding of normal and perturbed development.
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| Long non-coding RNA (LncRNA) and epigenetic factors: their role in regulating the adipocytes in bovine. | Jilo DD et al. | β | 2024 | β |
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| LSD1 promotes the FSH responsive follicle formation by regulating autophagy and repressing Wt1 in the granulosa cells. | Zhu Z et al. | β | 2024 | β |
| Macromolecular Complex Including MLL3, Carabin and Calcineurin Regulates Cardiac Remodeling. | Pane R et al. | β | 2024 | β |
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| Mapping the dynamics of epigenetic adaptation in S.Β pombe during heterochromatin misregulation. | Larkin A et al. | β | 2024 | β |
| Mass spectrometry-intensive top-down proteomics: an update on technology advancements and biomedical applications. | Xu T et al. | β | 2024 | β |
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| Metabolic Recoding of NSUN2-Mediated m<sup>5</sup>C Modification Promotes the Progression of Colorectal Cancer via the NSUN2/YBX1/m<sup>5</sup>C-ENO1 Positive Feedback Loop. | Chen B et al. | β | 2024 | β |
| Methylation marks in blood DNA reveal breast cancer risk in patients fulfilling hereditary disease criteria. | Ruiz-De La Cruz M et al. | β | 2024 | β |
| Methylation of Interleukin-1 receptor-associated kinase-3 and the risk of multiple sclerosis relapse/activity. | Watany MM et al. | β | 2024 | β |
| Methyltransferase like-14 suppresses growth and metastasis of non-small-cell lung cancer by decreasing LINC02747. | Wang J et al. | β | 2024 | β |
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| Multiomics analysis reveals the potential mechanism of high-fat diet in dextran sulfate sodium-induced colitis mice model. | Zhao Y et al. | β | 2024 | β |
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| Neuroepigenetic Editing. | Hamilton PJ et al. | β | 2024 | β |
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| Nucleosome conformation dictates the histone code. | Marunde MR et al. | β | 2024 | β |
| Nutrient-epigenome interactions: Implications for personalized nutrition against aging-associated diseases. | Missong H et al. | β | 2024 | β |
| Optimized and Robust Workflow for Quantifying the Canonical Histone Ubiquitination Marks H2AK119ub and H2BK120ub by LC-MS/MS. | Lopes M et al. | β | 2024 | β |
| Optimizing Adoptive Cell Therapy for Solid Tumors via Epigenetic Regulation of T-cell Destiny. | Guo X et al. | β | 2024 | β |
| OsJMJ718, a histone demethylase gene, positively regulates seed germination in rice. | Jia J et al. | β | 2024 | β |
| Parthenocarpy, a pollination-independent fruit set mechanism to ensure yield stability. | MaupilΓ© L et al. | β | 2024 | β |
| Pathomechanistic Networks of Motor System Injury in Amyotrophic Lateral Sclerosis. | Dey B et al. | β | 2024 | β |
| Persistent in vivo epigenetic silencing of Pcsk9. | Gengaro IR et al. | β | 2024 | β |
| Pharmacological targeting of the cancer epigenome. | Mabe NW et al. | β | 2024 | β |
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| Poly (ADP-ribose) Polymerase-1 modulations in the genesis of thrombosis. | Safdar R et al. | β | 2024 | β |
| Poly(ADP-ribosyl)ation enhances nucleosome dynamics and organizes DNA damage repair components within biomolecular condensates. | Nosella ML et al. | β | 2024 | β |
| Polyphenolic Compounds: Orchestrating Intestinal Microbiota Harmony during Aging. | Pereira QC et al. | β | 2024 | β |
| Potential Early Effect Biomarkers for Ambient Air Pollution Related Mental Disorders. | Bai L et al. | β | 2024 | β |
| PRC1 directs PRC2-H3K27me3 deposition to shield adult spermatogonial stem cells from differentiation. | Hu M et al. | β | 2024 | β |
| Precision epigenetic editing: Technological advances, enduring challenges, and therapeutic applications. | Roth GV et al. | β | 2024 | β |
| Protein degradation of Lsd1 is mediated by Bre1 yet opposed by <i>Lsd1-interacting lncRNAs</i> during fly follicle development. | Lin CT et al. | β | 2024 | β |
| Recent advancements of fluorescent biosensors using semisynthetic probes. | Reja SI et al. | β | 2024 | β |
| Recent advances in sarcoma therapy: new agents, strategies and predictive biomarkers. | Pan M et al. | β | 2024 | β |
| Restoration of epigenetic impairment in the skeletal muscle and chronic inflammation resolution as a therapeutic approach in sarcopenia. | Livshits G et al. | β | 2024 | β |
| Revealing role of epigenetic modifiers and DNA oxidation in cell-autonomous regulation of Cancer stem cells. | Ferrer-Diaz AI et al. | β | 2024 | β |
| Reversal of T-cell exhaustion: Mechanisms and synergistic approaches. | Hu Y et al. | β | 2024 | β |
| Reversible Histone Modifications Contribute to the Frozen and Thawed Recovery States of Wood Frog Brains. | Bloskie T et al. | β | 2024 | β |
| Rice responds to Spodoptera frugiperda infestation via epigenetic regulation of H3K9ac in the jasmonic acid signaling and phenylpropanoid biosynthesis pathways. | Xue R et al. | β | 2024 | β |
| Role of epigenetic mechanisms in the pathogenesis of chronic respiratory diseases and response to inhaled exposures: From basic concepts to clinical applications. | Jurkowska RZ | β | 2024 | β |
| Role of H3K4 monomethylation in gene regulation. | Wang Z et al. | β | 2024 | β |
| Role of Serotonylation and SERT Posttranslational Modifications in Alzheimer's Disease Pathogenesis. | Reddy AP et al. | β | 2024 | β |
| RUNX1-IT1 acts as a scaffold of STAT1 and NuRD complex to promote ROS-mediated NF-ΞΊB activation and ovarian cancer progression. | Yu X et al. | β | 2024 | β |
| scDMV: a zero-one inflated beta mixture model for DNA methylation variability with scBS-seq data. | Zhou Y et al. | β | 2024 | β |
| Sex and Gender in Ageing and Longevity: Highlights From an International Course. | Candore G et al. | β | 2024 | β |
| Solving the Global Opioid Crisis: Incorporating Genetic Addiction Risk Assessment with Personalized Dopaminergic Homeostatic Therapy and Awareness Integration Therapy. | Zeine F et al. | β | 2024 | β |
| Spatial covariation between genetic and epigenetic diversity in wild plant and animal populations: a meta-analysis. | Langford N et al. | β | 2024 | β |
| Spermidine as an epigenetic regulator of autophagy in neurodegenerative disorders. | Satarker S et al. | β | 2024 | β |
| Splicing junction-based classifier for the detection of abnormal constitutive activation of the KEAP1-NRF2 system. | Mateos RN et al. | β | 2024 | β |
| Stiffness assisted cell-matrix remodeling trigger 3D mechanotransduction regulatory programs. | Kersey AL et al. | β | 2024 | β |
| Structure of the human TIP60-C histone exchange and acetyltransferase complex. | Li C et al. | β | 2024 | β |
| Tackling triple negative breast cancer with HDAC inhibitors: 6 is the isoform! | Guadagni A et al. | β | 2024 | β |
| Targeting DNA Methylation Machinery in Pediatric Solid Tumors. | Cristalli C et al. | β | 2024 | β |
| Targeting epigenetic dysregulation in autism spectrum disorders. | Herrera ML et al. | β | 2024 | β |
| Targeting 'histone mark': Advanced approaches in epigenetic regulation of telomere dynamics in cancer. | Das A et al. | β | 2024 | β |
| Targeting histone modifiers in bladder cancer therapy - preclinical and clinical evidence. | Zhang S et al. | β | 2024 | β |
| T cell exhaustion in human cancers. | Kang K et al. | β | 2024 | β |
| TGF-Ξ² and RAS jointly unmask primed enhancers to drive metastasis. | Lee JH et al. | β | 2024 | β |
| The alarming link between environmental microplastics and health hazards with special emphasis on cancer. | Goswami S et al. | β | 2024 | β |
| The Causes for Genomic Instability and How to Try and Reduce Them Through Rational Design of Synthetic DNA. | Arbel-Groissman M et al. | β | 2024 | β |
| The effect of circulating tumor DNA on the prognosis of patients with head and neck squamous cell carcinoma: a systematic review and meta-analysis. | Yang R et al. | β | 2024 | β |
| The emerging role of the gut microbiome in cancer cell plasticity and therapeutic resistance. | Mondal P et al. | β | 2024 | β |
| The epigenome under pressure: On regulatory adaptation to chronic stress in the brain. | Arzate-Mejia RG et al. | β | 2024 | β |
| The histone deacetylase inhibitor MS-275 enhances the matrix mineralization of dental pulp stem cells by inducing fibronectin expression. | Suzuki S et al. | β | 2024 | β |
| The Impact of Alcohol-Induced Epigenetic Modifications in the Treatment of Alcohol use Disorders. | Fanfarillo F et al. | β | 2024 | β |
| The impact of chromatin on double-strand break repair: Imaging tools and discoveries. | van Bueren MAE et al. | β | 2024 | β |
| The m6A Reader YTHDC2 Suppresses Lung Adenocarcinoma Tumorigenesis by Destabilizing MRPL12. | Sun Y et al. | β | 2024 | β |
| The molecular basis of cell memory in mammals: The epigenetic cycle. | Espinosa-MartΓnez M et al. | β | 2024 | β |
| The Molecular Basis of Differentiation Wave Activity in Embryogenesis. | Alicea B et al. | β | 2024 | β |
| The neuropsychopharmacology of acetyl-L-carnitine (LAC): basic, translational and therapeutic implications. | Bigio B et al. | β | 2024 | β |
| The novel mechanism facilitating chronic hepatitis B infection: immunometabolism and epigenetic modification reprogramming. | Wang Z et al. | β | 2024 | β |
| The role of chromatin modulator DPY30 in glucose metabolism of colorectal cancer cells. | Mao X et al. | β | 2024 | β |
| The role of epigenetics in insects in changing environments. | Du J et al. | β | 2024 | β |
| The role of m<sup>6</sup>A RNA methylation in autoimmune diseases: Novel therapeutic opportunities. | Shan Y et al. | β | 2024 | β |
| The role of the methyltransferase METTL3 in prostate cancer: a potential therapeutic target. | Zhou X et al. | β | 2024 | β |
| The roles of epigenetic regulation in graft-versus-host disease. | Wang Y et al. | β | 2024 | β |
| The TERT Promoter is Polycomb-Repressed in Neuroblastoma Cells with Long Telomeres. | Graham MK et al. | β | 2024 | β |
| TIANA: transcription factors cooperativity inference analysis with neural attention. | Li RZ et al. | β | 2024 | β |
| Tissue engineering approaches for dental pulp regeneration: The development of novel bioactive materials using pharmacological epigenetic inhibitors. | Quigley RM et al. | β | 2024 | β |
| To Erase or Not to Erase: Non-Canonical Catalytic Functions and Non-Catalytic Functions of Members of Histone Lysine Demethylase Families. | Di Nisio E et al. | β | 2024 | β |
| Tracking live-cell single-molecule dynamics enables measurements of heterochromatin-associated protein-protein interactions. | Chen Z et al. | β | 2024 | β |
| Transcriptional reprogramming post-peripheral nerve injury: A systematic review. | Hayward R et al. | β | 2024 | β |
| Transcriptome analysis in various cell lines exposed to nitric oxide. | Mizushima T et al. | β | 2024 | β |
| Transgenerational epigenetic heritability for growth, body composition, and reproductive traits in Landrace pigs. | Araujo AC et al. | β | 2024 | β |
| Uncovering the Embryonic Origins of Duchenne Muscular Dystrophy. | Barrett P et al. | β | 2024 | β |
| Unlocking epigenetic breeding potential in tomato and potato. | Zhang P et al. | β | 2024 | β |
| Using synthetic genome readers/regulators to interrogate chromatin processes: A brief review. | Philips SJ et al. | β | 2024 | β |
| Vacuolar H<sup>+</sup>-ATPase determines daughter cell fates through asymmetric segregation of the nucleosome remodeling and deacetylase complex. | Xie Z et al. | β | 2024 | β |
| Versatile JMJD proteins: juggling histones and much more. | Oh S et al. | β | 2024 | β |
| Ξ²-Aminobutyric acid promotes stress tolerance, physiological adjustments, as well as broad epigenetic changes at DNA and RNA nucleobases in field elms (Ulmus minor). | Hoenicka H et al. | β | 2024 | β |
| Acetyl-methyllysine marks chromatin at active transcription start sites. | Lu-Culligan WJ et al. | β | 2023 | β |
| A DNA Methylation Perspective on Infertility. | Shacfe G et al. | β | 2023 | β |
| Advances in Understanding and Treating Amyotrophic Lateral Sclerosis (ALS): A Comprehensive Review. | Gupta D et al. | β | 2023 | β |
| A Glimpse into Chromatin Organization and Nuclear Lamina Contribution in Neuronal Differentiation. | Martino S et al. | β | 2023 | β |
| A Kuhnian revolution in molecular biology: Most genes in complex organisms express regulatory RNAs. | Mattick JS | β | 2023 | β |
| Analysis approaches for the identification and prediction of <i>N</i><sup>6</sup>-methyladenosine sites. | Yang Y et al. | β | 2023 | β |
| Analysis of Chromatin Accessibility and DNA Methylation to Reveal the Functions of Epigenetic Modifications in <i>Cyprinus carpio</i> Gonads. | Hou M et al. | β | 2023 | β |
| Analysis of m<sup>6</sup>A methylation patterns and tumor microenvironment in endometrial cancer. | Chen J et al. | β | 2023 | β |
| An Analysis of JADE2 in Non-Small Cell Lung Cancer (NSCLC). | Murphy C et al. | β | 2023 | β |
| A quantum physics layer of epigenetics: a hypothesis deduced from charge transfer and chirality-induced spin selectivity of DNA. | Siebert R et al. | β | 2023 | β |
| Associations between nutrients in one-carbon metabolism and fetal DNA methylation in pregnancies with or without gestational diabetes mellitus. | Kadam I et al. | β | 2023 | β |
| Balance between autophagy and cell death is maintained by Polycomb-mediated regulation during stem cell differentiation. | Puri D et al. | β | 2023 | β |
| Biological Embedding of Early-Life Adversity and a Scoping Review of the Evidence for Intergenerational Epigenetic Transmission of Stress and Trauma in Humans. | Zhou A et al. | β | 2023 | β |
| Biological mechanisms matter in contemporary wildlife conservation. | Cooke SJ et al. | β | 2023 | β |
| By what molecular mechanisms do social determinants impact cardiometabolic risk? | Baumer Y et al. | β | 2023 | β |
| Cardiac Fibrosis in heart failure: Focus on non-invasive diagnosis and emerging therapeutic strategies. | Ravassa S et al. | β | 2023 | β |
| Carving Non-Proximal Explanations for Same-Sex Sexual Orientation. | Raymond M et al. | β | 2023 | β |
| Characteristics of elderly diabetes patients: focus on clinical manifestation, pathogenic mechanism, and the role of traditional Chinese medicine. | Yang X et al. | β | 2023 | β |
| Characterization of chromatin accessibility patterns in different mouse cell types using machine learning methods at single-cell resolution. | Xu Y et al. | β | 2023 | β |
| Characterization of molecular mechanisms driving Merkel cell polyomavirus oncogene transcription and tumorigenic potential. | Yang JF et al. | β | 2023 | β |
| Characterizing cis-regulatory elements using single-cell epigenomics. | Preissl S et al. | β | 2023 | β |
| Chemical Inhibitors Targeting the Histone Lysine Demethylase Families with Potential for Drug Discovery. | Das ND et al. | β | 2023 | β |
| Chromatin accessibility, not 5mC methylation covaries with partial dosage compensation in crows. | CatalΓ‘n A et al. | β | 2023 | β |
| Chromatin complex dependencies reveal targeting opportunities in leukemia. | Najm FJ et al. | β | 2023 | β |
| Chromatin regulation of transcriptional enhancers and cell fate by the Sotos syndrome gene NSD1. | Sun Z et al. | β | 2023 | β |
| c-Jun N-Terminal Kinase Promotes Stress Granule Assembly and Neurodegeneration in C9orf72-Mediated ALS and FTD. | Sahana TG et al. | β | 2023 | β |
| Comparative three-dimensional genome architectures of adipose tissues provide insight into human-specific regulation of metabolic homeostasis. | Liu P et al. | β | 2023 | β |
| Context-defined cancer co-dependency mapping identifies a functional interplay between PRC2 and MLL-MEN1 complex in lymphoma. | Chen X et al. | β | 2023 | β |
| Context-Dependent Functions of KDM6 Lysine Demethylases in Physiology and Disease. | Tayari MM et al. | β | 2023 | β |
| Coordination of RNA modifications in the brain and beyond. | Chen AY et al. | β | 2023 | β |
| Correlation of DNA methylation and lymph node metastasis in papillary thyroid carcinoma. | Zhao F et al. | β | 2023 | β |
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| Current technical advancements in plant epitranscriptomic studies. | Xie Y et al. | β | 2023 | β |
| DeΒ novo induction of a DNA-histone H3K9 methylation loop on synthetic human repetitive DNA in cultured tobacco cells. | Otake K et al. | β | 2023 | β |
| Depositing centromere repeats induces heritable intragenic heterochromatin establishment and spreading in Arabidopsis. | Liu ZW et al. | β | 2023 | β |
| Detection of DNA Modification Using Nanopore Sequencers. | Furuta Y | β | 2023 | β |
| Development of Chromatin Immunoprecipitation for the Analysis of Histone Modifications in Red Macroalga Neopyropia yezoensis (Rhodophyta). | Ueda S et al. | β | 2023 | β |
| Development of homozygous tetraploid potato and whole genome doubling-induced the enrichment of H3K27ac and potentially enhanced resistance to cold-induced sweetening in tubers. | Guo H et al. | β | 2023 | β |
| Development of super-specific epigenome editing by targeted allele-specific DNA methylation | Rajaram N et al. | β | 2023 | β |
| Development of super-specific epigenome editing by targeted allele-specific DNA methylation. | Rajaram N et al. | β | 2023 | β |
| Diet as an epigenetic factor in inflammatory bowel disease. | Marangoni K et al. | β | 2023 | β |
| Differentiated oxidation modes of guanine between CpG and <sup>5m</sup>CpG by a photoactivatable Pt(IV) anticancer prodrug. | Ma Z et al. | β | 2023 | β |
| Direct Lineage Reprogramming for Induced Keratinocyte Stem Cells: A Potential Approach for Skin Repair. | Lin H et al. | β | 2023 | β |
| DNA methylation changes from primary cultures through senescence-bypass in Syrian hamster fetal cells initially exposed to benzo[a]pyrene. | Desaulniers D et al. | β | 2023 | β |
| DNA methylation changes underlie the long-term association between periodontitis and atherosclerotic cardiovascular disease. | Omar M et al. | β | 2023 | β |
| DNA methylation variations and epigenetic aging in telomere biology disorders. | Carlund O et al. | β | 2023 | β |
| DNA Repair Inhibitors: Potential Targets and Partners for Targeted Radionuclide Therapy. | Obata H et al. | β | 2023 | β |
| Drug-induced loss of imprinting revealed using bioluminescent reporters of Cdkn1c. | Dimond A et al. | β | 2023 | β |
| Dysregulation of histone modifications in bone marrow mesenchymal stem cells during skeletal ageing: roles and therapeutic prospects. | Li Y et al. | β | 2023 | β |
| Enhancing Our Understanding of Cell Types, Differentiation, and Disease Through Enhancers: An Interview with CΓ©sar Daniel MelΓ©ndez-RamΓrez, MS. | Abu-Shamma R | β | 2023 | β |
| EpiCompare: R package for the comparison and quality control of epigenomic peak files. | Choi S et al. | β | 2023 | β |
| Epidrugs in the Therapy of Central Nervous System Disorders: A Way to Drive on? | Gladkova MG et al. | β | 2023 | β |
| Epigenetic aging of mammalian gametes. | Klutstein M et al. | β | 2023 | β |
| Epigenetic Changes Occurring in Plant Inbreeding. | Achrem M et al. | β | 2023 | β |
| Epigenetic Cooperativity as a Therapeutic Vulnerability in Cancer. | Kazansky Y et al. | β | 2023 | β |
| Epigenetic CpG duplex marks probed by an evolved DNA reader via a well-tempered conformational plasticity. | Singh H et al. | β | 2023 | β |
| Epigenetic (De)regulation in Prostate Cancer. | Xu C et al. | β | 2023 | β |
| Epigenetic effects of short-chain fatty acids from the large intestine on host cells. | Stein RA et al. | β | 2023 | β |
| Epigenetic function during heroin self-administration controls future relapse-associated behavior in a cell type-specific manner. | Anderson EM et al. | β | 2023 | β |
| Epigenetic markers in the embryonal germ cell development and spermatogenesis. | Odroniec A et al. | β | 2023 | β |
| Epigenetic mechanisms to propagate histone acetylation by p300/CBP. | Kikuchi M et al. | β | 2023 | β |
| Epigenetic moonlighting: Catalytic-independent functions of histone modifiers in regulating transcription. | Morgan MAJ et al. | β | 2023 | β |
| Epigenetic regulation in lung cancer. | Ramazi S et al. | β | 2023 | β |
| Epigenetic Regulation of Angiogenesis in Peripheral Artery Disease. | Malhi NK et al. | β | 2023 | β |
| Epigenetic regulation of photoperiodic flowering in plants. | Liu S et al. | β | 2023 | β |
| Epigenetic regulation of pyroptosis in cancer: Molecular pathogenesis and targeting strategies. | Zhang RN et al. | β | 2023 | β |
| Epigenetics as a Therapeutic Target in Osteoarthritis. | NΓΊΓ±ez-Carro C et al. | β | 2023 | β |
| Epigenetics as a versatile regulator of fibrosis. | Liu Y et al. | β | 2023 | β |
| Epigenetics in psychiatry: Beyond DNA methylation. | Kouter K et al. | β | 2023 | β |
| Epigenetic therapeutics in dental pulp treatment: Hopes, challenges and concerns for the development of next-generation biomaterials. | Duncan HF et al. | β | 2023 | β |
| Epigenomic reprogramming in iAs-mediated carcinogenesis. | George S et al. | β | 2023 | β |
| Essential role of bromodomain proteins in renal cell carcinoma (Review). | Wen Q et al. | β | 2023 | β |
| Exosomes: A Promising Strategy for Repair, Regeneration and Treatment of Skin Disorders. | Tienda-VΓ‘zquez MA et al. | β | 2023 | β |
| Gender disparities in clinical outcomes of urothelial carcinoma linked to X chromosome gene <i>KDM6A</i> mutation. | Liu Z et al. | β | 2023 | β |
| Gene and schizophrenia in the pregenome and postgenome-wide association studies era: a bibliometric analysis and network visualization. | Zakaria WNA et al. | β | 2023 | β |
| Genetic and epigenetic control of the plant metabolome. | Hayashi K et al. | β | 2023 | β |
| Genetic architecture of non-syndromic skeletal class III malocclusion. | Zhou X et al. | β | 2023 | β |
| Genetics and Epigenetics: Implications for the Life Course of Gestational Diabetes. | Lowe WL | β | 2023 | β |
| Genome-wide identification and expression analysis of the JMJ-C gene family in melon (Cucumis melo L.) reveals their potential role in fruit development. | Jin W et al. | β | 2023 | β |
| Genome-Wide Identification of Histone Deacetylases and Their Roles Related with Light Response in Tartary Buckwheat (<i>Fagopyrum tataricum</i>). | Yan H et al. | β | 2023 | β |
| H3.3 contributes to chromatin accessibility and transcription factor binding at promoter-proximal regulatory elements in embryonic stem cells. | Tafessu A et al. | β | 2023 | β |
| H3 histone methylation landscape in male urogenital cancers: from molecular mechanisms to epigenetic biomarkers and therapeutic targets. | Burlibasa L et al. | β | 2023 | β |
| Haploinsufficiency of NFKBIA reshapes the epigenome antipodal to the IDH mutation and imparts disease fate in diffuse gliomas. | Bredel M et al. | β | 2023 | β |
| Haplotype mapping of H3K27me3-associated chromatin interactions defines topological regulation of gene silencing in rice. | Ouyang W et al. | β | 2023 | β |
| Heterochromatin definition and function. | Bell O et al. | β | 2023 | β |
| Histone 4 lysine 5/12 acetylation enables developmental plasticity of Pristionchus mouth form. | Werner MS et al. | β | 2023 | β |
| Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin. | Liu N et al. | β | 2023 | β |
| Histone H3 lysine 27 trimethylation suppresses jasmonate biosynthesis and signaling to affect male fertility under high temperature in cotton. | Li Y et al. | β | 2023 | β |
| Histone Modification of Colorectal Cancer by Natural Products. | Geng Z et al. | β | 2023 | β |
| Host gene and its guest: short story about relation of long-noncoding <i>MIR31HG</i> transcript and microRNA <i>miR-31</i>. | Kolenda T et al. | β | 2023 | β |
| Human Adenovirus Gene Expression and Replication Is Regulated through Dynamic Changes in Nucleoprotein Structure throughout Infection. | Jennings MR et al. | β | 2023 | β |
| Hypermethylation of the serotonin transporter gene and paternal parenting styles in untreated anorexia nervosa patients: A pilot study. | He Q et al. | β | 2023 | β |
| Hypoxia and renal fibrosis. | Naas S et al. | β | 2023 | β |
| <i>Arabidopsis thaliana</i>: a powerful model organism to explore histone modifications and their upstream regulations. | Yu Y et al. | β | 2023 | β |
| Imaging-Based In Situ Analysis of 5-Methylcytosine at Low Repetitive Single Gene Loci with Transcription-Activator-Like Effector Probes. | Jung A et al. | β | 2023 | β |
| Immune-epigenetic crosstalk in haematological malignancies. | Wong H et al. | β | 2023 | β |
| Impact of Germline Depletion of Bonus on Chromatin State in <i>Drosophila</i> Ovaries. | Godneeva B et al. | β | 2023 | β |
| Impaired ATF3 signaling involves SNAP25 in SOD1 mutant ALS patients. | Yazar V et al. | β | 2023 | β |
| Impaired RNA Binding Does Not Prevent Histone Modification Changes in a FUS ALS/FTD Yeast Model. | Bennett SA et al. | β | 2023 | β |
| Inflammation, stress and depression: An exploration of ketamine's therapeutic profile. | Johnston JN et al. | β | 2023 | β |
| Insight into the Potential Mechanisms of Endocrine Disruption by Dietary Phytoestrogens in the Context of the Etiopathogenesis of Endometriosis. | Szukiewicz D | β | 2023 | β |
| Integrated analysis of ATAC-seq and RNA-seq reveals the transcriptional regulation network in SLE. | Wu J et al. | β | 2023 | β |
| Interaction between N<sup>6</sup>-methyladenosine modification and the tumor microenvironment in colorectal cancer. | Yao J et al. | β | 2023 | β |
| Interplay between m<sup>6</sup> A epitranscriptome and epigenome in cancer: current knowledge and therapeutic perspectives. | Bove G et al. | β | 2023 | β |
| Interplay between PML NBs and HIRA for H3.3 dynamics following type I interferon stimulus. | Kleijwegt C et al. | β | 2023 | β |
| Interpreting non-coding disease-associated human variants using single-cell epigenomics. | Gaulton KJ et al. | β | 2023 | β |
| Intrinsic Effects of Exposome in Atopic Dermatitis: Genomics, Epigenomics and Regulatory Layers. | Grafanaki K et al. | β | 2023 | β |
| Involvement of the H3.3 Histone Variant in the Epigenetic Regulation of Gene Expression in the Nervous System, in Both Physiological and Pathological Conditions. | Di Liegro CM et al. | β | 2023 | β |
| Iron Oxide Nanoparticles with and without Cobalt Functionalization Provoke Changes in the Transcription Profile via Epigenetic Modulation of Enhancer Activity. | Gamberoni F et al. | β | 2023 | β |
| KDM6A/B Demethylases in Gut Homeostasis. | Soshnikova N | β | 2023 | β |
| KDM6A Loss Triggers an Epigenetic Switch That Disrupts Urothelial Differentiation and Drives Cell Proliferation in Bladder Cancer. | Qiu H et al. | β | 2023 | β |
| Linking Histone Methylation States and <i>hsp</i> Transcriptional Regulation in Thermo-Tolerant and Thermo-Susceptible <i>A. mellifera</i> L. Subspecies in Response to Heat Stress. | Alattal YZ et al. | β | 2023 | β |
| Loss of Histone Methyltransferase KMT2D Attenuates Angiogenesis in the Ischemic Heart by Inhibiting the Transcriptional Activation of VEGF-A. | Meng XM et al. | β | 2023 | β |
| L-type calcium channels and neuropsychiatric diseases: Insights into genetic risk variant-associated genomic regulation and impact on brain development. | Baker MR et al. | β | 2023 | β |
| Manifold epigenetics: A conceptual model that guides engineering strategies to improve whole-body regenerative health. | Ung CY et al. | β | 2023 | β |
| Mass-Cytometry-Based Quantification of Global Histone Post-Translational Modifications at Single-Cell Resolution Across Peripheral Immune Cells in IBD. | Bai L et al. | β | 2023 | β |
| Mechanisms of epigenetic regulation of transcription by lncRNAs in plants. | Tremblay BJM et al. | β | 2023 | β |
| Mechanistic aspects of reversible methylation modifications of arginine and lysine of nuclear histones and their roles in human colon cancer. | Roy A et al. | β | 2023 | β |
| Metformin-mediated epigenetic modifications in diabetes and associated conditions: Biological and clinical relevance. | Giordo R et al. | β | 2023 | β |
| Methylation haplotypes of the insulin gene promoter in children and adolescents with type 1 diabetes: Can a dimensionality reduction approach predict the disease? | Kotanidou EP et al. | β | 2023 | β |
| Methylome and proteome integration in human skeletal muscle uncover group and individual responses to high-intensity interval training. | Jacques M et al. | β | 2023 | β |
| Methylomics and cancer: the current state of methylation profiling and marker development for clinical care. | Liu C et al. | β | 2023 | β |
| METTL3 Mediates Epithelial-Mesenchymal Transition by Modulating FOXO1 mRNA N<sup>6</sup> -Methyladenosine-Dependent YTHDF2 Binding: A Novel Mechanism of Radiation-Induced Lung Injury. | Feng Y et al. | β | 2023 | β |
| METTL3 promotes pancreatic cancer proliferation and stemness by increasing stability of ID2 mRNA in a m6A-dependent manner. | Chen J et al. | β | 2023 | β |
| Modulating epigenetic modifications for cancer therapy (Review). | Castro-MuΓ±oz LJ et al. | β | 2023 | β |
| More than bad luck: Cancer and aging are linked to replication-driven changes to the epigenome. | Minteer CJ et al. | β | 2023 | β |
| Multiplexed, single-molecule, epigenetic analysis of plasma-isolated nucleosomes for cancer diagnostics. | Fedyuk V et al. | β | 2023 | β |
| Navigating bottlenecks and trade-offs in genomic data analysis. | Berger B et al. | β | 2023 | β |
| NLRP3: a new therapeutic target in alcoholic liver disease. | Brahadeeswaran S et al. | β | 2023 | β |
| Novel Auger-Electron-Emitting <sup>191</sup>Pt-Labeled Pyrrole-Imidazole Polyamide Targeting MYCN Increases Cytotoxicity and Cytosolic dsDNA Granules in MYCN-Amplified Neuroblastoma. | Obata H et al. | β | 2023 | β |
| Nuclear Phosphoinositides as Key Determinants of Nuclear Functions. | Vidalle MC et al. | β | 2023 | β |
| Old and newly synthesized histones are asymmetrically distributed in Drosophila intestinal stem cell divisions. | Zion EH et al. | β | 2023 | β |
| Old school, new rules: floral meristem development revealed by 3D gene expression atlases and high-resolution transcription factor-chromatin dynamics. | Pelayo MA et al. | β | 2023 | β |
| On the accuracy of the epigenetic copy machine: comprehensive specificity analysis of the DNMT1 DNA methyltransferase. | Adam S et al. | β | 2023 | β |
| On the road to resilience: Epigenetic effects of meditation. | Verdone L et al. | β | 2023 | β |
| Pan-cancer landscape of epigenetic factor expression predicts tumor outcome. | Cheng MW et al. | β | 2023 | β |
| peaksat: an R package for ChIP-seq peak saturation analysis. | Boyd JR et al. | β | 2023 | β |
| Phenotypic plasticity in the monoclonal marbled crayfish is associated with very low genetic diversity but pronounced epigenetic diversity. | Vogt G | β | 2023 | β |
| Post-transcriptional control of antifungal resistance in human fungal pathogens. | Sharma C et al. | β | 2023 | β |
| PRC2-independent actions of H3.3K27M in embryonic stem cell differentiation. | Cohen LRZ et al. | β | 2023 | β |
| PROTACS: A technology with a gold rush-like atmosphere. | Wang YW et al. | β | 2023 | β |
| Proteomics-based trapping with single or multiple inactive mutants reproducibly profiles histone deacetylase 1 substrates. | Herath KE et al. | β | 2023 | β |
| Protocol of the Double-Click Seq Method to Evaluate the Deposition Bias of Chromatin Proteins. | van der Wouden PE et al. | β | 2023 | β |
| Psychogenetic, genetic and epigenetic mechanisms in Candida auris: Role in drug resistance. | Rabaan AA et al. | β | 2023 | β |
| Rare diseases of epigenetic origin: Challenges and opportunities. | Fu MP et al. | β | 2023 | β |
| Recapitulation of patient-specific 3D chromatin conformation using machine learning. | Xu D et al. | β | 2023 | β |
| Refined read-out: The hUHRF1 Tandem-Tudor domain prefers binding to histone H3 tails containing K4me1 in the context of H3K9me2/3. | Choudalakis M et al. | β | 2023 | β |
| Regulatory Mechanisms and Reversal of CD8<sup>+</sup>T Cell Exhaustion: A Literature Review. | Zhu W et al. | β | 2023 | β |
| Reprogramming of the Genome-Wide DNA Methylation Landscape in Three-Dimensional Cancer Cell Cultures. | Heredia-Mendez AJ et al. | β | 2023 | β |
| Reversible switching and stability of the epigenetic memory system in bacteria. | Graf D et al. | β | 2023 | β |
| scm<sup>6</sup>A-seq reveals single-cell landscapes of the dynamic m<sup>6</sup>A during oocyte maturation and early embryonic development. | Yao H et al. | β | 2023 | β |
| Sepsis-associated acute kidney injury: consensus report of the 28th Acute Disease Quality Initiative workgroup. | Zarbock A et al. | β | 2023 | β |
| Sequential Ubiquitination and Phosphorylation Epigenetics Reshaping by MG132-Loaded Fe-MOF Disarms Treatment Resistance to Repulse Metastatic Colorectal Cancer. | Bu Z et al. | β | 2023 | β |
| Sex-specific epigenetic programming in renal fibrosis and inflammation. | Kumar P et al. | β | 2023 | β |
| Structure-Activity Relationships in Nucleic-Acid-Templated Vectors Based on Peptidic Dynamic Covalent Polymers. | Su DD et al. | β | 2023 | β |
| Studying histone inheritance in different systems using imaging-based methods and perspectives. | Zion E et al. | β | 2023 | β |
| Substance use disorders: a comprehensive update of classification, epidemiology, neurobiology, clinical aspects, treatment and prevention. | Volkow ND et al. | β | 2023 | β |
| Symmetric inheritance of parental histones governs epigenome maintenance and embryonic stem cell identity. | Wenger A et al. | β | 2023 | β |
| Systems genetics approaches for understanding complex traits with relevance for human disease. | Allayee H et al. | β | 2023 | β |
| Targeting Epigenetic Mechanisms: A Boon for Cancer Immunotherapy. | Parab A et al. | β | 2023 | β |
| The ancestral chromatin landscape of land plants. | Hisanaga T et al. | β | 2023 | β |
| The application of PROTAC in HDAC. | Chen S et al. | β | 2023 | β |
| The catalytic domains of all human KDM5 JmjC demethylases catalyse N-methyl arginine demethylation. | Bonnici J et al. | β | 2023 | β |
| The effects of RNA.DNA-DNA triple helices on nucleosome structures and dynamics. | Kohestani H et al. | β | 2023 | β |
| The epigenetic regulator BRD4 is required for myofibroblast differentiation of knee fibroblasts. | Dudakovic A et al. | β | 2023 | β |
| The epigenome and the many facets of cancer drug tolerance. | Moore PC et al. | β | 2023 | β |
| The Growth and Conidiation of <i>Purpureocillium lavendulum</i> Are Co-Regulated by Nitrogen Sources and Histone H3K14 Acetylation. | Tang P et al. | β | 2023 | β |
| The impact of epigenetic mechanisms in migraine: Current knowledge and future directions. | Gallardo VJ et al. | β | 2023 | β |
| The impact of epigenetic modifications on allogeneic hematopoietic stem cell transplantation. | Ktena YP et al. | β | 2023 | β |
| The Importance of the "Time Factor" for the Evaluation of Inhibition Mechanisms: The Case of Selected HDAC6 Inhibitors. | Cellupica E et al. | β | 2023 | β |
| The interplay between DNA methylation and cardiac autonomic system functioning: a systematic review. | Dos Santos Oliveira NC et al. | β | 2023 | β |
| The MMP-2 histone H3 N-terminal tail protease is selectively targeted to the transcription start sites of active genes. | Weekley BH et al. | β | 2023 | β |
| The potential role of RNA modification in skin diseases, as well as the recent advances in its detection methods and therapeutic agents. | Yu Y et al. | β | 2023 | β |
| The T1150A cancer mutant of the protein lysine dimethyltransferase NSD2 can introduce H3K36 trimethylation. | Khella MS et al. | β | 2023 | β |
| To target or not to target? The role of DNA and histone methylation in bacterial infections. | Barbachowska M et al. | β | 2023 | β |
| Toward the Development of Epigenome Editing-Based Therapeutics: Potentials and Challenges. | Ueda J et al. | β | 2023 | β |
| Transcriptional and epigenetic regulation of microglia in substance use disorders. | Vilca SJ et al. | β | 2023 | β |
| Tumor cell plasticity in targeted therapy-induced resistance: mechanisms and new strategies. | Shi ZD et al. | β | 2023 | β |
| Two target gene activation pathways for orphan ERR nuclear receptors. | Nakadai T et al. | β | 2023 | β |
| Unraveling the Genetic Basis of Feed Efficiency in Cattle through Integrated DNA Methylation and CattleGTEx Analysis. | Hu Z et al. | β | 2023 | β |
| Unveiling the role of GAS41 in cancer progression. | Ji K et al. | β | 2023 | β |
| UV-DDB as a General Sensor of DNA Damage in Chromatin: Multifaceted Approaches to Assess Its Direct Role in Base Excision Repair. | Raja SJ et al. | β | 2023 | β |
| Vitamin C: From nutrition to oxygen sensing and epigenetics. | Kietzmann T | β | 2023 | β |
| Vitamin D Metabolism Genes Are Differentially Methylated in Individuals with Chronic Knee Pain. | Strath LJ et al. | β | 2023 | β |
| Working a second job: Cell adhesion proteins that moonlight in the nucleus. | Haage A et al. | β | 2023 | β |
| 2-Hydroxyglutarate destabilizes chromatin regulatory landscape and lineage fidelity to promote cellular heterogeneity. | Kusi M et al. | β | 2022 | β |
| A Comprehensive Review of BET Protein Biochemistry, Physiology, and Pathological Roles. | Ali HA et al. | β | 2022 | β |
| Advances and perspectives of proteolysis targeting chimeras (PROTACs) in drug discovery. | Xi JY et al. | β | 2022 | β |
| AIRE in context: Leveraging chromatin plasticity to trigger ectopic gene expression. | Kaiser C et al. | β | 2022 | β |
| Alternative Mechanisms for DNA Engagement by BET Bromodomain-Containing Proteins. | Kalra P et al. | β | 2022 | β |
| An EHMT2/NFYA-ALDH2 signaling axis modulates the RAF pathway to regulate paclitaxel resistance in lung cancer. | Wang W et al. | β | 2022 | β |
| An epigenetically inherited UV hyper-resistance phenotype in Saccharomyces cerevisiae. | Reardon RM et al. | β | 2022 | β |
| A novel dual epigenetic approach targeting BET proteins and HDACs in Group 3 (MYC-driven) Medulloblastoma. | Kling MJ et al. | β | 2022 | β |
| A novel histone deacetylase inhibitor-based approach to eliminate microglia and retain astrocyte properties in glial cell culture. | He XB et al. | β | 2022 | β |
| A phylogenetic and proteomic reconstruction of eukaryotic chromatin evolution. | Grau-BovΓ© X et al. | β | 2022 | β |
| ARID1A loss induces polymorphonuclear myeloid-derived suppressor cell chemotaxis and promotes prostate cancer progression. | Li N et al. | β | 2022 | β |
| Ash2l, an obligatory component of H3K4 methylation complexes, regulates neural crest development. | Mohammadparast S et al. | β | 2022 | β |
| Association between DNA methylation variability and self-reported exposure to heavy metals. | Freydenzon A et al. | β | 2022 | β |
| Bacterial N4-methylcytosine as an epigenetic mark in eukaryotic DNA. | Rodriguez F et al. | β | 2022 | β |
| Beyond sequencing: machine learning algorithms extract biology hidden in Nanopore signal data. | Wan YK et al. | β | 2022 | β |
| Biological ageing with HIV infection: evaluating the geroscience hypothesis. | Montano M et al. | β | 2022 | β |
| Black Tea Reduces Diet-Induced Obesity in Mice via Modulation of Gut Microbiota and Gene Expression in Host Tissues. | Liu X et al. | β | 2022 | β |
| BRD4-directed super-enhancer organization of transcription repression programs links to chemotherapeutic efficacy in breast cancer. | Liu B et al. | β | 2022 | β |
| Brd4 is required for chondrocyte differentiation and endochondral ossification. | Paradise CR et al. | β | 2022 | β |
| Bringing precision oncology to cellular resolution with single-cell genomics. | Xia Y et al. | β | 2022 | β |
| Bromodomain and Extra-Terminal Protein Inhibitors: Biologic Insights and Therapeutic Potential in Pediatric Brain Tumors. | Groves A et al. | β | 2022 | β |
| Bromodomains regulate dynamic targeting of the PBAF chromatin-remodeling complex to chromatin hubs. | Kenworthy CA et al. | β | 2022 | β |
| Cancer Epigenetics: An Overview. | Recillas-Targa F | β | 2022 | β |
| Cancer metabolism and tumor microenvironment: fostering each other? | Yuan Y et al. | β | 2022 | β |
| Cell-type-specific DNA methylation analysis of the frontal cortices of mutant Polg1 transgenic mice with neuronal accumulation of deleted mitochondrial DNA. | Sugawara H et al. | β | 2022 | β |
| Challenges in elucidating bacteria-host epigenetic dynamics. | Nagaraja V et al. | β | 2022 | β |
| Characterization of a KDM5 small molecule inhibitor with antiviral activity against hepatitis B virus. | Gilmore SA et al. | β | 2022 | β |
| Characterization of body composition and liver epigenetic markers during periods of negative energy balance and subsequent compensatory growth in postpubertal beef bulls. | Moura FH et al. | β | 2022 | β |
| Chemical biology and pharmacology of histone lysine methylation inhibitors. | Barghout SH et al. | β | 2022 | β |
| Chromatin Accessibility Analysis from Fresh and Cryopreserved Human Ovarian Follicles. | Shannon J et al. | β | 2022 | β |
| Chromatin Structure and Dynamics: Focus on Neuronal Differentiation and Pathological Implication. | Nothof SA et al. | β | 2022 | β |
| Ciliate research: From myth to trendsetting science. | Plattner H | β | 2022 | β |
| Circulating cell free DNA and citrullinated histone H3 as useful biomarkers of NETosis in endometrial cancer. | Ronchetti L et al. | β | 2022 | β |
| Classification of early age facial growth pattern and identification of the genetic basis in two Korean populations. | Cha MY et al. | β | 2022 | β |
| Clonal Selection and Evolution of HTLV-1-Infected Cells Driven by Genetic and Epigenetic Alteration. | Yamagishi M et al. | β | 2022 | β |
| Collateral Damage Occurs When Using Photosensitizer Probes to Detect or Modulate Nucleic Acid Modifications. | Fleming AM et al. | β | 2022 | β |
| Complex Elucidation of Cells-of-Origin in Pediatric Soft Tissue Sarcoma: From Concepts to Real Life, Hide-and-Seek through Epigenetic and Transcriptional Reprogramming. | Savary C et al. | β | 2022 | β |
| Comprehensive analyses reveal the role of histone deacetylase genes in prognosis and immune response in low-grade glioma. | Shen L et al. | β | 2022 | β |
| Computational modeling of chromatin accessibility identified important epigenomic regulators. | Zhao Y et al. | β | 2022 | β |
| Covalent Modification of Bromodomain Proteins by Peptides Containing a DNA Damage-Induced, Histone Post-Translational Modification. | Jacinto MP et al. | β | 2022 | β |
| Curcumin: An epigenetic regulator and its application in cancer. | Ming T et al. | β | 2022 | β |
| Decoding the dynamic H3K9cr landscapes during neural commitment of P19 embryonal carcinoma cells. | Dai SK et al. | β | 2022 | β |
| Defining Proximity Proteome of Histone Modifications by Antibody-mediated Protein A-APEX2 Labeling. | Li X et al. | β | 2022 | β |
| Degradation of NSD3: What to Myc of it all? | Green AI et al. | β | 2022 | β |
| De novo DNA methylation induced by circulating extracellular vesicles from acute coronary syndrome patients. | Schiano C et al. | β | 2022 | β |
| Differential condensation of sister chromatids acts with Cdc6 to ensure asynchronous S-phase entry in Drosophila male germline stem cell lineage. | Ranjan R et al. | β | 2022 | β |
| Dissecting Plant Gene Functions Using CRISPR Toolsets for Crop Improvement. | Zhang RX et al. | β | 2022 | β |
| Dissecting the Kinetic Mechanism of Human Lysine Methyltransferase 2D and Its Interactions with the WRAD2 Complex. | Edwardes LV et al. | β | 2022 | β |
| Distribution Pattern of N6-Methyladenine DNA Modification in the Seashore Paspalum (<i>Paspalum vaginatum</i>) Genome. | Hao JS et al. | β | 2022 | β |
| DNA methylation-based diagnostic, prognostic, and predictive biomarkers in colorectal cancer. | MΓΌller D et al. | β | 2022 | β |
| Down-syndrome-induced senescence disrupts the nuclear architecture of neural progenitors. | Meharena HS et al. | β | 2022 | β |
| Emerging Role of Epigenetic Alterations as Biomarkers and Novel Targets for Treatments in Pancreatic Ductal Adenocarcinoma. | RoalsΓΈ MTT et al. | β | 2022 | β |
| Endogenous Retroviral Sequences Behave as Putative Enhancers Controlling Gene Expression through HP1-Regulated Long-Range Chromatin Interactions. | Calvet S et al. | β | 2022 | β |
| Environmental Adaptation of Genetically Uniform Organisms with the Help of Epigenetic Mechanisms-An Insightful Perspective on Ecoepigenetics. | Vogt G | β | 2022 | β |
| Enzymology of Mammalian DNA Methyltransferases. | Jurkowska RZ et al. | β | 2022 | β |
| Epigenetic and Transcriptional Signaling in Ewing Sarcoma-Disease Etiology and Therapeutic Opportunities. | Li M et al. | β | 2022 | β |
| Epigenetic Aspects and Prospects in Autoimmune Hepatitis. | Czaja AJ | β | 2022 | β |
| Epigenetic cell memory: The gene's inner chromatin modification circuit. | Bruno S et al. | β | 2022 | β |
| Epigenetic Changes and Chromatin Reorganization in Brain Function: Lessons from Fear Memory Ensemble and Alzheimer's Disease. | van Zundert B et al. | β | 2022 | β |
| Epigenetic drug ameliorated type 1 diabetes via decreased generation of Th1 and Th17 subsets and restoration of self-tolerance in CD4<sup>+</sup> T cells. | Patel V et al. | β | 2022 | β |
| Epigenetic Effects of Addictive Drugs in the Nucleus Accumbens. | Anderson EM et al. | β | 2022 | β |
| Epigenetic Effects of Healthy Foods and Lifestyle Habits from the Southern European Atlantic Diet Pattern: A Narrative Review. | Lorenzo PM et al. | β | 2022 | β |
| Epigenetic geneΒ alterations in metastatic solid tumours: results from the prospective precision medicine MOSCATO and MATCH-R trials. | Martin-Romano P et al. | β | 2022 | β |
| Epigenetic machinery is functionally conserved in cephalopods. | Macchi F et al. | β | 2022 | β |
| Epigenetic mechanisms affect the curled leaf phenotype in the hypomethylated ddc mutant of Arabidopsis thaliana. | Forgione I et al. | β | 2022 | β |
| Epigenetic modifications in metabolic memory: What are the memories, and can we erase them? | Chen Z et al. | β | 2022 | β |
| Epigenetic Modifiers Alter Host Cell Transcription to Promote Toxoplasma Infection. | Rosenberg A et al. | β | 2022 | β |
| Epigenetic regulation by gut microbiota. | Woo V et al. | β | 2022 | β |
| Epigenetic regulation by long noncoding RNAs in osteo-/adipogenic differentiation of mesenchymal stromal cells and degenerative bone diseases. | Xia K et al. | β | 2022 | β |
| Epigenetic Regulation in Chromium-, Nickel- and Cadmium-Induced Carcinogenesis. | Zhao L et al. | β | 2022 | β |
| Epigenetic Regulation of Antifungal Drug Resistance. | Patra S et al. | β | 2022 | β |
| Epigenetic regulation of human non-coding RNA gene transcription. | Morselli M et al. | β | 2022 | β |
| Epigenetic regulation of natural killer cell memory. | Lau CM et al. | β | 2022 | β |
| Epigenetic regulation of nervous system development and function. | MacDonald JL et al. | β | 2022 | β |
| Epigenetic Regulation of Optic Nerve Development, Protection, and Repair. | Ashok A et al. | β | 2022 | β |
| Epigenetic regulation of salinity stress responses in cereals. | Rashid MM et al. | β | 2022 | β |
| Epigenetic regulation of T cell exhaustion. | Belk JA et al. | β | 2022 | β |
| Epigenetic regulation of thermomorphogenesis in <i>Arabidopsis thaliana</i>. | Hou Y et al. | β | 2022 | β |
| Epigenetics and CD8<sup>+</sup> T cell memory. | Montacchiesi G et al. | β | 2022 | β |
| Epigenetics and its role in effecting agronomical traits. | Gupta C et al. | β | 2022 | β |
| Epigenetics in susceptibility, progression, and diagnosis of periodontitis. | Suzuki S et al. | β | 2022 | β |
| Epigenetics of alcohol-related liver diseases. | Habash NW et al. | β | 2022 | β |
| EPIKOL, a chromatin-focused CRISPR/Cas9-based screening platform, to identify cancer-specific epigenetic vulnerabilities. | Yedier-Bayram O et al. | β | 2022 | β |
| Evolutionary History and Functional Diversification of the <i>JmjC</i> Domain-Containing Histone Demethylase Gene Family in Plants. | Ma S et al. | β | 2022 | β |
| Evolved DNA Duplex Readers for Strand-Asymmetrically Modified 5-Hydroxymethylcytosine/5-Methylcytosine CpG Dyads. | Buchmuller BC et al. | β | 2022 | β |
| Exploring Epigenomic Datasets by ChIPseeker. | Wang Q et al. | β | 2022 | β |
| EZH2 restricts <i>Tcf7</i> DNA methylation and promotes T<sub>FH</sub> differentiation during acute viral infection. | Luo Y et al. | β | 2022 | β |
| FOXK2 transcription factor and its roles in tumorigenesis (Review). | Wang Z et al. | β | 2022 | β |
| Functional Hallmarks of Healthy Macrophage Responses: Their Regulatory Basis and Disease Relevance. | Sheu KM et al. | β | 2022 | β |
| Gamma-glutamyltransferase of Helicobacter pylori alters the proliferation, migration, and pluripotency of mesenchymal stem cells by affecting metabolism and methylation status. | Wang Z et al. | β | 2022 | β |
| Generation of DNA Methylation Signatures and Classification of Variants in Rare Neurodevelopmental Disorders Using EpigenCentral. | Awamleh Z et al. | β | 2022 | β |
| Genetic and epigenetic interplay allows rapid transgenerational adaptation to metal pollution in zebrafish. | Pierron F et al. | β | 2022 | β |
| Genetic and Physiological Responses to Heat Stress in <i>Brassica napus</i>. | Kourani M et al. | β | 2022 | β |
| Genetics in Behcet's Disease: An Update Review. | Gao Y et al. | β | 2022 | β |
| Genome-wide identification and expression analysis of JmjC domain-containing genes in grape under MTA treatment. | Cheng YZ et al. | β | 2022 | β |
| Genome-wide localization of histone variants in Toxoplasma gondii implicates variant exchange in stage-specific gene expression. | Nardelli SC et al. | β | 2022 | β |
| Genomic Medicine in Periodontal Disease: Old Issue, New Insights. | GonΓ§alves-Anjo N et al. | β | 2022 | β |
| Germline Abnormalities in DNA Methylation and Histone Modification and Associated Cancer Risk. | Fernandez JA et al. | β | 2022 | β |
| Global 5mC and 5hmC DNA Levels in Human Sperm Subpopulations with Differentially Protaminated Chromatin in Normo- and Oligoasthenozoospermic Males. | Olszewska M et al. | β | 2022 | β |
| H3K9 methylation drives resistance to androgen receptor-antagonist therapy in prostate cancer. | Baratchian M et al. | β | 2022 | β |
| H3K9 trimethylation in active chromatin restricts the usage of functional CTCF sites in SINE B2 repeats. | Gualdrini F et al. | β | 2022 | β |
| HDAC2 Is Involved in the Regulation of BRN3A in Melanocytes and Melanoma. | Heppt MV et al. | β | 2022 | β |
| Hepatitis B virus X protein mediated epigenetic alterations in the pathogenesis of hepatocellular carcinoma. | Yang L et al. | β | 2022 | β |
| High-affinity chromodomains engineered for improved detection of histone methylation and enhanced CRISPR-based gene repression. | Veggiani G et al. | β | 2022 | β |
| High-dimension to high-dimension screening for detecting genome-wide epigenetic and noncoding RNA regulators of gene expression. | Ke H et al. | β | 2022 | β |
| High fidelity epigenetic inheritance: Information theoretic model predicts threshold filling of histone modifications post replication. | Ramakrishnan N et al. | β | 2022 | β |
| High Risk-Human Papillomavirus in HNSCC: Present and Future Challenges for Epigenetic Therapies. | Ghiani L et al. | β | 2022 | β |
| Histone Demethylase AMX-1 Regulates Fertility in a p53/CEP-1 Dependent Manner. | Ren X et al. | β | 2022 | β |
| Histone demethylase JMJD3 downregulation protects against aberrant force-induced osteoarthritis through epigenetic control of NR4A1. | Jin Y et al. | β | 2022 | β |
| Histone editing elucidates the functional roles of H3K27 methylation and acetylation in mammals. | Sankar A et al. | β | 2022 | β |
| Histone H4K20 Trimethylation Is Decreased in Murine Models of Heart Disease. | Hickenlooper SM et al. | β | 2022 | β |
| Histone-lysine N-methyltransferase 2 (KMT2) complexes - a new perspective. | Poreba E et al. | β | 2022 | β |
| Histone Methyltransferase DOT1L as a Promising Epigenetic Target for Treatment of Solid Tumors. | Alexandrova E et al. | β | 2022 | β |
| Histone Variant macroH2A1.1 Enhances Nonhomologous End Joining-dependent DNA Double-strand-break Repair and Reprogramming Efficiency of Human iPSCs. | Giallongo S et al. | β | 2022 | β |
| Histone variants and modifications during abiotic stress response. | Nunez-Vazquez R et al. | β | 2022 | β |
| HIV-1 Preintegration Complex Preferentially Integrates the Viral DNA into Nucleosomes Containing Trimethylated Histone 3-Lysine 36 Modification and Flanking Linker DNA. | Sapp N et al. | β | 2022 | β |
| How to train your cell - Towards controlling phenotypes by harnessing the epigenome of Chinese hamster ovary production cell lines. | Marx N et al. | β | 2022 | β |
| HP1 oligomerization compensates for low-affinity H3K9me recognition and provides a tunable mechanism for heterochromatin-specific localization. | Biswas S et al. | β | 2022 | β |
| Human testis-specific Y-encoded protein-like protein 5 is a histone H3/H4-specific chaperone that facilitates histone deposition inΒ vitro. | Dalui S et al. | β | 2022 | β |
| Hydrophobic cavity-directed azide-acetyllysine photochemistry for profiling non-histone interacting partners of bromodomain protein 1. | Kuwik J et al. | β | 2022 | β |
| <i>Botrytis cinerea</i> Loss and Restoration of Virulence during In Vitro Culture Follows Flux in Global DNA Methylation. | Breen J et al. | β | 2022 | β |
| Identification and analysis of proline-rich proteins and hybrid proline-rich proteins super family genes from <i>Sorghum bicolor</i> and their expression patterns to abiotic stress and zinc stimuli. | Rajasheker G et al. | β | 2022 | β |
| Identification of Lsd1-interacting non-coding RNAs as regulators of fly oogenesis. | Shao TL et al. | β | 2022 | β |
| Impact of histone modifier-induced protection against autoimmune encephalomyelitis on multiple sclerosis treatment. | Jayaraman S et al. | β | 2022 | β |
| Improving Infinium MethylationEPIC data processing: re-annotation of enhancers and long noncoding RNA genes and benchmarking of normalization methods. | Bizet M et al. | β | 2022 | β |
| Inhibition of Histone H3 Lysine-27 Demethylase Activity Relieves Rheumatoid Arthritis Symptoms <i>via</i> Repression of IL6 Transcription in Macrophages. | Zhao Z et al. | β | 2022 | β |
| Integrating extrusion complex-associated pattern to predict cell type-specific long-range chromatin loops. | Deng Y et al. | β | 2022 | β |
| Involvement of histone deacetylase CsHDA2 in regulating (<i>E</i>)-nerolidol formation in tea (<i>Camellia sinensis</i>) exposed to tea green leafhopper infestation. | Gu D et al. | β | 2022 | β |
| JmjC Family of Histone Demethylases Form Nuclear Condensates. | Vicioso-Mantis M et al. | β | 2022 | β |
| Large-Scale Chromatin Rearrangements in Cancer. | Yamaguchi K et al. | β | 2022 | β |
| Lipid Metabolism and Epigenetics Crosstalk in Prostate Cancer. | Pardo JC et al. | β | 2022 | β |
| Lipid Metabolism Heterogeneity and Crosstalk with Mitochondria Functions Drive Breast Cancer Progression and Drug Resistance. | Azam A et al. | β | 2022 | β |
| Loss of TET reprograms Wnt signaling through impaired demethylation to promote lung cancer development. | Xu Q et al. | β | 2022 | β |
| LSD1 for the Targeted Regulation of Adipose Tissue. | Chen L et al. | β | 2022 | β |
| Lysine-Specific Demethylase 1 (LSD1) epigenetically controls osteoblast differentiation. | Rummukainen P et al. | β | 2022 | β |
| Mechanisms of chromatin-based epigenetic inheritance. | Du W et al. | β | 2022 | β |
| Mechanisms of gene regulation by histone degradation in adaptation of yeast: an overview of recent advances. | Khan SU et al. | β | 2022 | β |
| Mechanistic basis of the increased methylation activity of the SETD2 protein lysine methyltransferase towards a designed super-substrate peptide. | Schnee P et al. | β | 2022 | β |
| Mechanistic insights into glucose induced vascular epigenetic reprogramming in type 2 diabetes. | Dhawan P et al. | β | 2022 | β |
| Merkel cell polyomavirus and associated Merkel cell carcinoma. | Yang JF et al. | β | 2022 | β |
| Methyltransferase-like 14 suppresses growth and metastasis of renal cell carcinoma by decreasing long noncoding RNA NEAT1. | Liu T et al. | β | 2022 | β |
| Methyltransferase like 3-mediated N6-methylatidin methylation inhibits vascular smooth muscle cells phenotype switching <i>via</i> promoting phosphatidylinositol 3-kinase mRNA decay. | Zhao Y et al. | β | 2022 | β |
| Microbiome as an immune regulator in health, disease, and therapeutics. | Juarez VM et al. | β | 2022 | β |
| Mitochondrial superoxide targets energy metabolism to modulate epigenetic regulation of NRF2-mediated transcription. | Dhar SK et al. | β | 2022 | β |
| Modeling Susceptibility to Cardiotoxicity in Cancer Therapy Using Human iPSC-Derived Cardiac Cells and Systems Biology. | Mullen M et al. | β | 2022 | β |
| Modulation of the Response to <i>Mycobacterium leprae</i> and Pathogenesis of Leprosy. | Cabral N et al. | β | 2022 | β |
| Molecular mechanisms of transgenerational epigenetic inheritance. | Fitz-James MH et al. | β | 2022 | β |
| Msl3 promotes germline stem cell differentiation in female Drosophila. | McCarthy A et al. | β | 2022 | β |
| Multi-omic profiling of histone variant H3.3 lysine 27 methylation reveals a distinct role from canonical H3 in stem cell differentiation. | Kori Y et al. | β | 2022 | β |
| Multi-omics analysis of naΓ―ve B cells of patients harboring the C104R mutation in TACI. | Ramirez N et al. | β | 2022 | β |
| Multiscale modelling of chromatin organisation: Resolving nucleosomes at near-atomistic resolution inside genes. | Huertas J et al. | β | 2022 | β |
| Mutational Alterations of DNA Methylation-related Genes CTCF, ZFP57, and ATF7IP Genes in Colon Cancers. | Moon SW et al. | β | 2022 | β |
| Neurobiological Highlights of Cognitive Impairment in Psychiatric Disorders. | Morozova A et al. | β | 2022 | β |
| Newly Identified Deficiencies in the Multiple Sclerosis Central Nervous System and Their Impact on the Remyelination Failure. | Scalabrino G | β | 2022 | β |
| No evidence for intervention-associated DNA methylation changes in monocytes of patients with posttraumatic stress disorder. | Hummel E et al. | β | 2022 | β |
| Non-canonical bivalent H3K4me3K9me3 recognition by Spindlin1/C11orf84 complex. | Du Y et al. | β | 2022 | β |
| NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition. | Drosos Y et al. | β | 2022 | β |
| NSD2 as a Promising Target in Hematological Disorders. | Azagra A et al. | β | 2022 | β |
| Obesity, the other pandemic: linking diet and carcinogenesis by epigenetic mechanisms. | Izquierdo-Torres E et al. | β | 2022 | β |
| Optical Imaging of Epigenetic Modifications in Cancer: A Systematic Review. | Du Y et al. | β | 2022 | β |
| Optimization of synthetic molecular reporters for a mesenchymal glioblastoma transcriptional program by integer programing. | Breitenbach T et al. | β | 2022 | β |
| Optochemical Control of TET Dioxygenases Enables Kinetic Insights into the Domain-Dependent Interplay of TET1 and MBD1 while Oxidizing and Reading 5-Methylcytosine. | Lin TC et al. | β | 2022 | β |
| Parental High-Fat High-Sugar Diet Intake Programming Inflammatory and Oxidative Parameters of Reproductive Health in Male Offspring. | Sertorio MN et al. | β | 2022 | β |
| Parkinson's disease-associated, sex-specific changes in DNA methylation at PARK7 (DJ-1), SLC17A6 (VGLUT2), PTPRN2 (IA-2Ξ²), and NR4A2 (NURR1) in cortical neurons. | Kochmanski J et al. | β | 2022 | β |
| PARP1: Liaison of Chromatin Remodeling and Transcription. | Zong W et al. | β | 2022 | β |
| Peroxisome proliferator-activated receptor gamma coactivator 1-alpha protects a fibrotic liver from partial hepatectomy-induced advanced liver injury through regulating cell cycle arrest. | Zhang L et al. | β | 2022 | β |
| Pharmacoepigenetics of hypertension: genome-wide methylation analysis of responsiveness to four classes of antihypertensive drugs using a double-blind crossover study design. | Nuotio ML et al. | β | 2022 | β |
| PIWI-Interacting RNA (piRNA) and Epigenetic Editing in Environmental Health Sciences. | Perera BPU et al. | β | 2022 | β |
| Polycomb Repressive Complexes: Shaping Pancreatic Beta-Cell Destiny in Development and Metabolic Disease. | Varghese SS et al. | β | 2022 | β |
| PRC1-mediated epigenetic programming is required to generate the ovarian reserve. | Hu M et al. | β | 2022 | β |
| Predicting Response to Neoadjuvant Therapy in Oesophageal Adenocarcinoma. | Jiang W et al. | β | 2022 | β |
| Preliminary Study on the Sequencing of Whole Genomic Methylation and Transcriptome-Related Genes in Thyroid Carcinoma. | Iqbal MA et al. | β | 2022 | β |
| Probing the Interaction Between Chromatin and Chromatin-Associated Complexes with Optical Tweezers. | Leicher R et al. | β | 2022 | β |
| Regulating the regulator: a survey of mechanisms from transcription to translation controlling expression of mammalian cell cycle kinase Aurora A. | Cacioppo R et al. | β | 2022 | β |
| Regulatory chromatin rewiring promotes metabolic switching during adaptation to oncogenic receptor tyrosine kinase inhibition. | Ogden S et al. | β | 2022 | β |
| RINGs, DUBs and Abnormal Brain Growth-Histone H2A Ubiquitination in Brain Development and Disease. | Doyle LA et al. | β | 2022 | β |
| RNA methylation in immune cells. | Chen Y et al. | β | 2022 | β |
| Role of Chromatin Replication in Transcriptional Plasticity, Cell Differentiation and Disease. | LΓ³pez-JimΓ©nez E et al. | β | 2022 | β |
| RPA1 controls chromatin architecture and maintains lipid metabolic homeostasis. | Yin Q et al. | β | 2022 | β |
| Simultaneous Dual-Site Identification of 5<sup>m</sup>C/8<sup>o</sup>G in DNA Triplex Using a Nanopore Sensor. | Li W et al. | β | 2022 | β |
| Single cell cancer epigenetics. | Casado-Pelaez M et al. | β | 2022 | β |
| Small molecule inhibitors targeting the cancers. | Liu GH et al. | β | 2022 | β |
| SOX2 transcription factor binding and function. | Hagey DW et al. | β | 2022 | β |
| Spatially resolved epigenomic profiling of single cells in complex tissues. | Lu T et al. | β | 2022 | β |
| Species-specific chromatin landscape determines how transposable elements shape genome evolution. | Huang Y et al. | β | 2022 | β |
| Stable isotope tracing inΒ vivo reveals a metabolic bridge linking the microbiota to host histone acetylation. | Lund PJ et al. | β | 2022 | β |
| SUMOylation of linker histone H1 drives chromatin condensation and restriction of embryonic cell fate identity. | Sheban D et al. | β | 2022 | β |
| SUV39H1 regulates corneal epithelial wound healing via H3K9me3-mediated repression of p27. | Yang S et al. | β | 2022 | β |
| Targeting Epigenetic Regulatory Enzymes for Cancer Therapeutics: Novel Small-Molecule Epidrug Development. | Jin Y et al. | β | 2022 | β |
| Targets of histone H3 lysine 9 methyltransferases. | Levinsky AJ et al. | β | 2022 | β |
| Temporal signaling, population control, and information processing through chromatin-mediated gene regulation. | Mukund A et al. | β | 2022 | β |
| Temporal variation in DNA methylation during gonadal development in a reptile with temperature-dependent sex determinationβ . | Liu F et al. | β | 2022 | β |
| The Current State of Chromatin Immunoprecipitation (ChIP) from FFPE Tissues. | Amatori S et al. | β | 2022 | β |
| The JMJD Family Histone Demethylases in Crosstalk Between Inflammation and Cancer. | Yang J et al. | β | 2022 | β |
| The Methylation Game: Epigenetic and Epitranscriptomic Dynamics of 5-Methylcytosine. | Alagia A et al. | β | 2022 | β |
| The missing heritability in type 1 diabetes. | Pang H et al. | β | 2022 | β |
| The multifaceted role of micronuclei in tumour progression: A whole organism perspective. | Guscott M et al. | β | 2022 | β |
| The past, present, and future of chemotherapy with a focus on individualization of drug dosing. | DeRidder L et al. | β | 2022 | β |
| The pathogenesis of amyotrophic lateral sclerosis: Mitochondrial dysfunction, protein misfolding and epigenetics. | Chen W et al. | β | 2022 | β |
| The Potential Role of m<sup>6</sup>A in the Regulation of TBI-Induced BGA Dysfunction. | Huang P et al. | β | 2022 | β |
| Therapeutic potential of inhibiting histone 3 lysine 27 demethylases: a review of the literature. | Abu-Hanna J et al. | β | 2022 | β |
| Therapeutic targets for cardiac fibrosis: from old school to next-gen. | Travers JG et al. | β | 2022 | β |
| The role of RNA modification in hepatocellular carcinoma. | Feng Q et al. | β | 2022 | β |
| The Role of Ten-Eleven Translocation Proteins in Inflammation. | Gerecke C et al. | β | 2022 | β |
| The roles of the circadian hormone melatonin in drug addiction. | Jia S et al. | β | 2022 | β |
| The Yin and Yang of epigenetics in the field of nanoparticles. | Musolino E et al. | β | 2022 | β |
| Time Domains of Hypoxia Responses and -Omics Insights. | Yu JJ et al. | β | 2022 | β |
| Toxicoepigenetics for Risk Assessment: Bridging the Gap Between Basic and Regulatory Science. | Le Goff A et al. | β | 2022 | β |
| Transcription-coupled and epigenome-encoded mechanisms direct H3K4 methylation. | Oya S et al. | β | 2022 | β |
| Transcription factors specifically control change. | Rothenberg EV | β | 2022 | β |
| Transcription of rRNA in early mouse embryos promotes chromatin reorganization and expression of major satellite repeats. | Chebrout M et al. | β | 2022 | β |
| Transcription suppression is mediated by the HDAC1-Sin3 complex in Xenopus nucleoplasmic extract. | Quaas CE et al. | β | 2022 | β |
| Transcriptomics, regulatory syntax, and enhancer identification in mesoderm-induced ESCs at single-cell resolution. | Khateb M et al. | β | 2022 | β |
| Unraveling the role of epigenetic regulation in asymmetric cell division during plant development. | Alejo-Vinogradova MT et al. | β | 2022 | β |
| When the "satisficing" is the new "fittest": how a proscriptive definition of adaptation can change our view of cognition and culture. | Magnon V et al. | β | 2022 | β |
| YAP induces an oncogenic transcriptional program through TET1-mediated epigenetic remodeling in liver growth and tumorigenesis. | Wu BK et al. | β | 2022 | β |
| Analysis of Il36a induction by C/EBPΞ² via a half-CREβ’C/EBP element in murine macrophages in dependence of its CpG methylation level. | Nerlich A et al. | β | 2021 | β |
| Approaches to Study Native Chromatin-Modifying Complex Activities and Functions. | Galloy M et al. | β | 2021 | β |
| Are Interactions between Epicardial Adipose Tissue, Cardiac Fibroblasts and Cardiac Myocytes Instrumental in Atrial Fibrosis and Atrial Fibrillation? | Krishnan A et al. | β | 2021 | β |
| Critical Role of Gut Microbiota and Epigenetic Factors in the Pathogenesis of BehΓ§et's Disease. | Ma X et al. | β | 2021 | β |
| Decoding the function of bivalent chromatin in development and cancer. | Kumar D et al. | β | 2021 | β |
| Deposition Bias of Chromatin Proteins Inverts under DNA Replication Stress Conditions. | Zwinderman MRH et al. | β | 2021 | β |
| DNA Methylation and Schizophrenia: Current Literature and Future Perspective. | Magwai T et al. | β | 2021 | β |
| Effect of Cold Atmospheric Plasma on Epigenetic Changes, DNA Damage, and Possibilities for Its Use in Synergistic Cancer Therapy. | BranΓ½ D et al. | β | 2021 | β |
| Epigenetic, Metabolic, and Immune Crosstalk in Germinal-Center-Derived B-Cell Lymphomas: Unveiling New Vulnerabilities for Rational Combination Therapies. | Serganova I et al. | β | 2021 | β |
| Epigenetic modulation of selected immune response genes and altered functions of T lymphocytes and macrophages collectively contribute to autoimmune diabetes protection. | Jayaraman A et al. | β | 2021 | β |
| Epigenetic Regulations of Microglia/Macrophage Polarization in Ischemic Stroke. | Qiu M et al. | β | 2021 | β |
| Epigenetic Regulatory Dynamics in Models of Methamphetamine-Use Disorder. | Jayanthi S et al. | β | 2021 | β |
| Evolutionary epigenomic analyses in mammalian early embryos reveal species-specific innovations and conserved principles of imprinting. | Lu X et al. | β | 2021 | β |
| EZH1/2 inhibition augments the anti-tumor effects of sorafenib in hepatocellular carcinoma. | Kusakabe Y et al. | β | 2021 | β |
| Functional human genes typically exhibit epigenetic conservation. | Rud D et al. | β | 2021 | β |
| Gene Therapy "Made in Germany": A Historical Perspective, Analysis of the Status Quo, and Recommendations for Action by the German Society for Gene Therapy. | BΓΌning H et al. | β | 2021 | β |
| Genetic screen for suppressors of increased silencing in rpd3 mutants in Saccharomyces cerevisiae identifies a potential role for H3K4 methylation. | Kleinschmidt RA et al. | β | 2021 | β |
| H3K9 Methyltransferases Suv39h1 and Suv39h2 Control the Differentiation of Neural Progenitor Cells in the Adult Hippocampus. | Guerra MV et al. | β | 2021 | β |
| HAP2-Mediated Gamete Fusion: Lessons From the World of Unicellular Eukaryotes. | Pinello JF et al. | β | 2021 | β |
| Histone H1 Mutations in Lymphoma: A Link(er) between Chromatin Organization, Developmental Reprogramming, and Cancer. | Soshnev AA et al. | β | 2021 | β |
| Host Immune-Metabolic Adaptations Upon Mycobacterial Infections and Associated Co-Morbidities. | Llibre A et al. | β | 2021 | β |
| How a cell decides its own fate: a single-cell view of molecular mechanisms and dynamics of cell-type specification. | Mircea M et al. | β | 2021 | β |
| <i>Cis</i>-Acting Factors Causing Secondary Epimutations: Impact on the Risk for Cancer and Other Diseases. | Ruiz de la Cruz M et al. | β | 2021 | β |
| Immune and Epigenetic Pathways Linking Childhood Adversity and Health Across the Lifespan. | Chen MA et al. | β | 2021 | β |
| Integration of Epigenetic Mechanisms into Non-Genotoxic Carcinogenicity Hazard Assessment: Focus on DNA Methylation and Histone Modifications. | Desaulniers D et al. | β | 2021 | β |
| Interplay Among Metabolism, Epigenetic Modifications, and Gene Expression in Cancer. | Huo M et al. | β | 2021 | β |
| Interplay Between BALL and CREB Binding Protein Maintains H3K27 Acetylation on Active Genes in <i>Drosophila</i>. | Shaukat A et al. | β | 2021 | β |
| Intersection of Epigenetic and Immune Alterations: Implications for Fetal Alcohol Spectrum Disorder and Mental Health. | Lussier AA et al. | β | 2021 | β |
| Is There a Histone Code for Cellular Quiescence? | Bonitto K et al. | β | 2021 | β |
| Mechanism and Therapeutic Opportunities of Histone Modifications in Chronic Liver Disease. | Cai Q et al. | β | 2021 | β |
| Metabolic Fuel for Epigenetic: Nuclear Production Meets Local Consumption. | Boon R | β | 2021 | β |
| Multiomic biological approaches to the study of child abuse and neglect. | Layfield SD et al. | β | 2021 | β |
| New Design Rules for Developing Potent Cell-Active Inhibitors of the Nucleosome Remodeling Factor (NURF) via BPTF Bromodomain Inhibition. | Zahid H et al. | β | 2021 | β |
| Non-Cell Autonomous and Epigenetic Mechanisms of Huntington's Disease. | Kim C et al. | β | 2021 | β |
| O-GlcNAcylation links oncogenic signals and cancer epigenetics. | Sun L et al. | β | 2021 | β |
| Recent Discoveries in Epigenetic Modifications of Polycystic Kidney Disease. | Bowden SA et al. | β | 2021 | β |
| Role of Mitochondria in Radiation Responses: Epigenetic, Metabolic, and Signaling Impacts. | Averbeck D et al. | β | 2021 | β |
| Sigmatropic Rearrangements of Polymer Backbones: Vinyl Polymers from Polyesters in One Step. | Ditzler RAJ et al. | β | 2021 | β |
| Subtelomeric Chromatin in the Fission Yeast <i>S. pombe</i>. | Yadav RK et al. | β | 2021 | β |
| Targeting Epigenetic Mechanisms to Treat Alcohol Use Disorders (AUD). | Rodriguez FD | β | 2021 | β |
| Tau Stabilizes Chromatin Compaction. | Rico T et al. | β | 2021 | β |
| The 3D Genome: From Structure to Function. | Mohanta TK et al. | β | 2021 | β |
| The Clock Takes Shape-24Β h Dynamics in Genome Topology. | Tartour K et al. | β | 2021 | β |
| The existence of a nonclassical TCA cycle in the nucleus that wires the metabolic-epigenetic circuitry. | Liu X et al. | β | 2021 | β |
| The Potential Role of Genetics, Environmental Factors, and Gut Dysbiosis in the Aberrant Non-Coding RNA Expression to Mediate Inflammation and Osteoclastogenic/Osteogenic Differentiation in Ankylosing Spondylitis. | Liao HT et al. | β | 2021 | β |
| Trichostatin A Relieves Growth Suppression and Restores Histone Acetylation at Specific Sites in a FUS ALS/FTD Yeast Model. | Bennett SA et al. | β | 2021 | β |
| Yersinia remodels epigenetic histone modifications in human macrophages. | Bekere I et al. | β | 2021 | β |