APOE ε4 allele gene
Evidence from:
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Related entities (5)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| APOE ε4 allele | associated_with | AD subjects | — | 1 |
| APOE ε4 allele | risk_factor_for | Alzheimer's disease | — | 1 |
| APOE ε4 allele | risk_factor_for | Alzheimer’s disease | — | 1 |
| APOE ε4 allele | associated_with | apoE | — | 1 |
| APOE ε4 allele | associated_with | lateral parietal cortex | — | 1 |
Mentioned in (17)
Papers in which this entity is mentioned.
- Genetic Influences on the Developing Young Brain and Risk for Neuropsychiatric Disorders. (2023)
- Longitudinal white matter and cognitive development in pediatric carriers of the apolipoprotein ε4 allele. (2020)
- Imaging structural and functional brain development in early childhood. (2018)
- The development of brain white matter microstructure. (2018)
- Gray matter maturation and cognition in children with different APOE ε genotypes. (2016)
- Genetic Restoration of Plasma ApoE Improves Cognition and Partially Restores Synaptic Defects in ApoE-Deficient Mice. (2016)
- Direct Transcriptional Effects of Apolipoprotein E. (2016)
- Evaluating historical candidate genes for schizophrenia. (2015)
- Brain differences in infants at differential genetic risk for late-onset Alzheimer disease: a cross-sectional imaging study. (2014)
- In vivo and in vitro effects of an apolipoprotein e mimetic peptide on amyloid-β pathology. (2013)
- Amyloid pathway-based candidate gene analysis of [(11)C]PiB-PET in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort. (2012)
- Resting-state network disruption and APOE genotype in Alzheimer's disease: a lagged functional connectivity study. (2012)
- Functional analysis of APOE locus genetic variation implicates regional enhancers in the regulation of both TOMM40 and APOE. (2012)
- Apolipoprotein E: from lipid transport to neurobiology. (2011)
- Neuronal LRP1 knockout in adult mice leads to impaired brain lipid metabolism and progressive, age-dependent synapse loss and neurodegeneration. (2010)
- Network analysis of intrinsic functional brain connectivity in Alzheimer's disease. (2008)
- Two distal downstream enhancers direct expression of the human apolipoprotein E gene to astrocytes in the brain. (2001)
Merged raw entities (4)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| apoe ε4 allele | variant | 17 | 40 |
| apoe 4 allele | gene | — | — |
| apoe*ε4 | gene | — | — |
| apoe ε4 allele | gene | — | — |