Egfr gene

Aliases

Epidermal Growth Factor Receptor, epidermal growth factor receptor

External links

NCBI Gene · Ensembl · GeneCards · UniProt

Related entities (2)

Mentioned in (122)

Papers in which this entity is mentioned.

• Investigation of a global mouse methylome atlas reveals subtype-specific copy number alterations in pediatric cancer models. (2026)
• Nanopore-based cell-free DNA fragmentation and methylation profiles from the cerebral spinal fluid of patients with lung cancer brain metastases. (2025)
• Extrachromosomal DNA-Driven Oncogene Spatial Heterogeneity and Evolution in Glioblastoma. (2025)
• Meta-analysis reveals differences in somatic alterations by genetic ancestry across common cancers. (2025)
• Chromosomal instability as a driver of cancer progression. (2025)
• Functional analysis of cancer-associated germline risk variants. (2025)
• Three-dimensional genome landscape of primary human cancers. (2025)
• Flexynesis: A deep learning toolkit for bulk multi-omics data integration for precision oncology and beyond. (2025)
• Synthetic augmentation of cancer cell line multi-omic datasets using unsupervised deep learning. (2024)
• The landscape of drug sensitivity and resistance in sarcoma. (2024)
• Insights for precision oncology from the integration of genomic and clinical data of 13,880 tumors from the 100,000 Genomes Cancer Programme. (2024)
• Analysis of 10,478 cancer genomes identifies candidate driver genes and opportunities for precision oncology. (2024)
• The Application of Long-Read Sequencing to Cancer. (2024)
• Choline-An Underappreciated Component of a Mother-to-Be's Diet. (2024)
• A New Era of Data-Driven Cancer Research and Care: Opportunities and Challenges. (2024)
• Combination of genomic instability score and TP53 status for prognosis prediction in lung adenocarcinoma. (2023)
• Machine learning for genetics-based classification and treatment response prediction in cancer of unknown primary. (2023)
• Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA. (2022)
• Explainable multiview framework for dissecting spatial relationships from highly multiplexed data. (2022)
• Detecting cell-of-origin and cancer-specific methylation features of cell-free DNA from Nanopore sequencing. (2022)
• Integrating molecular profiles into clinical frameworks through the Molecular Oncology Almanac to prospectively guide precision oncology. (2021)
• Application of third-generation sequencing in cancer research. (2021)
• Therapeutic Implications of Germline Testing in Patients With Advanced Cancers. (2021)
• Integrative reconstruction of cancer genome karyotypes using InfoGenomeR. (2021)
• Detection and characterization of lung cancer using cell-free DNA fragmentomes. (2021)
• Choline Kinase: An Unexpected Journey for a Precision Medicine Strategy in Human Diseases. (2021)
• Potential Role of S-Palmitoylation in Cancer Stem Cells of Lung Adenocarcinoma. (2021)
• Macrophage Polarization States in the Tumor Microenvironment. (2021)
• Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes. (2021)
• : batch effect adjustment for RNA-seq count data. (2020)
• Pan-cancer analysis of whole genomes. (2020)
• Distinct Classes of Complex Structural Variation Uncovered across Thousands of Cancer Genome Graphs. (2020)
• Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers. (2020)
• PKA and Ube3a regulate SK2 channel trafficking to promote synaptic plasticity in hippocampus: Implications for Angelman Syndrome. (2020)
• AmpliconReconstructor integrates NGS and optical mapping to resolve the complex structures of focal amplifications. (2020)
• Comprehensive germline genomic profiles of children, adolescents and young adults with solid tumors. (2020)
• Longitudinal therapy monitoring of ALK-positive lung cancer by combined copy number and targeted mutation profiling of cell-free DNA. (2020)
• Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers. (2019)
• CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. (2019)
• Exploring the landscape of focal amplifications in cancer using AmpliconArchitect. (2019)
• Tumor mutational burden standardization initiatives: Recommendations for consistent tumor mutational burden assessment in clinical samples to guide immunotherapy treatment decisions. (2019)
• VCF2CNA: A tool for efficiently detecting copy-number alterations in VCF genotype data and tumor purity. (2019)
• Assessment of tumor mutation burden calculation from gene panel sequencing data. (2019)
• The role and robustness of the Gini coefficient as an unbiased tool for the selection of Gini genes for normalising expression profiling data. (2019)
• Pan-cancer whole-genome analyses of metastatic solid tumours. (2019)
• Circular DNA elements of chromosomal origin are common in healthy human somatic tissue. (2018)
• The Cancer Spliceome: Reprograming of Alternative Splicing in Cancer. (2018)
• Driver Fusions and Their Implications in the Development and Treatment of Human Cancers. (2018)
• Detection of Somatic Structural Variants Enables Quantification and Characterization of Circulating Tumor DNA in Children With Solid Tumors. (2018)
• Widespread Selection for Oncogenic Mutant Allele Imbalance in Cancer. (2018)
• Comprehensive Characterization of Cancer Driver Genes and Mutations. (2018)
• Complex rearrangements and oncogene amplifications revealed by long-read DNA and RNA sequencing of a breast cancer cell line. (2018)
• The Immune Landscape of Cancer. (2018)
• Comprehensive Cancer-Predisposition Gene Testing in an Adult Multiple Primary Tumor Series Shows a Broad Range of Deleterious Variants and Atypical Tumor Phenotypes. (2018)
• Tumor fraction in cell-free DNA as a biomarker in prostate cancer. (2018)
• Clinical cancer genomic profiling by three-platform sequencing of whole genome, whole exome and transcriptome. (2018)
• SvABA: genome-wide detection of structural variants and indels by local assembly. (2018)
• Patterns and mechanisms of structural variations in human cancer. (2018)
• Copy number signatures and mutational processes in ovarian carcinoma. (2018)
• OncoKB: A Precision Oncology Knowledge Base. (2017)
• Universal Patterns of Selection in Cancer and Somatic Tissues. (2017)
• Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma. (2017)
• Cerebral organoids reveal early cortical maldevelopment in schizophrenia-computational anatomy and genomics, role of FGFR1. (2017)
• Integrative clustering of multi-level 'omic data based on non-negative matrix factorization algorithm. (2017)
• Integrated analysis of gene expression and copy number identified potential cancer driver genes with amplification-dependent overexpression in 1,454 solid tumors. (2017)
• A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles. (2017)
• Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients. (2017)
• Interaction of glycosphingolipids GD3 and GD2 with growth factor receptors maintains breast cancer stem cell phenotype. (2017)
• Copy-number signatures and mutational processes in ovarian carcinoma (2017)
• Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity. (2017)
• Integrated digital error suppression for improved detection of circulating tumor DNA. (2016)
• Fragment Length of Circulating Tumor DNA. (2016)
• The clinical trial landscape in oncology and connectivity of somatic mutational profiles to targeted therapies. (2016)
• Maternal dietary intake of choline in mice regulates development of the cerebral cortex in the offspring. (2016)
• Possible relationship between common genetic variation and white matter development in a pilot study of preterm infants. (2016)
• Development and clinical application of an integrative genomic approach to personalized cancer therapy. (2016)
• Establishment of human iPSC-based models for the study and targeting of glioma initiating cells. (2016)
• Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets. (2015)
• Recurrent somatic mutations in regulatory regions of human cancer genomes. (2015)
• Germline Mutations in Predisposition Genes in Pediatric Cancer. (2015)
• Cytochrome P450 1B1: An unexpected modulator of liver fatty acid homeostasis. (2015)
• Glucose-dependent acetylation of Rictor promotes targeted cancer therapy resistance. (2015)
• Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank. (2015)
• Dissecting FASD through the global transcriptome. (2015)
• MBASED: allele-specific expression detection in cancer tissues and cell lines. (2014)
• Unraveling the clonal hierarchy of somatic genomic aberrations. (2014)
• MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens. (2014)
• Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies. (2014)
• Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine. (2014)
• The CXCL12/CXCR4 chemokine ligand/receptor axis in cardiovascular disease. (2014)
• An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage. (2014)
• Involvement of p53 in the repair of DNA double strand breaks: multifaceted Roles of p53 in homologous recombination repair (HRR) and non-homologous end joining (NHEJ). (2014)
• Clonal evolution in hematological malignancies and therapeutic implications. (2014)
• DNA-Mutation Inventory to Refine and Enhance Cancer Treatment (DIRECT): a catalog of clinically relevant cancer mutations to enable genome-directed anticancer therapy. (2013)
• Cancer genome landscapes. (2013)
• The sox family of transcription factors: versatile regulators of stem and progenitor cell fate. (2013)
• Cornichon proteins determine the subunit composition of synaptic AMPA receptors. (2013)
• Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. (2013)
• A critical role for PDGFRα signaling in medial nasal process development. (2013)
• A rare population of CD24(+)ITGB4(+)Notch(hi) cells drives tumor propagation in NSCLC and requires Notch3 for self-renewal. (2013)
• Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas. (2013)
• Emerging landscape of oncogenic signatures across human cancers. (2013)
• Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. (2013)
• Differential expression profiles of glycosphingolipids in human breast cancer stem cells vs. cancer non-stem cells. (2013)
• Pan-cancer patterns of somatic copy number alteration. (2013)
• Zebrafish models of human liver development and disease. (2013)
• High-throughput detection of actionable genomic alterations in clinical tumor samples by targeted, massively parallel sequencing. (2012)
• Microsatellites with macro-influence in ewing sarcoma. (2012)
• Patient-derived tumour xenografts as models for oncology drug development. (2012)
• Cranial neural crest cells on the move: their roles in craniofacial development. (2011)
• Copy number variation detection in whole-genome sequencing data using the Bayesian information criterion. (2011)
• Zebrafish as a model to study cardiac development and human cardiac disease. (2011)
• Sonic hedgehog signaling is decoded by calcium spike activity in the developing spinal cord. (2011)
• Alteration of gene expression by alcohol exposure at early neurulation. (2011)
• DNA copy number, including telomeres and mitochondria, assayed using next-generation sequencing. (2010)
• Normal development of brain circuits. (2010)
• rSW-seq: algorithm for detection of copy number alterations in deep sequencing data. (2010)
• Cellular metabolic stress: considering how cells respond to nutrient excess. (2010)
• Cancer-specific high-throughput annotation of somatic mutations: computational prediction of driver missense mutations. (2009)
• A structural MRI study of human brain development from birth to 2 years. (2008)
• Neuregulin 1 in neural development, synaptic plasticity and schizophrenia. (2008)
• Detergent-resistant membranes and the protein composition of lipid rafts. (2003)

Merged raw entities (2)

All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.