LDLR gene
Evidence from:
primary |
all sources
Related entities (6)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| HDL cholesterol | regulates | LDLR | — | 1 |
| LDLR | associated_with | complex diseases | — | 1 |
| LDLR | risk_factor_for | dyslipidemia | — | 1 |
| LDLR | associated_with | lipid levels | — | 1 |
| LDLR | associated_with | statins | — | 1 |
| SREBF2 | regulates | LDLR | — | 1 |
Mentioned in (23)
Papers in which this entity is mentioned.
- Advancing regulatory variant effect prediction with AlphaGenome. (2026)
- Specificity, length and luck drive gene rankings in association studies. (2026)
- A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies. (2025)
- Epsin Nanotherapy Regulates Cholesterol Transport to Fortify Atheroma Regression. (2023)
- A statistical framework for powerful multi-trait rare variant analysis in large-scale whole-genome sequencing studies. (2023)
- Beneficial Effects of Betaine: A Comprehensive Review. (2021)
- Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression. (2021)
- Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector. (2018)
- ApoE Regulates the Development of Adult Newborn Hippocampal Neurons. (2018)
- ApoE, ApoE Receptors, and the Synapse in Alzheimer's Disease. (2017)
- The ApoE receptors Vldlr and Apoer2 in central nervous system function and disease. (2017)
- Smoothened determines β-arrestin-mediated removal of the G protein-coupled receptor Gpr161 from the primary cilium. (2016)
- Low Density Lipoprotein Receptor Related Proteins as Regulators of Neural Stem and Progenitor Cell Function. (2016)
- The CXCL12/CXCR4 chemokine ligand/receptor axis in cardiovascular disease. (2014)
- FGF21 promotes metabolic homeostasis via white adipose and leptin in mice. (2012)
- A comparison of approaches to account for uncertainty in analysis of imputed genotypes. (2011)
- MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins. (2011)
- Apolipoprotein E: from lipid transport to neurobiology. (2011)
- Genetics of psychiatric disorders methods: molecular approaches. (2010)
- Neuronal LRP1 knockout in adult mice leads to impaired brain lipid metabolism and progressive, age-dependent synapse loss and neurodegeneration. (2010)
- Finding the missing heritability of complex diseases. (2009)
- 3' end mRNA processing: molecular mechanisms and implications for health and disease. (2008)
- Two distal downstream enhancers direct expression of the human apolipoprotein E gene to astrocytes in the brain. (2001)
Merged raw entities (4)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| ldlr | gene | 23 | 48 |
| ldl receptor | gene | 1 | 1 |
| ldl-receptor | gene | — | — |
| ldl-receptor mutations | gene | — | — |