RB1 gene

Aliases

Rb, retinoblastoma protein

External links

NCBI Gene · Ensembl · GeneCards · UniProt

Related entities (1)

Mentioned in (68)

Papers in which this entity is mentioned.

• Investigation of a global mouse methylome atlas reveals subtype-specific copy number alterations in pediatric cancer models. (2026)
• Whole-genome landscapes of 1,364 breast cancers. (2026)
• Whole genome sequencing approach to assess homologous recombination deficiency in a pan-cancer cohort. (2026)
• Multigenerational cell tracking of DNA replication and heritable DNA damage. (2025)
• Chromosomal instability as a driver of cancer progression. (2025)
• Synchronized long-read genome, methylome, epigenome and transcriptome profiling resolve a Mendelian condition. (2025)
• Splicing neoantigen discovery with SNAF reveals shared targets for cancer immunotherapy. (2024)
• Insights for precision oncology from the integration of genomic and clinical data of 13,880 tumors from the 100,000 Genomes Cancer Programme. (2024)
• Heritable defects in telomere and mitotic function selectively predispose to sarcomas. (2023)
• Combined low-pass whole genome and targeted sequencing in liquid biopsies for pediatric solid tumors. (2023)
• Osteoclasts in Osteosarcoma: Mechanisms, Interactions, and Therapeutic Prospects. (2023)
• Construction and validation of a novel gene signature for predicting the prognosis of osteosarcoma. (2022)
• Circulating Tumor DNA Is Associated with Response and Survival in Patients with Advanced Leiomyosarcoma. (2022)
• Integrating molecular profiles into clinical frameworks through the Molecular Oncology Almanac to prospectively guide precision oncology. (2021)
• Prospective pan-cancer germline testing using MSK-IMPACT informs clinical translation in 751 patients with pediatric solid tumors. (2021)
• Integrated Genomic Analysis Identifies Driver Genes and Cisplatin-Resistant Progenitor Phenotype in Pediatric Liver Cancer. (2021)
• Biologically informed deep neural network for prostate cancer discovery. (2021)
• Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes. (2021)
• Immuno-genomic landscape of osteosarcoma. (2020)
• Pan-cancer analysis of whole genomes. (2020)
• Comprehensive germline genomic profiles of children, adolescents and young adults with solid tumors. (2020)
• Provocative questions in osteosarcoma basic and translational biology: A report from the Children's Oncology Group. (2019)
• The Clonal Evolution of Metastatic Osteosarcoma as Shaped by Cisplatin Treatment. (2019)
• Whole-genome sequencing of triple-negative breast cancers in a population-based clinical study. (2019)
• VCF2CNA: A tool for efficiently detecting copy-number alterations in VCF genotype data and tumor purity. (2019)
• Germline variants associated with leukocyte genes predict tumor recurrence in breast cancer patients. (2019)
• Genome-Informed Targeted Therapy for Osteosarcoma. (2019)
• Pan-cancer whole-genome analyses of metastatic solid tumours. (2019)
• Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours. (2018)
• Genome doubling shapes the evolution and prognosis of advanced cancers. (2018)
• The Immune Landscape of Cancer. (2018)
• Comprehensive Cancer-Predisposition Gene Testing in an Adult Multiple Primary Tumor Series Shows a Broad Range of Deleterious Variants and Atypical Tumor Phenotypes. (2018)
• Tumor fraction in cell-free DNA as a biomarker in prostate cancer. (2018)
• Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes (2018)
• Clinical cancer genomic profiling by three-platform sequencing of whole genome, whole exome and transcriptome. (2018)
• Patterns and mechanisms of structural variations in human cancer. (2018)
• Copy number signatures and mutational processes in ovarian carcinoma. (2018)
• Universal Patterns of Selection in Cancer and Somatic Tissues. (2017)
• Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma. (2017)
• Integrative clustering of multi-level 'omic data based on non-negative matrix factorization algorithm. (2017)
• Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors. (2017)
• PGBD5 promotes site-specific oncogenic mutations in human tumors. (2017)
• Copy-number signatures and mutational processes in ovarian carcinoma (2017)
• Association of germline variants in the APOBEC3 region with cancer risk and enrichment with APOBEC-signature mutations in tumors. (2016)
• Landscape of somatic mutations in 560 breast cancer whole-genome sequences. (2016)
• Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer. (2016)
• Development and clinical application of an integrative genomic approach to personalized cancer therapy. (2016)
• Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets. (2015)
• Integrative clinical genomics of advanced prostate cancer. (2015)
• A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis. (2015)
• Germline Mutations in Predisposition Genes in Pediatric Cancer. (2015)
• Comprehensive genomic profiles of small cell lung cancer. (2015)
• Unraveling the clonal hierarchy of somatic genomic aberrations. (2014)
• Recurrent somatic structural variations contribute to tumorigenesis in pediatric osteosarcoma. (2014)
• Involvement of p53 in the repair of DNA double strand breaks: multifaceted Roles of p53 in homologous recombination repair (HRR) and non-homologous end joining (NHEJ). (2014)
• Cancer genome landscapes. (2013)
• Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. (2013)
• Emerging landscape of oncogenic signatures across human cancers. (2013)
• RNA splicing: a new player in the DNA damage response. (2013)
• Computational approaches to identify functional genetic variants in cancer genomes. (2013)
• The genomic landscape of hypodiploid acute lymphoblastic leukemia. (2013)
• Pan-cancer patterns of somatic copy number alteration. (2013)
• LIN28B promotes growth and tumorigenesis of the intestinal epithelium via Let-7. (2013)
• Molecular genetics of B-precursor acute lymphoblastic leukemia. (2012)
• Detectable clonal mosaicism from birth to old age and its relationship to cancer. (2012)
• The Pediatric Cancer Genome Project. (2012)
• GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers. (2011)
• Integrative analysis of the melanoma transcriptome. (2010)

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