COPD phenotype

Aliases: COPD risk, Chronic Obstructive Pulmonary Disease, Chronic obstructive pulmonary disease, GOLD spirometry grade 2 to 4, GOLD-defined COPD, chronic obstructive pulmonary disease, moderate to severe COPD, self-reported COPD

Evidence from: primary | all sources

Related entities (39)

Subject	Relation	Object	p-value	Evidence
CHRNA5	associated_with	COPD	—	1
CHRNA5	risk_factor_for	COPD	—	3
chronic bronchitis	associated_with	COPD	—	1
cigarettes	associated_with	COPD	—	1
cigarettes	risk_factor_for	COPD	—	2
COPD	risk_factor_for	addiction	—	1
COPD	associated_with	asthma	—	1
COPD	associated_with	CAD	—	1
COPD	associated_with	chronic bronchitis	—	1
COPD	associated_with	cigarettes	—	1
COPD	associated_with	emphysema	—	1
COPD	risk_factor_for	nicotine addiction	—	1
COPD	associated_with	osteoporosis	—	1
COPD	associated_with	PLCO	—	1
COPD	associated_with	smoking behaviour	—	1
COPD	associated_with	smoking cessation	—	1
current smoking	associated_with	COPD	—	1
emphysema	associated_with	COPD	—	1
HHIP	risk_factor_for	COPD	—	1
HLA-DQA2	risk_factor_for	COPD	5e-08	1
KANSL1	risk_factor_for	COPD	5e-08	1
men	associated_with	COPD	—	1
nicotine	risk_factor_for	COPD	—	2
NPNT	risk_factor_for	COPD	5e-08	1
PLCO	associated_with	COPD	—	1
rs16969968	associated_with	COPD	—	1
rs16969968	risk_factor_for	COPD	—	1
sex	associated_with	COPD	—	1
smoking	associated_with	COPD	—	1
smoking	risk_factor_for	COPD	—	1
study cohort	associated_with	COPD	—	1
TET2	risk_factor_for	COPD	5e-08	1
time to first cigarette	associated_with	COPD	—	1
time to first cigarette	risk_factor_for	COPD	0.0001	1
Tobacco and Genetics Consortium	associated_with	COPD	—	1
tobacco smoke	risk_factor_for	COPD	—	1
tobacco use	risk_factor_for	COPD	—	1
top SNPs	associated_with	COPD	—	1
women	associated_with	COPD	—	1

Mentioned in (16)

Papers in which this entity is mentioned.

Functional analysis of cancer-associated germline risk variants. (2025)
Single-cell RNA-seq data augmentation using generative Fourier transformer. (2025)
Single-cell analysis of somatic mutations in human bronchial epithelial cells in relation to aging and smoking. (2022)
Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease. (2022)
Detection and characterization of lung cancer using cell-free DNA fragmentomes. (2021)
Prenatal Particulate Air Pollution and DNA Methylation in Newborns: An Epigenome-Wide Meta-Analysis. (2019)
Human Genetics of Addiction: New Insights and Future Directions. (2018)
Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis. (2017)
Time to First Morning Cigarette and Risk of Chronic Obstructive Pulmonary Disease: Smokers in the PLCO Cancer Screening Trial. (2015)
Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank. (2015)
Effects of prenatal exposure to sodium arsenite on motor and food-motivated behaviors from birth to adulthood in C57BL6/J mice. (2012)
Habenular α5 nicotinic receptor subunit signalling controls nicotine intake. (2011)
Clinical practice. Treating smokers in the health care setting. (2011)
Convergence of genetic findings for nicotine dependence and smoking related diseases with chromosome 15q24-25. (2010)
Adrenomedullin signaling is necessary for murine lymphatic vascular development. (2008)
How corticosteroids control inflammation: Quintiles Prize Lecture 2005. (2006)

Merged raw entities (6)

All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.

Raw name	Type	Papers	Mentions
copd	phenotype	16	73
copd risk	phenotype	—	—
gold-defined copd	phenotype	—	—
gold spirometry grade 2 to 4	phenotype	—	—
moderate to severe copd	phenotype	—	—
self-reported copd	phenotype	—	—