TNFα drug
Evidence from:
primary |
all sources
Related entities (20)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| Cd14 | regulates | TNFα | — | 1 |
| chronic alcoholism | risk_factor_for | TNFα | — | 1 |
| ethanol group | regulates | TNFα | — | 1 |
| IFN-γ | regulates | TNFα | — | 1 |
| LIF | protective_against | TNFα | — | 1 |
| LPS | regulates | TNFα | — | 1 |
| TNFα | risk_factor_for | alcohol dependence | — | 1 |
| TNFα | regulates | AMPA receptor | — | 1 |
| TNFα | regulates | AMPA receptors | — | 1 |
| TNFα | protective_against | Amyloid beta | — | 1 |
| TNFα | regulates | Amyloid beta | — | 1 |
| TNFα | expressed_in | brain | — | 1 |
| TNFα | expressed_in | CNS | — | 1 |
| TNFα | expressed_in | cortex | — | 1 |
| TNFα | regulates | GluR1 | — | 1 |
| TNFα | regulates | GRIA1 | 0.01 | 1 |
| TNFα | expressed_in | hippocampus | — | 2 |
| TNFα | regulates | LTP | — | 1 |
| TNFα | regulates | motor cortex | — | 1 |
| TNFα | risk_factor_for | neuroinflammation | — | 1 |
Mentioned in (39)
Papers in which this entity is mentioned.
- Epsin Nanotherapy Regulates Cholesterol Transport to Fortify Atheroma Regression. (2023)
- Chronic oligodendrocyte injury in central nervous system pathologies. (2022)
- Explainable multiview framework for dissecting spatial relationships from highly multiplexed data. (2022)
- Rodent models in placental research. Implications for fetal origins of adult disease. (2022)
- Beneficial Effects of Betaine: A Comprehensive Review. (2021)
- Joint single-cell measurements of nuclear proteins and RNA in vivo. (2021)
- Neurotoxic reactive astrocytes induce cell death via saturated lipids. (2021)
- Simultaneous single cell measurements of intranuclear proteins and gene expression (2021)
- Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations. (2020)
- Genetic compensation triggered by mutant mRNA degradation. (2019)
- Programmed increases in LXRα induced by paternal alcohol use enhance offspring metabolic adaptation to high-fat diet induced obesity. (2019)
- Whole-exome sequencing of cervical carcinomas identifies activating ERBB2 and PIK3CA mutations as targets for combination therapy. (2019)
- Ethanol activates immune response in lymphoblastoid cells. (2019)
- Germline variants associated with leukocyte genes predict tumor recurrence in breast cancer patients. (2019)
- Effects of prenatal alcohol exposure (PAE): insights into FASD using mouse models of PAE. (2018)
- The effect of alcohol on the differential expression of cluster of differentiation 14 gene, associated pathways, and genetic network. (2017)
- Efficient derivation of microglia-like cells from human pluripotent stem cells. (2016)
- Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD. (2016)
- Oxidative stress signaling to chromatin in health and disease. (2016)
- Low Density Lipoprotein Receptor Related Proteins as Regulators of Neural Stem and Progenitor Cell Function. (2016)
- Neuroinflammation and M2 microglia: the good, the bad, and the inflamed. (2014)
- The CXCL12/CXCR4 chemokine ligand/receptor axis in cardiovascular disease. (2014)
- Forebrain engraftment by human glial progenitor cells enhances synaptic plasticity and learning in adult mice. (2013)
- Interleukin-6 (IL-6) receptor/IL-6 fusion protein (Hyper IL-6) effects on the neonatal mouse brain: possible role for IL-6 trans-signaling in brain development and functional neurobehavioral outcomes. (2013)
- Effects of alcohol on the endocrine system. (2013)
- Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases. (2012)
- Plasma cytokine levels in children with autistic disorder and unrelated siblings. (2012)
- Maternal immune activation by LPS selectively alters specific gene expression profiles of interneuron migration and oxidative stress in the fetus without triggering a fetal immune response. (2012)
- Retinoic acid production by endocardium and epicardium is an injury response essential for zebrafish heart regeneration. (2011)
- Protection of neurons and microglia against ethanol in a mouse model of fetal alcohol spectrum disorders by peroxisome proliferator-activated receptor-γ agonists. (2011)
- MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. (2011)
- Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome. (2011)
- Phosphatidylinositol 3-kinase/protein kinase Cdelta activation induces close homolog of adhesion molecule L1 (CHL1) expression in cultured astrocytes. (2010)
- COG1410, an apolipoprotein E-based peptide, improves cognitive performance and reduces cortical loss following moderate fluid percussion injury in the rat. (2010)
- Novel roles for immune molecules in neural development: implications for neurodevelopmental disorders. (2010)
- Cellular metabolic stress: considering how cells respond to nutrient excess. (2010)
- Maternal immune activation alters fetal brain development through interleukin-6. (2007)
- Macrophage-derived tumor necrosis factor alpha, an early developmental signal for motoneuron death. (2004)
- Interleukin-1 is an astroglial growth factor in the developing brain. (1988)
Merged raw entities (2)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| tnfα | drug | 35 | 101 |
| tnfα | gene | 13 | 20 |