SAG drug
Evidence from:
primary |
all sources
Related entities (7)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| acute stress | associated_with | SAG | 0.05 | 1 |
| acute stress | regulates | SAG | — | 1 |
| DAGLA | regulates | SAG | — | 1 |
| phospholipase C | regulates | SAG | — | 1 |
| SAG | regulates | 2-AG | — | 1 |
| SAG | expressed_in | BLA | — | 1 |
| SAG | associated_with | KSR medium | — | 1 |
Mentioned in (20)
Papers in which this entity is mentioned.
- Multi-omic quantitative trait loci link tandem repeat size variation to gene regulation in human brain. (2025)
- Human 3D brain organoids: steering the demolecularization of brain and neurological diseases. (2023)
- Gene-alcohol interactions in birth defects. (2023)
- Variation in phenotypes from a Bmp-Gata3 genetic pathway is modulated by Shh signaling. (2021)
- Transcriptome-Wide Regulation of Key Developmental Pathways in the Mouse Neural Tube by Prenatal Alcohol Exposure. (2020)
- Cannabinoids Exacerbate Alcohol Teratogenesis by a CB1-Hedgehog Interaction. (2019)
- Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector. (2018)
- Assembly of functionally integrated human forebrain spheroids. (2017)
- Preaxial polydactyly following early gestational exposure to the smoothened agonist, SAG, in C57BL/6J mice. (2017)
- Smoothened determines β-arrestin-mediated removal of the G protein-coupled receptor Gpr161 from the primary cilium. (2016)
- Chronic up-regulation of sonic hedgehog has little effect on postnatal craniofacial morphology of euploid and trisomic mice. (2016)
- Endocannabinoids are conserved inhibitors of the Hedgehog pathway. (2015)
- Acute upregulation of hedgehog signaling in mice causes differential effects on cranial morphology. (2015)
- Direct functional consequences of ZRS enhancer mutation combine with secondary long range SHH signalling effects to cause preaxial polydactyly. (2014)
- Size does not always matter: Ts65Dn Down syndrome mice show cerebellum-dependent motor learning deficits that cannot be rescued by postnatal SAG treatment. (2013)
- Hedgehog agonist therapy corrects structural and cognitive deficits in a Down syndrome mouse model. (2013)
- A small-molecule smoothened agonist prevents glucocorticoid-induced neonatal cerebellar injury. (2011)
- Sonic hedgehog signaling is decoded by calcium spike activity in the developing spinal cord. (2011)
- Repeated homotypic stress elevates 2-arachidonoylglycerol levels and enhances short-term endocannabinoid signaling at inhibitory synapses in basolateral amygdala. (2009)
- Small molecule modulation of Smoothened activity. (2002)
Merged raw entities (3)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| sag | drug | 19 | 248 |
| smoothened agonist | drug | 3 | 4 |
| stearoyl arachidonoyl glycerol | drug | — | — |