IL-6 drug
Evidence from:
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all sources
Related entities (11)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| ABO | associated_with | IL-6 | — | 1 |
| AN | associated_with | IL-6 | — | 1 |
| antagonism | associated_with | IL-6 | — | 1 |
| IFN-γ | regulates | IL-6 | — | 1 |
| IL-6 | protective_against | Amyloid beta | — | 1 |
| IL-6 | expressed_in | hippocampus | — | 1 |
| IL-6 | biomarker_for | inflammation | — | 1 |
| IL-6 | regulates | motor cortex | — | 1 |
| IL-6 | protective_against | RXR | — | 1 |
| LPS | regulates | IL-6 | — | 1 |
| RXR | regulates | IL-6 | — | 1 |
Mentioned in (88)
Papers in which this entity is mentioned.
- Maternal and child immune profiles are associated with neurometabolite measures of early-life neuroinflammation in children who are HIV-exposed and uninfected: a South African birth cohort. (2025)
- Chromosomal instability as a driver of cancer progression. (2025)
- Maternal and child immune profiles are associated with neurometabolite measures of early-life neuroinflammation in children who are HIV-exposed and uninfected: a South African birth cohort. (2025)
- Splicing neoantigen discovery with SNAF reveals shared targets for cancer immunotherapy. (2024)
- Oral supplementation of choline attenuates the development of alcohol-related liver disease (ALD). (2024)
- Desmoplastic stromal signatures predict patient outcomes in pancreatic ductal adenocarcinoma. (2023)
- Pathogenesis of Alcoholic Fatty Liver a Narrative Review. (2023)
- An overview of DNA methylation-derived trait score methods and applications. (2023)
- Altered dendritic morphology in dorsolateral prefrontal cortex of nonhuman primates prenatally exposed to maternal immune activation. (2023)
- Multiomic prioritisation of risk genes for anorexia nervosa. (2023)
- Osteoclasts in Osteosarcoma: Mechanisms, Interactions, and Therapeutic Prospects. (2023)
- Alcohol and Immunology: Mechanisms of multi-organ damage. Summary of the 2022 alcohol and Immunology research interest group (AIRIG) meeting. (2023)
- Lack of Evidence for a Relationship Between Salivary CRP and Women's Sexual Desire: An Investigation Across Clinical and Healthy Samples. (2022)
- Detection and characterization of lung cancer using cell-free DNA fragmentomes. (2021)
- Inflammatory modulation of the associations between prenatal maternal depression and neonatal brain. (2021)
- Canonical TGF-β signaling regulates the relationship between prenatal maternal depression and amygdala development in early life. (2021)
- Choline Kinase: An Unexpected Journey for a Precision Medicine Strategy in Human Diseases. (2021)
- Macrophage Polarization States in the Tumor Microenvironment. (2021)
- gene network in the prefrontal cortex is associated with total brain volume in childhood. (2020)
- B cells and tertiary lymphoid structures promote immunotherapy response. (2020)
- Immune network dysregulation associated with child neurodevelopmental delay: modulatory role of prenatal alcohol exposure. (2020)
- Murine Models for the Study of Fetal Alcohol Spectrum Disorders: An Overview. (2020)
- Single-cell RNA landscape of intratumoral heterogeneity and immunosuppressive microenvironment in advanced osteosarcoma. (2020)
- Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations. (2020)
- Relationship of prenatal maternal obesity and diabetes to offspring neurodevelopmental and psychiatric disorders: a narrative review. (2020)
- Prenatal Developmental Origins of Future Psychopathology: Mechanisms and Pathways. (2019)
- Peripheral Biomarkers for First-Episode Psychosis-Opportunities from the Neuroinflammatory Hypothesis of Schizophrenia. (2019)
- Prenatal Stress and Maternal Immune Dysregulation in Autism Spectrum Disorders: Potential Points for Intervention. (2019)
- Detection of local and remote cellular damage caused by spinal cord and peripheral nerve injury using a heat shock signaling reporter system. (2018)
- Implications of altered maternal cytokine concentrations on infant outcomes in children with prenatal alcohol exposure. (2018)
- Altered maternal immune networks are associated with adverse child neurodevelopment: Impact of alcohol consumption during pregnancy. (2018)
- PI3K Signaling in Neurons: A Central Node for the Control of Multiple Functions. (2018)
- Immune Dysfunction and Autoimmunity as Pathological Mechanisms in Autism Spectrum Disorders. (2018)
- Effects of early-life adversity on immune function are mediated by prenatal environment: Role of prenatal alcohol exposure. (2017)
- Demystifying the cytokine network: Mathematical models point the way. (2017)
- Neonatal Cytokine Profiles Associated With Autism Spectrum Disorder. (2017)
- Cerebral organoids reveal early cortical maldevelopment in schizophrenia-computational anatomy and genomics, role of FGFR1. (2017)
- Maternal choline supplementation during murine pregnancy modulates placental markers of inflammation, apoptosis and vascularization in a fetal sex-dependent manner. (2017)
- Autism with intellectual disability is associated with increased levels of maternal cytokines and chemokines during gestation. (2017)
- The effect of alcohol on the differential expression of cluster of differentiation 14 gene, associated pathways, and genetic network. (2017)
- Effect of Neuroinflammation on Synaptic Organization and Function in the Developing Brain: Implications for Neurodevelopmental and Neurodegenerative Disorders. (2017)
- Lower total and regional grey matter brain volumes in youth with perinatally-acquired HIV infection: Associations with HIV disease severity, substance use, and cognition. (2017)
- Fetal sex is associated with maternal stimulated cytokine production, but not serum cytokine levels, in human pregnancy. (2017)
- Evidence for an immune signature of prenatal alcohol exposure in female rats. (2016)
- B lymphocytes and cancer: a love-hate relationship. (2016)
- Efficient derivation of microglia-like cells from human pluripotent stem cells. (2016)
- The Placenta as a Mediator of Stress Effects on Neurodevelopmental Reprogramming. (2016)
- Small molecule inhibition of cAMP response element binding protein in human acute myeloid leukemia cells. (2016)
- Direct Transcriptional Effects of Apolipoprotein E. (2016)
- Vitamin D and Reproduction: From Gametes to Childhood. (2015)
- Fetal sex-based differences in maternal hormones, angiogenic factors, and immune mediators during pregnancy and the postpartum period. (2015)
- A review of the nonpressor and nonantidiuretic actions of the hormone vasopressin. (2015)
- Impact of prenatal environmental stress on cortical development. (2015)
- Identification of cytokine-induced modulation of microRNA expression and secretion as measured by a novel microRNA specific qPCR assay. (2015)
- Regulation of calcitriol biosynthesis and activity: focus on gestational vitamin D deficiency and adverse pregnancy outcomes. (2015)
- The association of cord serum cytokines with neurodevelopmental outcomes. (2015)
- Activation of the FGFR-STAT3 pathway in breast cancer cells induces a hyaluronan-rich microenvironment that licenses tumor formation. (2014)
- Neuroinflammation and M2 microglia: the good, the bad, and the inflamed. (2014)
- Neonatal cytokines and chemokines and risk of Autism Spectrum Disorder: the Early Markers for Autism (EMA) study: a case-control study. (2014)
- Plasma cytokine profiling in sibling pairs discordant for autism spectrum disorder. (2013)
- Interleukin-6 (IL-6) receptor/IL-6 fusion protein (Hyper IL-6) effects on the neonatal mouse brain: possible role for IL-6 trans-signaling in brain development and functional neurobehavioral outcomes. (2013)
- Effects of alcohol on the endocrine system. (2013)
- A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains. (2013)
- Thalidomide-a notorious sedative to a wonder anticancer drug. (2013)
- In vivo and in vitro effects of an apolipoprotein e mimetic peptide on amyloid-β pathology. (2013)
- Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases. (2012)
- Myeloid cells in tumor inflammation. (2012)
- Oncostatin M decreases interleukin-1 β secretion by human synovial fibroblasts and attenuates an acute inflammatory reaction in vivo. (2012)
- Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (2012)
- Regulation of cancer progression by β-endorphin neuron. (2012)
- Maternal immune activation by LPS selectively alters specific gene expression profiles of interneuron migration and oxidative stress in the fetus without triggering a fetal immune response. (2012)
- Retinoic acid production by endocardium and epicardium is an injury response essential for zebrafish heart regeneration. (2011)
- Personality and obesity across the adult life span. (2011)
- Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome. (2011)
- Increased midgestational IFN-γ, IL-4 and IL-5 in women bearing a child with autism: A case-control study. (2011)
- Neuronal LRP1 knockout in adult mice leads to impaired brain lipid metabolism and progressive, age-dependent synapse loss and neurodegeneration. (2010)
- COG1410, an apolipoprotein E-based peptide, improves cognitive performance and reduces cortical loss following moderate fluid percussion injury in the rat. (2010)
- Novel roles for immune molecules in neural development: implications for neurodevelopmental disorders. (2010)
- Cellular metabolic stress: considering how cells respond to nutrient excess. (2010)
- Role of microglia in ethanol's apoptotic action on hypothalamic neuronal cells in primary cultures. (2010)
- The plausibility of maternal nutritional status being a contributing factor to the risk for fetal alcohol spectrum disorders: the potential influence of zinc status as an example. (2010)
- Peroxisome proliferator-activated receptor and retinoic x receptor in alcoholic liver disease. (2009)
- Neurotoxic effects and biomarkers of lead exposure: a review. (2009)
- Adrenomedullin signaling is necessary for murine lymphatic vascular development. (2008)
- Maternal immune activation alters fetal brain development through interleukin-6. (2007)
- Estrogen inhibits GH signaling by suppressing GH-induced JAK2 phosphorylation, an effect mediated by SOCS-2. (2003)
- C-reactive protein: a critical update. (2003)
- Pituitary adenylate cyclase-activating polypeptide protects rat cerebellar granule neurons against ethanol-induced apoptotic cell death. (2002)
Merged raw entities (3)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| il-6 | drug | 80 | 280 |
| interleukin-6 | drug | 19 | 35 |
| interleukin 6 | drug | 3 | 3 |