H3K4me3 drug
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Related entities (14)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| astrocytes | associated_with | H3K4me3 | — | 1 |
| chromatin states | associated_with | H3K4me3 | — | 1 |
| genetic variants | associated_with | H3K4me3 | — | 1 |
| H3K4me3 | biomarker_for | alcohol abuse | — | 1 |
| H3K4me3 | biomarker_for | AUDIT-C | — | 1 |
| H3K4me3 | biomarker_for | auditory | — | 1 |
| H3K4me3 | biomarker_for | cocaine | — | 1 |
| H3K4me3 | regulates | Igf1r | — | 1 |
| H3K4me3 | associated_with | pluripotent cells | — | 1 |
| H3K4me3 | regulates | PNOC | — | 1 |
| H3K4me3 | associated_with | Roadmap Epigenomics | — | 1 |
| H3K4me3 | regulates | Slc6a15 | — | 1 |
| Roadmap Epigenomics consortium | associated_with | H3K4me3 | — | 1 |
| spinal cord | associated_with | H3K4me3 | — | 1 |
Mentioned in (88)
Papers in which this entity is mentioned.
- LINE-1 retrotransposons mediate cis-acting transcriptional control in human pluripotent stem cells and regulate early brain development. (2025)
- Tracing the evolution of single-cell 3D genomes in Kras-driven cancers. (2025)
- Nucleotide Transformer: building and evaluating robust foundation models for human genomics. (2025)
- Transcription start sites experience a high influx of heritable variants fueled by early development. (2025)
- Global impact of unproductive splicing on human gene expression. (2024)
- A DNA methylation atlas of normal human cell types. (2023)
- Genetic architecture of 11 major psychiatric disorders at biobehavioral, functional genomic and molecular genetic levels of analysis. (2022)
- Epigenetics in Alzheimer's Disease. (2022)
- Simultaneous epigenetic perturbation and genome imaging reveal distinct roles of H3K9me3 in chromatin architecture and transcription. (2020)
- Neonatal Alcohol Exposure in Mice Induces Select Differentiation- and Apoptosis-Related Chromatin Changes Both Independent of and Dependent on Sex. (2020)
- Functionally informed fine-mapping and polygenic localization of complex trait heritability. (2020)
- Folding Keratin Gene Clusters during Skin Regional Specification. (2020)
- Diverse noncoding mutations contribute to deregulation of cis-regulatory landscape in pediatric cancers. (2020)
- Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits. (2020)
- Genetic compensation triggered by mutant mRNA degradation. (2019)
- Super-enhancers: critical roles and therapeutic targets in hematologic malignancies. (2019)
- Global DNA Methylation and Histone Posttranslational Modifications in Human and Nonhuman Primate Brain in Association with Prenatal Alcohol Exposure. (2019)
- Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations. (2019)
- Epigenetics and depression . (2019)
- Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types. (2018)
- The Gene Encoding Protocadherin 9 (PCDH9), a Novel Risk Factor for Major Depressive Disorder. (2018)
- Ventral striatal regulation of CREM mediates impulsive action and drug addiction vulnerability. (2018)
- Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility. (2018)
- Epigenetic mechanisms in alcohol- and adversity-induced developmental origins of neurobehavioral functioning. (2018)
- TOR complex 2 in fission yeast is required for chromatin-mediated gene silencing and assembly of heterochromatic domains at subtelomeres. (2018)
- Neuroepigenetics and addiction. (2018)
- PI3K Signaling in Neurons: A Central Node for the Control of Multiple Functions. (2018)
- The 3D Genome Browser: a web-based browser for visualizing 3D genome organization and long-range chromatin interactions. (2018)
- Accurate Recycling of Parental Histones Reproduces the Histone Modification Landscape during DNA Replication. (2018)
- Universal Patterns of Selection in Cancer and Somatic Tissues. (2017)
- Network analysis identifies chromosome intermingling regions as regulatory hotspots for transcription. (2017)
- Orthotopic patient-derived xenografts of paediatric solid tumours. (2017)
- DNA replication timing during development anticipates transcriptional programs and parallels enhancer activation. (2017)
- Disconnect between alcohol-induced alterations in chromatin structure and gene transcription in a mouse embryonic stem cell model of exposure. (2017)
- Dysregulation of Cortical Neuron DNA Methylation Profile in Autism Spectrum Disorder. (2017)
- PGBD5 promotes site-specific oncogenic mutations in human tumors. (2017)
- The role of active DNA demethylation and Tet enzyme function in memory formation and cocaine action. (2016)
- The Ensembl gene annotation system. (2016)
- Novel genetic loci underlying human intracranial volume identified through genome-wide association. (2016)
- Nuclear organization and 3D chromatin architecture in cognition and neuropsychiatric disorders. (2016)
- Cause and Consequence of Tethering a SubTAD to Different Nuclear Compartments. (2016)
- Satb2 determines miRNA expression and long-term memory in the adult central nervous system. (2016)
- A hit-and-run heat shock factor governs sustained histone methylation and transcriptional stress memory. (2016)
- Alteration of Gene Expression, DNA Methylation, and Histone Methylation in Free Radical Scavenging Networks in Adult Mouse Hippocampus following Fetal Alcohol Exposure. (2016)
- Tissue-Specific Gene Repositioning by Muscle Nuclear Membrane Proteins Enhances Repression of Critical Developmental Genes during Myogenesis. (2016)
- The PsychENCODE project. (2015)
- Dose-dependent alcohol-induced alterations in chromatin structure persist beyond the window of exposure and correlate with fetal alcohol syndrome birth defects. (2015)
- Genomic influences on alcohol problems in a population-based sample of young adults. (2015)
- Developmental exposure to 50 parts-per-billion arsenic influences histone modifications and associated epigenetic machinery in a region- and sex-specific manner in the adult mouse brain. (2015)
- Epigenomics and the structure of the living genome. (2015)
- Post-translational modifications of histones that influence nucleosome dynamics. (2015)
- A comprehensive view of the epigenetic landscape part I: DNA methylation, passive and active DNA demethylation pathways and histone variants. (2015)
- Prenatal ethanol exposure alters adult hippocampal VGLUT2 expression with concomitant changes in promoter DNA methylation, H3K4 trimethylation and miR-467b-5p levels. (2015)
- The landscape of long noncoding RNAs in the human transcriptome. (2015)
- An atlas of active enhancers across human cell types and tissues. (2014)
- Gene expression in the addicted brain. (2014)
- Distinct structural transitions of chromatin topological domains correlate with coordinated hormone-induced gene regulation. (2014)
- Common DNA methylation alterations in multiple brain regions in autism. (2014)
- Fetal alcohol programming of hypothalamic proopiomelanocortin system by epigenetic mechanisms and later life vulnerability to stress. (2014)
- Long-term genomic and epigenomic dysregulation as a consequence of prenatal alcohol exposure: a model for fetal alcohol spectrum disorders. (2014)
- EWS-FLI1 utilizes divergent chromatin remodeling mechanisms to directly activate or repress enhancer elements in Ewing sarcoma. (2014)
- Fetal alcohol spectrum disorders and their transmission through genetic and epigenetic mechanisms. (2014)
- Gestational choline supplementation normalized fetal alcohol-induced alterations in histone modifications, DNA methylation, and proopiomelanocortin (POMC) gene expression in β-endorphin-producing POMC neurons of the hypothalamus. (2013)
- The sox family of transcription factors: versatile regulators of stem and progenitor cell fate. (2013)
- In utero alcohol exposure, epigenetic changes, and their consequences. (2013)
- Coordinated cell type-specific epigenetic remodeling in prefrontal cortex begins before birth and continues into early adulthood. (2013)
- Alcohol-induced epigenetic alterations to developmentally crucial genes regulating neural stemness and differentiation. (2013)
- Landscape of transcription in human cells. (2012)
- Male germline transmits fetal alcohol adverse effect on hypothalamic proopiomelanocortin gene across generations. (2012)
- Identifying ChIP-seq enrichment using MACS. (2012)
- Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation. (2012)
- Novel mutations target distinct subgroups of medulloblastoma. (2012)
- An integrated encyclopedia of DNA elements in the human genome. (2012)
- Regulation of chromatin by histone modifications. (2011)
- Extensive epigenetic reprogramming in human somatic tissues between fetus and adult. (2011)
- Mechanisms and consequences of alternative polyadenylation. (2011)
- An integrated ChIP-seq analysis platform with customizable workflows. (2011)
- CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing. (2011)
- Molecular and phenotypic aspects of CHD7 mutation in CHARGE syndrome. (2010)
- Histone methylation regulates memory formation. (2010)
- Long noncoding RNAs with enhancer-like function in human cells. (2010)
- Conserved role of intragenic DNA methylation in regulating alternative promoters. (2010)
- A novel and universal method for microRNA RT-qPCR data normalization. (2009)
- Model-based analysis of ChIP-Seq (MACS). (2008)
- Model-based analysis of ChIP-Seq (MACS). (2008)
- Model-based analysis of ChIP-Seq (MACS). (2008)
- Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. (2007)
- Profile of histone lysine methylation across transcribed mammalian chromatin. (2006)
Merged raw entities (7)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| h3k4me3 | drug | 88 | 355 |
| histone h3 lysine 4 trimethylation | drug | 1 | 1 |
| h3k4m3 | drug | — | — |
| h3k4me3 histone mark | drug | — | — |
| histone h3k4me3 | drug | — | — |
| trimethylated histone 3 lysine 4 | drug | — | — |
| trimethylation of histone 3 lysine 4 | drug | — | — |