siRNA drug

Aliases

CtBP2 targeted siRNA, TBC1D5 siRNA, siRNA-silenced, small interfering RNA

External links

DrugBank · PubChem

Related entities (5)

Mentioned in (50)

Papers in which this entity is mentioned.

• Single-cell exon deletion profiling reveals splicing events that shape gene expression and cell state dynamics. (2026)
• FET fusion oncoproteins disrupt physiologic DNA repair and create a targetable opportunity for ATR inhibitor therapy. (2025)
• Tumour-wide RNA splicing aberrations generate actionable public neoantigens. (2025)
• Epsin Nanotherapy Regulates Cholesterol Transport to Fortify Atheroma Regression. (2023)
• Towards understandings of serine/arginine-rich splicing factors. (2023)
• A novel missense variant in ACAA1 contributes to early-onset Alzheimer's disease, impairs lysosomal function, and facilitates amyloid-β pathology and cognitive decline. (2021)
• Choline Kinase: An Unexpected Journey for a Precision Medicine Strategy in Human Diseases. (2021)
• Simultaneous epigenetic perturbation and genome imaging reveal distinct roles of H3K9me3 in chromatin architecture and transcription. (2020)
• Gene Expression in Patient-Derived Neural Progenitors Implicates WNT5A Signaling in the Etiology of Schizophrenia. (2020)
• Genetic compensation triggered by mutant mRNA degradation. (2019)
• Alternative Lengthening of Telomeres through Two Distinct Break-Induced Replication Pathways. (2019)
• Inhibition of TBC1D5 activates Rab7a and can enhance the function of the retromer cargo-selective complex. (2018)
• OncoKB: A Precision Oncology Knowledge Base. (2017)
• Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma. (2017)
• A role for human homologous recombination factors in suppressing microhomology-mediated end joining. (2016)
• The cell cycle regulator CCDC6 is a key target of RNA-binding protein EWS. (2015)
• EWS and FUS bind a subset of transcribed genes encoding proteins enriched in RNA regulatory functions. (2015)
• BET inhibitors induce apoptosis through a MYC independent mechanism and synergise with CDK inhibitors to kill osteosarcoma cells. (2015)
• CtBP2 is an independent prognostic marker that promotes GLI1 induced epithelial-mesenchymal transition in hepatocellular carcinoma. (2015)
• Position-specific binding of FUS to nascent RNA regulates mRNA length. (2015)
• Moderate prenatal alcohol exposure enhances GluN2B containing NMDA receptor binding and ifenprodil sensitivity in rat agranular insular cortex. (2015)
• Condensins are Required for Maintenance of Nuclear Architecture. (2014)
• An atlas of active enhancers across human cell types and tissues. (2014)
• MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens. (2014)
• PVT1 dependence in cancer with MYC copy-number increase. (2014)
• Mitogen-activated protein kinase modulates ethanol inhibition of cell adhesion mediated by the L1 neural cell adhesion molecule. (2013)
• RNA splicing: a new player in the DNA damage response. (2013)
• ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia. (2012)
• Alpha4 subunit-containing GABAA receptors in the accumbens shell contribute to the reinforcing effects of alcohol. (2012)
• Emerging role of non-coding RNA in neural plasticity, cognitive function, and neuropsychiatric disorders. (2012)
• Maternal immune activation by LPS selectively alters specific gene expression profiles of interneuron migration and oxidative stress in the fetus without triggering a fetal immune response. (2012)
• Receptor heteromerization expands the repertoire of cannabinoid signaling in rodent neurons. (2012)
• Regulation of ethanol-sensitive EAAT2 expression through adenosine A1 receptor in astrocytes. (2011)
• Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma. (2011)
• Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43. (2011)
• ViennaRNA Package 2.0. (2011)
• MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins. (2011)
• Apolipoprotein E: from lipid transport to neurobiology. (2011)
• AT1R-CB₁R heteromerization reveals a new mechanism for the pathogenic properties of angiotensin II. (2011)
• Molecular mechanisms of long noncoding RNAs. (2011)
• Long noncoding RNAs with enhancer-like function in human cells. (2010)
• The opposite effects of acute and chronic alcohol on lipopolysaccharide-induced inflammation are linked to IRAK-M in human monocytes. (2009)
• The epigenetics of sex differences in the brain. (2009)
• DNA methylation and methyl-CpG binding proteins: developmental requirements and function. (2009)
• Cancer-specific high-throughput annotation of somatic mutations: computational prediction of driver missense mutations. (2009)
• Distinct function of 2 chromatin remodeling complexes that share a common subunit, Williams syndrome transcription factor (WSTF). (2009)
• Ethanol inhibits neuronal differentiation by disrupting activity-dependent neuroprotective protein signaling. (2008)
• Repression of smoothened by patched-dependent (pro-)vitamin D3 secretion. (2006)
• Akt phosphorylation of p300 at Ser-1834 is essential for its histone acetyltransferase and transcriptional activity. (2005)
• Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferation. (2005)

Merged raw entities (5)

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