LS-SNP/PDB: annotated non-synonymous SNPs mapped to Protein Data Bank structures.
paper
Cited
Public
Unavailable
- Authors
- Ryan, Michael; Diekhans, Mark; Lien, Stephanie; Liu, Yun; Karchin, Rachel
- Year
- 2009
- Journal
- Bioinformatics (Oxford, England)
- PMID
- 19369493
- DOI
- 10.1093/bioinformatics/btp242
- PMCID
- PMC6276889
SUMMARY: LS-SNP/PDB is a new WWW resource for genome-wide annotation of human non-synonymous (amino acid changing) SNPs. It serves high-quality protein graphics rendered with UCSF Chimera molecular visualization software. The system is kept up-to-date by an automated, high-throughput build pipeline that systematically maps human nsSNPs onto Protein Data Bank structures and annotates several biologically relevant features. AVAILABILITY: LS-SNP/PDB is available at (http://ls-snp.icm.jhu.edu/ls-snp-pdb) and via links from protein data bank (PDB) biology and chemistry tabs, UCSC Genome Browser Gene Details and SNP Details pages and PharmGKB Gene Variants Downloads/Cross-References pages.
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